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A Y2H-seq approach defines the human protein methyltransferase interactome. | To accelerate high-density interactome mapping, we developed a yeast two-hybrid interaction screening approach involving short-read second-generation sequencing (Y2H-seq) with improved sensitivity and a quantitative scoring readout allowing rapid interaction validation. We applied Y2H-seq to investigate enzymes involve... | ['Chromatography, Liquid', 'Escherichia coli', 'Gene Expression Regulation, Enzymologic', 'HEK293 Cells', 'Humans', 'Methyltransferases', 'Protein Interaction Mapping', 'Sensitivity and Specificity', 'Sequence Analysis, DNA', 'Tandem Mass Spectrometry', 'Two-Hybrid System Techniques'] | 23,455,924 | [['E05.196.181.400'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.308.320'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.555.500'], ['E05.601.690'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Bilateral single-port thoracoscopic extended thymectomy for management of thymoma and myasthenia gravis: case report. | BACKGROUND: Video-assisted thoracoscopy is become a widely accepted approach for the resection of anterior mediastinal masses, including thymoma. The current trend is to reduce the number of ports and minimize the length of incisions to further decrease postoperative pain, chest wall paresthesia, and length of hospital... | ['Aged', 'Female', 'Humans', 'Myasthenia Gravis', 'Thoracic Surgery, Video-Assisted', 'Thymectomy', 'Thymoma', 'Thymus Neoplasms'] | 27,876,071 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.614.550.500', 'C04.730.856.490', 'C10.114.656', 'C10.574.781.588', 'C10.668.758.725', 'C20.111.258.500'], ['E01.370.388.250.840.830', 'E01.370.388.250.950.830', 'E04.502.250.840.830', 'E04.502.250.950.830', 'E04.928.752.830'], ['E04.928.77... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on humoral immunity: I. Similarities to Staphylococcus aureus Cowan Strain I (SAC) in the in vitro T-dependent antibody response. | We have determined that suppression of the in vitro T-dependent humoral immune response by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on the type and concentration of serum used in the culture media. Only five out of 23 commercial lots of serum (screened at both 5 and 10%) could support a suppression in th... | ['Animals', 'Antibody Formation', 'B-Lymphocytes', 'Culture Media', 'Female', 'In Vitro Techniques', 'Lymphocyte Activation', 'Mice', 'Polychlorinated Dibenzodioxins', 'Staphylococcus aureus', 'T-Lymphocytes'] | 1,917,438 | [['B01.050'], ['G12.450.050.370.250'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D27.720.470.305', 'E07.206'], ['E05.481'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ['B01.050.150.900.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Two forms of RPO41-dependent RNA polymerase. Regulation of the RNA polymerase by glucose repression may control yeast mitochondrial gene expression. | We have identified two chromatographically separable forms of mitochondrial RNA polymerase from Saccharomyces cerevisiae which utilize different DNA templates. One form is only active in a nonselective assay utilizing a poly[d(A-T)] template. The other form selectively initiates from a mitochondrial promoter consensus ... | ['Chromatography', 'DNA, Mitochondrial', 'DNA-Directed RNA Polymerases', 'Gene Expression Regulation', 'Genes, Fungal', 'Glucose', 'Mitochondria', 'Mutation', 'Poly dA-dT', 'Potassium Chloride', 'Promoter Regions, Genetic', 'Saccharomyces cerevisiae', 'Transcription, Genetic'] | 3,045,116 | [['E05.196.181'], ['D13.444.308.283.225'], ['D08.811.913.696.445.735.270'], ['G05.308'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['D09.947.875.359.448'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G05.365.590'], ['D13.695.578.500.300'], ['D01.210.450.150.750', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
L-type Ca2+ channel and ryanodine receptor cross-talk in frog skeletal muscle. | The dihydropyridine receptors (DHPRs)/L-type Ca2+ channels of skeletal muscle are coupled with ryanodine receptors/Ca2+ release channels (RyRs/CRCs) located in the sarcoplasmic reticulum (SR). The DHPR is the voltage sensor for excitation-contraction (EC) coupling and the charge movement component q gamma has been impl... | ['Animals', 'Calcium Channels, L-Type', 'In Vitro Techniques', 'Muscle, Skeletal', 'Nifedipine', 'Rana esculenta', 'Receptor Cross-Talk', 'Ryanodine Receptor Calcium Release Channel'] | 14,660,705 | [['B01.050'], ['D12.776.157.530.400.150.400', 'D12.776.543.550.450.150.400', 'D12.776.543.585.400.150.400'], ['E05.481'], ['A02.633.567', 'A10.690.552.500'], ['D03.383.725.203.540'], ['B01.050.150.900.090.180.708.240'], ['G04.794'], ['D12.776.157.530.400.150.800', 'D12.776.210.500.800', 'D12.776.543.550.450.150.800', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
PCBs and PAHs in sea-surface microlayer and sub-surface water samples of the Venice Lagoon (Italy). | Polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs) are two classes of micropollutants intensively monitored and regulated due to their toxicity, persistency and wide diffusion. Their concentrations have been investigated in sea-microlayer (SML) and sub-surface water (SSW) samples collected at ... | ['Environmental Monitoring', 'Gas Chromatography-Mass Spectrometry', 'Italy', 'Polychlorinated Biphenyls', 'Polycyclic Aromatic Hydrocarbons', 'Seawater', 'Water Pollutants, Chemical'] | 16,212,984 | [['N06.850.460.350.080', 'N06.850.780.375'], ['E05.196.181.349.500', 'E05.196.566.500'], ['Z01.542.489'], ['D02.309.750', 'D02.455.426.559.389.185.698', 'D02.455.526.439.773'], ['D02.455.426.559.847', 'D04.615'], ['G16.500.275.725.500'], ['D27.888.284.903.655']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Chronic pain persists in adults with sickle cell disease despite regular red cell transfusions. | BACKGROUND: Pain affects over 50% of adults with sickle cell disease (SCD), and this pain is largely managed outside of the hospital. While chronic transfusion therapy is used to decrease the rate of acute pain events in patients with SCD, less is known about its impact on the day-to-day experience of pain. To address ... | ['Adult', 'Anemia, Sickle Cell', 'Chronic Pain', 'Erythrocyte Transfusion', 'Female', 'Humans', 'Male', 'Pain Measurement'] | 31,326,289 | [['M01.060.116'], ['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['C23.888.592.612.274'], ['E02.095.135.140.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.600.550.324']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Danger of infection from communion cups--an underestimated risk?]. | The problem of a risk of infection from the common use of chalices has been discussed controversially in literature. Opinions were mainly based on laboratory experiments and theoretical considerations. The authors examined bacterial counts and species existing under normal conditions after communion. For this purpose, ... | ['Bacteria', 'Beverages', 'Christianity', 'Colony Count, Microbial', 'Communicable Diseases', 'Cooking and Eating Utensils', 'Equipment Contamination', 'Food Microbiology', 'Humans', 'Immunocompromised Host', 'Infection Control', 'Risk Factors', 'Rosales', 'Wine'] | 9,686,446 | [['B03'], ['G07.203.100', 'J02.200'], ['K01.844.188'], ['E01.370.225.875.220', 'E05.200.875.220'], ['C01.221', 'C23.550.291.531'], ['J01.494.300', 'J01.576.423.200.300', 'J01.637.370'], ['N06.850.540'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Use of interpreters with crisis intervention teams, behavioral health units, and medical strike teams: responding appropriately and effectively. | The methods of using an interpreter during crisis intervention, medical, and psychological procedures with a non-English speaking patient are often compromised by lack of proper training for both primary healthcare personnel and potential interpreters, and by misunderstandings about effective procedural guidelines. Tra... | ['Emergencies', 'Humans', 'Patient Care Team', 'Translating'] | 21,138,150 | [['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.715'], ['L01.559.423.796']] | ['Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Obstructing cancers of the right and left colon: critical analysis of perioperative risk factors, morbidity, and mortality. | Significant hospital mortality has been observed in right-sided obstructing colonic cancer patients but remains unexplained. The medical records of 52 patients with obstructing colonic cancer seen between 1980-88 were reviewed to identify prognostic factors influencing mortality when carcinoma involved either the right... | ['Aged', 'Aged, 80 and over', 'Colonic Neoplasms', 'Connecticut', 'Female', 'Humans', 'Intestinal Obstruction', 'Length of Stay', 'Male', 'Middle Aged', 'Morbidity', 'Prognosis', 'Risk Factors'] | 1,935,067 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['Z01.107.567.875.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531'], ['E02.760.400.480', 'N02.421.585.... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Novel enzyme-linked immunosorbent assay for determination of fluvastatin in plasma at picogram level. | For the first time, an enzyme-linked immunosorbent assay (ELISA) has been developed and validated for the determination of fluvastatin (FLV) in plasma samples at picogram level. The assay employed a polyclonal antibody that specifically recognizes FLV with high affinity, and FLV conjugate of bovine serum albumin (FLV-B... | ['Animals', 'Antibodies, Monoclonal', 'Cattle', 'Enzyme-Linked Immunosorbent Assay', 'Fatty Acids, Monounsaturated', 'Fluvastatin', 'Humans', 'Indoles', 'Microchemistry', 'Molecular Structure', 'Reproducibility of Results', 'Serum Albumin, Bovine'] | 19,782,210 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['B01.050.150.900.649.313.500.380.271'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D10.251.355.325'], ['D03.633.100.473.305', 'D10.251... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
The two isomers of HDTIC compounds from Astragali Radix slow down telomere shortening rate via attenuating oxidative stress and increasing DNA repair ability in human fetal lung diploid fibroblast cells. | 4-Hydroxy-5-hydroxymethyl-[1,3]dioxolan-2,6'-spirane-5',6',7',8'-tetrahydro-indolizine-3'-carbaldehyde (HDTIC)-1 and HDTIC-2 are two isomers extracted from Astragalus membranaceus (Fisch) Bunge Var. mongholicus (Bge) Hsiao. Our previous study had demonstrated that they could extend the lifespan of human fetal lung dipl... | ['Astragalus propinquus', 'Cell Line', 'Cellular Senescence', 'DNA Repair', 'Dioxolanes', 'Diploidy', 'Female', 'Fetus', 'Fibroblasts', 'Humans', 'Hydrogen Peroxide', 'Indolizines', 'Lung', 'Oxidative Stress', 'Plant Roots', 'Telomere'] | 19,839,736 | [['B01.650.940.800.575.912.250.401.087.750'], ['A11.251.210'], ['G04.043'], ['G02.111.222', 'G05.219'], ['D03.383.246.238'], ['G05.700.264'], ['A16.378'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], [... