Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Suppression of lymphocyte signal transduction by murine mastocytoma ascites. | The lymphocyte signal transduction, as determined by intracellular free Ca2+ mobilization of concanavalin A-stimulated T lymphocytes and of anti-immunoglobulin mu chain antibody-stimulated B lymphocytes, was suppressed in spleen cells from mice injected with murine P1.HTR mastocytoma-induced ascites and in spleen cells... | ['Animals', 'Ascites', 'B-Lymphocytes', 'Calcium', 'Concanavalin A', 'Immunoglobulin mu-Chains', 'Immunosuppression', 'Lymphocyte Activation', 'Lymphocytes', 'Mast-Cell Sarcoma', 'Mice', 'Mice, Inbred Strains', 'Neoplasms, Experimental', 'Signal Transduction', 'Suppressor Factors, Immunologic', 'T-Lymphocytes'] | 1,808,472 | [['B01.050'], ['C23.550.081'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['D12.776.124.486.485.114.619.574.500', 'D12.776.124.486.485.705.... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Measurement of arachidonic acid release from human polymorphonuclear neutrophils and platelets: comparison between gas chromatographic and radiometric assays. | a simple gas chromatographic method for the assay of phospholipase A2 (PLA2) has been described in which arachidonic acid released from endogenous phospholipid pools is measured following its extraction and derivatization to pentafluorobenzyl esters. Using this assay, PLA2 activities in control and calcium ionophore-st... | ['Acetophenones', 'Arachidonic Acids', 'Blood Platelets', 'Calcimycin', 'Chromatography, Gas', 'Fatty Acids, Unsaturated', 'Humans', 'Kinetics', 'Neutrophils', 'Phospholipases A', 'Phospholipases A2', 'Serum Albumin, Bovine', 'Tritium'] | 2,048,718 | [['D02.522.120'], ['D10.251.355.255.100', 'D10.251.355.310.166'], ['A11.118.188', 'A15.145.229.188'], ['D03.633.100.221.173'], ['E05.196.181.349'], ['D10.251.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Monoamine metabolites in the CSF of epileptic patients. | To assess the possible role of amine neurotransmitters in human epilepsy, we measured metabolites of serotonin (5-hydroxyindoleacetic acid [5-HIAA]), dopamine (homovanillic acid [HVA]), and norepinephrine (3-methoxy-4-hydroxyphenylethylene glycol [MHPG]) in the lumbar cerebrospinal fluid (CSF) of patients with partial ... | ['Adolescent', 'Adult', 'Child', 'Epilepsy', 'Female', 'Glycols', 'Homovanillic Acid', 'Humans', 'Hydroxyindoleacetic Acid', 'Male', 'Methoxyhydroxyphenylglycol', 'Middle Aged', 'Neurotransmitter Agents', 'Phenylacetates', 'Pneumoencephalography', 'Spinal Puncture'] | 37,460 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Physical experience leads to enhanced object perception in parietal cortex: insights from knot tying. | What does it mean to "know" what an object is? Viewing objects from different categories (e.g., tools vs. animals) engages distinct brain regions, but it is unclear whether these differences reflect object categories themselves or the tendency to interact differently with objects from different categories (grasping too... | ['Adolescent', 'Adult', 'Analysis of Variance', 'Brain Mapping', 'Discrimination, Psychological', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Linguistics', 'Magnetic Resonance Imaging', 'Male', 'Motor Skills', 'Names', 'Neuropsychological Tests', 'Oxygen', 'Parietal Lobe', 'Photic Stimulation', 'Reactio... | 23,022,108 | [['M01.060.057'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.593.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['L01.559.598'], ['E01.370.350.825.500'], ['F02.808.260'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Physiotherapy and muscle dysfunction]. | This article gives information about the role of the physiotherapist on the patient with a craniomandibular dysfunction, caused by a masticatory muscle dysfunction. The approach of the physiotherapist is discussed and information about the relevant etiological factors and symptoms are described. The diagnostic procedur... | ['Adolescent', 'Female', 'Humans', 'Masticatory Muscles', 'Physical Therapy Modalities', 'Temporomandibular Joint Dysfunction Syndrome'] | 2,639,261 | [['M01.060.057'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.567.600', 'A14.530'], ['E02.779', 'E02.831.535'], ['C05.500.607.221.897.897', 'C05.550.905.905', 'C05.651.243.897.897', 'C05.651.550.905', 'C07.320.610.291.897.897', 'C07.678.949']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Junior doctor strike model of care: Reduced access block and predominant Fellow of the Australasian College for Emergency Medicine staffing improve emergency department performance. | OBJECTIVE: To describe the response and analyse ED performance during a 5-day junior doctor strike.METHODS: Data were collected via the patient information management computer system. Key performance indicators included percentage seen within maximum waiting times per triage category (TC), ED length of stay, emergency ... | ['Australia', 'Bed Occupancy', 'Efficiency, Organizational', 'Emergency Service, Hospital', 'Health Services Accessibility', 'Humans', 'Length of Stay', 'Quality of Health Care', 'Retrospective Studies', 'Schools, Medical'] | 18,973,640 | [['Z01.639.100', 'Z01.678.100.373'], ['N02.278.050'], ['N04.452.209.500'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['N04.761', 'N05.715'], ['E05.318.372.500... | ['Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[The level of lipid peroxidation products and the parameters of antioxidative defense in the expired air condensate in patients with respiratory tuberculosis]. | The paper presents the data of examination of three groups of patients with pulmonary tuberculosis: 25 with a relatively favorable course of the disease, 26 with acutely progressive tuberculosis, pneumoperitoneum along with chemotherapy was used in complex therapy in 10 of them. The parameters of lipid peroxidation wer... | ['Adult', 'Antioxidants', 'Female', 'Humans', 'Lipid Peroxidation', 'Male', 'Middle Aged', 'Tuberculosis, Pulmonary'] | 15,532,467 | [['M01.060.116'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.515', 'G03.295.531.587'], ['M01.060.116.630'], ['C01.150.252.410.040.552.846.899', 'C01.748.939', 'C08.381.922', 'C08.730.939']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The Nrf2 activator tBHQ inhibits T cell activation of primary human CD4 T cells. | The transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) regulates a battery of antioxidant, detoxification, and cell stress genes. It is activated by oxidative stress and a number of exogenous compounds, one of which is tert-butylhydroquinone (tBHQ), a widely used food preservative. Nrf2 modulates i... | ['Antigens, CD', 'Antigens, Differentiation, T-Lymphocyte', 'Antioxidants', 'CD28 Antigens', 'CD3 Complex', 'CD4-Positive T-Lymphocytes', 'Cytokines', 'DNA', 'Dose-Response Relationship, Drug', 'Flow Cytometry', 'Humans', 'Hydroquinones', 'Interleukin-2 Receptor alpha Subunit', 'Lectins, C-Type', 'Leukocytes, Mononucle... | 25,484,350 | [['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.894', 'D23.101.100.894'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D12.776.543.750.705.222.500', 'D23.050.301.264.894.128', 'D23.101.100.894.128'], ['D23.050.301.264.894.095', 'D23.101.100.894.095'], ['A11.118.637.555.567.569.200', '... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Junctional arrhythmias in radiofrequency modification of the atrioventricular node]. | UNLABELLED: Accelerated junctional rhythm (JR) is known as a response of the atrioventricular node to thermal injury and a common finding in radiofrequency ablation for AV node reentrant tachycardia. We studied JR during 1314 radiofrequency current deliveries in 172 patients with AV node reentrant tachycardia or paroxy... | ['Adult', 'Aged', 'Atrial Fibrillation', 'Atrioventricular Node', 'Bundle of His', 'Catheter Ablation', 'Electrocardiography', 'Female', 'Heart Block', 'Humans', 'Male', 'Middle Aged', 'Tachycardia, Atrioventricular Nodal Reentry', 'Tachycardia, Ectopic Junctional'] | 8,578,794 | [['M01.060.116'], ['M01.060.116.100'], ['C14.280.067.198', 'C23.550.073.198'], ['A07.541.409.147'], ['A07.541.409.273'], ['E02.808.750.500', 'E04.014.760.500'], ['E01.370.370.380.240', 'E01.370.405.240'], ['C14.280.067.558', 'C14.280.123.500', 'C23.550.073.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.0... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reversibility of the covalent reaction of CC-1065 and analogues with DNA. | Covalent DNA adducts of the antitumor antibiotic CC-1065 and its analogues undergo a retrohomologous Michael reaction in aqueous/organic solvent mixtures to regenerate the initial cyclopropylpyrroloindole (CPI) structure and, presumably, intact DNA. This reaction, which at higher temperatures competes with depurination... | ['Alkylation', 'Animals', 'Antibiotics, Antineoplastic', 'Benzofurans', 'Cattle', 'Cell Survival', 'Circular Dichroism', 'Cyclohexanecarboxylic Acids', 'Cyclohexenes', 'DNA', 'Duocarmycins', 'Indoles', 'Leucomycins', 'Leukemia L1210', 'Molecular Structure', 'Solutions', 'Spectrophotometry, Ultraviolet', 'Tritium', 'Tum... | 1,547,233 | [['G02.111.035', 'G02.607.094', 'G03.059'], ['B01.050'], ['D27.505.954.248.106'], ['D03.633.100.127'], ['B01.050.150.900.649.313.500.380.271'], ['G04.346'], ['E05.196.867.151'], ['D02.241.223.268', 'D02.455.426.392.368.367.218'], ['D02.455.426.392.368.367.379'], ['D13.444.308'], ['D03.383.129.578.275', 'D03.633.100.473... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Leishmania donovani: expression and characterization of Escherichia coli-expressed recombinant chitinase LdCHT1. | Leishmania parasites produce chitinase activity (EC. 3.2.1.14) thought to be important in parasite-sandfly interactions and transmission of the parasite to the vertebrate host. Previous observations have suggested that parasite chitinases are involved in degradation of the sandfly peritrophic matrix and the chitinous l... | ['Acetylglucosamine', 'Animals', 'Chitin', 'Chitinases', 'Chromatography, Gel', 'Chromatography, Thin Layer', 'Escherichia coli', 'Fluorometry', 'Gene Expression Regulation, Enzymologic', 'Hydrogen-Ion Concentration', 'Hydrolysis', 'Hymecromone', 'Leishmania donovani', 'Recombinant Proteins', 'Substrate Specificity'] | 11,888,249 | [['D09.067.342.531.050'], ['B01.050'], ['D05.750.078.139', 'D09.698.211'], ['D08.811.277.450.207'], ['E05.196.181.400.250'], ['E05.196.181.400.537'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E05.196.712.516.600'], ['G05.308.320'], ['G02.300'], ['G02.380'], ['D03.383.663.283.446.912.531', 'D03.633.100.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of vitamin B12 on the sleep-wake rhythm following an 8-hour advance of the light-dark cycle in the rat. | We have studied the effect of vitamin B12 (VB12) on the sleep-wake rhythm following an 8-h advance of the light-dark (LD) cycle in the rat. The electroencephalogram and electromyogram were recorded on chart paper via a two-channel telemetry system. Infusion of VB12 (Mecobalamin; 0.25 microgram/h) or saline into the abd... | ['Animals', 'Circadian Rhythm', 'Male', 'Rats', 'Rats, Wistar', 'Sleep', 'Vitamin B 12', 'Wakefulness'] | 9,108,574 | [['B01.050'], ['G07.180.562.190'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['F02.830.855', 'G11.561.803'], ['D03.383.129.578.840.437.777', 'D03.633.400.909.437.777', 'D04.345.783.437.777'], ['F02.830.104.821', 'G11.561.035.738']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vivo and in vitro application of near-infrared fiber optic probe for Ehrlich carcinoma distinction: Towards the development of real-time tumor margins assessment tool. | This report describes a full-scale experiment on intradermal Ehrlich carcinoma (EC) differentiation in mouse model using NIR spectroscopy in diffuse reflectance mode and chemometric data processing. EC is widely used as an experimental tumor model due to its resemblance with human undifferentiated epithelial tumors and... | ['Animals', 'Biopsy', 'Carcinoma, Ehrlich Tumor', 'Cell Proliferation', 'Female', 'Fiber Optic Technology', 'Male', 'Mice, Inbred BALB C', 'Neoplasm Staging', 'Principal Component Analysis', 'Spectroscopy, Near-Infrared', 'Support Vector Machine'] | 30,677,734 | [['B01.050'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.557.470.200.200', 'C04.619.169'], ['G04.161.750', 'G07.345.249.410.750'], ['H01.671.617.249'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[Autologous bone marrow transfusion in the treatment of adults with hematologic neoplasms. Experiences from Bern]. | 21 patients with hematological neoplasias (8 ALL, 4 AML, 4 NHL, 5 HD) were treated with high dose therapy and autologous bone marrow rescue (ABMT). At the time of ABMT 12 patients were in CR, 6 in PR and 3 in relapse. 