Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Physical and functional interactions between protein tyrosine phosphatase alpha, PI 3-kinase, and PKCdelta. | The somatostatin analogue, TT-232 inhibits cell proliferation and induces apoptosis in a variety of tumor cells both in vivo and in vitro. While the early transient activation of Erk/MAPK was found to be important for the induction of cell cycle arrest, the signaling pathway leading to the activation of Erk/MAPK had no... | ['Animals', 'Antineoplastic Agents', 'COS Cells', 'Cells, Cultured', 'Enzyme Activation', 'GTP-Binding Proteins', 'Genes, src', 'Heterogeneous-Nuclear Ribonucleoprotein Group F-H', 'Humans', 'Isoenzymes', 'Mitogen-Activated Protein Kinases', 'Peptides, Cyclic', 'Phosphatidylinositol 3-Kinases', 'Phosphorylation', 'Prot... | 11,676,480 | [['B01.050'], ['D27.505.954.248'], ['A11.251.210.172.500', 'A11.329.228.220'], ['A11.251'], ['G02.111.263', 'G03.328'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['G05.360.340.024.340.375.500.791.570'], ['D12.776.157.725.813.750.400', 'D12.776.664.962.813.750.400'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mutational analysis of the U12-dependent branch site consensus sequence. | Highly conserved sequences at the 5' splice site and branch site of U12-dependent introns are important determinants for splicing by U12-dependent spliceosomes. This study investigates the in vivo splicing phenotypes of mutations in the branch site consensus sequence of the U12-dependent intron F from a human NOL1 (P12... | ['Alternative Splicing', 'Base Sequence', 'Consensus Sequence', 'Humans', 'Introns', 'Mutation', 'Nuclear Proteins', 'RNA Splice Sites', 'RNA, Small Nuclear', 'Spliceosomes', 'tRNA Methyltransferases'] | 18,824,513 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.580.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'], ['G05.365.590'], ['D12.776.660'], ['D13.444.735.544.550', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Metabolite normalization with local radiotherapy following breast tumor resection. | The aims of this study were to investigate changes in energy balance-associated metabolites associated with radiotherapy in patients with breast cancer, and to relate these changes to the clinical and pathological response-to-treatment. We studied 151 women with breast cancer who received radiotherapy following surgica... | ['Adult', 'Aged', 'Aged, 80 and over', 'Amino Acids', 'Citric Acid Cycle', 'Female', 'Glycolysis', 'Humans', 'Middle Aged', 'Triple Negative Breast Neoplasms'] | 30,444,915 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.125'], ['G02.111.165', 'G03.295.342', 'G03.493.170'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.180.788', 'C17.800.090.500.788']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Optimal designs of an HA-based DNA vaccine against H7 subtype influenza viruses. | The outbreak of a novel H7N9 influenza virus in 2013 has raised serious concerns for the potential of another avian-source pandemic influenza. Effective vaccines against H7N9 virus are important in the prevention and control of any major outbreak. Novel vaccination technologies are useful additions to existing approach... | ['Animals', 'Antibodies, Neutralizing', 'Antibodies, Viral', 'Enzyme-Linked Immunosorbent Assay', 'Hemagglutinin Glycoproteins, Influenza Virus', 'Humans', 'Influenza A Virus, H7N7 Subtype', 'Influenza A Virus, H7N9 Subtype', 'Influenza Vaccines', 'Influenza, Human', 'Neutralization Tests', 'Rabbits', 'Vaccines, DNA'] | 25,424,804 | [['B01.050'], ['D12.776.124.486.485.114.244', 'D12.776.124.790.651.114.244', 'D12.776.377.715.548.114.244'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
European Federation of Neurological Societies/Peripheral Nerve Society guideline on management of paraproteinaemic demyelinating neuropathies: report of a joint task force of the European Federation of Neurological Societies and the Peripheral Nerve Society. | BACKGROUND: Paraprotein-associated neuropathies have heterogeneous clinical, neurophysiological, neuropathological and haematological features. Objectives. To prepare evidence-based and consensus guidelines on the clinical management of patients with both a demyelinating neuropathy and a paraprotein (paraproteinaemic d... | ['Advisory Committees', 'Cooperative Behavior', 'Demyelinating Diseases', 'Europe', 'Evidence-Based Medicine', 'Humans', 'MEDLINE', 'Neurology', 'Paraproteinemias', 'Peripheral Nerves', 'Practice Guidelines as Topic', 'Societies, Medical'] | 16,879,290 | [['N03.706.742.500'], ['F01.145.813.115'], ['C10.314'], ['Z01.542'], ['H02.249.750', 'H02.403.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500.750.280.710.500', 'L01.313.500.750.280.750.500', 'L01.313.500.750.300.188.300.650.500', 'L01.313.500.750.300.710.500', 'L01.313.500.750.300.742.650.500'... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Thoracic epidural block attenuates cardiovascular response to apnea in rabbits. | PURPOSE: Apnea is one of the potential complications during anaesthesia. If sympathetic nerve activity is blocked by epidural anaesthesia, circulatory responses to apnea might change. Our objective was to assess the potential modifying effects of epidural anaesthesia on the cardiovascular responses to apnea in the anim... | ['Anesthesia, Epidural', 'Animals', 'Apnea', 'Blood Pressure', 'Catecholamines', 'Heart Rate', 'Rabbits'] | 9,597,215 | [['E03.155.086.131'], ['B01.050'], ['C08.618.085', 'C23.888.852.130'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.968.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Production and properties of theta-toxin of Clostridium perfringens with special reference to lethal activity. | theta-Toxin of Clostridium perfringens produced in a synthetic medium showed high toxicity. The mouse was killed with 5-10 hemolytic units of the toxin. Neutralization experiments showed that lethal and hemolytic activities were due to the same toxic entity. The amount of theta-toxin expressed in lethal activity reache... | ['Animals', 'Antitoxins', 'Bacterial Toxins', 'Clostridium perfringens', 'Culture Media', 'Guinea Pigs', 'Hemolysin Proteins', 'Lethal Dose 50', 'Mice', 'Neutralization Tests'] | 192,930 | [['B01.050'], ['D12.776.124.486.485.114.573.601', 'D12.776.124.790.651.114.573.601', 'D12.776.377.715.548.114.573.601', 'D20.215.401.601'], ['D23.946.123'], ['B03.300.390.400.200.575', 'B03.353.625.375.500.575', 'B03.510.415.400.200.575'], ['D27.720.470.305', 'E07.206'], ['B01.050.150.900.649.313.992.550'], ['D12.776.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Early transition to oral antibiotic therapy for community-acquired pneumonia: duration of therapy, clinical outcomes, and cost analysis. | Our objective was to compare therapeutic outcome and analyse cost-benefit of a 'conventional' (7-day course of i.v. antibiotic therapy) vs. an abbreviated (2-day i.v. antibiotic course followed by 'switch' to oral antibiotics) therapy for in-patients with community-acquired pneumonia (CAP). We used a multicenter prospe... | ['Administration, Oral', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cefaclor', 'Cefamandole', 'Cephalosporins', 'Community-Acquired Infections', 'Female', 'Health Care Costs', 'Hospitalization', 'Humans', 'Injections, Intravenous', 'Length of Stay', 'Male', 'Middle Aged', 'Pneumonia, Bacterial', 'Prospective ... | 9,893,772 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D02.065.589.099.249.200.155', 'D02.886.665.074.200.155', 'D03.633.100.300.249.200.155'], ['D02.065.589.099.249.150', 'D02.886.665.074.150', 'D03.633.100.300.249.150'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Differences in salivary flow rates in elderly subjects using xerostomatic medications. | Stimulated whole salivary flow rate (SWSFR) was measured in a group of elderly subjects who were examined for the use of xerostomia-inducing medications. SWSFR was significantly reduced in elderly subjects using one of these medications when compared with control subjects (0.94 vs 1.52 ml/min). Increasing use of up to ... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'DMF Index', 'Diuretics', 'Drug Combinations', 'Female', 'Humans', 'Hydrogen-Ion Concentration', 'Male', 'Psychotropic Drugs', 'Saliva', 'Secretory Rate', 'Xerostomia'] | 1,891,244 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.308.980.438.300.350', 'E06.208.266', 'N05.715.360.300.800.438.300.340', 'N06.850.520.308.980.438.300.350', 'N06.890.160.100'], ['D27.505.696.560.500'], ['D26.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Suppression of amber codons in vivo as evidence that mutants derived from Escherichia coli initiator tRNA can act at the step of elongation in protein synthesis. | The absence of a Watson-Crick base pair at the end of the amino acid acceptor stem is one of the features which distinguishes prokaryotic initiator tRNAs as a class from all other tRNAs. We show that this structural feature prevents Escherichia coli initiator tRNA from acting as an elongator in protein synthesis in viv... | ['Amino Acyl-tRNA Synthetases', 'Escherichia coli', 'Glutamine', 'Mutation', 'Peptide Chain Elongation, Translational', 'Peptide Chain Initiation, Translational', 'RNA, Transfer, Amino Acid-Specific', 'RNA, Transfer, Met', 'Substrate Specificity', 'Suppression, Genetic', 'Transfer RNA Aminoacylation'] | 2,649,502 | [['D08.811.464.263.200'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.125.068.330', 'D12.125.095.461', 'D12.125.154.424'], ['G05.365.590'], ['G02.111.660.871.640', 'G03.734.871.640'], ['G02.111.660.871.650', 'G03.734.871.650'], ['D13.444.735.757.700'], ['D13.444.735.757.700.525'], ['G02.111.835'], ['G... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Investigation Into the Effects of Nucleotide Content on the Electrical Characteristics of DNA Plasmid Molecular Wires. | In this study, we investigate the effect of nucleotide content on the conductivity of plasmid length DNA molecular wires covalently bound to high aspect-ratio gold electrodes. The DNA wires were all between [Formula: see text] in length (>6000bp), and contained either 39%, 53%, or 64% GC base-pairs. We compared the cur... | ['DNA', 'Electric Conductivity', 'Electronics', 'Nanotechnology', 'Nucleotides', 'Plasmids'] | 27,824,579 | [['D13.444.308'], ['G01.358.500.249.277'], ['H01.671.293'], ['H01.603', 'J01.897.520.600'], ['D09.408.620', 'D13.695'], ['G05.360.600']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
A comparison of Bayesian and maximum likelihood methods to determine the performance of a point of care test for Helicobacter pylori in the office setting. | OBJECTIVE: Evaluations of point of care tests (PCT) are often hampered by a lack of appropriate gold standards. This study aimed to compare the results of a Bayesian statistical analysis and a maximum likelihood method to evaluate the performance of a PCT for Helicobacter pylori in primary care.METHODS: The Helisal Rap... | ['Aged', 'Aged, 80 and over', 'Bayes Theorem', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Helicobacter Infections', 'Helicobacter pylori', 'Hematologic Tests', 'Humans', 'Likelihood Functions', 'Male', 'Middle Aged', 'Point-of-Care Systems', 'Primary Health Care', 'Reference Standards', 'Sensitivity and Specificit... | 12,583,452 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['C01.150.252.400.466'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Narrative representations of caregivers and emotion dysregulation as predictors of maltreated children's rejection by peers. | This study examined whether maltreated children were more likely than nonmaltreated children to develop poor-quality representations of caregivers and whether these representations predicted children's rejection by peers. A narrative task assessing representations of mothers and fathers was administered to 76 maltreate... | ['Caregivers', 'Child', 'Child Abuse', 'Child Behavior Disorders', 'Female', 'Humans', 'Male', 'Mood Disorders', 'Peer Group', 'Rejection, Psychology', 'Verbal Behavior'] | 11,370,909 | [['M01.085', 'M01.526.485.200', 'N02.360.200'], ['M01.060.406'], ['I01.198.240.856.350.250', 'I01.880.735.900.350.250'], ['F03.625.141'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.600'], ['F01.829.316.483'], ['F01.145.813.565'], ['F01.145.209.908']] | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Auditing bone densitometry and fractures in children with chronic disease. | In a retrospective analysis of bone densitometry scans performed in an audit of 576 children with chronic disease, lean-mass-adjusted bone mineral content (BMC) for the total body and the lumbar spine was marginally lower in children with fractures. However, the predictive ability of different bone mineral densities (B... | ['Absorptiometry, Photon', 'Bone Density', 'Child', 'Chronic Disease', 'Female', 'Fractures, Bone', 'Humans', 'Male', 'Retrospective Studies', 'Statistics as Topic'] | 18,285,391 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['G11.427.100'], ['M01.060.406'], ['C23.550.291.500'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