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Simplified technique for retrograde cerebral perfusion during repair of distal aortic arch and proximal descending thoracic aorta. | Lesions of distal aortic arch and proximal descending thoracic aorta require a posterolateral thoracotomy approach and total circulatory arrest. Retrograde cerebral perfusion through the superior vena cava is technically difficult in such situations. We describe a simplified technique for delivery of retrograde cerebra... | ['Adult', 'Aorta, Thoracic', 'Aortic Diseases', 'Brain', 'Female', 'Humans', 'Jugular Veins', 'Perfusion', 'Vascular Surgical Procedures'] | 12,173,866 | [['M01.060.116'], ['A07.015.114.056.372'], ['C14.907.109'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.908.498'], ['E05.680'], ['E04.100.814']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Repetitive transcranial magnetic stimulation and threat memory: selective reduction of combat threat memory p300 response after right frontal-lobe stimulation. | Using the event-related potential P3a component as a marker, the authors tested the efficacy of repetitive transcranial magnetic stimulation (rTMS) for reducing hyperarousability to specific threat stimuli in one Vietnam veteran with chronic posttraumatic stress disorder (PTSD), who exhibited an exaggerated P3a respons... | ['Combat Disorders', 'Event-Related Potentials, P300', 'Frontal Lobe', 'Humans', 'Male', 'Memory', 'Middle Aged', 'Photic Stimulation', 'Transcranial Magnetic Stimulation'] | 21,304,137 | [['F03.950.750.249'], ['G07.265.216.500.350', 'G11.561.200.500.350'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['M01.060.116.630'], ['E05.723.729'], ['E02.621.820']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of age on sagittal plane profile of the lumbar spine according to standing, supine, and various sitting positions. | BACKGROUND: The sagittal alignment of the spine changes depending on body posture and degenerative changes. This study aimed to observe changes in sagittal alignment of the lumbar spine with different positions (standing, supine, and various sitting postures) and to verify the effect of aging on lumbar sagittal alignme... | ['Adult', 'Age Factors', 'Aged', 'Biomechanical Phenomena', 'Case-Control Studies', 'Female', 'Humans', 'Lumbar Vertebrae', 'Male', 'Posture', 'Prospective Studies', 'Radiography', 'Spine', 'Young Adult'] | 24,571,953 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['G01.154.090', 'G01.374.089'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['G11.427.695'], ['E05.318.372.500.750.625', 'N05.715.36... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Early childhood outcomes of infants born with gastroschisis. | PURPOSE: To describe neonatal and childhood outcomes of a contemporary cohort of infants with gastroschisis.METHODS: Observational, single center, inception cohort of children born with gastroschisis from January 2005 to December 2008.RESULTS: Of 63 infants, 61 survived to hospital discharge and 39 were seen for follow... | ['Abnormalities, Multiple', 'Canada', 'Cholestasis', 'Comorbidity', 'Digestive System Surgical Procedures', 'Enterocolitis, Necrotizing', 'Female', 'Gastroesophageal Reflux', 'Gastroschisis', 'Hospital Mortality', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Infant, Premature, Diseases', 'Length of Stay', 'Male',... | 23,932,607 | [['C16.131.077'], ['Z01.107.567.176'], ['C06.130.120.135'], ['N05.715.350.225', 'N06.850.490.687'], ['E04.210'], ['C06.405.205.596.700', 'C06.405.469.363.700'], ['C06.405.117.119.500.484'], ['C05.660.417', 'C16.131.621.417', 'C23.300.707.374.500'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975... | ['Diseases [C]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Controlled trial of ligation plus nadolol versus nadolol alone for the prevention of first variceal bleeding. | UNLABELLED: Both nadolol and ligation have proved to be effective in the prophylaxis of first variceal bleeding. This study was conducted to evaluate the effects and safety of combining nadolol with ligation. Cirrhotic patients with high-risk esophageal varices but without a bleeding history were considered for enrolme... | ['Adrenergic beta-Antagonists', 'Aged', 'Combined Modality Therapy', 'Esophageal and Gastric Varices', 'Female', 'Gastrointestinal Hemorrhage', 'Humans', 'Ligation', 'Male', 'Middle Aged', 'Nadolol'] | 20,578,138 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116.100'], ['E02.186'], ['C06.405.117.240', 'C06.552.494.414'], ['C06.405.227', 'C23.550.414.788'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.426'], ['M01.060.116.630'], ['D02.033.100.624.698.601', 'D02.033.755.624.698.601', 'D02.09... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Changes in strains of mutans streptococci induced by treatment with chlorhexidine varnish. | Isolates of mutans streptococci were obtained from the dental plaque of ten subjects before and after the subjects had been free of detectable mutans streptococci for a mean period of 14.6 weeks (range, from two to 36 weeks). The mutans streptococci had been rendered undetectable by chlorhexidine varnish treatment. Exa... | ['Adolescent', 'Adult', 'Bacterial Adhesion', 'Chi-Square Distribution', 'Child', 'Chlorhexidine', 'DNA Fingerprinting', 'DNA Restriction Enzymes', 'DNA, Bacterial', 'Dental Plaque', 'Drug Resistance, Microbial', 'Electrophoresis', 'Female', 'Humans', 'Male', 'Middle Aged', 'Species Specificity', 'Streptococcus mutans'... | 1,655,848 | [['M01.060.057'], ['M01.060.116'], ['G06.099.050'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.060.406'], ['D02.078.370.141.100'], ['E05.318.740.225.500.500', 'E05.393.290', 'I01.198.780.937.375', 'N04.452.910.099.750'], ['D08.811.150.280', 'D08.811.277.352.335.3... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[A study of plasma terminal SC5b-9 complement complex in patients with pregnancy induced hypertension]. | OBJECTIVE: To study the relationship between complement SC5b-9 complex and damage of vascular endothelial in pregnancy induced hypertension (PIH).METHODS: Plasma SC5b-9, Serum circulate immunocomplex (CIC), fibronectin (Fn) levels were determined with ELISA in 47 cases of PIH (study group 1) and 15 cases with potential... | ['Adult', 'Antigen-Antibody Complex', 'Complement Membrane Attack Complex', 'Complement System Proteins', 'Endothelium, Vascular', 'Female', 'Fibronectins', 'Glycoproteins', 'Humans', 'Pre-Eclampsia', 'Pregnancy'] | 11,360,651 | [['M01.060.116'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['D12.776.124.486.274.930'], ['D12.776.124.486.274'], ['A07.015.700.500', 'A10.272.491.355'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['D0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Remote critical care consultation: telehealth projection of clinical specialty expertise. | Remote critical care consultations have been employed between the Naval Hospital in Guam and the Tripler Army Medical Center in Hawaii, a distance of 5300 km. During a 10-week study period there were physician-physician daily consultation rounds for patients in the intensive care unit at the Naval Hospital. Physiologic... | ['Critical Care', 'Delivery of Health Care', 'Female', 'Guam', 'Hawaii', 'Heart Arrest', 'Hospitals, Military', 'Humans', 'Middle Aged', 'Remote Consultation'] | 14,728,748 | [['E02.760.190', 'N02.421.585.190'], ['N04.590.374', 'N05.300'], ['Z01.639.760.680.435'], ['Z01.107.567.875.580.375', 'Z01.639.760.815.482'], ['C14.280.383'], ['N02.278.421.510.180.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['L01.178.847.652.550', 'N04.452.758.849.550', 'N04.590.374.80... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Atherosclerotic plaques induced by marble-burying behavior are stabilized by exercise training in experimental atherosclerosis. | BACKGROUND: We assessed the hypothesis whether behavioral stress may affect the development of atherosclerosis and whether regular exercise training may influence the composition of atherosclerotic plaques in apolipoprotein (apo) E-deficient mice.METHODS: Atherosclerosis was induced in apo E-deficient mice fed a high f... | ['Animals', 'Apolipoproteins E', 'Atherosclerosis', 'Diet, High-Fat', 'Disease Models, Animal', 'Male', 'Mice', 'Mice, 129 Strain', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Physical Conditioning, Animal', 'Plaque, Atherosclerotic', 'Stress, Psychological'] | 20,579,750 | [['B01.050'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['C14.907.137.126.307'], ['G07.203.650.240.267'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.400.025', 'B01.050.150.900.649.313.992.635.505.500.550.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sporadic bilateral adrenal medullary hyperplasia: apparent false positive MIBG scan and expected MRI findings. | Adrenal medullary hyperplasia is a rare cause of clinical symptoms and biochemical findings identical to pheochromocytoma occurring mostly in multiple endocrine neoplasia patients. The scenario of positive MIBG scan, but no focal lesion found on CT and MRI led to diagnostic and management difficulties. Like pheochromoc... | ['3-Iodobenzylguanidine', 'Adrenal Gland Neoplasms', 'Adrenal Medulla', 'Adrenalectomy', 'Adult', 'Diagnosis, Differential', 'False Positive Reactions', 'Follow-Up Studies', 'Humans', 'Hyperplasia', 'Hypertension', 'Magnetic Resonance Imaging', 'Male', 'Multiple Endocrine Neoplasia Type 2a', 'Pheochromocytoma', 'Radion... | 10,996,755 | [['D02.078.370.510', 'D02.455.426.559.389.454.300', 'D02.455.526.581.496.300'], ['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['A06.300.071.265'], ['E04.270.115'], ['M01.060.116'], ['E01.171'], ['E01.354.506'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Unsuccessful foley catheterization had an unexpected explanation. | BACKGROUND: Foley catheterization is a simple procedure routinely performed during many obstetric and gynecologic procedures. Failure to adequately drain the bladder with catheter insertion should prompt further investigation to minimize morbidity to the patient.CASE: After repeated attempts to place a Foley catheter d... | ['Adult', 'Cystoscopy', 'Female', 'Humans', 'Oliguria', 'Tomography, X-Ray Computed', 'Ureter', 'Urethral Diseases', 'Urinary Catheterization', 'Urinary Catheters'] | 25,185,614 | [['M01.060.116'], ['E01.370.388.250.180', 'E01.370.390.175', 'E04.502.250.180', 'E04.950.774.155'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.934.600', 'C13.351.968.934.600', 'C23.888.942.400'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Decision-Tree Analysis for Predicting First-Time Pass/Fail Rates for the NCLEX-RN® in Associate Degree Nursing Students. | BACKGROUND: Little evidence shows the use of decision-tree algorithms in identifying predictors and analyzing their associations with pass rates for the NCLEX-RN(®) in associate degree nursing students. This longitudinal and retrospective cohort study investigated whether a decision-tree algorithm could be used to deve... | ['Adolescent', 'Adult', 'Algorithms', 'Decision Support Techniques', 'Decision Trees', 'Education, Nursing, Associate', 'Educational Measurement', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Retrospective Studies', 'Young Adult'] | 27,459,432 | [['M01.060.057'], ['M01.060.116'], ['G17.035', 'L01.224.050'], ['E05.245', 'L01.313.500.750.190'], ['G17.162.500'], ['I02.358.462.233'], ['I02.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['M01.060.116.630'], ['E05.318... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Reporting of estimated glomerular filtration rate (eGFR) in New Zealand--what are the clinical laboratories doing? | INTRODUCTION: Recent guidelines recommend automatic reporting of estimated glomerular filtration rate (eGFR) using the abbreviated Modification of Diet in Renal Disease (MDRD) equation with every request for plasma creatinine in patients aged >18 years. We evaluated the uptake of this recommendation in New Zealand at 6... | ['Adult', 'Aged, 80 and over', 'Clinical Laboratory Information Systems', 'Creatinine', 'Glomerular Filtration Rate', 'Guidelines as Topic', 'Humans', 'Laboratories', 'New Zealand', 'Surveys and Questionnaires'] | 17,151,711 | [['M01.060.116'], ['M01.060.116.100.080'], ['N04.452.515.080'], ['D03.383.129.308.207'], ['E01.370.390.400.300', 'G08.852.357'], ['N04.761.700.350', 'N05.700.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J03.520', 'N02.278.487'], ['Z01.639.760.747', 'Z01.678.100.747'], ['E05.318.308.980', 'N05.715.360.300.8... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Postoperative respiratory compromise in children with obstructive sleep apnea syndrome: can it be anticipated? | OBJECTIVE: The aim of this research was to describe the postoperative respiratory complications after tonsillectomy and/or adenoidectomy (T and/or A) in children with obstructive sleep apnea syndrome (OSAS), to define which children are at risk for these complications, and to determine whether continuous positive airwa... | ['Adenoidectomy', 'Airway Obstruction', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Positive-Pressure Respiration', 'Postoperative Complications', 'Respiratory Insufficiency', 'Retrospective Studies', 'Risk Factors', 'Sleep Apnea Syndromes', 'Tonsillectomy'] | 8,165,079 | [['E04.580.068'], ['C08.618.846.185'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E02.041.625.790', 'E02.880.820.790'], ['C23.550.767'], ['C08.618.846'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular analysis of the genes for human class II antigens of the major histocompatibility complex. | Different cDNA clones have been isolated that encode each of the three chains of HLA-DR antigens: alpha, intermediate and beta, as well as another beta chain, most likely DC. Whereas the DR alpha and intermediate chains seem encoded by single genes, the DR and DC beta chains are most likely encoded by multiple genes; f... | ['Alleles', 'Amino Acid Sequence', 'Base Sequence', 'Cloning, Molecular', 'DNA', 'Gene Expression Regulation', 'Genes', 'Genes, MHC Class II', 'Humans', 'Macromolecular Substances', 'Major Histocompatibility Complex', 'Polymorphism, Genetic', 'Transformation, Genetic'] | 6,414,998 | [['G05.360.340.024.340.030'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308'], ['G05.308'], ['G05.360.340.024.340'], ['G05.360.340.024.340.610.600', 'G05.360.340.024.380.500.600', 'G12.500.500.600'], ['B01.050.150.900.649.313.988.40... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Perceived occupational stress and related factors in public health nurses. | The purposes of this study were to explore perceived occupational stress and related factors in public health nurses (PHNs). A convenient sampling method was used to recruit the subjects. Seven out of 12 district health centers in Taipei City and all 11 district health centers in Kaohsiung City agreed to participate in... | ['Adult', 'Age Factors', 'Attitude of Health Personnel', 'Burnout, Professional', 'Education, Nursing, Continuing', 'Educational Status', 'Female', 'Humans', 'Inservice Training', 'Job Satisfaction', 'Needs Assessment', "Nurse's Role", 'Nursing Methodology Research', 'Nursing Staff', 'Occupational Health', 'Public Heal... | 12,522,738 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.100.050', 'N05.300.100'], ['C24.580.500', 'F01.145.126.990.367.500', 'F02.830.900.333.500'], ['I02.358.212.450', 'I02.358.462.399'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.574'], ['F02.784.692.425'], ['I02.594', 'N03.349.38... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Quantitative assessment of HER2 amplification in HER2-positive breast cancer: its association with clinical outcomes. | Human epidermal growth factor receptor 2 (HER2) is an effective therapeutic target in breast cancer. However, not all patients benefit from trastuzumab-based therapy. We aimed to investigate whether patients with different levels of HER2 amplification would experience different clinical outcomes with trastuzumab-based ... | ['Adult', 'Aged', 'Antineoplastic Agents', 'Breast Neoplasms', 'Centromere', 'Chromosomes, Human, Pair 17', 'Female', 'Gene Amplification', 'Humans', 'Middle Aged', 'ROC Curve', 'Receptor, ErbB-2', 'Survival Analysis', 'Trastuzumab', 'Treatment Outcome', 'Young Adult'] | 25,762,478 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['A11.284.430.106.279.345.190.160.165', 'G05.360.160.165'], ['A11.284.187.520.300.415.425', 'G05.360.162.520.300.415.425'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The influence of reduced susceptibility to fluoroquinolones in Salmonella enterica serovar Typhi on the clinical response to ofloxacin therapy. | BACKGROUND: Infection with Salmonella enterica serovar Typhi (S. Typhi) with reduced susceptibility to fluoroquinolones has been associated with fluoroquinolone treatment failure. We studied the relationship between ofloxacin treatment response and the ofloxacin minimum inhibitory concentration (MIC) of the infecting i... | ['Drug Resistance, Bacterial', 'Fluoroquinolones', 'Humans', 'Microbial Sensitivity Tests', 'Ofloxacin', 'Salmonella typhi', 'Treatment Failure', 'Typhoid Fever', 'Vietnam'] | 21,713,025 | [['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['D03.633.100.810.835.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D03.633.100.810.835.322.500'], ['B03.440.450.425.800.200.800', 'B03.660.250.150.710.160.750'], ['E01.789.800.760', 'N... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Endogenous auxin determines the pattern of adventitious shoot formation on internodal segments of ipecac. | MAIN CONCLUSION: Endogenous auxin determines the pattern of adventitious shoot formation. Auxin produced in the dominant shoot is transported to the internodal segment and suppresses growth of other shoots. Adventitious shoot formation is required for the propagation of economically important crops and for the regenera... | ['Biological Transport', 'Frozen Sections', 'Indoleacetic Acids', 'Ipecac', 'Plant Growth Regulators', 'Plant Roots', 'Plant Shoots', 'Plants, Genetically Modified'] | 32,140,780 | [['G03.143'], ['E01.370.225.500.620.530.160.260', 'E01.370.225.750.600.530.160.260', 'E05.200.500.620.530.160.260', 'E05.200.750.600.530.160.260'], ['D03.066.288', 'D03.633.100.473.404'], ['D20.215.784.500.450'], ['D27.505.696.377.760'], ['A18.400'], ['A18.024.875'], ['B01.650.520', 'B05.620.600']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adsorption of HCN on reduced graphene oxides: a first-principles study. | The interactions between HCN and reduced graphene oxides (rGO) are investigated using first-principles calculations with M06-2X functional. The results show that the adsorption of HCN on rGO is generally stronger than that on graphene, which is due to the presence of the active defect sites in rGO, such as the hydroxyl... | ['Adsorption', 'Graphite', 'Hydroxyl Radical', 'Models, Chemical', 'Models, Molecular', 'Oxides'] | 24,691,535 | [['G01.030', 'G02.020'], ['D01.268.150.300', 'D01.578.300'], ['D01.045.250.357', 'D01.248.497.158.459.300', 'D01.339.431.249'], ['E05.599.495'], ['E05.599.595'], ['D01.248.497.158.685', 'D01.650.550']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The relationship between perinatal hypoxia and newborn encephalopathy. | Newborn encephalopathy was observed in 30% of 303 selected high-risk preterm and term newborn infants. The newborn encephalopathy was mild or moderate in 65 children and severe in 27. The predictive significance of newborn encephalopathy to motor and cognitive deficits at 1 year was evident from the incidence of defici... | ['Brain Diseases', 'Cognition Disorders', 'Developmental Disabilities', 'Female', 'Fetal Hypoxia', 'Follow-Up Studies', 'Gestational Age', 'Humans', 'Hypoxia', 'Infant, Newborn', 'Infant, Premature, Diseases', 'Infections', 'Motor Activity', 'Pregnancy', 'Respiration Disorders', 'Risk', 'Seizures', 'Socioeconomic Facto... | 2,408,473 | [['C10.228.140'], ['F03.615.250'], ['F03.625.421'], ['C13.703.277.390', 'C16.300.420', 'C23.888.852.079.594'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.079'], ['M0... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The evolution of spite: population structure and bacteriocin-mediated antagonism in two natural populations of xenorhabdus bacteria. | Spite occurs when an individual harms itself in the act of harming other individuals. Such behaviors were once assumed to be of limited evolutionary importance, as the conditions for the evolution of spite were thought to be too restrictive. Recent theoretical work, however, suggests that spatial population structure, ... | ['Bacterial Physiological Phenomena', 'Bacteriocins', 'Biological Evolution', 'False Positive Reactions', 'Genetic Variation', 'Genotype', 'Models, Genetic', 'Models, Statistical', 'Species Specificity', 'Xenorhabdus'] | 20,584,073 | [['G06.099'], ['D12.776.097.151', 'D12.776.543.695.110'], ['G05.045', 'G16.075'], ['E01.354.506'], ['G05.365'], ['G05.380'], ['E05.599.395.397'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['G16.824'], ['B03.440.450.425.890', 'B03.660.250.150.910']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Inhibitory properties of nucleotides with difluoromethylenephosphonic acid as a phosphate mimic versus calf spleen purine nucleoside phosphorylase and effect of these analogues on the viability of human blood lymphocytes. | Several cyclic and acyclic 6-keto purine nucleotides with difluoromethylenephosphonic acid as phosphate mimic are proved to be potent inhibitors of mammalian purine nucleoside phosphorylase (PNP). Antiproliferative activity of these analogues on the growth of human blood lymphocytes was tested by MTT assay. Compared to... | ['Animals', 'Cattle', 'Cell Proliferation', 'Cell Survival', 'Drug Design', 'Enzyme Inhibitors', 'Hashimoto Disease', 'Humans', 'In Vitro Techniques', 'Lymphocytes', 'Purine Nucleotides', 'Purine-Nucleoside Phosphorylase', 'Spleen'] | 18,058,523 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['D27.505.519.389'], ['C19.874.871.102.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A11.118.637.555.567', 'A15.145.229.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Heterogeneous vascular response to vasopressin: radial artery versus forearm blood flow. | BACKGROUND: Arginine vasopressin (AVP) administered intra-arterially to normal volunteers exerts a biphasic effect on forearm blood flow when the effect is extrapolated from plethysmographic measurements.OBJECTIVE: To assess whether the high-dose AVP-induced increase in forearm blood flow could be confirmed when calcul... | ['Adult', 'Arginine Vasopressin', 'Blood Flow Velocity', 'Forearm', 'Hemodynamics', 'Humans', 'Infusions, Intra-Arterial', 'Male', 'Muscle, Skeletal', 'Plethysmography', 'Radial Artery', 'Skin', 'Vasoconstriction'] | 9,050,968 | [['M01.060.116'], ['D06.472.699.631.692.781.100', 'D12.644.400.900.100', 'D12.644.456.925.100', 'D12.644.548.691.692.781.100', 'D12.776.631.650.937.100'], ['E01.370.370.130', 'G09.330.380.630.080'], ['A01.378.800.585'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.510.520'], ['A02.633... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cricket: fast bowler's back and thrower's shoulder. | Preventive measures are important in cricket. Although not associated with as high an incidence of injury as contact sports, sudden bursts of extreme exertion after long periods of inactivity in cricket carry their own morbidity. | ['Athletic Injuries', 'Humans', 'Lumbar Vertebrae', 'Shoulder Dislocation', 'Spondylolisthesis', 'Spondylolysis', 'Sports', 'Sports Medicine'] | 2,602,322 | [['C26.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['C05.550.518.750', 'C26.289.750', 'C26.803.125'], ['C05.116.900.938.500.500'], ['C05.116.900.938.500'], ['I03.450.642.845'], ['H02.403.830']] | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Radicals involved in photoallergen/protein interactions. | Aqueous solutions (pH = 8) of both 3,3'-dimethyl and 4,4'-dimethyl substituted analogues of the photoallergen fentichlor (bis(2-hydroxy-5-chlorophenyl)sulphide) produced stable semiquinone radicals when irradiated with u.v. light (greater than 310 nm). These radicals have been characterised using electron spin resonanc... | ['Anti-Infective Agents, Local', 'Binding Sites', 'Chlorophenols', 'Electron Spin Resonance Spectroscopy', 'Free Radicals', 'Humans', 'Methylation', 'Molecular Structure', 'Oxygen', 'Photochemistry', 'Photosensitivity Disorders', 'Proteins', 'Serum Albumin', 'Ultraviolet Rays'] | 2,550,330 | [['D27.505.954.122.187'], ['G02.111.570.120'], ['D02.455.426.559.389.261.190', 'D02.455.426.559.389.657.190'], ['E05.196.867.519.274'], ['D01.339', 'D02.