Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Cervical spine motion in manual versus Jackson table turning methods in a cadaveric global instability model. | STUDY DESIGN: A study of spine biomechanics in a cadaver model.OBJECTIVE: To quantify motion in multiple axes created by transfer methods from stretcher to operating table in the prone position in a cervical global instability model.SUMMARY OF THE BACKGROUND DATA: Patients with an unstable cervical spine remain at high... | ['Biomechanical Phenomena', 'Cadaver', 'Cervical Vertebrae', 'Humans', 'Joint Instability', 'Operating Rooms', 'Range of Motion, Articular', 'Rotation', 'Supine Position', 'Surgical Equipment', 'Transportation of Patients'] | 18,525,488 | [['G01.154.090', 'G01.374.089'], ['C23.550.260.224'], ['A02.835.232.834.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['N02.278.388.700'], ['E01.370.600.700', 'G11.427.760'], ['G01.482.703'], ['G11.427.695.625'], ['E07.858'], ['E02.365.839', 'N02.421.297.879']] | ['Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Diagnosis of pseudoaneurysm of the ascending aorta after implantation of a valved conduit by multiplane transesophageal echocardiography]. | In a 48-year-old male patient with Marfan syndrome who underwent composite graft replacement of the ascending aorta and the aortic valve with reimplantation of the coronary arteries a cardiac enlargement was detected by routine chest x-ray. Transthoracal echocardiography showed a pseudoaneurysm around the composite gra... | ['Aneurysm, False', 'Aortic Aneurysm, Thoracic', 'Aortic Valve Insufficiency', 'Blood Vessel Prosthesis', 'Echocardiography, Transesophageal', 'Follow-Up Studies', 'Graft Occlusion, Vascular', 'Heart Valve Prosthesis', 'Humans', 'Male', 'Marfan Syndrome', 'Middle Aged', 'Postoperative Complications', 'Reoperation'] | 7,975,811 | [['C14.907.055.090'], ['C14.907.055.239.125', 'C14.907.109.139.125'], ['C14.280.484.048.500'], ['E07.695.110'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C23.550.767.400'], ['E07.695.310... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Endosulfan upregulates AP-1 binding and ARE-mediated transcription via ERK1/2 and p38 activation in HepG2 cells. | Endosulfan is an organochlorine insecticide and has been implicated in neurotoxicity, hepatotoxicity, immunosuppression and teratogenicity. However, the molecular mechanism of endosulfan toxicity is not yet clear. Recent studies demonstrated that oxidative stress induced by endosulfan is involved in its toxicity and ac... | ['Endosulfan', 'Enzyme Activation', 'Hep G2 Cells', 'Humans', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated Protein Kinase 3', 'Transcription Factor AP-1', 'Transcription, Genetic', 'Transcriptional Activation', 'Up-Regulation', 'p38 Mitogen-Activated Protein Kinases'] | 22,146,149 | [['D02.886.092.408', 'D03.633.100.197.408'], ['G02.111.263', 'G03.328'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.567.249.500', 'D12.644.360.450.169.500', 'D12.776.476.450.169.500'], ['D08.811.913.696.620.682.700.567.249.750', 'D12.644.36... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A qualitative study among injection drug using women in Rhode Island: attitudes toward testing, treatment, and vaccination for hepatitis and HIV. | HIV and hepatitis C virus infection are serious and prevalent health conditions among many women who inject drugs. Qualitative interviews with 20 injection drug using women at a short term drug treatment center in Rhode Island revealed six primary barriers and facilitators for testing and receiving results and treatmen... | ['AIDS Serodiagnosis', 'Adult', 'Attitude to Health', 'Female', 'HIV Infections', 'Health Services Accessibility', 'Hepatitis B', 'Hepatitis B Vaccines', 'Hepatitis C', 'Humans', 'Interviews as Topic', 'Substance Abuse, Intravenous', 'Vaccination'] | 18,095,839 | [['E01.370.225.812.735.060', 'E01.370.225.875.408.500', 'E05.200.812.735.060', 'E05.200.875.408.500', 'E05.478.594.760.060'], ['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['N04.590.374.350', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Everolimus dramatically improves glycemic control in unresectable metastatic insulinoma: a case report. | Hypoglycemia poses a significant management challenge in patients with unresectable metastatic insulinoma. A 57-year-old woman with pancreatic neuroendocrine tumor with multiple liver metastases was referred to our institution. During the clinical course of pancreatic neuroendocrine tumor, she had experienced palpitati... | ['Administration, Oral', 'Antineoplastic Agents', 'Blood Glucose', 'Drug Administration Schedule', 'Everolimus', 'Female', 'Humans', 'Hypoglycemia', 'Insulin', 'Insulinoma', 'Japan', 'Liver Neoplasms', 'Middle Aged', 'Pancreatic Neoplasms', 'Quality of Life', 'Sirolimus', 'Tomography, X-Ray Computed', 'Treatment Outcom... | 24,367,043 | [['E02.319.267.100'], ['D27.505.954.248'], ['D09.947.875.359.448.500'], ['E02.319.283'], ['D02.540.505.760.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.984'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['C04.557.470.035.100.852', 'C04.588.274.761.249.500', 'C04.588.322.475.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Rate and onset cues can improve cochlear implant synthetic vowel recognition in noise. | Understanding speech-in-noise is difficult for most cochlear implant (CI) users. Speech-in-noise segregation cues are well understood for acoustic hearing but not for electric hearing. This study investigated the effects of stimulation rate and onset delay on synthetic vowel-in-noise recognition in CI subjects. In expe... | ['Acoustic Stimulation', 'Adult', 'Aged', 'Analysis of Variance', 'Audiometry, Speech', 'Case-Control Studies', 'Cochlear Implantation', 'Cochlear Implants', 'Comprehension', 'Correction of Hearing Impairment', 'Cues', 'Electric Stimulation', 'Female', 'Humans', 'Loudness Perception', 'Male', 'Middle Aged', 'Noise', 'P... | 23,464,025 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.382.375.060.060'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E04.580.450.220', 'E04.650.220'], ['E07.305.250.319.381.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis and evaluation of water-soluble paclitaxel prodrugs. | A series of water-soluble 2'-paclitaxel prodrugs were synthesized by attaching paclitaxel to polyethylene glycol (PEG) through amino acid spacers. The prodrugs showed highly improved water solubility, enhanced in vitro cytotoxicity and in vivo antitumor activity compared with the native drug, paclitaxel. | ['Animals', 'Antineoplastic Agents', 'Cell Survival', 'Cross-Linking Reagents', 'Drug Screening Assays, Antitumor', 'Humans', 'Mice', 'Mice, Nude', 'Neoplasms, Experimental', 'Paclitaxel', 'Polyethylene Glycols', 'Prodrugs', 'Solubility', 'Structure-Activity Relationship', 'Treatment Outcome', 'Tumor Cells, Cultured'] | 12,392,737 | [['B01.050'], ['D27.505.954.248'], ['G04.346'], ['D27.720.470.410.210'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.500'], ['C04.619', 'E05.598.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Inactivation mechanisms of pathogenic bacteria in several matrixes during the composting process in a composting toilet. | This study aimed to compare the inactivation rate and the mechanisms of pathogenic bacteria in three matrixes (sawdust, rice husk and charcoal) during the composting process. The inactivation rate was evaluated with Escherichia coli strain and the damaged parts and/or functions were evaluated with three different media... | ['Agar', 'Animals', 'Bacteria', 'Biodegradation, Environmental', 'Charcoal', 'Escherichia coli', 'Feces', 'Hydrogen-Ion Concentration', 'Oryza', 'Sewage', 'Soil', 'Soybeans', 'Swine', 'Trypsin', 'Wood'] | 24,645,447 | [['D09.698.360.041'], ['B01.050'], ['B03'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D01.268.150.150'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['A12.459'], ['G02.300'], ['B01.650.940.800.575.912.250.822.616'], ['D20.944.932.500'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
On the diurnal rhythm of activity of Oryctolagus cuniculus (Linne, 1758). | The diurnal rhythm of activity of the rabbit (Oryctolagus cuniculus (Linn?, 1758)) is examined under artificial and natural circumstances. Two male rabbits were examined actographically in special registration cages in artificial and natural light. A population of rabbits was observed in nature and its rhythm of activi... | ['Animals', 'Circadian Rhythm', 'Feeding Behavior', 'Female', 'Housing, Animal', 'Light', 'Male', 'Population', 'Rabbits'] | 1,172,366 | [['B01.050'], ['G07.180.562.190'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['J03.340.250', 'N06.230.150.360.250'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['N01.600'], ['B01.050.150.900.649.313.968.700']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Biochemical characterization of mouse brain necdin. | Necdin is a protein encoded by neural differentiation-specific mRNA derived from embryonal carcinoma cells (P19). Necdin of mouse brain was characterized by Western blotting and silver-staining analysis by using affinity purified antibodies to 17 synthetic peptides of deduced C-terminal amino acids. Necdin exhibits a m... | ['Aging', 'Animals', 'Blotting, Western', 'Brain', 'Brain Chemistry', 'Carcinoma, Embryonal', 'Cell Line', 'Cell Nucleus', 'Centrifugation, Density Gradient', 'Chromatography, Affinity', 'Chromatography, Gel', 'Electrophoresis, Gel, Two-Dimensional', 'Electrophoresis, Polyacrylamide Gel', 'Isoelectric Focusing', 'Mice'... | 8,615,786 | [['G07.345.124'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A08.186.211'], ['G02.111.150', 'G03.185'], ['C04.557.465.200'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E05.181.724.336', 'E05.196.941.336'], ['E05.196.181... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Photoperiodic control of antler cycles in deer. V. Reversed seasons. | Newborn and weanling fawns were held under reversed annual light cycles to learn if the subsequent replacement of their antlers would coincide with the anniversary of their births, as occurs in nature, or adapt to the artificial seasons of increasing day lengths even when these fall at the "wrong" time of year. The fir... | ['Age Factors', 'Animals', 'Antlers', 'Deer', 'Horns', 'Light', 'Male', 'Seasons'] | 7,400,761 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['A13.507.288'], ['B01.050.150.900.649.313.500.380.373'], ['A13.507'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525']] | ['Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Phenolic constituents from Perovskia atriplicifolia. | Perovskoate, an isorinic acid derivative (1) and perovskoside, the catechol derivative (2) have been isolated from the ethyl acetate soluble fraction of the whole plant of Perovskia atriplicifolia and assigned the structure 3(7-hydroxyphenyl)-2-hydroxy propanoic acid; (R)-form, 2-O-(6',7'-dihydroxy-E-cinnamoyl) (1) and... | ['Caffeic Acids', 'Catechols', 'Cholinesterase Inhibitors', 'Coumaric Acids', 'Inhibitory Concentration 50', 'Lactates', 'Lamiaceae', 'Lipoxygenase Inhibitors', 'Models, Molecular', 'Molecular Structure', 'Phenols', 'Propionates'] | 16,644,529 | [['D02.241.223.200.054'], ['D02.455.426.559.389.657.166'], ['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['D02.241.223.200.210'], ['E05.940.350', 'G07.690.936.563'], ['D02.241.511.459'], ['B01.650.940.800.575.912.250.583.520'], ['D27.505.519.389.480'], ['E05.599.595'], ['G02.111.570', '... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Suppression of HSP70 expression sensitizes NSCLC cell lines to TRAIL-induced apoptosis by upregulating DR4 and DR5 and downregulating c-FLIP-L expressions. | Many cancer cell types are resistant to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis. Here, we examined whether HSP70 suppression by small interfering RNA (siRNA) sensitized non-small cell lung cancer (NSCLC) cells to TRAIL-induced apoptosis and the underlying mechanisms. We demonst... | ['Animals', 'Antineoplastic Agents', 'Apoptosis', 'CASP8 and FADD-Like Apoptosis Regulating Protein', 'Carcinoma, Non-Small-Cell Lung', 'Cell Line, Tumor', 'Down-Regulation', 'HSP70 Heat-Shock Proteins', 'Humans', 'Lung Neoplasms', 'Mice', 'Mice, Nude', 'RNA, Small Interfering', 'Receptors, TNF-Related Apoptosis-Induci... | 22,948,392 | [['B01.050'], ['D27.505.954.248'], ['G04.146.954.035'], ['D12.644.360.024.285.024', 'D12.644.360.024.500.024', 'D12.644.360.075.421.024', 'D12.776.157.057.018.024', 'D12.776.476.075.421.024'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['A11.251.210.190', 'A11.251.860.180'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Voclosporin food effect and single oral ascending dose pharmacokinetic and pharmacodynamic studies in healthy human subjects. | Voclosporin (VCS) is a novel calcineurin (CN) inhibitor intended for prevention of organ graft rejection and treatment of lupus nephritis. These studies evaluated the single ascending dose pharmacokinetics (PK) and pharmacodynamics (PD, CN activity) of VCS and the effect of food. VCS was administered orally in single d... | ['Adolescent', 'Adult', 'Calcineurin Inhibitors', 'Cross-Over Studies', 'Cyclosporine', 'Diet, Fat-Restricted', 'Diet, High-Fat', 'Double-Blind Method', 'Enzyme Inhibitors', 'Fasting', 'Female', 'Food-Drug Interactions', 'Healthy Volunteers', 'Humans', 'Male', 'Middle Aged', 'Young Adult'] | 23,736,966 | [['M01.060.057'], ['M01.060.116'], ['D27.505.519.389.174'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['E02.642.249.260', 'G07.203.650.240.260'], ['G07.203.650.240.267'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A novel and easy-to-prepare strontium(II) modified calcium phosphate bone cement with enhanced mechanical properties. | The aim of this study was to evaluate two different approaches to obtaining strontium-modified calcium phosphate bone cements (SrCPCs) without elaborate synthesis of Sr-containing calcium phosphate species as cement precursors that could release biologically effective doses of Sr(2+) and thus could improve the healing ... | ['Bone Cements', 'Calcium Phosphates', 'Compressive Strength', 'Elastic Modulus', 'Hardness', 'Materials Testing', 'Porosity', 'Strontium', 'Tensile Strength', 'Viscosity'] | 23,523,939 | [['D05.750.716.822.300', 'D25.720.716.822.300', 'D27.720.102.158', 'J01.637.051.720.716.822.300'], ['D01.029.260.700.675.374.075', 'D01.146.360', 'D01.695.625.675.650.075'], ['G01.374.180'], ['G01.374.590.605'], ['G01.374.647'], ['E05.570'], ['G01.374.710'], ['D01.268.552.850', 'D01.268.556.825', 'D01.552.539.861', 'D0... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Regulation of rat cytochrome P450C24 (CYP24) gene expression. Evidence for functional cooperation of Ras-activated Ets transcription factors with the vitamin D receptor in 1,25-dihydroxyvitamin D(3)-mediated induction. | Transcription of the rat CYP24 gene is induced by 1, 25-dihydroxyvitamin D(3) (1,25-(OH)(2)D(3)) through two vitamin D response elements (VDREs). A functional Ras-dependent Ets-binding site (EBS) was located downstream from the proximal VDRE and was critical to 1,25(OH)(2)D(3)-mediated induction. Cotransfection of Ets-... | ['Animals', 'Binding Sites', 'Calcitriol', 'Cytochrome P-450 Enzyme System', 'Dimerization', 'Gene Expression Regulation, Enzymologic', 'Nuclear Proteins', 'Promoter Regions, Genetic', 'Protein Binding', 'Proto-Oncogene Protein c-ets-1', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-ets', 'Proto-Oncogene Protei... | 10,617,584 | [['B01.050'], ['G02.111.570.120'], ['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.300', 'D04.210.500.812.768.196.478.387.300', 'D10.570.938.146.478.387.300'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['G02.206', 'G03.230'], ['G05.308.320'], ['D12.776.660'], ['G02.111.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Imaging the central conducting lymphatics: initial experience with dynamic MR lymphangiography. | PURPOSE: To describe a dynamic magnetic resonance (MR) lymphangiography technique after intranodal injection of gadolinium-based contrast agent and to assess its feasibility for evaluation of the central conducting lymphatics (CCL) in patients with pathologic disorders that involve the CCL.MATERIALS AND METHODS: A retr... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Contrast Media', 'Feasibility Studies', 'Female', 'Gadolinium DTPA', 'Humans', 'Injections, Intralesional', 'Lymphatic Diseases', 'Lymphatic Vessels', 'Lymphography', 'Magnetic Resonance Imaging', 'Male', 'Retrospective Studies', 'Young Adult'] | 25,325,323 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['D27.505.259.500', 'D27.720.259'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['D02.092.782.590.401', 'D02.241.081.018.639.400', 'D02.257.141'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Acute respiratory distress syndrome following cutaneous exposure to Lysol: a case report. | Lysol (mixed cresols) is a brand of popular detergent commonly used to disinfect toilets and floors in Taiwan. We report a patient with acute respiratory failure immediately following chemical burns caused by skin contact with Lysol solution. On admission, chest radiography showed bilateral diffuse pulmonary infiltrate... | ['Adult', 'Cresols', 'Disinfectants', 'Female', 'Humans', 'Respiratory Distress Syndrome', 'Skin'] | 10,634,006 | [['M01.060.116'], ['D02.455.426.559.389.657.239'], ['D27.505.954.122.425', 'D27.720.274'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.840', 'C08.618.840'], ['A17.815']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Proteomic characterization of Helicobacter pylori CagA antigen recognized by child serum antibodies and its epitope mapping by peptide array. | Serum antibodies against pathogenic bacteria play immunologically protective roles, and can be utilized as diagnostic markers of infection. This study focused on Japanese child serum antibodies against Helicobacter pylori, a chronically-infected gastric bacterium which causes gastric cancer in adults. Serological diagn... | ['Antigens, Bacterial', 'Bacterial Proteins', 'Child', 'Child, Preschool', 'Epitope Mapping', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Proteomics'] | 25,141,238 | [['D23.050.161'], ['D12.776.097'], ['M01.060.406'], ['M01.060.406.448'], ['E05.478.274', 'E05.601.690.300'], ['C01.150.252.400.466'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.12... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Zombie tapeworms in late capitalism: accelerating clinical and reproductive labour in Mira Grant's Parasitology Trilogy. | Biomedicine is increasingly shaped by the speculative economical values of neoliberal capitalism. A key feature of this new bioeconomical regime is the patenting and circulation of organisms and tissue samples, allowing rapid commercialisation of bacterial, animal and human biomedical materials. When thinking about thi... | ['Animals', 'Biomedical Research', 'Biotechnology', 'Capitalism', 'Cestoda', 'Commerce', 'Delivery of Health Care', 'Humans', 'Literature, Modern', 'Parasitology', 'Reproduction', 'Science', 'Work'] | 27,559,055 | [['B01.050'], ['H01.770.644.145'], ['H01.158.550', 'J01.897.120'], ['I01.261.100', 'I01.696.100'], ['B01.050.500.500.736.215'], ['J01.219'], ['N04.590.374', 'N05.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.517.533'], ['H01.158.273.688'], ['G08.686.784'], ['H01.770'], ['I03.946']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Humanities [K]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 |
Analysis of a firn core for assessing POP seasonal accumulation on an Alpine glacier. | Organochlorine pesticides (DDTs, HCHs, HCB) and selected PCBs were analyzed in samples from a firn core drilled on the Lys Glacier (4240 m above sea level, Monte Rosa Group, Italian Alps) in Summer 2000. The samples covered a relatively short time interval (from 1997 to 2000) and a seasonal detail breakdown was possibl... | ['Environmental Monitoring', 'Environmental Pollutants', 'Hydrocarbons, Chlorinated', 'Ice Cover', 'Italy', 'Pesticides', 'Seasons'] | 16,023,724 | [['N06.850.460.350.080', 'N06.850.780.375'], ['D27.888.284'], ['D02.455.526.439'], ['G01.311.400', 'G16.500.275.410.500', 'N06.230.291.500'], ['Z01.542.489'], ['D27.720.031.700', 'D27.888.723'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525']] | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[The anastomotic loop between recurrent laryngeal nerves: an anatomic reality]. | The authors present the result of an anatomical study carried out on human laryngeal nerves. During the study, stressed not only were classic anatomical data relating to the morphology of the nervous system of the larynx, evidentiated and photographically documented, but the constant presence of an anastomotic nervous ... | ['Aged', 'Anastomosis, Surgical', 'Cadaver', 'Female', 'Humans', 'Laryngeal Nerves', 'Larynx', 'Male', 'Middle Aged'] | 8,165,895 | [['M01.060.116.100'], ['E04.035'], ['C23.550.260.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.050.050.925.450', 'A08.800.050.600.825.450', 'A08.800.800.060.920.450', 'A08.800.800.120.900.450'], ['A04.329'], ['M01.060.116.630']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Black thyroid: report of an autopsy case. | A distinctive but very rare side effect of exposure to minocycline is black pigmentation of the thyroid gland. Until 2002, not more than 30 cases of black thyroid had been reported in the English literature. We report on a 24-year-old woman with known antemortem ingestion of minocycline. The woman suffered from a depre... | ['Adult', 'Anti-Bacterial Agents', 'Female', 'Forensic Pathology', 'Head Injuries, Penetrating', 'Humans', 'Minocycline', 'Pigmentation', 'Suicide', 'Thyroid Gland', 'Wounds, Gunshot'] | 16,151,826 | [['M01.060.116'], ['D27.505.954.122.085'], ['H02.403.330.300', 'H02.403.650.249', 'I01.198.780.937.460'], ['C10.900.300.675', 'C26.915.300.475', 'C26.986.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.847.562.900.550', 'D04.615.562.900.550'], ['E01.370.600.620', 'G16.690'], ['F01.145.126.980.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Ana... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