The torYZ (yecK bisZ) operon encodes a third respiratory trimethylamine N-oxide reductase in Escherichia coli. | The bisZ gene of Escherichia coli was previously described as encoding a minor biotin sulfoxide (BSO) reductase in addition to the main cytoplasmic BSO reductase, BisC. In this study, bisZ has been renamed torZ based on the findings that (i) the torZ gene product, TorZ, is able to reduce trimethylamine N-oxide (TMAO) m... | ['Amino Acid Sequence', 'Anaerobiosis', 'Chromosome Mapping', 'Escherichia coli', 'Isoenzymes', 'Kinetics', 'Molecular Sequence Data', 'NADH, NADPH Oxidoreductases', 'Operon', 'Oxidoreductases', 'Oxidoreductases Acting on CH-NH Group Donors', 'Oxidoreductases, N-Demethylating', 'Plasmids', 'Recombinant Proteins', 'Reve... | 11,004,177 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.062', 'G03.078'], ['E05.393.183'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D08.811.348', 'D12.776.800.300'], ['G01.374.661', 'G02.111.490'], ['L01.453.245.667'], ['D08.811.682.608'], ['G05.360.340.024.686', 'G05.360.340.358.207.500'], ['D08.811.68... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Periportal edema and necrosis as diagnostic histological features of early humoral rejection in ABO-incompatible liver transplantation. | Humoral rejection caused by antidonor blood group A/B antibodies is one of the most important obstacles for successful ABO-incompatible liver transplantation. However, no specific morphologic features of liver biopsies to distinguish humoral rejection from other conditions such as ischemia or sepsis have been satisfact... | ['ABO Blood-Group System', 'Adolescent', 'Adult', 'Antibody Formation', 'Child', 'Child, Preschool', 'Female', 'Graft Rejection', 'Humans', 'Infant', 'Liver', 'Liver Transplantation', 'Living Donors', 'Male', 'Middle Aged', 'Necrosis', 'Portal System', 'Retrospective Studies'] | 14,755,773 | [['D23.050.301.290.031', 'D23.050.705.230.031'], ['M01.060.057'], ['M01.060.116'], ['G12.450.050.370.250'], ['M01.060.406'], ['M01.060.406.448'], ['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A03.620'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chromosome translocations and covert leukemic clones are generated during normal fetal development. | Studies on monozygotic twins with concordant leukemia and retrospective scrutiny of neonatal blood spots of patients with leukemia indicate that chromosomal translocations characteristic of pediatric leukemia often arise prenatally, probably as initiating events. The modest concordance rate for leukemia in identical tw... | ['Base Sequence', 'Core Binding Factor Alpha 2 Subunit', 'DNA', 'DNA Primers', 'Embryonic and Fetal Development', 'Fetal Blood', 'Humans', 'In Situ Hybridization, Fluorescence', 'Infant, Newborn', 'Leukemia', 'Molecular Sequence Data', 'Oncogene Proteins, Fusion', 'Polymerase Chain Reaction', 'RNA, Messenger', 'RUNX1 T... | 12,048,236 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.930.155.200.200'], ['D13.444.308'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G07.345.500.325', 'G08.686.784.170'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Is 'stage of change' related to knowledge of health effects and support for tobacco control? | We examine the heterogeneity among current and former smokers categorized by 'stage of change' with respect to their perceptions about tobacco and tobacco control. Current and former smokers (n = 846) from a general population sample of adults in Ontario, Canada, were subdivided according to the stages of change catego... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Health Behavior', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', 'Smoking Cessation', 'Smoking Prevention', 'Social Perception'] | 11,800,224 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.145.488'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.145.488.732'], ['I02.233.332.812', 'N02.421.726.407.840'], ['F02.463.593.752']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[The modification of nitric oxide production by exogenous substrates of Krebs cycle during acute hypoxia]. | Hypoxia causes the disruption of mitochondria electron respiratory chain, production of active oxygen forms and the unoxidative protection. In experiments on Wistar rats the influence of sodium succinate (50 mg/kg) and 6-ketoglutarate (200 mg/kg) on NO2-, NO3-, urea and polyamines contents in blood and liver under acut... | ['Acute Disease', 'Animals', 'Biogenic Polyamines', 'Citric Acid Cycle', 'Erythrocytes', 'Hypoxia', 'Ketoglutaric Acids', 'Liver', 'Male', 'Nitrates', 'Nitric Oxide', 'Nitrites', 'Rats', 'Rats, Wistar', 'Succinic Acid'] | 16,201,146 | [['C23.550.291.125'], ['B01.050'], ['D02.092.211.415'], ['G02.111.165', 'G03.295.342', 'G03.493.170'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['C23.888.852.079'], ['D02.241.081.337.351.502', 'D02.241.755.465'], ['A03.620'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['D01.339.387', 'D01.625.550.... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dietary protein intake and risk of type 2 diabetes: results from the Melbourne Collaborative Cohort Study and a meta-analysis of prospective studies. | BACKGROUND: Reported associations between protein intake from different sources and type 2 diabetes (T2D) have been inconsistent.OBJECTIVE: We prospectively examined the relations of total, animal, and plant protein intakes with incident T2D.DESIGN: We followed 21,523 participants (women: 61.7%) between 1990 and 2007 f... | ['Blood Glucose', 'Blood Pressure', 'Body Mass Index', 'Diabetes Mellitus, Type 2', 'Dietary Proteins', 'Energy Intake', 'Humans', 'Incidence', 'Muscle Proteins', 'Nutrition Assessment', 'Plant Proteins', 'Risk Factors'] | 27,629,053 | [['D09.947.875.359.448.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C18.452.394.750.149', 'C19.246.300'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.650.240.340'], ['B01.050.150.900.649.313.988.400.11... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Establishment of a multi-dose study of chondroitin sulfate iron colloid for evaluation of the reticuloendothelial system function. | The assay system of chondroitin sulfate iron colloid (CSFe) was established to evaluate the reticuloendothelial system (RES) function in individual rabbits. In the multi-dose study of CSFe, CSFe was repeatedly administered to each individual rabbit with increasing doses (0.6, 1.2, 2.4, 6.0 mg/kg) at set intervals. Bloo... | ['Animals', 'Carbon', 'Chondroitin Sulfates', 'Drug Administration Schedule', 'Drug Combinations', 'Evaluation Studies as Topic', 'Kinetics', 'Male', 'Mononuclear Phagocyte System', 'Phagocytosis', 'Povidone', 'Rabbits', 'Reference Standards'] | 1,430,789 | [['B01.050'], ['D01.268.150'], ['D09.698.373.200.300'], ['E02.319.283'], ['D26.310'], ['E05.337', 'N05.715.360.335'], ['G01.374.661', 'G02.111.490'], ['A15.382.670'], ['G04.417.350', 'G09.188.665', 'G12.450.564.809', 'G12.688'], ['D02.455.326.271.884.533.699', 'D03.383.773.812.615', 'D05.750.716.721.838', 'D25.720.716.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Alcohol and GABA: ethanol intake modifies hippocampal nipecotic acid binding in ethanol-preferring and non-preferring rats. | 3H-nipecotic acid (3H-NIP) binding to GABA uptake recognition sites was studied in the hippocampus of 3 groups of male, Long Evans rats: Group 1: ethanol-naive rats (ENR); Group II: ethanol-preferring rats (DR) and non-preferring rats (NDR), which had consumed about 5 g.kg-1.d-1 and 1 g-1.d-1 of alcohol respectively in... | ['Animals', 'Ethanol', 'GABA Antagonists', 'Hippocampus', 'Male', 'Nipecotic Acids', 'Proline', 'Rats', 'Self Administration', 'gamma-Aminobutyric Acid'] | 2,289,742 | [['B01.050'], ['D02.033.375'], ['D27.505.519.625.240.300', 'D27.505.696.577.240.300'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D03.066.566', 'D03.383.621.566'], ['D12.125.072.401.623'], ['B01.050.150.900.649.313.992.635.505.700'], ['E02.319.890', 'E02.900.890'], ['D02.241.081.114.500.350', 'D12.12... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lessons learned from malaria: Italy's past and sub-Sahara's future. | No longer a major public health concern in developed countries, malaria kills 1-3 million people annually, mostly children under the age of five in sub-Saharan Africa. In 1998, the WHO launched the Roll Back Malaria (RBM) drive to halve malaria mortality by 2010. This article contrasts the problems confronting RBM with... | ['Africa South of the Sahara', 'Child, Preschool', 'Humans', 'Italy', 'Malaria', 'Public Health', 'World Health Organization'] | 15,550,357 | [['Z01.058.290'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['C01.610.752.530', 'C01.920.875'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['N03.540.514.718.800']] | ['Geographicals [Z]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Differential diagnosis of idiopathic normal pressure hydrocephalus from other dementias using diffusion tensor imaging. | BACKGROUND AND PURPOSE: Because DTI can provide good markers of white matter pathology, it could be useful in differentiating white matter changes of INPH from those of other dementias. The aim of this study was, by using DTI, to compare the characteristic white matter changes in INPH with those in AD, subcortical vasc... | ['Aged', 'Aged, 80 and over', 'Dementia', 'Diagnosis, Differential', 'Diffusion Tensor Imaging', 'Female', 'Humans', 'Hydrocephalus, Normal Pressure', 'Male', 'Middle Aged', 'Prospective Studies'] | 21,700,790 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380', 'F03.615.400'], ['E01.171'], ['E01.370.350.578.750', 'E01.370.350.825.500.150.500', 'E01.370.376.537.500', 'E05.629.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.602.750'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.71... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction. | Recent studies indicate that the LKB1 tumour suppressor protein kinase is the major "upstream" activator of the energy sensor AMP-activated protein kinase (AMPK). We have used mice in which LKB1 is expressed at only approximately 10% of the normal levels in muscle and most other tissues, or that lack LKB1 entirely in s... | ['AMP-Activated Protein Kinases', 'Aminoimidazole Carboxamide', 'Animals', 'Glucose', 'Integrases', 'Mice', 'Mice, Knockout', 'Multienzyme Complexes', 'Muscle Contraction', 'Muscle, Skeletal', 'Phenformin', 'Phenotype', 'Protein-Serine-Threonine Kinases', 'Ribonucleotides'] | 15,889,149 | [['D08.811.913.696.620.682.700.085', 'D12.644.360.062', 'D12.776.476.062'], ['D03.383.129.308.030'], ['B01.050'], ['D09.947.875.359.448'], ['D08.811.739.