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Influence of food on frequency-dependent sexual activity of Drosophila melanogaster. | When two types of Drosophila are in competition, the frequency dependence of mating successes frequently is measured by direct observation of copulating pairs in "Elens-Wattiaux" observation chambers, the relative frequency of both types being varied. The present experiments, concerning white-ebony mutants in competiti... | ['Animals', 'Copulation', 'Drosophila melanogaster', 'Feeding Behavior', 'Female', 'Genotype', 'Male', 'Mutation', 'Phenotype'] | 2,508,615 | [['B01.050'], ['F01.145.113.252.748.200'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['G05.380'], ['G05.365.590'], ['G05.695']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The moderately halophilic bacterium Halomonas maura is a free-living diazotroph. | Halomonas maura is a moderately halophilic bacterium which lives in saline soils and synthesises an exopolysaccharide known as mauran. Strain S-31T grew in a nitrogen-free medium under an N2 atmosphere; the acetylene reduction assay proved positive under specific conditions. We identified the nifH gene in this strain b... | ['Base Sequence', 'DNA, Bacterial', 'Genes, Bacterial', 'Halomonas', 'Molecular Sequence Data', 'Nitrogen Fixation', 'Oxidoreductases', 'Phylogeny', 'Soil Microbiology'] | 15,727,823 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.212'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['B03.440.400.425.377.500', 'B03.660.250.350.500'], ['L01.453.245.667'], ['G02.111.071.630', 'G02.111.587.750', 'G02.607.560.750', 'G03.087.630', 'G06.6... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Leber's hereditary optic neuropathy differentially affects smaller axons in the optic nerve. | PURPOSE: Leber's hereditary optic neuropathy (LHON), though known to be due to 1 of 3 pathogenic mtDNA point mutations (nucleotide positions 11,778, 3460, and 14,484), usually manifests itself acutely in young adulthood with a stereotypical presentation of dyschromatopsia, loss of central vision, and loss of the papill... | ['Adult', 'Aged', 'Axons', 'Female', 'Humans', 'Microscopy, Electron', 'Nerve Fibers', 'Optic Atrophies, Hereditary', 'Optic Nerve', 'Retinal Ganglion Cells'] | 11,190,025 | [['M01.060.116'], ['M01.060.116.100'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402', 'E05.595.402'], ['A08.675.542', 'A11.671.501'], ['C10.292.700.225.500', 'C10.574.500.662', 'C11.270.564', 'C11.640.451.451', 'C16.320.... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Simultaneous determination of three Curcuminoids in Curcuma wenyujin Y.H.chen et C.Ling. by liquid chromatography-tandem mass spectrometry combined with pressurized liquid extraction. | A sensitive and efficient method based on pressurized liquid extraction (PLE) followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed for simultaneous identification and quantification of three Curcuminoids in Curcuma wenyujin Y.H.chen et C.Ling., a well known traditional Chinese medicinal h... | ['Chromatography, Liquid', 'Curcuma', 'Curcumin', 'Diarylheptanoids', 'Drugs, Chinese Herbal', 'Liquid-Liquid Extraction', 'Solvents', 'Tandem Mass Spectrometry', 'Time Factors'] | 23,648,558 | [['E05.196.181.400'], ['B01.650.940.800.575.912.250.618.937.900.166'], ['D02.455.326.146.485.222.222', 'D02.455.426.559.389.657.166.200', 'D02.455.426.559.694.222'], ['D02.455.326.146.485.222', 'D02.455.426.559.694'], ['D20.215.784.500.350', 'D26.335'], ['E05.196.155.650'], ['D27.720.844'], ['E05.196.566.880'], ['G01.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Monosynaptic striatal inputs to the nigrotegmental neurons: an electron microscopic study in the cat. | The cat substantia nigra (SN) pars reticulata (SNR) has been observed electron microscopically after ibotenic acid injections into the caudate nucleus (Cd) and horseradish peroxidase injections into the nucleus tegmenti pedunculopontinus pars compacta (TPC). As a result, degenerating striatal terminals were found to ma... | ['Animals', 'Cats', 'Corpus Striatum', 'Horseradish Peroxidase', 'Microscopy, Electron', 'Substantia Nigra', 'Synapses', 'Tegmentum Mesencephali'] | 2,720,400 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A08.186.211.200.885.287.249.487'], ['D08.811.682.732.512'], ['E01.370.350.515.402', 'E05.595.402'], ['A08.186.211.132.659.413.656'], ['A08.850', 'A11.284.149.165.420.780'], ['A08.186.211.132.659.413.875']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of protein microarrays to define the humoral immune response in leprosy patients and identification of disease-state-specific antigenic profiles. | Although the global prevalence of leprosy has decreased over the last few decades due to an effective multidrug regimen, large numbers of new cases are still being reported, raising questions as to the ability to identify patients likely to spread disease and the effects of chemotherapy on the overall incidence of lepr... | ['Antibodies, Bacterial', 'Antigens, Bacterial', 'Glycolipids', 'Humans', 'Leprosy', 'Leprosy, Lepromatous', 'Leprosy, Tuberculoid', 'Protein Array Analysis', 'Serologic Tests'] | 16,966,411 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D23.050.161'], ['D09.400.410', 'D10.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.410.040.552.475.371'], ['C01.150.252.410.040.552.475.371.775.500'], ['C01.150.252.410.040.552.475.371.850.500'], ['E... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessment and correlates of self-esteem following stroke using a pictorial measure. | OBJECTIVE: To describe the characteristics of a non-verbal measure of self-esteem in a sample of individuals in the acute phase following stroke.DESIGN: Acute-phase stroke survivors (n=156) were administered measures of self-esteem, depression, anxiety, general emotional distress and cognitive functioning during admiss... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Male', 'Middle Aged', 'Psychological Tests', 'Self Concept', 'Stroke'] | 17,148,519 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.711'], ['F01.752.747.792'], ['C10.228.140.300.775', 'C14.907.253.855']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Proton pump inhibitor therapy use does not predispose to small intestinal bacterial overgrowth. | OBJECTIVES: Small intestinal bacterial overgrowth (SIBO) occurs due to alteration of the microbiota within the upper gastrointestinal tract. Proton pump inhibitor (PPI) therapy has been suggested as a risk factor for SIBO; however, the published reports have yielded conflicting results on the association between PPI th... | ['Blind Loop Syndrome', 'Breath Tests', 'Female', 'Glucose', 'Humans', 'Hydrogen', 'Intestine, Small', 'Male', 'Methane', 'Middle Aged', 'Proton Pump Inhibitors'] | 22,334,250 | [['C06.405.469.637.145', 'C18.452.603.145'], ['E01.370.100'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.406', 'D01.362.340'], ['A03.556.124.684'], ['D02.455.326.146.571'], ['M01.060.116.630'], ['D27.505.519.389.848']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Duration of enhancement and scan timing in three-dimensional contrast-enhanced MR angiography using the elliptical centric phase-encoding technique]. | In the present study, we quantitatively investigated the relationship between the signal intensity in a vessel and the duration of contrast enhancement as well as scan timing in 3D contrast-enhanced MR angiography using an elliptical centric phase-encoding technique. A tube phantom filled with Gd-DTPA, acting as a vess... | ['Contrast Media', 'Image Enhancement', 'Imaging, Three-Dimensional', 'Magnetic Resonance Angiography', 'Phantoms, Imaging', 'Time Factors'] | 15,001,871 | [['D27.505.259.500', 'D27.720.259'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.825.500.500', 'E01.370.370.050.500'], ['E07.671'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Distribution and latency of muscle responses to transcranial magnetic stimulation of motor cortex after spinal cord injury in humans. | Noninvasive transcranial magnetic stimulation (TMS) of the motor cortex was used to evoke electromyographic (EMG) responses in persons with spinal cord injury (n = 97) and able-bodied subjects (n = 20, for comparative data). Our goal was to evaluate, for different levels and severity of spinal cord injury, potential di... | ['Adolescent', 'Adult', 'Aged', 'Electric Stimulation', 'Electromyography', 'Evoked Potentials, Motor', 'Female', 'Humans', 'Male', 'Middle Aged', 'Motor Cortex', 'Motor Neurons', 'Muscle Contraction', 'Muscle, Skeletal', 'Neural Conduction', 'Reaction Time', 'Sensory Thresholds', 'Spinal Cord Injuries', 'Transcranial ... | 9,989,466 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.723.402'], ['E01.370.405.255', 'E01.370.530.255'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['A08.675... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
8-Alkylamino-substituted analogs of N6-cyclopentyladenosine are partial agonists for the cardiovascular adenosine A1 receptors in vivo. | Partial adenosine A1 receptor agonists with reduced intrinsic activity at the cardiovascular system would be promising for therapeutic application (e.g., as antilipolytic agents). In the present study a series of 8-alkylamino [methyl (M)-, ethyl (E)-, propyl (P)-, butyl (B)- and cyclopentyl (CP)-] derivatives of N6-cyc... | ['Adenosine', 'Animals', 'Blood Pressure', 'Guanosine Triphosphate', 'Heart Rate', 'Male', 'Purinergic P1 Receptor Agonists', 'Rats', 'Rats, Wistar', 'Structure-Activity Relationship'] | 9,353,401 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D03.633.100.759.646.454.504', 'D13.695.667.454.504', 'D13.695.827.426.504'], ['E01.370.600.875.500', 'G09.330.380.500'], ['D27.505.519.625.725.200.100', 'D27.505.696.577.725.200.100'], ['B01.05... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
