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SCIRehab Project series: the social work/case management taxonomy. | CONTEXT: Social work and case management (SW/CM) are integral components of acute inpatient spinal cord injury (SCI) rehabilitation. However, evidence is sparse regarding the impact of SW/CM interventions on outcomes. To advance research on SW/CM clinical practice in SCI rehabilitation, SW/CM providers and researchers ... | ['Case Management', 'Classification', 'Home Care Services', 'Humans', 'Quality Assurance, Health Care', 'Social Work', 'Spinal Cord Injuries'] | 19,810,635 | [['N04.590.233.624.250'], ['L01.100', 'L01.453.245.275'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700', 'N05.700'], ['I01.880.792', 'N02.421.849'], ['C10.228.854.763', 'C10.900.850', 'C26.819']] | ['Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Undergraduate teaching of nuclear medicine in European universities. | This paper provides an overview of the curricula of undergraduate training in nuclear medicine in 77 European medical departments and, for comparison, in nine departments outside Europe. The data show a high level of variation in the number of hours (0-62) devoted to nuclear medicine in the different departments. In mo... | ['Curriculum', 'Data Collection', 'Education, Medical, Undergraduate', 'Europe', 'Nuclear Medicine', 'Radiology', 'Teaching', 'Universities'] | 12,721,769 | [['I02.158'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['I02.358.399.450'], ['Z01.542'], ['H02.403.740.500'], ['H02.403.740'], ['I02.903'], ['I02.783.830', 'J03.832.830']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 |
Chlorotyrosine exerts renal effects and antagonizes renal and gastric responses to atrial natriuretic peptide. | 3-Chloro-L-tyrosine (3CT) is an inhibitor of tyrosine hydroxylase, the rate-limiting enzyme for catecholamine synthesis. In vivo inhibition of tyrosine hydroxylase results in lower catecholamine levels. 3CT (0.5 mg/kg), administered as a bolus i.v. to anesthetized uninephrectomized rats, elicited increases of 72% and 4... | ['Animals', 'Atrial Natriuretic Factor', 'Cerebral Ventricles', 'Diuresis', 'Enzyme Activation', 'Gastric Acid', 'Gastric Mucosa', 'Guanylate Cyclase', 'Kidney', 'Male', 'Natriuresis', 'Potassium', 'Rats', 'Rats, Sprague-Dawley', 'Tyrosine', 'Tyrosine 3-Monooxygenase'] | 7,910,211 | [['B01.050'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['A08.186.211.140'], ['G08.852.179'], ['G02.111.263', 'G03.328'], ['A12.200.307.603'], ['A03.556.875.875.440', 'A10.615.550.291'], ['D08.811.520.650.600', 'D12.644.360.350', 'D12.776.476.350'], ['A05.810.453'], ['G08.852.179.557'], ['D01.268.549.550', 'D01.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subpallial amygdala and nucleus taeniae in birds resemble extended amygdala and medial amygdala in mammals in their expression of markers of regional identity. | Two regions were recently recognized as subpallial amygdaloid nuclei in birds, the nucleus taeniae of the amygdala (TnA) and the newly identified subpallial amygdala (SpA). Here we further confirm these nuclei to be subpallial and amygdaloid and show similarity to specific mammalian subpallial amygdaloid nuclei. By its... | ['Amygdala', 'Animals', 'Cell Adhesion Molecules, Neuronal', 'Chickens', 'Columbidae', 'GPI-Linked Proteins', 'Gene Expression Regulation', 'Glutamate Decarboxylase', 'Immunohistochemistry', 'In Situ Hybridization', 'Isoenzymes', 'Mice', 'Mice, Inbred C57BL', 'Rats', 'Rats, Sprague-Dawley', 'Species Specificity'] | 16,144,611 | [['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['B01.050'], ['D12.776.395.550.200.250', 'D12.776.543.550.200.250', 'D23.050.301.350.250'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['B01.050.150.900.248.165.150'], ['D12.776.395.550.448', 'D12.776.543.484.500', 'D12.776.543.550.418'],... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Individual growth curves and longitudinal growth charts between 0 and 3 years. | From a statistical viewpoint, the construction of longitudinal growth norms involves two classes of problems: (a) the choice of a mathematical function having a few constants as possible, but suitable for describing individual growth process in the growth period of concern; (b) the estimation of the mean growth constan... | ['Child, Preschool', 'Female', 'Growth', 'Humans', 'Infant', 'Infant, Newborn', 'Italy', 'Longitudinal Studies', 'Male', 'Models, Statistical', 'Reference Standards', 'Reference Values'] | 2,801,109 | [['M01.060.406.448'], ['G07.345.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['Z01.542.489'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Epidemiology of dermatofibrosarcoma protuberans in Alberta, Canada, from 1988 to 2007. | BACKGROUND: There have only been a few population-based, epidemiologic studies assessing dermatofibrosarcoma protuberans (DFSP).OBJECTIVE: To assess the epidemiology of DFSP in Alberta, Canada, over a 20-year period.METHODS: A population-based, retrospective analysis of all cases of DFSP in Alberta was conducted using ... | ['Adolescent', 'Adult', 'Age Distribution', 'Alberta', 'Child', 'Child, Preschool', 'Dermatofibrosarcoma', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Incidence', 'Infant', 'Lower Extremity', 'Male', 'Middle Aged', 'Prevalence', 'Retrospective Studies', 'Sex Ratio', 'Skin Neoplasms', 'Torso', 'Upper Extremity', 'Yo... | 22,691,126 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['Z01.107.567.176.064'], ['M01.060.406'], ['M01.060.406.448'], ['C04.557.450.565.590.350.320', 'C04.557.450.795.350.320'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Involvement of Nrf2 and JNK1 in the activation of antioxidant responsive element (ARE) by chemopreventive agent phenethyl isothiocyanate (PEITC). | PURPOSE: Phenethyl isothiocyanate (PEITC) has been of great interest as a promising cancer chemopreventive agent. To better understand its chemopreventive activity, we examined the effect of PEITC on the antioxidant responsive element (ARE), which is an important gene regulatory element of many phase II drug-metabolizi... | ['Anticarcinogenic Agents', 'Antioxidants', 'Chemoprevention', 'DNA-Binding Proteins', 'Enzyme Induction', 'Genes, Reporter', 'HeLa Cells', 'Humans', 'Isothiocyanates', 'Luciferases', 