Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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CLA isomers inhibit TNFalpha-induced eicosanoid release from human vascular smooth muscle cells via a PPARgamma ligand-like action. | Conjugated linoleic acids (CLAs) were reported to have anti-atherogenic properties in animal feeding experiments. In an attempt to elucidate the molecular mechanisms of these anti-atherogenic effects, the modulatory potential of CLA on cytokine-induced eicosanoid production from smooth muscle cells (SMCs), which contri... | ['Adult', 'Benzamides', 'Chromans', 'Coronary Vessels', 'Cyclooxygenase 1', 'Cyclooxygenase 2', 'Cytochrome P-450 Enzyme System', 'Cytosol', 'Dinoprostone', 'Endothelial Cells', 'Epoprostenol', 'Humans', 'Intramolecular Oxidoreductases', 'Isomerism', 'Linoleic Acids, Conjugated', 'Male', 'NF-kappa B', 'PPAR gamma', 'Ph... | 16,427,740 | [['M01.060.116'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['D03.383.663.283.240', 'D03.633.100.150.240'], ['A07.015.114.269', 'A07.015.908.194'], ['D08.811.600.720.500'], ['D08.811.600.720.750'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['A11.284.430.214.200', 'A... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mating-induced shedding of cell walls, removal of walls from vegetative cells, and osmotic stress induce presumed cell wall genes in Chlamydomonas. | The first step in sexual differentiation of the unicellular green alga Chlamydomonas reinhardtii is the formation of gametes. Three genes, GAS28, GAS30, and GAS31, encoding Hyp-rich glycoproteins that presumably are cell wall constituents, are expressed in the late phase of gametogenesis. These genes, in addition, are ... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cell Wall', 'Chlamydomonas reinhardtii', 'DNA, Algal', 'DNA, Protozoan', 'Gene Expression Regulation, Developmental', 'Genes, Protozoan', 'Glycoproteins', 'Models, Biological', 'Molecular Sequence Data', 'Mutation', 'Osmotic Pressure', 'Protozoan Proteins', 'RNA, Alg... | 16,183,845 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.183'], ['B01.650.940.150.385.650'], ['D13.444.308.148'], ['D13.444.308.442'], ['G05.308.310'], ['G05.360.340.024.340.396', 'G05.360.340.397.500'], ['D09.400.430', 'D12.776.395'], ['E05.599.395'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Differing mechanisms of cAMP- versus seawater-induced oocyte maturation in marine nemertean worms I. The roles of serine/threonine kinases and phosphatases. | Unlike in most animals, oocytes of marine nemertean worms initiate maturation (=germinal vesicle breakdown, GVBD) following an increase, rather than a decrease, in intraoocytic cAMP. To analyze how serine/threonine (Ser/Thr) kinase cascades involving mitogen-activated protein kinase (MAPK), maturation-promoting factor ... | ['Androstadienes', 'Animals', 'Annelida', 'Cyclic AMP', 'Cyclic AMP-Dependent Protein Kinases', 'Maturation-Promoting Factor', 'Mitogen-Activated Protein Kinases', 'Models, Biological', 'Oocytes', 'Phosphatidylinositol 3-Kinases', 'Phosphoprotein Phosphatases', 'Phosphorylation', 'Protein Tyrosine Phosphatases', 'Prote... | 16,902,952 | [['D04.210.500.054.079.129'], ['B01.050'], ['B01.050.500.091'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['D08.811.913.696.620.682.700.646.500.984', 'D12.644.360.250.580', 'D12... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Viral hepatitis: a review of clinical, laboratory and research aspects. | The nature and the diagnosis and prognosis of the two forms of viral hepatitis is discussed. The possibility of transmission of these diseases during dental treatment to other patients or to dentists or their staff is considered and measures to reduce this risk are suggested. | ['Child', 'Dentistry', 'Hepatitis A', 'Hepatitis B', 'Hepatitis B Antibodies', 'Hepatitis B Surface Antigens', 'Hepatitis, Viral, Human', 'Humans', 'Sterilization'] | 274,110 | [['M01.060.406'], ['E06', 'H02.163'], ['C01.925.440.420', 'C01.925.782.687.359.500', 'C06.552.380.705.422'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['D12.776.124.486.485.114.254.450.504', 'D12.776.124.790.651.114.254.450.504', 'D12.776.377.715.548.114.254.450.504'], ['D23.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Spontaneous emergence of social influence in online systems. | Social influence drives both offline and online human behavior. It pervades cultural markets, and manifests itself in the adoption of scientific and technical innovations as well as the spread of social practices. Prior empirical work on the diffusion of innovations in spatial regions or social networks has largely foc... | ['Behavior', 'Humans', 'Internet', 'Online Systems', 'Social Behavior', 'Social Support'] | 20,937,864 | [['F01.145'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['L01.313.500.750.300.742'], ['F01.145.813'], ['I01.880.853.500.600']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
Impulse noise injury prediction based on the cochlear energy. | The current impulse noise criteria for the protection against impulse noise injury do not incorporate an objective measure of hearing protection. A new biomechanically-based model has been developed based on improvement of the Auditory Hazard Assessment Algorithm for the Human (AHAAH) using the integrated cochlear ener... | ['Algorithms', 'Auditory Threshold', 'Biomechanical Phenomena', 'Cochlea', 'Ear', 'Firearms', 'Hearing Loss, Noise-Induced', 'Humans', 'Models, Biological', 'Noise', 'Risk Assessment'] | 26,969,259 | [['G17.035', 'L01.224.050'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['G01.154.090', 'G01.374.089'], ['A09.246.300.246'], ['A01.456.313', 'A09.246'], ['J01.637.870.350'], ['C09.218.458.341.887.460', 'C10.597.751.418.341.887.460', 'C23.888.592.763.393.341.887.460'], ['B01.050.150.900.649.313.9... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Saccharomyces cerevisiae fungemia with granulomas in the bone marrow in a patient undergoing BMT. | A 48-year-old woman underwent allogeneic BMT for CML in chronic phase. One day +180 she experienced fever (37.8 degrees C) and skin rash. Blood cultures from the Hickman catheter and peripheral veins were positive for Saccharomyces cerevisiae. The clinical course of this patient indicates that Saccharomyces should be c... | ['Bone Marrow Diseases', 'Bone Marrow Transplantation', 'Female', 'Fungemia', 'Granuloma', 'Humans', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Middle Aged', 'Saccharomyces cerevisiae', 'Transplantation, Homologous'] | 7,670,407 | [['C15.378.190'], ['E02.095.147.725.040', 'E04.936.580.040'], ['C01.150.703.492.594', 'C01.757.360', 'C23.550.470.790.500.360'], ['C15.604.515.292', 'C23.550.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.250', 'C15.378.190.636.370'], ['M01.060.116.630'], ['B01.300.107.795.785.800', 'B01.300.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Association of AS3MT polymorphisms and the risk of premalignant arsenic skin lesions. | Exposure to naturally occurring inorganic arsenic (iAs), primarily from contaminated drinking water, is considered one of the top environmental health threats worldwide. Arsenic (+3 oxidation state) methyltransferase (AS3MT) is the key enzyme in the biotransformation pathway of iAs. AS3MT catalyzes the transfer of a me... | ['Adolescent', 'Adult', 'Arsenic', 'Case-Control Studies', 'Cross-Sectional Studies', 'DNA', 'Environmental Exposure', 'Female', 'Gene Frequency', 'Genotype', 'Humans', 'Male', 'Methyltransferases', 'Mexico', 'Middle Aged', 'Mouth Mucosa', 'Polymorphism, Single Nucleotide', 'Precancerous Conditions', 'Skin Neoplasms', ... | 19,538,983 | [['M01.060.057'], ['M01.060.116'], ['D01.268.513.249'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D13.444.308'], ['N06.850.460.350'], ['G05.330'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Identification of peptides present in sour milk whey that ameliorate scopolamine-induced memory impairment in mice. | Cognitive impairment is treated with cholinesterase inhibitors that slow cognitive decline but cause significant adverse effects. Functional foods that improve memory without such effects would therefore be valuable. We reported that unidentified components of sour milk whey produced by fermentations using Lactobacillu... | ['Animals', 'Caseins', 'Cholinesterase Inhibitors', 'Chromatography, High Pressure Liquid', 'Cognition Disorders', 'Disease Models, Animal', 'Fermentation', 'Lactobacillus helveticus', 'Male', 'Memory Disorders', 'Mice', 'Peptides', 'Scopolamine', 'Tandem Mass Spectrometry', 'Whey'] | 28,535,697 | [['B01.050'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['E05.196.181.400.300'], ['F03.615.250'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G02.111.158.249', 'G03.191.249'], ['B03.353.750.450.475.400', 'B03.510.460.400.410.475.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Parental history of diabetes modifies the association between abdominal adiposity and hyperglycemia. | OBJECTIVE: To examine whether the association between abdominal obesity and hyperglycemia differs according to the presence of a parental history of diabetes.RESEARCH DESIGN AND METHODS: We conducted a cross-sectional study of 3,068 men and women, aged 20-65 years, without known diabetes who were fasting participants o... | ['Abdomen', 'Adipose Tissue', 'Adult', 'Aged', 'Alcohol Drinking', 'Body Constitution', 'Body Mass Index', 'Cross-Sectional Studies', 'Diabetes Mellitus', 'Educational Status', 'Exercise', 'Female', 'Humans', 'Hyperglycemia', 'Male', 'Middle Aged', 'Netherlands', 'Nuclear Family', 'Obesity', 'Parents', 'Prevalence', 'S... | 11,473,086 | [['A01.923.047'], ['A10.165.114'], ['M01.060.116'], ['M01.060.116.100'], ['F01.145.317.269'], ['E01.370.600.115', 'G07.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C18.452.394.750', '... | ['Anatomy [A]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