66% of the patients were at high risk at the time of diagnosis. Before ABMT patients received an ablat... | ['Adolescent', 'Adult', 'Antineoplastic Combined Chemotherapy Protocols', 'Bone Marrow', 'Bone Marrow Transplantation', 'Combined Modality Therapy', 'Female', 'Hodgkin Disease', 'Humans', 'Leukemia', 'Leukemia, Myeloid, Acute', 'Lymphoma, Non-Hodgkin', 'Male', 'Middle Aged', 'Neoplasms', 'Precursor Cell Lymphoblastic L... | 2,667,130 | [['M01.060.057'], ['M01.060.116'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['A15.382.216'], ['E02.095.147.725.040', 'E04.936.580.040'], ['E02.186'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337'], ['C04.557.337.539.2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Immunogenicity of peptides for B cells is not impaired by overlapping T-cell epitope topology. | The epitope specificity of T-cell help to B cells and of surface immunoglobulin-mediated B-cell-binding of antigens usually involves topographically distinct antigenic determinants. The possibility of cross-recognition of the same peptide sequence by both T cells and antibodies has been a matter of conflicting opinions... | ['Amino Acid Sequence', 'Animals', 'Antigen-Presenting Cells', 'B-Lymphocytes', 'Cell Line', 'Epitope Mapping', 'Epitopes, T-Lymphocyte', 'Female', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Mice, Inbred Strains', 'Molecular Sequence Data', 'Peptides', 'T-Lymphocytes'] | 8,774,349 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A11.066', 'A15.382.066'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A11.251.210'], ['E05.478.274', 'E05.601.690.300'], ['D23.050.550.402'], ['B01.050.150.900.649.313.992.635.505.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Comparison of neural response telemetry thresholds with behavioral T/C levels]. | OBJECTIVE: To provide an objective method to estimate T-levels and C-levels using neural response telemetry (NRT) thresholds for children, from whom we can not get accurate responses because they are very young or have other disabilities, by comparing NRT thresholds and T/C levels.METHODS: Seventy patients implanted wi... | ['Adolescent', 'Adult', 'Auditory Threshold', 'Child', 'Child, Preschool', 'Cochlear Implantation', 'Cochlear Implants', 'Female', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Telemetry'] | 12,966,804 | [['M01.060.057'], ['M01.060.116'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['M01.060.406'], ['M01.060.406.448'], ['E04.580.450.220', 'E04.650.220'], ['E07.305.250.319.381.500.500', 'E07.695.150', 'E07.695.202.381.500.500', 'E07.814.458.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Retrograde transvenous neuroperfusion: a back door treatment for stroke. | BACKGROUND AND PURPOSE: Stroke is the third leading cause of death and the leading cause of adult disability in the United States. The clot-lysis drug tissue plasminogen activator is the only treatment that has been effective for acute stroke patients, yet there are significant limitations to its use and effectiveness.... | ['Animals', 'Arterial Occlusive Diseases', 'Brain', 'Brain Ischemia', 'Cerebrovascular Disorders', 'Disease Models, Animal', 'Evoked Potentials, Somatosensory', 'Male', 'Neurologic Examination', 'Papio', 'Reperfusion', 'Surgical Instruments', 'Surgical Procedures, Operative'] | 9,731,618 | [['B01.050'], ['C14.907.137'], ['A08.186.211'], ['C10.228.140.300.150', 'C14.907.253.092'], ['C10.228.140.300', 'C14.907.253'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.265.216.500.400', 'G11.561.200.500.400'], ['E01.370.376.550', 'E01.370.600.550'], ['B01.050.150.900.649.313.988.400.112.199.120.610'], ['E0... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A salicylic acid-induced lectin-like protein plays a positive role in the effector-triggered immunity response of Arabidopsis thaliana to Pseudomonas syringae Avr-Rpm1. | Salicylic acid (SA) is one of the key hormones that orchestrate the pathogen-induced immune response in plants. This response is often characterized by the activation of a local hypersensitive reaction involving programmed cell death, which constrains proliferation of biotrophic pathogens. Here, we report the identific... | ['Arabidopsis', 'Arabidopsis Proteins', 'Bacterial Proteins', 'Cell Death', 'Cell Membrane', 'Gene Expression Regulation, Plant', 'Glycoproteins', 'Lectins', 'Plant Diseases', 'Plant Immunity', 'Plant Leaves', 'Pseudomonas syringae', 'Salicylic Acid'] | 24,006,883 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['D12.776.097'], ['G04.146'], ['A11.284.149'], ['G05.308.375'], ['D09.400.430', 'D12.776.395'], ['D12.776.503'], ['G15.610'], ['G12.450.800', 'G15.630'], ['A18.024.812'], ['B03.440.400.425.625.625.770', 'B03.660.250.580.590.770'], ['D02.241.223.100.300.595.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Virtual reality videos used in undergraduate palliative and oncology medical teaching: results of a pilot study. | BACKGROUND: Virtual reality (VR) immersive environments have been shown to be effective in medical teaching. Our university hospital received funding from our deanery, Health Education in Wales, to film teaching videos with a 360-degree camera.AIMS: To evaluate whether VR is an effective and acceptable teaching environ... | ['Adult', 'Education, Medical, Undergraduate', 'Female', 'Humans', 'Male', 'Medical Oncology', 'Palliative Medicine', 'Pilot Projects', 'Videotape Recording', 'Virtual Reality', 'Wales'] | 30,808,627 | [['M01.060.116'], ['I02.358.399.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.429.515'], ['H02.403.645'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['J01.897.280.500.846.734', 'J01.897.280.500.898.840', 'L01.178.590.875.840', 'L01.178.820.090.846.734', 'L01.17... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
[Screening of prothrombotic state-related genes from human hepatic cDNA library]. | OBJECTIVE: To screen prothrombotic state-related cDNA sequences from human hepatic cDNA library.METHODS: The subtracted cDNA library for differentially expressed genes in rat liver of prothrombotic state (PTS) was constructed by suppression subtractive hybridization. Positive clones were identified by differential scre... | ['Base Sequence', 'Cloning, Molecular', 'Gene Expression Profiling', 'Gene Library', 'Humans', 'Liver', 'Molecular Sequence Data', 'Sequence Homology, Nucleic Acid', 'Thrombophilia'] | 16,235,517 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['E05.393.332'], ['G05.360.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['L01.453.245.667'], ['G02.111.810.550', 'G05.810.550'], ['C15.378.925']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Kallmann's syndrome: skeletal and psychological aspects of late diagnosis. | We report a case of Kallmann's syndrome (KS) in a previously untreated 30-year-old Caucasian male, admitted to our Endocrinology Department, presenting with hypogonadotropic hypogonadism and hypoosmia, and reporting a history of rickets in early childhood and a rapid growth pattern. On admission, his main complaints we... | ['Adult', 'Attitude to Health', 'Bone Density', 'Disease Progression', 'Humans', 'Kallmann Syndrome', 'Male'] | 14,595,239 | [['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['G11.427.100'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.706.316.096.750', 'C13.351.875.253.096.750', 'C16.131.939.316.096.750', 'C16.320.467', 'C19.391.119.096.750', 'C19.391.482.600']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reproducibility studies for anti-DNA antibody detection in systemic lupus erythematosus and related diseases. FIAX fluorometric immunoassay and Farr radioimmunoassay. | We compared the FIAX fluorometric immunoassay for antiDNA antibodies with a Farr radio-immunoassay. Neither was precise; coefficients of variation usually exceeded 10%. The 2 assays correlated well (r = 0.87). Both were almost completely specific for numbers of sera with elevated antiDNA preferable to the Farr assay an... | ['Antibodies, Antinuclear', 'Cost-Benefit Analysis', 'Epitopes', 'Fluorometry', 'Humans', 'Immunoassay', 'Lupus Erythematosus, Systemic', 'Radioimmunoassay', 'Reagent Kits, Diagnostic', 'Time Factors'] | 6,180,758 | [['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['N03.219.151.125'], ['D23.050.550'], ['E05.196.712.516.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['C17.300.480', 'C20.111.590'], ['E01.370.384.700', 'E05.478.566.639... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Prospective, age-related analysis of surgical results, functional outcome, and quality of life after ileal pouch-anal anastomosis. | OBJECTIVE To evaluate how age affects functional outcome and quality of life after ileal pouch anal anastomosis (IPAA). SUMMARY BACKGROUND DATA Because of the limited number of older patients undergoing IPAA, it has been difficult to assess functional outcome and quality of life stratified by age. METHODS IPAA was perf... | ['Adenomatous Polyposis Coli', 'Age Factors', 'Aged', 'Analysis of Variance', 'Colitis, Ulcerative', 'Colonic Neoplasms', 'Fecal Incontinence', 'Female', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Patient Satisfaction', 'Proctocolectomy, Restorative', 'Prospective Studies', 'Quality of Life', 'Surveys and Que... | 12,894,015 | [['C04.557.470.035.215.100', 'C04.588.274.476.411.307.089', 'C04.700.100', 'C06.301.371.411.307.090', 'C06.405.249.411.307.090', 'C06.405.469.158.356.090', 'C06.405.469.491.307.090', 'C06.405.469.578.249', 'C16.320.700.100'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.... | ['Diseases [C]', 'Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Cytokine responses in the Japanese pufferfish (Takifugu rubripes) head kidney cells induced with heat-killed probiotics isolated from the Mongolian dairy products. | Cytokine responses in the Japanese pufferfish (Takifugu rubripes) head kidney (HK) cells to heat-killed lactic acid bacteria probiotics isolated from the Mongolian dairy products were investigated by transcriptomic examination. The HK cells were incubated with two heat-killed bacteria, namely Lactobacillus paracasei sp... | ['Animals', 'Aquaculture', 'Cytokines', 'Dairy Products', 'Head Kidney', 'Hot Temperature', 'Lactobacillus', 'Mongolia', 'Multiplex Polymerase Chain Reaction', 'Probiotics', 'Species Specificity', 'Takifugu', 'Time Factors'] | 23,422,813 | [['B01.050'], ['J01.040.168'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G07.203.300.350', 'J02.500.350'], ['A13.449', 'A16.835.400'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B03.353.750.450.475', 'B03.510.... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Control of the dog thyrocyte plasma membrane iodide permeability by the Ca(2+)-phosphatidylinositol and adenosine 3',5'-monophosphate cascades. | Protein iodination by the dog thyrocyte (a marker of thyroid hormone synthesis) is stimulated by the Ca(2+)-phosphatidylinositol and cAMP cascades. We have shown previously that H2O2 generation, a limiting step of thyroid hormone synthesis, is modulated by these two cascades. In this work, we show that the I- release f... | ['Animals', 'Biological Transport', 'Calcium', 'Carrier Proteins', 'Cell Differentiation', 'Cell Membrane Permeability', 'Cells, Cultured', 'Cyclic AMP', 'Dogs', 'In Vitro Techniques', 'Iodides', 'Marine Toxins', 'Membrane Proteins', 'Phosphatidylinositols', 'Symporters', 'Thiazoles', 'Thyroid Gland'] | 8,070,394 | [['B01.050'], ['G03.143'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157'], ['G04.152'], ['G03.143.335', 'G04.175'], ['A11.251'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.481'], ['D01.248.4... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Actigraphic sleep-wake patterns and urinary 6-sulfatoxymelatonin excretion in patients with Alzheimer's disease. | Recent studies suggest melatonin, due to its antioxidant and free-radical-scavenging actions, may play a role in the neuroprotection against amyloid, which is implicated in the pathogenesis of Alzheimer's disease (AD). In this study, we determined urinary 6-sulfatoxymelatonin (aMT6s) excretion together with actigraphic... | ['Adult', 'Aged', 'Aging', 'Alzheimer Disease', 'Circadian Rhythm', 'Dementia', 'Female', 'Humans', 'Light', 'Male', 'Melatonin', 'Middle Aged', 'Polysomnography', 'Sleep', 'Time Factors'] | 11,475,420 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['G07.180.562.190'], ['C10.228.140.380', 'F03.615.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D03.633.100.473... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Incidence of imipenem hypersensitivity reactions in febrile neutropenic bone marrow transplant patients with a history of penicillin allergy. | The purpose of this retrospective study was to assess cross-hypersensitivity between imipenem/cilastatin and penicillin in patients with reported penicillin allergies. Medical records of febrile neutropenic, penicillin-allergic bone marrow transplant recipients who received imipenem/cilastatin treatment were retrospect... | ['Adult', 'Aged', 'Bone Marrow Transplantation', 'Cilastatin', 'Cilastatin, Imipenem Drug Combination', 'Cross Reactions', 'Drug Combinations', 'Drug Hypersensitivity', 'Fever', 'Humans', 'Imipenem', 'Incidence', 'Middle Aged', 'Neutropenia', 'Penicillins', 'Retrospective Studies'] | 11,096,026 | [['M01.060.116'], ['M01.060.116.100'], ['E02.095.147.725.040', 'E04.936.580.040'], ['D02.455.426.392.368.533.200', 'D10.251.355.325.200'], ['D02.065.589.099.124.300.500.500', 'D02.455.426.392.368.533.200.500', 'D03.633.100.300.124.300.500.500', 'D10.251.355.325.200.500', 'D26.310.356'], ['G12.122.281'], ['D26.310'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Use of electric stimulation to prevent the development of muscle changes during hypokinesia]. | An attempt was made to use electric stimulation of antigravity muscles of hind limbs of rats exposed to a 15 and 30 day hypokinesia as a method for preventing structural and metabolic disorders that develop in the muscular tissue during a diminished motor activity. The electric stimulation was carried out using the Bio... | ['Adenosine Triphosphatases', 'Animals', 'Electric Stimulation', 'Glutamate Dehydrogenase', 'Glycerolphosphate Dehydrogenase', 'Hindlimb', 'Hydroxybutyrate Dehydrogenase', 'Immobilization', 'Ketoglutarate Dehydrogenase Complex', 'L-Lactate Dehydrogenase', 'Male', 'Muscles', 'NADH, NADPH Oxidoreductases', 'Rats', 'Succi... | 234,552 | [['D08.811.277.040.025'], ['B01.050'], ['E05.723.402'], ['D08.811.682.664.500.398'], ['D08.811.682.047.150.700.400'], ['A13.473'], ['D08.811.682.047.820.350'], ['E05.472'], ['D05.500.562.468', 'D08.811.600.465', 'D08.811.682.657.350.750'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['A02.633', 'A10.690'], ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bile induced acute oedematous pancreatitis in rats: non-parallel changes in pancreatic morphology and amylase release in vitro. | Pancreatic morphology and amylase release from isolated pancreatic acini in response to caerulein was studied in the course of an experimental bile induced acute pancreatitis without acinar necrosis. The inflammation was induced by retrograde microinfusion of 25 microliters bile into the rat bile pancreatic duct. A dis... | ['Amylases', 'Animals', 'Bile', 'Ceruletide', 'Disease Models, Animal', 'Edema', 'Female', 'In Vitro Techniques', 'Pancreas', 'Pancreatitis', 'Rats', 'Rats, Wistar', 'Time Factors'] | 7,523,259 | [['D08.811.277.450.066'], ['B01.050'], ['A12.200.087'], ['D12.644.456.241'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.888.277'], ['E05.481'], ['A03.734'], ['C06.689.750'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Elevated serum-soluble interleukin-2 receptor levels in patients with anaplastic large cell lymphoma. | Levels of serum soluble interleukin 2 receptor (sIL-2R) provide a reliable marker of disease activity in patients with hairy cell leukemia and adult T-cell leukemia/lymphoma. The malignant cells in patients with anaplastic large cell lymphoma (ALCL) express CD30 and are usually positive for expression of CD25. We measu... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Biomarkers, Tumor', 'Cyclophosphamide', 'Doxorubicin', 'Etoposide', 'Female', 'Humans', 'Ki-1 Antigen', 'Lymphoma, Large B-Cell, Diffuse', 'Male', 'Middle Aged', 'Prednisone', 'Receptors, Interleukin-2', 'Recurrence', 'Solubility', 'Vincristine'] | 15,205,267 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D23.101.140'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['D02.455.426.559.847.638.960.675.250', 'D04.615.638.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The use of the carbon dioxide laser in the management of condyloma acuminatum with eight-year follow-up. | This paper relates our comprehensive treatment and follow-up of 242 women with condyloma acuminatum over an 8-year period. Laser treatments were carried out at an average power density of 800 W/cm2. Thirty-five patients received a general anesthetic prior to treatment. All other patients were treated in the outpatient ... | ['Adolescent', 'Adult', 'Aged', 'Carbon Dioxide', 'Child', 'Child, Preschool', 'Colposcopy', 'Condylomata Acuminata', 'Female', 'Fever', 'Follow-Up Studies', 'Genital Neoplasms, Female', 'Glucocorticoids', 'Humans', 'Infant', 'Laser Therapy', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Penile Neoplasms', 'Pos... | 6,414,305 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.378.150', 'E01.370.388.250.150', 'E04.502.250.150', 'E04.520.150', 'E04.950.300.210'], ['C01.221.812.640.220', 'C01.778.640.220', 'C01.925.256.650.810.217', 'C01.925... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ebola and Localized Blame on Social Media: Analysis of Twitter and Facebook Conversations During the 2014-2015 Ebola Epidemic. | This study aimed to analyze main groups accused on social media of causing or spreading the 2014-2016 Ebola epidemic in West Africa. In this analysis, blame is construed as a vehicle of meaning through which the lay public makes sense of an epidemic, and through which certain classes of people become "figures of blame"... | ['Communication', 'Epidemics', 'Health Knowledge, Attitudes, Practice', 'Hemorrhagic Fever, Ebola', 'Humans', 'Qualitative Research', 'Social Media'] | 31,214,902 | [['F01.145.209', 'L01.143'], ['N06.850.290.200'], ['F01.100.150.500', 'N05.300.150.410'], ['C01.925.782.417.415', 'C01.925.782.580.250.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644.241.850'], ['L01.178.751', 'L01.224.230.110.500.750']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Significance of sympathetic innervation of pulmonary vessels in response to acute hypoxia. | The role of the autonomic nervous system on the pulmonary vascular response to hypoxia was studied in anesthetized open-chest dogs. Acute hypoxia elicited reversible decreases in the slope of the instantaneous diameter-pressure relationship of the main pulmonary artery. These decrements in vascular compliance during hy... | ['Animals', 'Dogs', 'Hypoxia', 'Pulmonary Artery', 'Sympathectomy', 'Sympathetic Nervous System', 'Vascular Resistance'] | 893,268 | [['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['C23.888.852.079'], ['A07.015.114.715'], ['E04.525.210.105.800'], ['A08.800.050.800'], ['G09.330.380.921']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Severe autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy in an adolescent girl with a novel AIRE mutation: response to immunosuppressive therapy. | Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a rare autosomal recessive disorder for which the gene (AIRE) has recently been identified on chromosome 21q22.3. We present the mutational analyses of a French-Canadian family with APECED, in which there are two affected siblings, as well as th... | ['Adolescent', 'Cyclosporine', 'DNA Mutational Analysis', 'Female', 'Humans', 'Immunosuppressive Agents', 'Magnesium', 'Male', 'Mutation', 'Pedigree', 'Polyendocrinopathies, Autoimmune', 'Transcription Factors', 'Treatment Outcome', 'Uric Acid'] | 10,084,559 | [['M01.060.057'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['E05.393.760.700.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['G05.365.590'], ['E05.393.673'], ['C19.787', 'C20.111.750'], ['D12.776.930'], ['E01.789.800', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cytoprotective effects of 5 benzophenones and a xanthone from Hypericum annulatum in models of epirubicin-induced cytotoxicity: SAR-analysis and mechanistic investigations. | A new benzophenone O-glucoside neoannulatophenonoside (1) together with the known pinocembrin-7-O-glucoside were isolated from the aerial parts of Hyperium annulatum Moris (Guttiferae). The former was identified as 3',5',6-trihydroxy-4-methoxybenzophenone-2-O-beta-D-glucopyranoside by means of chemical and physical evi... | ['Animals', 'Benzophenones', 'Cell Survival', 'Colony-Forming Units Assay', 'Cytoprotection', 'Epirubicin', 'Free Radical Scavengers', 'Granulocyte-Macrophage Colony-Stimulating Factor', 'Humans', 'Hypericum', 'K562 Cells', 'Mice', 'Molecular Structure', 'Myeloid Progenitor Cells', 'Plant Components, Aerial', 'Recombin... | 16,848,749 | [['B01.050'], ['D02.455.426.559.389.134', 'D02.522.223'], ['G04.346'], ['E01.370.225.500.383', 'E05.200.500.383', 'E05.242.383'], ['G07.690.773.500'], ['D02.455.426.559.847.562.050.200.175.200', 'D04.615.562.050.200.175.200', 'D09.408.051.059.200.175.200'], ['D27.505.519.217.500'], ['D12.644.276.374.410.240.375', 'D12.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Psychophysical evidence for an extrastriate contribution to a pattern-selective motion aftereffect. | A stationary vertical test grating appears to drift to the left after adaptation to an inducing grating drifting to the right, this being known as the motion aftereffect (MAE). Pattern-specific motion aftereffects (PSMAEs) induced by superimposed pairs of gratings in which the component gratings drift up and down but t... | ['Figural Aftereffect', 'Form Perception', 'Humans', 'Motion Perception', 'Optical Illusions', 'Orientation', 'Pattern Recognition, Visual', 'Psychophysics', 'Visual Cortex', 'Visual Pathways'] | 3,205,673 | [['F02.463.593.932.401', 'G14.360'], ['F02.463.593.373', 'F02.463.593.778.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.932.567'], ['F02.463.593.446.659'], ['F01.058.577', 'F02.830.606'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E01.370.685', 'F04.096.753'], ['A08.186.211.200.885.287.50... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ethnic and regional differences in prevalence and correlates of chronic diseases and risk factors in northern Canada. | INTRODUCTION: We investigated ethnic and geographic variations in major chronic diseases and risk factors in northern Canada, an area that is undergoing rapid changes in its social, cultural, and physical environments.METHODS: Self-report data were obtained from the population-based Canadian Community Health Survey in ... | ['Adult', 'Aged', 'American Native Continental Ancestry Group', 'Canada', 'Chronic Disease', 'Cross-Sectional Studies', 'Diabetes Mellitus', 'Ethnic Groups', 'Heart Diseases', 'Humans', 'Middle Aged', 'Obesity', 'Prevalence', 'Risk Factors', 'Smoking', 'Young Adult'] | 20,040,228 | [['M01.060.116'], ['M01.060.116.100'], ['M01.686.508.150'], ['Z01.107.567.176'], ['C23.550.291.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C18.452.394.750', 'C19.246'], ['M01.686.754', 'N01.224.317'], ['C14.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Overweight and Obesity in Midlife and Brain Structure and Dementia 26 Years Later: The AGES-Reykjavik Study. | High adiposity in midlife might increase risk for late-life brain pathology, including dementia. Using data from the prospective Age, Gene/Environment Susceptibility-Reykjavik Study of men and women (born 1907-1935), we studied the associations of overweight and obesity at midlife (mean age, 50 (standard deviation, 4.7... | ['Aged', 'Aged, 80 and over', 'Body Mass Index', 'Brain', 'Brain Infarction', 'Cerebral Hemorrhage', 'Dementia', 'Female', 'Follow-Up Studies', 'Humans', 'Iceland', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Obesity'] | 25,810,457 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['A08.186.211'], ['C10.228.140.300.150.477', 'C10.228.140.300.775.200', 'C14.907.253.092.477', 'C14.907.253.855.200', 'C23.550.513.355.250', 'C23.550.717.489.250'], ['C10.228.140.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Prey body mass and richness underlie the persistence of a top predator. | Predators and prey often differ in body mass. The ratio of predator to prey body mass influences the predator's functional response (how consumption varies with prey density), and therefore, the strength and stability of the predator-prey interaction. The persistence of food chains is maximized when prey species are ne... | ['Animals', 'Body Size', 'Coleoptera', 'Diptera', 'Food Chain', 'Insecta', 'Models, Biological', 'Odonata', 'Oligochaeta', 'Predatory Behavior'] | 31,064,301 | [['B01.050'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['B01.050.500.131.617.720.500.500.375'], ['B01.050.500.131.617.720.500.500.750'], ['G16.500.275.157.250', 'N06.230.124.250'], ['B01.050.500.131.617'], ['E05.599.395'], ['B01.050.500.131.617.720.750.750'], ['B01.050.500.0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A two-stage approach to the joint analysis of longitudinal and survival data utilising the Coxian phase-type distribution. | The Coxian phase-type distribution is a special type of Markov model which can be utilised both to uncover underlying stages of a survival process and to make inferences regarding the rates of flow of individuals through these latent stages before an event of interest occurs. Such models can be utilised, for example, t... | ['Biomarkers', 'Hemoglobins', 'Humans', 'Kidney Failure, Chronic', 'Linear Models', 'Longitudinal Studies', 'Markov Chains', 'Survival Analysis'] | 28,633,604 | [['D23.101'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.8... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Elevated cerebrospinal fluid level of ciliary neurotrophic factor in acute disseminated encephalomyelitis. | We investigated the concentrations of ciliary neurotrophic factor (CNTF) in cerebrospinal fluid (CSF) from children with inflammatory diseases of the central nervous system. We studied 6 children with acute disseminated encephalomyelitis (ADEM), 14 with acute encephalitis/encephalopathy, 17 with bacterial meningitis, a... | ['Child', 'Child, Preschool', 'Encephalitis', 'Encephalomyelitis, Acute Disseminated', 'Female', 'Humans', 'Male', 'Meningitis, Aseptic', 'Meningitis, Bacterial'] | 10,980,311 | [['M01.060.406'], ['M01.060.406.448'], ['C10.228.140.430'], ['C10.114.375.225', 'C10.228.140.695.562.225', 'C10.314.350.225', 'C20.111.258.250.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.614.220'], ['C01.150.252.223.500', 'C01.207.180.500', 'C10.228.228.180.500', 'C10.228.614.280']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The cooperative effect of p53 and Rb in local nanotherapy in a rabbit VX2 model of hepatocellular carcinoma. | BACKGROUND/AIM: A local nanotherapy (LNT) combining the therapeutic efficacy of trans-arterial embolization, nanoparticles, and p53 gene therapy has been previously presented. The study presented here aimed to further improve the incomplete tumor eradication and limited survival enhancement and to elucidate the molecul... | ['Animals', 'Carcinoma, Hepatocellular', 'Cell Line, Tumor', 'DNA', 'Female', 'Genetic Therapy', 'Male', 'Nanocapsules', 'Rabbits', 'Retinoblastoma Protein', 'Transfection', 'Treatment Outcome', 'Tumor Suppressor Protein p53'] | 24,124,364 | [['B01.050'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A11.251.210.190', 'A11.251.860.180'], ['D13.444.308'], ['E02.095.301', 'E05.393.420.301'], ['D26.255.260.575', 'E02.319.300.380.575', 'J01.637.512.600.575'], ['B01.050.150.900.649.313.968.700'], ['D12.776.260.704',... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse model. | Ovarian cancer is the leading cause of cancer related deaths in women. Genetic alterations including overexpression of EGFR play a crucial role in ovarian carcinogenesis. Here we evaluated the effect of phenethyl isothiocyanate (PEITC) in ovarian tumor cells in vitro and in vivo. Oral administration of 12 µmol PEITC re... | ['Animals', 'Annexin A5', 'Antineoplastic Agents', 'Apoptosis', 'Cell Line, Tumor', 'Drug Screening Assays, Antitumor', 'ErbB Receptors', 'Female', 'Humans', 'Isothiocyanates', 'Mice', 'Mice, Nude', 'Neoplasm Transplantation', 'Ovarian Neoplasms', 'Proto-Oncogene Proteins c-akt', 'Rhodamines'] | 22,952,709 | [['B01.050'], ['D12.776.157.125.050.100'], ['D27.505.954.248'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['B01.050.150.900.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recombinant truncated AniA of pathogenic Neisseria elicits a non-native immune response and functional blocking antibodies. | AniA of the pathogenic Neisseria is glycosylated in its C-terminal repeat region by the pilin glycosylation (pgl) pathway. AniA appears to be unique among bacterial nitrite reductases as it contains an N-terminal extension that includes a lipid modification site as well as a C-terminal extension that is glycosylated. I... | ['Antibodies, Blocking', 'Antigens, Bacterial', 'Bacterial Outer Membrane Proteins', 'Bacterial Vaccines', 'Glycosylation', 'Neisseria gonorrhoeae', 'Nitrite Reductases', 'Recombinant Proteins'] | 23,313,483 | [['D12.776.124.486.485.114.143', 'D12.776.124.790.651.114.143', 'D12.776.377.715.548.114.143'], ['D23.050.161'], ['D12.776.097.120', 'D12.776.543.100'], ['D20.215.894.135'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['B03.440.400.425.550.550.474', 'B03.660.075.525.520.400'], ['D08.811.682.655.750'], ['D12.776.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Long-Term Efficacy of a Galactagogue Containing Sylimarin-Phosphatidylserine and Galega on Milk Production of Mothers of Preterm Infants. | AIMS: To investigate the efficacy of a galactagogue, containing Sylimarin-phosphatidylserine (SILITIDIL) and galega consumed in the first month after delivery by mothers of preterm infants, in maintaining milk production during the first 3-6 months after delivery.MATERIALS AND METHODS: Mothers of infants born at gestat... | ['Breast Feeding', 'Double-Blind Method', 'Female', 'Galactogogues', 'Galega', 'Gestational Age', 'Humans', 'Infant', 'Infant, Newborn', 'Infant, Premature', 'Italy', 'Lactation', 'Milk, Human', 'Phosphatidylserines', 'Prospective Studies', 'Silymarin', 'Time Factors'] | 29,148,822 | [['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D27.505.696.365'], ['B01.650.940.800.575.912.250.401.250'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Development and evaluation of a latex agglutination test for the rapid serodiagnosis of tularemia. | A latex agglutination test (LAT) was developed for a rapid detection of antibodies against Francisella tularensis. The assay is performed by mixing serum with antigen-coated latex beads and read within 5 min. Developed LAT has been proved to be a specific, sensitive, fast, easy-to-perform and cost-efficient tool for th... | ['Antibodies, Bacterial', 'Costs and Cost Analysis', 'Francisella tularensis', 'Humans', 'Latex Fixation Tests', 'Sensitivity and Specificity', 'Serologic Tests', 'Tularemia'] | 25,727,796 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['N03.219.151'], ['B03.440.400.425.340.590', 'B03.660.250.200.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.735.050.450', 'E05.200.812.735.050.450', 'E05.478.594.760.050.450'], ['E05.318.370.800',... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[An enzootic with pseudo-tumoral manifestations in Vipera lebetina in captivity]. | The authors report the clinical and epizootic evolution of an epizooty, characterized by pseudo-tumours, observed on some vipers (Vipera lebetina) maintained in captivity at the "institut Pasteur de Tunis". The disease was characterized by 2.3 cm size nodules, scattered under the skin or into splanchnic cavities. These... | ['Animals', 'Female', 'Fibroma', 'Infections', 'Male', 'Snakes'] | 747,451 | [['B01.050'], ['C04.557.450.565.590.340'], ['C01'], ['B01.050.150.900.833.672']] | ['Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An exploratory retrospective evaluation of ropinirole-associated psychotic symptoms in an outpatient population treated for restless legs syndrome or Parkinson's disease. | BACKGROUND: Traditional treatment approaches for the management of restless legs syndrome (RLS) and Parkinson's disease (PD) include the use of medications that either directly or indirectly increase dopamine levels. In turn, a potential adverse event that could be expected is the development or exacerbation of psychia... | ['Aged', 'Aged, 80 and over', 'Databases, Factual', 'Dopamine Agonists', 'Female', 'Humans', 'Indoles', 'Male', 'Middle Aged', 'Outpatients', 'Parkinson Disease', 'Psychoses, Substance-Induced', 'Restless Legs Syndrome', 'Retrospective Studies', 'Risk Factors'] | 19,690,226 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['D27.505.519.625.150.151', 'D27.505.696.577.150.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473'], ['M01.060.116.630'], ['M01.643.630'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.5... | ['Named Groups [M]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Phytochrome A enhances the promotion of hypocotyl growth caused by reductions in levels of phytochrome B in its far-red-light-absorbing form in light-grown Arabidopsis thaliana. | We sought to determine if phytochrome B (phyB)-mediated responses to the red light (R)/far-red light (FR) ratio are affected by phytochrome A (phyA) activity in light-grown seedlings of Arabidopsis thaliana. Pulses of FR delayed into the dark period were less effective than end-of-day (EOD) FR in promoting hypocotyl gr... | ['Arabidopsis', 'Arabidopsis Proteins', 'Cucumis sativus', 'Darkness', 'Genes, Plant', 'Hypocotyl', 'Light', 'Lighting', 'Lycopersicon esculentum', 'Mustard Plant', 'Photoreceptor Cells', 'Phytochrome', 'Phytochrome A', 'Phytochrome B', 'Plants, Medicinal', 'Plants, Toxic', 'Tobacco', 'Transcription Factors'] | 8,938,405 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['B01.650.940.800.575.912.250.300.188.666'], ['G01.590.540.233'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['A18.024.875.750', 'A18.024.937.249', 'A18.550.500'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['N06.