MR elastography of the breast:preliminary clinical results. | PURPOSE: Imaging of breast tumors and various breast tissues using magnetic resonance (MR) elastography (MRE) to explore the potential of elasticity as a new parameter for the diagnosis of breast lesions.METHODS: Low-frequency mechanical waves are transmitted into breast tissue by means of an oscillator. The local char... | ['Adult', 'Aged', 'Breast', 'Breast Diseases', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Carcinoma, Lobular', 'Diagnosis, Differential', 'Elasticity', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Middle Aged', 'Reference Values', 'Sensitivity and Specificity'] | 12,101,471 | [['M01.060.116'], ['M01.060.116.100'], ['A01.236'], ['C17.800.090'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['C04.557.470.200.025.305', 'C04.557.470.615.305', 'C04.588.180.437', 'C17.800.090.500.437'], ['E01.171'], ['G01.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Optical coherence tomography and focal macular electroretinogram in eyes with epiretinal membrane and macular pseudohole. | PURPOSE: To determine the morphology of macular pseudoholes (MPHs) and the relationship of morphology to macular function.DESIGN: Observational case series.METHODS: Optical coherence tomography (OCT) was performed on 42 eyes of 42 consecutive patients with an epiretinal membrane (ERM) and an MPH. The diameters of the M... | ['Adult', 'Aged', 'Aged, 80 and over', 'Electroretinography', 'Epiretinal Membrane', 'Female', 'Fovea Centralis', 'Humans', 'Interferometry', 'Macula Lutea', 'Male', 'Middle Aged', 'Retinal Perforations', 'Tomography', 'Visual Acuity'] | 12,834,671 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.380.225', 'E01.370.405.270'], ['C11.768.328'], ['A09.371.729.522.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.490'], ['A09.371.729.522'], ['M01.060.116.630'], ['C11.768.740'], ['E01.370.350.825'], ['E01.370.380.850.950', 'F02.463... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Isolation of the mouse mammary tumor virus sequences not transmitted as germinal provirus in the C3H and RIII mouse strains. | Radioactive 60-70S RNA from the mouse mammary tumor virus (MMTV) produced by the C3H mouse mammary tumor cell line (Mm5mt) hybridized to a greater extent, and at a lower Cot1/2 value, to the DNA of C3H mammary tumor cells than to the DNA of C3H liver cells. The 125I-labeled MMTV (C3H) 60-40S RNA was annealed to a vast ... | ['Animals', 'Base Sequence', 'Cell Line', 'DNA', 'DNA, Neoplasm', 'Liver', 'Mammary Neoplasms, Experimental', 'Mammary Tumor Virus, Mouse', 'Mice', 'Mice, Inbred C3H', 'Mice, Inbred Strains', 'Nucleic Acid Hybridization'] | 191,657 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['D13.444.308'], ['D13.444.308.425'], ['A03.620'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.496.843'], ['B04.613.807.124.500', 'B04.820.650.124.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.3... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Gunshot Injuries to the Extremity: Is Immediate General Surgery Presence Needed? | Gunshot wounds (GSW) are becoming increasingly prevalent in urban settings. GSW to the trunk mandate full trauma activation and immediate surgeon response because of the high likelihood of operative intervention. Extremity GSW proximal to the knee/elbow also require full trauma activation based on American College of S... | ['Adolescent', 'Adult', 'Arm Injuries', 'Female', 'Health Services Needs and Demand', 'Humans', 'Hypotension', 'Injury Severity Score', 'Leg Injuries', 'Male', 'Middle Aged', 'Multiple Trauma', 'Patient Selection', 'Retrospective Studies', 'Trauma Centers', 'Wounds, Gunshot', 'Young Adult'] | 30,268,174 | [['M01.060.057'], ['M01.060.116'], ['C26.088'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.514'], ['E05.318.308.940.968.875.500', 'E05.944.600', 'N04.452.859.564.800.500', 'N05.715.360.300.715.500.800.400'], ['C26.558'], ['M01.060.116.630'], ['C26.640'], ['E05.581.500... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In silico identification of small molecules as novel LXR agonists for the treatment of cardiovascular disease and cancer. | Liver X receptor (LXR), a member of the nuclear receptor superfamily, mainly serves as a reverse cholesterol transporter in lipid metabolism. It has been demonstrated that LXR is a promising target for the treatment of cardiovascular diseases. LXR is also involved in cancer metabolism, glucose homeostasis, immunity, an... | ['Antineoplastic Agents', 'Cardiovascular Agents', 'Cardiovascular Diseases', 'Computer Simulation', 'Humans', 'Ligands', 'Liver X Receptors', 'Molecular Docking Simulation', 'Neoplasms', 'Protein Binding'] | 29,450,657 | [['D27.505.954.248'], ['D27.505.954.411'], ['C14'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.480'], ['D12.776.260.531', 'D12.776.826.194'], ['E05.599.595.249', 'L01.224.160.249'], ['C04'], ['G02.111.679', 'G03.808']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
In vivo metabolism of 3H-testosterone in adult male rats: effects of estrogen administration. | The metabolism of testosterone (T) was studied in normal adult male rats using a constant infusion of trace amounts of the 3H-steroid into a tail vein for 3 h in order to attain a state of equilibrium. Samples of plasma, liver, kidney, prostate, seminal vesicles and muscle were analysed for 3H-testosterone, 3H-5alpha-d... | ['Androstane-3,17-diol', 'Animals', 'Dihydrotestosterone', 'Estradiol', 'Kidney', 'Liver', 'Male', 'Metabolic Clearance Rate', 'Muscles', 'Prostate', 'Rats', 'Seminal Vesicles', 'Testosterone'] | 1,166,480 | [['D04.210.500.054.040.080', 'D06.472.334.851.968.500'], ['B01.050'], ['D04.210.500.054.040.248', 'D06.472.334.851.968.964'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['A05.810.453'], ['A03.620'], ['E01.370.225.843', 'E05.200.843', 'G03.490', 'G07.690.595', 'G07.690.725.513'], ['A02.633', 'A10.690'], ['A... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analyzing bivariate repeated measures for discrete and continuous outcome variables. | A considerable body of literature has arisen over the past 15 years for analyzing univariate repeated measures data. However, it is rare in applied biomedical research for interest to be restricted to a single outcome measure. In this paper, we consider the case of bivariate repeated measures. We apply a generalized es... | ['Analysis of Variance', 'Anti-Inflammatory Agents, Non-Steroidal', 'Biometry', 'Crohn Disease', 'Data Interpretation, Statistical', 'Humans', 'Linear Models', 'Methotrexate', 'Models, Statistical', 'Multicenter Studies as Topic', 'Randomized Controlled Trials as Topic', 'Regression Analysis'] | 8,672,710 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['E05.318.740.225', 'N06.850.505.200'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.30... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Electronmicroscopic histochemical investigation of the surface of the cell membrane of the renal tubules with the use of ruthenium red and lantanum nitrate. | The renal tubules were investigated with the use of ruthenium red and lanthanum nitrate to titrate the carbohydrate groups which are localized on the differentiated surface of the cell membranes and intercellular spaces. Ruthenium red visualized the surface coat which is tightly bound to the outer lamellae of the cell ... | ['Animals', 'Carbohydrates', 'Cell Membrane', 'Formaldehyde', 'Glutaral', 'Kidney Tubules', 'Lanthanum', 'Rats', 'Ruthenium Red'] | 416,997 | [['B01.050'], ['D09'], ['A11.284.149'], ['D02.047.407'], ['D02.047.532'], ['A05.810.453.736.560'], ['D01.268.558.362.500', 'D01.552.550.399.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['D01.210.837', 'D01.625.800', 'D01.765.765']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Crystal structures of the pyrazinamide-p-aminobenzoic acid (1/1) cocrystal and the transamidation reaction product 4-(pyrazine-2-carboxamido)benzoic acid in the molten state. | The synthesis of pharmaceutical cocrystals is a strategy to enhance the performance of active pharmaceutical ingredients (APIs) without affecting their therapeutic efficiency. The 1:1 pharmaceutical cocrystal of the antituberculosis drug pyrazinamide (PZA) and the cocrystal former p-aminobenzoic acid (p-ABA), C7H7NO2·C... | ['Aminobenzoates', 'Antitubercular Agents', 'Benzoates', 'Benzoic Acid', 'Crystallography, X-Ray', 'Hydrogen Bonding', 'Models, Molecular', 'Pyrazinamide', 'Pyrazines'] | 26,524,176 | [['D02.241.223.100.050', 'D02.455.426.559.389.127.020'], ['D27.505.954.122.085.255'], ['D02.241.223.100', 'D02.455.426.559.389.127'], ['D02.241.223.100.120', 'D02.455.426.559.389.127.117'], ['E05.196.309.742.225'], ['G02.282'], ['E05.599.595'], ['D03.383.679.750'], ['D03.383.679']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Patient safety incidents are common in primary care: A national prospective active incident reporting survey. | BACKGROUND: The study objectives were to describe the incidence and the nature of patient safety incidents (PSIs) in primary care general practice settings, and to explore the association between these incidents and practice or organizational characteristics.METHODS: GPs, randomly selected from a national influenza sur... | ['Female', 'France', 'Humans', 'Incidence', 'Male', 'Patient Safety', 'Primary Health Care', 'Prospective Studies', 'Risk Management'] | 28,196,076 | [['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['N06.850.135.060.075.399'], ['N04.590.233.727'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650']... | ['Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Reconstruction and analysis of the pupil dilation signal: Application to a psychophysiological affective protocol. | Pupil dilation (PD) dynamics reflect the interactions of sympathetic and parasympathetic innervations in the iris muscle. Different pupillary responses have been observed with respect to emotionally characterized stimuli. Evidences of the correlation between PD and respiration, heart rate variability (HRV) and blood pr... | ['Affect', 'Algorithms', 'Emotions', 'Humans', 'Psychophysiology', 'Pupil', 'Signal Processing, Computer-Assisted'] | 24,109,610 | [['F01.470.047'], ['G17.035', 'L01.224.050'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.525.812', 'F02.830', 'F04.096.795', 'H01.158.782.795'], ['A09.371.060.450.780', 'A09.371.894.513.780'], ['L01.224.800']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Conditional reverse tet-transactivator mouse strains for the efficient induction of TRE-regulated transgenes in mice. | Tetracycline or doxycycline (dox)-regulated control of genetic elements allows inducible, reversible and tissue specific regulation of gene expression in mice. This approach provides a means to investigate protein function in specific cell lineages and at defined periods of development and disease. Efficient and stable... | ['Animals', 'Gene Expression Regulation', 'Mice', 'Mice, Transgenic', 'Models, Genetic', 'Repressor Proteins', 'Response Elements', 'Transgenes'] | 24,743,474 | [['B01.050'], ['G05.308'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['E05.599.395.397'], ['D12.776.260.703', 'D12.776.930.780'], ['G02.111.570.080.689.330.700', 'G02.111.570.080.689.675.700', 'G05.360.080.689.330.700', 'G05.360.080.689.675.700'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Magnetic resonance imaging in the management of diabetic foot infection. | A prospective study was carried out of 22 patients admitted with 25 diabetic foot infections. All had cellulitis, 12 had discharging ulcers and eight had digital gangrene. In one case magnetic resonance imaging (MRI) was unhelpful owing to patient movement. Thirteen scans suggested deep-seated infection, including absc... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cellulitis', 'Diabetic Foot', 'Female', 'Humans', 'Infections', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Prospective Studies', 'Sensitivity and Specificity'] | 8,689,178 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.800.130', 'C01.830.200', 'C17.300.185', 'C23.550.470.756.200'], ['C14.907.320.191', 'C17.800.893.592.450.200', 'C19.246.099.500.191', 'C19.246.099.937.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01'], ['E01.370.350.825.500'], ['M01.060... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evidence for pH-dependent multiple conformers in iron(II) heme-human serum albumin: spectroscopic and kinetic investigation of carbon monoxide binding. | Human serum albumin (HSA), the most prominent protein in plasma, is best known for its exceptional ligand binding capacity. HSA participates in heme scavenging by binding the macrocycle at fatty acid site 1. In turn, heme endows HSA with globin-like reactivity and spectroscopic properties. A detailed pH-dependent kinet... | ['Binding Sites', 'Carbon Monoxide', 'Ferrous Compounds', 'Heme', 'Humans', 'Hydrogen-Ion Concentration', 'Kinetics', 'Models, Molecular', 'Serum Albumin', 'Spectrum Analysis, Raman'] | 21,894,504 | [['G02.111.570.120'], ['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['D01.490.200'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['E05.599.595'], [... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of centerin: a novel human germinal center B cell-restricted serpin. | For naive B cells to mature in response to antigen triggering and become either plasma cells or memory B cells, a complex array of events takes place within germinal centers (GC) of secondary lymphoid organs. With the long-term objective of defining and characterizing molecules that control the generation of GC, we hav... | ['Alternative Splicing', 'Amino Acid Sequence', 'B-Lymphocytes', 'CD40 Ligand', 'Chromosomes, Human, Pair 14', 'Cloning, Molecular', 'Enzyme Induction', 'Gene Expression Profiling', 'Germinal Center', 'HL-60 Cells', 'Humans', 'Molecular Sequence Data', 'Neoplasm Proteins', 'RNA, Antisense', 'RNA, Messenger', 'RNA, Neop... | 11,069,088 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D12.644.276.374.750.124', 'D12.776.395.550.185', 'D12.776.467.374.750.124', 'D12.776.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Improve scheduling of fistula patients to slash unnecessary costs, improve care for ESRD. | When you're dealing with a high-cost illness like ESRD, finding an easy source of six figure savings while enhancing access and quality is a significant accomplishment. But that's exactly what one hospital has done, using a simple strategy that virtually every organization with ESRD patients can adopt. | ['Appointments and Schedules', 'Cost Savings', 'Humans', 'Kidney Failure, Chronic', 'Quality Assurance, Health Care', 'Surgery Department, Hospital', 'Vascular Fistula', 'Virginia'] | 11,066,293 | [['N04.452.095'], ['N03.219.151.160.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['N04.761.700', 'N05.700'], ['N02.278.216.500.968.750', 'N04.452.442.452.422.750'], ['C14.240.850.984', 'C14.907.933', 'C23.300.575.950'], ['Z01.107.567.875.075.837', '... | ['Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Significance of epidermal growth factor receptor in advanced ovarian cancer. | PURPOSE: The purpose of this study was to investigate the significance of epidermal growth factor receptor (EGF-R) expression in a group of advanced ovarian carcinomas.PATIENTS AND METHODS: The study was conducted on 72 previously untreated patients with International Federation of Gynecology and Obstetrics (FIGO) stag... | ['Analysis of Variance', 'ErbB Receptors', 'Female', 'Humans', 'Iodine Radioisotopes', 'Life Tables', 'Middle Aged', 'Ovarian Neoplasms', 'Prognosis', 'Prospective Studies', 'Regression Analysis', 'Risk Factors'] | 1,548,517 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['E05.318.308.985.475', 'E05.318.740.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sensory impairments and their associations with functional disability in a sample of the oldest-old. | PURPOSE: Research focusing on the consequences of sensory impairments for the everyday competence of the oldest-old is emerging. The two main goals of this study were to document the prevalence of self-reported vision, hearing, and dual sensory impairment and to explore associations of these impairments with functional... | ['Activities of Daily Living', 'Aged, 80 and over', 'Cross-Sectional Studies', 'Disability Evaluation', 'Female', 'Hearing Disorders', 'Humans', 'Male', 'New York City', 'Prevalence', 'Quality of Life', 'Regression Analysis', 'Self Report', 'Vision Disorders'] | 24,682,668 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.400'], ['C09.218.458', 'C10.597.751.418', 'C23.888.592.763.393'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.87... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
DABCO-bis(sulfur dioxide), DABSO, as a convenient source of sulfur dioxide for organic synthesis: utility in sulfonamide and sulfamide preparation. | The charge-transfer complex generated from the combination of DABCO and sulfur dioxide, DABSO, is a bench-stable colorless solid suitable for use in organic synthesis as a replacement for gaseous sulfur dioxide. The complex can be combined with Grignard reagents to form sulfinates, which can then be converted in situ t... | ['Crystallography, X-Ray', 'Models, Molecular', 'Molecular Structure', 'Piperazines', 'Stereoisomerism', 'Sulfonamides', 'Sulfur Dioxide'] | 21,866,926 | [['E05.196.309.742.225'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['D03.383.606'], ['G02.607.445.682'], ['D02.065.884', 'D02.886.590.700'], ['D01.362.810', 'D01.650.550.850.925', 'D01.875.825.925']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The molecular basis of granuloma formation in schistosomiasis. III. In vivo effects of a T cell-derived suppressor effector factor and IL-2 on granuloma formation. | Granuloma formation in schistosomiasis is characterized by the formation of a large lesion in acutely infected animals which subsequently decreases in size as disease progresses into the chronic phase. These in vivo studies confirm and extend previous in vitro observations on the regulation of granulomatous hypersensit... | ['Adjuvants, Immunologic', 'Animals', 'Antigens, Helminth', 'Cells, Cultured', 'Granuloma', 'H-2 Antigens', 'Interleukin-2', 'Lymphocyte Activation', 'Mice', 'Mice, Inbred C57BL', 'Schistosomiasis mansoni', 'Suppressor Factors, Immunologic', 'T-Lymphocytes'] | 2,500,484 | [['D27.505.696.477.067'], ['B01.050'], ['D23.050.223'], ['A11.251'], ['C15.604.515.292', 'C23.550.382'], ['D23.050.301.500.100.350', 'D23.050.301.500.400.199', 'D23.050.705.552.100.350', 'D23.050.705.552.410.199'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.776.467.374.480.37... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of age and physical health on processing speed in HIV. | The impact of age and physical health on processing speed was investigated in 42 non-demented HIV+ individuals ranging in age from 30 to 75. We used the Medical Outcomes Study-HIV Healthy Survey (MOS-HIV) to measure self-reported physical health, neuropsychological tests to measure psychomotor and cognitive processing ... | ['Adult', 'Aged', 'Aging', 'Executive Function', 'Female', 'HIV Infections', 'Health Status', 'Humans', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Surveys and Questionnaires', 'Task Performance and Analysis'] | 26,468,908 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['F02.463.217'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Early eyelid rehabilitation in facial nerve paralysis. | Upper-lid gold-weight insertions and lower-lid-shortening procedures are standard surgical techniques used to restore eyelid function and protect the cornea in patients with facial nerve paralysis. Different opinions exist in the literature regarding the correct timing and the morbidity of these interventions. The retr... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Eyelid Diseases', 'Eyelids', 'Facial Paralysis', 'Female', 'Gold', 'Humans', 'Male', 'Middle Aged', 'Prostheses and Implants', 'Retrospective Studies', 'Surgery, Plastic', 'Time Factors'] | 8,822,716 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['C11.338'], ['A01.456.505.420.504', 'A09.371.337'], ['C07.465.327', 'C10.597.622.214', 'C23.888.592.636.214'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E07.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Production of Agaricus bisporus on substrates pre-colonized by Scytalidium thermophilum and supplemented at casing with protein-rich supplements. | The objective of this study was to evaluate performance of Agaricus bisporus (Ab) on substrates pre-colonized by Scytalidiumthermophilum (St), a thermophilic fungus known to enhance yields of Ab and increase selectivity of the substrate. The radial extension rate (RER) of the mycelium of three strains of St and their i... | ['Agaricus', 'Ascomycota', 'Colony Count, Microbial', 'Mycelium', 'Plant Proteins', 'Poaceae', 'Soil', 'Substrate Specificity'] | 19,457,658 | [['B01.300.179.100.105'], ['B01.300.107'], ['E01.370.225.875.220', 'E05.200.875.220'], ['A19.687'], ['D12.776.765'], ['B01.650.940.800.575.912.250.822'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['G02.111.835']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Ultrasensitive assay for measuring the intact (1-39) ACTH molecule: an asset in depression research. | This study investigates the utility for depression research of an assay for intact (1-39) adrenocorticotropic hormone (ACTH) versus that of a previously employed (i.e., 1-17, 1-24 sequences) ACTH assay. ACTH plasma levels were measured using two different ACTH assays (labeled as intact versus nonintact) in 10 minor and... | ['Adrenocorticotropic Hormone', 'Adult', 'Corticotropin-Releasing Hormone', 'Depressive Disorder', 'Dexamethasone', 'Female', 'Humans', 'Hydrocortisone', 'Male', 'Middle Aged', 'Patient Admission', 'Radioimmunoassay', 'Reference Values'] | 8,047,242 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['M01.060.116'], ['D06.472.699.327.740.140', 'D12.644.400.400.740.140', 'D12.644.548.365.740.140', 'D12.776.631.650.405... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The posterior radial epiphysis free flap: a new donor site. | The authors present the anatomy and clinical applications of a new donor site for free or pedicled transfers. It is localised on the posterior aspect of the forearm, over the distal radius, and based on a posterior branch of the anterior interosseous artery. It can be used as a free skin flap, osteoperiosteal or osteoc... | ['Adult', 'Female', 'Finger Injuries', 'Fingers', 'Forearm', 'Humans', 'Male', 'Middle Aged', 'Radius', 'Skin Transplantation', 'Surgical Flaps'] | 2,804,511 | [['M01.060.116'], ['C26.448.429'], ['A01.378.800.667.430'], ['A01.378.800.585'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.835.232.087.090.700'], ['E02.095.147.725.700', 'E04.680.275.850', 'E04.936.580.700'], ['A10.850.710', 'E07.862.710']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Anteromedial Meniscofemoral Ligament of the Anterior Horn of the Medial Meniscus: Clinical, Magnetic Resonance Imaging, and Arthroscopic Features. | PURPOSE: To describe the clinical, arthroscopic, and magnetic resonance imaging (MRI) findings of knees with anomalous insertion of the anterior horn of the medial meniscus (AHMM) into the intercondylar notch via an anteromedial meniscofemoral ligament (AMMFL).METHODS: A total of 2,503 arthroscopic knee surgeries perfo... | ['Adolescent', 'Adult', 'Anterior Cruciate Ligament', 'Arthroscopy', 'Female', 'Humans', 'Knee Injuries', 'Knee Joint', 'Magnetic Resonance Imaging', 'Male', 'Menisci, Tibial', 'Middle Aged', 'Retrospective Studies', 'Young Adult'] | 29,402,584 | [['M01.060.057'], ['M01.060.116'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558.554'], ['A02.835.583.475'], ['E01.370.350.825.500'], ['A02.165.308.538.500', 'A02.835.583.475.590', ... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fibrinogen: evolution of the structure-function concept. Keynote address at fibrinogen 2000 congress. | Coagulation of blood is such an evident phenomenon that its observation can be traced back to earliest historical times. The great philosophers and physicians of antiquity discussed and provided interesting explanations. However, it was not until the end of the seventeenth century that the structural component of the b... | ['Fibrinogen', 'Humans', 'Structure-Activity Relationship'] | 11,460,464 | [['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.830', 'G07.690.773.997']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Diabetic retinopathy: twelve-year incidence and progression]. | INTRODUCTION: Diabetic retinopathy (DR) it is the main cause of preventable blindness in productive-age adults. The rate of progression to blindness from DR differs among countries and populations.MATERIAL AND METHODS: In order to report the incidence and progression of DR after 12 years of follow-up in a cohort (n = 1... | ['Adult', 'Aged', 'Blood Glucose', 'Cohort Studies', 'Data Interpretation, Statistical', 'Diabetes Mellitus, Type 2', 'Diabetic Retinopathy', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Glycated Hemoglobin A', 'Humans', 'Longitudinal Studies', 'Male', 'Mexico', 'Middle Aged', 'Myocardial Infarction', 'Time F... | 15,910,698 | [['M01.060.116'], ['M01.060.116.100'], ['D09.947.875.359.448.