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.649.313.992.635.505... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells. | To identify new therapeutic targets in acute myeloid leukemia (AML), we performed small-molecule and small-interfering RNA (siRNA) screens of primary AML patient samples. In 23% of samples, we found sensitivity to inhibition of colony-stimulating factor 1 (CSF1) receptor (CSF1R), a receptor tyrosine kinase responsible ... | ['Anisoles', 'Antineoplastic Agents', 'Cell Differentiation', 'Cell Survival', 'Culture Media, Conditioned', 'Female', 'Humans', 'Leukemia, Myeloid, Acute', 'Male', 'Paracrine Communication', 'Prognosis', 'Pyrimidines', 'Receptors, Granulocyte-Macrophage Colony-Stimulating Factor', 'Survival Rate', 'Tumor Cells, Cultur... | 30,425,048 | [['D02.355.601.200', 'D02.355.726.158', 'D02.455.426.559.389.657.654.158'], ['D27.505.954.248'], ['G04.152'], ['G04.346'], ['D27.720.470.305.250', 'E07.206.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.275'], ['G04.085.600'], ['E01.789'], ['D03.383.742'], ['D12.776.543.750.705.852.150.310', ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Colwellia marinimaniae sp. nov., a hyperpiezophilic species isolated from an amphipod within the Challenger Deep, Mariana Trench. | An obligately piezophilic strain was isolated from an amphipod crustacean obtained in the Challenger Deep region of the Mariana Trench during the DEEPSEA CHALLENGE expedition. The strain, MTCD1T, grew at extremely high hydrostatic pressures, with a growth range of 80-140 MPa (optimum, 120 MPa) at 6 °C. Phylogenetic ana... | ['Alteromonadaceae', 'Amphipoda', 'Animals', 'Bacterial Typing Techniques', 'Base Composition', 'DNA, Bacterial', 'DNA, Ribosomal', 'Fatty Acids', 'Hydrostatic Pressure', 'Nucleic Acid Hybridization', 'Pacific Ocean', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA', 'Ubiquinone'] | 27,902,293 | [['B03.660.250.021'], ['B01.050.500.131.365.055'], ['B01.050'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['G02.111.080'], ['D13.444.308.212'], ['D13.444.308.475'], ['D10.251'], ['G01.374.715.352'], ['E05.393.661', 'G02.111.611'], ['Z01.756.700'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Unintegrated HIV-1 DNAs are loaded with core and linker histones and transcriptionally silenced. | Upon delivery into the nucleus of the host cell, linear double-stranded retroviral DNAs are either integrated into the host genome to form the provirus or act as a target of the DNA damage response and become circularized. Little is known about the chromatinization status of the unintegrated retroviral DNAs of the huma... | ['DNA Methylation', 'DNA, Viral', 'Gene Silencing', 'HIV-1', 'HeLa Cells', 'Histones', 'Humans', 'Transcription, Genetic'] | 31,685,613 | [['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['D13.444.308.568'], ['G05.308.203.374'], ['B04.820.650.589.650.350.400'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence of Metabolically Healthy Obesity (MHO) and its relation with incidence of metabolic syndrome, hypertension and type 2 Diabetes amongst individuals aged over 20 years in Ahvaz: A 5 Year cohort Study (2009-2014). | BACKGROUND: Today, obesity epidemic is one of the major health problems of the present century. One of the phenotypes of obesity is metabolically healthy obesity. It seems that these obese individuals suffer less from cardiovascular disease and metabolically unhealthy obesity. This study aimed to investigate the preval... | ['Adult', 'Aged', 'Cohort Studies', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Hypertension', 'Incidence', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Obesity', 'Prevalence'] | 28,781,161 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The molar ratios of alpha and beta subunits of the Na+-K+-ATPase differ in distinct subcellular membranes from rat skeletal muscle. | The Na+-K+-ATPase consists of alpha and beta subunits proposed to function as an alpha-beta heterodimer. Skeletal muscle is characterized by expression of alpha1, alpha2, beta1, and beta2 subunit isoforms. The relative molar proportions of each subunit or each protein isoform are not known, yet their subcellular distri... | ['Animals', 'Cell Fractionation', 'Intracellular Membranes', 'Muscle, Skeletal', 'Rats', 'Sodium-Potassium-Exchanging ATPase'] | 9,201,913 | [['B01.050'], ['E05.242.251'], ['A11.284.149.450', 'A11.284.835.514'], ['A02.633.567', 'A10.690.552.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['D08.811.277.040.025.314.750', 'D12.776.157.530.450.162.780', 'D12.776.157.530.450.250.880', 'D12.776.157.530.813.750', 'D12.776.543.585.450.162.800', 'D12.776.543.585... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ectodermal dysplasia in females and inversion of chromosome 9. | Absence of sweat glands, hypotrichosis, hypodontia, characteristic facial features, and intolerance to heat, without dystrophia of the nails, are manifestations of sex linked hypohydrotic ectodermal dysplasia. Three males and two females were affected in a family in which the affected females were also carrying a peric... | ['Adolescent', 'Adult', 'Chromosome Aberrations', 'Chromosome Disorders', 'Chromosome Inversion', 'Chromosomes, Human, 6-12 and X', 'Ectodermal Dysplasia', 'Female', 'Humans', 'Karyotyping', 'Male', 'Pedigree', 'X Chromosome'] | 7,241,545 | [['M01.060.057'], ['M01.060.116'], ['C23.550.210', 'G05.365.590.175'], ['C16.131.260', 'C16.320.180'], ['C23.550.210.190', 'G05.365.590.175.190', 'G05.365.590.770.500', 'G05.558.805.500'], ['A11.284.187.520.300.325', 'G05.360.162.520.300.325'], ['C16.131.077.350', 'C16.131.831.350', 'C16.320.850.250', 'C17.800.804.350'... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Patterns of use of chest physiotherapy in a teaching hospital. | Studies of chest physiotherapy in medical patients have consistently shown benefit only in patients who produce large amounts of sputum. Among surgical patients systematically repeated maximal inspiration is the only procedure that clearly reduces the incidence of post-operative pulmonary complications. Rationalization... | ['Drainage, Postural', 'Female', 'Hospitals, Teaching', 'Humans', 'Male', 'Middle Aged', 'New South Wales', 'Percussion', 'Physical Therapy Modalities', 'Referral and Consultation', 'Respiratory Tract Diseases', 'Sputum', 'Utilization Review'] | 1,804,076 | [['E02.309.221', 'E02.779.358', 'E02.831.535.358', 'E02.880.150'], ['N02.278.020.300', 'N02.278.421.639'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.639.100.750', 'Z01.678.100.373.750'], ['E01.370.600.610'], ['E02.779', 'E02.831.535'], ['N04.452.758.849'], ['C08'], ['A12.200.808'], ['N... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A simple solution for improving reliability of cardiac arrest equipment provision in hospital. | INTRODUCTION: Effective and safe cardiac arrest care in the hospital setting is reliant on the immediate availability of emergency equipment. The patient safety literature highlights deficiencies in current approaches to resuscitation equipment provision, highlighting the need for innovative solutions to this problem.M... | ['Cardiopulmonary Resuscitation', 'Confidence Intervals', 'Emergencies', 'Emergency Service, Hospital', 'Equipment and Supplies, Hospital', 'Female', 'Heart Arrest', 'Hospital Rapid Response Team', 'Humans', 'Male', 'Medicine Chests', 'Patient Care Team', 'Patient Safety', 'Quality Improvement', 'Reproducibility of Res... | 25,151,949 | [['E02.365.647.110'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E07.325'], ['C14.280.383'], ['N04.590.715.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Coapplication of Chicken Litter Biochar and Urea Only to Improve Nutrients Use Efficiency and Yield of Oryza sativa L. Cultivation on a Tropical Acid Soil. | The excessive use of nitrogen (N) fertilizers in sustaining high rice yields due to N dynamics in tropical acid soils not only is economically unsustainable but also causes environmental pollution. The objective of this study was to coapply biochar and urea to improve soil chemical properties and productivity of rice. ... | ['Acids', 'Animals', 'Charcoal', 'Chickens', 'Crops, Agricultural', 'Fertilizers', 'Manure', 'Nitrogen', 'Oryza', 'Phosphorus', 'Soil', 'Tropical Climate', 'Urea'] | 26,273,698 | [['D01.029'], ['B01.050'], ['D01.268.150.150'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['D27.720.031.400'], ['D20.601'], ['D01.268.604', 'D01.362.625'], ['B01.650.940.800.575.912.250.822.616'], ['D01.268.666'], ['D20.721', 'G01.311.820', 'G16.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Repairing holes in the head: a history of cranioplasty. | Cranioplasty is almost as ancient as trephination, yet its fascinating history has been neglected. There is strong evidence that Incan surgeons were performing cranioplasty using precious metals and gourds. Interestingly, early surgical authors, such as Hippocrates and Galen, do not discuss cranioplasty and it was not ... | ['Animals', 'Bone Plates', 'Bone Substitutes', 'Bone Transplantation', 'Craniotomy', 'Dogs', 'Female', 'History, 15th Century', 'History, 16th Century', 'History, 17th Century', 'History, 18th Century', 'History, 19th Century', 'History, 20th Century', 'History, Ancient', 'History, Medieval', 'Humans', 'Male', 'Trephin... | 9,055,300 | [['B01.050'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['D25.130.325', 'J01.637.051.130.325'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['E04.525.190'], ['B01.050.150.900.649.313.750.250.216.200'], ['K01.400.475.500'], ['K01.400.475.750'], ['K01.400.504.750'], ['K01.4... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Humanities [K]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Isolation and characterization of the 10-kDa and 22-kDa polypeptides of higher plant photosystem 2. | Two polypeptides of 10 kDa and 22 kDa, shown to be components of the higher plant photosystem 2, were purified and examined. A NaCl/Triton X-100 treatment was designed, which released these two polypeptides from the thylakoid membrane, in concert with the extrinsic 16-kDa and 23-kDa proteins, concomitant with a loss in... | ['Amino Acids', 'Calcium Chloride', 'Chlorophyll', 'Cholic Acid', 'Cholic Acids', 'Cross Reactions', 'Light-Harvesting Protein Complexes', 'Molecular Weight', 'Peptides', 'Photosynthetic Reaction Center Complex Proteins', 'Plant Proteins', 'Polyethylene Glycols', 'Sodium Chloride'] | 3,525,160 | [['D12.125'], ['D01.146.300', 'D01.210.450.150.150'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['D04.210.500.105.225.130', 'D04.210.500.221.430.130'], ['D04.210.500.105.225', 'D04.210.500.221.430'], ['G12.122.281'], ['D05.500.562.488.490', 'D08.811.600.710.490', 'D12.776.543.930.500.490', ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