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Practical electron dosimetry. A comparison of different types of ionization chambers]. | Since Markus chambers are no longer recommended in the 1997 DIN 6800-2 version there are uncertainties as to the use of alternative chamber types for electron dosimetry. Therefore, we performed a comparison between different types of ionization chambers. In particular, the widespread Farmer and Roos chambers were compa... | ['Electrons', 'Protons', 'Radiometry'] | 12,001,368 | [['G01.249.335', 'G01.358.500.750'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['E05.799']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Expression of cytokine-induced apoptosis inhibitor 1 in gastric cancer tissues and its effects on invasion and migration of SGC-7901 cell]. | OBJECTIVE: To examine the expression of cytokine-induced apoptosis inhibitor1 (CIAPIN1) in gastric cancer and normal mucosa tissues, and to investigate its effects on migration and invasion of gastric cancer cells.METHODS: Immunohistochemistry was used to detect CIAPIN1 expression in 15 samples of normal gastric mucosa... | ['Cell Line, Tumor', 'Down-Regulation', 'Humans', 'Immunohistochemistry', 'Intracellular Signaling Peptides and Proteins', 'Lymphatic Metastasis', 'Neoplasm Staging', 'Stomach Neoplasms', 'Up-Regulation'] | 26,404,695 | [['A11.251.210.190', 'A11.251.860.180'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Mismatch negativity (MMN) in multiple sclerosis: an event-related potentials study in 46 patients. | OBJECTIVE: To assess pre-attentive detection mechanisms indexed by MMN component of auditory Event-Related Potentials (ERPs) in Multiple Sclerosis (MS) patients.METHODS: 46 MS patients (mean age 43.7 years, mean disease duration 10.1 years, mean EDSS 4.6) and 46 matched controls were assessed with ERPs elicited by a pa... | ['Acoustic Stimulation', 'Adult', 'Case-Control Studies', 'Chi-Square Distribution', 'Cognition Disorders', 'Contingent Negative Variation', 'Electroencephalography', 'Evoked Potentials', 'Female', 'Humans', 'Male', 'Middle Aged', 'Multiple Sclerosis', 'Neuropsychological Tests', 'Psychometrics', 'Reaction Time'] | 16,325,469 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['F03.615.250'], ['G07.265.216.500.250', 'G11.561.200.500.250'], ['E01.370.376.300... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Structure and kinetics of a transient antibody binding intermediate reveal a kinetic discrimination mechanism in antigen recognition. | Induced fit is a predominant phenomenon in protein-ligand interactions, yet it is invariably attributed without establishing the existence, let alone the structure, of the initial, low-affinity encounter complex. We determined the crystal structure of the encounter complex on the pathway of ligand binding by IgE antibo... | ['Anthracenes', 'Antibody Specificity', 'Antigens', 'Binding Sites', 'Crystallography, X-Ray', 'Hydrogen Bonding', 'Immunoglobulin E', 'Isomerism', 'Kinetics', 'Ligands', 'Models, Molecular', 'Protein Binding', 'Protein Structure, Quaternary'] | 16,129,832 | [['D02.455.426.559.847.117', 'D04.615.117'], ['G12.100'], ['D23.050'], ['G02.111.570.120'], ['E05.196.309.742.225'], ['G02.282'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.377.715.548.114.619.312'], ['G02.111.570.685', 'G02.607.445'], ['G01.374.661', 'G02.111.490'], ['D27.720.470.4... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of PS1 1/2, ACE I/D, and LRP C/T polymorphisms with Alzheimer's disease in the Chinese population: a meta-analysis of case-control studies. | The objective of this study was to assess the associations of presenilin 1 (PS1) 1/2, angiotensin I-converting enzyme (ACE) insertion/deletion (I/D), and low-density lipoprotein receptor-related protein (LRP) C/T polymorphisms with the risk of Alzheimer's disease (AD) in the Chinese population. PS1 1/2, ACE I/D, and LR... | ['Aged', 'Aged, 80 and over', 'Alleles', 'Alzheimer Disease', 'Asian Continental Ancestry Group', 'China', 'Female', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Humans', 'INDEL Mutation', 'Low Density Lipoprotein Receptor-Related Protein-1', 'Peptidyl-Dipeptidase A', 'Polymorphism, Single Nucle... | 25,730,041 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G05.360.340.024.340.030'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['M01.686.508.200'], ['Z01.252.474.164'], ['E05.393.385'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590.500', 'G05.558.370'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Endurance testing for evaluation of antianginal therapy with amlodipine, a calcium channel blocking agent. | The utility of using an endurance test as well as a maximal exercise test to assess the effect of amlodipine, a dihydropyridine calcium antagonist, was evaluated in 16 patients with angina pectoris. Amlodipine, 10 mg/day, was compared with placebo in a double blind crossover study. After a 2 week single blind placebo p... | ['Aged', 'Amlodipine', 'Angina Pectoris', 'Calcium Channel Blockers', 'Double-Blind Method', 'Evaluation Studies as Topic', 'Exercise Test', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nifedipine', 'Oxygen Consumption', 'Physical Endurance'] | 2,969,930 | [['M01.060.116.100'], ['D03.383.725.203.065'], ['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E05.337', 'N05.715.360.335'], ['E01.370.370.380... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Pilocarpine-induced seizures cause selective time-dependent changes to adult-generated hippocampal dentate granule cells. | Aberrantly interconnected granule cells are characteristic of temporal lobe epilepsy. By reducing network stability, these abnormal neurons may contribute directly to disease development. Only subsets of granule cells, however, exhibit abnormalities. Why this is the case is not known. Ongoing neurogenesis in the adult ... | ['Animals', 'Axons', 'Cell Death', 'Cell Division', 'Cell Movement', 'Cellular Senescence', 'Dendrites', 'Dentate Gyrus', 'Epilepsy', 'Female', 'Green Fluorescent Proteins', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Mossy Fibers, Hippocampal', 'Neurons', 'Pilocarpine', 'Status Epilepticus', 'Time Facto... | 17,626,215 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['G04.146'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.198', 'G07.568.500.180'], ['G04.043'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['A08.186.211.180.405.200', 'A08.186.211.200.885.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Congenital adrenal hyperplasia in females with virilized genitalia: the problem of delayed diagnosis. | Six girls with the non-salt-losing form of congenital adrenal hyperplasia are described. Diagnosis was delayed in five, the range of ages of diagnosis being 19 months-7 years. In the sixth, despite early diagnosis and medical treatment, surgery was delayed electively until she was 3 years old. The five in whom diagnosi... | ['Adrenal Hyperplasia, Congenital', 'Biomarkers', 'Child', 'Child, Preschool', 'Female', 'Genitalia, Female', 'Humans', 'Infant', 'Steroid Hydroxylases', 'Virilism'] | 3,265,322 | [['C12.706.316.090.500', 'C13.351.875.253.090.500', 'C16.131.939.316.129.500', 'C16.320.033', 'C16.320.565.925.249', 'C18.452.648.925.249', 'C19.053.440', 'C19.391.119.090.500'], ['D23.101'], ['M01.060.406'], ['M01.060.406.448'], ['A05.360.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D08.2... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Expression specificity of hpt gene in sck transgenic rice]. | OBJECTIVE: Evaluate the expression specificity of hpt gene in different developmental stages of sck transgenic rice.METHODS: The different tissues, including leaves, culms, roots and seeds (ripening stage), in different developmental stages of sck transgenic rice were detected by PCR. The positive plants and the contro... | ['Gene Expression Regulation, Plant', 'Genetic Markers', 'Oryza', 'Phosphotransferases (Alcohol Group Acceptor)', 'Plants, Genetically Modified', 'Seeds'] | 16,229,277 | [['G05.308.375'], ['D23.101.387', 'G05.695.450'], ['B01.650.940.800.575.912.250.822.616'], ['D08.811.913.696.620'], ['B01.650.520', 'B05.620.600'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Use of eating-pattern messages to evaluate changes in eating behaviors in a worksite cholesterol education program. | OBJECTIVE: To determine whether eating-pattern messages can effectively be used in a worksite cholesterol education program to change eating behaviors.SUBJECTS: 91 randomly selected participants with initial serum cholesterol levels of 5.2 mmol/L attended the program.INTERVENTION: Eating-pattern messages were the focus... | ['Arizona', 'Cholesterol', 'Cholesterol, Dietary', 'Dietary Fats', 'Dietary Services', 'Feeding Behavior', 'Health Education', 'Humans', 'Nutritional Sciences', 'Occupational Health Services', 'Regression Analysis', 'Surveys and Questionnaires'] | 8,409,132 | [['Z01.107.567.875.760.100'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.225', 'D10.212.302.347', 'D10.570.938.208.222'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['N02.421.242'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['I02.233.332', '... | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and... | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
[New trends in extracorporeal shockwave lithotripsy]. | Extracorporeal shock wave lithotripsy has become an established and successful treatment modality for urinary and biliary calculi. However, shock wave technology and corresponding device designs are still at an innovative stage. Three trends are discussed in this paper. In shock wave technology the electromagnetic prin... | ['Equipment Design', 'Humans', 'Lithotripsy'] | 1,571,373 | [['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.600', 'E04.943.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Functional kaolin supported nanoscale zero-valent iron as a Fenton-like catalyst for the degradation of Direct Black G. | Kaolin supported nanoscale zero-valent iron (K-nZVI) is synthesized and applied as the Fenton-like oxidation catalyst to degrade a model azo dye, Direct Black G (DBG). The characterization of K-nZVI by the high resolution transmission electronmicroscopy (HRTEM), X-ray photoelectron spectroscopy (XPS), scanning electron... | ['Adsorption', 'Catalysis', 'Coloring Agents', 'Iron', 'Kaolin', 'Kinetics', 'Microscopy, Electron, Scanning', 'Photoelectron Spectroscopy', 'Waste Disposal, Fluid', 'Waste Water', 'Water Pollutants, Chemical', 'X-Ray Diffraction'] | 28,628,903 | [['G01.030', 'G02.020'], ['G02.130'], ['D27.720.233'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D01.056.050.075.350', 'D01.578.725.025.350', 'D01.650.550.050.075.350', 'D01.837.725.700.760.050.400'], ['G01.374.661', 'G02.111.490'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E05.196.867.618'],... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Lupus erythematosus latex tests compared with the immunofluorescence method for antinuclear factor. | Two commercially available lupus erythematosus (LE) latex tests were compared against positive antinuclear antibody (ANF) sera of known titers. The Lederle SLE Latex Test Kit was found to be more specific and relatively more sensitive, particulary with high ANF titers, than the Hyland LE Test Kit. The latex test is a r... | ['Antibodies, Antinuclear', 'Deoxyribonucleoproteins', 'Fluorescent Antibody Technique', 'Humans', 'Latex Fixation Tests', 'Lupus Erythematosus, Systemic', 'Staining and Labeling'] | 58,558 | [['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['D12.776.664.275'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Autologous blood donation and transfusion in Europe. | BACKGROUND AND OBJECTIVES: The aim of this study was to record practices in autologous blood transfusion in Europe in 1997.MATERIALS AND METHODS: A questionnaire mainly about predeposit was distributed to the National Representatives of all 41 member states of the Council of Europe's Committee of Experts on Blood Trans... | ['Blood Banks', 'Blood Donors', 'Blood Preservation', 'Blood Transfusion, Autologous', 'Europe', 'Humans', 'Mass Screening', 'Practice Guidelines as Topic', 'Surveys and Questionnaires'] | 11,555,472 | [['N02.278.065.200'], ['M01.898.313'], ['E02.792.833.230', 'E05.760.833.230'], ['E02.095.135.164'], ['Z01.542'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.780.500'], ['N04.761.... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Spatial distribution of light and nutrients in some coral reefs of Costa Rica during January 1997. | The proximity of coral reefs to areas of present and future coastal development in Costa Rica highlights the need for assessing environmental conditions important to maintaining healthy corals. In January 1997 a survey of light penetration, inorganic nutrient concentrations, temperature, and salinity was conducted in t... | ['Animals', 'Anthozoa', 'Costa Rica', 'Light', 'Organic Chemicals', 'Seawater', 'Sodium Chloride', 'Temperature'] | 15,264,539 | [['B01.050'], ['B01.050.500.308.237'], ['Z01.107.169.238'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D02'], ['G16.500.275.725.500'], ['D01.210.450.150.875', 'D01.857.650'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.71... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[Possibilities and limits of reconstructive surgery of the recurrent laryngeal nerve]. | The authors report on possibilities and borderlines of reconstructive microsurgery of the recurrent laryngeal nerve. When paralysis of the vocal cord is proved after thyreoidectomy exploration and control of the nerve should be done immediately. This must be done as fast as possible, latest at the 7th day after thyreoi... | ['Follow-Up Studies', 'Humans', 'Microsurgery', 'Postoperative Complications', 'Recurrent Laryngeal Nerve', 'Recurrent Laryngeal Nerve Injuries', 'Reoperation', 'Suture Techniques', 'Thyroidectomy', 'Vocal Cord Paralysis'] | 1,543,520 | [['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.494', 'E05.591.580'], ['C23.550.767'], ['A08.800.050.050.925.450.700', 'A08.800.050.600.825.450.700', 'A08.800.800.060.920.450.700', 'A08.800.800.120.900.450.700'], ['C08.36... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Long-term suppression of telomerase expression in HeLa cell clones, transfected with an expression vector carrying siRNA targeting hTERT mRNA. | HeLa cell cultures were used as model systems for small interfering RNA (siRNA) induced knockdown of mRNA expression of the human telomerase catalytic subunit, telomerase reverse transcriptase (hTERT). Four 21-bp siRNAs targeting different sites of the hTERT mRNA were designed, and the siRNA molecules produced by a T7 ... | ['Apoptosis', 'Cell Proliferation', 'Cell Shape', 'Clone Cells', 'Female', 'Gene Expression Regulation, Neoplastic', 'Genetic Vectors', 'HeLa Cells', 'Humans', 'RNA Interference', 'RNA, Messenger', 'RNA, Small Interfering', 'Telomerase', 'Telomere', 'Time Factors', 'Transfection', 'Uterine Cervical Neoplasms'] | 16,773,210 | [['G04.146.954.035'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.320'], ['A11.251.353'], ['G05.308.370'], ['G05.360.337'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.308.203.374.790'], ['D13.444.735.544'], ['D13.150.650.700', 'D13.444.735.150... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term observations of cardiac arrhythmias during and after cardiac surgery. I. Acquired heart disease. | Twelve arrhythmias that occurred during and following surgery for acquired heart disease were studied in a group of 52 randomly selected patients. In cases of aortic and mitral valve replacement, Bj?rk-Shiley prosthetic valves were used, and procain-magnesium-aspartate solution was applied for cardiac arrest. Registrat... | ['Adult', 'Aortic Valve', 'Arrhythmias, Cardiac', 'Cardiopulmonary Bypass', 'Extracorporeal Circulation', 'Female', 'Follow-Up Studies', 'Heart Arrest, Induced', 'Heart Valve Diseases', 'Heart Valve Prosthesis', 'Humans', 'Male', 'Middle Aged', 'Mitral Valve', 'Postoperative Complications', 'Time Factors'] | 1,273,557 | [['M01.060.116'], ['A07.541.510.110'], ['C14.280.067', 'C23.550.073'], ['E04.292.413'], ['E04.292'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.100.376.374', 'E04.928.220.360'], ['C14.280.484'], ['E07.695.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Negotiating the Space Between Openness and Rejection - Mental Health Nurses' Attitudes Towards Risk Behaviour of their Patients - A Qualitative Study]. | Objective Personal recovery as a key concept in mental health requests that people with severe mental illness need support in taking positive risks, especially from mental health nurses as key players in this context. In German-speaking countries, studies regarding positive risk-taking seem scarce. Attitude as a concep... | ['Adaptation, Psychological', 'Adult', 'Attitude of Health Personnel', 'Female', 'Focus Groups', 'Germany', 'Guideline Adherence', 'Hospitals, Psychiatric', 'Humans', 'Male', 'Middle Aged', 'Negotiating', 'Nurse-Patient Relations', 'Outpatient Clinics, Hospital', 'Psychiatric Nursing', 'Qualitative Research', 'Rejectio... | 27,618,170 | [['F01.058'], ['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['Z01.542.315'], ['N04.761.337', 'N05.715.360.395'], ['N02.278.421.556.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.145.209.520', 'F01.829.401.520', 'F0... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Functional role of inward rectifier current in heart probed by Kir2.1 overexpression and dominant-negative suppression. | The inward rectifier current I(K1) is tightly regulated regionally within the heart, downregulated in heart failure, and genetically suppressed in Andersen syndrome. We used in vivo viral gene transfer to dissect the role of I(K1) in cardiac repolarization and maintenance of the resting membrane potential (RMP) in guin... | ['Action Potentials', 'Adenoviridae', 'Animals', 'Cell Line', 'Cell Separation', 'Electrocardiography', 'Female', 'Gene Transfer Techniques', 'Genes, Dominant', 'Guinea Pigs', 'Heart', 'Humans', 'Mutation', 'Myocardium', 'Myocytes, Cardiac', 'Patch-Clamp Techniques', 'Phenotype', 'Potassium Channels, Inwardly Rectifyin... | 12,750,402 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B04.280.030'], ['B01.050'], ['A11.251.210'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.393.350'], ['G05.360.340.024.340.240', 'G05.420.320'], ['B01.050.150.900.649.313.992.550'], ['A07.541'], ['B... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Functional implications for the microtubule-associated protein tau: localization in oligodendrocytes. | We present evidence that the microtubule-associated protein tau is present in oligodendrocytes (OLGs), the central nervous system cells that make myelin. By showing that tau is distributed in a pattern similar to that of myelin basic protein, our results suggest a possible involvement of tau in some aspect of myelinati... | ['Animals', 'Blotting, Western', 'Brain', 'Cells, Cultured', 'Electrophoresis, Polyacrylamide Gel', 'Fluorescent Antibody Technique, Indirect', 'Immunohistochemistry', 'In Situ Hybridization, Fluorescence', 'Microscopy, Immunoelectron', 'Myelin Basic Protein', 'Oligodendroglia', 'Rats', 'Sheep', 'tau Proteins'] | 7,479,786 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A08.186.211'], ['A11.251'], ['E05.196.401.402', 'E05.301.300.319'], ['E01.370.225.500.607.512.240.310', 'E01.370.225.750.551.512.240.310', 'E05.200.500.607.512.240.310', 'E05.200.750.551.512.240.310', 'E... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Mapping of the antibody-binding regions on the HN-domain (residues 449-859) of botulinum neurotoxin A with antitoxin antibodies from four host species. Full profile of the continuous antigenic regions of the H-chain of botulinum neurotoxin A. | Previously, we mapped the antibody (Ab) and T-cell recognition regions on the HC domain (residues 855-1296) of the 848-residue heavy (H) chain of botulinum neurotoxin A (BoNT/A). We have mapped here the HN-domain (residues 449-859) regions that bind protective anti-BoNT/A Abs raised in four different species. We synthe... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Bacterial', 'Antibody Specificity', 'Bacterial Vaccines', 'Botulinum Toxins, Type A', 'Chickens', 'Clostridium botulinum', 'Epitope Mapping', 'Epitopes', 'Horses', 'Humans', 'Mice', 'Molecular Sequence Data', 'Neuromuscular Agents', 'Peptides', 'Protein Structure, Tertiar... | 15,115,181 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['G12.100'], ['D20.215.894.135'], ['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['B01.050.150.9... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Long-chain non-coding RNA MALAT1 regulates paclitaxel resistance of breast cancer cells by targeting miR-485-3p]. | OBJECTIVE: To investigate the role of long-chain non-coding RNA MALAT1 in modulating paclitaxel resistance in breast cancer cells.METHODS: Breast cancer SK-BR-3 cells were treated with gradient concentrations of paclitaxel to induce paclitaxel resistance of the cells. The resistant cells were transfected with si-NC, si... | ['Cell Line, Tumor', 'Humans', 'MicroRNAs', 'Paclitaxel', 'RNA, Long Noncoding'] | 32,897,218 | [['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['D02.455.426.392.368.242.888.777', 'D02.455.849.291.850.777'], ['D13.444.735.790.375']] | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ultrastructure, karyology and immunology of a cell line originated from a human transitional-cell carcinoma. | A cell line (J82) was derived from a poorly differentiated, invasive, transitional-cell carcinoma, Stage T3. The cells have been propagated in vitro for 5 years and showed 100% aneuploidy and a mixed epithelial-fibroblastic morphology. The majority of cells contained 2Y chromosomes and several distinctive markers. Peri... | ['Carcinoma, Transitional Cell', 'Cell Line', 'Chromosome Banding', 'Chromosomes', 'Culture Techniques', 'Cytoplasm', 'Cytotoxicity, Immunologic', 'Humans', 'Karyotyping', 'Lymphocytes', 'Microscopy, Electron'] | 687,519 | [['C04.557.470.200.430'], ['A11.251.210'], ['E01.370.225.500.385.130', 'E01.370.225.500.620.670.130', 'E01.370.225.750.600.670.130', 'E05.200.500.385.130', 'E05.200.500.620.670.130', 'E05.200.750.600.670.130', 'E05.242.385.130', 'E05.393.285.130'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['E05.48... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Trocar guided laparoscopic feeding jejunostomy: a simple new technique. | PURPOSE: Several techniques of laparoscopic feeding jejunostomy have been described. Most of them require costly commercial kits. Here we present a novel, simple, low-cost method for laparoscopic jejunostomy tube placement.METHODS: This technique involves 4 ports. A left lateral "guide" trocar is used as a landmark for... | ['Aged', 'Aged, 80 and over', 'Enteral Nutrition', 'Equipment Design', 'Female', 'Humans', 'Intubation, Gastrointestinal', 'Jejunostomy', 'Laparoscopy', 'Male', 'Malnutrition', 'Middle Aged', 'Retrospective Studies', 'Surgical Instruments'] | 23,047,399 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.421.360', 'E02.642.500.360'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.585.412', 'E05.497.412'], ['E04.210.338.523', 'E04.579.338.523'], ['E01.370.388.250.520', 'E04.502.250.520'], ['C18.654.521'], ['M01.060.116.630'], ['E05.318.372.500.500... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tailored education program using home floor plans for falls prevention in discharged older patients: A pilot randomized controlled trial. | OBJECTIVE: To investigate the effect of a tailored education program using home floor plans on falls prevention in discharged older patients.DESIGN: A single-center, parallel, pragmatic, pilot randomized controlled trial with equal allocation to the intervention and control groups.SETTING: Discharged hospital patients ... | ['Accidental Falls', 'Aged', 'Aged, 80 and over', 'Exercise Therapy', 'Female', 'Humans', 'Male', 'Patient Discharge', 'Patient Education as Topic', 'Pilot Projects'] | 28,242,580 | [['N06.850.135.122'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.169.125', 'E02.760.400.610', 'N02.421.585.169.125', 'N02.421.585.400.610', 'N04.590.233.727.210.125'], ['I02.233.332.500', 'N02.42... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Induction of mutation to streptomycin resistance in Micrococcus radiodurans. | No detectable induction of mutation to streptomycin resistance could be used in wild-type Micrococcus radiodurans and its radiation-sensitive and super-resistant mutants by ionizing or UV-radiation. N-methyl-N'-nito-N-nitrosoguanidine (NTG) was mutagenically active. The results suggest that repair of radiation-damaged ... | ['Cobalt Radioisotopes', 'DNA Repair', 'DNA, Bacterial', 'Drug Resistance, Microbial', 'Micrococcus', 'Mutagens', 'Mutation', 'Nitrosoguanidines', 'Radiation Genetics', 'Streptomycin', 'Ultraviolet Rays'] | 1,143,295 | [['D01.268.556.185.500.354', 'D01.268.956.155.500.354', 'D01.496.239.354', 'D01.496.749.256', 'D01.552.544.185.500.354'], ['G02.111.222', 'G05.219'], ['D13.444.308.212'], ['G06.225', 'G07.690.773.984.269'], ['B03.510.024.850.500', 'B03.510.400.500.500'], ['D27.888.569.468'], ['G05.365.590'], ['D02.078.370.649', 'D02.65... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Prediction of influenza B vaccine effectiveness from sequence data. | Influenza is a contagious respiratory illness that causes significant human morbidity and mortality, affecting 5-15% of the population in a typical epidemic season. Human influenza epidemics are caused by types A and B, with roughly 25% of human cases due to influenza B. Influenza B is a single-stranded RNA virus with ... | ['Antigens, Viral', 'Cluster Analysis', 'Epitope Mapping', 'Evolution, Molecular', 'Humans', 'Immunogenicity, Vaccine', 'Influenza B virus', 'Influenza Vaccines', 'Influenza, Human', 'RNA, Viral', 'Sequence Alignment'] | 27,473,305 | [['D23.050.327'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.478.274', 'E05.601.690.300'], ['G05.045.250', 'G16.075.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.513'], ['B04.820.480.968.407.410'], ['D20.215.894.899.302'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Maternal serum anti-D antibody concentration monitoring and transfusion practices in obstetrics in France: a preliminary study]. | OBJECTIVES: In obstetrics, transfusion medicine is involved because of the risk of Rh isoimmunisation and of transfusion at delivery. In France, although these two situations have led to legal or professional recommendations, practices appear to be very different from one institution or one physician to another.STUDY D... | ['Adult', 'Blood Cell Count', 'Blood Transfusion', 'Delivery, Obstetric', 'Female', 'France', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Isoantibodies', 'Pregnancy', 'Retrospective Studies', 'Rh-Hr Blood-Group System', 'Rho(D) Immune Globulin', 'Surveys and Questionnaires'] | 11,392,242 | [['M01.060.116'], ['E01.370.225.500.195.107', 'E01.370.225.625.107', 'E05.200.500.195.107', 'E05.200.625.107', 'E05.242.195.107', 'G04.140.107', 'G09.188.105'], ['E02.095.135'], ['E04.520.252'], ['Z01.542.286'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
High-dose chemotherapy followed by autologous stem cell transplantation as first-line therapy in aggressive non-Hodgkin's lymphoma: a meta-analysis. | BACKGROUND AND OBJECTIVES: High-dose chemotherapy followed by autologous stem cell transplantation (HDT/ASCT) has proven to be superior to conventional chemotherapy in patients with chemosensitive relapse of aggressive non-Hodgkin's lymphoma (NHL). Therefore, HDT/ASCT was evaluated as part of first-line therapy. Severa... | ['Adolescent', 'Adult', 'Antineoplastic Combined Chemotherapy Protocols', 'Combined Modality Therapy', 'Female', 'Humans', 'Lymphoma, Non-Hodgkin', 'Male', 'Middle Aged', 'Peripheral Blood Stem Cell Transplantation', 'Prospective Studies', 'Randomized Controlled Trials as Topic', 'Survival Analysis', 'Transplantation C... | 14,607,760 | [['M01.060.057'], ['M01.060.116'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480', 'C15.604.515.569.480', 'C20.683.515.761.480'], ['M01.060.116.630'], ['E02.095.147.500.500.500.500', 'E04.936.225.687.500.500'], ['E05.318.372.50... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Precursor B-1 B cell lymphoma in a newborn calf. | A newborn Holstein female calf had neoplastic lesions in the skin and within the thoracic and abdominal cavities but not in the bone marrow, spleen, thymus, or most lymph nodes. Because the tumor cells were positive for CD79a (B cell marker), CD5 (B-1 cell marker) and terminal deoxynucleotidyl transferase (marker for i... | ['Animals', 'Animals, Newborn', 'B-Lymphocyte Subsets', 'Cattle', 'Cattle Diseases', 'Female', 'Immunohistochemistry', 'Lymphoma, B-Cell', 'Mesentery', 'Skin'] | 17,609,362 | [['B01.050'], ['B01.050.050.282'], ['A11.063.438.450', 'A11.118.637.555.567.550.450', 'A11.118.637.555.567.562.200', 'A15.145.229.637.555.567.550.450', 'A15.145.229.637.555.567.562.200', 'A15.382.032.438.450', 'A15.382.490.555.567.550.300', 'A15.382.490.555.567.562.450'], ['B01.050.150.900.649.313.500.380.271'], ['C22.... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Upregulation of AIOLOS induces apoptosis and enhances etoposide chemosensitivity in Jurkat leukemia cells. | T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive neoplastic disorder of immature hematopoietic precursors committed to T-cell lineage. T-ALL accounts for ~15% of pediatric ALL cases and is prone to early relapse. With new and improved treatment protocols, the prognosis of T-ALL has improved particularly in ... | ['Antineoplastic Agents, Phytogenic', 'Apoptosis', 'Cell Differentiation', 'Cell Line, Tumor', 'Cyclin D3', 'Cyclin-Dependent Kinase Inhibitor p21', 'Cyclin-Dependent Kinase Inhibitor p27', 'Drug Resistance, Neoplasm', 'Etoposide', 'G1 Phase Cell Cycle Checkpoints', 'Humans', 'Ikaros Transcription Factor', 'Jurkat Cell... | 25,524,659 | [['D27.505.954.248.179'], ['G04.146.954.035'], ['G04.152'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.644.360.262.150.300', 'D12.776.167.218.150.300', 'D12.776.476.262.150.300'], ['D12.644.360.225.500', 'D12.776.157.687.250', 'D12.776.167.187.500', 'D12.776.476.225.500', 'D12.776.624.776.355.500', 'D12.776.660.720.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Growth hormone receptor inhibition decreases the growth and metastasis of pancreatic ductal adenocarcinoma. | Pancreatic cancer is the only major cancer with very low survival rates (1%). It is the fourth leading cause of cancer-related death. Hyperactivated growth hormone receptor (GHR) levels have been shown to increase the risk of cancer in general and this pathway is a master regulator of key cellular functions like prolif... | ['Carcinoma, Pancreatic Ductal', 'Cell Line, Tumor', 'Cell Movement', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Neoplasm Metastasis', 'Pancreatic Ducts', 'Pancreatic Neoplasms', 'RNA Interference', 'RNA, Small Interfering', 'Receptors, Somatotropin', 'Transfection'] | 25,301,264 | [['C04.557.470.200.025.232.750', 'C04.557.470.615.132.750', 'C04.588.274.761.750', 'C04.588.322.475.750', 'C06.301.761.750', 'C06.689.667.625', 'C19.344.421.750'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650', 'C... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Possible association of psoriasis and reduced bone mineral density due to increased TNF-alpha and IL-6 concentrations. | Psoriasis is a chronic erythematosquamous disease affecting about 2-3% of the population. It is generally considered to be a T cell-mediated disorder. Psoriasis is characterized by Th1-type cytokine pattern with the predominant secretion of IL-2, IL-6, IFN-gamma and TNF-alpha. Such cytokine pattern is sufficient in ind... | ['Bone Density', 'Humans', 'Interleukin-6', 'Models, Biological', 'Psoriasis', 'T-Lymphocytes', 'Tumor Necrosis Factor-alpha'] | 16,844,318 | [['G11.427.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['E05.599.395'], ['C17.800.859.675'], ['A11.118.637.555.567.569', 'A15.145.229.637.555.567.569', 'A15.382.490.555.567.569'], ['D12.644.276.374.500.800', 'D12.644.276.374.750.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recommendations for mass spectrometry data quality metrics for open access data (corollary to the Amsterdam principles). | Policies supporting the rapid and open sharing of proteomic data are being implemented by the leading journals in the field. The proteomics community is taking steps to ensure that data are made publicly accessible and are of high quality, a challenging task that requires the development and deployment of methods for m... | ['Access to Information', 'Benchmarking', 'Guidelines as Topic', 'Mass Spectrometry', 'Proteomics', 'Research Design'] | 22,069,307 | [['I01.880.604.473.352.500.030', 'L01.143.024', 'L01.737.030'], ['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['N04.761.700.350', 'N05.700.350'], ['E05.196.566'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.738'], ['E05.581.50... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Health care expenditures among working-age adults with physical disabilities: variations by disability spans. | BACKGROUND: Data on health care costs for working-age adults with physical disabilities are sparse and the dynamic nature of disability is not captured.OBJECTIVES: To assess the effect of 3 types of disability status (persistent disability, temporary disability, and no disability) on health care expenditures, out-of-po... | ['Adolescent', 'Adult', 'Delivery of Health Care', 'Disabled Persons', 'Female', 'Health Expenditures', 'Humans', 'Insurance, Health', 'Male', 'Middle Aged', 'Reference Values', 'Young Adult'] | 24,060,251 | [['M01.060.057'], ['M01.060.116'], ['N04.590.374', 'N05.300'], ['M01.150'], ['N03.219.151.450', 'N05.300.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343'], ['M01.060.116.630'], ['E05.978.810'], ['M01.060.116.815']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Pathogenesis and the prevention of hypoxic heart contracture]. | The authors studied the development of hypoxic contracture of an isolated isovolumic rat heart and the effect of a water-soluble antioxidant of the class of oxypyridines, OX YP-6, on such a contracture. It was established that a contracture manifested by a rise of diastolic pressure from 5 to 40 mm Hg develops regularl... | ['Animals', 'Antioxidants', 'Cardiomyopathies', 'Contracture', 'Drug Evaluation, Preclinical', 'Hypoxia', 'In Vitro Techniques', 'Male', 'Myocardial Contraction', 'Pyridines', 'Rats', 'Time Factors'] | 7,253,397 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C14.280.238'], ['C05.550.323', 'C05.651.197'], ['E05.290.750', 'E05.337.550'], ['C23.888.852.079'], ['E05.481'], ['G09.330.580', 'G11.427.494.570'], ['D03.383.725'], ['B01.050.150.900.649.313.992.635.505.700'], ['G01.910.857']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Circumferential argon laser photocoagulation for prevention of retinal detachment. | Circumferential argon laser photocoagulation was administered as preventive treatment for retinal detachment in 53 eyes with extensive areas of lattice degeneration and/or retinal breaks and at least one additional high-risk factor for retinal detachment. Laser burns were applied in several continuous rows 360 degrees ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Female', 'Follow-Up Studies', 'Humans', 'Laser Coagulation', 'Male', 'Middle Aged', 'Retinal Degeneration', 'Retinal Detachment', 'Retinal Perforations', 'Risk Factors', 'Treatment Outcome', 'Visual Acuity'] | 7,821,464 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.520.745.410', 'E02.594.530', 'E04.014.520.530', 'E04.350.750.410', 'E04.540.