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['C18.452.394.750.149', 'C19.246.300'], ['C11.768.257', 'C14.907... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Paranoid schizophrenia: non-specificity of neuropsychological vulnerability markers. | During stages of remission, patients with paranoid schizophrenia seldom show severe attentional or information-processing dysfunctions, except in cases of long-term chronicity. The diagnostic specificity of four putative psychological vulnerability indicators of schizophrenia - the Span of Apprehension, the degraded st... | ['Adult', 'Antipsychotic Agents', 'Attention', 'Depressive Disorder', 'Diagnosis, Differential', 'Discrimination Learning', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Perceptual Masking', 'Psychomotor Performance', 'Reference Values', 'Schizophrenia, Paranoid'] | 9,335,201 | [['M01.060.116'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F02.830.104.214'], ['F03.600.300'], ['E01.171'], ['F02.463.425.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.711.513'], ['F02.463.593.071.594', 'F02.463.593.932.733', 'G07.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Possible link between Hg and Cd accumulation in the brain of long-finned pilot whales (Globicephala melas). | The bioaccumulation of metals was investigated by analysis of liver, kidney, muscle and brain tissue of a pod of 21 long-finned pilot whales (Globicephala melas) of all ages stranded in Scotland, UK. The results are the first to report cadmium (Cd) passage through the blood-brain barrier of pilot whales and provide a c... | ['Animals', 'Brain', 'Cadmium', 'Environmental Monitoring', 'Mercury', 'Scotland', 'Water Pollutants, Chemical', 'Whales, Pilot'] | 26,748,005 | [['B01.050'], ['A08.186.211'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['Z01.542.363.766'], ['D27.888.284.903.655'], ['B01.050.150.900.649.313.875.267.920']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Targeting chronic lymphocytic leukemia using CIGB-300, a clinical-stage CK2-specific cell-permeable peptide inhibitor. | Chronic lymphocytic leukemia (CLL) remains an incurable malignancy, urging for the identification of new molecular targets for therapeutic intervention. CLL cells rely on overexpression and hyperactivation of the ubiquitous serine/threonine protein kinase CK2 for their viability in vitro. CIGB-300 is a cell-permeable s... | ['Aged', 'Aged, 80 and over', 'Animals', 'Apoptosis', 'Casein Kinase II', 'Cell Growth Processes', 'Cell Line, Tumor', 'Cell Survival', 'Humans', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Male', 'Mice', 'Mice, Nude', 'Middle Aged', 'PTEN Phosphohydrolase', 'Peptides, Cyclic', 'Phosphatidylinositol 3-Kinases', 'Protein... | 24,473,900 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050'], ['G04.146.954.035'], ['D08.811.913.696.620.682.700.140.600', 'D12.776.476.150.600'], ['G04.161', 'G07.345.249.410'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.428.080.125', 'C15.604.515.... | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
PDE10A and ADCY5 mutations linked to molecular and microstructural basal ganglia pathology. | BACKGROUND: Striatal cyclic adenosine monophosphate activity modulates movement and is determined from the balance between its synthesis by adenylate cyclase 5 (ADCY5) and its degradation by phosphodiesterase 10A (PDE10A).OBJECTIVE: We assessed the integrity of striatocortical pathways, in vivo, in 2 genetic hyperkinet... | ['Adenylyl Cyclases', 'Basal Ganglia', 'Corpus Striatum', 'Dopamine Plasma Membrane Transport Proteins', 'Globus Pallidus', 'Humans', 'Mutation', 'Neostriatum', 'Neurons', 'Parkinsonian Disorders', 'Phosphoric Diester Hydrolases', 'Substantia Nigra'] | 30,345,538 | [['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['A08.186.211.200.885.287.249'], ['A08.186.211.200.885.287.249.487'], ['D12.776.157.530.450.625.124', 'D12.776.157.530.562.374.500.500', 'D12.776.157.530.937.500', 'D12.776.543.585.450.625.124', 'D12.776.543.585.562.374.500.500', 'D12.776.543.585.937.500']... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Detection of Anaplastic Lymphoma Kinase-Rearranged Mesothelioma Cells in Ascites by Companion Diagnostics. | BACKGROUND: A case of peritoneal mesothelioma with an anaplastic lymphoma kinase (ALK) translocation was identified, and we conducted further studies to obtain diagnostic and therapeutic insights. We believe that this is the first report describing the cytology of this new tumor type.CASE: A teenage woman was referred ... | ['Adenocarcinoma', 'Adolescent', 'Anaplastic Lymphoma Kinase', 'Ascites', 'Cytodiagnosis', 'Female', 'Gene Rearrangement', 'Humans', 'Mesothelioma', 'Retrospective Studies'] | 31,661,685 | [['C04.557.470.200.025'], ['M01.060.057'], ['D08.811.913.696.620.682.725.400.002', 'D12.776.543.750.630.002'], ['C23.550.081'], ['E01.370.225.500.384', 'E05.200.500.384', 'E05.242.384'], ['G05.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.470.035.510', 'C04.557.470.660.510'], ['E05.318.372.500.500.5... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pittsburgh Regional Healthcare Initiative: a systems approach for achieving perfect patient care. | The Pittsburgh Regional Healthcare Initiative (PRHI) is an innovative model for health system change based on regionwide shared learning. By linking patient outcomes data with processes of care and sharing that information widely, PRHI supports measurable improvements in regionwide clinical practice and patient safety.... | ['Humans', 'Information Dissemination', 'Interinstitutional Relations', 'Leadership', 'Learning', 'Models, Organizational', 'Organizational Case Studies', 'Organizational Innovation', 'Outcome and Process Assessment, Health Care', 'Pennsylvania', 'Regional Medical Programs', 'Safety Management', 'Staff Development', 'T... | 14,515,891 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.143.443'], ['N04.452.822.400'], ['F01.752.609'], ['F02.463.425', 'F02.784.629.529'], ['E05.599.670', 'N04.452.534'], ['N03.349.380.710', 'N05.715.360.455'], ['N04.452.610'], ['N04.761.559', 'N05.715.360.575'], ['Z01.107.567.875.075.550', 'Z01.107.567.875.350.550',... | ['Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Texture based classification of the severity of mitral regurgitation. | Clinically, the severity of valvular regurgitation is assessed by manual tracing of the regurgitant jet in the respective chambers. This work presents a computer-aided diagnostic (CAD) system for the assessment of the severity of mitral regurgitation (MR) based on image processing that does not require the intervention... | ['Diagnosis, Computer-Assisted', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Image Processing, Computer-Assisted', 'Male', 'Mitral Valve Insufficiency', 'Severity of Illness Index', 'Ultrasonography'] | 27,127,894 | [['E01.158', 'L01.313.500.750.100.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['L01.224.308'], ['C14.280.484.461'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.520.308.980.438.475.364.500'], ['E01.370.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Autologous tumor vaccine lowering postsurgical recurrent rate of hepatocellular carcinoma. | BACKGROUND/AIMS: A tumor vaccine consisting of formalin-fixed hepatocellular carcinoma (HCC) tissue fragments, biodegradable sustained-releasers of granulocyte-macrophage-colony stimulating factor (GM-CSF) and interleukin-2 (IL-2), and an adjuvant was developed. The aim of this study was to evaluate the effects of auto... | ['Adolescent', 'Adult', 'Aged', 'Animals', 'Cancer Vaccines', 'Carcinoma, Hepatocellular', 'Cell Line, Tumor', 'Hepatectomy', 'Humans', 'Liver Neoplasms', 'Liver Neoplasms, Experimental', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Middle Aged', 'Neoplasm Metastasis', 'Neoplasm Recurrence, Local', 'Neoplasm Transplantation'... | 16,795,983 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['D20.215.894.200'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A11.251.210.190', 'A11.251.860.180'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623',... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Age-related changes in the cellular level of amylase and protein synthesis in the rat parotid gland. | Age-related changes in the cellular content of secretory proteins and protein synthesis were studied in parotid glands of rats of various ages. The secretory protein content (determined by measuring the level of alpha-amylase activity) and the synthesis of proteins (assayed by the rate of incorporation of 3H-leucine in... | ['Aging', 'Amylases', 'Animals', 'DNA', 'Leucine', 'Male', 'Parotid Gland', 'Rats', 'Salivary Proteins and Peptides', 'alpha-Amylases'] | 6,162,871 | [['G07.345.124'], ['D08.811.277.450.066'], ['B01.050'], ['D13.444.308'], ['D12.125.070.637', 'D12.125.142.441'], ['A03.556.500.760.464', 'A10.336.779.464', 'A14.549.760.464'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.644.848', 'D12.776.850'], ['D08.811.277.450.066.050']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The role of arginine metabolic pathway during embryogenesis and germination in maritime pine (Pinus pinaster Ait.). | Vegetative propagation through somatic embryogenesis is critical in conifer biotechnology towards multivarietal forestry that uses elite varieties to cope with environmental and socio-economic issues. An important and still sub-optimal process during in vitro maturation of somatic embryos (SE) is the biosynthesis and d... | ['Arginine', 'Germination', 'Metabolic Networks and Pathways', 'Pinus'] | 29,112,758 | [['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['G07.345.625.249', 'G15.357'], ['G03.493'], ['B01.650.940.800.575.912.625.875.777']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A modified protocol for generating the simulated weightlessness rat model]. | OBJECTIVE: To introduce a modified protocol for generating the simulated weightlessness rat model by hindlimb unloading.METHODS: Ninety male adult SD rats were randomly divided into three groups: the control group, classical suspension group and modified suspension group (n=30/group). In the classical suspension group,... | ['Animals', 'Hindlimb Suspension', 'Male', 'Muscle, Skeletal', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley', 'Weightlessness Simulation'] | 31,250,615 | [['B01.050'], ['E05.472.760.370', 'E05.977.400', 'N06.230.150.440.950.400'], ['A02.633.567', 'A10.690.552.500'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['E05.977', 'N06.230.150.44... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Long-term experiences following extracorporeal shockwave lithotripsy in patients with urinary calculi]. | A report is given on the experience we have had over a period of up to 7 years following ESWL treatment in urinary stone patients. 