Silica binds serum proteins resulting in a shift of the dose-response for silica-induced chemokine expression in an alveolar type II cell line. | There is a growing concern about whether the myriad of culture conditions, cell lines, and doses of nonfibrous and fibrous particles used in vitro are truly representative of the complex environment of the in vivo particle exposure situation. The use of serum as a supplement to the growth medium of cultured cells is a ... | ['Animals', 'Apolipoprotein A-I', 'Blood Proteins', 'Blotting, Western', 'Cells, Cultured', 'Chemokines', 'Electrophoresis, Agar Gel', 'Electrophoresis, Polyacrylamide Gel', 'In Vitro Techniques', 'Macrophages, Alveolar', 'Mice', 'Mice, Inbred C57BL', 'Pulmonary Alveoli', 'RNA, Messenger', 'Serum Albumin', 'Silicon Dio... | 10,581,205 | [['B01.050'], ['D10.532.091.200.100', 'D12.776.070.400.200.100', 'D12.776.521.120.200.100'], ['D12.776.124'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chronic carbamazepine selectively downregulates cytosolic phospholipase A2 expression and cyclooxygenase activity in rat brain. | BACKGROUND: Carbamazepine is a mood stabilizer used as monotherapy or as an adjunct to lithium in the treatment of acute mania or the prophylaxis of bipolar disorder. Based on evidence that lithium and valproate, other mood stabilizers, reduce brain arachidonic acid turnover and its conversion via cyclooxygenase to pro... | ['Analgesics, Non-Narcotic', 'Animals', 'Blotting, Western', 'Brain', 'Brain Chemistry', 'Carbamazepine', 'Chromatography, High Pressure Liquid', 'Cytosol', 'Down-Regulation', 'Eicosanoids', 'Male', 'Phospholipases A', 'Phospholipases A2', 'Prostaglandin-Endoperoxide Synthases', 'RNA, Messenger', 'Rats', 'Rats, Inbred ... | 15,312,812 | [['D27.505.696.663.850.014.040', 'D27.505.954.427.040.100'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A08.186.211'], ['G02.111.150', 'G03.185'], ['D03.633.300.240.127'], ['E05.196.181.400.300'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treatment of complex foot deformities in children with the taylor spatial frame. | The Taylor spatial frame is a relatively new external fixator able to correct 6-axis deformities with computer accuracy using a virtual hinge. The Taylor spatial frame has gained tremendous popularity, but its use for the correction of foot deformities is still limited. Various ring configurations and a new foot progra... | ['Adolescent', 'Bone Nails', 'Bone Screws', 'Child', 'Child, Preschool', 'Equipment Design', 'Equipment Failure Analysis', 'External Fixators', 'Female', 'Foot Deformities', 'Humans', 'Male', 'Treatment Outcome'] | 19,226,012 | [['M01.060.057'], ['E07.695.370.249', 'E07.858.442.660.460.249', 'E07.858.690.725.460.249'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['M01.060.406'], ['M01.060.406.448'], ['E05.320'], ['E05.325.192'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['C05.330'], ['B01.050.150.900.649.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Long noncoding RNA H19 mediates melatonin inhibition of premature senescence of c-kit(+) cardiac progenitor cells by promoting miR-675. | Melatonin, a hormone secreted by the pineal gland, possesses multiple biological activities such as antitumor, antioxidant, and anti-ischemia. C-kit(+) cardiac progenitor cells (CPCs) have emerged as a promising tool for the treatment of heart diseases. However, the senescence of CPCs due to pathological stimuli leads ... | ["3' Untranslated Regions", 'Animals', 'Cellular Senescence', 'Gene Knockdown Techniques', 'Hydrogen Peroxide', 'Melatonin', 'Mice', 'MicroRNAs', 'Myocytes, Cardiac', 'Proto-Oncogene Proteins c-kit', 'RNA, Long Noncoding', 'Stem Cells', 'Ubiquitin Thiolesterase'] | 27,062,045 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['B01.050'], ['G04.043'], ['E05.393.335.500'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D03.633.100.473.914.481', 'D06.472.506'], ['B01.05... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mass spectrometric characterization of black tea thearubigins leading to an oxidative cascade hypothesis for thearubigin formation. | Thearubigins are the most abundant group of phenolic pigments found in black tea, accounting for an estimated 60-70% of the solids in a typical black tea infusion. Fifty years ago the term thearubigins was first introduced and to date the chemical nature of the thearubigins remains largely unresolved, if not mysterious... | ['Camellia sinensis', 'Catechin', 'Fourier Analysis', 'Mass Spectrometry', 'Oxidation-Reduction', 'Phenols', 'Polyphenols', 'Tea'] | 21,072,794 | [['B01.650.940.800.575.912.250.341.998.500.500'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['E05.196.566'], ['G02.700', 'G03.295.531'], ['D02.455.426.559.389.657'], ['D02.455.426.559.389.657.715', 'D0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Relative sialylation and fucosylation of synovial and plasma fibronectins in relation to the progression and activity of rheumatoid arthritis. | The expressions of terminal sugars in synovial and plasma fibronectins were studied in relation to rheumatoid arthritis (RA) progression defined according to the early, established and late radiological changes in the patients' hands. The relative amounts of sialic acid and fucose were analyzed by lectin-ELISA using ap... | ['Adult', 'Aged', 'Arthritis, Rheumatoid', 'Carbohydrates', 'Case-Control Studies', 'Disease Progression', 'Female', 'Fibronectins', 'Fucose', 'Gene Expression Regulation', 'Humans', 'Lectins', 'Male', 'Middle Aged', 'Models, Biological', 'Sialic Acids', 'Synovial Fluid'] | 17,610,063 | [['M01.060.116'], ['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D09'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.291.656'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['D09.25... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Possible mechanism of generation of nitrite and non-thiolate nitroso compounds in blood plasma during inflammatory processes. | Generation of nitrite (NO2?) and non-thiolate nitroso compounds in human blood during leukocyte activation mainly occurred due to destruction of NO donors in the plasma, but not due to intensification of NO synthesis. We proposed a mechanism of production of nitrite and non-thiolate nitroso compounds in the blood durin... | ['Cells, Cultured', 'Humans', 'Kinetics', 'Leukocytes', 'Nitric Oxide', 'Nitrites', 'Nitroso Compounds', 'Zymosan'] | 25,110,088 | [['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['D01.248.497.158.635', 'D01.625.600.600', 'D02.633'], ['D02.654'], ['D09.698.365.089.750']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The clinical efficacy of augmentin (amoxicillin/clavulanate) in treating inflammatory diseases of the urogenital organs]. | Augmentin (amoxycillin/clavulanate) was used in the treatment of 88 patients with mild and moderate infections of the urogenital organs. The drug was administered in a single dose of 375 mg thrice daily for 6 to 12 days. The renal function in 62 patients (70.5 per cent) was normal and in 26 patients (29.5 per cent) the... | ['Acute Disease', 'Adult', 'Aged', 'Amoxicillin-Potassium Clavulanate Combination', 'Anti-Bacterial Agents', 'Chronic Disease', 'Drug Therapy, Combination', 'Humans', 'Inflammation', 'Male', 'Male Urogenital Diseases', 'Middle Aged'] | 10,768,059 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['D02.065.589.099.374.160.060', 'D02.065.589.099.750.750.050.050.060', 'D02.886.108.750.750.050.050.060', 'D03.633.100.300.374.160.060', 'D03.633.100.300.750.750.050.050.500', 'D26.310.102'], ['D27.505.954.122.085'], ['C23.550.291.500'], ['E02.319.310'], ['B01... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Urinary bladder matrix for the treatment of recalcitrant nonhealing radiation wounds. | Chronic wounds in previously radiated tissue are challenging to treat. In this article, the authors describe 3 such wounds that failed to heal despite multiple treatments with traditional wound healing methods. Treatment with porcine urinary bladder matrix, an extracellular matrix material, was initiated to facilitate ... | ['Aged', 'Animals', 'Bandages, Hydrocolloid', 'Chronic Disease', 'Extracellular Matrix', 'Female', 'Humans', 'Male', 'Middle Aged', 'Radiation Injuries', 'Radiotherapy', 'Skin Ulcer', 'Swine', 'Urinary Bladder'] | 24,045,565 | [['M01.060.116.100'], ['B01.050'], ['E07.101.074'], ['C23.550.291.500'], ['A11.284.295.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C26.733', 'G01.750.748.500', 'N06.850.460.350.850.500', 'N06.850.810.300.360'], ['E02.815'], ['C17.800.893'], ['B01.050.150.900.649.313.500.880'], ['A05.8... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Noninvasive evaluation of the swollen extremity: experiences with 190 lymphoscintigraphic examinations. | Lymphoscintigraphy (LS), performed with technetium 99m-labeled antimony trisulfide colloid (Cadema Medical Products, Inc., Middletown, N.Y.), was used as a noninvasive diagnostic examination to evaluate the lymphatic circulation in 190 extremities of 115 patients. Forty-six patients had primary lymphedema, 48 had secon... | ['Adolescent', 'Adult', 'Aged', 'Antimony', 'Arm', 'Child', 'Chronic Disease', 'Colloids', 'Diagnosis, Differential', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Leg', 'Lymphatic System', 'Lymphedema', 'Lymphoscintigraphy', 'Male', 'Middle Aged', 'Postoperative Period', 'Technetium', 'Technetium Compounds'] | 2,724,456 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D01.268.513.124', 'D01.268.556.050', 'D01.552.544.050'], ['A01.378.800.075'], ['M01.060.406'], ['C23.550.291.500'], ['D20.280', 'D26.255.165'], ['E01.171'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['A... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Release and modulation of release of serotonin in rabbit superior colliculus. | The release of previously incorporated [3H]serotonin and its presynaptic modulation were studied in slices of rabbit superior colliculus. Electrical stimulation at frequencies of 0.017-3 Hz greatly increased the outflow of tritiated compounds; this response was almost abolished by tetrodotoxin and in a low calcium medi... | ['Animals', 'Electric Stimulation', 'Female', 'Male', 'Rabbits', 'Receptors, Adrenergic, alpha', 'Receptors, Cholinergic', 'Receptors, Opioid', 'Receptors, Serotonin', 'Serotonin', 'Superior Colliculi', 'Tetrodotoxin'] | 2,555,733 | [['B01.050'], ['E05.723.402'], ['B01.050.150.900.649.313.968.700'], ['D12.776.543.750.670.300.300.300', 'D12.776.543.750.695.150.300.300', 'D12.776.543.750.720.330.300.300'], ['D12.776.543.750.720.360'], ['D12.776.543.750.695.620', 'D12.776.543.750.720.600.610', 'D12.776.543.750.750.555.610'], ['D12.776.543.750.670.800... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metastatic bone involvement in gynecological malignancies. | 4 patients in whom ante mortem diagnosis of bone metastases was made, suffering from primary carcinoma of endometrium, cervix, ovary and vulva, respectively, are herein presented. The different routes of spread of these tumors, as well as a review of the incidence of bone metastases in gynecological malignancies are di... | ['Adult', 'Aged', 'Bone Neoplasms', 'Female', 'Genital Neoplasms, Female', 'Humans', 'Middle Aged', 'Neoplasm Metastasis', 'Ovarian Neoplasms', 'Uterine Cervical Neoplasms', 'Uterine Neoplasms', 'Vulvar Neoplasms'] | 740,895 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.149', 'C05.116.231'], ['C04.588.945.418', 'C13.351.937.418'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.650', 'C23.550.727.650'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.630.705']... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Organisational and legal issues of medical rehabilitation for patients with occupational diseases caused by dust]. | The study based on Rehabilitation Center No 2 in Rostov region covered 100 male patients with dust obstructive bronchitis. The authors considered organisational and legal problems of medical rehabilitation for patients with occupational diseases caused by dust. The authors also specified and suggested stages of individ... | ['Air Pollutants, Occupational', 'Bronchitis', 'Dust', 'Government Regulation', 'Humans', 'Male', 'Occupational Diseases', 'Occupational Health', 'Program Evaluation', 'Quality of Health Care', 'Rehabilitation', 'Rehabilitation Centers', 'Russia'] | 22,180,968 | [['D27.888.284.101.268'], ['C01.748.099', 'C08.127.446', 'C08.381.495.146', 'C08.730.099'], ['D20.633.222'], ['I01.880.604.394', 'N03.706.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C24'], ['N01.400.525'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['N04.761', 'N05.715'], ['E02.760.169.063.500', '... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