CD9P-1 expression correlates with the metastatic status of lung cancer, and a truncated form of CD9P-1, GS-168AT2, inhibits in vivo tumour growth. | BACKGROUND: Loss of CD9 expression has been correlated with a higher motility and metastatic potential of tumour cells originating from different organs. However, the mechanism underlying this loss is not yet understood.METHODS: We produced a truncated form of partner 1 of CD9 (CD9P-1), GS-168AT2, and developed a new m... | ['Animals', 'Cell Line, Tumor', 'Cell Proliferation', 'Female', 'Gene Expression', 'Humans', 'Lung Neoplasms', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Neoplasm Proteins', 'Xenograft Model Antitumor Assays'] | 21,206,492 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Amatoxin intoxication. | Ingestion of mushrooms followed after 6-12 hours by gastrointestinal symptoms and after 3-4 days by hepatic symptoms is diagnostic for the life-threatening amatoxin intoxication and should be treated as soon as possible. Four case histories are reported and recommendations for treatment are given. | ['Acute Kidney Injury', 'Adult', 'Amanita', 'Amanitins', 'Combined Modality Therapy', 'Female', 'Humans', 'Liver Function Tests', 'Male', 'Middle Aged', 'Mushroom Poisoning'] | 2,237,302 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116'], ['B01.300.179.100.110'], ['D04.345.566.050', 'D12.644.456.050', 'D12.644.641.050', 'D23.946.587.175'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.372.460'], ['M01.060.116.630'], ['C25.723.415.551', 'C25.723.680.551']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Postpartum Family Planning During Sociopolitical Transition: Findings from an Integrated Community-Based Program in Egypt. | CONTEXT: Limited information exists on postpartum family planning and implementation of integrated reproductive and maternal and child health programs in countries experiencing sociopolitical transition.METHODS: A quasi-experimental evaluation of an integrated reproductive and maternal and child health program implemen... | ['Adult', 'Child', 'Child Health Services', 'Contraception', 'Egypt', 'Family Planning Services', 'Female', 'Humans', 'Maternal Health Services', 'Postpartum Period', 'Pregnancy', 'Reproduction'] | 28,825,907 | [['M01.060.116'], ['M01.060.406'], ['N02.421.143.130'], ['E02.875.194'], ['Z01.058.266.317'], ['N02.421.143.401', 'N02.421.800.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.143.620', 'N02.421.800.500'], ['G08.686.702'], ['G08.686.784.769'], ['G08.686.784']] | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Optimization of a two-plasmid system for the identification of promoters recognized by RNA polymerase containing Mycobacterium tuberculosis stress response sigma factor, sigmaF. | The previously established two-plasmid system in Escherichia coli for the identification of Mycobacterium tuberculosis promoters that are recognized by RNA polymerase containing the stress response sigma factor sigmaF was optimized. Expression of the M. tuberculosis sigmaF encoded by sigF gene was under the control of ... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Base Sequence', 'Cloning, Molecular', 'DNA-Directed RNA Polymerases', 'Escherichia coli', 'Mycobacterium tuberculosis', 'Plasmids', 'Promoter Regions, Genetic', 'Sequence Analysis, DNA', 'Sigma Factor'] | 15,881,404 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D08.811.913.696.445.735.270'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['G05.360.600'], ['G02.111.57... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Persistent TTX-resistant Na+ current affects resting potential and response to depolarization in simulated spinal sensory neurons. | Small dorsal root ganglion (DRG) neurons, which include nociceptors, express multiple voltage-gated sodium currents. In addition to a classical fast inactivating tetrodotoxin-sensitive (TTX-S) sodium current, many of these cells express a TTX-resistant (TTX-R) sodium current that activates near -70 mV and is persistent... | ['Action Potentials', 'Animals', 'Computer Simulation', 'Ganglia, Spinal', 'Ion Channel Gating', 'Membrane Potentials', 'Mice', 'Mice, Mutant Strains', 'Models, Neurological', 'Neurons, Afferent', 'Nonlinear Dynamics', 'Patch-Clamp Techniques', 'Sodium', 'Sodium Channels', 'Tetrodotoxin'] | 11,535,682 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['L01.224.160'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['G02.111.820.400', 'G04.835.400', 'G07.265.625'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Comparison of laboratory values obtained by phlebotomy versus saline lock devices. | OBJECTIVES: To assess the utility of a peripheral saline lock device (SLD) as an alternative to a second venipuncture for obtaining selected blood samples.METHODS: This prospective study used a comparative design and was conducted in an urban emergency department (ED). Adult patients with an existing SLD in place who r... | ['Adult', 'Blood Chemical Analysis', 'Blood Specimen Collection', 'Catheterization, Peripheral', 'Catheters, Indwelling', 'Emergency Service, Hospital', 'Equipment Design', 'Female', 'Humans', 'Male', 'Middle Aged', 'Phlebotomy', 'Prospective Studies'] | 17,099,189 | [['M01.060.116'], ['E01.370.225.124.100', 'E05.200.124.100'], ['E01.370.225.998.110', 'E04.665.150', 'E05.200.998.110'], ['E02.148.224', 'E04.100.814.529.937', 'E04.502.382.937', 'E05.157.375'], ['E07.132.500'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E05.320'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Stevens-Johnson syndrome induced by combination of imatinib and allopurinol. | We report a case of Stevens-Johnson syndrome (SJS) caused by imatinib combined with allopurinol. An 82-year-old female patient who had a diagnosis of chronic myeloid leukemia was initially treated with imatinib 200 mg/day and allopurinol 100 mg for 42 days, and had a satisfactory hematological response. The dose of ima... | ['Aged, 80 and over', 'Allopurinol', 'Antineoplastic Combined Chemotherapy Protocols', 'Benzamides', 'Chronic Disease', 'Female', 'Humans', 'Imatinib Mesylate', 'Kidney Failure, Chronic', 'Leukemia, Myeloid', 'Piperazines', 'Pyrimidines', 'Stevens-Johnson Syndrome'] | 19,439,939 | [['M01.060.116.100.080'], ['D03.633.100.759.160'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.277.456', 'D02.241.223.100.100.435', 'D02.455.426.559.389.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Integrative care for children with cancer. Project design for the development of an integrative care programme for use in paediatric oncology. | PURPOSE: Purpose of this paper is to describe the project design for the development of a context-specific and patient-focused integrative care programme for an intensive care unit for paediatric oncology to ease the strain of the treatments for patients and their families. Integrative care interventions based on anthr... | ['Delivery of Health Care', 'Humans', 'Integrative Oncology', 'Models, Organizational', 'Neoplasms', 'Program Development'] | 30,477,848 | [['N04.590.374', 'N05.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.463'], ['E05.599.670', 'N04.452.534'], ['C04'], ['N04.452.760']] | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Kinetic approach to the study of primary production in the ocean. | Theoretical arguments for and experimental verification of the kinetic approach to the study of primary production in the ocean are described. According to some kinetic models the increase in pure primary production in the ocean is proportional not to time, but approximately to the square root of time. Calculation of t... | ['Atmosphere', 'Bicarbonates', 'Carbon Dioxide', 'Kinetics', 'Mathematics', 'Oxygen Consumption', 'Periodicity', 'Photosynthesis', 'Phytoplankton', 'Plankton', 'Seasons', 'Seawater', 'Water Microbiology'] | 121,543 | [['G16.500.275.063', 'N06.230.300.100'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['G01.374.661', 'G02.111.490'], ['H01.548'], ['G03.680'], ['G01.910.645', 'G07.180.562'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Developing a satisfaction survey for families of Ohio's nursing home residents. | PURPOSE: The purpose of this project was to develop a reliable and valid family satisfaction instrument for use in Ohio's nursing homes.DESIGN AND METHODS: Investigators worked with an advisory council to develop the survey. Purposive sampling techniques were largely used to select 12 small, medium, and large for-profi... | ['Aged', 'Aged, 80 and over', 'Attitude to Health', 'Consumer Behavior', 'Factor Analysis, Statistical', 'Family', 'Female', 'Humans', 'Long-Term Care', 'Male', 'Middle Aged', 'Nursing Homes', 'Ohio', 'Patient Advocacy', 'Surveys and Questionnaires'] | 12,937,324 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.150', 'N05.300.150'], ['F01.145.236'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.476', 'N02.421.585.476'], ['M01.060.116.630'], ['N02.278.825.6... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[The gas chromatographic detection of glycols and their ethers in biological objects during forensic chemical research]. | A system consisting of two columns with different separation mechanisms may be used for forensic chemical gas chromatographic analysis of glycols and their ethers: (1) with a polar immobile phase and (2) with a low-polar polymeric sorbent in gas adsorption or gas-liquid adsorption variants. Effects of other volatile so... | ['Cadaver', 'Chromatography, Gas', 'Ethers', 'Forensic Medicine', 'Glycols', 'Humans', 'Solvents'] | 7,892,686 | [['C23.550.260.224'], ['E05.196.181.349'], ['D02.355'], ['H02.403.330', 'I01.198.780.937'], ['D02.033.455'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.844']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Patterns of muscular activity during movement in patients with chronic low-back pain. | Bilateral paraspinal electromyogram (EMG) at levels L1-L2 and L4-L5, and abdominal EMG of a group of 20 low-back pain patients were compared to those of a group of 20 pain-free controls during flexion, extension, lateral bending to right and left, and rotation to right and left. The results showed no significant left-r... | ['Abdominal Muscles', 'Adult', 'Analysis of Variance', 'Back Pain', 'Electromyography', 'Female', 'Humans', 'Lumbosacral Region', 'Male', 'Movement', 'Muscles', 'Posture', 'Sex Factors'] | 2,961,090 | [['A02.633.567.050'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C23.888.592.612.107'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.923.176.519'], ['G07.568', 'G11.427.410'], ['A02.633', 'A10.690'], ['G11.427.695'], ['N05.715.... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cyclic peptides incorporating 4-carboxyphenylalanine and phosphotyrosine are potent inhibitors of pp60(c-)(src). | The protein tyrosine kinase, pp60(c-)(src), is involved in cellular signaling and is activated during mitosis and in various tumors. We have been employing cyclic decapeptides to identify the determinants for substrate binding and phosphorylation to develop inhibitors competitive with protein substrates of Src. A struc... | ['Animals', 'CSK Tyrosine-Protein Kinase', 'Enzyme Inhibitors', 'Peptides, Cyclic', 'Phenylalanine', 'Phosphotyrosine', 'Protein-Tyrosine Kinases', 'Structure-Activity Relationship', 'src-Family Kinases'] | 10,819,990 | [['B01.050'], ['D08.811.913.696.620.682.725.800.158'], ['D27.505.519.389'], ['D04.345.566', 'D12.644.641'], ['D12.125.072.050.685', 'D12.125.142.666'], ['D12.125.072.050.875.750', 'D12.125.740.740'], ['D08.811.913.696.620.682.725'], ['G02.111.830', 'G07.690.773.997'], ['D08.811.913.696.620.682.725.800']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour. | BACKGROUND: There is growing appreciation for the importance of bacteria in shaping brain development and behaviour. Adolescence and early adulthood are crucial developmental periods during which exposure to harmful environmental factors can have a permanent impact on brain function. Such environmental factors include ... | ['Animals', 'Anti-Bacterial Agents', 'Behavior, Animal', 'Body Weight', 'Brain', 'Brain-Derived Neurotrophic Factor', 'Gastrointestinal Microbiome', 'Gastrointestinal Tract', 'Mice', 'Tryptophan'] | 25,866,195 | [['B01.050'], ['D27.505.954.122.085'], ['F01.145.113'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A08.186.211'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['G06.591.375', 'G16.500.275.157.049.100... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Caregiver burden and nonachievement of healthy lifestyle behaviors among family caregivers of cardiovascular disease patients. | PURPOSE: To determine whether caregiver burdens are associated with lifestyle behaviors 1 year following the hospitalization of a family member with cardiovascular disease (CVD).DESIGN: Prospective follow-up study of National Heart Lung and Blood Institute sponsored Family Intervention Trial for Heart Health participan... | ['Adult', 'Cardiovascular Diseases', 'Caregivers', 'Confidence Intervals', 'Cost of Illness', 'Female', 'Follow-Up Studies', 'Hospitalization', 'Humans', 'Life Style', 'Logistic Models', 'Male', 'Middle Aged', 'Odds Ratio', 'Prospective Studies', 'Risk Reduction Behavior', 'Surveys and Questionnaires'] | 23,113,777 | [['M01.060.116'], ['C14'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Eye movement and postural sway in dyslexic children during sitting and standing. | In this study, we investigated the eye movement and postural control performance in dyslexic children while reading text and performing Landolt reading when sitting and standing. Fifteen dyslexic and 15 non-dyslexic children were asked to sit in a chair while the eye movements were recorded, and were then asked to stan... | ['Child', 'Dyslexia', 'Eye Movements', 'Female', 'Fixation, Ocular', 'Humans', 'Male', 'Posture', 'Reading', 'Sitting Position', 'Standing Position'] | 30,176,340 | [['M01.060.406'], ['C10.597.606.150.500.300', 'C10.597.606.150.550.200', 'C23.888.592.604.150.500.300', 'C23.888.592.604.150.550.200', 'F03.625.562.400'], ['G11.427.410.140', 'G14.350'], ['G14.350.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.695'], ['L01.559.423.557'], ['G11.427.695.575'], ['G11.42... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Tough, Ultralight, and Water-Adhesive Graphene/Natural Rubber Latex Hybrid Aerogel with Sandwichlike Cell Wall and Biomimetic Rose-Petal-Like Surface. | Graphene aerogel (GA) as a rising multifunctional material has demonstrated great potential for energy storage and conversion, environmental remediation, and high-performance sensors or actuators. However, the commercial use of GA is obstructed by its fragility and high cost. Herein, by a simple stirring-induced foamin... | ['Adhesives', 'Biomimetics', 'Cell Wall', 'Gels', 'Graphite', 'Latex', 'Molecular Conformation', 'Rubber', 'Surface Properties', 'Water'] | 31,818,093 | [['D27.720.013', 'J01.637.016'], ['H01.158.550.100', 'J01.897.120.100'], ['A11.284.183'], ['D20.280.320', 'D26.255.165.320'], ['D01.268.150.300', 'D01.578.300'], ['D05.750.078.625', 'D20.215.721.124', 'D25.720.099.625', 'D25.720.099.750.500', 'D25.720.327.840.239', 'J01.637.051.720.099.625', 'J01.637.051.720.540'], ['G... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Von Willebrand gene tracking by single-tube automated fluorescent analysis of four short tandem repeat polymorphisms. | Molecular diagnosis of von Willebrand disease (VWD) has been hampered by the large size and complex genomic characteristics of the gene involved. For this reason, indirect methods using intragenic polymorphic markers described along the von Willebrand factor (VWF) gene are valuable tools for gene monitoring and linkage... | ['Alleles', 'Automation', 'DNA', 'DNA Primers', 'Electrophoresis, Capillary', 'Female', 'Genetic Linkage', 'Genetic Techniques', 'Haplotypes', 'Heterozygote', 'Humans', 'Introns', 'Male', 'Microscopy, Fluorescence', 'Models, Genetic', 'Pedigree', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'Promoter Regions, ... | 15,886,817 | [['G05.360.340.024.340.030'], ['J01.897.104'], ['D13.444.308'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['E05.196.401.190', 'E05.301.300.190'], ['G05.348'], ['E05.393'], ['G05.380.360'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.340.024.220.400', 'G05.360.340.024.34... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Leukemia and exposure to 1,3-butadiene, styrene and dimethyldithiocarbamate among workers in the synthetic rubber industry. | This study evaluated relations between exposure to 1,3-butadiene (BD), styrene (STY) and dimethyldithiocarbamate (DMDTC) and mortality from leukemia among synthetic rubber industry workers. Subjects were 13130 men employed for at least 1 year during 1943-1991 at any of six plants that manufactured synthetic rubber. Dea... | ['Butadienes', 'Chemical Industry', 'Dimethyldithiocarbamate', 'Hematologic Diseases', 'Humans', 'Leukemia', 'Occupational Diseases', 'Occupational Exposure', 'Risk Assessment', 'Rubber', 'Styrene', 'United States'] | 11,397,410 | [['D02.455.326.271.665.146.240'], ['J01.576.655.437'], ['D02.241.081.251.869.210', 'D02.886.706.175'], ['C15.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337'], ['C24'], ['N06.850.460.350.600'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.85... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
The posterior Cerebellum is involved in constructing Social Action Sequences: An fMRI Study. | Social neuroscience largely ignored the role of the cerebellum, despite its implications in a broad range of tasks and neurological disorders related to social functioning and inferences on others' mental state such as beliefs. One hypothesis states that during human evolution, the cerebellum's function evolved from a ... | ['Adult', 'Brain Mapping', 'Cerebellum', 'Cognition', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Movement', 'Reading', 'Social Skills', 'Young Adult'] | 31,366,954 | [['M01.060.116'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.132.810.428.200'], ['F02.463.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['G07.568', 'G11.427.410'], ['L01.559.423.557'], ['F01.145.813.828', 'F01.829.401.737'], ['M01.060.116.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Eight years of the Mayo International Health Program: what an international elective adds to resident education. | OBJECTIVE: To examine the educational benefits of international elective rotations during graduate medical education.PARTICIPANTS AND METHODS: We studied Mayo International Health Program (MIHP) participants from April 1, 2001, through July 31, 2008. Data from the 162 resident postrotation reports were reviewed and use... | ['Clinical Competence', 'Economics, Medical', 'International Educational Exchange', 'Internship and Residency', 'United States'] | 20,675,512 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['N03.219.300'], ['I01.615.500.650', 'I02.581'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Clubbed fingers in a patient with inflammatory gingival hyperplasia. | The association of clubbing with miscellaneous diseases and its diagnostic implications are such that its detection should prompt consideration of the underlying etiology. We encountered a 48-year-old woman with clubbed fingers and a cauliflower-like gingival swelling on the hard palate of the upper jaw. There were no ... | ['Antibodies, Antinuclear', 'Biopsy', 'Diagnosis, Differential', 'Female', 'Follow-Up Studies', 'Gingiva', 'Gingival Hyperplasia', 'Gingivitis', 'Humans', 'Middle Aged', 'Osteoarthropathy, Secondary Hypertrophic', 'Tooth Extraction'] | 16,415,555 | [['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.171'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Potential cause of lethality of an allele implicated in social evolution in fire ants. | The gene Gp-9 is believed to have a major effect on colony social organization in fire ants, with the presence of b-like alleles in a colony associated with multiple-queen (polygyne) organization. Queens and workers of polygyne Solenopsis invicta homozygous for the b-like allele designated b suffer reduced viability co... | ['Alleles', 'Animals', 'Ants', 'Carrier Proteins', 'Evolution, Molecular', 'Genes, Lethal', 'Genetic Variation', 'Genetics, Population', 'Genotype', 'Homozygote', 'Insect Proteins', 'Polymerase Chain Reaction', 'Polymorphism, Restriction Fragment Length', 'Selection, Genetic', 'Social Behavior'] | 17,080,300 | [['G05.360.340.024.340.030'], ['B01.050'], ['B01.050.500.131.617.720.500.500.875.205'], ['D12.776.157'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.024.340.350'], ['G05.365'], ['H01.158.273.343.335'], ['G05.380'], ['G05.380.554'], ['D12.776.093.500'], ['E05.393.620.500'], ['G05.365.795.595'], ['G05.783'], ['F01.145.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Aggression and Helping as Responses to Same-Sex and Opposite-Sex Rejection in Men and Women. | Research shows that interpersonal rejection increases aggression and decreases helping toward the rejecter. Based on the assumptions of the evolutionary approach, it was hypothesized that aggression would be higher and helping would be lower after rejection by a same-sex rather than an opposite-sex other. Moreover, it ... | ['Adolescent', 'Adult', 'Aggression', 'Female', 'Helping Behavior', 'Humans', 'Interpersonal Relations', 'Male', 'Rejection, Psychology', 'Sex Characteristics', 'Young Adult'] | 29,759,017 | [['M01.060.057'], ['M01.060.116'], ['F01.145.126.125', 'F01.145.813.045'], ['F01.145.813.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F01.145.813.565'], ['G08.686.815'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cytomolecular discrimination of the Am | The cytomolecular discrimination of the Am- and A-genome chromosomes facilitates the selection of wheat-Triticum monococcum introgression lines. Fluorescence in situ hybridisation (FISH) with the commonly used DNA probes Afa family, 18S rDNA and pSc119.2 showed that the more complex hybridisation pattern obtained in T.... | ['Chromosomes, Plant', 'DNA Probes', 'DNA, Plant', 'Genome, Plant', 'Hybridization, Genetic', 'In Situ Hybridization, Fluorescence', 'Microsatellite Repeats', 'Triticum'] | 27,468,932 | [['A11.284.187.560', 'A18.005', 'G05.360.162.560'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['D13.444.308.435'], ['G05.360.340.365'], ['E05.820.150.390', 'G05.090.390'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350', 'E05.200.750.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
First line therapy for metastatic pancreatic cancer. | Metastatic pancreatic cancer remains a difficult disease to treat; however, there are more new drug combinations on the horizon each week. We will discuss the results of the MPACT trial presented at the 2013 ASCO Annual Meeting (Abstracts #4005, #4058, and #4059) and compare to the 2011 FOLFIRINOX data. | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Albumins', 'Antineoplastic Combined Chemotherapy Protocols', 'Clinical Trials, Phase III as Topic', 'Deoxycytidine', 'Drug Administration Schedule', 'Fatigue', 'Humans', 'Middle Aged', 'Neoplasm Metastasis', 'Neutropenia', 'Paclitaxel', 'Pancreatic Neoplasms', '... | 23,846,923 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.034'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E05.318.372.250.250.220', 'N05.715.360.330.250.250.220', 'N06.850.520.450.250.250.220'], ['D03.383.742.680.245.500', 'D13.570.230.329', 'D13.570.685.245.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Multiple sclerosis and polymorphisms of innate pattern recognition receptors TLR1-10, NOD1-2, DDX58, and IFIH1. | Genetic factors are critical in multiple sclerosis (MS), and it is conceivable that the pattern recognition receptors of the innate immune system are of pathogenic importance. We therefore developed two novel assays capable of analyzing 42 single-nucleotide polymorphisms in the human genes encoding TLR1-10, NOD1-2, DDX... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Animals', 'DEAD Box Protein 58', 'DEAD-box RNA Helicases', 'Encephalomyelitis, Autoimmune, Experimental', 'Female', 'Genome-Wide Association Study', 'Genotype', 'Humans', 'Immunity, Innate', 'Interferon-Induced Helicase, IFIH1', 'Male', 'Mice', 'Middle Aged', 'Multi... | 19,450,885 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050'], ['D08.811.913.696.445.735.720.249.750'], ['D08.811.913.696.445.735.720.249'], ['C10.114.703.300', 'C10.228.140.695.562.250', 'C10.314.350.250', 'C20.111.258.625.300', 'E05.598.500.500.500'], ['E05.318.370.392', 'E05.318.416.24... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Utility of toluidine blue as a diagnostic adjunct in the detection of potentially malignant disorders of the oral cavity--a clinical and histological assessment. | BACKGROUND: The value of chairside adjunctive tests in the detection of oral potentially malignant disorders (OPMDs) remains uncertain.OBJECTIVES: To determine the effectiveness of toluidine blue in detecting leukoplakia and erythroplakia and its accuracy in identifying cases with oral epithelial dysplasia.MATERIALS ... | ['Acetic Acid', 'Alcohol Drinking', 'Biopsy', 'Coloring Agents', 'Cytodiagnosis', 'Epithelium', 'Erythroplasia', 'Female', 'Humans', 'Leukoplakia, Oral', 'Male', 'Mouth Mucosa', 'Mouth Neoplasms', 'Precancerous Conditions', 'Sensitivity and Specificity', 'Smoking', 'Tolonium Chloride'] | 22,524,200 | [['D02.241.081.018.165', 'D10.251.400.045.500'], ['F01.145.317.269'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D27.720.233'], ['E01.370.225.500.384', 'E05.200.500.384', 'E05.242.384'], ['A10.272'], ['C04.834.288'], [... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[The angiogram sign in lung consolidation: what is its diagnostic value?]. | The angiogram sign in chest CT is the demonstration of normally enhanced pulmonary branches within hypoattenuating lung parenchyma consolidation. In a retrospective review of the chest CT exams performed in a 2-year period, we identified the angiogram sign in 10 patients with lung consolidation; the diagnosis was centr... | ['Angiography', 'Humans', 'Lung Diseases', 'Sensitivity and Specificity'] | 9,045,236 | [['E01.370.350.700.060', 'E01.370.370.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Design principles of a microtubule polymerase. | Stu2/XMAP215 microtubule polymerases use multiple tubulin-binding TOG domains and a lattice-binding basic region to processively promote faster elongation. How the domain composition and organization of these proteins dictate polymerase activity, end localization, and processivity is unknown. We show that polymerase ac... | ['Binding Sites', 'Cloning, Molecular', 'Gene Expression', 'Genetic Vectors', 'Kinetics', 'Microtubule-Associated Proteins', 'Microtubules', 'Models, Molecular', 'Protein Binding', 'Protein Conformation, alpha-Helical', 'Protein Conformation, beta-Strand', 'Protein Engineering', 'Protein Folding', 'Protein Interaction ... | 29,897,335 | [['G02.111.570.120'], ['E05.393.220'], ['G05.297'], ['G05.360.337'], ['G01.374.661', 'G02.111.490'], ['D12.776.220.600.450', 'D12.776.631.560'], ['A11.284.430.214.190.750.602'], ['E05.599.595'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.600.020'], ['G02.111.570.820.709.600.750'], ['E05.393.420.601'], ['G01.154.... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Concomitant chemoradiation versus neoadjuvant chemotherapy in locally advanced cervical carcinoma: results from two consecutive phase II studies. | BACKGROUND: Randomized studies comparing induction chemotherapy followed by surgical resection with radiation alone found that the neoadjuvant approach produces better results. So far, this latter modality has not been compared with standard concomitant chemoradiation. The objective of this report was to compare the re... | ['Adenocarcinoma', 'Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma, Adenosquamous', 'Carcinoma, Squamous Cell', 'Cisplatin', 'Combined Modality Therapy', 'Deoxycytidine', 'Disease-Free Survival', 'Female', 'Humans', 'Middle Aged', 'Neoadjuvant Therapy', 'Neoplasm Staging', 'Survival Rate',... | 12,181,244 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.557.435.250', 'C04.557.470.200.150'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E02.186'], ['D03.383.742.680.245.500', 'D13.570.230.329'... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effect of work-based mentoring on patient outcome in musculoskeletal physiotherapy: study protocol for a randomised controlled trial. | BACKGROUND: Despite persistent calls to measure the effectiveness of educational interventions on patient outcomes, few studies have been conducted. Within musculoskeletal physiotherapy, the effects of postgraduate clinical mentoring on physiotherapist performance have been assessed, but the impact of this mentoring on... | ['Clinical Competence', 'Clinical Protocols', 'Cost-Benefit Analysis', 'Health Care Costs', 'Humans', 'Inservice Training', 'Mentors', 'Musculoskeletal Diseases', 'Patient Satisfaction', 'Physical Therapists', 'Physical Therapy Modalities', 'Physical Therapy Specialty', 'Research Design', 'Task Performance and Analysis... | 25,344,736 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E02.183', 'N05.715.360.330.125'], ['N03.219.151.125'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.574'], ['M01.395'], ['C05'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Geographica... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Reduced risk of cancer among low-dose aspirin users: Data from French health care databases. | PURPOSE: The effect of chronic use of low-dose aspirin (LDA) on overall cancer is still unclear owing to many controversial results and methodological limitations of studies. This study aimed to assess the effect of LDA use on overall cancer incidence among the French population.METHODS: We conducted a 10-year historic... | ['Aged', 'Aged, 80 and over', 'Aspirin', 'Breast Neoplasms', 'Databases, Factual', 'Dose-Response Relationship, Drug', 'Female', 'Follow-Up Studies', 'France', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Prospective Studies', 'Prostatic Neoplasms', 'Risk Factors'] | 31,338,901 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D02.455.426.559.389.657.410.595.176'], ['C04.588.180', 'C17.800.090.500'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['Z01.542.286... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Preliminary clinical-radiological assessment of a MR tissue signature model in human stroke. | We evaluated the ability of an MR signature model (SM) of cerebral ischemic injury to stage the evolution of cellular damage in human stroke. In 19 patients with ischemic stroke of presumed embolic or non-embolic cause we carried out diffusion-weighted and T2-weighted MR imaging within 48 h of onset, and obtained appar... | ['Adult', 'Aged', 'Aged, 80 and over', 'Animals', 'Brain Ischemia', 'Cerebral Infarction', 'Cerebrovascular Disorders', 'Diagnosis, Computer-Assisted', 'Diagnosis, Differential', 'Disease Models, Animal', 'Female', 'Humans', 'Intracranial Embolism and Thrombosis', 'Magnetic Resonance Angiography', 'Male', 'Middle Aged'... | 9,588,851 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050'], ['C10.228.140.300.150', 'C14.907.253.092'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['C10.228.140.300', 'C14.90... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Laparoscopic Retroperitoneal Nephroureterectomy is a Safe and Adherent Modality for Obese Patients with Upper Urinary Tract Urothelial Carcinoma. | OBJECTIVE: We evaluated the association of body mass index (BMI) with perioperative outcomes in patients who underwent laparoscopic or open radical nephroureterectomy.MATERIALS AND METHODS: This retrospective single-center study included 113 patients who had been diagnosed with upper urinary tract cancer from January 1... | ['Aged', 'Body Mass Index', 'Female', 'Follow-Up Studies', 'Humans', 'Laparoscopy', 'Male', 'Neoplasm Staging', 'Nephrectomy', 'Obesity', 'Prognosis', 'Retroperitoneal Space', 'Retrospective Studies', 'Urologic Neoplasms'] | 25,921,123 | [['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E01.789.625'], ['E... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chinese villages and their sustainable future: the European Union-China-Research Project "SUCCESS". | China has 800,000 villages-one person out of seven on the globe is living in a Chinese rural settlement. Yet the global discussions about the situation in China is currently characterised by a disproportionate focus on the development of towns and until now circumstances have generally been neglected in the rural areas... | ['China', 'Conservation of Natural Resources', 'Ecosystem', 'Environmental Monitoring', 'European Union', 'Humans', 'International Cooperation', 'Research', 'Rural Population'] | 17,888,563 | [['Z01.252.474.164'], ['J01.256', 'N06.230.080'], ['G16.500.275.157', 'N06.230.124'], ['N06.850.460.350.080', 'N06.850.780.375'], ['I01.615.500.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615.500'], ['H01.770.644'], ['N01.600.725']] | ['Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
The Effect of Impact Location on Force Transmission to the Modular Junctions of Dual-Taper Modular Hip Implants. | BACKGROUND: The purpose of this study was to investigate the effect that off-axis impaction has on stability of dual-taper modular implants as measured by forces delivered to and transmitted through the head-neck and neck-stem tapers, respectively.METHODS: One hundred forty-four impact tests were performed using 6 diff... | ['Arthroplasty, Replacement, Hip', 'Computer Simulation', 'Hip Prosthesis', 'Humans', 'Models, Theoretical', 'Prosthesis Design', 'Stress, Mechanical'] | 26,970,905 | [['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['L01.224.160'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['E05.320.550', 'E07.695.680'], ['G01.374.835']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Post-splenectomy infections and Pneumococcus vaccination in paediatric surgery (author's transl)]. | Morbidity and lethality rates in pneumococal infections are higher among children with underlying diseases associated with restricted or absent splenic function. Vaccination with polyvalent vaccine is indicated in all children who are more than 2 years old and who have been splenectomized or have a congenital asplenia.... | ['Antibodies, Bacterial', 'Bacterial Vaccines', 'Child, Preschool', 'Humans', 'Infant', 'Penicillins', 'Pneumococcal Infections', 'Polysaccharides, Bacterial', 'Splenectomy'] | 7,102,107 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D20.215.894.135'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D02.065.589.099.750', 'D02.886.108.750', 'D03.633.100.300.750'], ['C01.150.252.410.890.670'], ['D09.698.718', 'D23... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The Preparation of Hyaluronic Acid Nanoparticles from Aspicilia lichens Using Bifido Bacteria for Help in the Treatment of Diabetes in Rats In Vivo. | Many common herbs and spices are claimed to have blood sugar lowering properties that make them useful for people with or at high risk of diabetes. The main of compounds of kiwifruit (Actinidia deliciosa), rhubarb (Rheum ribes), membrane inner of egg shell, wool of sheep, human fingernail (unguis), hyaluronic acid prod... | ['Animals', 'Ascomycota', 'Benzofurans', 'Bifidobacterium', 'Biological Products', 'Blood Glucose', 'Diabetes Mellitus, Experimental', 'Fruit', 'Humans', 'Hyaluronic Acid', 'Nanoparticles', 'Rats', 'Sheep', 'Spectroscopy, Fourier Transform Infrared'] | 28,782,194 | [['B01.050'], ['B01.300.107'], ['D03.633.100.127'], ['B03.510.024.100', 'B03.510.460.400.400.049.100'], ['D20.215'], ['D09.947.875.359.448.500'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.373.