'Mitogen-Activated Protein Kinase 8', 'Mitogen-Activated Protein Kinases', 'NF-E2-Related Factor 2', 'Response Elements', 'Signal Transd... | 14,567,627 | [['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['E02.319.162'], ['D12.776.260'], ['G05.308.320.200'], ['G05.360.340.024.340.435'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aerobic kinetoplastid flagellate Phytomonas does not require heme for viability. | Heme is an iron-coordinated porphyrin that is universally essential as a protein cofactor for fundamental cellular processes, such as electron transport in the respiratory chain, oxidative stress response, or redox reactions in various metabolic pathways. Parasitic kinetoplastid flagellates represent a rare example of ... | ['Crithidia fasciculata', 'Electron Transport', 'Ergosterol', 'Fatty Acids', 'Heme', 'Kinetoplastida', 'Lanosterol', 'Models, Biological', 'Oxidation-Reduction', 'Oxidative Stress', 'Oxygen', 'Phylogeny', 'Porphyrins', 'Sterols', 'Trypanosomatina'] | 22,355,128 | [['B01.268.475.868.110.350'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['D04.210.500.247.222.537'], ['D10.251'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['B01.268.475'], ['D02.455.849.919.383', 'D04.210.500.247.222.222.347.557', 'D0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Spherulitic assembly of peptide nanowires via spontaneous crystallization. | In this work, the hierarchal arrangement of peptide nanowires was achieved via the spontaneous crystallization of peptide molecules. Peptide molecules, which are structural motifs associated with Alzheimer's disease, assembled into one-dimensional nanowires and spontaneously formed two-dimensional peptide spherulites d... | ['Crystallization', 'Nanotechnology', 'Nanowires', 'Peptides', 'Phenylalanine'] | 25,958,606 | [['E05.196.300', 'G02.171'], ['H01.603', 'J01.897.520.600'], ['J01.637.512.925'], ['D12.644'], ['D12.125.072.050.685', 'D12.125.142.666']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Visceral fat is associated with elevation of serum alanine aminotransferase and gamma glutamyltransferase in middle-aged Chinese adults. | BACKGROUND : Elevation of hepatic enzymes is associated with insulin resistance, dyslipidaemia and obesity. However, the factors behind elevation of liver enzymes remain unclear. The aim of this study was to compare the role of abdominal visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) in relation wi... | ['Alanine Transaminase', 'Asian Continental Ancestry Group', 'Biomarkers', 'Cross-Sectional Studies', 'Female', 'Glucose Tolerance Test', 'Humans', 'Insulin Resistance', 'Intra-Abdominal Fat', 'Liver Function Tests', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Obesity', 'Predictive Value of Tests', 'gamma-Glu... | 30,523,069 | [['D08.811.913.477.700.100'], ['M01.686.508.200'], ['D23.101'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['A10.165... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Consequences of in utero caffeine exposure on respiratory output in normoxic and hypoxic conditions and related changes of Fos expression: a study on brainstem-spinal cord preparations isolated from newborn rats. | Several aspects of the central regulation of respiratory control have been investigated on brainstem-spinal cord preparations isolated from newborn rats whose dam was given 0.02% caffeine in water as drinking fluid during the whole period of pregnancy. Analysis of the central respiratory drive estimated by the recordin... | ['Animals', 'Animals, Newborn', 'Brain Stem', 'Caffeine', 'Carbon Dioxide', 'Electrophysiology', 'Female', 'Hypoxia, Brain', 'Immunohistochemistry', 'In Vitro Techniques', 'Medulla Oblongata', 'Pons', 'Pregnancy', 'Proto-Oncogene Proteins c-fos', 'Rats', 'Rats, Sprague-Dawley', 'Respiratory Center', 'Spinal Cord', 'Ute... | 12,538,785 | [['B01.050'], ['B01.050.050.282'], ['A08.186.211.132'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['H01.158.344.528', 'H01.158.782.236'], ['C10.228.140.624', 'C23.888.852.079.797'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512',... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid identification of mitochondrial DNA (mtDNA) mutations in neuromuscular disorders by using surveyor strategy. | Mutations of mitochondrial genome are responsible for respiratory chain defects in numerous patients. We have used a strategy, based on the use of a mismatch-specific DNA endonuclease named " Surveyor Nuclease", for screening the entire mtDNA in a group of 50 patients with neuromuscular features, suggesting a respirato... | ['Adolescent', 'Adult', 'Child, Preschool', 'DNA, Mitochondrial', 'Endonucleases', 'Female', 'Genetic Testing', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Mitochondrial Diseases', 'Neuromuscular Diseases', 'Pedigree'] | 18,078,792 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406.448'], ['D13.444.308.283.225'], ['D08.811.277.352.355'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['C18.452.660'], ['C10.668'], ['E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The amber theory of Lyme arthritis: initial description and clinical implications. | Lyme arthritis differs in many respects from other bacterial causes of arthritis. Based on an observation made for a patient with Lyme arthritis, we propose that the pathogenesis of joint swelling in Lyme arthritis is due to the introduction into the joint space of non-viable spirochetes or more likely spirochetal debr... | ['Anti-Bacterial Agents', 'Biofilms', 'Borrelia burgdorferi', 'Collagen', 'Humans', 'Inflammation', 'Joint Diseases', 'Joints', 'Lyme Disease', 'Models, Biological', 'Models, Theoretical', 'Rheumatology'] | 22,411,576 | [['D27.505.954.122.085'], ['A20.593', 'G06.120'], ['B03.440.425.410.711.193.150.125', 'B03.851.595.193.150.125'], ['D05.750.078.280', 'D12.776.860.300.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['C05.550'], ['A02.835.583'], ['C01.150.252.400.536', 'C01.150.252.400.794.352.250', 'C01.920.93... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Management of voiding dysfunction in elderly patients: prognosis 1 year after discharge from hospital]. | We investigated how 293 elderly patients who had been successfully treated to be free of catheters or diapers managed to urinate one year after their discharge from our hospital. Of 192 patients who returned to their own home 154 (80%) had good activities in daily life (ADL), and of 101 who moved to a nursing home or o... | ['Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Chi-Square Distribution', 'Female', 'Home Care Services', 'Humans', 'Incontinence Pads', 'Male', 'Middle Aged', 'Patient Discharge', 'Prognosis', 'Urinary Catheterization', 'Urinary Incontinence', 'Urination Disorders'] | 7,832,082 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.325.068.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The histopathology of polymicrogyria: a series of 71 brain autopsy studies. | AIM: Polymicrogyria (PMG) is one of the most common forms of cortical malformation yet the mechanism of its development remains unknown. This study describes the histopathological aspects of PMG in a large series including a significant proportion of fetal cases.METHOD: We have reviewed the neuropathology and medical r... | ['Adolescent', 'Adult', 'Autopsy', 'Brain', 'Child', 'Child, Preschool', 'Fetus', 'Humans', 'Infant', 'Infant, Newborn', 'Polymicrogyria', 'Young Adult'] | 26,179,148 | [['M01.060.057'], ['M01.060.116'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['A08.186.211'], ['M01.060.406'], ['M01.060.406.448'], ['A16.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C10.500.507.500.500', 'C16.131.666.507.500.500'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[Repair of posttraumatic hand defects in children]. | The experience with the use of a method of distraction for reconstruction of 98 digits in 37 patients with amputation defects has been summarized. Lengthening of the digits by 3-7 cm was achieved. This permitted to improve considerably the function and cosmetic appearance of a damaged hand. | ['Adolescent', 'Amputation, Traumatic', 'Bone Lengthening', 'Child', 'Child, Preschool', 'Female', 'Finger Injuries', 'Hand Deformities, Acquired', 'Humans', 'Male', 'Surgery, Plastic'] | 8,301,957 | [['M01.060.057'], ['C26.062'], ['E04.555.120'], ['M01.060.406'], ['M01.060.406.448'], ['C26.448.429'], ['C05.390.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.810.788']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of active immunization against gonadotropin-releasing hormone on the ultrastructure of the rat ventral prostate. | To evaluate the effects of active immunization against gonadotropin-releasing hormone (GnRH) on the ultrastructure of the rat ventral prostate, male Sprague-Dawley rats received three consecutive intramuscular injections of 10 micrograms/100 g body weight (D-Lys6)-GnRH-diphtheria toxoid conjugate (GnRH-DT vaccine). Fol... | ['Animals', 'Diphtheria Toxoid', 'Gonadotropin-Releasing Hormone', 'Male', 'Microscopy, Electron', 'Prostate', 'Rats', 'Rats, Sprague-Dawley', 'Vaccination', 'Vaccines, Conjugate'] | 7,974,913 | [['B01.050'], ['D20.215.894.691.263'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['E01.370.350.515.402', 'E05.595.402'], ['A05.360.444.575', 'A10.336.707'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Extramedullary haematopoiesis: report of two cases]. | Extramedullary haematopoiesis is a physiologic response to chronic anaemia, commonly observed in various haematological disorders. This phenomenon is habitually asymptomatic but it may induce compression of adjacent organs such as the spinal cord. We present the cases of two patients suffering from chronic anaemia, who... | ['Abdomen', 'Adolescent', 'Adult', 'Anemia', 'Hematologic Diseases', 'Hematopoiesis, Extramedullary', 'Humans', 'Male', 'Radiography, Thoracic', 'Splenectomy', 'Thalassemia', 'Tomography, X-Ray Computed'] | 17,714,971 | [['A01.923.047'], ['M01.060.057'], ['M01.060.116'], ['C15.378.071'], ['C15.378'], ['G04.152.825.463', 'G09.188.343.463'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.730'], ['E04.726'], ['C15.378.071.141.150.875', 'C15.378.420.826', 'C16.320.070.875', 'C16.320.365.826'], ['E01.370.350.350.810', '... | ['Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Thermal enhancement of ACNU and potentiation of thermochemotherapy with ACNU by hypertonic glucose in the BT4An rat glioma. | Hyperthermia increases the cytotoxicity of the nitrosourea BCNU (carmustine). Glucose given before treatment may further increase the value of thermochemotherapy, presumably by lowering tumour pH through blood flow reduction. The water-soluble ACNU (nimustine) is an alternative to other nitrosoureas in the treatment of... | ['Animals', 'Brain Neoplasms', 'Carmustine', 'Combined Modality Therapy', 'Drug Screening Assays, Antitumor', 'Drug Synergism', 'Glioma', 'Glucose', 'Hydrogen-Ion Concentration', 'Hyperthermia, Induced', 'Hypertonic Solutions', 'Neoplasm Transplantation', 'Nimustine', 'Rats', 'Rats, Inbred Strains', 'Retinal Diseases',... | 1,895,166 | [['B01.050'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['D02.065.950.594.247', 'D02.654.692.247'], ['E02.186'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['G07.690.773.968.477'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['D0... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cisplatin sensitivity is enhanced in non-small cell lung cancer cells by regulating epithelial-mesenchymal transition through inhibition of eukaryotic translation initiation factor 5A2. | BACKGROUND: Epithelial-mesenchymal transition (EMT) has been believed to be related with chemotherapy resistance in non-small cell lung cancer (NSCLC). Recent studies have suggested eIF5A-2 may function as a proliferation-related oncogene in tumorigenic processes.METHODS: We used cell viability assays, western blotting... | ['Antineoplastic Agents', 'Cadherins', 'Carcinoma, Non-Small-Cell Lung', 'Cell Line, Tumor', 'Cell Movement', 'Cell Survival', 'Cisplatin', 'Drug Resistance, Neoplasm', 'Drug Synergism', 'Enzyme Inhibitors', 'Epithelial-Mesenchymal Transition', 'Gene Silencing', 'Guanine', 'Humans', 'Inhibitory Concentration 50', 'Lung... | 25,380,840 | [['D27.505.954.248'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.346'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