The consequence of "doing nothing": Family caregiving for Alzheimer's disease as non-action in the US. | This article adopts a discursive approach in order to examine how dominant US discourses shape both public and personal understandings of the caregiving work that families do, specifically in the context of Alzheimer's disease (AD). Family caregivers are an essential, increasingly recognized piece of the US health care... | ['Adult', 'Aged', 'Alzheimer Disease', 'Attitude to Health', 'Caregivers', 'Family Relations', 'Female', 'Humans', 'Male', 'Medicalization', 'Middle Aged', 'United States'] | 29,222,996 | [['M01.060.116'], ['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['F01.100.150', 'N05.300.150'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['F01.829.263.370', 'I01.880.853.150.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.853.250'], ['M01.060.116.630'], ['Z0... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Capsule endoscopy in a network cooperation: assessment of the experience in 822 patients. | INTRODUCTION: Capsule endoscopy (CE) is firmly established as a standard procedure in the diagnostic algorithm of occult or obscure gastrointestinal bleeding and Crohn's disease. Despite its excellent diagnostic yield, missing expertise, reading time and financial expenditure limit an area-wide availability. A multicen... | ['Abdominal Pain', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Angiodysplasia', 'Capsule Endoscopes', 'Capsule Endoscopy', 'Cooperative Behavior', 'Cost Savings', 'Crohn Disease', 'Duodenal Neoplasms', 'Female', 'Gastrointestinal Diseases', 'Gastrointestinal Hemorrhage', 'Gastrointestinal Transit', 'Humans', '... | 23,834,066 | [['C23.888.592.612.054', 'C23.888.821.030'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.075'], ['E07.230.220.260.140'], ['E01.370.388.250.250.250.140'], ['F01.145.813.115'], ['N03.219.151.160.200'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['C04.588.274.476.411.445'... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Abdominal decompression - should this obstetric method be employed in future too? (author's transl)]. | Heyns developed a method to produce decompression in the abdomen of pregnant women. He stated that the method was recommended to promote analgesia during the period of dilatation and to shorten the delivery period. Since enhanced blood supply of the placenta was expected also, the method was stated to be useful in gest... | ['Blood Pressure', 'Decompression', 'Female', 'Hemodynamics', 'Humans', 'Infant, Newborn', 'Intelligence', 'Labor, Obstetric', 'Lower Body Negative Pressure', 'Maternal-Fetal Exchange', 'Pre-Eclampsia', 'Pregnancy'] | 7,198,335 | [['E01.370.600.875.249', 'G09.330.380.076'], ['E02.278', 'G01.374.715.250'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['F01.752.543'], ['G08.686.784.769.326'], ['E02.278.500'], ['G08.686.784.769.455'], ['C13.703.395.249'], ['G08.686.784.769']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
No Association Between Risk of Anterior Cruciate Ligament Rupture and Selected Candidate Collagen Gene Variants in Female Elite Athletes From High-Risk Team Sports. | BACKGROUND: Several single-nucleotide variants (SNVs) in collagen genes have been reported as predisposing factors for anterior cruciate ligament (ACL) tears. However, the evidence is conflicting and does not support a clear association between genetic variants and risk of ACL ruptures.PURPOSE: To assess the associatio... | ['Adolescent', 'Adult', 'Anterior Cruciate Ligament Injuries', 'Athletes', 'Athletic Injuries', 'Collagen', 'Female', 'Finland', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Norway', 'Polymorphism, Single Nucleotide', 'Prospective Studies', 'Risk Factors', 'Rupture', 'Young Adult'] | 30,485,117 | [['M01.060.057'], ['M01.060.116'], ['C26.558.554.213'], ['M01.072'], ['C26.115'], ['D05.750.078.280', 'D12.776.860.300.250'], ['Z01.542.816.186'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.816.374'], ['G05.365.795.598'], ['E05.318.372.500.750.625', '... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Communication speaks volumes. | As a learning disability nursing student, it became apparent during formal and informal learning that those studying adult nursing had misconceptions about nursing people with a learning disability. | ['Communication', 'Humans', 'Social Media', 'Students, Nursing', 'United Kingdom'] | 27,440,359 | [['F01.145.209', 'L01.143'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.178.751', 'L01.224.230.110.500.750'], ['M01.848.769.685'], ['Z01.542.363']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Antiproliferative activity and apoptosis inducing effects of nitric oxide donating derivatives of evodiamine. | The first series of nitric oxide donating derivatives of evodiamine were designed and prepared. NO releasing ability of all target derivatives was evaluated in BGC-823, Bel-7402 and L-02 cells. The cytotoxicity was evaluated against three human tumor cell lines (Bel-7402, A549 and BGC-823) and normal human liver cells ... | ['Antineoplastic Agents', 'Apoptosis', 'Blotting, Western', 'Cell Cycle', 'Cell Line', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Humans', 'Inhibitory Concentration 50', 'Molecular Structure', 'Nitric Oxide', 'Quinazolines'] | 27,178,387 | [['D27.505.954.248'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.144'], ['A11.251.210'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metaphycus macadamiae (Hymenoptera: Encyrtidae) - a biological control agent of macadamia felted coccid Acanthococcus ironsidei (Hemiptera: Eriococcidae) in Hawaii. | A new species of encyrtid wasp, Metaphycus macadamiae Polaszek & Noyes sp. n., (Hymenoptera: Encyrtidae: Encyrtinae) is described as a solitary endoparasitoid of the invasive macadamia felted coccid, Acanthococcus ironsidei (Hemiptera: Eriococcidae) in Hawaii. This parasitoid is native to Australia, and the species des... | ['Animals', 'Australia', 'Biological Phenomena', 'Hawaii', 'Hemiptera', 'Hymenoptera', 'Macadamia', 'New South Wales', 'Pest Control, Biological', 'South Africa', 'Wasps'] | 32,267,857 | [['B01.050'], ['Z01.639.100', 'Z01.678.100.373'], ['G16'], ['Z01.107.567.875.580.375', 'Z01.639.760.815.482'], ['B01.050.500.131.617.412'], ['B01.050.500.131.617.720.500.500.875'], ['B01.650.940.800.575.912.250.831.500'], ['Z01.639.100.750', 'Z01.678.100.373.750'], ['N06.850.780.200.650.650'], ['Z01.058.290.175.735'], ... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Disruption by interferon-alpha of an autocrine interleukin-6 growth loop in IL-6-dependent U266 myeloma cells by homologous and heterologous down-regulation of the IL-6 receptor alpha- and beta-chains. | IL-6 is an autocrine growth factor for U266 myeloma cells and their growth is inhibited by IFN-alpha or IL-6 mAb. We asked, therefore, whether IFN-alpha-induced growth inhibition involved IL-6. IFN-alpha and mAb against IL-6, the IL-6R alpha-(gp80) or beta-chain (gp130) potently inhibited U266 cells. Remarkably, this e... | ['Affinity Labels', 'Cell Division', 'Cross-Linking Reagents', 'Cytokines', 'Dose-Response Relationship, Drug', 'Down-Regulation', 'Humans', 'Interferon-alpha', 'Interleukin-6', 'Multiple Myeloma', 'Receptors, Interleukin', 'Receptors, Interleukin-6', 'Tumor Cells, Cultured'] | 7,989,587 | [['D27.720.470.410.080'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D27.720.470.410.210'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G07.690.773.875', 'G07.690.936.500'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sleep-Wake Concordance in Couples Is Inversely Associated With Cardiovascular Disease Risk Markers. | Aim: To determine whether interdependence in couples' sleep (sleep-wake concordance i.e., whether couples are awake or asleep at the same time throughout the night) is associated with two markers of cardiovascular disease (CVD) risk, ambulatory blood pressure (BP) and systemic inflammation.Methods: This community-based... | ['Actigraphy', 'Adolescent', 'Adult', 'Biomarkers', 'Blood Pressure', 'Blood Pressure Monitoring, Ambulatory', 'C-Reactive Protein', 'Cardiovascular Diseases', 'Cross-Sectional Studies', 'Female', 'Humans', 'Inflammation', 'Male', 'Middle Aged', 'Risk Factors', 'Sleep', 'Spouses', 'Young Adult'] | 28,364,457 | [['E01.370.520.049', 'E05.003.500'], ['M01.060.057'], ['M01.060.116'], ['D23.101'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140.100', 'E01.370.520.500.100'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['C14'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Promoter length polymorphism in UGT1A1 and the risk of sporadic colorectal cancer. | Uridine diphosphoglucuronate glucuronosyltransferase 1A1 (UGT1A1) is the key hepatic detoxification enzyme involved in the biotransformation of many carcinogens implicated in the development of colon, breast, and prostate cancers in humans. A polymorphism in the UGT1A1 promoter containing a TA-repeat element [(TA)5-8TA... | ['Aged', 'Aged, 80 and over', 'Alleles', 'Case-Control Studies', 'Colorectal Neoplasms', 'Female', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Genotype', 'Glucuronosyltransferase', 'Greece', 'Humans', 'Male', 'Middle Aged', 'Polymorphism, Genetic', 'Promoter Regions, Genetic', 'Risk Factors'] | 22,559,977 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G05.360.340.024.340.030'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E05.393.385'], ['C2... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Is the high-risk strategy to prevent cardiovascular disease equitable? A pharmacoepidemiological cohort study. | BACKGROUND: Statins are increasingly prescribed to prevent cardiovascular disease (CVD) in asymptomatic individuals. Yet, it is unknown whether those at higher CVD risk - i.e. individuals in lower socio-economic position (SEP) - are adequately reached by this high-risk strategy. We aimed to examine whether the Danish i... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cardiovascular Diseases', 'Cohort Studies', 'Denmark', 'Female', 'Healthcare Disparities', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Male', 'Middle Aged', 'Pharmacoepidemiology', 'Risk Assessment', 'Social Class'] | 22,863,326 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['Z01.542.816.124'], ['N04.590.374.380', 'N05.300.493'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.186.071.202.370', 'D27.505.519.389.370', 'D27.50... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Accounting for natural tension in the mechanical testing of human skin. | A low-pressure suction device has previously been used to obtain quantitative information on the mechanical properties of human skin. Reducing the raw data from this technique was complicated by the fact that the skin is already biaxially loaded in the natural state and a rational basis on which to compare results obta... | ['Adult', 'Age Factors', 'Biomechanical Phenomena', 'Humans', 'Male', 'Middle Aged', 'Skin Physiological Phenomena', 'Stress, Mechanical', 'Sunlight'] | 894,069 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G13.750'], ['G01.374.835'], ['G01.358.500.505.650.836', 'G01.750.250.650.836', 'G01.750.770.578.836', 'G16.500.275.063.725.525', 'G16.500.750.775.525', 'N06.2... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Rapid sperm capture: high-throughput flagellar waveform analysis. | STUDY QUESTION: Can flagellar analyses be scaled up to provide automated tracking of motile sperm, and does knowledge of the flagellar waveform provide new insight not provided by routine head tracking?SUMMARY ANSWER: High-throughput flagellar waveform tracking and analysis enable measurement of experimentally intracta... | ['Andrology', 'Biomechanical Phenomena', 'Cell Tracking', 'Humans', 'Hydrodynamics', 'Male', 'Software', 'Sperm Motility', 'Sperm Tail'] | 31,170,729 | [['H02.403.763.500'], ['G01.154.090', 'G01.374.089'], ['E01.370.225.500.373', 'E01.370.350.557.500', 'E05.200.500.373', 'E05.242.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.342'], ['L01.224.900'], ['E01.370.225.992.812', 'E05.200.992.812', 'G04.198.750'], ['A05.360.490.890.840', 'A11.284.180.290.835',... | ['Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Synthesis of proline-based diketopiperazine scaffolds. | A number of natural products with interesting biological properties are based on a diketopiperazine scaffold. In this context, we have developed a diversity oriented and efficient synthetic strategy to highly functionalized proline-based diketopiperazines. In this paper we describe the stereoselective synthesis of vari... | ['Biological Products', 'Combinatorial Chemistry Techniques', 'Piperazine', 'Piperazines', 'Proline', 'Small Molecule Libraries', 'Stereoisomerism'] | 19,391,606 | [['D20.215'], ['E05.197.312', 'J01.897.836.249.249'], ['D03.383.606.768'], ['D03.383.606'], ['D12.125.072.401.623'], ['D27.720.470.765'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Ruthenium-106 versus iodine-125 plaque brachytherapy of 571 choroidal melanomas with a thickness of ?5.5 mm. | BACKGROUND: Episcleral brachytherapy is the most common eye-preserving treatment for medium-sized choroidal melanomas. ã-emitting iodine-125 (125I) and â-emitting ruthenium-106 (106Ru) are widely used. The latter is however generally reserved for thinner tumours (<6 mm). In this study, we compare ocular and patient sur... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Brachytherapy', 'Choroid Neoplasms', 'Eye Enucleation', 'Female', 'Humans', 'Iodine Radioisotopes', 'Kaplan-Meier Estimate', 'Male', 'Melanoma', 'Middle Aged', 'Proportional Hazards Models', 'Radiotherapy Dosage', 'Retrospective Studies', 'Ruthenium Radioisotopes', ... | 30,910,871 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.815.150'], ['C04.588.364.978.223', 'C11.319.494.198', 'C11.941.160.238', 'C11.941.855.198'], ['E04.540.429'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['E05.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