In vitro anti-myeloma activity of TRAIL-expressing adipose-derived mesenchymal stem cells. | Recently, genetically modified mesenchymal stem cells (MSCs) have been exploited to deliver anti-cancer bio-drugs directly within the tumour mass. Here, we explored whether adipose-derived MSCs (AD-MSCs), engineered to express the pro-apoptotic ligand TRAIL (also known as TNFSF10), kill multiple myeloma (MM) cells and ... | ['Adipose Tissue', 'Antineoplastic Agents', 'Boronic Acids', 'Bortezomib', 'Cell Death', 'Cell Line, Tumor', 'Cell Proliferation', 'Chemotaxis', 'Coculture Techniques', 'Culture Media, Conditioned', 'Gene Expression', 'Humans', 'Mesenchymal Stem Cells', 'Multiple Myeloma', 'Pyrazines', 'Receptors, TNF-Related Apoptosis... | 22,420,897 | [['A10.165.114'], ['D27.505.954.248'], ['D01.029.260.110', 'D01.132.285', 'D02.203.200'], ['D01.029.260.110.500', 'D01.132.285.500', 'D02.203.200.500', 'D03.383.679.450'], ['G04.146'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Women aging together in community. | At a fiftieth birthday party 17 years ago, a group of women--lesbian, bisexual, and straight--decided to create a conscious community in which they could age together. The group, where they discuss this process and support each other, is politically and personally meaningful, and a buffer against the isolation and powe... | ['Aged', 'Aging', 'California', 'Communication', 'Conflict, Psychological', 'Female', 'Friends', 'Humans', 'Life Change Events', 'Middle Aged', 'Organizational Case Studies', 'Self-Help Groups', "Women's Health"] | 19,042,738 | [['M01.060.116.100'], ['G07.345.124'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['F01.145.209', 'L01.143'], ['F01.658.209'], ['M01.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458.410'], ['M01.060.116.630'], ['N03.349.380.710', 'N05.715.360.455'], ['N03.540.782'], ['N01.400.900']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Chronic dry eye and regression after laser in situ keratomileusis for myopia. | PURPOSE: To examine the relationship between chronic dry eye and refractive regression after laser in situ keratomileusis (LASIK) for myopia.SETTING: Excimer Laser Vision Centre and Centre for Eye Research, Queensland University of Technology, Brisbane, Australia.METHODS: This study was based on a retrospective analysi... | ['Adolescent', 'Adult', 'Aged', 'Chronic Disease', 'Cornea', 'Dry Eye Syndromes', 'Female', 'Fluorophotometry', 'Humans', 'Keratomileusis, Laser In Situ', 'Male', 'Middle Aged', 'Myopia', 'Ophthalmic Solutions', 'Postoperative Complications', 'Practice Guidelines as Topic', 'Retrospective Studies', 'Risk Factors'] | 15,050,267 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C23.550.291.500'], ['A09.371.060.217'], ['C11.496.260'], ['E01.370.380.255', 'E05.196.712.516.600.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594.480.750', 'E04.014.520.480.750', 'E04.378.500.750', 'E04.540.825.437.374'], ['M01.060.116.630'], [... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Psychiatric comorbidity among patients with hypochondriasis. | The purpose of this study was to determine the nature and extent of comorbidity among patients with DSM-III-R hypochondriasis and to examine the relationships between this disorder and coexisting psychiatric illness. For this purpose, patients seen in a general medicine clinic were screened using measures of hypochondr... | ['Adult', 'Anxiety Disorders', 'Comorbidity', 'Cross-Sectional Studies', 'Depressive Disorder', 'Female', 'Humans', 'Hypochondriasis', 'Incidence', 'Male', 'Mass Screening', 'Mental Disorders', 'Middle Aged', 'Patient Care Team', 'Personality Assessment', 'Psychometrics', 'Sick Role', 'Somatoform Disorders'] | 8,039,697 | [['M01.060.116'], ['F03.080'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.875.450'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Learning to look: Evaluating the student experience of an interactive image appraisal activity. | INTRODUCTION: Student radiographers have expressed difficulty in performing image appraisal tasks. The purpose of this study was to investigate the value of a workshop delivered to level 4 undergraduate students. All students completed an image appraisal activity, inputting their appraisal into software that displayed ... | ['Clinical Competence', 'Focus Groups', 'Humans', 'Learning', 'Radiography', 'Radiology', 'Students, Medical', 'Visual Perception'] | 31,582,238 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['E01.370.350.700'], ['H02.403.740'], ['M01.848.769.602'], ['F02.463.593.932']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
[The health problems related to atmospheric pollution in large industrial regions of Bulgaria]. | Epidemiological studies are performed in some towns and large industrial regions of the country, in order to establish the changes in the health state of the population, due to atmospheric pollutants. The attention is directed to regions with national industrial branches, most intensively polluting the atmospheric air ... | ['Air Pollution', 'Bulgaria', 'Chemical Industry', 'Environmental Exposure', 'Environmental Health', 'Humans', 'Industry', 'Metallurgy', 'Paper'] | 1,796,104 | [['N06.850.460.100'], ['Z01.542.248.180'], ['J01.576.655.437'], ['N06.850.460.350'], ['H02.229'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.576'], ['J01.576.655.875.400'], ['J01.637.650']] | ['Health Care [N]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Mitochondrial transcription factor A and respiratory complex IV increase in response to exercise training in humans. | Protein levels of mitochondrial transcription factor A (Tfam) and nuclear- and mitochondrial-encoded subunits of respiratory chain complex IV (COX I and COX IV) as well as citrate synthase activity were analysed in muscle biopsy samples of vastus lateralis in six healthy male subjects before and after 4 weeks of one-le... | ['Adult', 'Citrate (si)-Synthase', 'DNA-Binding Proteins', 'Electron Transport Complex I', 'Electron Transport Complex IV', 'Energy Metabolism', 'Exercise', 'Humans', 'Male', 'Mitochondria, Muscle', 'Mitochondrial Proteins', 'NADH, NADPH Oxidoreductases', 'Nuclear Proteins', 'Trans-Activators', 'Transcription Factors',... | 11,692,267 | [['M01.060.116'], ['D08.811.913.050.368'], ['D12.776.260'], ['D05.500.562.249', 'D08.811.600.250.500.500', 'D08.811.682.608.504', 'D12.776.157.427.374.375.863', 'D12.776.157.530.450.250.875.300', 'D12.776.331.199.500', 'D12.776.543.277.500.500', 'D12.776.543.585.450.250.875.437', 'D12.776.556.579.374.375.140'], ['D05.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
The Streptococcus pyogenes capsule is required for adhesion of bacteria to virus-infected alveolar epithelial cells and lethal bacterial-viral superinfection. | An apparent worldwide resurgence of invasive group A Streptococcus (GAS) infections remains unexplained. However, we recently demonstrated in mice that when an otherwise nonlethal intranasal GAS infection is preceded by a nonlethal influenza A virus (IAV) infection, induction of lethal invasive GAS infections is often ... | ['Animals', 'Bacterial Adhesion', 'Bacterial Capsules', 'Bacterial Proteins', 'Cell Line', 'Epithelial Cells', 'Female', 'Genes, Bacterial', 'Humans', 'Influenza A virus', 'Influenza, Human', 'Mice', 'Mice, Inbred BALB C', 'Mutagenesis', 'Mutation', 'N-Acetylneuraminic Acid', 'Streptococcal Infections', 'Streptococcus ... | 15,385,511 | [['B01.050'], ['G06.099.050'], ['A20.186'], ['D12.776.097'], ['A11.251.210'], ['A11.436'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.405.400'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['B01.050... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A Japanese Burkitt's lymphoma with t(2;8) and EBNA. | A 56-year-old Japanese man was admitted to the hospital with a large mass in his right axilla. Histological investigation revealed that it was a Burkitt's lymphoma. Ultrastructures of the tumor cells showed immature lymphoid features with frequent lipid droplets within the cytoplasms. Virological studies before the tre... | ['Antigens, Neoplasm', 'Antigens, Viral', 'Burkitt Lymphoma', 'Chromosomes, Human, 6-12 and X', 'Epstein-Barr Virus Nuclear Antigens', 'Herpesvirus 4, Human', 'Humans', 'Karyotyping', 'Male', 'Microscopy, Electron', 'Middle Aged', 'Translocation, Genetic'] | 3,008,496 | [['D23.050.285'], ['D23.050.327'], ['C01.925.256.466.313.165', 'C01.925.928.313.165', 'C04.557.386.480.150.165', 'C15.604.515.569.480.150.165', 'C20.683.515.761.480.150.165'], ['A11.284.187.520.300.325', 'G05.360.162.520.300.325'], ['D23.050.290.249', 'D23.050.327.300'], ['B04.280.210.400.500.450', 'B04.280.382.400.500... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Normotherm continuous blood cardioplegia for 4 hours in an in vivo pig model. | Warm, continuous blood cardioplegia should theoretically maintain cardiac arrest for hours without ischaemic or hypothermic injury. In the absence of in vivo studies of myocardial metabolism and ultrastructural and/or functional preservation during and after more than 2 hours of cardiac arrest and after weaning from by... | ['Animals', 'Blood Pressure', 'Constriction', 'Coronary Vessels', 'Creatine Kinase', 'Heart Arrest, Induced', 'L-Lactate Dehydrogenase', 'Models, Biological', 'Swine'] | 8,976,032 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.225'], ['A07.015.114.269', 'A07.015.908.194'], ['D08.811.913.696.640.150'], ['E04.100.376.374', 'E04.928.220.360'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['E05.599.395'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A critical role for IL-21 in regulating immunoglobulin production. | The cytokine interleukin-21 (IL-21) is closely related to IL-2 and IL-15, and their receptors all share the common cytokine receptor gamma chain, gammac, which is mutated in humans with X-linked severe combined immunodeficiency disease (XSCID). We demonstrate that, although mice deficient in the receptor for IL-21 (IL-... | ['Animals', 'Antibody-Producing Cells', 'B-Lymphocytes', 'CD4-Positive T-Lymphocytes', 'Cells, Cultured', 'Gene Targeting', 'Genetic Diseases, X-Linked', 'Humans', 'Immunization', 'Immunoglobulin E', 'Immunoglobulin G', 'Immunoglobulins', 'Immunologic Memory', 'Interferon-gamma', 'Interleukin-21 Receptor alpha Subunit'... | 12,446,913 | [['B01.050'], ['A11.063', 'A15.382.032'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.251'], ['E05.393.335'], ['C16.320.322'], ['B01.050.1... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Analysis of Shear Flow-induced Migration of Murine Marginal Zone B Cells In Vitro. | Marginal zone B cells (MZBs) are a population of B cells that reside in the mouse splenic marginal zones that envelop follicles. To reach the follicles, MZBs must migrate up the shear force of blood flow. We present here a method for analyzing this flow-induced MZB migration in vitro. First, MZBs are isolated from the ... | ['Animals', 'B-Lymphocytes', 'Cell Movement', 'Cells, Cultured', 'Chemotaxis', 'Lymphoid Tissue', 'Mice', 'Spleen', 'Time-Lapse Imaging'] | 30,531,718 | [['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['A10.549', 'A15.382.52... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Dynamic Signal Compression for Robust Motion Vision in Flies. | Sensory systems need to reliably extract information from highly variable natural signals. Flies, for instance, use optic flow to guide their course and are remarkably adept at estimating image velocity regardless of image statistics. Current circuit models, however, cannot account for this robustness. Here, we demonst... | ['Animals', 'Drosophila melanogaster', 'Motion Perception', 'Neural Networks, Computer', 'Neurons', 'Vision, Ocular'] | 31,928,873 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['F02.463.593.932.567'], ['G17.485', 'L01.224.050.375.605'], ['A08.675', 'A11.671'], ['F02.830.816.964', 'G02.111.820.480.900', 'G04.835.480.900', 'G11.561.790.964', 'G14.935']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Complement mediated apoptosis leads to the loss of retinal ganglion cells in animal model of glaucoma. | This study investigated the role of complement in the protection of retinal ganglion cells (RGCs) in chronic ocular hypertension model of glaucoma. Intraocular pressure (IOP) was elevated in the right eye of Lewis rats by laser photocoagulation (two treatments, 7days apart) of episcleral and limbal veins. Left eye did ... | ['Animals', 'Apoptosis', 'Blotting, Western', 'Calcium', 'Complement System Proteins', 'Disease Models, Animal', 'Glaucoma', 'Immunohistochemistry', 'In Situ Nick-End Labeling', 'Rats', 'Rats, Inbred Lew', 'Retinal Ganglion Cells'] | 21,821,293 | [['B01.050'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.124.486.274'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C11.525.381'], ['E01.370.225.500.607.512', 'E01.370.225... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A polymerase chain reaction-based assay for detection of Wuchereria bancrofti in human blood and Culex pipiens. | Human blood samples and indoor-resting Culex pipiens were collected in 33 randomly selected houses from different sectors of a village in the Nile Delta of Egypt which was endemic for Wuchereria bancrofti. Blood was also collected from subjects with no history of living in filarial endemic areas. Human blood samples we... | ['Animals', 'Culex', 'Female', 'Filariasis', 'Humans', 'Microfilariae', 'Polymerase Chain Reaction', 'Wuchereria bancrofti'] | 9,196,756 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.225'], ['C01.610.335.508.700.750.361'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.500.500.294.400.937.463.470', 'B05.525'], ['E05.393.620.500'], ['B01.050.500.500.294.400.937.463.708.150']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulation of cholesteryl ester metabolism in the hamster liver. | Neutral cholesteryl ester hydrolase activity has been described in the cytosolic and microsomal fraction of rat liver, but the relationship of these activities to other parameters of hepatic cholesterol metabolism is not known. We have studied this in the hamster by manipulating the flux of cholesterol across the liver... | ['Animals', 'Carboxylic Ester Hydrolases', 'Cholesterol Esters', 'Cholestyramine Resin', 'Coconut Oil', 'Cricetinae', 'Cytosol', 'Diet', 'Dietary Fats', 'Male', 'Microsomes, Liver', 'Plant Oils', 'Sterol Esterase', 'Sterol O-Acyltransferase'] | 2,340,303 | [['B01.050'], ['D08.811.277.352.100'], ['D04.210.500.247.222.284.200', 'D04.210.500.247.808.197.200', 'D10.570.938.208.250'], ['D05.750.716.579.159', 'D25.720.716.579.159', 'J01.637.051.720.716.579.159'], ['D10.627.700.186'], ['B01.050.150.900.649.313.992.635.075.250'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Development and utilization of the Nominal Standard Dose for the tolerance dosage to healthy tissue in radiotherapy]. | The utilization of the Ellis-formula for the determination of the tolerance of normal connective tissue is described. Beyond this, the formula is adapted to so-called critical organs. The individual suppositions implicated by the Ellis-formula are commented. Because of the verifyable congruency of the Ellis-formula wit... | ['Computers', 'Dose-Response Relationship, Radiation', 'Humans', 'Radiation Injuries', 'Radiotherapy Dosage', 'Skin', 'Skin Neoplasms'] | 1,258,089 | [['L01.224.230.260'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.733', 'G01.750.748.500', 'N06.850.460.350.850.500', 'N06.850.810.300.360'], ['E02.815.639'], ['A17.815'], ['C04.588.805', 'C17.800.882']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Association-dissociation of histone oligomers. A spin label study. | The spin label method has been used to obtain information about conformational changes of histone oligomers taking advantage of the fact that at a low ionic strength and in the presence of other histones about 45% of cysteine residues of histone H3 react with the 3-maleimido-2,2,5,5-tetramethyl-1-pyrrolidinyloxyl spin ... | ['Cysteine', 'Electron Spin Resonance Spectroscopy', 'Guanidines', 'Histones', 'Macromolecular Substances', 'Nucleosomes', 'Osmolar Concentration', 'Protein Binding', 'Protein Conformation', 'Thymus Gland'] | 6,099,335 | [['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['E05.196.867.519.274'], ['D02.078.370'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['D05'], ['A11.284.430.106.279.345.190.160.180.625', 'D12.776.664.224.550', 'G05.360.160.180.625'], ['G02.640'], ['G02.111.679', 'G0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pulmonary adenocarcinoma: review of 106 cases and proposed new classification. | The gross and microscopic appearances of 106 resected pulmonary adenocarcinomas were reviewed and correlated with postoperative survival. Instead of using an established classification based on histological pattern, the tumours were categorised by cellular morphology and site as either parenchymal adenocarcinoma (67%),... | ['Adenocarcinoma', 'Adult', 'Aged', 'Bronchial Neoplasms', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged'] | 3,818,979 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['C04.588.894.797.520.109', 'C08.127.265', 'C08.785.520.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Protective activation of the endocannabinoid system during ischemia in dopamine neurons. | Endocannabinoids act as neuroprotective molecules promptly released in response to pathological stimuli. Hence, they may represent one component of protection and/or repair mechanisms mobilized by dopamine (DA) neurons under ischemia. Here, we show that the endocannabinoid 2-arachidonoyl-glycerol (2-AG) plays a key rol... | ['Amidohydrolases', 'Animals', 'Arachidonic Acids', 'Benzoxazines', 'Brain Ischemia', 'Cannabinoid Receptor Modulators', 'Dopamine', 'Electrophysiology', 'Endocannabinoids', 'Glycerides', 'In Vitro Techniques', 'Male', 'Mice', 'Mice, Knockout', 'Morpholines', 'Naphthalenes', 'Neurons', 'Piperidines', 'Pyrazoles', 'Rats... | 16,762,556 | [['D08.811.277.087'], ['B01.050'], ['D10.251.355.255.100', 'D10.251.355.310.166'], ['D03.383.533.249', 'D03.633.100.209'], ['C10.228.140.300.150', 'C14.907.253.092'], ['D27.505.519.625.085', 'D27.505.696.399.472.188'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['H01.158.344.528'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Cholinergic traits in rat mandibular processes observed by electron microscopy. | Cholinergic traits in rat mandibular processes were examined histochemically, under the electron microscope, at early developmental stages (Stages 20 to 23, by Christie's nomenclature). The histochemical reaction for detection of enzymes was performed by the thiocholine method. Nonspecific cholinesterase (EC 3.1.1.8) a... | ['Animals', 'Choline', 'Cholinesterases', 'Endothelium', 'Epithelium', 'Histocytochemistry', 'Mandible', 'Mesoderm', 'Microscopy, Electron', 'Morphogenesis', 'Neural Crest', 'Rats', 'Rats, Inbred Strains', 'Trigeminal Nerve'] | 3,631,533 | [['B01.050'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['D08.811.277.352.100.170'], ['A10.272.491'], ['A10.272'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['A02.835.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Lift-off Test Results After Lesser Tuberosity Osteotomy Versus Subscapularis Peel in Primary Total Shoulder Arthroplasty. | BACKGROUND: The ideal method for management of the subscapularis tendon during anatomic total shoulder arthroplasty (TSA) remains controversial.METHODS: In a retrospective cohort study, primary anatomic TSA procedures performed with either a subscapularis peel or a lesser tuberosity osteotomy from 2002 to 2010 were rev... | ['Arthroplasty, Replacement, Shoulder', 'Female', 'Follow-Up Studies', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Osteotomy', 'Postoperative Complications', 'Radius', 'Retrospective Studies', 'Rotator Cuff', 'Treatment Outcome'] | 28,234,638 | [['E04.555.110.110.299', 'E04.650.110.299', 'E04.680.101.110.299'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.53... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Genome-wide imaging association study implicates functional activity and glial homeostasis of the caudate in smoking addiction. | BACKGROUND: Nearly 6 million deaths and over a half trillion dollars in healthcare costs worldwide are attributed to tobacco smoking each year. Extensive research efforts have been pursued to elucidate the molecular underpinnings of smoking addiction and facilitate cessation. In this study, we genotyped and obtained bo... | ['Adult', 'Behavior, Addictive', 'Caudate Nucleus', 'Emotions', 'Female', 'Genome-Wide Association Study', 'Homeostasis', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Neuroglia', 'Reward', 'Signal Transduction', 'Smoking'] | 28,927,378 | [['M01.060.116'], ['F01.145.527.100.120'], ['A08.186.211.200.885.287.249.487.550.184'], ['F01.470'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['G07.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sick sinus syndrome due to cardiac amyloidosis. | In a patient suffering from cardiac amyloidosis a case of sick sinus syndrome, manifested by markedly prolonged recovery time of the sinus node, was documented by an atrial pacing study. The first A-V junctional escape interval was markedly prolonged following the termination of the atrial pacing, pointing to a coexist... | ['Amyloidosis', 'Arrhythmia, Sinus', 'Cardiomyopathies', 'Electrocardiography', 'Female', 'Humans', 'Middle Aged', 'Pacemaker, Artificial', 'Syndrome'] | 657,173 | [['C18.452.845.500'], ['C14.280.067.093', 'C23.550.073.093'], ['C14.280.238'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E07.305.250.750'], ['C23.550.288.500']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[A retrospective study of patients with epidemic optic neuropathy in a health area]. | The sample of 104 patients who were diagnosed optic epidemic neuropathy at the health area of the "Rampa" Polyclinic in 1993 was reviewed. 50 of them were studied again. Visual acuity as well as the sensitivity to contrast by the Pelli Robson's method were explored. Ishihara's color-vision test was applied and an ophth... | ['Color Perception', 'Cuba', 'Disease Outbreaks', 'Fundus Oculi', 'Humans', 'Optic Neuritis', 'Peripheral Nervous System Diseases', 'Retrospective Studies', 'Visual Acuity'] | 10,349,459 | [['F02.463.593.932.217'], ['Z01.107.084.900.225', 'Z01.639.880.225'], ['N06.850.290'], ['A09.371.729.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.292.700.550', 'C11.640.576'], ['C10.668.829'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750... | ['Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
A novel nitro-oxy substituted analogue of rofecoxib reduces human colon cancer cell growth. | Rofecoxib is a specific COX-2 inhibitor able to exert antiproliferative activity against colorectal cancer cells. It was withdrawn from the market after the demonstration of an increased risk of cardiovascular complications after prolonged use. Nevertheless, it remains an interesting compound for laboratory research as... | ['4-Butyrolactone', 'Antineoplastic Agents', 'Cadherins', 'Cell Line, Tumor', 'Cell Proliferation', 'Cell Survival', 'Colonic Neoplasms', 'Cyclooxygenase 2', 'Cyclooxygenase 2 Inhibitors', 'Gene Expression', 'Humans', 'Mitogen-Activated Protein Kinases', 'Nitrates', 'Phosphorylation', 'Proto-Oncogene Proteins c-myc', '... | 22,002,318 | [['D02.540.150', 'D03.383.312.150'], ['D27.505.954.248'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selected qualitative and biochemical parameters of cryopreserved semen of Holstein-Friesian (HF) AI bulls. | Selected qualitative and biochemical parameters were determined in cryopreserved semen used for artificial insemination, sampled from 120 bulls reared at the Animal Breeding and Insemination Center in Bydgoszcz. The total average motility of the analyzed sperm samples was determined at 62.51%. The percentage of motile ... | ['Animals', 'Cattle', 'Cryopreservation', 'Insemination, Artificial', 'Male', 'Semen', 'Semen Analysis', 'Semen Preservation'] | 25,928,933 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['E02.875.800.937', 'E05.820.800.937', 'G08.686.784.363.492'], ['A12.200.732'], ['E01.370.225.992', 'E05.200.992'], [... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical and pathological differences between Mikulicz's disease and Sj?gren's syndrome. | OBJECTIVE: Mikulicz's disease (MD) has been included within the diagnosis of primary Sj?gren's syndrome (SS), but represents a unique condition involving enlargement of the lachrymal and salivary glands and characterized by few autoimmune reactions and good responsiveness to glucocorticoids. We have previously describe... | ['Aged', 'Female', 'Glucocorticoids', 'Humans', 'Immunoglobulin G', 'Immunohistochemistry', 'Interferon-gamma', 'Interleukin-4', 'Lacrimal Apparatus', 'Male', 'Middle Aged', "Mikulicz' Disease", 'Salivary Glands', "Sjogren's Syndrome"] | 15,509,627 | [['M01.060.116.100'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Brief historical sketch of chromosomal translocations and tumors. | The discovery of chromosomes emerged from the cytological analysis of mitosis in the 1870s. At the turn of the 20th century, cytologists and geneticists established that chromosomes carried the hereditary material. In the early 20th century, Theodore Boveri, recognizing the nonequivalence of individual chromosomes, beg... | ['Chromosome Aberrations', 'Genetics', 'History, 19th Century', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Neoplasms', 'Translocation, Genetic'] | 18,647,993 | [['C23.550.210', 'G05.365.590.175'], ['H01.158.273.343'], ['K01.400.504.937'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['C23.550.210.870', 'G05.365.590.175.870', 'G05.558.860']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Humanities [K]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Serum lactate dehydrogenase with a systemic inflammation score is useful for predicting response and survival in patients with newly diagnosed diffuse large B-cell lymphoma. | We evaluated the relationship between serum lactate dehydrogenase (LDH) level with systemic inflammation score and survival in 213 patients with diffuse large B-cell lymphoma (DLBCL) receiving R-CHOP chemotherapy. The patients were classified into 3 groups based on LDH with the Glasgow Prognostic Score (L-GPS). A score... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Antibodies, Monoclonal, Murine-Derived', 'Antineoplastic Combined Chemotherapy Protocols', 'C-Reactive Protein', 'Cyclophosphamide', 'Doxorubicin', 'Female', 'Humans', 'Inflammation Mediators', 'Lactate Dehydrogenases', 'Lymphoma, Large B-Cell, Diffuse', 'Male', 'Mi... | 24,969,101 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.124.486.485.114.224.075', 'D12.776.124.790.651.114.224.075', 'D12.776.377.715.548.114.224.284'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['D02.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Relation between early and advanced gastric cancer. | Of 75 consecutive inpatients with gastric carcinoma during a 3.5 year period, 40 underwent operation with the intention of cure, 5 had palliative gastric resection and 30 had exploratory celiotomy only. Early gastric cancer was found in 11 cases, that is, 15 percent of patients with gastric carcinoma or 24 percent of p... | ['Adult', 'Aged', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Palliative Care', 'Prognosis', 'Stomach Neoplasms', 'Sweden', 'Time Factors'] | 6,158,879 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['E02.760.666', 'N02.421.585.666'], ['E01.789'], ['C04.588.274.476.767', 'C06.301.37... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Therapist actions that address initially poor therapeutic alliances in psychotherapy. | The authors studied six patients treated in time-limited dynamic psychotherapy who had initially poor therapeutic alliance scores; three patients went on to have improved alliances and good outcomes, and three had unimproved alliances and poor outcomes. The therapist actions that most strongly differentiated the two gr... | ['Adjustment Disorders', 'Adult', 'Aged', 'Attitude of Health Personnel', 'Cooperative Behavior', 'Defense Mechanisms', 'Female', 'Grief', 'Guilt', 'Humans', 'Middle Aged', 'Outcome and Process Assessment, Health Care', 'Physician-Patient Relations', 'Psychiatric Status Rating Scales', 'Psychoanalytic Therapy', 'Psycho... | 4,025,587 | [['F03.950.500'], ['M01.060.116'], ['M01.060.116.100'], ['F01.100.050', 'N05.300.100'], ['F01.145.813.115'], ['F01.393'], ['F01.470.142.110'], ['F01.470.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N04.761.559', 'N05.715.360.575'], ['F01.829.401.650.675', 'N05.300.660.625'], ['F04.711.... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Monoclonal gammapathies in long-term surviving rhesus monkeys after lethal irradiation and bone marrow transplantation. | Late effects of total body irradiation and subsequent autologous bone marrow transplantation on the development of age-related monoclonal gammapathies (MG) were studied in 14 long-term surviving Rhesus monkeys. Together with 27 untreated control monkeys, they have been followed up for more than 20 years. In contrast wi... | ['Animals', 'Bone Marrow Transplantation', 'Immunoglobulin Isotypes', 'Longitudinal Studies', 'Macaca mulatta', 'Paraproteinemias', 'Radiotherapy', 'Whole-Body Irradiation'] | 2,070,572 | [['B01.050'], ['E02.095.147.725.040', 'E04.936.580.040'], ['D12.776.124.486.485.114.619', 'D12.776.124.790.651.114.619', 'D12.776.377.715.548.114.619'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['C15.378.147.780',... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Morphological characteristics and physiological properties of aflatoxin B1 producing and non-producing Aspergillus flavus strains]. | Comparison between about 80 strains of Aspergillus flavus, belonging to the series flavus and oryzae, obtained from international collections but also isolated from French or African substrates revealed the following observations: 1. Cultural and morphological characteristics of toxicogenic and atoxicogenic strains of ... | ['Aflatoxin B1', 'Aflatoxins', 'Aspergillus flavus'] | 3,932,861 | [['D03.383.663.283.119.075', 'D03.633.100.150.119.075', 'D23.946.587.142.075'], ['D03.383.663.283.119', 'D03.633.100.150.119', 'D23.946.587.142'], ['B01.300.381.081.170']] | ['Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Incidence of renal dysfunction over 6 months in patients with chronic heart failure due to left ventricular systolic dysfunction: contributing factors and relationship to prognosis. | AIMS: To determine the prevalence and incidence of renal dysfunction (RD) in patients with chronic heart failure (CHF), to identify contributory factors and predictors of worsening renal function (WRF), and to explore the relationship between RD and mortality.METHODS AND RESULTS: Prospective data on 1216 patients with ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Chronic Disease', 'Creatinine', 'Cross-Sectional Studies', 'Female', 'Follow-Up Studies', 'Glomerular Filtration Rate', 'Heart Failure', 'Humans', 'Incidence', 'Kidney Diseases', 'Male', 'Middle Aged', 'Prognosis', 'Regression, Psychology', 'Ventricular Dysfunction, Left'] | 16,364,971 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.550.291.500'], ['D03.383.129.308.207'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.390.400.300', 'G08.852.357'], ... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The disposition and kinetics of intravenous N-acetylcysteine in patients with paracetamol overdosage. | Seventeen patients received standard treatment with intravenous N-acetylcysteine for 18 episodes of severe poisoning with paracetamol (acetaminophen). The dose of N-acetylcysteine was 150 mg/kg given in 15 min followed by 50 mg/kg in 4 h and 100 mg/kg over the next 16 h. Liver damage was absent or mild on 13 occasions ... | ['Acetaminophen', 'Acetylcysteine', 'Adolescent', 'Adult', 'Aged', 'Chemical and Drug Induced Liver Injury', 'Female', 'Humans', 'Injections, Intravenous', 'Liver Function Tests', 'Male'] | 2,598,989 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['D02.886.030.230.259', 'D12.125.166.230.259'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['E01.370.372.460']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evidence for cAMP-dependent protein kinase in the dinoflagellate, Amphidinium operculatum. | A cAMP dependent protein kinase (PKA) was identified in the dinoflagellate Amphidinium operculum. In vitro kinase activity towards kemptide, a PKA-specific substrate, was not detectable in crude lysates. However, fractionation of dinoflagellate extracts by gel filtration chromatography showed PKA-like activity toward k... | ['Animals', 'Blotting, Western', 'Chromatography, Gel', 'Cyclic AMP-Dependent Protein Kinases', 'Dinoflagellida', 'Immunoenzyme Techniques', 'Molecular Weight', 'Oligopeptides'] | 12,431,399 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.196.181.400.250'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['B01.043.214'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['G02.494'], ['D1... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Functional assessment of human femoral arteries after cryopreservation. | PURPOSE: An established method of cryostorage that might preserve the vascular and endothelial responses of human femoral arteries (HFAs) to be transplanted as allografts was studied.METHODS: HFAs were harvested from multiorgan donors and stored at 4 degrees C in Belzer solution before cryostorage. One hundred eleven H... | ['Cryopreservation', 'Endothelium, Vascular', 'Femoral Artery', 'Graft Survival', 'Humans', 'Nitric Oxide', 'Transplantation, Homologous', 'Vasoconstriction', 'Vasoconstrictor Agents'] | 9,719,322 | [['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['A07.015.700.500', 'A10.272.491.355'], ['A07.015.114.351'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.339.387', 'D01.625.550.500', 'D01.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cardiac microdialysis in isolated rat hearts: interstitial purine metabolites during ischemia. | Cardiac microdialysis is a recently developed technique that allows intramyocardial interstitial fluid (ISF) to be sampled via the implantation and perfusion of a small, hollow dialysis fiber within the myocardium. The purpose of this paper is to describe initial studies using cardiac microdialysis in the isolated perf... | ['Adenine', 'Animals', 'Coronary Disease', 'Dialysis', 'Extracellular Space', 'In Vitro Techniques', 'Myocardium', 'Osmolar Concentration', 'Perfusion', 'Pressure', 'Purines', 'Rats'] | 1,621,849 | [['D03.633.100.759.138'], ['B01.050'], ['C14.280.647.250', 'C14.907.585.250'], ['E05.196.353', 'G02.186'], ['A10.082.500', 'A11.284.295'], ['E05.481'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['G02.640'], ['E05.680'], ['G01.374.715'], ['D03.633.100.759'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activation of p38MAPK signaling cascade in a VSMC injury model: role of p38MAPK inhibitors in limiting VSMC proliferation. | INTRODUCTION: P38 mitogen-activated protein kinase (MAPK) has a crucial role in regulating signaling pathways implicated in the cellular events leading to restenosis. We examine p38MAPK activation in response to vascular cell injury, its biological effects and determine whether selective p38MAPK inhibitors, SB220025/SB... | ['Calcium-Calmodulin-Dependent Protein Kinases', 'Cell Division', 'Cell Survival', 'Cells, Cultured', 'Enzyme Inhibitors', 'Humans', 'Imidazoles', 'Muscle, Smooth, Vascular', 'Phosphorylation', 'Pyridines', 'Pyrimidines', 'p38 Mitogen-Activated Protein Kinases'] | 15,966,085 | [['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.346'], ['A11.251'], ['D27.505.519.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.308'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.4... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sleep science, schedules, and safety in hospitals: challenges and solutions for pediatric providers. | Sleep deprivation is common among resident physicians and clinical fellows. Current evidence about sleep science, performance, shift work, and medical errors consistently demonstrates positive impact from reduction of excessive duty hours, particularly when shift length is shortened. This article provides an overview o... | ['Child', 'Fatigue', 'Hospital Administration', 'Humans', 'Internship and Residency', 'Medical Errors', 'Patient Safety', 'Pediatrics', 'Personnel Staffing and Scheduling', 'Sleep', 'Sleep Deprivation', 'United States', 'Work Schedule Tolerance', 'Workload'] | 23,116,528 | [['M01.060.406'], ['C23.888.369'], ['H02.309', 'N02.278.216.500', 'N04.452.442.452'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['N02.421.450'], ['N06.850.135.060.075.399'], ['H02.403.670'], ['I03.946.225', 'N04.452.677.650'], ['F02.830.855', 'G11.561.803'], ['C10.... | ['Named Groups [M]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