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Necrotizing sialometaplasia involving the nasal cavity. | Necrotizing sialometaplasia is a disease process which affects minor salivary glands. It may clinically and microscopically resemble squamous cell or mucoepidermoid carcinoma but is histologically benign. Thirteen patients with this process occurring on the hard palate have been reported in the past two years. We descr... | ['Aged', 'Female', 'Humans', 'Metaplasia', 'Middle Aged', 'Nasal Cavity', 'Nose', 'Salivary Gland Diseases'] | 839,936 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.589'], ['M01.060.116.630'], ['A04.531.449'], ['A01.456.505.733', 'A04.531', 'A09.531'], ['C07.465.815']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Apoptosis induced by a chimeric Fas/FLICE receptor: lack of requirement for Fas- or FADD-binding proteins. | Current models for Fas (CD95)-mediated apoptosis suggest that FLICE/caspase-8 is recruited and activated, which results in cell death. However, the role of additional molecules in Fas signaling and FLICE activation is not clear. A chimeric Fas/FLICE (F/F) receptor, containing the extracellular/transmembrane portion of ... | ['Adaptor Proteins, Signal Transducing', 'Animals', 'Apoptosis', 'COS Cells', 'Carrier Proteins', 'Caspase 8', 'Caspase 9', 'Caspases', 'Cell Line', 'Cysteine Endopeptidases', 'Cytotoxicity, Immunologic', 'Fas Ligand Protein', 'Fas-Associated Death Domain Protein', 'Genes, Dominant', 'Hybridomas', 'Inhibitor of Apoptos... | 9,498,739 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['B01.050'], ['G04.146.954.035'], ['A11.251.210.172.500', 'A11.329.228.220'], ['D12.776.157'], ['D08.811.277.656.262.500.126.550.800', 'D08.811.277.656.300.200.126.550.800', 'D12.644.360.024.285.037', 'D12.644.360.075.405.550.800', 'D12.644.360.075.421.037', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The â-blocker atenolol lowers the longevity-related degree of fatty acid unsaturation, decreases protein oxidative damage, and increases extracellular signal-regulated kinase signaling in the heart of C57BL/6 mice. | The interruption of the â-adrenergic receptor signaling at the level of adenylyl cyclase (AC) by specifically knocking out (KO) the AC5 gene activates the RAF/MEK/ extracellular signal-regulated kinase (ERK) signaling pathway, delays bone and heart aging, and increases mean and maximum longevity in mice. However, the m... | ['Adrenergic beta-1 Receptor Antagonists', 'Animals', 'Atenolol', 'Biomarkers', 'Electron Transport', 'Extracellular Signal-Regulated MAP Kinases', 'Fatty Acids, Unsaturated', 'Glycosylation', 'Longevity', 'MAP Kinase Signaling System', 'Membrane Lipids', 'Mice', 'Mice, Inbred C57BL', 'Mitochondria, Heart', 'Myocardium... | 20,818,929 | [['D27.505.519.625.050.200.200.100', 'D27.505.696.577.050.200.200.100'], ['B01.050'], ['D02.033.100.624.698.070', 'D02.033.755.624.698.070', 'D02.092.063.624.698.070'], ['D23.101'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.169'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The function of agoraphobia in the marital relationship. | A secondary analysis was carried out of data from a previous experiment on the treatment of agoraphobia. This analysis shows that, contrary to some reports in the literature, agoraphobics do have more problems in the relationship with their partner than the average members of the normal population. The analysis also sh... | ['Adult', 'Agoraphobia', 'Arousal', 'Behavior Therapy', 'Combined Modality Therapy', 'Female', 'Humans', 'Hypnosis', 'Male', 'Marriage', 'Personality Inventory', 'Problem Solving', 'Self Concept', 'Social Environment', 'Stress, Psychological'] | 1,546,556 | [['M01.060.116'], ['F03.080.100'], ['F02.830.104', 'G11.561.035'], ['F04.754.137'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.525.217', 'F04.754.424'], ['F01.829.263.315.500.500', 'I01.240.361.500.500', 'I01.880.853.150.423.500.500', 'N01.224.361.500.500', 'N01.824.308.500.500'], ['F04.711... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Production of B cell stimulatory factor-2/interleukin-6 activity by human endothelial cells. | The effect of culture supernatants of endothelial cell (EC) lines on the immunoglobulin-M(IgM) synthesis by human B cell line, SKW6-CL4 cells, was investigated. Supernatants of human EC stimulated IgM synthesis, as high as 6-fold, but supernatants of bovine EC did not. This enhancing activity was completely blocked by ... | ['Animals', 'Antibodies', 'Cell Line', 'Endothelium, Vascular', 'Humans', 'Immunoglobulin M', 'Interleukin-6', 'Interleukins', 'Rabbits'] | 3,260,491 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['A11.251.210'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.574', 'D12.776.124.790.651.114.619.574', 'D12.776.377.715.548.114.619.574'], ['D12.644.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Common variations in 4p locus are related to male completed suicide. | Suicidal behavior is a multifactorial phenomenon, with a significant genetic predisposition. To assess the contribution of genes in the 4p region to suicide risk, we genotyped 36 single nucleotide polymorphisms from a 49Mb region on the chromosome arm 4p11-16 in a total of 288 male suicide victims and 327 healthy male ... | ['Adolescent', 'Adult', 'Chromosomes, Human, Pair 4', 'Female', 'Genetic Markers', 'Genetic Predisposition to Disease', 'Genotype', 'Haplotypes', 'Humans', 'Male', 'Middle Aged', 'Polymorphism, Genetic', 'Suicide', 'Young Adult'] | 19,115,052 | [['M01.060.057'], ['M01.060.116'], ['A11.284.187.520.300.280.285', 'G05.360.162.520.300.280.285'], ['D23.101.387', 'G05.695.450'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G05.365.795'], ['F01.145.126.980.875', 'I01.880... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Genetic variation in hyaluronan metabolism loci is associated with plasma plasminogen activator inhibitor-1 concentration. | Elevated plasma plasminogen activator inhibitor-1 (PAI-1) concentration is associated with cardiovascular disease risk. PAI-1 is the primary inhibitor of fibrinolysis within both the circulation and the arterial wall, playing roles in both atherosclerosis and thrombosis. To define the heritable component, subjects with... | ['Asian Continental Ancestry Group', 'European Continental Ancestry Group', 'Genetic Variation', 'Genotype', 'Humans', 'Hyaluronic Acid', 'Hyaluronoglucosaminidase', 'Oceanic Ancestry Group', 'Plasminogen Activator Inhibitor 1', 'Polymorphism, Single Nucleotide', 'Serine Endopeptidases'] | 20,558,613 | [['M01.686.508.200'], ['M01.686.508.400'], ['G05.365'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.373.475'], ['D08.811.277.450.529', 'D08.811.520.241.700.675'], ['M01.686.508.600'], ['D12.644.861.695.500', 'D12.776.124.125.640', 'D12.776.872.695.500', 'D23.119.832.500'], ['G05.365.795.598'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Polynucleotides containing 5-mercapto-substituted pyrimidines: inhibition of viral DNA polymerases and the biological implication. | Partially thiolated polycytidylic acids MPC I-III, containing 1.7%, 3.5% and 8.6% 5-mercaptocytidylate units, respectively) inhibited the DNA polymerase of Friend leukemia virus (FLV) in the endogenic reaction as well as in the presence of poly(A)-(dT)14 or poly[d(a-T)] templates; the inhibitory activities were directl... | ['Animals', 'Carcinoma, Ehrlich Tumor', 'DNA Nucleotidyltransferases', 'Escherichia coli', 'Friend murine leukemia virus', 'Kinetics', 'Liver', 'Liver Regeneration', 'Oncogenic Viruses', 'Poly C', 'Polyribonucleotides', 'RNA, Neoplasm', 'RNA, Ribosomal', 'Rats', 'Species Specificity', 'Structure-Activity Relationship',... | 1,103,689 | [['B01.050'], ['C04.557.470.200.200', 'C04.619.169'], ['D08.811.913.696.445.308'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B04.613.807.375.525.225', 'B04.820.650.375.525.225'], ['G01.374.661', 'G02.111.490'], ['A03.620'], ['G10.261.475', 'G16.762.468'], ['B04.613'], ['D13.695.578.550.560'], ['D13.695.... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multimodal approach to mild biliary pancreatitis based on a risk stratification of choledocholithiasis. | AIM: The management of acute mild biliary pancreatitis is multidisciplinary and still presents controversies in the diagnostic and therapeutic strategies. The aim of this retrospective study is to establish if a risk stratification of choledocholithiasis can optimize the employment of technological resources and medica... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Choledocholithiasis', 'Combined Modality Therapy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pancreatitis', 'Retrospective Studies', 'Risk Assessment', 'Severity of Illness Index', 'Young Adult'] | 23,232,477 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C06.130.120.250.174', 'C06.130.409.267'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C06.689.750'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Human trophectoderm apposition is regulated by interferon ã-induced protein 10 (IP-10) during early implantation. | INTRODUCTION: The first step in human implantation is the attraction of the blastocyst to the endometrium. We aimed to study attraction of the human blastocyst to the endometrium, and how this process is accomplished by chemokines secreted by the endometrium.MATERIALS AND METHODS: Blastocyst trophectoderm cells and oth... | ['Adult', 'Cell Movement', 'Cells, Cultured', 'Chemokine CXCL10', 'Chemotaxis', 'Chorionic Villi', 'Culture Techniques', 'Ectoderm', 'Embryo Implantation', 'Endometrium', 'Female', 'Gene Expression Regulation, Developmental', 'Humans', 'Pregnancy', 'Pregnancy Trimester, First', 'Receptors, CXCR3', 'Stromal Cells', 'Tro... | 23,306,067 | [['M01.060.116'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['D12.644.276.374.200.120.500', 'D12.776.467.374.200.120.500', 'D23.125.300.120.500', 'D23.469.200.120.500', 'D23.529.374.200.120.500'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['A... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Thiol/redox metabolomic profiling implicates GSH dysregulation in early experimental graft versus host disease (GVHD). | Graft-versus-host disease (GVHD) is a common complication of allogeneic bone marrow transplantation (BMT). Upregulation of inflammatory cytokines precedes the clinical presentation of GVHD and predicts its severity. In this report, thiol/redox metabolomics was used to identify metabolic perturbations associated with ea... | ['Amino Acids', 'Animals', 'Antioxidants', 'Female', 'Glutamate-Cysteine Ligase', 'Glutathione', 'Graft vs Host Disease', 'Liver', 'Metabolomics', 'Mice', 'Oxidation-Reduction', 'Sulfhydryl Compounds', 'Transplantation, Homologous', 'Tumor Necrosis Factor-alpha', 'Up-Regulation'] | 24,558,439 | [['D12.125'], ['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D08.811.464.259.850.400'], ['D12.644.456.448'], ['C20.452'], ['A03.620'], ['H01.158.201.586', 'H01.158.273.180.599', 'H01.181.122.638'], ['B01.050.150.900.649.313.992.635.505.500'], ['G02.700', 'G03.295.531'], ['D02.886.489'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification and molecular characterization of a prophenoloxidase involved in Aedes aegypti chorion melanization. | Chorion melanization is a vital biochemical event for the survival of mosquito eggs in the environment. This study describes the identification and molecular characterization of a prophenoloxidase (proPO) involved in chorion melanization in Aedes aegypti by various biochemical and molecular techniques. Results revealed... | ['Aedes', 'Amino Acid Sequence', 'Animals', 'Base Sequence', 'Catechol Oxidase', 'Chorion', 'Chromatography, Liquid', 'DNA Primers', 'DNA, Complementary', 'Electrophoresis, Polyacrylamide Gel', 'Enzyme Precursors', 'Gene Expression Regulation, Enzymologic', 'Mass Spectrometry', 'Melanins', 'Molecular Sequence Data', 'O... | 15,796,752 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.682.690.708.125'], ['A10.615.284.473', 'A16.254.750.473'], ['E05.196.181.400'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Predictive value of hypo-osmotic swelling test to identify viable non-motile sperm. | AIM: To determine the predictive value of the hypo-osmotic swelling (HOS) test to identify viable, non-motile sperm.METHODS: Semen samples from 20 men with severe asthenozoospermia underwent traditional seminal analysis, eosin-nigrosin (EN) staining and the HOS test. A further EN stain was then performed on a HOS pre-t... | ['Adult', 'Aniline Compounds', 'Cell Survival', 'Coloring Agents', 'Eosine Yellowish-(YS)', 'Fluorescent Dyes', 'Humans', 'In Vitro Techniques', 'Male', 'Osmotic Pressure', 'Predictive Value of Tests', 'Semen', 'Sperm Motility', 'Spermatozoa'] | 12,937,803 | [['M01.060.116'], ['D02.092.146'], ['G04.346'], ['D27.720.233'], ['D02.455.426.779.347.325', 'D03.633.300.953.275.325', 'D04.711.347.325'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['G01.374.715.578', 'G02.640.249', 'G02.723.661'], ['E05.318.370.800.