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['G02.111.570', 'G02.466'], ['D01.268.185.550', 'D01.362... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[Treatment of advanced heart failure in women: heart transplantation and ventricular assist devices]. | Women candidates for heart transplantation are definitely less than men, just 20% of all patients transplanted; even in the INTERMACS registry they represent only 21% of all ventricular assist devices (VAD) implanted. The reasons for this big difference are discussed in this article. Why women are less frequently asses... | ['Female', 'Heart Failure', 'Heart Transplantation', 'Heart-Assist Devices', 'Humans', 'Severity of Illness Index'] | 23,678,533 | [['C14.280.434'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.520.308.980.438.475.364.500']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A new direct Fourier transform infrared analysis of free fatty acids in edible oils using spectral reconstitution. | A new transmission-based Fourier transform infrared (FTIR) spectroscopic method for the direct determination of free fatty acids (FFA) in edible oils has been developed using the developed spectral reconstitution (SR) technique. Conventional neat-oil and SR calibrations were devised by spiking hexanoic acid into FFA-fr... | ['Calibration', 'Fatty Acids, Nonesterified', 'Food Analysis', 'Plant Oils', 'Spectroscopy, Fourier Transform Infrared'] | 21,556,753 | [['E05.978.155'], ['D10.251.310'], ['E05.362', 'J01.576.423.850.100'], ['D10.627.700', 'D20.215.784.750'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The taxonomic implication of frontal tubercles in <i>Polypedilum</i> subgenera diagnoses, with re-description of <i>Polypedilum</i> <i>isigabeceum</i> Sasa & Suzuki (Diptera, Chironomidae). | Polypedilum isigabeceum Sasa et Suzuki, 2000 was described as belonging to subgenus Polypedilum s. str. However, if we accept the conclusion of S?ther et al. (2010), the species might be placed into Kribionympha with P. unagiquartum Sasa, 1985 because of the presence of distinct frontal tubercles in the adult males. Ho... | ['Animal Distribution', 'Animal Structures', 'Animals', 'Body Size', 'Chironomidae', 'Male', 'Organ Size'] | 27,988,711 | [['F01.145.113.069', 'G16.049'], ['A13'], ['B01.050'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['B01.050.500.131.617.720.500.500.750.712.500.750'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Heavy metal deposition and variation in sedimentation rate within a sedimentary basin in Central Gulf of Finland. | In studies dealing with the chemical distribution of elements in marine soft sediments, variations in sedimentation rate within a basin can bias the interpretation of the data. A basin in the central part of the Gulf of Finland was sampled at nine sampling sites along a transect, 1.2 nautical miles long. Gravity cores ... | ['Environmental Monitoring', 'Finland', 'Geologic Sediments', 'Metals, Heavy', 'Reference Values', 'Reproducibility of Results'] | 10,101,854 | [['N06.850.460.350.080', 'N06.850.780.375'], ['Z01.542.816.186'], ['G01.311.330', 'G16.500.320'], ['D01.268.556', 'D01.552.544'], ['E05.978.810'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725']] | ['Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Partial immunochemical identity between (Na+ + K+)-ATPase and a membrane component extractable with chloroform: methanol. | An IgG fraction prepared from an antiserum against a holoenzyme preparation of (Na+ + K+)-ATPase precipitated a single antigen when samples of holoenzyme were subjected to crossed immunoelectrophoresis but precipitated an additional, immunochemically-related antigen when a plasma membrane-enriched fraction was subjecte... | ['Animals', 'Antigens', 'Cell Membrane', 'Chloroform', 'Ducks', 'Immunochemistry', 'Immunoelectrophoresis, Two-Dimensional', 'Methanol', 'Salt Gland', 'Sodium-Potassium-Exchanging ATPase'] | 3,013,445 | [['B01.050'], ['D23.050'], ['A11.284.149'], ['D02.455.526.439.224', 'D02.455.526.913.810'], ['B01.050.150.900.248.050.200', 'B01.050.150.900.248.690.345'], ['H01.158.201.486', 'H01.181.122.605', 'H02.403.044.500'], ['E01.370.225.812.735.645.350.350.350', 'E05.196.401.568.520', 'E05.200.812.735.645.350.350.350', 'E05.30... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of a Kinect Software Tool to Classify Movements during Active Video Gaming. | While it has been established that using full body motion to play active video games results in increased levels of energy expenditure, there is little information on the classification of human movement during active video game play in relationship to fundamental movement skills. The aim of this study was to validate ... | ['Adolescent', 'Child', 'Female', 'Humans', 'Joints', 'Male', 'Motor Activity', 'Movement', 'Reproducibility of Results', 'Software', 'Video Games'] | 27,442,437 | [['M01.060.057'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583'], ['F01.145.632', 'G11.427.410.698'], ['G07.568', 'G11.427.410'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['L01.224.900'], ['I03.450.642.693.930', 'L01.224.900.930']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
The EH-domain-containing protein Pan1 is required for normal organization of the actin cytoskeleton in Saccharomyces cerevisiae. | Normal cell growth and division in the yeast Saccharomyces cerevisiae involve dramatic and frequent changes in the organization of the actin cytoskeleton. Previous studies have suggested that the reorganization of the actin cytoskeleton in accordance with cell cycle progression is controlled, directly or indirectly, by... | ['Actins', 'Amino Acid Sequence', 'Cell Cycle', 'Chitin', 'Cytoskeleton', 'Fungal Proteins', 'Microfilament Proteins', 'Molecular Sequence Data', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Sequence Alignment', 'Sequence Homology, Amino Acid', 'src Homology Domains'] | 8,756,649 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G04.144'], ['D05.750.078.139', 'D09.698.211'], ['A11.284.430.214.190.750'], ['D12.776.354'], ['D05.750.078.730', 'D12.776.220.525'], ['L01.453.245.667'], ['B01.300.107.795.785.800', 'B01.300.930.705.655... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Identification of MiRNA from eggplant (Solanum melongena L.) by small RNA deep sequencing and their response to Verticillium dahliae infection. | MiRNAs are a class of non-coding small RNAs that play important roles in the regulation of gene expression. Although plant miRNAs have been extensively studied in model systems, less is known in other plants with limited genome sequence data, including eggplant (Solanum melongena L.). To identify miRNAs in eggplant and... | ['Ascomycota', 'Gene Expression Regulation, Plant', 'MicroRNAs', 'Plant Diseases', 'RNA, Plant', 'Sequence Analysis, RNA', 'Solanum melongena'] | 24,015,279 | [['B01.300.107'], ['G05.308.375'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['G15.610'], ['D13.444.735.635'], ['E05.393.760.710'], ['B01.650.940.800.575.912.250.908.500.725.666']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Syncope due to Brugada syndrome in a young athlete. | A 30-year-old male athlete with exercise-related syncopal symptoms spontaneously exhibited a type 1 Brugada ECG and was inducible during electrophysiology study. He was diagnosed with symptomatic Brugada syndrome and deemed at high risk of sudden cardiac death. Thus, he received a cardioverter/defibrillator and was adv... | ['Adult', 'Brugada Syndrome', 'Death, Sudden, Cardiac', 'Defibrillators, Implantable', 'Humans', 'Male', 'Sports', 'Syncope'] | 17,138,637 | [['M01.060.116'], ['C14.280.067.322', 'C14.280.123.250', 'C16.320.100'], ['C14.280.383.220', 'C23.550.260.322.250'], ['E07.305.250.159.175', 'E07.305.250.319.175', 'E07.695.202.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I03.450.642.845'], ['C10.597.606.358.800.600', 'C23.888.592.604.359.800.600']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
N-[(omega-amino-1-hydroxyalkyl)phenyl]methanesulfonamide derivatives with class III antiarrhythmic activity. | N-[4-[4-(Ethylheptylamino)-1-hydroxybutyl]phenyl]methanesulfonamid e, (E)-2-butenedioate (2:1) salt (ibutilide fumarate, 2E), has been found to have Class III antiarrhythmic activity. In an in vitro rabbit heart tissue preparation designed to evaluate the cardiac electrophysiology of potential antiarrhythmic agents, it... | ['Animals', 'Anti-Arrhythmia Agents', 'Arrhythmias, Cardiac', 'Dogs', 'Female', 'Heart', 'Heart Ventricles', 'In Vitro Techniques', 'Indicators and Reagents', 'Magnetic Resonance Spectroscopy', 'Male', 'Molecular Structure', 'Myocardial Contraction', 'Myocardial Infarction', 'Rabbits', 'Structure-Activity Relationship'... | 1,992,131 | [['B01.050'], ['D27.505.954.411.097'], ['C14.280.067', 'C23.550.073'], ['B01.050.150.900.649.313.750.250.216.200'], ['A07.541'], ['A07.541.560'], ['E05.481'], ['D27.720.470.410'], ['E05.196.867.519'], ['G02.111.570', 'G02.466'], ['G09.330.580', 'G11.427.494.570'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endotoxin alteration of muscle microvascular renin-angiotensin responses. | Endotoxin decreases arteriolar sensitivity to norepinephrine and sympathetic neural activity, but vasopressin sensitivity is increased. Vascular responses to the renin-angiotensin system may also be altered by endotoxin (ENDT). Reactivity of cremaster muscle microvessels of pentobarbital anesthetized Wistar rats was st... | ['Angiotensin II', 'Animals', 'Arterioles', 'Blood Pressure', 'Endotoxins', 'Male', 'Muscles', 'Rats', 'Rats, Inbred Strains', 'Renin', 'Saralasin', 'Shock, Septic', 'Vasoconstriction', 'Venules'] | 1,611,706 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['A07.015.114.060', 'A07.015.461.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D23.946.123.329'], ['A02.633', 'A10.690'], ['B01.050.150.900.649.313.992.635... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Studies of the allosteric properties of maize leaf phosphoenolpyruvate carboxylase with the phosphoenolpyruvate analog phosphomycin as activator. | The antibiotic phosphomycin (1,2-epoxypropylphosphonic acid), an analog of phosphoenolpyruvate (PEP), behaved not as an inhibitor, but as an activator, of the enzyme phosphoenolpyruvate carboxylase (PEPC) from maize leaves. Multiple activation studies indicated that the analog binds to the Glc6P-allosteric site produci... | ['Allosteric Regulation', 'Drug Interactions', 'Enzyme Activation', 'Fosfomycin', 'Glycerol', 'Kinetics', 'Magnesium', 'Models, Chemical', 'Phosphoenolpyruvate', 'Phosphoenolpyruvate Carboxylase', 'Plant Leaves', 'Zea mays'] | 9,675,261 | [['G02.111.044'], ['G07.690.773.968'], ['G02.111.263', 'G03.328'], ['D02.705.429.625'], ['D02.033.800.875.500', 'D09.853.875.500'], ['G01.374.661', 'G02.111.490'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['E05.599.495'], ['D02.241.511.701'], ['D08.811.520.224.125.650'], ['A18.024.812'], ['B01.650.940... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Novel photodynamic effects of a benzophenothiazine on two different murine sarcomas. | The photochemotherapeutic properties of a novel benzophenothiazine, 5-ethylamino-9-diethylaminobenzo[a]phenothiazinium chloride, were assessed in vitro and in vivo against two murine mammary sarcoma models (EMT-6 and RIF). Photodynamic therapy (PDT) of EMT-6 and RIF cells following a 30-min incubation with dye (0.4 mic... | ['Animals', 'Antineoplastic Agents', 'Cell Survival', 'Chemical Phenomena', 'Chemistry, Physical', 'Disease Models, Animal', 'Fluorescent Dyes', 'Indomethacin', 'Male', 'Mammary Neoplasms, Experimental', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C3H', 'Muscles', 'Photochemotherapy', 'Prostaglandins', 'Sarcoma, Exper... | 8,118,813 | [['B01.050'], ['D27.505.954.248'], ['G04.346'], ['G02'], ['H01.181.529'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D03.633.100.473.420'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.496.843'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