131I-hippuran clearance studies were conducted on 19 patients prior to and 6.6 years subsequent to ESWL. There was no evidence of any degree of deterioration in total renal function or of a... | ['Adult', 'Female', 'Follow-Up Studies', 'Humans', 'Iodohippuric Acid', 'Kidney Calculi', 'Kidney Calices', 'Lithotripsy', 'Male', 'Middle Aged', 'Recurrence', 'Ureteral Calculi', 'Urodynamics'] | 2,741,259 | [['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.277.431.579', 'D02.241.223.100.100.400.500', 'D02.241.755.360.579', 'D02.455.426.559.389.127.085.460.500'], ['C12.777.419.600.500', 'C12.777.967.249.500... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A population-based longitudinal study on work environmental factors and the risk of major depressive disorder. | To investigate the relation between work environmental factors and the risk of major depressive disorder (MDD) over 1 year, the authors conducted a population-based longitudinal study of randomly selected employees in Alberta, Canada (January 2008 to November 2011). Participants without a current or lifetime diagnosis ... | ['Adult', 'Aged', 'Alberta', 'Depressive Disorder, Major', 'Environment', 'Family', 'Female', 'Health Surveys', 'Humans', 'Incidence', 'Logistic Models', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Occupational Diseases', 'Psychological Tests', 'Risk Factors', 'Sex Factors', 'Stress, Psycho... | 22,556,191 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.107.567.176.064'], ['F03.600.300.375'], ['G16.500.275', 'N06.230'], ['F01.829.263', 'I01.880.853.150'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.59... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Anti-oligomeric single chain variable domain antibody differentially affects huntingtin and alpha-synuclein aggregates. | Huntington's and Parkinson's diseases are both neurodegenerative disorders caused at least in part by misfolding and aggregation of huntingtin (htt) and alpha-synuclein, respectively. Here we use a single chain antibody fragment (scFv) isolated against oligomeric alpha-synuclein to probe similarities and differences be... | ['Biopolymers', 'Humans', 'Huntingtin Protein', 'Immunoglobulin Fragments', 'Microscopy, Atomic Force', 'Nerve Tissue Proteins', 'Nuclear Proteins', 'alpha-Synuclein'] | 18,230,361 | [['D05.750.078', 'D25.720.099', 'J01.637.051.720.099'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.441'], ['D12.644.541.500', 'D12.776.124.486.485.680', 'D12.776.124.790.651.680', 'D12.776.377.715.548.680'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['D12.776.631'], ['D12.776.660'], ['D12.776.631.... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Myocardial protection during coronary surgery. Getting the maximum advantage of both cardioplegia and hypothermia. | The author presents a specially timed protocol of a combination of cold cardioplegic arrest and deep total body hypothermia designed to include the best features and to eliminate some of the principal short-comings of these 2 commonly used methods of myocardial preservation. According to this protocol, the operations w... | ['Heart Arrest, Induced', 'Humans', 'Hypothermia, Induced', 'Myocardial Revascularization', 'Time Factors'] | 6,180,517 | [['E04.100.376.374', 'E04.928.220.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.258.750'], ['E04.100.376.719', 'E04.928.220.520'], ['G01.910.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treatment for calcaneal malunion. | BACKGROUND: Pain, limping, and deformity are the most common complications following calcaneal malunion which results from non-operative treatment for calcaneal fractures.OBJECTIVE: To introduce the experience of treating calcaneal fracture malunion.METHOD: Between December 2009 and April 2011, eleven patients with cal... | ['Adult', 'Arthrodesis', 'Calcaneus', 'Fractures, Malunited', 'Humans', 'Male', 'Postoperative Complications', 'Treatment Outcome', 'Young Adult'] | 23,412,236 | [['M01.060.116'], ['E04.555.100'], ['A02.835.232.043.300.710.300'], ['C26.404.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.767'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Efficient and rapid nucleosome traversal by RNA polymerase II depends on a combination of transcript elongation factors. | The nucleosome is generally found to be a strong barrier to transcript elongation by RNA polymerase II (pol II) in vitro. The elongation factors TFIIF and TFIIS have been shown to cooperate in maintaining pol II in the catalytically competent state on pure DNA templates. We now show that although TFIIF or TFIIS alone i... | ['Animals', 'Histones', 'Humans', 'Nucleosomes', 'Point Mutation', 'RNA Polymerase II', 'Transcription Factors, TFII', 'Transcription, Genetic', 'Transcriptional Elongation Factors', 'Xenopus'] | 21,177,855 | [['B01.050'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.106.279.345.190.160.180.625', 'D12.776.664.224.550', 'G05.360.160.180.625'], ['G05.365.590.675'], ['D08.811.913.696.445.735.270.762'], ['D12.776.260.775.875', 'D12.776.930.930.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gallbladder perforation: risk factors and outcome. | BACKGROUND: Gallbladder perforation is difficult to diagnose and is associated with significant morbidity. This study investigates factors affecting outcome in patients with gallbladder perforation over two decades.MATERIALS AND METHODS: From 1982 to 2002 data from patients undergoing cholecystectomy at one institution... | ['Age Factors', 'Aged', 'Cholecystectomy', 'Cholecystitis', 'Cholelithiasis', 'Comorbidity', 'Female', 'Gallbladder Diseases', 'Gangrene', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prospective Studies', 'Risk Factors', 'Sex Factors'] | 16,412,466 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E04.210.120.172'], ['C06.130.564.263'], ['C06.130.409'], ['N05.715.350.225', 'N06.850.490.687'], ['C06.130.564'], ['C23.550.717.427'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E05.318.372.500.750.625', 'N05.7... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
25-Hydroxyvitamin D concentrations in dogs with naturally acquired blastomycosis. | BACKGROUND: Hypovitaminosis D is common in humans with tuberculosis, and adequate serum 25-hydroxyvitamin D [25(OH)D] concentrations may improve response to therapy. The pathomechanism of Blastomyces dermatitidis is similar to that of Mycobacterium tuberculosis, but the 25(OH)D status of dogs with blastomycosis has not... | ['Animals', 'Blastomycosis', 'Calcium', 'Case-Control Studies', 'Dog Diseases', 'Dogs', 'Female', 'Male', 'Parathyroid Hormone', 'Vitamin D'] | 30,079,575 | [['B01.050'], ['C01.150.703.302.055', 'C01.150.703.534.350', 'C01.748.435.395', 'C01.800.200.055', 'C08.381.472.350', 'C08.730.435.395', 'C17.800.838.208.055'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C22.268'], ['B01.050.15... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[The application of external fixation for the treatment of supracondylar femoral fracture after total knee replacement]. | OBJECTIVE: To explore the external fixation for treatment of supracondylar femoral fractures after total knee replacement.METHODS: From June 2005 to July 2007, 7 cases of supracondylar femoral fracture after total knee replacement were treated with external fixation included 4 males and 3 females with an average age of... | ['Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Knee', 'External Fixators', 'Female', 'Femoral Fractures', 'Fracture Fixation', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Recovery of Function', 'Treatment Outcome'] | 20,575,297 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['C26.404.061', 'C26.558.276'], ['E04.555.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['G16.757'], ['E01.789... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis of polyaniline nanoparticles and their application for the removal of Crystal Violet dye by ultrasonicated adsorption process based on Response Surface Methodology. | The present study focuses the synthesis of polyaniline nanoparticles (PANP) by rapid mixing polymerization method. They were recognized by FTIR and SEM techniques. Moreover they were utilized for the removal of Crystal Violet (CV) dye by ultrasonicated adsorption process. It ensures a quick alternative method compared ... | ['Adsorption', 'Aniline Compounds', 'Chemistry Techniques, Synthetic', 'Coloring Agents', 'Diffusion', 'Gentian Violet', 'Kinetics', 'Models, Theoretical', 'Nanoparticles', 'Nanotechnology', 'Ultrasonic Waves', 'Water Pollutants, Chemical'] | 27,773,286 | [['G01.030', 'G02.020'], ['D02.092.146'], ['E05.197', 'J01.897.836.249'], ['D27.720.233'], ['G01.202', 'G02.196'], ['D02.092.146.400'], ['G01.374.661', 'G02.111.490'], ['E05.599'], ['J01.637.512.600'], ['H01.603', 'J01.897.520.600'], ['G01.750.770.776.891'], ['D27.888.284.903.655']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Synapse-glia interactions are governed by synaptic and intrinsic glial properties. | It is believed that glial cell activation and their interactions with synapses are predominantly dependent upon the characteristics of synaptic activity and the level of transmitter release. Because synaptic properties vary from one type of synapse to another, synapse-glia interactions should differ accordingly. The go... | ['Acetylcholine', 'Animals', 'Calcium Signaling', 'Cell Communication', 'Male', 'Mice', 'Muscle Fibers, Fast-Twitch', 'Muscle Fibers, Slow-Twitch', 'Muscle, Skeletal', 'Neuromuscular Junction', 'Neuronal Plasticity', 'Presynaptic Terminals', 'Schwann Cells', 'Synapses', 'Synaptic Transmission'] | 20,188,148 | [['D02.092.211.111'], ['B01.050'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['G04.085'], ['B01.050.150.900.649.313.992.635.505.500'], ['A10.690.552.500.500.600', 'A11.620.249.400'], ['A10.690.552.500.500.700', 'A11.620.249.700'], ['A02.633.567', 'A10.690.552.500'], ['A08.800.550.550.550', 'A08.850... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of aeration on water quality from septic system leachfields. | We conducted a pilot-scale study at a research facility in southeastern Connecticut to assess the effects of leachfield aeration on removal of nutrients and pathogens from septic system effluent. Treatments consisted of lysimeters periodically aerated to maintain a headspace O(2) concentration of 0.209 mol mol(-1) (AIR... | ['Air', 'Biodegradation, Environmental', 'Engineering', 'Enterobacteriaceae', 'Nitrogen', 'Oxygen', 'Phosphorus', 'Quality Control', 'Solubility', 'Waste Disposal, Fluid'] | 15,356,244 | [['G16.500.275.063.150', 'N06.230.300.100.150'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['J01.293'], ['B03.440.450.425', 'B03.660.250.150'], ['D01.268.604', 'D01.362.625'], ['D01.268.185.550', 'D01.362.670'], ['D01.268.666'], ['J01.897.608'], ['G02.805'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.60... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1â production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis. | OBJECTIVE: The concept that intraarticular crystals of uric acid by themselves trigger episodes of painful gouty arthritis is inconsistent with the clinical reality. Patients with large deposits of monosodium urate monohydrate (MSU) crystals (tophi) do not necessarily experience gouty attacks. In fact, it is the excess... | ['Animals', 'Apoptosis Regulatory Proteins', 'Arthritis, Gouty', 'CARD Signaling Adaptor Proteins', 'Caspase 1', 'Cells, Cultured', 'Cytoskeletal Proteins', 'Enzyme-Linked Immunosorbent Assay', 'Fatty Acids', 'Humans', 'Inflammation', 'Interleukin-1beta', 'Knee Joint', 'Leukocytes, Mononuclear', 'Macrophages', 'Male', ... | 20,662,061 | [['B01.050'], ['D12.644.360.075', 'D12.776.476.075'], ['C05.550.114.423.410', 'C05.550.354.500.500', 'C05.799.414.410', 'C16.320.565.798.368.410', 'C18.452.648.798.368.410'], ['D12.644.360.024.131', 'D12.644.360.075.358', 'D12.776.157.057.006', 'D12.776.476.024.139', 'D12.776.476.075.358'], ['D08.811.277.656.262.500.12... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Pathomorphosis of personality changes in patients with epilepsy]. | Psychical features of 600 epileptic patients aged 5 to 40 were investigated in a long term clinical follow-up. Social changes, environmental factors, education faults had major effects on the patients. Classical personality traits were subject to a considerable pathomorphosis in these patients. Along with some positive... | ['Adolescent', 'Adult', 'Attitude to Health', 'Child', 'Child, Preschool', 'Epilepsy', 'Family', 'Humans', 'Neurocognitive Disorders', 'Personality Disorders', 'Social Environment'] | 2,781,943 | [['M01.060.057'], ['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['M01.060.406'], ['M01.060.406.448'], ['C10.228.140.490'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.615'], ['F03.675'], ['I01.880.853.500']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Ultrastructural changes of mast cells in the nasal mucosa in patients with pollinosis]. | The ultrastructural changes of mast cells in nasal mucosa taken from patients with pollinosis during pollen season were observed by electron microscopy. The main features of degranulation were as follows: 1. swelling of granules with lower electron density; 2. disappearance of the perigranular membrane; 3. vacuoles fou... | ['Humans', 'Mast Cells', 'Microscopy, Electron', 'Nasal Mucosa', 'Rhinitis, Allergic, Seasonal'] | 2,031,729 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.427', 'A15.382.652'], ['E01.370.350.515.402', 'E05.595.402'], ['A04.531.520', 'A04.760.600', 'A10.615.550.760.600'], ['C08.460.799.315.750', 'C08.674.453.750', 'C09.603.799.315.750', 'C20.543.480.680.443.750']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Residual amounts of glycoprotein Ib concomitant with near-absence of glycoprotein IX in platelets of Bernard-Soulier patients. | A study of the Bernard-Soulier syndrome in two unrelated families using different polyclonal antibodies in a sensitive immunoblot assay showed residual amounts of platelet membrane glycoprotein (GP) lb in the eight homozygotes, as well as the near-absence of GPlb beta and GPIX. The eight heterozygotes studied showed a ... | ['Bernard-Soulier Syndrome', 'Blood Platelet Disorders', 'Blood Platelets', 'Homozygote', 'Humans', 'Immunoassay', 'Pedigree', 'Platelet Membrane Glycoproteins'] | 3,416,070 | [['C15.378.100.100.080', 'C15.378.140.120', 'C15.378.463.080', 'C16.320.099.080'], ['C15.378.140'], ['A11.118.188', 'A15.145.229.188'], ['G05.380.554'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['E05.393.673'], ['D12.776.395.550.625', 'D12.776.543.550.625', 'D12.776.543.750.705.6... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recovery and kinetic characteristics of desflurane and sevoflurane in volunteers after 8-h exposure, including kinetics of degradation products. | BACKGROUND: Desflurane and sevoflurane permit speedier changes in anesthetic partial pressures than do older halogenated anesthetics. The authors determined the kinetic characteristics of desflurane and sevoflurane and those of compound A [CH2F-O-C(=CF2)(CF3)], a nephrotoxic degradation product of sevoflurane.METHODS: ... | ['Anesthetics, Inhalation', 'Desflurane', 'Ethers', 'Humans', 'Hydrocarbons, Fluorinated', 'Isoflurane', 'Male', 'Methyl Ethers', 'Sevoflurane', 'Time Factors'] | 9,316,955 | [['D27.505.696.277.100.035.060', 'D27.505.954.427.210.100.035.060'], ['D02.355.417.166', 'D02.355.601.325', 'D02.455.526.510.213'], ['D02.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.526.510'], ['D02.355.601.570'], ['D02.355.601'], ['D02.355.601.810', 'D02.455.526.510.717'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The relationship between serum biotin and oxidant/antioxidant activities in bovine lameness. | Serum biotin concentrations, erythrocyte superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), reduced glutathione (GSH) and plasma thiobarbituric acid reactive substances (TBARS) were measured in 36 dairy cows, 18 of them were healthy and served as control. In the 18 cows with lameness problems,... | ['Animals', 'Antioxidants', 'Biotin', 'Case-Control Studies', 'Catalase', 'Cattle', 'Cattle Diseases', 'Female', 'Fibrinogen', 'Glutathione', 'Glutathione Peroxidase', 'Lameness, Animal', 'Oxidative Stress', 'Superoxide Dismutase', 'Thiobarbituric Acid Reactive Substances'] | 21,074,230 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D03.383.129.308.080', 'D08.211.096'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D08.811.682.732.332'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['D12.776.124.050.250', 'D12.776.124.125.500'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Ultrastructure of the mitotic nuclei in Leishmania mexicana ssp. Tridimensional reconstruction of the mitotic spindle and dense plaques]. | The ultrastructure of mitotic nuclei of the promastigote Leishmania mexicana ssp. was studied by serial thin sections and three-dimensional reconstructions of each divisional stage. At the beginning of nuclear division (equatorial stage), a set of six dense plaques located about the equatorial region of the nucleus and... | ['Animals', 'Leishmania mexicana', 'Mitosis', 'Spindle Apparatus'] | 3,222,496 | [['B01.050'], ['B01.268.475.868.488.410'], ['G04.144.220.220.781', 'G05.113.220.781'], ['A11.284.430.214.190.750.820']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of the p53 homologue p63alpha and deltaNp63alpha in normal and neoplastic cells. | A burgeoning family of p53-related genes have been described recently, including p73 and p63. Both these genes encode proteins with many similarities to p53 but also with the potential for forming a range of related species by alternative promoter usage and alternative splicing. In order to begin the characterization o... | ['Amino Acid Sequence', 'Blood Proteins', 'Blotting, Western', 'Cell Division', 'DNA-Binding Proteins', 'Genes, Tumor Suppressor', 'Humans', 'Immune Sera', 'Membrane Proteins', 'Mitomycin', 'Molecular Sequence Data', 'Neoplasm Proteins', 'Nerve Tissue Proteins', 'Organ Specificity', 'Peptide Fragments', 'Phosphoprotein... | 10,657,951 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.124'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D12.776.260'], ['G05.360.340.024.340.375.249', 'G05.360.340.024.340.415.400'], ['... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Ions Modulate Stress-Induced Nanotexture in Supported Fluid Lipid Bilayers. | Most plasma membranes comprise a large number of different molecules including lipids and proteins. In the standard fluid mosaic model, the membrane function is effected by proteins whereas lipids are largely passive and serve solely in the membrane cohesion. Here we show, using supported 1,2-dioleoyl-sn-glycero-3-phos... | ['Anti-Infective Agents', 'Calcium Chloride', 'Glycerylphosphorylcholine', 'Ions', 'Lipid Bilayers', 'Microscopy, Atomic Force', 'Nanostructures', 'Phosphatidylcholines', 'Potassium Chloride', 'Sodium Chloride', 'Stress, Mechanical', 'Surface Properties', 'Temperature', 'Tromethamine'] | 28,746,853 | [['D27.505.954.122'], ['D01.146.300', 'D01.210.450.150.150'], ['D02.033.800.875.750.449', 'D09.853.875.750.449', 'D10.570.755.375.760.400.386', 'D10.570.755.375.760.400.800.806.500'], ['D01.248.497'], ['D10.570.510', 'J01.637.087.500.510'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['J01.637.512'], ['D10.570.755.... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Effortful control, exposure to community violence, and aggressive behavior: Exploring cross-lagged relations in adolescence. | Self-regulation processes and violent contexts play an important role in predicting adolescents' aggressive behavior; less clear is how all three constructs are linked to each other over time. The present study examined the longitudinal relations among adolescents' self-reported effortful control (EC), exposure to comm... | ['Adolescent', 'Adolescent Behavior', 'Aggression', 'Child', 'Female', 'Humans', 'Italy', 'Male', 'Residence Characteristics', 'Risk Factors', 'Violence'] | 28,603,851 | [['M01.060.057'], ['F01.145.022'], ['F01.145.126.125', 'F01.145.813.045'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['N01.224.791', 'N06.850.505.400.800'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Faunistic analysis of sharpshooters (Hemiptera: Auchenorrhyncha, Cicadellidae) in a 'Westin' sweet orange orchard. | The purpose of this study was to analyze sharpshooter fauna in a five-year-old 'Westin' sweet orange orchard. Yellow sticky traps were placed on the edge of a forest, and on the periphery and inside the citrus stand. The traps were evaluated fortnightly, for three years. The most frequent species were Acrogonia citrina... | ['Animals', 'Brazil', 'Citrus sinensis', 'Hemiptera', 'Insect Vectors', 'Population Density', 'Seasons', 'Species Specificity'] | 18,813,748 | [['B01.050'], ['Z01.107.757.176'], ['B01.650.940.800.575.912.250.875.177.769'], ['B01.050.500.131.617.412'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['N01.224.600', 'N06.850.505.400.600'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['G16.824']] | ['Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Cloning of a gene encoding a lupus-associated human autoantibody VK region using the polymerase chain reaction and degenerate primers. | The variable light-chain-encoding gene of a human autoantibody secreted by a B-cell hybridoma derived from a patient with systemic lupus erythematosus was amplified using the polymerase chain reaction and degenerate primers. After cloning, the nucleotide sequence of the EcoRI-HindIII region was determined. It is highly... | ['Autoantibodies', 'Base Sequence', 'Cell Line', 'Cloning, Molecular', 'Humans', 'Immunoglobulin Variable Region', 'Immunoglobulin kappa-Chains', 'Lupus Erythematosus, Systemic', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Sequence Homology, Nucleic Acid'] | 1,905,262 | [['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['E05.393.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.541.500.650.500', 'D12.776.124.486.485.680.650.500', 'D12.776.124.486.48... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Total synthesis of (+/-)-kellermanoldione: stepwise cycloaddition of a functionalized diene and allenoate. | The total synthesis of the diterpene kellermanoldione 1 is reported. Stepwise [4 + 2] cycloaddition of the ketal diene 8 and the allenoate 3 afforded the exo adduct 10x as the major product. It was converted into 1 via six steps, among them a key nonconjugative hydrolysis of a gamma-methylene silyl enol ether. | ['Catalysis', 'Cyclization', 'Diterpenes', 'Molecular Structure', 'Plants, Medicinal', 'Polyenes', 'Stereoisomerism'] | 19,655,733 | [['G02.130'], ['G02.111.180', 'G02.607.133', 'G03.208'], ['D02.455.849.291'], ['G02.111.570', 'G02.466'], ['B01.650.560'], ['D02.455.326.271.665'], ['G02.607.445.682']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Magnetic carbon nanotube modified with polymeric deep eutectic solvent for the solid phase extraction of bovine serum albumin. | This article described the fabrication of novel magnetic carbon nanotube modified with polymeric deep eutectic solvent (M-CNT@PDES) and its application as extractant for the magnetic solid phase extraction (MSPE) of bovine serum albumin (BSA). The physicochemical properties and morphology of M-CNT@PDES were characteriz... | ['Animals', 'Cattle', 'Electrophoresis, Polyacrylamide Gel', 'Limit of Detection', 'Magnetic Phenomena', 'Nanotubes, Carbon', 'Quaternary Ammonium Compounds', 'Serum Albumin, Bovine', 'Solid Phase Extraction', 'Solvents', 'Xylitol'] | 31,514,903 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.401.402', 'E05.301.300.319'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['G01.358'], ['D01.268.150.250.500', 'J01.637.512.850.500'], ['D01.625.062.500', 'D02.092.877', 'D02.675.276'], ['D12.776.034.841.540', 'D12.776.1... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