What is being measured, and by whom? Facilitation of communication on technical measures amongst competent authorities in the implementation of the European Union Broiler Directive (2007/43/EC). | The European Union (EU) Broiler Directive (2007/43/EC) is unique amongst current EU Directives, which address animal welfare, in that it uses outcome data collected at abattoirs and on farm to monitor on-farm broiler welfare and vary the maximum permitted stocking density on farm. In this study, we describe how, by bri... | ['Abattoirs', 'Animal Husbandry', 'Animal Welfare', 'Animals', 'Chickens', 'European Union', 'Food Inspection', 'Humans', 'Poultry Diseases', 'Poultry Products'] | 26,278,785 | [['J01.576.423.200.700.100', 'J03.540.020'], ['J01.040.090'], ['I01.880.604.100'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['I01.615.500.475'], ['J01.576.423.850.730.500.500', 'N06.850.601.500.500', 'N06.850.780.200.800.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C22.1... | ['Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
Cost-effective multiplication of the entomopathogenic fungus Nomuraea rileyi (F) Samson. | Cost-effective and rapid multiplication of Nomuraea rileyi is reported. The spore yields in semi-synthetic media were comparable or significantly higher to the standard medium. Maltose and peptone, carbon and nitrogen sources could be effectively replaced with 2% barley extract and 1% soybean extract respectively. Howe... | ['Animals', 'Cost-Benefit Analysis', 'Culture Media', 'Hordeum', 'Insecta', 'Mitosporic Fungi', 'Pest Control, Biological', 'Soybeans', 'Spodoptera'] | 11,502,062 | [['B01.050'], ['N03.219.151.125'], ['D27.720.470.305', 'E07.206'], ['B01.650.940.800.575.912.250.822.481'], ['B01.050.500.131.617'], ['B01.300.381'], ['N06.850.780.200.650.650'], ['B01.650.940.800.575.912.250.401.750'], ['B01.050.500.131.617.720.500.500.937.650.700']] | ['Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Humanization in health care: knowledge disseminated in Brazilian nursing literature]. | This qualitative research aims to analyze the scientific production about "humane health care/nursing", understanding what views on humanization have been developing. A bibliographic survey was carried out, covering the period from the end of the 1950's until today, in the periodicals Revista Brasileira de Enfermagem, ... | ['Bibliometrics', 'Brazil', 'Humanism', 'Humans', 'Nursing'] | 15,761,588 | [['L01.178.682.099.325', 'L01.453.183.291'], ['Z01.107.757.176'], ['K01.752.566.479.174', 'N05.350.835'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.478', 'N04.452.758.377']] | ['Information Science [L]', 'Geographicals [Z]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Intracellular Binding Site for a Positive Allosteric Modulator of the Dopamine D1 Receptor. | The binding site for DETQ [2-(2,6-dichlorophenyl)-1-((1S,3R)-3-(hydroxymethyl)-5-(2-hydroxypropan-2-yl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one], a positive allosteric modulator (PAM) of the dopamine D1 receptor, was identified and compared with the binding site for CID 2886111 [N-(6-tert-butyl-3-carbamoyl... | ['Allosteric Regulation', 'Allosteric Site', 'Amino Acids', 'Animals', 'Cell Line', 'Conserved Sequence', 'Dopamine', 'HEK293 Cells', 'Humans', 'Isoquinolines', 'Rats', 'Receptors, Dopamine D1'] | 30,111,649 | [['G02.111.044'], ['G02.111.570.120.147'], ['D12.125'], ['B01.050'], ['A11.251.210'], ['G02.111.570.580'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.531'], ['B01.050.150.900.64... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of a corrugated channel on the retentive properties of an obturator-reinforced composite resin dowel-core system. | A study was conducted to compare the retentive properties of the obturator-reinforced composite resin dowel and core systems with and without corrugated dentin surfaces in the dowel channels. A commercially available tap with a diameter of about 1.4 mm and a thread groove depth of 100 micron was used to accomplish this... | ['Crowns', 'Dental Instruments', 'Dental Materials', 'Dental Stress Analysis', 'Dentin', 'Humans', 'In Vitro Techniques', 'Incisor', 'Post and Core Technique'] | 6,368,804 | [['E06.780.346.250', 'E07.695.190.088'], ['E06.186.501', 'E07.222.501'], ['D25.339', 'D27.720.102.339', 'J01.637.051.339'], ['E06.308'], ['A14.549.167.900.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A14.549.167.860.425'], ['E06.780.346.250.500', 'E07.695.190.088.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Sudden death associated with intravenous injection of toad extract. | A 24-year-old male died suddenly following the intravenous injection of what was believed to be the ring-derivate amphetamine 'ecstasy' (MDMA). Toxicological analyses of the victim's blood and the injected material, however, failed to reveal MDMA, but showed instead low levels of bufotenine, a tryptamine derivative alk... | ['Amphibian Venoms', 'Animals', 'Anura', 'Bufanolides', 'Bufotenin', 'Death, Sudden', 'Forensic Toxicology', 'Hallucinogens', 'Humans', 'Illicit Drugs', 'Injections, Intravenous', 'Male', 'N-Methyl-3,4-methylenedioxyamphetamine', 'Young Adult'] | 19,303,230 | [['D20.888.033', 'D23.946.833.033'], ['B01.050'], ['B01.050.150.900.090.180'], ['D04.210.500.155.580.064'], ['D03.633.100.473.914.237.150', 'D03.633.100.473.914.814.150', 'D20.888.033.163', 'D23.946.833.033.163'], ['C23.550.260.322'], ['H01.158.891.424', 'H02.884.424', 'I01.198.780.968'], ['D27.505.696.388', 'D27.505.9... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
Early Childhood Disadvantage for Sons of Mexican Immigrants: Body Mass Index Across Ages 2-5. | PURPOSE: To distinguish the origins of higher weight status and determine when and why intra- and interracial/ethnic disparities emerge.DESIGN: The study used a longitudinal analysis of the Early Childhood Longitudinal Study-Birth Cohort (ECLS-B).SETTING: The study was conducted in the United States.SUBJECTS: Participa... | ['Body Mass Index', 'Body Weight', 'Child, Preschool', 'Emigrants and Immigrants', 'European Continental Ancestry Group', 'Humans', 'Longitudinal Studies', 'Male', 'Mexican Americans', 'Obesity', 'United States'] | 26,305,614 | [['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406.448'], ['M01.189'], ['M01.686.508.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