31P-NMR spectroscopic investigations and mitochondrial studies on the cardioprotective efficiency of 2-mercaptopropionylglycine. | Contents of high energy phosphates in the isolated perfused rat heart were followed during ischemia and reperfusion using 31P NMR spectroscopy. Application of 2-mercaptopropionylglycine resulted in significantly higher content of ATP in the reperfusion phase whereas during ischemia no differences between control and th... | ['Adenosine Triphosphatases', 'Adenosine Triphosphate', 'Amino Acids, Sulfur', 'Animals', 'Coronary Disease', 'Female', 'Magnetic Resonance Spectroscopy', 'Mitochondria, Heart', 'Myocardium', 'Oxygen Consumption', 'Phosphocreatine', 'Rats', 'Rats, Inbred Strains', 'Tiopronin'] | 2,947,579 | [['D08.811.277.040.025'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D02.886.030', 'D12.125.166'], ['B01.050'], ['C14.280.647.250', 'C14.907.585.250'], ['E05.196.867.519'], ['A11.284.430.214.190.875.564.627.603', 'A11.284.835.626.627.603'], ['A02.633.580', 'A07.541.704', 'A10.690.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A novel allele HLA-A*11:152 was identified by sequence-based typing in a Chinese individual. | HLA-A*11:152 differs from A*11:01:01 by a single nucleotide at position 266 in Exon 2. | ['Alleles', 'Amino Acid Substitution', 'Asian Continental Ancestry Group', 'Base Sequence', 'Exons', 'Gene Expression', 'Genetic Loci', 'HLA-A11 Antigen', 'Hematopoietic Stem Cell Transplantation', 'Hematopoietic Stem Cells', 'Histocompatibility Testing', 'Humans', 'Molecular Sequence Data', 'Polymorphism, Single Nucle... | 26,814,407 | [['G05.360.340.024.340.030'], ['E05.393.420.601.035', 'G05.558.109'], ['M01.686.508.200'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.360.340.024.340.137.232'], ['G05.297'], ['G05.360.340.024.380'], ['D12.776.395.550.489.400.110', 'D12.776.543.550.439.400.110', 'D23.050.301.500.100.400.110', 'D23.... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Effect of homoserine on growth of Mycobacterium smegmatis: inhibition of glutamate transport by homoserine. | Homoserine strongly inhibited growth of Mycobacterium smegmatis in medium containing glutamate as the sole source of nitrogen but was without effect when asparagine, alanine or glutamine was the sole nitrogen source. It was readily taken up by glutamate-grown cells, reaching an intracellular concentration of over 20 mM... | ['Biological Transport', 'Glutamates', 'Glutamic Acid', 'Homoserine', 'Mycobacterium'] | 2,896,760 | [['G03.143'], ['D12.125.067.625', 'D12.125.119.409'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['D12.125.526'], ['B03.510.024.962.500', 'B03.510.460.400.410.552.552']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
AsMA Medical Guidelines for Air Travel: Airline Special Services. | INTRODUCTION: Medical Guidelines for Airline Travel provide information that enables healthcare providers to properly advise patients who plan to travel by air. Treating physicians should advise patients in need of special services to contact the airline well before travel to find out if the required services will be a... | ['Aerospace Medicine', 'Air Travel', 'Aircraft', 'Guidelines as Topic', 'Humans', 'Oxygen Inhalation Therapy', 'Travel Medicine'] | 26,102,149 | [['H02.403.029'], ['I03.883.209'], ['J01.937.285.100'], ['N04.761.700.350', 'N05.700.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.880.690'], ['H02.403.850']] | ['Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 |
Increased Langerhans cell accumulation after mycobacterial stimuli. | AIMS: To evaluate the role of Langerhans cells (LCs) in the local activation of leprosy lesions. LCs, acting as tolerance inducers and immune stimuli, are dendritic cells recently implicated in cutaneous homeostasis. The role of LCs in the defence against mycobacterial infection remains poorly understood.METHODS AND RE... | ['Antigens, CD1', 'HLA-DR Antigens', 'Humans', 'Intercellular Adhesion Molecule-1', 'Langerhans Cells', 'Leprosy, Lepromatous', 'Mycobacterium leprae', 'Skin'] | 17,927,586 | [['D23.050.301.264.035.100', 'D23.050.301.264.894.080', 'D23.101.100.110.100', 'D23.101.100.894.080'], ['D12.776.395.550.509.400.440', 'D12.776.543.550.440.400.440', 'D23.050.301.500.400.400.440', 'D23.050.301.500.450.400.440', 'D23.050.705.552.410.400.440', 'D23.050.705.552.450.400.440'], ['B01.050.150.900.649.313.988... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Novel triple neurokinin receptor antagonist CS-003 strongly inhibits neurokinin related responses. | Neurokinins are known to induce neurogenic inflammation related to respiratory diseases, though there is little information on triple neurokinin receptor antagonists. The pharmacological properties of the novel triple neurokinin 1, 2 and 3 receptor antagonist [1-(2-[(2R)-(3,4-dichlorophenyl)-4-(3,4,5-trimethoxybenzoyl)... | ['Animals', 'Bronchi', 'COS Cells', 'Capillary Permeability', 'Capsaicin', 'Chlorocebus aethiops', 'Citric Acid', 'Cough', 'Cyclic S-Oxides', 'Dipeptides', 'Dose-Response Relationship, Drug', 'Guinea Pigs', 'Humans', 'In Vitro Techniques', 'Indoles', 'Inositol Phosphates', 'Male', 'Molecular Sequence Data', 'Morpholine... | 18,353,309 | [['B01.050'], ['A04.411.125'], ['A11.251.210.172.500', 'A11.329.228.220'], ['G03.143.330', 'G09.330.165'], ['D02.065.690.500', 'D02.455.326.271.690.222', 'D02.455.426.559.389.657.166.099', 'D03.132.760.200', 'D10.251.355.325.190'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D02.241.081.901.434.249'], ['... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Is synovectomy a sure treatment procedure for synovial osteochondromatosis?]. | In recent literature synovectomy is recommended for treating osteochondromatosis. In the case of a 25-year-old woman with an affected knee joint, who was treated with synovectomy, the authors observed recurrence 5 years later. Ten years after the operation a severe osteoarthritis had developed. Our experience suggests ... | ['Adult', 'Female', 'Humans', 'Joint Diseases', 'Joint Loose Bodies', 'Knee Joint', 'Osteochondritis', 'Postoperative Complications', 'Prognosis', 'Synovectomy', 'Synovial Membrane'] | 3,407,311 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550'], ['C05.550.535'], ['A02.835.583.475'], ['C05.116.791', 'C05.182.520', 'C17.300.182.520'], ['C23.550.767'], ['E01.789'], ['E04.555.640'], ['A02.835.583.443.800']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Q fever and pregnancy: disease, prevention, and strain specificity. | The link between fetal morbidity and Q fever and the necessity of long-term antibiotics for Coxiella burnetii infection during pregnancy have been recently questioned in the Netherlands, where the clone responsible for the Q fever outbreak harbors the QpH1 plasmid. In this context, we assessed pregnancy outcomes accord... | ['Abortion, Septic', 'Adult', 'Anti-Bacterial Agents', 'Coxiella burnetii', 'DNA, Bacterial', 'Female', 'Fetal Mortality', 'France', 'Genotype', 'Humans', 'Plasmids', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Q Fever', 'Sequence Analysis, DNA', 'Trimethoprim, Sulfamethoxazole Drug Combination', 'Virulence'] | 23,052,984 | [['C01.674.173', 'C13.703.039.256', 'C13.703.700.173'], ['M01.060.116'], ['D27.505.954.122.085'], ['B03.440.400.425.297.150.100', 'B03.660.250.132.150.100'], ['D13.444.308.212'], ['E05.318.308.985.550.362', 'N01.224.935.698.300', 'N06.850.505.400.975.550.362', 'N06.850.520.308.985.550.362'], ['Z01.542.286'], ['G05.380'... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A novel induced-fit reaction mechanism of asymmetric hot dog thioesterase PAAI. | Hot dog fold proteins sharing the characteristic "hot dog" fold are known to involve certain coenzyme A binding enzymes with various oligomeric states. In order to elucidate the oligomerization-function relationship of the hot dog fold proteins, crystal structures of the phenylacetate degradation protein PaaI from Ther... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Binding Sites', 'Crystallography, X-Ray', 'Humans', 'Ligands', 'Models, Molecular', 'Molecular Sequence Data', 'Molecular Structure', 'Palmitoyl-CoA Hydrolase', 'Protein Folding', 'Protein Structure, Tertiary', 'Sequence Alignment', 'Thermus thermophilus'] | 16,061,252 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.120'], ['E05.196.309.742.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.480'], ['E05.599.595'], ['L01.453.245.667'], ['G02.111.570', 'G02.466'], ['D08.811.277.352.897.700'], ['G01.154.651', 'G02.111.688'], ['G02.111.570.8... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Dynamics of electrophysiological parameters of the heart in hypertensive patients depending on a 24-h profile of arterial pressure, left ventricular geometry and metabolic disorders]. | AIM: To examine conduction system and repolarization in the ventricles and heart rate variability in hypertensive patients with consideration of 24-h blood pressure profile, left ventricular (LV) geometry and metabolic disorders.MATERIAL AND METHODS: 24-h monitoring of blood pressure, diagnostic transesophageal electro... | ['Adult', 'Blood Pressure', 'Blood Pressure Monitoring, Ambulatory', 'Disease Progression', 'Echocardiography', 'Electrocardiography', 'Female', 'Heart Ventricles', 'Humans', 'Hypertension', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Prognosis', 'Sinoatrial Node', 'Ventricular Remodeling'] | 17,076,218 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140.100', 'E01.370.520.500.100'], ['C23.550.291.656'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.90... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Adaptation reactions of the body in fractures and fracture-dislocations of the bones of the foot]. | Having analysed the results of studies of the morphological composition of blood in 136 patients the author established that adaptation reactions (e. g. stress, training, activation) in their identification according to the hematologic values reflect the clinical course of the posttraumatic processes and may be used fo... | ['Adaptation, Physiological', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Foot Injuries', 'Fractures, Bone', 'Humans', 'Joint Dislocations', 'Male', 'Middle Aged', 'Prognosis'] | 2,571,964 | [['G07.025', 'G16.012.500'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C26.558.300'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['M01.060.116.630'], ['E01.789']] | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Delayed prenatal care and the risk of low birth weight delivery. | To determine if the timing of prenatal care is associated with low birth weight delivery after adjusting for sociodemographic and behavioral risk factors, we performed a retrospective cross-sectional study of singleton births to white (2,945,595) or African-American (552,068) women in the United States in 1996. When ad... | ['Adult', 'African Americans', 'Alcohol Drinking', 'Birth Certificates', 'Cross-Sectional Studies', 'Educational Status', 'European Continental Ancestry Group', 'Female', 'Humans', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Patient Acceptance of Health Care', 'Pregnancy', 'Pregnant Women', 'Prenatal Care', 'Regres... | 12,713,070 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['F01.145.317.269'], ['E05.318.308.940.250', 'L01.399.250.900.250', 'N04.452.859.132', 'N05.715.360.300.715.175', 'N06.850.520.308.940.250'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N01.824.196'], ['M01.686.508.400'],... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