In vitro study to evaluate the cytotoxicity of BPA analogues based on their oxidative and genotoxic potential using human peripheral blood cells. | Although Bisphenol-A (BPA) has been found to exhibit toxicological properties such as genotoxicity and oxidative stress, yet there is very little data available on its analogues. Since the replacement of BPA by its analogues, their presence has been found to increase in the environment leading to increased human exposu... | ['Adult', 'Benzhydryl Compounds', 'Cell Survival', 'Cells, Cultured', 'Comet Assay', 'DNA Damage', 'Glutathione', 'Humans', 'Leukocytes, Mononuclear', 'Mutagens', 'Oxidative Stress', 'Phenols', 'Reactive Oxygen Species'] | 31,173,877 | [['M01.060.116'], ['D02.455.426.559.389.115'], ['G04.346'], ['A11.251'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.940.560.150'], ['G05.200'], ['D12.644.456.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555', 'A15.145.229.637.555', 'A15.382.490.555'], ['D27.888.569.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A mortality study of workers exposed to insoluble forms of beryllium. | This study investigated lung cancer and other diseases related to insoluble beryllium compounds. A cohort of 4950 workers from four US insoluble beryllium manufacturing facilities were followed through 2009. Expected deaths were calculated using local and national rates. On the basis of local rates, all-cause mortality... | ['Berylliosis', 'Beryllium', 'Cause of Death', 'Cohort Studies', 'Employment', 'Female', 'Humans', 'Male', 'Occupational Exposure', 'Respiratory Tract Diseases', 'United States', 'Uterine Neoplasms'] | 24,589,746 | [['C08.381.483.581.225', 'C08.381.520.702.225', 'C24.800.225'], ['D01.268.552.075', 'D01.268.557.080', 'D01.552.547.080'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N0... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Fatal non-transplant-related epstein-barr virus-associated atypical lymphoid proliferations in infants and children: a clinicopathologic study. | Most Epstein-Barr virus (EBV)-related infections in infants and children are asymptomatic or self-limited mild viral illnesses, but rare cases of a rapidly fatal disorder have been described. Failure of the cellular response to control EBV-related lymphoid proliferation leads to severe disease with multiple complicatio... | ['Antigens, CD', 'Child, Preschool', 'Clone Cells', 'Epstein-Barr Virus Infections', 'Fatal Outcome', 'Female', 'Herpesvirus 4, Human', 'Humans', 'Immunoenzyme Techniques', 'Immunophenotyping', 'Infant', 'Liver', 'Lymph Nodes', 'Lymphocytes', 'Lymphoproliferative Disorders', 'Male', 'Necrosis', 'RNA-Binding Proteins', ... | 18,473,605 | [['D23.050.301.264.035', 'D23.101.100.110'], ['M01.060.406.448'], ['A11.251.353'], ['C01.925.256.466.313', 'C01.925.928.313'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In search of the tumour-suppressor functions of BRCA1 and BRCA2. | Hereditary breast and ovarian cancer syndromes can be caused by loss-of-function germline mutations in one of two tumour-suppressor genes, BRCA1 and BRCA2 (ref. 1). Each gene product interacts with recombination/DNA repair proteins in pathways that participate in preserving intact chromosome structure. However, it is u... | ['BRCA1 Protein', 'BRCA2 Protein', 'Chromatin', 'DNA', 'DNA-Directed DNA Polymerase', 'Female', 'Genes, BRCA1', 'Genes, Tumor Suppressor', 'Humans', 'Neoplasm Proteins', 'Neoplasms', 'Ovarian Neoplasms', 'Recombination, Genetic', 'S Phase', 'Transcription Factors', 'Transcription, Genetic'] | 11,100,717 | [['D12.776.313.125', 'D12.776.624.776.100', 'D12.776.660.100', 'D12.776.744.100', 'D12.776.930.137'], ['D12.776.313.249', 'D12.776.624.776.101', 'D12.776.660.105'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D13.444.308'], ['D08.811.913.696.445.308.300'], ['G05.360.340.024.340.375.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of a high-performance liquid chromatography method for the simultaneous quantification of quinoxaline-2-carboxylic acid and methyl-3-quinoxaline-2-carboxylic acid in animal tissues. | A method of high-performance liquid chromatography with UV detection has been established for simultaneous quantitative determination of quinoxaline-2-carboxylic acid (QCA) and methyl-3-quinoxaline-2-carboxylic acid (MQCA), the marker residues for carbadox (CBX) and olaquindox (OLA), respectively, in the muscles and li... | ['Animals', 'Chickens', 'Chromatography, High Pressure Liquid', 'Fishes', 'Liver', 'Muscles', 'Quinoxalines', 'Reproducibility of Results', 'Swine'] | 17,335,836 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.196.181.400.300'], ['B01.050.150.900.493'], ['A03.620'], ['A02.633', 'A10.690'], ['D03.633.100.857'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Analysis of methionine metabolism studied by the gas chromatographic determination of 3-methylthiopropionate in urine and its clinical application]. | Methionine is a sulfur-containing essential amino acid and there are optic isomers of L- and D-type. It has been known that there are two metabolic pathways in methionine metabolism-the transsulfuration and the transamination. The purposes of the present investigation are to clarify the existence of transaminative path... | ['Adult', 'Chromatography, Gas', 'Female', 'Humans', 'Liver Cirrhosis', 'Male', 'Methionine', 'Middle Aged', 'Propionates'] | 3,997,054 | [['M01.060.116'], ['E05.196.181.349'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.355.412'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.166.676'], ['M01.060.116.630'], ['D02.241.081.751', 'D10.251.400.706']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Molecular variation at a candidate gene implicated in the regulation of fire ant social behavior. | The fire ant Solenopsis invicta and its close relatives display an important social polymorphism involving differences in colony queen number. Colonies are headed by either a single reproductive queen (monogyne form) or multiple queens (polygyne form). This variation in social organization is associated with variation ... | ['Alleles', 'Amino Acid Sequence', 'Amino Acid Substitution', 'Animals', 'Ants', 'Behavior, Animal', 'Genetic Variation', 'Genetics, Behavioral', 'Molecular Sequence Data', 'Phylogeny'] | 17,987,107 | [['G05.360.340.024.340.030'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['B01.050.500.131.617.720.500.500.875.205'], ['F01.145.113'], ['G05.365'], ['F04.096.276', 'H01.158.273.343.290'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Memory-delineated subtypes of schizophrenia: relationship to clinical, neuroanatomical, and neurophysiological measures. | Memory performance was examined in patients with schizophrenia to determine whether subgroups conforming to cortical and subcortical dementias could be identified and, if so, whether subgroups differed on clinical, neuroanatomical, and neurophysiological measures. A cluster analysis of California Verbal Learning Test p... | ['Adult', 'Brief Psychiatric Rating Scale', 'Female', 'Fluorodeoxyglucose F18', 'Frontal Lobe', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Memory Disorders', 'Neuropsychological Tests', 'Prefrontal Cortex', 'Radiopharmaceuticals', 'Schizophrenia', 'Temporal Lobe', 'Tomography, Emission-Computed', 'Verbal Learning... | 12,382,987 | [['M01.060.116'], ['F04.711.513.653.083'], ['D09.254.229.500'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C10.597.606.525', 'C23.888.592.604.529', 'F01.700.625'], ['F04.711.513'], ['A08.186.211.200.885.287.500.270.700'], ['D27.505.259.843', 'D27.505... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Brain perfusion in fibromyalgia patients and its differences between responders and poor responders to gabapentin. | INTRODUCTION: The aim of the present study was to determine the brain areas associated with fibromyalgia, and whether pretreatment regional cerebral blood flow (rCBF) can predict response to gabapentin treatment.METHODS: A total of 29 women with fibromyalgia and 10 healthy women (without pain) matched for age were fina... | ['Adult', 'Aged', 'Amines', 'Analgesics', 'Brain', 'Cerebrovascular Circulation', 'Cyclohexanecarboxylic Acids', 'Cysteine', 'Female', 'Fibromyalgia', 'Gabapentin', 'Humans', 'Middle Aged', 'Organotechnetium Compounds', 'Radiopharmaceuticals', 'Tomography, Emission-Computed, Single-Photon', 'Treatment Failure', 'Young ... | 20,374,641 | [['M01.060.116'], ['M01.060.116.100'], ['D02.092'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['A08.186.211'], ['G09.330.100.159'], ['D02.241.223.268', 'D02.455.426.392.368.367.218'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['C05.651.324', 'C05.799.321', 'C10.668.491.425'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Shh influences cell number and the distribution of neuronal subtypes in dorsal root ganglia. | The molecular mechanisms responsible for specifying the dorsal-ventral pattern of neuronal identities in dorsal root ganglia (DRG) are unclear. Here we demonstrate that Sonic hedgehog (Shh) contributes to patterning early DRG cells. In vitro, Shh increases both proliferation and programmed cell death (PCD). Increasing ... | ['Animals', 'Bromodeoxyuridine', 'Cell Culture Techniques', 'Cell Division', 'Chick Embryo', 'Ganglia, Spinal', 'Hedgehog Proteins', 'Immunohistochemistry', 'In Situ Hybridization', 'In Situ Nick-End Labeling', 'Neurons', 'Neurons, Afferent'] | 18,190,905 | [['B01.050'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A13.350.150', 'A16.331.200'], ['A08.340.390.340', 'A08.800.350.340', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Bacterial pathogens in chronic otitis media with effusion in Alaska Native children. | This study examined the bacterial pathogens and the presence of possible risk factors for the development of chronic otitis media with effusion (OME) in a group of Alaska Native children. Middle ear aspirates were collected from 128 children < 6 years of age requiring tympanocentesis between 1987 and 1989. Bacterial pa... | ['Alaska', 'Child, Preschool', 'Chronic Disease', 'Female', 'Haemophilus Infections', 'Haemophilus influenzae', 'Humans', 'Infant', 'Inuits', 'Male', 'Otitis Media with Effusion', 'Pneumococcal Infections', 'Risk Factors'] | 10,434,443 | [['Z01.107.567.875.580.100'], ['M01.060.406.448'], ['C23.550.291.500'], ['C01.150.252.400.700.433'], ['B03.440.450.600.450.330', 'B03.660.250.550.290.