An immunohistochemical study on the development of progastricsin-immunoreactive cells in the bovine abomasal mucosa. | The development of progastricsin-immunoreactive cells in the abomasal mucosa of cattle fetuses was studied by immunohistochemistry. Progastricsin-immunoreactive cells were detected first in the fundic and pyloric regions of 52 cm in crown-rump length (CRL) fetuses (about 180 days of gestation). The frequency of occurre... | ['Abomasum', 'Animals', 'Cattle', 'Chymosin', 'Enzyme Precursors', 'Female', 'Fetus', 'Humans', 'Immunohistochemistry', 'Mucous Membrane', 'Pepsinogens', 'Pregnancy'] | 7,612,956 | [['A13.869.106'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D08.811.277.656.074.500.200', 'D08.811.277.656.300.048.200'], ['D08.622', 'D12.776.811.243'], ['A16.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Precision Measurements and Parametric Models of Vertebral Endplates. | Detailed and comprehensive geometric data of vertebrae endplates is important and necessary to improve the fidelity of finite element models of the spine, design and ameliorate spinal implants, and understand degenerative changes and biomechanics. In this protocol, a high-speed and highly accurate scanner is employed t... | ['Biomechanical Phenomena', 'Finite Element Analysis', 'Humans', 'Models, Biological', 'Spine'] | 31,609,326 | [['G01.154.090', 'G01.374.089'], ['E05.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['A02.835.232.834']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Induction of cytochrome P450 3A4 by docetaxel in peripheral mononuclear cells and its expression in lung cancer. | Several recent studies have demonstrated that the cytochrome p450 (CYP) family plays an important role in the metabolism of taxanes. However, the role of CYP gene expression in tumors and peripheral mononuclear cells (PMN) is unknown. We therefore investigated the levels of CYP3A4 and CYP2C gene expression using revers... | ['Aged', 'Aged, 80 and over', 'Antineoplastic Agents, Phytogenic', 'Cytochrome P-450 CYP3A', 'Cytochrome P-450 Enzyme System', 'Docetaxel', 'Female', 'Humans', 'Leukocytes, Mononuclear', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Mixed Function Oxygenases', 'Paclitaxel', 'Taxoids'] | 11,488,523 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248.179'], ['D08.244.453.860.500', 'D08.811.682.662.582.353', 'D08.811.682.690.708.170.495.500', 'D12.776.422.220.453.860.500'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['D02.455.426.392.368.242.888.389', 'D02.455.849.291.850.389'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
MRCOG Part Two: Facing the viva. | The viva examination has two parts: the clinical and the viva voce. This article presents practical advice on how best to approach what is rightly felt by many to be the most hazardous part of the MRCOG Part Two examination. | ['Clinical Competence', 'Gynecology', 'Licensure', 'Obstetrics', 'Societies, Medical', 'United Kingdom'] | 1,591,550 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['H02.403.763.750', 'H02.403.810.310'], ['N03.706.110.510', 'N05.700.200.450'], ['H02.403.810.450'], ['N03.540.828.589'], ['Z01.542.363']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
A comparison between flow cytometric ploidy investigation and chromosome analysis of 32 human colorectal tumors. | The correlation between flow cytometric ploidy investigation and classic chromosome analysis was studied in 32 human colorectal tumors. Flow cytometry was performed by nuclei isolation and DNA staining with ethidium bromide. Chromosome analysis was done after incubation with colcemid. In 12 cases, chromosome identifica... | ['Colonic Neoplasms', 'Cytogenetics', 'DNA', 'Flow Cytometry', 'Humans', 'Ploidies', 'Rectal Neoplasms'] | 3,731,957 | [['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['H01.158.273.343.180'], ['D13.444.308'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05... | ['Diseases [C]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Neurologic complications of pediatric systemic malignancies. | From 1991 to 1995, we reviewed the medical records of 200 pediatric patients with systemic malignancies to study the occurrence of neurologic complications and their treatment. A total of 25 patients with neurologic complications were found. Complications included intracranial metastasis (one patient), intraspinal meta... | ['Adolescent', 'Brain Diseases', 'Central Nervous System Neoplasms', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Neoplasms', 'Neuroblastoma', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'Retrospective Studies', 'Taiwan'] | 8,857,252 | [['M01.060.057'], ['C10.228.140'], ['C04.588.614.250', 'C10.551.240'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['C04.557.465.625.600.590.650.550', 'C04.557.470.670.590.650.550', 'C04.557.580.625.600.590.650.550'], ['C04.557.337.428.600', 'C15.604.515.560.600', 'C2... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mechanical stress is communicated between different cell types to elicit matrix remodeling. | Tissue remodeling often reflects alterations in local mechanical conditions and manifests as an integrated response among the different cell types that share, and thus cooperatively manage, an extracellular matrix. Here we examine how two different cell types, one that undergoes the stress and the other that primarily ... | ['Bronchi', 'Cell Communication', 'Cell Division', 'Cells, Cultured', 'Coculture Techniques', 'Collagen', 'DNA-Binding Proteins', 'Early Growth Response Protein 1', 'Epithelial Cells', 'Extracellular Matrix', 'Fibroblasts', 'Fibronectins', 'Humans', 'Immediate-Early Proteins', 'Lung', 'Matrix Metalloproteinase 9', 'Res... | 11,353,845 | [['A04.411.125'], ['G04.085'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['E05.481.500.374'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D12.776.260'], ['D12.776.260.158.500', 'D12.776.460.525.500', 'D12.776.930.213.500'], ['A11.436'], ['A11.284.295.310'], ['A11.329.228']... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Bayesian estimation approach for the mortality in a stage-structured demographic model. | Control interventions in sustainable pest management schemes are set according to the phenology and the population abundance of the pests. This information can be obtained using suitable mathematical models that describe the population dynamics based on individual life history responses to environmental conditions and ... | ['Animals', 'Bayes Theorem', 'Computer Simulation', 'Insect Control', 'Likelihood Functions', 'Models, Biological', 'Mortality', 'Moths', 'Population Dynamics'] | 28,130,570 | [['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['L01.224.160'], ['N06.850.780.200.650.425'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.360.750.625.450', 'N06.850.520.830.500.475', 'N06.850.520.830.600.400'], ['E05.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