High frequency of thyroid dysfunction in patients with vitiligo. | An association between vitiligo and autoimmune thyroid disease has previously been suspected. This study was undertaken to determine the frequency and type of thyroid disease in 35 consecutive patients admitted because of vitiligo compared with a matched control group. One or more signs of thyroid disease was demonstra... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Autoantibodies', 'Autoimmune Diseases', 'Female', 'Goiter', 'Graves Disease', 'Humans', 'Iodide Peroxidase', 'Male', 'Middle Aged', 'Thyroid Diseases', 'Thyroiditis, Autoimmune', 'Vitiligo'] | 7,911,617 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['C20.111'], ['C19.874.283'], ['C11.675.349.500', 'C19.874.283.605', 'C19.874.397.370', 'C20.111.555'], ['B01.050.150.900.649.313.988.400.112.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Expectations from the TraumaNetwork DGU®: Which goals have been achieved? What can be improved?]. | INTRODUCTION: Following the establishment of the first trauma networks in 2009 an almost nationwide certification could be achieved. Despite the impressive number of 46 certified networks, little is known about the actual improvements and the satisfaction of the participating hospitals.OBJECTIVES: This article aims to ... | ['Germany', 'Hospital Administration', 'Hospitals', 'Humans', 'Interinstitutional Relations', 'Organizational Objectives', 'Orthopedics', 'Traumatology', 'Wounds and Injuries'] | 25,135,704 | [['Z01.542.315'], ['H02.309', 'N02.278.216.500', 'N04.452.442.452'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.822.400'], ['N04.452.615'], ['H02.403.810.494'], ['H02.403.810.850'], ['C26']] | ['Geographicals [Z]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Evidence that processing of ribonucleotides in DNA by topoisomerase 1 is leading-strand specific. | Ribonucleotides incorporated during DNA replication are removed by RNase H2-dependent ribonucleotide excision repair (RER). In RER-defective yeast, topoisomerase 1 (Top1) incises DNA at unrepaired ribonucleotides, initiating their removal, but this is accompanied by RNA-DNA-damage phenotypes. Here we show that these ph... | ['DNA', 'DNA Polymerase II', 'DNA Repair', 'DNA Replication', 'DNA Topoisomerases, Type I', 'Ribonucleotides', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins'] | 25,751,426 | [['D13.444.308'], ['D08.811.913.696.445.308.300.230'], ['G02.111.222', 'G05.219'], ['G02.111.225', 'G05.226'], ['D08.811.399.403.483', 'D12.776.157.687.375', 'D12.776.660.720.375'], ['D13.695.827'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12.776.354.750']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A soil actinobacterium scavenges atmospheric H2 using two membrane-associated, oxygen-dependent [NiFe] hydrogenases. | In the Earth's lower atmosphere, H2 is maintained at trace concentrations (0.53 ppmv/0.40 nM) and rapidly turned over (lifetime ? 2.1 y(-1)). It is thought that soil microbes, likely actinomycetes, serve as the main global sink for tropospheric H2. However, no study has ever unambiguously proven that a hydrogenase can ... | ['Atmosphere', 'Chromatography, Gas', 'Hydrogen', 'Hydrogenase', 'Mycobacterium smegmatis', 'Oxidation-Reduction', 'Oxygen', 'Soil Microbiology'] | 24,591,586 | [['G16.500.275.063', 'N06.230.300.100'], ['E05.196.181.349'], ['D01.268.406', 'D01.362.340'], ['D08.811.682.400'], ['B03.510.024.962.500.720.662', 'B03.510.460.400.410.552.552.720.662'], ['G02.700', 'G03.295.531'], ['D01.268.185.550', 'D01.362.670'], ['H01.158.273.540.274.555', 'N06.850.425.300']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Direct One-Step Fluorescent Labeling of O-GlcNAc-Modified Proteins in Live Cells Using Metabolic Intermediates. | The modification of proteins with O-linked N-acetylglucosamine ( O-GlcNAc) by the enzyme O-GlcNAc transferase (OGT) has emerged as an important regulator of cellular physiology. Metabolic labeling strategies to monitor O-GlcNAcylation in cells have proven of great value for uncovering the molecular roles of O-GlcNAc. T... | ['Acetylglucosamine', 'Fluorescence', 'Glycosylation', 'HeLa Cells', 'Humans', 'Molecular Structure', 'N-Acetylglucosaminyltransferases'] | 30,296,064 | [['D09.067.342.531.050'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570', 'G02.466'], ['D08.811.913.400.100.250']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spectral analysis and high-performance liquid chromatography of the cis-trans geometrical isomers of 5,6-Epoxyretinal. | Spectral characterization of 5,6-epoxyretinal isomers (II) prepared by a regioselective epoxidation of the parent retinal isomers have been described. High-performance liquid chromatographic separation of epoxyretinals and a photoisomerization behavior of all-trans-5,6-epoxyretinals (IIa) have been investigated. | ['Chromatography, High Pressure Liquid', 'Magnetic Resonance Spectroscopy', 'Photochemistry', 'Retinaldehyde', 'Spectrophotometry, Ultraviolet', 'Stereoisomerism', 'Vitamin A'] | 6,886,834 | [['E05.196.181.400.300'], ['E05.196.867.519'], ['H01.181.529.711'], ['D02.047.850', 'D02.455.326.271.665.202.495.690', 'D02.455.426.392.368.367.379.249.700.690', 'D02.455.849.131.495.690', 'D02.455.849.291.605', 'D23.767.261.700.690'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['G02.607.445.682'], ['D02.455.326.2... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Localization of gene expression of calbindin in the brain of adult rats. | Localization of gene expression of calbindin, a cytosolic calcium-binding protein, was examined throughout the adult rat brain by in situ hybridization with cDNA probes. The gene was expressed most intensely in the Purkinje cells in the cerebellum, intensely in the granule cells of the dentate gyrus, and moderately in ... | ['Animals', 'Brain', 'Calbindins', 'Gene Expression', 'Histocytochemistry', 'Male', 'Nucleic Acid Hybridization', 'RNA, Messenger', 'Rats', 'Rats, Inbred Strains', 'S100 Calcium Binding Protein G', 'Tissue Distribution'] | 1,608,531 | [['B01.050'], ['A08.186.211'], ['D12.776.157.125.090'], ['G05.297'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['E05.393.661', 'G02.111.611'], ['D13.444.735.544'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Brachial plexus meningioma, report of a case with immunohistochemical and ultrastructural examination. | Peripheral nerve meningiomas are exceedingly rare neoplasms of controversial origin; only four cases have been reported. Proposed origins of ectopic meningiomas include extradural trapping of arachnoid cells during embryogenesis, ectopic migration of arachnoid cell nests with the developing peripheral nerve, and metapl... | ['Brachial Plexus', 'Female', 'Humans', 'Immunohistochemistry', 'Meningioma', 'Middle Aged', 'Peripheral Nervous System Neoplasms'] | 2,711,832 | [['A08.800.800.720.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['C04.557... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Complex-irreversibility and evolution. | Both, irreversibility and evolution, imply order in time. It is argued that the only possible concept of time is a 'system-specific time', and that order in time is convertible into order in space and vice-versa. While life-less, complex systems are irreversible because of their complexity and, hence, not repeatable, l... | ['Animals', 'Base Sequence', 'Biological Evolution', 'DNA Replication', 'DNA, Single-Stranded', 'Genetic Code', 'Genetic Variation', 'Models, Genetic', 'Repetitive Sequences, Nucleic Acid'] | 6,873,230 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045', 'G16.075'], ['G02.111.225', 'G05.226'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['G05.360.335'], ['G05.365'], ['E05.599.395.397'], ['G02.111.570.080.708', 'G05.360.080.708']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A disposition kinetic study of Tramadol in bile duct ligated rats in perfused rat liver model. | Tramadol hydrochloride is a centrally acting synthetic opioid analgesic drug and is used to treat chronic pain. In this study, the effects of Bile Duct Ligation (BDL) on the pharmacokinetics of tramadol in a liver recirculating perfusion system of male rats were used. Twenty-four Wistar male rats were randomly divided ... | ['Animals', 'Bile Ducts', 'Disease Models, Animal', 'Kinetics', 'Ligation', 'Liver', 'Male', 'Perfusion', 'Rats, Wistar', 'Tramadol'] | 28,460,228 | [['B01.050'], ['A03.159.183'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G01.374.661', 'G02.111.490'], ['E04.426'], ['A03.620'], ['E05.680'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D02.033.415.510.500.802', 'D02.092.668.387.750', 'D10.289.510.500.802']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microstructural Evaluation of Contaminated Implant Surface Treated by Laser, Photodynamic Therapy, and Chlorhexidine 2 percent. | PURPOSE: Decontamination of the rough surfaces of dental implants is a challenge in the treatment of peri-implantitis. An acceptable cleaning technique must be able to debride and detoxify the surface without traumatizing it. This study assessed the possible implant surface alterations following decontamination with la... | ['Aggregatibacter actinomycetemcomitans', 'Anti-Infective Agents, Local', 'Biofilms', 'Chlorhexidine', 'Coloring Agents', 'Decontamination', 'Dental Implants', 'Humans', 'Indocyanine Green', 'Lasers, Semiconductor', 'Lasers, Solid-State', 'Microscopy, Electron, Scanning', 'Peri-Implantitis', 'Photochemotherapy', 'Photo... | 30,231,087 | [['B03.440.450.600.224.500', 'B03.660.250.550.170.500'], ['D27.505.954.122.187'], ['A20.593', 'G06.120'], ['D02.078.370.141.100'], ['D27.720.233'], ['N06.850.780.325'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.400'], ['E... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Isolated follicle-stimulating hormone deficiency in a woman with X chromosomal mosaicism. | Primary amenorrhea was observed in a 40-year-old woman with a proportionate female habitus. Serum levels of luteinizing hormone (LH) (71 to 97 mIU/ml) and estradiol (less than 10 pg/ml) were in the postmenopausal range, while follicle-stimulating hormone (FSH) remained at the lower limit of detection (1 to 6 mIU/ml). L... | ['Adult', 'Amenorrhea', 'Estradiol', 'Female', 'Follicle Stimulating Hormone', 'Glucose Tolerance Test', 'Humans', 'Luteinizing Hormone', 'Mosaicism', 'X Chromosome'] | 6,814,256 | [['M01.060.116'], ['C23.550.568.500'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Alexithymia explains increased empathic personal distress in individuals with and without eating disorders. | It is often assumed that empathy impairments are common in individuals with eating disorders (EDs), but empirical work has been limited and produced mixed results, making the clinical features and treatment needs of this population difficult to determine. Alexithymia, characterised by difficulties identifying and descr... | ['Adult', 'Affective Symptoms', 'Diagnostic and Statistical Manual of Mental Disorders', 'Emotional Intelligence', 'Empathy', 'Feeding and Eating Disorders', 'Female', 'Humans', 'Male', 'Psychological Distress', 'Psychological Techniques'] | 30,428,774 | [['M01.060.116'], ['F01.145.126.100'], ['L01.453.245.945.200'], ['F01.752.543.500'], ['F01.752.355', 'F01.752.543.500.500'], ['F03.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.470.315'], ['E05.796', 'F04.669']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