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Functional characterization of muscarinic receptors in murine airways. | 1. The effects of muscarinic receptor antagonists considered to be selective for M1 receptors (pirenzepine; PZ), M2 receptors (AFDX-116), and for M3 receptors (4-diphenyl acetoxy N-methyl-piperidine (4-DAMP)) were used to investigate the existence of muscarinic receptors subtypes in murine airways. Atropine was used as... | ['Administration, Inhalation', 'Airway Resistance', 'Animals', 'Atropine', 'Bronchi', 'Electric Stimulation', 'In Vitro Techniques', 'Isometric Contraction', 'Lung Compliance', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Muscle Contraction', 'Muscle, Smooth', 'Parasympatholytics', 'Parasympathomimetics', 'Piperidines', 'Pi... | 8,495,246 | [['E02.319.267.050'], ['E01.370.386.700.050', 'G09.772.060'], ['B01.050'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['A04.411.125'], ['E05.723.402'], ['E05.481'], ['G11.427.494.472'], ['E01.370.386.700.475', 'G09.772.540'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Space asymmetry as a possible global feature. | A series of reports in the literature indicated symmetry breaking in assemblies of chiral molecules of opposite handedness. These unexpected observations could be accounted for as being generated by the "parity violation" of the nuclear weak force, combined with an autocatalytic amplification process. However, in many ... | ['Chlorates', 'Stereoisomerism'] | 23,580,358 | [['D01.210.300', 'D01.248.497.158.190'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of defibrillation test protocol and test repetition on the probability of meeting implant criteria. | BACKGROUND: Defibrillation testing is a common procedure at defibrillator implant, with the purpose to ensure that each patient receives a device-lead system with a sufficient shock efficacy. The objective of this paper was to study the influence of defibrillation test protocols on the probability of passing implant te... | ['Arrhythmias, Cardiac', 'Data Interpretation, Statistical', 'Defibrillators, Implantable', 'Equipment Failure', 'Equipment Failure Analysis', 'Humans', 'Netherlands', 'Perioperative Care', 'Prosthesis Implantation', 'Treatment Outcome'] | 21,797,895 | [['C14.280.067', 'C23.550.073'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['E07.305.250.159.175', 'E07.305.250.319.175', 'E07.695.202.175'], ['E05.325'], ['E05.325.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.651'], ['E02.760.731',... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Coronaviruses and gastroenteritis: evidence of antigenic relatedness between human enteric coronavirus strains and human coronavirus OC43. | A peculiar pattern of antibody response to human coronavirus (HCV) OC43 and neonatal calf diarrhea coronavirus (NCDCV) was observed in a significantly higher proportion of children with gastroenteritis (GE) than controls. It was directed only to OC43 surface antigens and appeared to be quite different form that observe... | ['Acute Disease', 'Animals', 'Antibodies, Viral', 'Antigens, Surface', 'Antigens, Viral', 'Coronaviridae', 'Coronaviridae Infections', 'Cross Reactions', 'Diarrhea', 'Epitopes', 'Feces', 'Gastroenteritis', 'Guinea Pigs', 'Humans', 'Infant', 'Mice'] | 6,083,436 | [['C23.550.291.125'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D23.050.301'], ['D23.050.327'], ['B04.820.578.500.540'], ['C01.925.782.600.550'], ['G12.122.281'], ['C23.888.821.214'], ['D23.050.550'], ['A12.459'], ['C06.405.205'], ['B01.050.150.900.649... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of hyperbaric oxygen on aerobic performance in a normobaric environment. | The purpose was to examine the acute effects of a hyperbaric oxygen (HBO2) treatment on a) recovery following prolonged exercise and b) aerobic performance in a trained population. Subjects were six male and six female, trained runners with mean Vo2max values of 64.6 +/- 5.6 and 51.9 +/- 6.6 ml x kg(-1) x min(-1), resp... | ['Adult', 'Analysis of Variance', 'Female', 'Heart Rate', 'Humans', 'Hyperbaric Oxygenation', 'Male', 'Oxygen', 'Oxygen Consumption', 'Physical Endurance', 'Running', 'Sex Factors', 'Time Factors'] | 10,642,067 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.880.690.490'], ['D01.268.185.550', 'D01.362.670'], ['G03.680'], ['G11.427.680', 'I03.450.642.845.054.600'], ['G11.427.410.568.610', 'G11... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Observations on thyroid function tests in the elderly. | One hundred elderly men and women living in old people's homes and 95 in a long-stay geriatric hospital were investigated for thyroid function by measuring the serum thyroxine, T-3 uptake and calculating the free thyroxine index. The values obtained were found to be within the normal adult range in 97% of the subjects ... | ['Aged', 'Blood Proteins', 'Female', 'Humans', 'Male', 'Middle Aged', 'Serum Albumin', 'Thyroxine', 'Triiodothyronine'] | 973,588 | [['M01.060.116.100'], ['D12.776.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D12.776.034.841', 'D12.776.124.727'], ['D06.472.931.812', 'D12.125.072.050.767'], ['D06.472.931.740.385', 'D12.125.072.050.767.741.894']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Airway responsiveness in asthma: bronchial challenge with histamine and 4.5% sodium chloride before and after budesonide. | Inhalation of histamine is commonly used to assess the severity of and to monitor treatment of asthma. Histamine causes airways to narrow by acting directly on specific receptors. Hyperosmolar saline causes airways of asthmatics to narrow indirectly by endogenously mediated events that are potentially modified by drugs... | ['Adolescent', 'Adult', 'Asthma', 'Bronchial Provocation Tests', 'Bronchodilator Agents', 'Budesonide', 'Female', 'Forced Expiratory Volume', 'Histamine', 'Humans', 'Male', 'Middle Aged', 'Pregnenediones', 'Saline Solution, Hypertonic', 'Time Factors'] | 9,066,830 | [['M01.060.057'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E01.370.386.700.125'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['D04.210.500.745.745.654.105'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.3... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A new method for carbon isotopic analysis of protein. | The reaction of ninhydrin with amino acids can be used in carbon isotopic studies of protein. The reaction can be applied to extract as carbon dioxide only peptide-bonded carbon in proteinaceous material, thus avoiding most, if not all, contaminants. Test radiocarbon dates on ancient bone indicate that the method provi... | ['Animals', 'Bone and Bones', 'Carbon Isotopes', 'Carbon Radioisotopes', 'Mammals', 'Ninhydrin', 'Paleontology', 'Proteins', 'Radioisotope Dilution Technique'] | 1,990,430 | [['B01.050'], ['A02.835.232', 'A10.165.265'], ['D01.268.150.075', 'D01.496.123'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['B01.050.150.900.649'], ['D02.455.426.559.847.486.487.500', 'D04.615.486.487.500'], ['H01.277.875', 'I01.076.368.584'], ['D12.776'], ['E01.370.384.710', 'E05.484.650']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Role of manual therapy with exercise regime versus exercise regime alone in the management of non-specific chronic neck pain. | To evaluate the role of manual therapy with exercise regime versus exercise regime alone in the management of non-specific chronic neck pain. In this 62 subjects randomized controlled trial 31 subjects in group A received manual therapy (manipulation) with supervised exercise regime whilst 31 subjects in group B perfor... | ['Adult', 'Chronic Pain', 'Exercise Therapy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Musculoskeletal Manipulations', 'Neck Pain'] | 25,410,083 | [['M01.060.116'], ['C23.888.592.612.274'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.190.599', 'E02.779.867', 'E02.831.535.867'], ['C23.888.592.612.553']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Influence of thyroidal status on pituitary content of thyrotropin beta- and alpha-subunit, growth hormone, and prolactin messenger ribonucleic acids. | Thyroidectomized rats were used to study the effects of a single injection of T3 on pituitary mRNA synthesis and hormone secretion. T3 was injected ip at doses of 0, 0.2, 1, or 5 micrograms/100 g body weight, and and animals were killed 24 h later. T3 caused a significant decrease in serum TSH, but caused no significan... | ['Animals', 'Glycoprotein Hormones, alpha Subunit', 'Growth Hormone', 'Male', 'Nucleic Acid Hybridization', 'Pituitary Gland, Anterior', 'Prolactin', 'RNA, Messenger', 'Rats', 'Rats, Inbred Strains', 'Thyroidectomy', 'Thyrotropin', 'Triiodothyronine'] | 2,484,216 | [['B01.050'], ['D06.472.699.322.326.562', 'D06.472.699.322.576.288.750', 'D06.472.699.322.576.463.249', 'D06.472.699.631.525.343.288.750', 'D06.472.699.631.525.343.463.249', 'D06.472.699.631.525.883.249', 'D06.472.699.649.367.562', 'D12.644.548.691.525.343.288.750', 'D12.644.548.691.525.343.463.249', 'D12.644.548.691.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tongue necrosis provoked by ergotamine tartrate and disclosing a giant cell arteritis. | A case of tongue necrosis induced by ergotamine tartrate is reported in a patient who was suffering from an unknown giant cell arteritis (GCA). The role of ergotamine in provoking tongue necrosis in temporal arteritis has only infrequently been considered. The hypothesis concerning ergotamine-induced vasospasm potentia... | ['Aged', 'Ergotamine', 'Female', 'Giant Cell Arteritis', 'Headache', 'Humans', 'Necrosis', 'Tongue Diseases', 'Vasoconstrictor Agents'] | 10,586,137 | [['M01.060.116.100'], ['D03.132.327.412.400', 'D03.633.400.562.500'], ['C10.114.875.700', 'C10.228.140.300.850.500', 'C14.907.253.946.700', 'C14.907.940.090.530', 'C14.907.940.907.700', 'C17.800.862.252', 'C20.111.258.962.800'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.717'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pulsed electric field treatment for bacteria reduction and its impact on hospital wastewater. | During the last years the pulsed electric field (PEF) method entered several fields of application. A promising application is the decontamination of hospital wastewater effluents, which are loaded with pathogenic and increasingly with antibiotic-resistant bacteria. For this study, Pseudomonas putida suspended in buffe... | ['Bacteria', 'Electric Stimulation', 'Pseudomonas putida', 'Waste Disposal, Fluid', 'Water Purification'] | 19,168,200 | [['B03'], ['E05.723.402'], ['B03.440.400.425.625.625.675', 'B03.660.250.580.590.580'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pelargonidin attenuates PDGF-BB-induced aortic smooth muscle cell proliferation and migration by direct inhibition of focal adhesion kinase. | Pelargonidin is a natural red pigment found in fruits and vegetables, and has been reported to exhibit various effects potentially beneficial for human health. However, the possible preventive effects of pelargonidin toward atherosclerosis and mechanisms involved have not been investigated to date. Here, we compared th... | ['Animals', 'Anthocyanins', 'Aorta, Thoracic', 'Becaplermin', 'Cell Movement', 'Cell Proliferation', 'Cells, Cultured', 'Focal Adhesion Kinase 1', 'Human Umbilical Vein Endothelial Cells', 'Humans', 'Muscle, Smooth, Vascular', 'Myocytes, Smooth Muscle', 'Organ Culture Techniques', 'Pigments, Biological', 'Proto-Oncogen... | 24,582,770 | [['B01.050'], ['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['A07.015.114.056.372'], ['D12.644.276.910.650.500', 'D12.776.260.690.500', 'D12.776.467.910.650.500', 'D23.529.910.650.500'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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