The quantitative evaluation of the Clinical and Translational Science Awards (CTSA) program based on science mapping and scientometric analysis. | The Clinical and Translational Science Awards (CTSA) program is one of the most important initiatives in translational medical funding. The quantitative evaluation of the efficiency and performance of the CTSA program has a significant referential meaning for the decision making of global translational medical funding.... | ['Awards and Prizes', 'Bibliometrics', 'Cluster Analysis', 'Humans', 'Periodicals as Topic', 'Program Evaluation', 'Research Support as Topic', 'Time Factors', 'Translational Medical Research'] | 24,330,689 | [['K01.150'], ['L01.178.682.099.325', 'L01.453.183.291'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.178.682.829.678'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['N03.219.483.645'], ['G01.910.857'], ['H01.770.644.145.675']] | ['Humanities [K]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Liver support in fulminant liver failure after hemorrhagic shock. | Acute liver failure (ALF) is a rare clinical syndrome associated with a mortality of up to 80% and its management remains an interdisciplinary challenge. Despite recent improvements in intensive care management, the mortality of patients with ALF remains high and is related to complications such as cerebral edema, seps... | ['APACHE', 'Adolescent', 'Critical Care', 'Follow-Up Studies', 'Hemodynamics', 'Humans', 'Insulinoma', 'Liver Failure', 'Liver Function Tests', 'Liver, Artificial', 'Male', 'Multiple Organ Failure', 'Pancreatic Neoplasms', 'Postoperative Complications', 'Respiration', 'Shock, Hemorrhagic', 'Time Factors'] | 14,531,174 | [['E05.318.308.980.438.475.365', 'E05.318.308.980.438.475.456.500.250', 'N05.715.360.300.800.438.375.364.500.250', 'N06.850.520.308.980.438.475.364.500.250'], ['M01.060.057'], ['E02.760.190', 'N02.421.585.190'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G09.330.380'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Magnetic resonance imaging and angiography for the prerupture diagnosis of rudimentary uterine horn pregnancy. | Magnetic resonance (MR) imaging and MR angiography were used for the differential diagnosis and preoperative planning of a 17 weeks of age rudimentary horn pregnancy. A 26-year-old primigravida was referred to our hospital with a preliminary diagnosis of abdominal pregnancy. After an inconclusive ultrasound evaluation ... | ['Adult', 'Female', 'Humans', 'Magnetic Resonance Angiography', 'Magnetic Resonance Imaging', 'Pregnancy', 'Pregnancy, Abdominal', 'Radiography', 'Uterus'] | 15,690,621 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500.500', 'E01.370.370.050.500'], ['E01.370.350.825.500'], ['G08.686.784.769'], ['C13.703.733.536'], ['E01.370.350.700'], ['A05.360.319.679']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Stabilisation of SWNTs by alkyl-sulfate chitosan derivatives of different molecular weight: towards the preparation of hybrids with anticoagulant properties. | We have previously demonstrated that chitosan derivative N-octyl-O-sulfate chitosan (NOSC), which presents important pharmacological properties, can suspend single walled carbon nanotubes (SWNTs) up to 20 times more effectively than other chitosan derivatives in an aqueous environment. In an attempt to further investig... | ['Anticoagulants', 'Blood Coagulation', 'Chitosan', 'Excipients', 'Humans', 'Materials Testing', 'Molecular Weight', 'Nanotubes, Carbon', 'Particle Size'] | 21,258,715 | [['D27.505.954.502.119'], ['G09.188.390.150'], ['D05.750.078.139.500', 'D09.698.211.500'], ['D26.650.700.419', 'D27.720.744.770.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.570'], ['G02.494'], ['D01.268.150.250.500', 'J01.637.512.850.500'], ['G02.712']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Bidirectional child-family influences on outcomes of traumatic brain injury in children. | Child behavior problems, injury-related family burden, and parent psychological distress were assessed longitudinally over the first year post injury in 40 children with severe traumatic brain injury (TBI), 52 with moderate TBI, and 55 with orthopedic injuries not involving brain insult. Parents rated children's preinj... | ['Brain Injuries', 'Child', 'Child Behavior Disorders', 'Cost of Illness', 'Family', 'Female', 'Follow-Up Studies', 'Glasgow Coma Scale', 'Humans', 'Male', 'Outcome Assessment, Health Care', 'Parents', 'Prognosis', 'Prospective Studies', 'Psychiatric Status Rating Scales', 'Stress, Psychological'] | 11,575,597 | [['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['M01.060.406'], ['F03.625.141'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['F01.829.263', 'I01.880.853.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.31... | ['Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Dosimetric comparison of three-dimensional conformal radiotherapy in salvage radiotherapy for PSA relapse after radical prostatectomy. | The purpose of this study is to compare three-dimensional conformal radiotherapy (3D-CRT) plans in a setting of salvage radiotherapy after radical prostatectomy (RP) and to simulate whether dose escalation is possible with the most adequate 3D-CRT technique. This study included consecutive 10 patients underwent salvage... | ['Dose-Response Relationship, Radiation', 'Humans', 'Male', 'Prostate-Specific Antigen', 'Prostatectomy', 'Prostatic Neoplasms', 'Radiotherapy, Conformal', 'Recurrence'] | 20,921,825 | [['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.760.442.750', 'D08.811.277.656.959.350.442.750', 'D12.776.866.249.500', 'D23.050.285.625', 'D23.101.140.625'], ['E04.950.774.860.625'], ['C04.58... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Insulin treatment of corticosteroid-associated hyperglycemia and its effect on outcome after forebrain ischemia in rats. | BACKGROUND: Recent studies have reported that dexamethasone worsens neuronal injury after brain ischemia. This effect is assumed to be secondary to drug-induced hyperglycemia. The current study used a rat model to test the hypotheses that insulin treatment of dexamethasone-induced hyperglycemia would result in a postis... | ['Animals', 'Brain', 'Brain Ischemia', 'Dexamethasone', 'Hyperglycemia', 'Insulin', 'Male', 'Prosencephalon', 'Rats', 'Rats, Sprague-Dawley'] | 8,659,793 | [['B01.050'], ['A08.186.211'], ['C10.228.140.300.150', 'C14.907.253.092'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['C18.452.394.952'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['A08.186.211.200'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The structure of recombinant plasminogen kringle 1 and the fibrin binding site. | The structure of recombinant (Hoover et al. Biochemistry, 1993; 32:10936-10944) plasminogen (PG) kringle 1 (K1) has been determined and refined at 2.48 A resolution to a crystallographic R value of 0.159. In addition, 71 water molecules and two chloride ions have been located. The folding of PGK1 is very similar to tha... | ['Amino Acid Sequence', 'Binding Sites', 'Crystallization', 'Fibrin', 'Kringles', 'Lysine', 'Molecular Sequence Data', 'Plasminogen', 'Protein Conformation', 'Recombinant Proteins'] | 8,054,447 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['E05.196.300', 'G02.171'], ['D12.776.124.270'], ['G02.111.570.820.709.275.750.375'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['L01.453.245.667'], ['D08.622.610', 'D12.776.124.790.223.580', 'D12.776.377.715.182.580', 'D12.776.811.243.6... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Comparison of effects of neuropeptide Y and norepinephrine on insulin secretion and vascular resistance in perfused rat pancreas. | Neuropeptide Y (NPY) and norepinephrine (NE) behave like cotransmitters in intrapancreatic adrenergic nerves. Therefore, in the isolated rat pancreas, we 1) studied and compared the effect of increasing concentrations of NE and NPY given alone on insulin secretion induced by 8.3 mM glucose and on pancreatic vascular fl... | ['Animals', 'Dose-Response Relationship, Drug', 'In Vitro Techniques', 'Insulin', 'Insulin Secretion', 'Islets of Langerhans', 'Kinetics', 'Male', 'Neuropeptide Y', 'Norepinephrine', 'Pancreas', 'Perfusion', 'Rats', 'Rats, Inbred Strains', 'Time Factors', 'Vascular Resistance'] | 2,040,381 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.481'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.442', 'G07.475'], ['A03.734.414', 'A06.300.414'], ['G01.374.661', 'G02.111.490'], ['D12.644.400.500', 'D12.776.631.650.500'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.2... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Solid tumors in patients treated for Hodgkin's disease: a report from the German Hodgkin Lymphoma Study Group. | BACKGROUND: Long-term survivors of successfully treated Hodgkin's disease (HD) are at risk for late complications. Among these, secondary solid tumors are most serious because they are often fatal. The aim of this retrospective analysis was to assess the incidence, relative risk and risk factors of secondary solid tumo... | ['Adolescent', 'Adult', 'Breast Neoplasms', 'Female', 'Follow-Up Studies', 'Gastrointestinal Neoplasms', 'Germany', 'Hodgkin Disease', 'Humans', 'Incidence', 'Lung Neoplasms', 'Male', 'Melanoma', 'Middle Aged', 'Neoplasm Staging', 'Prognosis', 'Retrospective Studies', 'Risk Factors', 'Survival Analysis', 'Time Factors'... | 15,205,202 | [['M01.060.057'], ['M01.060.116'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['Z01.542.315'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B01.050.150.900.649.3... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mechanisms of impulsive choice: I. Individual differences in interval timing and reward processing. | Impulsive choice behavior incorporates the psychological mechanisms involved in the processing of the anticipated magnitude and delay until reward. The goal of the present experiment was to determine whether individual differences in such processes related to individual differences in impulsive choice behavior. Two gro... | ['Animals', 'Choice Behavior', 'Conditioning, Operant', 'Delay Discounting', 'Impulsive Behavior', 'Individuality', 'Male', 'Rats', 'Rats, Sprague-Dawley', 'Reward', 'Time Factors'] | 24,965,705 | [['B01.050'], ['F02.463.785.373.346'], ['F02.463.425.179.509'], ['F02.463.785.373.346.700'], ['F01.145.527'], ['F01.752.488'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['F02.463.425.770.836'], ['G01.910.857']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Infected left atrial myxoma caused by Gemella morbillorum. | Gemella morbillorum was isolated from the blood of a 38-year-old woman with a 4-week history of fever. An echocardiogram showed a left atrial tumor. The patient was successfully treated by antibiotic therapy and early surgical excision of the tumor. Histological examination of the excised tumor revealed a typical myxom... | ['Adult', 'Aminoglycosides', 'Anti-Bacterial Agents', 'Female', 'Heart Atria', 'Heart Neoplasms', 'Humans', 'Myxoma', 'Penicillins', 'Streptococcaceae', 'Ultrasonography'] | 9,060,070 | [['M01.060.116'], ['D09.408.051'], ['D27.505.954.122.085'], ['A07.541.358'], ['C04.588.894.309', 'C14.280.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.565.550'], ['D02.065.589.099.750', 'D02.886.108.750', 'D03.633.100.300.750'], ['B03.353.750.737', 'B03.510.400.800', 'B03.510.550.737'], ['E01.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Increased plasma level of endothelin-1 in the Okamoto spontaneously hypertensive rat. | The objectives of this study were to determine plasma levels of endothelin (ET) in a genetic model of hypertension and in control rats during control conditions and in response to short-term volume expansion with saline. Okamoto spontaneously hypertensive rats (SHR) and control Wistar-Kyoto (WKY) rats were used in this... | ['Animals', 'Endothelins', 'Male', 'Plasma Substitutes', 'Rats', 'Rats, Inbred SHR', 'Rats, Inbred WKY', 'Sodium Chloride'] | 8,417,254 | [['B01.050'], ['D12.644.276.400', 'D12.776.467.400', 'D23.529.400'], ['D27.505.954.502.140.