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.686.508.150.600.375.500', 'M01.686.508.150.675', 'M01.686.754.254.500.500'], ['C09.218.705.... | ['Geographicals [Z]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Selectivity of the beta-adrenergic receptor among Gs, Gi's, and Go: assay using recombinant alpha subunits in reconstituted phospholipid vesicles. | The selective regulation of Gs (long and short forms), Gi's (1, 2, and 3), and Go by the beta-adrenergic receptor was assessed quantitatively after coreconstitution of purified receptor, purified G-protein beta gamma subunits, and individual recombinant G-protein alpha subunits that were expressed in and purified from ... | ['Animals', 'Brain Chemistry', 'Cattle', 'Dithiothreitol', 'Erythrocytes', 'Escherichia coli', 'GTP Phosphohydrolases', 'GTP-Binding Proteins', "Guanosine 5'-O-(3-Thiotriphosphate)", 'Guanosine Diphosphate', 'Kinetics', 'Liposomes', 'Macromolecular Substances', 'Phospholipids', 'Receptors, Adrenergic, beta', 'Recombina... | 1,657,154 | [['B01.050'], ['G02.111.150', 'G03.185'], ['B01.050.150.900.649.313.500.380.271'], ['D02.033.800.196', 'D02.886.740.224', 'D09.853.196'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D08.811.277.040.330'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Backbone and stereospecific (13)C methyl Ile (ä1), Leu and Val side-chain chemical shift assignments of Crc. | Carbon catabolite repression (CCR) allows bacteria to selectively assimilate a preferred compound among a mixture of several potential carbon sources, thus boosting growth and economizing the cost of adaptability to variable nutrients in the environment. The RNA-binding catabolite repression control (Crc) protein acts ... | ['Bacterial Proteins', 'Isoleucine', 'Leucine', 'Nuclear Magnetic Resonance, Biomolecular', 'Pseudomonas syringae', 'Repressor Proteins', 'Stereoisomerism', 'Valine'] | 24,496,608 | [['D12.776.097'], ['D12.125.070.577', 'D12.125.142.383'], ['D12.125.070.637', 'D12.125.142.441'], ['E05.196.867.519.550'], ['B03.440.400.425.625.625.770', 'B03.660.250.580.590.770'], ['D12.776.260.703', 'D12.776.930.780'], ['G02.607.445.682'], ['D12.125.070.950', 'D12.125.142.930']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Methods and statistics for combining motif match scores. | Position-specific scoring matrices are useful for representing and searching for protein sequence motifs. A sequence family can often be described by a group of one or more motifs, and an effective search must combine the scores for matching a sequence to each of the motifs in the group. We describe three methods for c... | ['Algorithms', 'Databases, Factual', 'Models, Theoretical', 'Proteins', 'Sequence Alignment', 'Sequence Homology, Amino Acid', 'Software'] | 9,672,829 | [['G17.035', 'L01.224.050'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E05.599'], ['D12.776'], ['E05.393.751'], ['G02.111.810.200', 'G05.810.200'], ['L01.224.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Characterization of a half-apo derivative of peptidylglycine monooxygenase. Insight into the reactivity of each active site copper. | A derivative of peptidylglycine monooxygenase which lacks the CuH center has been prepared and characterized. This form of the enzyme is termed the half-apo protein. Copper-to-protein stoichiometric measurements establish that the protein binds only one of the two copper centers (CuM and CuH) found in the native enzyme... | ['Animals', 'Apoenzymes', 'Binding Sites', 'CHO Cells', 'Carbon Monoxide', 'Copper', 'Cricetinae', 'Mixed Function Oxygenases', 'Multienzyme Complexes', 'Oligopeptides', 'Oxygen Consumption', 'Spectrophotometry, Infrared', 'Spectrum Analysis', 'Substrate Specificity', 'X-Rays'] | 11,389,601 | [['B01.050'], ['D08.811.255.500', 'D12.776.070.290'], ['G02.111.570.120'], ['A11.251.210.200', 'A11.436.155'], ['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['B01.050.150.900.649.313.992.635.075.250'], ['D08.811.682.690.708'], ['D05.500.562', 'D08.811.600'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Epidural analgesia in the treatment of the pain syndrome in degenerative dystrophic disorders of the lumbar spine]. | Epidural analgesia (EA) with dicaine and morphine has been compared in 34 patients with pain syndrome caused by degenerative dystrophy of lumbar vertebrae. The advantages of EA with dicaine have been observed. 35.3% of patients have been subject to surgery. In the rest of patients pain syndrome was relieved. Radionucli... | ['Adult', 'Analgesia, Epidural', 'Female', 'Humans', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Osteoarthritis', 'Pain', 'Tetracaine'] | 2,629,544 | [['M01.060.116'], ['E03.091.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['C05.550.114.606', 'C05.799.613'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['D02.241.223.100.050.500.968', 'D02.455.426.559.389.127.020.937.968']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Acoustic diagnosis of elastic properties of human tooth by 320 MHz scanning acoustic microscopy after radiotherapy treatment for head and neck cancer. | BACKGROUND: On the elastic profiles of human teeth after radiotherapy for head and neck cancers, generation of dental complications, which may bring several side effects preventing the quality of life, has not well clarified. Thus, we aimed to show the applicability of using 320 MHz Scanning Acoustic Microscopy (SAM) i... | ['Adolescent', 'Adult', 'Case-Control Studies', 'Elasticity', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Male', 'Microscopy, Acoustic', 'Middle Aged', 'Organs at Risk', 'Prognosis', 'Prospective Studies', 'Quality of Life', 'Radiation Injuries', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'R... | 32,066,465 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G01.374.590'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.370', 'E01.370.350.850.565', 'E05.595.370'], ['M01.060.116.630'], ['A01.635'], ['E01.789'], ['E05.318.372... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Quenching effect of triethylamine on peroxyoxalate chemiluminescence in the presence of 7-amino-4-trifluoromethylcumarin. | The quenching effect of triethylamine on strong chemiluminescence of bis-(2,4,6-trichlorophenyl)oxalate-hydrogen peroxide system in the presence of 7-amino-4-trifluoromethylcumarin was studied. The system resulted in a nice Stern-Volmer plot with a kQ value of 1.07 x 10(-3) M(-1), in the quencher concentration range of... | ['Coumarins', 'Ethylamines', 'Fluorescence', 'Kinetics', 'Luminescent Measurements', 'Models, Chemical', 'Oxalates', 'Spectrometry, Fluorescence'] | 11,767,829 | [['D03.383.663.283.446', 'D03.633.100.150.446'], ['D02.092.471'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['G01.374.661', 'G02.111.490'], ['E05.196.712.516'], ['E05.599.495'], ['D02.241.081.337.593'], ['E05.196.712.516.600.676', 'E05.196.867.726']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Improvement of lysine production by analog-sensitive and auxotroph mutants of the acetylene-utilizing bacterium Gordona bronchialis (Rhodococcus bronchialis). | An acetylene utilizing Gordona (Rhodococcus) bronchialis strain, screened for the production of fine chemicals, was found to be capable of producing small amounts of lysine. Attempts to produce amino-acid analog-resistant and/or sensitive mutants and auxotrophs of this strain with increased lysine production were made ... | ['Acetylene', 'Asparagine', 'Cysteine', 'Drug Resistance, Microbial', 'Lysine', 'Mutation', 'Pyruvates', 'Rhodococcus'] | 9,276,926 | [['D02.455.326.397.259'], ['D12.125.068.060', 'D12.125.095.165', 'D12.125.154.049'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['G06.225', 'G07.690.773.984.269'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['G05.365.590'], ['D02.241.755.812'], ['B03.510.024.981.775']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Examining the relationship between antihypertensive medication satisfaction and adherence in older patients. | BACKGROUND: The relationship between medication adherence and treatment satisfaction has been consistently positive, however, this relationship has not been examined among older adults with hypertension.OBJECTIVES: The aim of this study was to examine the relationship between medication adherence and treatment satisfac... | ['Aged', 'Aged, 80 and over', 'Antihypertensive Agents', 'Cross-Sectional Studies', 'Female', 'Health Literacy', 'Health Surveys', 'Humans', 'Hypertension', 'Linear Models', 'Male', 'Medication Adherence', 'Middle Aged', 'Patient Satisfaction', 'Quality of Life', 'Surveys and Questionnaires', 'Tennessee'] | 27,493,129 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.411.162'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I02.233.332.186.500', 'L01.143.450.500', 'N02.421.726.407.229.500'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Geogr... | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Thymidylate synthesis and utilization via the de novo pathway in normal and megaloblastic human bone marrow cells. | We have measured the thymidylate synthetase activity of intact bone marrow cells using a 3H2O release assay. The mean thymidylate synthetase activity of vitamin B12- or folate-deficient megaloblastic marrow cells was reduced only in severely anaemic patients. There was a correlation between thymidylate synthetase activ... | ['Anemia, Macrocytic', 'Anemia, Megaloblastic', 'Bone Marrow', 'DNA', 'Deoxyuridine', 'Erythrocyte Count', 'Erythrocytes, Abnormal', 'Folic Acid Deficiency', 'Humans', 'Kinetics', 'Megaloblasts', 'Thymidine Monophosphate', 'Thymidylate Synthase', 'Thymine Nucleotides', 'Vitamin B 12 Deficiency'] | 2,721,662 | [['C15.378.071.252'], ['C15.378.071.252.196'], ['A15.382.216'], ['D13.444.308'], ['D03.383.742.680.852.300', 'D13.570.230.430', 'D13.570.685.852.300'], ['E01.370.225.500.195.107.330', 'E01.370.225.625.107.330', 'E05.200.500.195.107.330', 'E05.200.625.107.330', 'E05.242.195.107.330', 'G04.140.107.330', 'G09.188.105.330'... | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Relationship between fatty acids of adipose tissue and plasma cholesterol. | The fatty acid composition of adipose tissue from normal and hypercholesterolemic men and women was studied. We found a difference in the fatty acid composition between both sexes. A decrease in linoleic acid was found in hypercholesterolemic men, while there was an increase in palmitic and totally saturated acids in w... | ['Adipose Tissue', 'Adult', 'Aged', 'Analysis of Variance', 'Fatty Acids', 'Fatty Acids, Unsaturated', 'Humans', 'Hypercholesterolemia', 'Linoleic Acids', 'Middle Aged', 'Myristic Acids', 'Oleic Acids', 'Palmitic Acids', 'Sex Factors', 'Stearic Acids'] | 1,218,738 | [['A10.165.114'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D10.251'], ['D10.251.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.584.500.500.396'], ['D10.251.355.310.515', 'D10.251.355.343.500'], ['M01.060.116.630'], ['D10.251.640'], ['D... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pharmacist-led intervention study to improve inhalation technique in asthma and COPD patients. | UNLABELLED: RATIONAL AND AIMS: Inhaled therapy is the mainstay of treatment in patients with asthma and chronic obstructive pulmonary disease (COPD). For effectiveness of pharmacotherapy, correct use of medication is required. The aims of this study were to survey the quality of inhalation technique in patients and to ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Asthma', 'Drug Therapy', 'Female', 'Germany', 'Humans', 'Male', 'Middle Aged', 'Pharmacists', 'Professional Role', 'Prospective Studies', 'Pulmonary Disease, Chronic Obstructive', 'Quality Assurance, Health Care', 'Respiratory Therapy', 'Treatment Outcome', 'Young A... | 20,807,295 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E02.319'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.526.485.780', 'N02.360.780'], ['F01.829.316.616.625'], ['E0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Fourier transform infrared spectroscopic analysis of normal and torn rotator-cuff tendons. | We have used Fourier transform infrared spectroscopy (FTIR) to characterise the chemical and structural composition of the tendons of the rotator cuff and to identify structural differences among anatomically distinct tears. Such information may help to identify biomarkers of tears and to provide insight into the rates... | ['Aged', 'Aged, 80 and over', 'Arthroscopy', 'Collagen', 'Humans', 'Middle Aged', 'Rotator Cuff', 'Rotator Cuff Injuries', 'Spectroscopy, Fourier Transform Infrared', 'Tendon Injuries', 'Trauma Severity Indices'] | 21,357,960 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['D05.750.078.280', 'D12.776.860.300.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.567.912', 'A02.880.700'], ['C26.761.340', 'C26.803.063', 'C26.874.400'], ['E05.196.712.726... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Social exclusion and community in an urban retirement village. | Large purpose-built retirement complexes including continuing care options are increasingly popular ways to 'age in place' for older people in New Zealand and internationally. Promoted by their corporate owners as a lifestyle choice offering a wealth of activities and social interaction in manicured settings along with... | ['Aged', 'Aged, 80 and over', 'Female', 'Health Status', 'Housing for the Elderly', 'Humans', 'Interpersonal Relations', 'Male', 'Motivation', 'New Zealand', 'Psychological Distance', 'Residence Characteristics', 'Retirement', 'Social Participation', 'Social Stigma', 'Urban Health'] | 31,229,215 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['J03.340.260', 'N01.224.791.400.410', 'N06.230.150.360.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F01.658', 'F01.752.543.500.750'], ['Z01.639.760.747', 'Z01.678.100.747'], ['F01.145.813... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Modulation of histamine type II receptors on CD8+ T cells by interleukin-2 and cimetidine. | CD8+ T cells are known to play a major role in regulating immune functions under normal and disease conditions. In this study a radioligand binding assay was used to quantitate histamine type II (H2) receptors on activated T cells. The objective was to examine the expression of H2 receptors on T cells during activation... | ['Antibody Formation', 'CD8 Antigens', 'Cells, Cultured', 'Cimetidine', 'Concanavalin A', 'Humans', 'Interleukin-2', 'Receptors, Histamine H2', 'Receptors, Interleukin-2', 'T-Lymphocyte Subsets', 'T-Lymphocytes, Regulatory'] | 1,533,853 | [['G12.450.050.370.250'], ['D23.050.301.264.894.108', 'D23.101.100.894.108'], ['A11.251'], ['D02.078.370.200', 'D03.383.129.308.130'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.7... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Limits on reacquisition of song in adult zebra finches exposed to white noise. | Zebra finches (Taeniopygia guttata) learn a specific song pattern during a sensitive period of development, after which song changes little or not at all. However, recent studies have demonstrated substantial behavioral plasticity in song behavior during adulthood under a range of conditions. The current experiment exa... | ['Age Factors', 'Animals', 'Auditory Perception', 'Convalescence', 'Environmental Exposure', 'Evoked Potentials, Auditory, Brain Stem', 'Feedback, Psychological', 'Finches', 'Learning', 'Male', 'Neuronal Plasticity', 'Noise', 'Species Specificity', 'Stereotyped Behavior', 'Vocalization, Animal'] | 15,229,232 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['F02.463.593.071', 'G07.888.125'], ['C23.550.291.562'], ['N06.850.460.350'], ['G07.265.216.500.370.300', 'G07.888.250.300', 'G11.561.200.500.370.300'], ['F01.058.288', 'F04.754.308'], ['B01.050.150.900.248.620.750.250'], ['F02.463.425', 'F02.784.629.529'], ['G11.56... | ['Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Sensitive detection of Mycobacterium avium subsp. paratuberculosis in bovine semen by real-time PCR. | AIMS: To develop a fast and sensitive protocol for detection of Mycobacterium avium subsp. paratuberculosis (MAP) in bovine semen and to make a critical evaluation of the analytical sensitivity.METHODS AND RESULTS: Processed semen was spiked with known amounts of MAP. Semen from different bulls as well as semen of diff... | ['Animals', 'Bacteriological Techniques', 'Cattle', 'DNA, Bacterial', 'Immunomagnetic Separation', 'Male', 'Mycobacterium avium subsp. paratuberculosis', 'Polymerase Chain Reaction', 'Semen', 'Sensitivity and Specificity'] | 16,630,010 | [['B01.050'], ['E01.370.225.875.150', 'E05.200.875.150'], ['B01.050.150.900.649.313.500.380.271'], ['D13.444.308.212'], ['E02.095.437', 'E05.200.500.363.441', 'E05.242.363.441'], ['B03.510.024.962.500.300.600', 'B03.510.460.400.410.552.552.300.600'], ['E05.393.620.500'], ['A12.200.732'], ['E05.318.370.800', 'E05.318.74... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cooperative enhancement of water binding to crownophane by multiple hydrogen bonds: analysis by high level ab initio calculations. | The intermolecular interaction energy of the model system of the water-crownophane complex was analyzed. The water molecule has four hydrogen bonds, with the two hydrogen-donating phenolic hydroxy groups and two hydrogen-accepting oxygen atoms of the poly-oxyethylene chain of the crownophane in the complex. The MP2/6-3... | ['Crystallography, X-Ray', 'Hydrogen Bonding', 'Models, Chemical', 'Polyethylene Glycols', 'Water'] | 11,457,191 | [['E05.196.309.742.225'], ['G02.282'], ['E05.599.495'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Relationship of QT interval duration with carotid intima media thickness in a clinically healthy population undergoing cardiovascular risk screening. | OBJECTIVES: To investigate the relationship between cardiac repolarization (QT interval duration) and intima media thickness (IMT) of the carotid arteries as surrogate measures of subclinical atherosclerosis.DESIGN: Prospective study with consecutive subjects enrolled in the SAPHIR program (Salzburg Atherosclerosis Pre... | ['Adult', 'Aged', 'Arteriosclerosis', 'Body Mass Index', 'Carotid Arteries', 'Carotid Artery, Common', 'Carotid Artery, Internal', 'Electrocardiography', 'Female', 'Heart Rate', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Regression Analysis', 'Risk Factors', 'Sex Factors', 'Time Factors', 'Tunica Intima',... | 15,715,680 | [['M01.060.116'], ['M01.060.116.100'], ['C14.907.137.126'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['A07.015.114.186'], ['A07.015.114.186.200'], ['A07.015.114.186.200.230'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mitogenomic perspectives on the origin of Tibetan loaches and their adaptation to high altitude. | Tibetan loaches are the largest group of Tibetan fishes and are well adapted to the Tibetan Plateau. To investigate the origin of Tibetan loaches and their adaptations to the Tibetan Plateau, we determined 32 complete mitochondrial genomes that included 29 Tibetan loach species, two Barbatula species and Schistura long... | ['Acclimatization', 'Altitude', 'Animals', 'Cypriniformes', 'DNA, Mitochondrial', 'Evolution, Molecular', 'Genes, Mitochondrial', 'Genome, Mitochondrial', 'Phylogeny', 'Sequence Analysis, DNA', 'Species Specificity', 'Tibet'] | 27,417,983 | [['G07.025.133', 'G16.012.500.133'], ['G16.500.275.058', 'N06.230.058'], ['B01.050'], ['B01.050.150.900.493.200'], ['D13.444.308.283.225'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.024.340.365', 'G05.420.275.500'], ['G05.360.340.360'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.760.700'], ['G16.824'], ['... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Chitosan produced from Mucorales fungi using agroindustrial by-products and its efficacy to inhibit Colletotrichum species. | This study evaluated corn steep liquor (CSL) and papaya peel juice (PPJ) in mixture as substrates for the cultivation (96h, 28°C, pH 5.6, 150rpm) of Mucorales fungi for chitosan production, and determined the growth-inhibitory effect of the fungal chitosan (FuCS) obtained under optimized conditions against phytopathoge... | ['Antibiosis', 'Antifungal Agents', 'Calorimetry, Differential Scanning', 'Chitosan', 'Colletotrichum', 'Mucorales', 'Spectroscopy, Fourier Transform Infrared', 'Thermogravimetry', 'X-Ray Diffraction', 'Zea mays'] | 29,199,126 | [['G06.550.050', 'G16.062'], ['D27.505.954.122.136'], ['E05.196.131.310', 'E05.196.370.310'], ['D05.750.078.139.500', 'D09.698.211.500'], ['B01.300.381.235'], ['B01.300.300.500'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['E05.196.904'], ['E05.196.309.742', 'E05.196.822.950', 'G01.867.950', 'G02.965'], [... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phenotypical and functional differentiation of CD4+ CD45RA+ human T cells following polyclonal activation. | Human CD4+ T cells differ in their expression of the leucocyte common antigen. Antibodies detecting certain forms (CD45RA and CD45RO) of this antigen have been used to identify and isolate subpopulations of the CD4+ T cells. These isolated subsets have been shown to have different abilities concerning lymphokine produc... | ['Antigens, Differentiation', 'CD4 Antigens', 'Cell Differentiation', 'Cell Division', 'Humans', 'Leukocyte Common Antigens', 'Lymphocyte Activation', 'Phenotype', 'T-Lymphocytes'] | 2,144,907 | [['D23.050.301.264', 'D23.101.100'], ['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.301.264.894.100', 'D23.101.100.894.100'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.352.650.775... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hospital and outpatient care for psychotic patients during the last three decades. Subsequent hospital and outpatient treatment of psychotic patients hospitalized for the first time in 1949--50, 1959--60 or 1969--70. | The study deals with the development in the extent of hospital treatment and trends concerning outpatient visits for psychotics in Turku hospitalized for the first time in 1949--50 (period of shock therapy), 1959--60 (period of neuroleptics) or 1969--70 (period of intensified outpatient treatment). The bed capacity for... | ['Adolescent', 'Adult', 'Aged', 'Community Mental Health Centers', 'Female', 'Finland', 'Follow-Up Studies', 'History, 20th Century', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Patient Admission', 'Patient Readmission', 'Psychiatric Department, Hospital', 'Psychotic Disorders', 'Schizophrenia', 'Utilization Re... | 7,004,091 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['N02.278.035.158'], ['Z01.542.816.186'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['M01.060.116.630... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Faecal bacterial microbiota in patients with cirrhosis and the effect of lactulose administration. | BACKGROUND: Gut microbiota may be altered in patients with cirrhosis, and may further change after administration of lactulose. We studied the composition of gut microbiota in patients with cirrhosis and assessed the effect on it of lactulose administration.METHODS: Stool specimens were collected from 35 patients with ... | ['Adult', 'Aged', 'Feces', 'Female', 'Gastrointestinal Agents', 'Gastrointestinal Microbiome', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Lactulose', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'RNA, Ribosomal, 16S'] | 29,179,682 | [['M01.060.116'], ['M01.060.116.100'], ['A12.459'], ['D27.505.954.483'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['E05.393.760.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.629.305.423', 'D09.947.750.423'], ['C06.552.630', 'C23.550.355.412'], ['M01.060.116.... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reflected reentry in nonhomogeneous ventricular muscle as a mechanism of cardiac arrhythmias. | Arrhythmogenesis in ventricular muscle exhibiting nonhomogeneous excitability was studied in isolated tissues from feline and canine hearts. Longitudinal bundles were mounted in a three-chambered bath and simultaneous transmembrane recordings were obtained from fibers in each chamber. Nonhomogeneous excitability was es... | ['Action Potentials', 'Animals', 'Arrhythmias, Cardiac', 'Cardiac Pacing, Artificial', 'Cats', 'Dogs', 'Electrophysiology', 'Heart Ventricles', 'In Vitro Techniques', 'Membrane Potentials', 'Myocardial Contraction', 'Papillary Muscles'] | 6,689,641 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['C14.280.067', 'C23.550.073'], ['E02.331.200'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['B01.050.150.900.649.313.750.250.216.200'], ['H01.158.344.528', 'H01.158.782.236'], ['A07.541.560'], ['E05.481'], ['G01.154.535', 'G04.580', 'G07.265.67... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The Effect of Hormonal Contraception and Menstrual Cycle Timing on Genital Herpes Simplex Virus-2 Shedding and Lesions. | BACKGROUND: The effect of female sex hormones on herpes simplex virus (HSV)-2 shedding and lesion frequency is poorly understood. Previous studies suggest that hormonal contraception may increase the frequency of HSV-2 shedding.METHODS: We studied HSV-2 seropositive women who performed daily genital swabbing for HSV DN... | ['Adult', 'DNA, Viral', 'Female', 'Genitalia, Female', 'Herpes Genitalis', 'Herpesvirus 2, Human', 'Hormonal Contraception', 'Humans', 'Menstrual Cycle', 'Middle Aged', 'Statistics, Nonparametric', 'Virus Shedding', 'Young Adult'] | 30,148,758 | [['M01.060.116'], ['D13.444.308.568'], ['A05.360.319'], ['C01.221.812.640.350', 'C01.778.640.350', 'C01.925.256.466.382.290', 'C01.925.813.350', 'C12.294.329', 'C13.351.500.342'], ['B04.280.382.100.750.440'], ['E02.875.194.581'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.605'], ['M01.060.116.630'], ['E... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hypoxic remodelling of Ca2+ mobilization in type I cortical astrocytes: involvement of ROS and pro-amyloidogenic APP processing. | Chronic hypoxia (CH) alters Ca2+ homeostasis in various cells and may contribute to disturbed Ca2+ homeostasis of Alzheimer's disease. Here, we have employed microfluorimetric measurements of [Ca2+]i to investigate the mechanism underlying augmentation of Ca2+ signalling by chronic hypoxia in type I cortical astrocytes... | ['Alzheimer Disease', 'Amyloid Precursor Protein Secretases', 'Amyloid beta-Peptides', 'Amyloid beta-Protein Precursor', 'Animals', 'Animals, Newborn', 'Ascorbic Acid', 'Astrocytes', 'Blotting, Western', 'Bradykinin', 'Calcium', 'Cell Hypoxia', 'Cells, Cultured', 'Cerebral Cortex', 'Disease Models, Animal', 'Dose-Respo... | 14,756,807 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D08.811.277.656.300.032'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['D12.776.049.407.249', 'D12.776.543.039', 'D12.776.645.468.500', 'D12.776.811.050'], ['B01.050'], ['B01.050.050.282'], ['D02.241.081.844.107', 'D02.241.511.902... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Differences in heart rate variability during haemodialysis and haemofiltration. | BACKGROUND: The aim of our study was to evaluate whether convective (haemofiltration, Hf) and diffusive (haemodialysis, Hd) dialysis techniques induce different patterns of long- and short-term autonomic adjustments in haemodynamically stable dialysis patients.METHODS: Ten haemodynamically stable Hd patients were studi... | ['Aged', 'Body Weight', 'Diffusion', 'Electrocardiography', 'Female', 'Heart Rate', 'Hemofiltration', 'Humans', 'Kinetics', 'Male', 'Middle Aged', 'Oscillometry', 'Renal Dialysis', 'Sodium', 'Systole'] | 17,400,561 | [['M01.060.116.100'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G01.202', 'G02.196'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.600.875.500', 'G09.330.380.500'], ['E02.870.225', 'E04.292.471'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A simplified computer model of cardiovascular system with an arm branch. | Non-invasive pressure simulators that regenerate oscillometric waveforms promise an alternative to expensive clinical trials for validating oscillometric noninvasive blood pressure devices. However, existing simulators only provide oscillometric pressure in cuff and thus have a limited accuracy. It is promising to buil... | ['Aorta', 'Arterial Pressure', 'Blood Flow Velocity', 'Blood Pressure Determination', 'Blood Viscosity', 'Brachial Artery', 'Computer Simulation', 'Humans', 'Models, Cardiovascular', 'Pulsatile Flow'] | 25,226,957 | [['A07.015.114.056'], ['G09.330.380.076.347'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.370.140', 'E01.370.600.100'], ['G09.188.370.124', 'G09.330.380.630.110'], ['A07.015.114.139'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.161'], ['G01.482.620', 'G09.330.380.630.555'... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo. | In Xenopus and zebrafish embryos, elongation of the anterior-posterior body axis depends on convergent extension, a process that involves polarized cell movements and is regulated by non-canonical Wnt signaling. The mechanisms that control axis elongation of the mouse embryo are much less well understood. Here, we char... | ['Alleles', 'Animals', 'Body Patterning', 'Carrier Proteins', 'Cell Movement', 'Embryo, Mammalian', 'Mice', 'Morphogenesis', 'Mutation', 'Nuclear Proteins', 'Protein Structure, Tertiary', 'Signal Transduction', 'Wnt Proteins', 'Zinc Fingers'] | 18,701,545 | [['G05.360.340.024.340.030'], ['B01.050'], ['G07.345.500.100'], ['D12.776.157'], ['G04.198', 'G07.568.500.180'], ['A16.254'], ['B01.050.150.900.649.313.992.635.505.500'], ['G07.345.500'], ['G05.365.590'], ['D12.776.660'], ['G02.111.570.820.709.610'], ['G02.111.820', 'G04.835'], ['D12.776.467.984', 'D23.529.984'], ['G02... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prostacyclin treatment in severe traumatic brain injury: a microdialysis and outcome study. | UNLABELLED: Prostacyclin (PGI(2)) is a potent vasodilator, inhibitor of leukocyte adhesion, and platelet aggregation. In trauma the balance between PGI(2) and thromboxane A(2) (TXA(2)) is shifted towards TXA(2). Externally provided PGI(2) would, from a theoretical and experimental point of view, improve the microcircul... | ['Adolescent', 'Adult', 'Aged', 'Brain Injuries', 'Double-Blind Method', 'Epoprostenol', 'Female', 'Humans', 'Injury Severity Score', 'Intracranial Pressure', 'Male', 'Microdialysis', 'Middle Aged', 'Platelet Aggregation Inhibitors', 'Prospective Studies', 'Treatment Outcome', 'Vasodilator Agents'] | 19,226,191 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D10.251.355.255.550.550.500', 'D23.469.050.175.725.550.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Glycinergic inhibition in thalamus revealed by synaptic receptor blockade. | Using juvenile rat brain slices, we examined the possibility that strychnine-sensitive receptors for glycine-like amino acids contributed to synaptic inhibition in ventrobasal thalamus, where gamma-aminobutyrate (GABA) is the prevalent inhibitory transmitter. Ventrobasal nuclei showed staining for antibodies against al... | ['Animals', 'Dose-Response Relationship, Drug', 'Electric Stimulation', 'Excitatory Postsynaptic Potentials', 'GABA Antagonists', 'Glycine', 'Glycine Agents', 'Immunohistochemistry', 'In Vitro Techniques', 'Male', 'Membrane Potentials', 'Neurotransmitter Agents', 'Patch-Clamp Techniques', 'Rats', 'Rats, Sprague-Dawley'... | 15,993,440 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.723.402'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['D27.505.519.625.240.300', 'D27.505.696.577.240.300'], ['D12.125.481'], ['D27.505.519.625.300', 'D27.505.696.577.300'], ['E01.370.225.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of evidential reasoning and AHP to assess regional industrial safety. | China's fast economic growth contributes to the rapid development of its urbanization process, and also renders a series of industrial accidents, which often cause loss of life, damage to property and environment, thus requiring the associated risk analysis and safety control measures to be implemented in advance. Howe... | ['Accident Prevention', 'Accidents', 'Beijing', 'Economic Development', 'Humans', 'Industrial Development', 'Models, Statistical', 'Occupational Health', 'Risk Assessment', 'Risk Factors', 'Urbanization'] | 29,795,593 | [['N06.850.135.060'], ['N06.850.135'], ['Z01.252.474.164.225', 'Z01.433.114'], ['I01.261.262', 'N03.219.206'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.261.262.500', 'J01.576.519'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['N01.400.525'], ['E05.318.740.600.800.715... | ['Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Sensitivity and specificity of multiphoton laser tomography for in vivo and ex vivo diagnosis of malignant melanoma. | The incidence of malignant melanoma has shown a dramatic increase over the past three decades. Patient outcome and curability depend on early diagnosis. In vivo multiphoton laser tomography represents a recently developed diagnostic tool that allows non-invasive tissue imaging. We aim to demonstrate the application of ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Biopsy', 'Child', 'Child, Preschool', 'Dendritic Cells', 'Female', 'Humans', 'Lasers', 'Logistic Models', 'Male', 'Melanocytes', 'Melanoma', 'Microscopy, Fluorescence, Multiphoton', 'Middle Aged', 'Nevus, Pigmented', 'Observer Variation', 'Reproducibility of Results... | 19,177,136 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['M01.060.406'], ['M01.060.406.448'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Clinical value of seminal paraoxonase-1 activity evaluation in the diagnosis of male infertility]. | OBJECTIVE: To investigate the changes in seminal paraoxonase-1 (PON-1) activity in infertile male patients and assess the clinical value of seminal PON-1 examination in the diagnosis of male infertility.METHODS: Seminal PON-1 activity was detected by spectrophotometric method in the semen samples from 270 infertile mal... | ['Adult', 'Aryldialkylphosphatase', 'Case-Control Studies', 'Humans', 'Infertility, Male', 'Male', 'Semen', 'Semen Analysis', 'Young Adult'] | 22,985,582 | [['M01.060.116'], ['D08.811.277.352.660.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365.700'], ['A12.200.732'], ['E01.370.225.992', 'E05.200.992'], ['M01.060.116.815']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
MIF gene polymorphisms confer susceptibility to Vogt-Koyanagi-Harada syndrome in a Han Chinese population. | PURPOSE: The aim of the study was to determine the association of macrophage migration inhibitory factor (MIF) gene polymorphisms with Vogt-Koyanagi-Harada (VKH) syndrome.METHODS: A total of 600 Han Chinese VKH patients and 600 healthy controls were genotyped for rs755622 and rs2096525 of MIF by PCR-restriction fragmen... | ['Adult', 'Alleles', 'Asian Continental Ancestry Group', 'China', 'DNA', 'Female', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Intramolecular Oxidoreductases', 'Macrophage Migration-Inhibitory Factors', 'Male', 'Polymorphism, Genetic', 'Uveomeningoencephalitic Syndrome'] | 24,194,192 | [['M01.060.116'], ['G05.360.340.024.340.030'], ['M01.686.508.200'], ['Z01.252.474.164'], ['D13.444.308'], ['G05.330'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.399.475'], ['D12.644.276.374.480.625', 'D12.776.467.374.480.625', 'D23.125.477.500', 'D23... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Patch choice under predation hazard. | In this paper we study optimal animal movement in heterogeneous environments consisting of several food patches in which animals trade-off energy gain versus predation risk. We derive a myopic optimization rule describing optimal animal movements by fitness maximization assuming an animal state is described by a single... | ['Animals', 'Behavior, Animal', 'Choice Behavior', 'Feeding Behavior', 'Linear Models', 'Models, Psychological', 'Mortality', 'Population Density', 'Predatory Behavior', 'Predictive Value of Tests', 'Reproduction', 'Time Factors'] | 11,162,791 | [['B01.050'], ['F01.145.113'], ['F02.463.785.373.346'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['E05.599.695'], ['E05.318.308.985... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Unconventional transmissible agents or prions]. | Unconventional transmissible agents, or prions, induce rare, slow, neurodegenerative diseases that are transmissible and always fatal: transmissible subacute spongiform encephalopathies. These diseases are characterised by spongiosis associated with gliosis without inflammation or demyelination. These unconventional tr... | ['Humans', 'Models, Biological', 'Prion Diseases', 'Prions'] | 7,939,297 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['C01.207.800', 'C10.228.228.800', 'C10.574.843'], ['D12.776.785']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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