[Theoretical conformational analysis of a encephalitogenic peptide molecule and a study of the structure-activity relationship in a series of its analogs]. | Semi-empirical energy calculations are used to determine all low-energy conformations of Trp-containing fragment 113-121 of myelin basic protein (experimental allergic encephalomyelitis inducing peptide). The computed conformations are compared with the results of physico-chemical experiments and data on biological tes... | ['Animals', 'Encephalomyelitis, Autoimmune, Experimental', 'Myelin Basic Protein', 'Peptides', 'Protein Conformation', 'Structure-Activity Relationship', 'Tryptophan'] | 2,475,178 | [['B01.050'], ['C10.114.703.300', 'C10.228.140.695.562.250', 'C10.314.350.250', 'C20.111.258.625.300', 'E05.598.500.500.500'], ['D12.776.543.620.540', 'D12.776.631.580.510'], ['D12.644'], ['G02.111.570.820.709'], ['G02.111.830', 'G07.690.773.997'], ['D12.125.072.050.850', 'D12.125.142.875']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impaired renal sensory responses after renal ischemia in the rat. | Renal sensory responses and reflex function were examined in rats 24 h after 45 min of ischemic injury caused by unilateral renal arterial occlusion (RAO). The integrity of renal pelvic mechanoreceptor (MRu)-mediated renorenal reflex was examined. An increase in ipsilateral afferent renal nerve activity (ARNA) and a re... | ['Animals', 'Arrestins', 'Female', 'Immunoblotting', 'Ischemia', 'Kidney', 'Kidney Diseases', 'Kidney Pelvis', 'Mechanoreceptors', 'Neprilysin', 'Nervous System', 'Physical Stimulation', 'RNA, Messenger', 'Rats', 'Rats, Wistar', 'Receptors, Neurokinin-1', 'Reflex', 'Renal Circulation', 'Sensation Disorders', 'Sodium Ch... | 12,089,383 | [['B01.050'], ['D12.644.360.024.098', 'D12.776.157.057.005', 'D12.776.306.090', 'D12.776.476.024.104', 'D12.776.543.090'], ['E05.478.566.320', 'E05.601.470.320'], ['C23.550.513'], ['A05.810.453'], ['C12.777.419', 'C13.351.968.419'], ['A05.810.453.537'], ['A08.675.650.915.750', 'A08.800.950.750', 'A11.671.650.915.750'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Edible alginate-based coating as carrier of antimicrobials to improve shelf-life and safety of fresh-cut melon. | The effect of malic acid and essential oils (EOs) of cinnamon, palmarosa and lemongrass and their main active compounds as natural antimicrobial substances incorporated into an alginate-based edible coating on the shelf-life and safety of fresh-cut "Piel de Sapo" melon (Cucumis melo L.) was investigated. Melon pieces (... | ['Alginates', 'Colony Count, Microbial', 'Consumer Product Safety', 'Cucurbitaceae', 'Food Contamination', 'Food Preservation', 'Food Preservatives', 'Glucuronic Acid', 'Hexuronic Acids', 'Humans', 'Malates', 'Oils, Volatile', 'Salmonella enteritidis', 'Time Factors'] | 18,164,505 | [['D09.698.068'], ['E01.370.225.875.220', 'E05.200.875.220'], ['N06.850.210'], ['B01.650.940.800.575.912.250.300'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['J01.576.423.850.700'], ['D27.720.372.300.385', 'G07.203.300.514.500.700', 'J02.500.514.500.700'], ['D02.241.081.844.915.162.249... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Blood oxygen saturation in various regions of the circulatory system in healthy persons]. | The gaseous composition of the blood has been determined in cardiac cavities and major vessels in 180 practically healthy individuals aged from 1 to 30 years, during diagnostic catheterization of the heart. Physiological norms of gaseous composition of the blood in cardiac cavities and in the major blood vessels have b... | ['Adolescent', 'Adult', 'Aged', 'Arteries', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Oxygen', 'Oxyhemoglobins', 'Reference Values', 'Veins'] | 7,154,507 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A07.015.114'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['D01.268.185.550', 'D01.362.670'], ['D12.776.124.400.707', 'D12.776.422.316.762.687'], ['E05.978.810'], ['A07.015.908']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Enzymes of the antioxidant network as novel determiners of Trypanosoma cruzi virulence. | Virulence of Trypanosoma cruzi depends on a variety of genetic and biochemical factors. It has been proposed that components of the parasites' antioxidant system may play a key part in this process by pre-adapting the pathogen to the oxidative environment encountered during host cell invasion. Using several isolates (1... | ['Animals', 'Antioxidants', 'Chagas Disease', 'Disease Models, Animal', 'Male', 'Mice', 'Trypanosoma cruzi', 'Virulence', 'Virulence Factors'] | 19,505,468 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C01.610.752.300.900.200', 'C01.920.625'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.268.475.868.887.140'], ['G06.930'], ['D23.946.896']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The study on clinical value of the detection about serum and Unconjugated Bilirubin in diagnosis of neonatal jaundice. | In this paper, the clinical value of the detection about serum and unconjugated bilirubin (UCB) in neonatal jaundice was studied to found an effective and rapid method for diagnose of neonatal jaundice. ALB (Serum Albumin), total serum bilirubin (TSB) and UCB were detected by ELISA method among the 100 cases with neona... | ['Bilirubin', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Infant, Newborn', 'Jaundice', 'Jaundice, Neonatal', 'Jaundice, Obstructive', 'Male', 'Predictive Value of Tests', 'Serum Albumin'] | 27,005,510 | [['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C23.550.429.500', 'C23.888.8... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The structure-activity relationship between polysaccharides from Sargassum thunbergii and anti-tumor activity. | Polysaccharides derived from Sargassum thunbergii were prepared to investigate the structure-activity relationship between polysaccharides and anti-tumor activity in vitro. Many factors were examined. Overall, STW (polysaccharide extracted by hot water) had the best activity, followed by STJ (polysaccharide extracted b... | ['A549 Cells', 'Antineoplastic Agents', 'Cell Survival', 'Humans', 'Molecular Weight', 'Polysaccharides', 'Sargassum', 'Structure-Activity Relationship', 'Sulfates', 'Uronic Acids'] | 28,716,753 | [['A11.251.210.190.080', 'A11.251.860.180.080', 'A11.436.054'], ['D27.505.954.248'], ['G04.346'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.494'], ['D09.698'], ['B01.750.600.725'], ['G02.111.830', 'G07.690.773.997'], ['D01.248.497.158.845', 'D01.875.800.800.850'], ['D02.241.081.844.915', 'D02.241.152.811',... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immune complexes in experimental alveolar hydatidosis. | Increasing amounts of immune complexes (IC) accumulated in the blood of C57BL/6J (H-2b) mice infected for 16 weeks with alveolar hydatid cysts. The circulating IC were detected both quantitatively (precipitation with 3.75% polyethylene glycol) and qualitatively (Raji cell binding assay) in the sera of hydatid-mice. The... | ['Animals', 'Antigen-Antibody Complex', 'Complement C3', 'Echinococcosis, Pulmonary', 'Echinococcus', 'Glomerulonephritis', 'Immune Complex Diseases', 'Immunoglobulin G', 'Immunoglobulin M', 'Kidney Glomerulus', 'Larva', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Pulmonary Alveoli'] | 6,227,116 | [['B01.050'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['D12.776.124.050.140', 'D12.776.124.486.274.250'], ['C01.610.335.190.396.480', 'C01.610.582.314', 'C01.748.450.314', 'C08.381.517.314', 'C08.730.450.314'], ['B01.050.500.500.736.215.327'], ['C12.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Documenting patient refusals. | Patient morbidity and mortality, subsequent to either patient- or provider-initiated refusals, are noteworthy. It has been estimated that hospital admission is twice as likely after prehospital providers refuse a patient transportation to the hospital. In one particular study group, prehospital-provider refusal of tran... | ['Documentation', 'Emergency Medical Services', 'Humans', 'Informed Consent', 'Liability, Legal', 'Mental Competency', 'Treatment Refusal', 'United States'] | 11,383,168 | [['L01.453.245'], ['N02.421.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.473.650.718', 'I01.880.604.583.427', 'N03.706.437.650.312', 'N03.706.535.489'], ['I01.880.604.583.490', 'N03.706.535.547'], ['F01.590', 'F02.410', 'I01.880.604.583.530', 'N03.706.535.625'], ['F01.100.150.750.750', 'F01.145... | ['Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Density and shape as CT predictors of intracerebral hemorrhage growth. | BACKGROUND AND PURPOSE: Intracerebral hemorrhage (ICH) growth predicts mortality and functional outcome. We hypothesized that irregular hematoma shape and density heterogeneity, reflecting active, multifocal bleeding or a variable bleeding time course, would predict ICH growth.METHODS: Three raters examined baseline su... | ['Cerebral Hemorrhage', 'Disease Progression', 'Factor VIIa', 'Hematoma', 'Humans', 'Image Processing, Computer-Assisted', 'Predictive Value of Tests', 'Recombinant Proteins', 'Tomography, X-Ray Computed'] | 19,286,590 | [['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['C23.550.291.656'], ['D08.811.277.656.300.760.300', 'D08.811.277.656.959.350.300', 'D12.776.124.125.325.300', 'D23.119.325.300'], ['C23.550.414.838'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E05.318.370.800.650', 'N... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Risk factors for positioning-related somatosensory evoked potential changes in 3946 spinal surgeries. | The goal of this study was to evaluate the risk factors associated with positioning-related SSEP changes (PRSC). The study investigated the association between 18 plausible risk factors and the occurrence of intraoperative PRSC. Risk factors investigated included demographic variables, comorbidities, and procedure rela... | ['Aged', 'Aged, 80 and over', 'Evoked Potentials, Somatosensory', 'Female', 'Hemodynamic Monitoring', 'Humans', 'Intraoperative Period', 'Male', 'Middle Aged', 'Monitoring, Intraoperative', 'Multivariate Analysis', 'Neurosurgical Procedures', 'Retrospective Studies', 'Risk Factors', 'Spine'] | 29,855,850 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.265.216.500.400', 'G11.561.200.500.400'], ['E01.370.370.428', 'E01.370.520.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374', 'N02.421.585.753.374'], ['M01.060.116.630'], ['E01.370.520.510', 'E04.510'], ['E05.318.740.150.500', 'N05.715.360.750.12... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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