[The psychometric properties of the Turkish version of Myocardial Infarction Dimensional Assessment Scale (MIDAS)]. | OBJECTIVE: The purpose of this study was to describe the psychometric properties of the Myocardial Infarction Dimensional Assessment Scale (MIDAS).METHODS: This is a methodological cultural adaptation study. The MIDAS consists of 35-items covering seven domains: physical activity, insecurity, emotional reaction, depend... | ['Adaptation, Psychological', 'Adult', 'Aged', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Psychiatric Status Rating Scales', 'Psychometrics', 'Quality of Life', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Turkey'] | 21,652,294 | [['F01.058'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['F04.711.513.653'], ['F04.711.780'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E05.318.370.7... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
High-molecular-weight hyaluronan--a valuable tool in testing the antioxidative activity of amphiphilic drugs stobadine and vinpocetine. | The antioxidative activity of stobadine and vinpocetine was studied in vitro by measuring their inhibition effect on the depolymerization of the high-molecular-weight hyaluronan by hydroxyl radicals. The radicals were generated by the Cu(2+)-H2O2 system. Hyaluronan depolymerization was monitored by means of size exclus... | ['Antioxidants', 'Carbolines', 'Chromatography, Gel', 'Free Radical Scavengers', 'Hyaluronic Acid', 'Mannitol', 'Molecular Weight', 'Vinca Alkaloids'] | 9,589,399 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D03.383.725.150', 'D03.633.100.473.155', 'D03.633.300.154'], ['E05.196.181.400.250'], ['D27.505.519.217.500'], ['D09.698.373.475'], ['D02.033.800.609', 'D09.853.609'], ['G02.494'], ['D03.132.436.681.827', 'D03.633.100.473.402.681.827', 'D03.633.100.496.5... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Complete clinical and functional recovery following low-dose methotrexate related paraparesis in a patient with compound c.1298A>C AND c.677C>T MTHFR polymorphism: A case report. | RATIONALE: The mechanisms of action of MTX (methotrexate) in the treatment of RA (rheumatoid arthritis) and PsA (psoriatic arthritis) is related to its antifolic activity, due to the high affinity for enzymes that require folate cofactors as dihydrofolate reductase and to the anti-inflammatory activity derivated from t... | ['Adult', 'Antirheumatic Agents', 'Arthritis, Psoriatic', 'Diagnosis, Differential', 'Female', 'Humans', 'Methotrexate', 'Methylenetetrahydrofolate Reductase (NADPH2)', 'Paraparesis', 'Polymorphism, Genetic'] | 30,544,400 | [['M01.060.116'], ['D27.505.954.329'], ['C05.116.900.853.625.800.424', 'C05.550.114.145', 'C05.550.114.865.800.424', 'C17.800.859.675.175'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.733.631.192.500'], ['D08.811.682.662.290', 'D12.776.331.775'], ['C10.597.636.500', 'C23.888.592.643.500... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Experts consensus of dental esthetic photography]. | Clinical photography in esthetic dentistry is an essential skill in clinical practice. It is widely applied clinically in multiple fields related to esthetic dentistry. Society of Esthetic Dentistry of Chinese Stomatological Association established a consensus for clinical photography and standards for images in esthet... | ['China', 'Consensus', 'Esthetics, Dental', 'Humans', 'Oral Medicine', 'Photography, Dental'] | 28,482,439 | [['Z01.252.474.164'], ['F01.829.316.068', 'F02.463.785.373.433'], ['E06.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E06.640', 'H02.163.670'], ['E01.370.350.600.631', 'E05.712.315', 'E06.342.488']] | ['Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Medicalizing versus psychologizing mental illness: what are the implications for help seeking and stigma? A general population study. | PURPOSE: This study contrasts the medicalized conceptualization of mental illness with psychologizing mental illness and examines what the consequences are of adhering to one model versus the other for help seeking and stigma.METHODS: The survey "Stigma in a Global Context-Belgian Mental Health Study" (2009) conducted ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Belgium', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Interviews as Topic', 'Logistic Models', 'Male', 'Mental Disorders', 'Middle Aged', 'Patient Acceptance of Health Care', 'Psychological Distance', 'Social Perception', 'Social Stigma', 'Socioeco... | 23,474,612 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.542.115'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['E05.318.740.500.525', 'E05.318.740.600.800.45... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
ADAM10 is required for SCF-induced mast cell migration. | A Disintegrin and Metalloproteinase (ADAM)-10 plays critical roles in neuronal migration and distribution. Recently, ADAM10 deletion was shown to disrupt myelopoiesis. We found that inducible deletion of ADAM10 using Mx1-driven Cre recombinase for a period of three weeks resulted in mast cell hyperplasia in the skin, i... | ['ADAM Proteins', 'ADAM10 Protein', 'Amyloid Precursor Protein Secretases', 'Animals', 'Cell Movement', 'Cell Proliferation', 'Cells, Cultured', 'Hyperplasia', 'Interleukin-10', 'Mast Cells', 'Membrane Proteins', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Peritoneum', 'RNA Interference', 'RNA, Small Interfering',... | 24,950,026 | [['D08.811.277.656.675.374.102', 'D09.400.430.500', 'D12.776.395.033'], ['D08.811.277.656.675.374.102.250', 'D09.400.430.500.250', 'D12.776.395.033.250'], ['D08.811.277.656.300.032'], ['B01.050'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['C23.550.444'], ['D12.644.276.374.465... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enzyme-linked immunosorbent assay and colloidal gold immunoassay for sulphamethazine residues in edible animal foods: investigation of the effects of the analytical conditions and the sample matrix on assay performance. | To determine sulphamethazine (SMZ) residues in edible animal foods (pig muscle, chicken muscle, egg, fish, milk and liver), a competitive direct enzyme-linked immunosorbent assay (ELISA) and a colloidal gold immunoassay were established. The limits of detection of the ELISA and the colloidal gold immunoassay were 0.02 ... | ['Animals', 'Chromatography, High Pressure Liquid', 'Eggs', 'Enzyme-Linked Immunosorbent Assay', 'Fishes', 'Food Analysis', 'Gold Colloid', 'Hydrogen-Ion Concentration', 'Meat', 'Milk', 'Molecular Structure', 'Osmolar Concentration', 'Sensitivity and Specificity', 'Sulfamethazine'] | 18,213,472 | [['B01.050'], ['E05.196.181.400.300'], ['G07.203.300.470', 'J02.500.470'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.493'], ['E05.362', 'J01.576.423.850.100'], ['D01.379.400'], ['G02.300'], ['G07.203.300.600', 'J02.500.600'], [... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Pyrolysis characteristics and kinetics of Arundo donax using thermogravimetric analysis. | The increase of the price of fossil means, as well as their programmed disappearing, contributed to increase among appliances based on biomass and energy crops. The thermal behavior of Arundo donax by thermogravimetric analysis was studied under inert atmosphere at heating rates ranging from 5 to 20 degrees C min(-1) f... | ['Carbon Dioxide', 'Carbon Monoxide', 'Computer Simulation', 'Kinetics', 'Organic Chemicals', 'Poaceae', 'Polysaccharides', 'Temperature', 'Thermogravimetry', 'Volatilization', 'Waste Disposal, Fluid'] | 19,362,825 | [['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['L01.224.160'], ['G01.374.661', 'G02.111.490'], ['D02'], ['B01.650.940.800.575.912.250.822'], ['D09.698'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710... | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Curcumin targets the TFEB-lysosome pathway for induction of autophagy. | Curcumin is a hydrophobic polyphenol derived from the herb Curcumalonga and its wide spectrum of pharmacological activities has been widely studied. It has been reported that Curcumin can induce autophagy through inhibition of the Akt-mTOR pathway. However, the effect of Curcumin on lysosome remains largely elusive. In... | ['Animals', 'Antineoplastic Agents, Phytogenic', 'Autophagy', 'Basic Helix-Loop-Helix Leucine Zipper Transcription Factors', 'Cell Line', 'Cell Survival', 'Curcumin', 'Fibroblasts', 'Gene Knockout Techniques', 'HCT116 Cells', 'Humans', 'Lysosomes', 'Mice', 'Protein Binding', 'Signal Transduction', 'TOR Serine-Threonine... | 27,689,333 | [['B01.050'], ['D27.505.954.248.179'], ['G04.011'], ['D12.776.260.103.500', 'D12.776.260.108.092', 'D12.776.930.125.500', 'D12.776.930.127.092'], ['A11.251.210'], ['G04.346'], ['D02.455.326.146.485.222.222', 'D02.455.426.559.389.657.166.200', 'D02.455.426.559.694.222'], ['A11.329.228'], ['E05.393.335.750'], ['A11.251.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A literature analysis of prognostic factors for response and quality of response of patients with renal cell carcinoma to interleukin-2-based therapy. | OBJECTIVE: To characterize prognostic factors for response of advanced renal cell carcinoma to interleukin-2-based regimens.PATIENTS AND METHODS: Data compiled from 80 published series were examined for associations between patient characteristics and outcomes.RESULTS: Response rates were highest in trials utilizing in... | ['Adult', 'Age Factors', 'Aged', 'Antineoplastic Agents', 'Carcinoma, Renal Cell', 'Combined Modality Therapy', 'Disease-Free Survival', 'Female', 'Humans', 'Immunologic Factors', 'Immunotherapy, Adoptive', 'Interferons', 'Interleukin-2', 'Kidney Neoplasms', 'Killer Cells, Lymphokine-Activated', 'Male', 'Middle Aged', ... | 11,528,247 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['D27.505.954.248'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['E02.186'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Potyviral NIa proteinase, a proteinase with novel deoxyribonuclease activity. | The NIa proteinase from pepper vein banding virus (PVBV) is a sequence-specific proteinase required for processing of viral polyprotein in the cytoplasm. It accumulates in the nucleus of the infected plant cell and forms inclusion bodies. The function of this protein in the nucleus is not clear. The purified recombinan... | ['Aspartic Acid', 'Cell Nucleus', 'Cysteine', 'Cytoplasm', 'DNA', 'DNA Mutational Analysis', 'Deoxyribonucleases', 'Dose-Response Relationship, Drug', 'Electrophoresis, Polyacrylamide Gel', 'Endopeptidases', 'Escherichia coli', 'Glutathione Transferase', 'Green Fluorescent Proteins', 'Histidine', 'Hydrogen-Ion Concentr... | 15,163,663 | [['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['A11.284.430.214'], ['D13.444.308'], ['E05.393.760.700.300'], ['D08.811.277.352.335'], ['G07.690.773.875', 'G07.690.936.500'], ['... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Partnership in midwifery care in New Zealand. | OBJECTIVE: to examine whether equal power is essential to the perceptions of partnership in midwifery practice and to propose an alternative model of how power might best be shared.DESIGN: a cross-sectional design was employed using the predominant methods of interview, questionnaires and thinking aloud tape recordings... | ['Adult', 'Anecdotes as Topic', 'Clinical Competence', 'Cross-Sectional Studies', 'Delivery, Obstetric', 'Female', 'Humans', 'Middle Aged', 'Midwifery', 'Models, Nursing', 'New Zealand', 'Nurse Midwives', "Nurse's Role", 'Nurse-Patient Relations', 'Nursing Methodology Research', 'Outcome and Process Assessment, Health ... | 15,020,023 | [['M01.060.116'], ['K01.517.067'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E04.520.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['H02.478.676.416'], ['E05.599.645'], ['Z01.639.760.747', 'Z01.678.1... | ['Named Groups [M]', 'Humanities [K]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Phenomena and Proce... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Perceptions of the impact of a large-scale collaborative improvement programme: experience in the UK Safer Patients Initiative. | RATIONALE AND AIMS: In several countries, collaborative improvement programmes involving multiple health care organizations have been developed to address the issue of patient safety and reliability of care at an organization-wide level. In the UK, the Health Foundation's Safer Patients Initiative (SPI) was developed t... | ['Cooperative Behavior', 'Health Care Surveys', 'Hospitals, Public', 'Humans', 'Interviews as Topic', 'Medical Errors', 'Program Evaluation', 'Quality Assurance, Health Care', 'Retrospective Studies', 'Safety Management', 'United Kingdom'] | 19,522,907 | [['F01.145.813.115'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['N02.278.421.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['N02.421.450'], ['E05.337.82... | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Assessment of Automated Identification of Phases in Videos of Cataract Surgery Using Machine Learning and Deep Learning Techniques. | Importance: Competence in cataract surgery is a public health necessity, and videos of cataract surgery are routinely available to educators and trainees but currently are of limited use in training. Machine learning and deep learning techniques can yield tools that efficiently segment videos of cataract surgery into c... | ['Algorithms', 'Cataract', 'Cataract Extraction', 'Cross-Sectional Studies', 'Deep Learning', 'Humans', 'Image Processing, Computer-Assisted', 'Machine Learning', 'Neural Networks, Computer', 'Observational Studies as Topic', 'Retrospective Studies', 'Sensitivity and Specificity', 'Video Recording'] | 30,951,163 | [['G17.035', 'L01.224.050'], ['C11.510.245'], ['E04.540.825.249'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G17.035.250.500.250', 'G17.485.500', 'L01.224.050.375.530.250', 'L01.224.050.375.605.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['G17.035.250.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Sinulariolide Inhibits Gastric Cancer Cell Migration and Invasion through Downregulation of the EMT Process and Suppression of FAK/PI3K/AKT/mTOR and MAPKs Signaling Pathways. | Cancer metastasis is the main cause of death in cancer patients; however, there is currently no effective method to predict and prevent metastasis of gastric cancer. Therefore, gaining an understanding of the molecular mechanism of tumor metastasis is important for the development of new drugs and improving the surviva... | ['Animals', 'Cell Movement', 'Diterpenes', 'Down-Regulation', 'Focal Adhesion Kinase 1', 'Humans', 'MAP Kinase Signaling System', 'Neoplasm Metastasis', 'Phosphatidylinositol 3-Kinases', 'Proto-Oncogene Proteins c-akt', 'Signal Transduction', 'Stomach Neoplasms', 'TOR Serine-Threonine Kinases', 'Tissue Inhibitor of Met... | 31,783,709 | [['B01.050'], ['G04.198', 'G07.568.500.180'], ['D02.455.849.291'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D08.811.913.696.620.682.725.049.500', 'D12.776.744.493'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['C04.697.650', 'C23.550.727.650'], ['D08.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of fluoxetine and imipramine on the pharmacokinetics and tolerability of the antipsychotic quetiapine. | The effects of fluoxetine and imipramine on the pharmacokinetics and nonpsychiatric side effect profile of quetiapine fumarate were investigated in 26 patients with schizophrenia, schizoaffective disorder, or bipolar disorder in a multicenter, two-period, multiple-dose, open-label, randomized trial. Over a 1- to 2-week... | ['Adolescent', 'Adult', 'Adverse Drug Reaction Reporting Systems', 'Antipsychotic Agents', 'Bipolar Disorder', 'Dibenzothiazepines', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Drug Therapy, Combination', 'Female', 'Fluoxetine', 'Humans', 'Imipramine', 'Male', 'Metabolic Clearance Rate', 'Middle Aged', 'P... | 11,910,263 | [['M01.060.057'], ['M01.060.116'], ['E05.337.800.120', 'N02.421.668.320.120'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F03.084.500'], ['D02.886.680.702.500', 'D03.633.300.276'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['E02.319.310'], ['D02.092.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Traumatic pulmonary pseudocyst. Report of twelve cases. | Twelve cases of traumatic pulmonary pseudocyst were seen between January 1966 and July 1987 at Saiseikai Kanagawaken Hospital. The cause of the traumatic pulmonary pseudocyst was closed blunt chest trauma in all patients. For the first few days after the injury, computed tomographic scan was more useful in diagnosis th... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Cysts', 'Humans', 'Lung Diseases', 'Male', 'Prognosis', 'Thoracic Injuries', 'Tomography, X-Ray Computed', 'Wounds, Nonpenetrating'] | 2,915,566 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['C04.182', 'C23.300.306'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381'], ['E01.789'], ['C26.891'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.8... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Eosinophilic gastroenteritis]. | PURPOSE: Eosinophilic gastroenteritis is a rare and heterogeneous disorder characterized by eosinophilic infiltration of one or more layers of the gastrointestinal tract. Although it can involve any part of the gastrointestinal tract, the stomach and the proximal small bowel are the most common sites of involvement. Cl... | ['Adolescent', 'Adult', 'Enteritis', 'Eosinophilia', 'Female', 'Gastritis', 'Humans', 'Intestine, Small', 'Male', 'Middle Aged', 'Retrospective Studies', 'Serologic Tests', 'Stomach', 'Ultrasonography'] | 22,652,278 | [['M01.060.057'], ['M01.060.116'], ['C06.405.205.462', 'C06.405.469.326'], ['C15.378.553.231'], ['C06.405.205.697', 'C06.405.748.398'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.71... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular characterization of human coronaviruses and their circulation dynamics in Kenya, 2009-2012. | BACKGROUND: Human Coronaviruses (HCoV) are a common cause of respiratory illnesses and are responsible for considerable morbidity and hospitalization across all age groups especially in individuals with compromised immunity. There are six known species of HCoV: HCoV-229E, HCoV-NL63, HCoV-HKU1, HCoV-OC43, MERS-CoV and S... | ['Coronavirus', 'Coronavirus Infections', 'Genes, pol', 'History, 21st Century', 'Humans', 'Kenya', 'Phylogeny', 'Population Surveillance', 'Prevalence', 'RNA, Viral'] | 26,833,249 | [['B04.820.578.500.540.150'], ['C01.925.782.600.550.200'], ['G05.360.340.024.340.364.875.667', 'G05.360.340.358.024.875.667', 'G05.360.340.358.840.500.667'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.058.290.120.400'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.318.308.980.438.70... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Humanities [K]', 'Geographicals [Z]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Mediation and modulation by eicosanoids of responses of spinal dorsal horn neurons to glutamate and substance P receptor agonists: results with indomethacin in the rat in vivo. | In view of the widespread use of non-steroidal anti-inflammatory drugs for treatment of inflammatory pain, we determined the effects of the non-steroidal anti-inflammatory drug, indomethacin, on dorsal horn neurons in the rat spinal cord in vivo. At 2.0-12.0 mg/kg (i.v.), indomethacin depressed the responses of spinal ... | ['Analgesics', 'Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Calcium Signaling', 'Cyclooxygenase Inhibitors', 'Eicosanoids', 'Excitatory Amino Acid Agonists', 'Glutamic Acid', 'Indomethacin', 'Iontophoresis', 'Male', 'N-Methylaspartate', 'Neurons, Afferent', 'Quisqualic Acid', 'Rats', 'Rats, Sprague-Dawley', '... | 10,473,275 | [['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['D27.505.519.389.310', 'D27.505.696.663.850.014.040.500.500', 'D27.505.954.158.030.500', 'D27.505.954.329.0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modifiable risk factors remain significant causes of medium term mortality after first time Coronary artery bypass grafting. | BACKGROUND: Whilst there is much current data on early outcomes after Coronary artery bypass grafting(CABG), there is relatively little data on medium term outcomes in the current era. The purpose of this study is to present a single surgeon series comprising of all first time CABG patients operated on with the techniq... | ['Aged', 'Comorbidity', 'Coronary Artery Bypass', 'Coronary Artery Disease', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Prospective Studies', 'Risk Factors', 'Stroke Volume', 'Survival Analysis'] | 18,053,186 | [['M01.060.116.100'], ['N05.715.350.225', 'N06.850.490.687'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.800.650', 'N05.715.360.325.700.6... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Exogenous BDNF rescues rat spiral ganglion neurons in vivo. | OBJECTIVE: To determine if exogenous neurotrophins can prevent spiral ganglion neuron degeneration in the rat cochlea.BACKGROUND: The loss of hair cells resulting in sensorineural hearing loss also leads to the secondary degeneration of spiral ganglion neurons. The effectiveness of cochlear implantation in patients wit... | ['Animals', 'Brain-Derived Neurotrophic Factor', 'Cell Survival', 'Deafness', 'Nerve Degeneration', 'Rats', 'Rats, Wistar', 'Spiral Ganglion', 'Treatment Outcome'] | 16,151,360 | [['B01.050'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['G04.346'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['C23.550.737'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['A08.340... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of homogenizing methods on accuracy and precision of equine strongylid egg counts. | Recommendations for control of equine strongylid parasites are based on regular determination of fecal egg counts to identify high strongylid shedders and to evaluate treatment efficacy. The McMaster technique has long been used as the standard egg counting technique in equine veterinary practice in most parts of the w... | ['Animals', 'Feces', 'Horse Diseases', 'Horses', 'Parasite Egg Count', 'Strongylida', 'Strongylida Infections'] | 30,253,857 | [['B01.050'], ['A12.459'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['E01.370.225.932.600', 'E05.200.932.600'], ['B01.050.500.500.294.400.968'], ['C01.610.335.508.700.775']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of dry chilling on the genetic diversity of Escherichia coli on beef carcasses and on the survival of E. coli and E. coli O157. | The objective of this study was to examine the effect of dry chilling on the genetic diversity of naturally occurring Escherichia coli on beef carcasses, and to examine whether two populations of E. coli recovered from carcasses during chilling and E. coli O157 differed in their response to desiccation. Isolates of E. ... | ['Animals', 'Cattle', 'Cold Temperature', 'Colony Count, Microbial', 'Desiccation', 'Escherichia coli O157', 'Food Microbiology', 'Food Safety', 'Genetic Variation', 'Genotype', 'Minisatellite Repeats', 'Red Meat', 'Stainless Steel', 'Stress, Physiological'] | 28,068,589 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['E01.370.225.875.220', 'E05.200.875.220'], ['E05.196.335', 'G02.176'], ['B03.440.450.425.325.300.800.250.500', 'B03.660.250.150... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Joint appointees' experiences within a school of nursing and midwifery. | This study evaluated the experiences of joint appointees within a school of nursing and midwifery. The nature of joint appointments has evolved, particularly since nurse education moved from the NHS into higher education institutions. Anecdotal evidence suggests that joint appointments are viewed as a bridge between cl... | ['Administrative Personnel', 'Midwifery', 'Organizational Culture', 'Organizational Objectives', 'Schools, Nursing', 'Staff Development', 'United Kingdom', 'Workforce'] | 19,057,502 | [['M01.526.070'], ['H02.478.676.416'], ['N04.452.606'], ['N04.452.615'], ['I02.783.495.623'], ['I02.574.700', 'N04.452.677.822'], ['Z01.542.363'], ['N04.452.525']] | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Constrained evolution of a quantitative character by pleiotropic mutation. | The long-term response to directional selection and its selection limit are derived for a quantitative character that is controlled by pleiotropic mutations with direct deleterious effect on fitness. Directional selection is assumed to be weaker than the selection acting directly on mutations via deleterious effects (p... | ['Animals', 'Biological Evolution', 'Drosophila', 'Ecosystem', 'Japan', 'Models, Statistical', 'Mutation'] | 16,054,182 | [['B01.050'], ['G05.045', 'G16.075'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['G16.500.275.157', 'N06.230.124'], ['Z01.252.474.463', 'Z01.639.595'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['G05.365.590']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Pouchitis, similar to active ulcerative colitis, is associated with impaired butyrate oxidation by intestinal mucosa. | BACKGROUND: Healthy colonic mucosa uses butyrate as the major energy source. In ulcerative colitis (UC) butyrate oxidation has been shown to be disturbed, but it remains unclear whether this is a primary defect. The aim of this study was to measure mucosal butyrate oxidation in UC (involved and noninvolved colon) and i... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers', 'Biopsy', 'Butyrates', 'Colitis, Ulcerative', 'Colon', 'Colonoscopy', 'Disease Progression', 'Female', 'Humans', 'Ileum', 'Intestinal Mucosa', 'Male', 'Middle Aged', 'Oxidation-Reduction', 'Pouchitis', 'Prognosis', 'Severity of Illness Index', 'Young Ad... | 18,942,762 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D02.241.081.114', 'D10.251.400.143'], ['C06.405.205.265.231', 'C06.405.205.731.24... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
F-Protein, a myofibrillar protein interacting with myosin. | F-Protein has an amino acid composition distinctively different from those of myofibriller proteins so far reported to be of similar chain weight: M-protein component II, alpha-actinin, and AMP deaminase. Its molecular weight was estimated to be 121,000 by sedimentation equilibrium in 0.3 M KCl, 10 mM potassium phospha... | ['Amino Acids', 'Animals', 'Carrier Proteins', 'Molecular Weight', 'Muscle Proteins', 'Muscles', 'Myosins', 'Protein Binding', 'Proteins', 'Rabbits'] | 6,893,043 | [['D12.125'], ['B01.050'], ['D12.776.157'], ['G02.494'], ['D12.776.210.500'], ['A02.633', 'A10.690'], ['D05.750.078.730.475', 'D08.811.277.040.025.193.750', 'D12.776.210.500.600', 'D12.776.220.525.475'], ['G02.111.679', 'G03.808'], ['D12.776'], ['B01.050.150.900.649.313.968.700']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Coronary artery disease: diagnostic approach in 2013]. | Coronary disease can lead to very serious complications which sometimes may have dramatic consequences on the quality of life of our patients. In addition, it can also have numerous social repercussions including a significant increase in the health budget costs. Systematic evaluation adapted to each patient is crucial... | ['Coronary Artery Disease', 'Echocardiography, Stress', 'Exercise Test', 'Humans', 'Magnetic Resonance Imaging', 'Myocardial Perfusion Imaging', 'Positron-Emission Tomography', 'Quality of Life', 'Risk Factors', 'Tomography, X-Ray Computed'] | 23,534,111 | [['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E01.370.350.130.750.228', 'E01.370.350.850.220.228', 'E01.370.370.380.220.228'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E01.370.350.130.875', 'E01... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Peritoneal washing cytology in women: diagnostic pitfalls and clues for correct diagnosis. | The significance of peritoneal washing cytology in the management of patients with gynecologic cancer is well established. Its microscopic evaluation, however, is not always straightforward. Previous studies have identified some of the conditions that may result in misinterpretation of cytologic results. This report re... | ['Ascitic Fluid', 'Carcinoma', 'Diagnosis, Differential', 'Endometriosis', 'Female', 'Genital Neoplasms, Female', 'Humans', 'Peritoneal Lavage', 'Pregnancy', 'Pregnancy Complications, Neoplastic'] | 1,468,343 | [['A12.207.119'], ['C04.557.470.200'], ['E01.171'], ['C13.351.500.163'], ['C04.588.945.418', 'C13.351.937.418'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.927.705'], ['G08.686.784.769'], ['C04.850', 'C13.703.720']] | ['Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The audiovisual structure of onomatopoeias: An intrusion of real-world physics in lexical creation. | Sound-symbolic word classes are found in different cultures and languages worldwide. These words are continuously produced to code complex information about events. Here we explore the capacity of creative language to transport complex multisensory information in a controlled experiment, where our participants improvis... | ['Adult', 'Auditory Perception', 'Female', 'Humans', 'Language', 'Male', 'Middle Aged', 'Models, Theoretical', 'Phonetics', 'Physics', 'Sound', 'Speech Perception', 'Visual Perception', 'Voice', 'Young Adult'] | 29,561,853 | [['M01.060.116'], ['F02.463.593.071', 'G07.888.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['M01.060.116.630'], ['E05.599'], ['L01.559.598.518'], ['H01.671'], ['G01.750.770.776'], ['F02.463.593.071.875', 'G07.888.125.875'], ['F02.463.593.932'], ['G09.772.925'], ['M01.060.116.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
Alternative splicing of the antitrypsin gene in the silkworm, Bombyx mori. | Alternative splicing plays an important role in expanding protein diversity. In the present study, different splice variants of the antitrypsin gene (sw-AT) in the silkworm were identified by bioinformatics analyses using expressed sequence tags and genomic information. Four splice variants were obtained by RT-PCR with... | ['Age Factors', 'Alternative Splicing', 'Amino Acid Sequence', 'Animals', 'Bombyx', 'Computational Biology', 'DNA Primers', 'Exons', 'Expressed Sequence Tags', 'Genes, Insect', 'Molecular Sequence Data', 'Organ Specificity', 'Protein Isoforms', 'Reverse Transcriptase Polymerase Chain Reaction', 'Starvation', 'Stress, P... | 21,104,446 | [['N05.715.350.075', 'N06.850.490.250'], ['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.500.131.617.720.500.500.937.650.100'], ['H01.158.273.180', 'L01.313.124'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.360.... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Primary aldosteronism with aldosterone-producing adrenal adenoma in a pregnant woman. | A 30-year-old pregnant woman complained of muscle weakness at 29 weeks' gestation. She was hypertensive with severe hypokalemia. Lower plasma renin activity and higher aldosterone level than the normal values in pregnancy suggested primary aldosteronism. A cesarean delivery was performed at 31 weeks' gestation because ... | ['Adrenal Cortex Neoplasms', 'Adrenalectomy', 'Adrenocortical Adenoma', 'Adult', 'Aldosterone', 'Cesarean Section', 'Female', 'Follow-Up Studies', 'Humans', 'Hyperaldosteronism', 'Laparoscopy', 'Pregnancy', 'Pregnancy Complications, Neoplastic', 'Renin'] | 10,052,740 | [['C04.588.322.078.265', 'C19.053.098.265', 'C19.053.347.500', 'C19.344.078.265'], ['E04.270.115'], ['C04.588.322.078.265.500', 'C19.053.098.265.500', 'C19.053.347.500.500', 'C19.344.078.265.500'], ['M01.060.116'], ['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['E04.520.252.500'], ['E05.318.372.500.750.24... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Genetic imbalance and human papillomavirus states in vulvar squamous cell carcinomas. | PURPOSE OF INVESTIGATION: Vulvar squamous cell carcinoma (VSCC) is a disease of significant clinical importance, which arises in the presence or absence of human papillomavirus (HPV).METHODS: We used comparative genomic hybridization (CGH) to document non-random chromosomal gains and losses with HPV positive and negati... | ['Base Sequence', 'Carcinoma, Squamous Cell', 'DNA Primers', 'Female', 'Genomic Instability', 'Humans', 'Karyotyping', 'Nucleic Acid Hybridization', 'Papillomaviridae', 'Vulvar Neoplasms'] | 18,179,133 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['C23.550.362', 'G05.365.590.335', 'G05.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Intravenous hyperalimentation as nutritional support for the cancer patient--an update. | Debilitating cancer cachexia is multifactorial, but many of the etiologies and most of the resulting effects are similar to those seen in malnourished patients without cancer. From the work in human beings and experimental animals, nutritional support of the tumor-bearing host can replenish lean body mass, visceral pro... | ['Adenocarcinoma', 'Animals', 'Breast Neoplasms', 'Cachexia', 'Energy Intake', 'Growth', 'Humans', 'Male', 'Mice', 'Mice, Inbred Strains', 'Neoplasms', 'Nutrition Disorders', 'Parenteral Nutrition, Total', 'Rats', 'Rats, Inbred Strains', 'Rodentia', 'Sarcoma'] | 3,935,874 | [['C04.557.470.200.025'], ['B01.050'], ['C04.588.180', 'C17.800.090.500'], ['C23.888.144.243.963.500.500'], ['G07.203.650.240.340'], ['G07.345.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'], ... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical outcomes and patterns of failure in pineoblastoma: a 30-year, single-institution retrospective review. | OBJECTIVE: To update outcomes and assess prognostic factors in the modern, multimodality treatment of patients with pineoblastoma.METHODS: The medical records of patients with pineoblastoma evaluated at the M.D. Anderson Cancer Center between 1982 and 2012 were reviewed retrospectively.RESULTS: Thirty-one patients with... | ['Adolescent', 'Adult', 'Brain Neoplasms', 'Child', 'Child, Preschool', 'Combined Modality Therapy', 'Female', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Pineal Gland', 'Pinealoma', 'Retrospective Studies', 'Survival Analysis', 'Treatment Failure', 'Treatment Outcome', 'Young Adult'] | 25,045,788 | [['M01.060.057'], ['M01.060.116'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['M01.060.406'], ['M01.060.406.448'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['A06.300.635', 'A06.688.733', 'A08.186.211.180.