[Experience with postmortem chromosome analysis]. | Over the years 1986-1988 necroptic material, collected according to 5 established indication groups, was cultured. A total of 202 samples of necroptic material cultured and 122 of these samples were analyzed cytogenetically. Seventeen pathologic karyotypes were diagnosed in the material, namely 7 cases of Down's syndro... | ['Autopsy', 'Chromosome Aberrations', 'Chromosome Disorders', 'Culture Techniques', 'Humans', 'Infant', 'Infant, Newborn', 'Karyotyping'] | 2,224,551 | [['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['C23.550.210', 'G05.365.590.175'], ['C16.131.260', 'C16.320.180'], ['E05.481.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Granulocyte-macrophage colony stimulating factor blockade promotes ccr9(+) lymphocyte expansion in Nod2 deficient mice. | BACKGROUND: Ileal involvement in Crohn's disease (CD) is associated with NOD2 mutations and granulocyte-macrophage colony stimulating factor autoantibodies (GM-CSF Ab), and GM-CSF blockade promotes ileitis in Nod2/Card15-deficient (C15KO) mice. RALDH2-expressing dendritic cells (DC) and IL-4 promote CCR9 imprinting and... | ['Aldehyde Oxidoreductases', 'Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Chemokines, CC', 'Child', 'Crohn Disease', 'Dendritic Cells', 'Disease Models, Animal', 'Female', 'Flow Cytometry', 'Granulocyte-Macrophage Colony-Stimulating Factor', 'Humans', 'Ileitis', 'Immunoenzyme Techniques', 'Interleukin-10', 'L... | 21,381,154 | [['D08.811.682.657.163'], ['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D12.644.276.374.200.110', 'D12.776.467.374.200.110', 'D23.125.300.110', 'D23.469.200.110', 'D23.529.374.200.110'], ['M01.060.406'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['A11.066.270', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Homozygous frameshift mutations in FAT1 cause a syndrome characterized by colobomatous-microphthalmia, ptosis, nephropathy and syndactyly. | A failure in optic fissure fusion during development can lead to blinding malformations of the eye. Here, we report a syndrome characterized by facial dysmorphism, colobomatous microphthalmia, ptosis and syndactyly with or without nephropathy, associated with homozygous frameshift mutations in FAT1. We show that Fat1 k... | ['Adolescent', 'Adult', 'Animals', 'Blepharoptosis', 'Cadherins', 'Cells, Cultured', 'Child', 'Child, Preschool', 'Coloboma', 'DNA Mutational Analysis', 'Embryo, Mammalian', 'Eye', 'Facial Bones', 'Female', 'Frameshift Mutation', 'Humans', 'Intercellular Junctions', 'Kidney Diseases', 'Male', 'Mice', 'Mice, Inbred C57B... | 30,862,798 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['C11.338.204'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['A11.251'], ['M01.060.406'], ['M01.060.406.448'], ['C11.250.110', 'C11.270.147', 'C16.131.384.282'], ['E05.393.760.700.300'], ['A16.254'], ['A01.456.505.420', 'A09.371'], ['A0... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Primary transcutaneous lower blepharoplasty with routine lateral canthal support: a comprehensive 10-year review. | BACKGROUND: Rejuvenation of the lower eyelid often requires tightening of excess skin and muscle and removal or transposition of orbital fat. Although transcutaneous lower blepharoplasty can accomplish these aesthetic demands, it has been associated with an increased risk of lower lid malposition. Routine lateral canth... | ['Adult', 'Aged', 'Blepharoplasty', 'Eyelids', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies'] | 18,176,227 | [['M01.060.116'], ['M01.060.116.100'], ['E04.540.104', 'E04.680.275.090'], ['A01.456.505.420.504', 'A09.371.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Serial MRI to determine the effect of dexamethasone on the cerebral pathology of tuberculous meningitis: an observational study. | BACKGROUND: Adjunctive dexamethasone increases survival from tuberculous meningitis, but the underlying mechanism is unclear. We aimed to determine the effect of dexamethasone on cerebral MRI changes and their association with intracerebral inflammatory responses and clinical outcome in adults treated for tuberculous m... | ['Adolescent', 'Adult', 'Aged', 'Anti-Inflammatory Agents', 'Antitubercular Agents', 'Brain', 'Cerebral Infarction', 'Cohort Studies', 'Dexamethasone', 'Double-Blind Method', 'Female', 'Humans', 'Hydrocephalus', 'Inflammation', 'Inflammation Mediators', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Treatment Ou... | 17,303,529 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.158'], ['D27.505.954.122.085.255'], ['A08.186.211'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['E05.318.372.500.750', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Manganese decreases glutamate uptake in cultured astrocytes. | Recent data have shown an accumulation of manganese in the basal ganglia in patients with chronic hepatic encephalopathy (HE). Astrocytes and ammonia are critically involved in the pathogenesis of HE, and we have recently demonstrated that ammonia decreases glutamate uptake in cultured astrocytes. Since failure by astr... | ['Adenosine Triphosphate', 'Ammonia', 'Animals', 'Aspartic Acid', 'Astrocytes', 'Biological Transport', 'Cells, Cultured', 'Drug Combinations', 'Glutamic Acid', 'Kinetics', 'Manganese', 'Rats', 'Sucrose'] | 9,357,008 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D01.362.075', 'D01.625.050'], ['B01.050'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['A08.637.200', 'A11.650.200'], ['G03.143'], ['A11.251'], ['D26.310'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Chinese Morningness-Eveningness-Stability-Scale improved (MESSi): validity, reliability, and associations with sleep quality, personality, affect and life satisfaction. | Individual differences in time of day preference have important correlates. Morningness is associated with greater well-being, while eveningness is associated with more maladaptive behaviors, psychological distress, and disorder. The availability of valid, reliable, questionnaire scales is central to this ongoing resea... | ['Adolescent', 'Adult', 'Affect', 'Circadian Rhythm', 'Female', 'Humans', 'Individuality', 'Male', 'Middle Aged', 'Personal Satisfaction', 'Personality', 'Sleep', 'Surveys and Questionnaires', 'Young Adult'] | 31,179,750 | [['M01.060.057'], ['M01.060.116'], ['F01.470.047'], ['G07.180.562.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.488'], ['M01.060.116.630'], ['F01.145.677'], ['F01.752'], ['F02.830.855', 'G11.561.803'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Minisequencing with acyclonucleoside triphosphates tethered to lanthanide(III) chelates. | Four acyclic nucleoside triphosphates (derivatives of cytosine, thymine, 7-deazaadenine, and 7-deazaguanine) labeled with nonluminescent europium, terbium, dysprosium, and samarium chelates of 2,2',2'',2'''-[[4-(4-isothiocyanatophenyl)ethyl]pyridine-2,6-diyl]bis(methylenenitrilo)]tetrakis(acetic acid) were applied to m... | ['Base Sequence', 'Chelating Agents', 'Cystic Fibrosis Transmembrane Conductance Regulator', 'Genotype', 'Lanthanoid Series Elements', 'Molecular Sequence Data', 'Nucleotides', 'Oligonucleotides', 'Point Mutation', 'Polymerase Chain Reaction', 'Sequence Analysis, DNA', 'Staining and Labeling'] | 18,505,280 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D12.776.157.530.100.304.500', 'D12.776.157.530.400.175.125', 'D12.776.157.530.450.074.500.500.500.500', 'D12.776.543.550.450.175.125', 'D12.776.543.585.100.304.500', 'D12.776.543.585.400.175.125', 'D12.776.543.585.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of antiresorptive agents on osteomyelitis: novel insights into the pathogenesis of osteonecrosis of the jaw. | The effects of antiresorptive agents (e.g., alendronate [Aln], osteoprotegerin [OPG]) on bone infection are unknown. Thus, their effects on implant-associated osteomyelitis (OM) were investigated in mice using PBS (placebo), gentamycin, and etanercept (TNFR:Fc) controls. None of the drugs affected humoral immunity, ang... | ['Animals', 'Biofilms', 'Bone Density Conservation Agents', 'Chronic Disease', 'Cytokines', 'Drug Evaluation, Preclinical', 'Humans', 'Immunity', 'Incidence', 'Jaw Diseases', 'Mice', 'Neovascularization, Physiologic', 'Osteoclasts', 'Osteomyelitis', 'Osteonecrosis', 'Staphylococcal Infections'] | 20,392,222 | [['B01.050'], ['A20.593', 'G06.120'], ['D27.505.696.242'], ['C23.550.291.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['E05.290.750', 'E05.337.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A technique for arthroscopic mattress suture placement. | Many techniques and instrument systems have been developed for performing arthroscopic Bankart repair and arthroscopic rotator cuff repair. These procedures often use multiple simple sutures placed in the repaired tissue. The use of a mattress suture design allows for inversion or eversion of the repaired tissue, great... | ['Arthroscopes', 'Humans', 'Rotator Cuff', 'Rotator Cuff Injuries', 'Surgical Instruments', 'Suture Techniques', 'Sutures'] | 8,280,338 | [['E07.230.220.060', 'E07.858.240.060'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.567.912', 'A02.880.700'], ['C26.761.340', 'C26.803.063', 'C26.874.400'], ['E07.858.700'], ['E04.987.775'], ['E07.858.690.820']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of pyruvate dehydrogenase coenzymes and mitochondrial proteins on the accumulation of [35S]lipoic acid]. | Coenzymes introduced in the ratio, peculiar for pyruvate dehydrogenase complex into the medium containing fresh-isolated mitochondria and oxidation substrate--pyruvate increase accumulation of [35S] lipoate by these organelles. This process is highly stimulated by introducing either the only CoA or a coenzyme mixture (... | ['Animals', 'Coenzymes', 'In Vitro Techniques', 'Male', 'Mitochondria, Liver', 'Multienzyme Complexes', 'Pyruvate Dehydrogenase Complex', 'Rats', 'Thioctic Acid'] | 3,927,544 | [['B01.050'], ['D08.211'], ['E05.481'], ['A11.284.430.214.190.875.564.461', 'A11.284.835.626.461'], ['D05.500.562', 'D08.811.600'], ['D05.500.562.625', 'D08.811.600.741'], ['B01.050.150.900.649.313.992.635.505.700'], ['D02.241.803', 'D02.886.778.827', 'D08.211.906', 'D10.251.941']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spot size reduction in coupling of laser to micromanipulator in laser microsurgery by fiberoptic link. | BACKGROUND AND OBJECTIVE: In coupling laser with micromanipulator through fiberoptics, the resulting diameter of the spot is limited by the laws of geometrical optics, because of the high numerical aperture (N.A.) of fiberoptic radiation. A new method for the reduction of spot size diameter is suggested.STUDY DESIGN/MA... | ['Algorithms', 'Equipment Design', 'Fiber Optic Technology', 'Helium', 'Laser Therapy', 'Lasers', 'Lenses', 'Micromanipulation', 'Microsurgery', 'Neon', 'Surface Properties'] | 7,564,860 | [['G17.035', 'L01.224.050'], ['E05.320'], ['H01.671.617.249'], ['D01.268.613.350', 'D01.362.641.352'], ['E02.594', 'E04.014.520'], ['E07.632.490', 'E07.710.520'], ['E07.632.500'], ['E05.591'], ['E04.494', 'E05.591.580'], ['D01.268.613.600', 'D01.362.641.592'], ['G02.860']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Cancer Screening Patterns Among Current, Former, and Never Smokers in the United States, 2010-2015. | Importance: National guidelines recommend screening for several cancer types, yet screening rates remain below target. To date, cancer screening patterns by smoking status, a major cancer risk factor, are unknown.Objective: To assess cancer screening patterns among individuals who never smoked (never smokers), formerly... | ['Adult', 'Aged', 'Aged, 80 and over', 'Attitude to Health', 'Cross-Sectional Studies', 'Early Detection of Cancer', 'Female', 'Humans', 'Logistic Models', 'Male', 'Mass Screening', 'Middle Aged', 'Risk Factors', 'Smokers', 'United States', 'Young Adult'] | 31,099,863 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.150', 'N05.300.150'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.390.