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Autonomic and haemodynamic responses to SK & F 101468 (ropinirole), a DA2 agonist, in anaesthetised cats. | The haemodynamic and autonomic nervous system effects of the DA2 agonist, SK & F 101468, have been studied in anaesthetised cats. SK & F 101468 inhibited the tachycardia response to cardiac accelerans nerve stimulation. The inhibition, reversed by L-sulpiride a selective DA2 receptor antagonist, was dose-dependent over... | ['Acetylcholine', 'Anesthesia', 'Animals', 'Autonomic Nervous System', 'Blood Pressure', 'Cats', 'Coronary Circulation', 'Dopamine Agents', 'Electric Stimulation', 'Female', 'Heart Rate', 'Hemodynamics', 'Indoles', 'Isoproterenol', 'Male', 'Sulpiride', 'Vagus Nerve', 'Vascular Resistance'] | 1,969,802 | [['D02.092.211.111'], ['E03.155'], ['B01.050'], ['A08.800.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['G09.330.100.324'], ['D27.505.519.625.150', 'D27.505.696.577.150'], ['E05.723.402'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G09.330.380'], ['D03.633.100.4... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A comparison of temperament in nonhuman apes and human infants. | The adaptive behavior of primates, including humans, is often mediated by temperament. Human behavior likely differs from that of other primates in part due to temperament. In the current study we compared the reaction of bonobos, chimpanzees, orangutans, and 2.5-year-old human infants to novel objects and people - as ... | ['Analysis of Variance', 'Animals', 'Behavior, Animal', 'Child, Preschool', 'Female', 'Hominidae', 'Humans', 'Latency Period, Psychological', 'Male', 'Observation', 'Shyness', 'Species Specificity', 'Temperament'] | 22,010,898 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['F01.145.113'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.747.722.458', 'F02.739.794.793.458'], ['E05.581.249'], ['F01.145.813.617'], ['G16.824'], ['F01.75... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Are we heading in the same direction? European and African doctors' and nurses' views and experiences regarding outcome measurement in palliative care. | OBJECTIVE: To examine and compare doctors' and nurses' views and experiences regarding outcome measurement in palliative care, including patient-reported outcome measures (PROMs).METHODS: A web-based survey developed through expert review and piloting was conducted in Europe and Africa with palliative care professional... | ['Adult', 'Africa', 'Aged', 'Data Collection', 'Decision Making', 'Europe', 'Evidence-Based Practice', 'Female', 'Humans', 'Internet', 'Male', 'Middle Aged', 'Nurses', 'Outcome Assessment, Health Care', 'Palliative Care', 'Physicians'] | 21,697,267 | [['M01.060.116'], ['Z01.058'], ['M01.060.116.100'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['F02.463.785.373'], ['Z01.542'], ['H02.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['M01.060.116.630'], ['M01.526.485.650', 'N02.360.650'], ['H01.770.644.145.43... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Validity of sonographic prediction of fetal weight and weight discordance in twin pregnancies. | OBJECTIVES: The aims of this study were (1) to assess the accuracy of estimated fetal weight (EFW) in twins and (2) to assess the accuracy of sonographic examination to predict birth weight discordance (BWD).METHODS: We retrospectively analyzed collected data on twin pregnancies between 2004 and 2007. All twin pregnanc... | ['Adult', 'Algorithms', 'Birth Weight', 'Female', 'Fetal Weight', 'Humans', 'Infant, Newborn', 'Pregnancy', 'Retrospective Studies', 'Twins', 'Ultrasonography, Prenatal'] | 20,187,000 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['C23.888.144.300', 'E01.370.600.115.100.160.120.300', 'E05.041.124.160.750.300', 'G07.100.100.160.120.300', 'G07.345.249.314.120.300', '... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
A comparison of high-resolution melting analysis with denaturing high-performance liquid chromatography for mutation scanning: cystic fibrosis transmembrane conductance regulator gene as a model. | High-resolution melting analysis (HRMA) was compared with denaturing high-performance liquid chromatography (dHPLC) for mutation scanning of common mutations in the cystic fibrosis transmembrane conductance regulator gene. We amplified (polymerase chain reaction under conditions optimized for melting analysis or dHPLC)... | ['Chromatography, High Pressure Liquid', 'Cystic Fibrosis Transmembrane Conductance Regulator', 'DNA Mutational Analysis', 'Exons', 'Humans', 'Mutation', 'Polymerase Chain Reaction', 'Polymorphism, Single Nucleotide'] | 16,191,501 | [['E05.196.181.400.300'], ['D12.776.157.530.100.304.500', 'D12.776.157.530.400.175.125', 'D12.776.157.530.450.074.500.500.500.500', 'D12.776.543.550.450.175.125', 'D12.776.543.585.100.304.500', 'D12.776.543.585.400.175.125', 'D12.776.543.585.450.074.500.500.500.500'], ['E05.393.760.700.300'], ['G05.360.340.024.340.137.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hypercoagulation and fibrinolysis in oral sub-mucous fibrosis. | In seven out of seven patients suffering from oral submucous fibrosis (OSMF), we detected circulating molecules that are immunologically similar to fibrinogen (MISFI), as suggested by the hemagglutination inhibition studies using the FDP Kit (Wellcome) and by paracoagulation tests such as serial dilution protamine test... | ['Blood Coagulation Disorders', 'Blood Coagulation Tests', 'Cryoglobulins', 'Fibrin Fibrinogen Degradation Products', 'Fibrinogen', 'Fibrinogens, Abnormal', 'Fibrinolysis', 'Humans', 'India', 'Mouth Diseases', 'Mouth Mucosa'] | 6,720,629 | [['C15.378.100'], ['E01.370.225.625.115', 'E05.200.625.115'], ['D12.776.124.486.485.900.225', 'D12.776.124.790.651.900.225', 'D12.776.377.715.548.900.225'], ['D12.776.124.270.300', 'D12.776.811.300.290'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['D12.776.124.050.250.265', 'D12.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Applying the law of iterated logarithm to control type I error in cumulative meta-analysis of binary outcomes. | BACKGROUND: Cumulative meta-analysis typically involves performing an updated meta-analysis every time when new trials are added to a series of similar trials, which by definition involves multiple inspections. Neither the commonly used random effects model nor the conventional group sequential method can control the t... | ['Computer Simulation', 'Data Interpretation, Statistical', 'Decision Support Techniques', 'Endpoint Determination', 'Humans', 'Meta-Analysis as Topic', 'Models, Statistical', 'Treatment Outcome'] | 17,848,494 | [['L01.224.160'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['E05.245', 'L01.313.500.750.190'], ['E05.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.500', 'E05.581.500.501', 'N05.715.360.325.515', 'N06.850.520.445.500'], ['E05.318... | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Effects of experimental lead pollution on the microbial communities associated with Sphagnum fallax (Bryophyta). | Ecotoxicological studies usually focus on single microbial species under controlled conditions. As a result, little is known about the responses of different microbial functional groups or individual species to stresses. In an aim to assess the response of complex microbial communities to pollution in their natural hab... | ['Animals', 'Bacteria', 'Ecosystem', 'Eukaryota', 'Fungi', 'Lead', 'Sphagnopsida'] | 17,345,137 | [['B01.050'], ['B03'], ['G16.500.275.157', 'N06.230.124'], ['B01'], ['B01.300'], ['D01.268.556.435', 'D01.552.544.435'], ['B01.650.940.800.575.137.750']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Inhibition of sonic hedgehog autoprocessing in cultured mammalian cells by sterol deprivation. | Sonic hedgehog (Shh) is a signaling molecule that is important for defining patterning in the developing vertebrate central nervous system. After translation, Shh autoproteolyzes and covalently attaches cholesterol to the newly formed carboxyl terminus, a modification crucial for normal Shh signaling. Presented here is... | ['Animals', 'Body Patterning', 'CHO Cells', 'Cricetinae', 'Embryonic Induction', 'Hedgehog Proteins', 'Mice', 'Protein Precursors', 'Protein Processing, Post-Translational', 'Proteins', 'Sterols', 'Trans-Activators'] | 10,860,995 | [['B01.050'], ['G07.345.500.100'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250'], ['G04.085.300', 'G04.152.300', 'G07.345.500.100.250', 'G07.345.500.325.180.750', 'G08.686.784.170.104.750'], ['D12.644.276.671', 'D12.776.467.671', 'D23.529.671'], ['B01.050.150.900.649.313.992.635.505.50... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pre-operative serum levels of CA 242 and CEA predict outcome in colorectal cancer. | The prognostic value of the preoperative serum levels of CA 242 and CEA in patients with colorectal cancer was investigated. The serum concentrations of CA 242 and CEA were determined from preoperative serum samples of 259 patients with colorectal cancer (39 Dukes' A, 100 Dukes' B, 59 Dukes' C and 61 Dukes' D). Surviva... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antigens, Tumor-Associated, Carbohydrate', 'Biomarkers, Tumor', 'Carcinoembryonic Antigen', 'Colorectal Neoplasms', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Survival Rate', 'Treatment Outcome'] | 8,758,246 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.050.285.050', 'D23.050.550.325', 'D23.101.140.075'], ['D23.101.140'], ['D12.776.395.550.200.210', 'D12.776.543.550.200.210', 'D23.050.285.329', 'D23.050.301.350.210', 'D23.101.140.300'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer. | Specific chromosomal deletions sometimes associated with tumours such as retinoblastoma (chromosome 13q14) and Wilm's tumour (chromosome 11p13) have led to the hypothesis that recessive genes may be involved in tumorigenesis. This hypothesis is supported by demonstration of allele loss specific for these regions using ... | ['Alleles', 'Carcinoma, Small Cell', 'Cell Line', 'Chromosome Aberrations', 'Chromosome Deletion', 'Chromosomes, Human, Pair 3', 'DNA, Neoplasm', 'Heterozygote', 'Humans', 'Karyotyping', 'Lung Neoplasms', 'Nucleic Acid Hybridization', 'Polymorphism, Genetic'] | 2,821,400 | [['G05.360.340.024.340.030'], ['C04.557.470.200.380'], ['A11.251.210'], ['C23.550.210', 'G05.365.590.175'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['A11.284.187.520.300.235.250', 'G05.360.162.520.300.235.250... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Left atrial dyssynchrony time measured by tissue Doppler imaging to predict atrial fibrillation recurrences after pulmonary vein isolation. | OBJECTIVE: In this study we assess the value of left atrial dyssynchrony time measured by tissue Doppler imaging (TDI) to predict recurrences after pulmonary vein isolation (PVI) in patients with paroxysmal and persistent atrial fibrillation (AF).METHODS: One hundred sixty patients (57 ± 7.5 years, 122 males) with symp... | ['Atrial Fibrillation', 'Catheter Ablation', 'Echocardiography, Transesophageal', 'Female', 'Heart Atria', 'Humans', 'Male', 'Middle Aged', 'Postoperative Period', 'Predictive Value of Tests', 'Pulmonary Veins', 'Recurrence', 'Ultrasonography, Doppler'] | 25,252,295 | [['C14.280.067.198', 'C23.550.073.198'], ['E02.808.750.500', 'E04.014.760.500'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['A07.541.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.614.750', 'N02.421.585.753.750'], ['E05.318.370.800.650', 'N05.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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