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Increase in predation risk and trophic level induced by nocturnal visits of piscivorous fishes in a temperate seagrass bed. | The majority of surveys on food webs of aquatic ecosystems have been conducted during the day owning to difficulties in sampling animals at night. In this study, to examine diurnal changes in predator-prey interactions in a temperate seagrass Zostera marina bed, a quantitative day/night survey of fish, the dominant ani... | ['Animals', 'Ecosystem', 'Environment', 'Fishes', 'Food Chain', 'Predatory Behavior'] | 28,634,330 | [['B01.050'], ['G16.500.275.157', 'N06.230.124'], ['G16.500.275', 'N06.230'], ['B01.050.150.900.493'], ['G16.500.275.157.250', 'N06.230.124.250'], ['F01.145.113.111.600', 'F01.145.113.252.520']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Mood and smoking in schizophrenia. | There have been few investigations into the relationship of smoking to the presentation of anxiety and depression in clients with a primary diagnosis of schizophrenia. Using a survey design, the current study sought to determine if there was a significant difference between smoking and non-smoking clients in this clini... | ['Adult', 'Affect', 'Anxiety', 'Depression', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nicotine', 'Schizophrenic Psychology', 'Smoking'] | 18,844,797 | [['M01.060.116'], ['F01.470.047'], ['F01.470.132'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D03.132.760.570', 'D03.383.725.518'], ['F04.824'], ['F01.145.805']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Arsenic speciation in tissues of the hyperaccumulator P. calomelanos var. austroamericana using X-ray absorption spectroscopy. | The fate and chemical speciation of arsenic (As) during uptake, translocation, and storage by the As hyperaccumulating fern Pityrogramma calomelanos var. austroamericana (Pteridaceae) were examined using inductively coupled plasma-atomic emission spectrometry (ICP-AES) and synchrotron-based micro-X-ray absorption near ... | ['Arsenic', 'Ferns', 'Tissue Distribution', 'X-Ray Absorption Spectroscopy'] | 20,459,123 | [['D01.268.513.249'], ['B01.650.940.800.575.912.063'], ['G03.787.917', 'G07.690.725.949'], ['E05.196.867.972']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of ephedrine on the onset time of rocuronium in Thai patients. | UNLABELLED: The aim of this study was to determine the effect of ephedrine on the onset time of rocuronium. The study population was 60 ASA physical status 1 and 2 patients, aged 15-60 years scheduled for elective surgery under general anesthesia at Ramathibodi Hospital. The patients were randomly assigned into 2 group... | ['Adolescent', 'Adult', 'Androstanols', 'Double-Blind Method', 'Ephedrine', 'Female', 'Humans', 'Intubation, Intratracheal', 'Male', 'Middle Aged', 'Reaction Time', 'Rocuronium', 'Thailand', 'Time Factors'] | 15,117,042 | [['M01.060.057'], ['M01.060.116'], ['D04.210.500.054.040'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D02.033.100.624.302', 'D02.033.755.624.302', 'D02.092.063.624.302', 'D02.092.471.683.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.500', 'E02.585.578', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Assessment of a Colonoscopy Triage Sheet for Use in a Province-Wide Population-Based Colorectal Screening Program. | Background and Aims. A colonoscopy triage sheet (CTS) integrating 6 hierarchical scheduling priorities based on indications for screening, surveillance, or symptoms was designed for colonoscopy referral. We compared CTS priority ratings by referring physicians and endoscopists, assessing yields. Methods. Retrospective ... | ['Aged', 'Colonic Polyps', 'Colonoscopy', 'Colorectal Neoplasms', 'Early Detection of Cancer', 'Female', 'Humans', 'Male', 'Mass Screening', 'Middle Aged', 'Multivariate Analysis', 'Quebec', 'Referral and Consultation', 'Reproducibility of Results', 'Retrospective Studies', 'Triage'] | 27,446,841 | [['M01.060.116.100'], ['C23.300.825.411.235'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E01.390.500'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Adolescent sexuality: values, morality and decision making. | The first section of this paper presents a theoretical basis of morality and value formation which provides the background for an examination of adolescent sexual and cognitive development. Data from a study of influences on the sexual decisions of five hundred 13- to 19-year-olds are analyzed in the remainder of the a... | ['Adolescent', 'Contraception Behavior', 'Decision Making', 'Female', 'Gender Identity', 'Humans', 'Male', 'Morals', 'Psychosexual Development', 'Sexual Behavior', 'Social Values'] | 3,434,382 | [['M01.060.057'], ['F01.145.688.500', 'G08.686.784.891.500'], ['F02.463.785.373'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.500', 'K01.752.566'], ['F01.752.747.722', 'F02.739.794.793'], ['F01.145.802'], ['F01.829... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
National mortality rates: the impact of inequality? | Although health is closely associated with income differences within each country there is, at best, only a weak link between national mortality rates and average income among the developed countries. On the other hand, there is evidence of a strong relationship between national mortality rates and the scale of income ... | ['Humans', 'Income', 'Internationality', 'Mortality', 'Poverty', 'Risk Factors', 'Socioeconomic Factors', 'United Kingdom'] | 1,636,827 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.417'], ['I01.615'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.550', 'N06.850.520.308.985.550'], ['I01.880.735.634', 'I01.880.853.996.535', 'N01.824.600'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', '... | ['Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Nuclear envelope impairment is facilitated by the herpes simplex virus 1 Us3 kinase. | Background: Capsids of herpes simplex virus 1 (HSV-1) are assembled in the nucleus, translocated either to the perinuclear space by budding at the inner nuclear membrane acquiring tegument and envelope, or released to the cytosol in a "naked" state via impaired nuclear pores that finally results in impairment of the nu... | ['Capsid', 'Herpes Simplex', 'Herpesvirus 1, Human', 'Humans', 'Nuclear Envelope', 'Protein-Serine-Threonine Kinases', 'Viral Proteins'] | 31,249,678 | [['A21.249.500.250'], ['C01.925.256.466.382', 'C01.925.825.320', 'C17.800.838.790.320'], ['B04.280.382.100.750.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.149.165.630', 'A11.284.149.450.700', 'A11.284.430.106.279.692', 'A11.284.835.514.700'], ['D08.811.913.696.620.682.700'], ['D12.776.964']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exercise Mode Specificity for Preserving Spine and Hip Bone Mineral Density in Prostate Cancer Patients. | PURPOSE: Androgen deprivation therapy (ADT) in men with prostate cancer (PCa) is associated with an array of adverse effects, including reduced bone mineral density (BMD) predisposing patients to increased fracture risk. Our purpose was to examine the effects of targeted exercise modes on BMD in men with PCa undergoing... | ['Androgen Antagonists', 'Antineoplastic Agents, Hormonal', 'Body Mass Index', 'Bone Density', 'Exercise Therapy', 'Hip', 'Humans', 'Male', 'Muscle Strength', 'Muscle, Skeletal', 'Prostatic Neoplasms', 'Resistance Training', 'Spine'] | 30,395,051 | [['D06.347.065', 'D27.505.696.399.450.065'], ['D27.505.954.248.169'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G11.427.100'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['A01.378.610.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Misconceptions regarding hepatitis C in the French public. | BACKGROUND: Knowing the facts and displaying the proper attitudes and behaviors are critical in preventing the spread of infectious diseases. Hepatitis C is a common infection, but the public's understanding of it has not been studied.METHODS: A convenience sample of 431 French adults, ages 18 to 81 years, completed a ... | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Aged', 'Aged, 80 and over', 'Attitude to Health', 'Female', 'France', 'Hepatitis C', 'Humans', 'Male', 'Middle Aged', 'Risk-Taking', 'Surveys and Questionnaires'] | 12,052,019 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.150', 'N05.300.150'], ['Z01.542.286'], ['C01.221.250.750', 'C01.925.440.440', '... | ['Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Probability of gene identity by descent: computation and applications. | Two genes at a given locus are identical by descent (IBD) if both have been inherited from a common ancestor. We present an algorithm for computing the probabilities of all IBD relationships among the genes of pedigree members. We show how to use these probabilities to calculate the probability of any combination of ge... | ['Algorithms', 'Biometry', 'Female', 'Genetic Counseling', 'Genetic Linkage', 'Genotype', 'Humans', 'Male', 'Models, Genetic', 'Pedigree', 'Phenotype', 'Probability'] | 8,086,594 | [['G17.035', 'L01.224.050'], ['E05.318.740.225', 'N06.850.505.200'], ['H01.158.273.343.385.500.384', 'N02.421.308.400'], ['G05.348'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.397'], ['E05.393.673'], ['G05.695'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.60... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Elemental levels in mast cell granules differ in sections from normal and diabetic rats: an X-ray microanalysis study. | Mast cells around the thymus of rats stain red with alcian blue and safranin indicating that the mast cells are probably of the peritoneal (connective tissue) type. After the onset of streptozotocin induced diabetes some cells contain both red and blue granules and blue staining cells may appear. X-ray microanalysis of... | ['Animals', 'Cytoplasmic Granules', 'Diabetes Mellitus, Experimental', 'Electron Probe Microanalysis', 'Elements', 'Male', 'Mast Cells', 'Microscopy, Electron', 'Rats', 'Rats, Inbred Strains', 'Reference Values', 'Thymus Gland'] | 3,368,763 | [['B01.050'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['E01.370.350.515.402.250', 'E05.196.867.800.360', 'E05.595.402.250', 'E05.799.830.360'], ['D01.268'], ['A11.329.427', 'A15.382.652'], ['E01.370.350.515.402', 'E05.595.402'], ['B01.05... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Proposal of a new scale for assessing fatigue in patients with multiple sclerosis]. | Fatigue is a complaint often made by multiple sclerosis patients. Description of the symptom varies from patient to patient. This paper proposes a descriptive and quantitative scale for assessing fatigue in these patients. Eighty patients classified as having Poser's type I multiple sclerosis were asked to respond to a... | ['Adult', 'Fatigue', 'Female', 'Humans', 'Male', 'Middle Aged', 'Multiple Sclerosis', 'Reproducibility of Results', 'Severity of Illness Index', 'Surveys and Questionnaires'] | 8,204,266 | [['M01.060.116'], ['C23.888.369'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.5... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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