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Stalk domain of the dynamin-like MxA GTPase protein mediates membrane binding and liposome tubulation via the unstructured L4 loop. | The human MxA protein is an interferon-induced large GTPase with antiviral activity against a wide range of viruses, including influenza viruses. Recent structural data demonstrated that MxA oligomerizes into multimeric filamentous or ring-like structures by virtue of its stalk domain. Here, we show that negatively cha... | ['Cryoelectron Microscopy', 'Dynamins', 'GTP-Binding Proteins', 'Guanosine Triphosphate', 'Humans', 'Hydrolysis', 'Membrane Lipids', 'Membranes, Artificial', 'Mutation', 'Myxovirus Resistance Proteins', 'Protein Multimerization', 'Protein Structure, Quaternary', 'Protein Structure, Secondary', 'Protein Structure, Terti... | 21,900,240 | [['E01.370.350.515.402.150', 'E05.595.402.150'], ['D08.811.277.040.330.200', 'D12.776.220.600.450.200', 'D12.776.543.990.400'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['D03.633.100.759.646.454.504', 'D13.695.667.454.504', 'D13.695.827.426.504'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.380'], ['D... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Dispersive liquid-liquid microextraction as a new clean-up procedure for the determination of parabens, perfluorinated compounds, UV filters, biocides, surfactants, and plasticizers in root vegetables. | An analytical method based on ultrasound-assisted extraction and dispersive liquid-liquid microextraction (DLLME) clean-up has been developed and validated for the determination of 31 emerging pollutants in root vegetables. The target compounds were four preservatives, six perfluoroalkyl compounds, six UV filters, two ... | ['Chromatography, Liquid', 'Disinfectants', 'Environmental Pollutants', 'Fluorocarbons', 'Limit of Detection', 'Liquid Phase Microextraction', 'Parabens', 'Plant Roots', 'Plasticizers', 'Sunscreening Agents', 'Surface-Active Agents', 'Tandem Mass Spectrometry', 'Vegetables'] | 29,947,903 | [['E05.196.181.400'], ['D27.505.954.122.425', 'D27.720.274'], ['D27.888.284'], ['D02.455.526.510.435'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['E05.196.155.650.500'], ['D02.241.223.100.300.460', 'D02.241.511.390.460', 'D02.455.426.559.389.127.281.460', 'D02.455.426.559.389.657.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
A high level of thymine replacement by 5-hydroxymethyluracil in nuclear DNA of the primitive dinoflagellate Prorocentrum micans E. | The nuclei of dinoflagellate protists display several distinctive features which make it difficult to assign these organisms as either eukaryotes or prokaryotes. We investigated some physical properties of purified nuclear DNA from the primitive species Prorocentrum micans. Nuclear DNA was separated on a CsCl gradient,... | ['Animals', 'Base Composition', 'Centrifugation, Density Gradient', 'Cytosine', 'DNA', 'Dinoflagellida', 'Guanine', 'Nucleic Acid Denaturation', 'Pentoxyl', 'Thymine', 'Uracil'] | 6,889,504 | [['B01.050'], ['G02.111.080'], ['E05.181.724.336', 'E05.196.941.336'], ['D03.383.742.698.421'], ['D13.444.308'], ['B01.043.214'], ['D03.633.100.759.758.399.454'], ['E05.393.640', 'G02.111.603', 'G05.627'], ['D03.383.742.698.875.700'], ['D03.383.742.698.875.899'], ['D03.383.742.698.875']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regional differences in olfactory epithelial homeostasis in the adult mouse. | The olfactory sensory neurons in the nasal cavity of the adult mouse are organized into a few regions that differ in their molecular properties, as several classes of genes show regional expression. Most renowned is the fact that expression of each of hundreds of different odorant receptor genes is limited to one such ... | ['Aging', 'Animals', 'Basic Helix-Loop-Helix Transcription Factors', 'Bromodeoxyuridine', 'Cell Survival', 'Forkhead Transcription Factors', 'Histones', 'Homeostasis', 'Immunohistochemistry', 'In Situ Hybridization', 'Mice', 'Mice, Inbred C57BL', 'Nerve Tissue Proteins', 'Neurogenesis', 'Neurons', 'Olfactory Mucosa', '... | 19,177,519 | [['G07.345.124'], ['B01.050'], ['D12.776.260.103', 'D12.776.930.125'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['G04.346'], ['D12.776.260.950.249', 'D12.776.930.977.249'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['G07.410'], ['E01.370.225.500.607.512... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Mechanisms and biomarkers of cardiovascular injury induced by phosphodiesterase inhibitor III SK&F 95654 in the spontaneously hypertensive rat. | The cardiovascular injury of the type III selective PDE inhibitor SK&F 95654 was investigated in SHR. Twenty-four hours after a single sc injection of 100 or 200 mg/kg of the drug, rats exhibited cardiomyocyte necrosis and apoptosis, interstitial inflammation, hemorrhage and edema, as well as mesenteric arterial hemorr... | ['Alanine Transaminase', 'Animals', 'Apoptosis', 'Aspartate Aminotransferases', 'Biomarkers', 'Cardiovascular Diseases', 'Cardiovascular System', 'Creatine', 'Endothelial Cells', 'Hippurates', 'Immunohistochemistry', 'Interleukin-6', 'Male', 'Mast Cells', 'Myocytes, Cardiac', 'Phosphodiesterase Inhibitors', 'Pyridazine... | 16,537,294 | [['D08.811.913.477.700.100'], ['B01.050'], ['G04.146.954.035'], ['D08.811.913.477.700.225'], ['D23.101'], ['C14'], ['A07'], ['D02.078.370.280', 'D12.125.373'], ['A11.436.275'], ['D02.065.277.431', 'D02.241.223.100.100.400', 'D02.241.755.360', 'D02.455.426.559.389.127.085.460'], ['E01.370.225.500.607.512', 'E01.370.225.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A clinically relevant orthotopic implantation nude mouse model of human epithelial ovarian cancer--based on consecutive observation. | The aim of this study is to establish an orthotopic implantation nude mouse model of epithelial ovarian cancer (EOC) and observe its biologic features. A human ovarian tumor line SKOV3ipl previously grown subcutaneously was implanted orthotopically as intact tissue into the ovarian capsule of 64 nude mice. Every week e... | ['Animals', 'Cell Line, Tumor', 'Disease Models, Animal', 'Female', 'Humans', 'Mice', 'Mice, Nude', 'Neoplasm Metastasis', 'Neoplasm Transplantation', 'Neoplasms, Experimental', 'Ovarian Neoplasms', 'Survival Rate'] | 16,174,235 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.500'], ['C04.697.650', 'C23.550.727.650'], ['E05.624'], ['C04.619', 'E05.598.50... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Task differentiation, in pathology as well]. | The field of clinical pathology, like other medical professions, is becoming more and more complex, leading to a need for subspecialisation and task differentiation. Whereas the deployment of Physician Assistants is common in other specialties, it is still rare in pathology. Although legal regulations state that histop... | ['Humans', 'Lymph Nodes', 'Pathology, Clinical', 'Physician Assistants', "Physician's Role", 'Task Performance and Analysis', 'Workforce'] | 23,657,104 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.549.400', 'A15.382.520.604.412'], ['H02.403.650.500'], ['M01.526.485.067.740', 'N02.360.067.740'], ['F01.829.316.616.625.600'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600'], ['N04.452.525']] | ['Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
No cost of echolocation for bats in flight. | Echolocation has evolved in relatively few animal species. One constraint may be the high cost of producing pulses, the echoes of which can be detected over useful distances. The energy cost of echolocation in a small (6 g) insectivorous bat, when hanging at rest, was recently measured at 0.067 Joules per pulse, implyi... | ['Animals', 'Chiroptera', 'Echolocation', 'Energy Metabolism', 'Flight, Animal'] | 2,011,191 | [['B01.050'], ['B01.050.150.900.649.313.937'], ['F01.145.113.055.400'], ['G03.295'], ['G11.427.410.568.304', 'G11.427.410.698.416']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells. | We compared bona fide human induced pluripotent stem cells (iPSCs) derived from umbilical cord blood (CB) cells and neonatal keratinocytes (K). As a consequence of both incomplete erasure of tissue-specific methylation and aberrant de novo methylation, CB-iPSCs and K-iPSCs were distinct in genome-wide DNA methylation p... | ['Cell Differentiation', 'Cell Lineage', 'DNA Methylation', 'Epigenesis, Genetic', 'Fetal Blood', 'Gene Expression Regulation', 'Genome, Human', 'Humans', 'Induced Pluripotent Stem Cells', 'Keratinocytes', 'Microarray Analysis'] | 22,119,740 | [['G04.152'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['G05.308.203'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['G05.308'], ['G05.360.340.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessing mobility difficulties for cross-national comparisons: results from the World Health Organization Study on Global AGEing and Adult Health. | OBJECTIVES: To assess the correspondence between self-reported and measured indicators of mobility disability in older adults in six low- and middle-income countries (LMICs).DESIGN: Cross-sectional analysis of Study on Global AGEing and Adult Health (SAGE).SETTING: Household surveys in China, India, Russia, South Afric... | ['Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Cross-Sectional Studies', 'Disability Evaluation', 'Disabled Persons', 'Female', 'Global Health', 'Health Status', 'Humans', 'Male', 'Mobility Limitation', 'Population Surveillance', 'Risk Factors', 'Walking', 'World Health Organization'] | 24,438,515 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.400'], ['M01.150'], ['H02.403.371', 'N01.400.337'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Pharmacological implications of MMP-9 inhibition by ACE inhibitors. | Matrix metalloproteinase-9 (MMP-9) plays an important role in the onset and prognosis of myocardial infarction. Targets of angiotensin converting enzyme (ACE) inhibitors might include not only ACE but also MMP-9, and ACE seems to be closely associated with complications of hypertension such as cardiovascular remodeling... | ['Angiotensin-Converting Enzyme Inhibitors', 'Animals', 'Atherosclerosis', 'Catalytic Domain', 'Gene Expression Regulation', 'Humans', 'Matrix Metalloproteinase 9', 'Matrix Metalloproteinase Inhibitors', 'Myocardial Infarction', 'Peptidyl-Dipeptidase A'] | 19,355,890 | [['D27.505.519.389.745.085'], ['B01.050'], ['C14.907.137.126.307'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.480.205.360', 'D08.811.277.656.300.480.252.445', 'D08.811.277.656.300.480.525.700.350', 'D08.811.277.656.675... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term prognosis following zidovudine monotherapy in primary human immunodeficiency virus type 1 infection. | Eighty-five subjects with symptomatic primary (P) human immunodeficiency virus (HIV) type 1 infection were analyzed in a retrospective cohort study to investigate the long-term clinical benefit of antiretroviral treatment during PHIV infection. Zidovudine treatment was initiated (PHIV treatment group) in 21 persons a m... | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Anti-HIV Agents', 'Female', 'HIV Infections', 'HIV Long-Term Survivors', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Retrospective Studies', 'Reverse Transcriptase Inhibitors', 'Sexual Behavior', 'Zidovudine'] | 10,228,080 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['D27.505.954.122.388.077.088'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Elvitegravir/cobicistat/emtricitabine/tenofovir DF in HIV-infected patients with mild-to-moderate renal impairment. | In HIV-1-infected treatment-naive patients with mild-to-moderate renal impairment [creatinine clearance (CrCl): 50-89 mL/min], elvitegravir/cobicistat/emtricitabine/tenofovir DF (STB, n = 33) achieved high rates of virologic success (78.8%; 95% confidence interval: 61.1% to 91.0%) and was well tolerated through week 48... | ['Adenine', 'Adult', 'Anti-HIV Agents', 'Carbamates', 'Cobicistat', 'Cohort Studies', 'Deoxycytidine', 'Emtricitabine', 'Female', 'HIV Infections', 'Humans', 'Male', 'Middle Aged', 'Organophosphonates', 'Quinolones', 'Renal Insufficiency', 'Tenofovir', 'Thiazoles', 'Treatment Outcome'] | 25,469,527 | [['D03.633.100.759.138'], ['M01.060.116'], ['D27.505.954.122.388.077.088'], ['D02.241.081.251'], ['D02.241.081.251.203', 'D02.886.675.182', 'D03.383.129.708.189'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D03.383.742.680.245.500', 'D13.570.230.329', 'D13.570.685.245.500'], ['D03.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The outcome of patients with hypogammaglobulinemia in infancy and early childhood. | A 10-year prospective cohort study followed the evolution of antibodies in children less than 4 years of age with hypogammaglobulinemia. Three patterns were identified: in group 1, immunoglobulins and antibody production normalized;iin group 2, patients continued to have low IgG levels; and in group 3, IgG levels norma... | ['Agammaglobulinemia', 'Child, Preschool', 'Disease Progression', 'Female', 'Humans', 'IgG Deficiency', 'Immunoglobulin A', 'Immunoglobulin G', 'Immunoglobulin M', 'Infant', 'Male', 'Prospective Studies'] | 9,672,529 | [['C15.378.147.142', 'C15.604.515.032', 'C20.673.088'], ['M01.060.406.448'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.378.147.333.750', 'C20.673.430.750'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.790.651.114.619.026', 'D12.776.377.715.548.114.619.026'], ['D12.776.124.486.485.... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Four-way junction formation promoting ultrasensitive electrochemical detection of microRNA. | MicroRNAs (miRNAs) represent a class of biomarkers that are frequently deregulated in cancer cells and have shown a great promise for cancer classification and prognosis. Here, we endeavored to develop a DNA four-way junction based electrochemical sensor (4J-SENS) for ultrasensitive miRNA analysis. The developed sensor... | ['Base Sequence', 'Biosensing Techniques', 'DNA', 'Electrochemistry', 'Humans', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Limit of Detection', 'MicroRNAs', 'Nucleic Acid Hybridization'] | 24,047,131 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.601.043'], ['D13.444.308'], ['H01.181.529.307'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.428.080.125', 'C15.604.515.560.080.125', 'C20.683.515.528.080.125'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Cholesterol is increased in the exofacial leaflet of synaptic plasma membranes of human apolipoprotein E4 knock-in mice. | Inheritance of the apolipoprotein (apoE) epsilon4 allele is a risk factor for developing Alzheimer's disease (AD). The purpose of the present study was to determine effects of apoE-isoforms on the transbilayer distribution of cholesterol in synaptic plasma membranes (SPM) using mice expressing human apoE3 and apoE4. To... | ['Alzheimer Disease', 'Animals', 'Apolipoprotein E3', 'Apolipoprotein E4', 'Apolipoproteins E', 'Cell Membrane', 'Cholesterol', 'Humans', 'Lipid Bilayers', 'Male', 'Mice', 'Mice, Mutant Strains', 'Synaptic Membranes'] | 11,930,145 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['B01.050'], ['D10.532.091.500.500', 'D12.776.070.400.500.500', 'D12.776.521.120.500.500'], ['D10.532.091.500.750', 'D12.776.070.400.500.750', 'D12.776.521.120.500.750'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['A11.284.149'], [... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Tumour immunotherapy--leukocytes take up the fight. | The immune system can promote the elimination of tumours, but often immune responses are modulated or suppressed by the tumour microenvironment. In this joint Focus from Nature Reviews Cancer and Nature Reviews Immunology, leading researchers describe our current understanding of the complex interactions that occur bet... | ['Animals', 'Humans', 'Immunotherapy', 'Killer Cells, Natural', 'Leukocytes', 'Myeloid Cells', 'Neoplasms', 'T-Lymphocytes'] | 22,545,289 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['A11.627'], ['C04'], ['A11.118.637.555.567.569', 'A15.145.229.637.555.567.569', 'A15.382.490.555.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Considerations of pool size in the manufacture of plasma derivatives. | BACKGROUND: The pooling of human plasma from many donors for the purpose of manufacturing therapeutic proteins increases the risk of exposing recipients of these proteins to pathogens that may contaminate 1 or a few units included in the pool.STUDY DESIGN AND METHODS: This risk is estimated for a range of manufacturing... | ['Blood Proteins', 'Blood Transfusion', 'Communicable Disease Control', 'Humans', 'Plasma', 'Risk Factors'] | 8,823,448 | [['D12.776.124'], ['E02.095.135'], ['N06.850.780.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A12.207.152.693', 'A12.207.270.695', 'A15.145.693'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Diagnostic tests in the skin and serum of works sensitized to Bacillus subtilis enzymes. | Two allergen pools of commercial detergent enzymes were prepared as skin test reagents: (1) Carlsberg type, composed of three products containing subtilopeptidase A, and (2) BPN type, composed of two products containing subtilopeptidase B and alpha-amylase. In 100 non-exposed controls a reaction suggesting primary irri... | ['Bacillus subtilis', 'Detergents', 'Humans', 'Hypersensitivity', 'Immunity, Maternally-Acquired', 'Occupational Diseases', 'Occupations', 'Radioallergosorbent Test', 'Skin Tests'] | 406,100 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D27.720.877.265', 'J01.516.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543'], ['G12.450.570'], ['C24'], ['N01.824.547'], ['E01.370.225.812.735.830', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Effects of camelina meal supplementation on ruminal forage degradability, performance, and physiological responses of beef cattle. | Three experiments compared ruminal, physiological, and performance responses of beef steers consuming hay ad libitum and receiving grain-based supplements without (control) or with (CAM) the inclusion of camelina meal. In Exp. 1, 9 steers fitted with ruminal cannulas received CAM (2.04 kg of DM/d; n = 5) or control (2.... | ['Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Brassica', 'Cattle', 'Ceruloplasmin', 'Corticotropin-Releasing Hormone', 'Diet', 'Dietary Supplements', 'Fatty Acids, Unsaturated', 'Male', 'Thyrotropin-Releasing Hormone'] | 22,585,784 | [['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['B01.650.940.800.575.912.250.157.200'], ['B01.050.150.900.649.313.500.380.271'], ['D08.811.682.226', 'D12.776.124.050.130', 'D12.776.124.790.106.214', 'D12.776.157.160', 'D12.776.377.715.085.214', 'D12.776.556.151'], ['D06.472.699.327.740.1... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Kinetics of renin reaction in rat plasma (author's transl)]. | Important kinetic aspects of renin reaction were studied in order to evaluate the parameters that regulate the formation rate of angiotensin I. This rate decreased throughout the incubation period of normal rat plasma and it showed a linear increase when plasma was incubated with renin-substrate. When renin was added ... | ['Angiotensin II', 'Animals', 'Kinetics', 'Rats', 'Renin', 'Time Factors'] | 1,257,568 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649.313.992.635.505.700'], ['D08.811.277.656.074.500.780', 'D08.811.277.656.300.048.780', 'D08.811.277.656.837.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Heterologous induction of the retrotransposon Ty1: reverse transcriptase plays a key role in initiating the retrotransposition cycle]. | A new method was developed to study the mechanism of initiation of the retrotransposition cycle: retrotransposons of Drosophila melanogaster, gypsy, copia, and 17.6 were expressed in yeast under the control of potent yeast promoters. Expression of retrotransposons induced formation of viruslike particles (VLPs) associa... | ['Animals', 'Cloning, Molecular', 'Drosophila melanogaster', 'Genetic Vectors', 'HIV Reverse Transcriptase', 'HIV-1', 'RNA-Directed DNA Polymerase', 'Retroelements', 'Saccharomyces cerevisiae'] | 8,601,506 | [['B01.050'], ['E05.393.220'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G05.360.337'], ['D08.811.913.696.445.308.300.750.187', 'D12.776.964.775.375.545.875', 'D12.776.964.775.375.750.187', 'D12.776.964.775.562.764.875', 'D12.776.964.900.750.500.545.875', 'D12.776.964.900.750.500.750.187', 'D12.776.964.970... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Trigonal-bipyramidal geometry induced by an external water ligand in a sterically hindered iron salen complex, related to the active site of protocatechuate 3,4-dioxygenase. | A unique distorted trigonal-bipyramidal geometry observed for the non-heme iron center in protocatechuate 3,4-dioxygenase (3,4-PCD) was carefully examined utilizing a sterically hindered iron salen complex, which well reproduces the endogenous His2Tyr2 donor set with water as an external ligand. X-ray crystal structure... | ['Binding Sites', 'Catechols', 'Crystallography, X-Ray', 'Electrochemistry', 'Ethylenediamines', 'Ferric Compounds', 'Ligands', 'Models, Molecular', 'Nuclear Magnetic Resonance, Biomolecular', 'Protein Structure, Tertiary', 'Protocatechuate-3,4-Dioxygenase', 'Spectrum Analysis, Raman', 'Substrate Specificity', 'Water'] | 16,961,363 | [['G02.111.570.120'], ['D02.455.426.559.389.657.166'], ['E05.196.309.742.225'], ['H01.181.529.307'], ['D02.092.782.258.368'], ['D01.490.100'], ['D27.720.470.480'], ['E05.599.595'], ['E05.196.867.519.550'], ['G02.111.570.820.709.610'], ['D08.811.682.690.416.652'], ['E05.196.822.860', 'E05.196.867.890'], ['G02.111.835'],... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Liposome-based therapy of human ovarian cancer: parameters determining potency of negatively charged and antibody-targeted liposomes. | Liposomes containing cytotoxic agents may be highly efficacious for intracavitary therapy of malignancies such as ovarian carcinoma, which resides principally in the peritoneal cavity. We have examined in vitro the cytotoxicity of a variety of liposome-drug formulations against OVCAR-3, a human ovarian cancer cell line... | ['Antibodies, Monoclonal', 'Antineoplastic Agents', 'Cell Line', 'Endocytosis', 'Female', 'Humans', 'Immunization, Passive', 'Liposomes', 'Ovarian Neoplasms'] | 3,409,248 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D27.505.954.248'], ['A11.251.210'], ['G04.417'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400.330', 'E05.478.550.520'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.5... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
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