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.300', 'B01.050.150.900.649.313.992.635.505.700.400.300'], ['B01.050.050.199.520.760.390', 'B01.050.150.900.649.313.992.635.505.700.400.390'], ['D01.210... | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of copper-responsive genes in an early life stage of the fathead minnow Pimephales promelas. | While physiological changes associated with copper toxicity have been studied in adult fathead minnow, Pimephales promelas, little is known about the effect of copper on newly hatched larvae. As a result we initiated an investigation on the mechanism of copper toxicity in 24 h post-hatch larvae using gene expression ch... | ['Animals', 'Copper', 'Cyprinidae', 'Dose-Response Relationship, Drug', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Genes', 'Larva', 'Reverse Transcriptase Polymerase Chain Reaction', 'Toxicity Tests'] | 19,020,976 | [['B01.050'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['B01.050.150.900.493.200.244'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.393.332'], ['G05.308'], ['G05.360.340.024.340'], ['B05.500.500', 'G07.345.500.550.500.500'], ['E05.393.620.500.725'], ['E05.940']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthesis and Properties of Bis-Porphyrin Molecular Tweezers: Effects of Spacer Flexibility on Binding and Supramolecular Chirogenesis. | Ditopic binding of various dinitrogen compounds to three bisporphyrin molecular tweezers with spacers of varying conformational rigidity, incorporating the planar enediyne (1), the helical stiff stilbene (2), or the semi-rigid glycoluril motif fused to the porphyrins (3), are compared. Binding constants Ka = 10⁴-10⁶ M(... | ['Circular Dichroism', 'Macromolecular Substances', 'Models, Molecular', 'Molecular Structure', 'Porphyrins'] | 26,703,562 | [['E05.196.867.151'], ['D05'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['D03.383.129.578.840.500', 'D03.633.400.909.500', 'D04.345.783.500', 'D23.767.727']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cinacalcet may reduce arterial stiffness in patients with chronic renal disease and secondary hyperparathyroidism - results of a small-scale, prospective, observational study. | AIMS: This study evaluated the impact of cinacalcet on arterial stiffness, determined by pulse wave velocity (PWV), in patients with chronic renal disease and secondary hyperparathyroidism (SHPT).PATIENTS AND METHODS: This prospective, observational study included, SHPT patients with chronic renal disease on dialysis u... | ['Adult', 'Aged', 'Alkaline Phosphatase', 'Aorta', 'Aortic Diseases', 'Biomarkers', 'Blood Pressure', 'Calcimimetic Agents', 'Calcium', 'Cinacalcet', 'Elasticity', 'Female', 'Humans', 'Hyperparathyroidism, Secondary', 'Hypertrophy, Left Ventricular', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Naphthalenes', 'Pa... | 21,329,627 | [['M01.060.116'], ['M01.060.116.100'], ['D08.811.277.352.650.035'], ['A07.015.114.056'], ['C14.907.109'], ['D23.101'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D06.347.230', 'D27.505.696.399.450.230'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.455.426.559.847.638.183', 'D04.615.638.183'], ['G01.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Doxorubicin-induced cardiotoxicity monitored by ECG in freely moving mice. A new model to test potential protectors. | In laboratory animals, histology is most commonly used to study doxorubicin-induced cardiotoxicity. However, for monitoring during treatment, large numbers of animals are needed. Recently we developed a new method to measure ECG values in freely moving mice by telemetry. With this model we investigated the effect of ch... | ['Analysis of Variance', 'Animals', 'Antineoplastic Agents, Alkylating', 'Behavior, Animal', 'Body Weight', 'Cardiomyopathies', 'Cardiovascular Agents', 'Doxorubicin', 'Drug Interactions', 'Electrocardiography', 'Heart', 'Heart Atria', 'Heart Rate', 'Injections, Intraperitoneal', 'Injections, Intravenous', 'Male', 'Mic... | 8,603,459 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D27.505.519.124.035', 'D27.505.954.248.150', 'D27.888.569.035.035'], ['F01.145.113'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C14.280.238'], ['D27.505.954.411... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
BIPP madness; an iatrogenic cause of acute confusion. | An 81-year-old man, admitted under the Ear, Nose and Throat Team with persistent epistaxis, developed an acute confusional state. He was previously physically independent and mentally competent. Immediate investigations did not reveal a cause for his deterioration. He eventually made a full recovery and returned home. ... | ['Acute Disease', 'Aged', 'Aged, 80 and over', 'Bismuth', 'Confusion', 'Drug Combinations', 'Epistaxis', 'Humans', 'Hydrocarbons, Iodinated', 'Male'] | 15,082,418 | [['C23.550.291.125'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D01.268.271.245', 'D01.268.556.100', 'D01.496.749.305.245', 'D01.552.544.100'], ['C10.597.606.337', 'C23.888.592.604.339', 'F01.700.250'], ['D26.310'], ['C08.460.261', 'C09.603.261', 'C23.550.414.712', 'C23.888.852.040'], ['B01.050.150.900.649.313.98... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Impact of Atmospheric Microparticles on the Development of Oxidative Stress in Healthy City/Industrial Seaport Residents. | Atmospheric microsized particles producing reactive oxygen species can pose a serious health risk for city residents. We studied the responses of organisms to microparticles in 255 healthy volunteers living in areas with different levels of microparticle air pollution. We analyzed the distribution of microparticles in ... | ['Adult', 'Antioxidants', 'DNA', 'DNA Damage', 'Female', 'Glutathione', 'Healthy Volunteers', 'Humans', 'Leukocytes', 'Lipid Peroxidation', 'Male', 'Oxidative Stress', 'Particle Size', 'Particulate Matter', 'Snow', 'Thioredoxins'] | 26,064,419 | [['M01.060.116'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D13.444.308'], ['G05.200'], ['D12.644.456.448'], ['M01.774.500', 'M01.955.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['G02.111.515', 'G03.295.531.587'], ['G03.673', 'G07.775... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
3-Aminobenzamide, a poly (ADP-ribose) synthetase inhibitor, attenuates the acute inflammatory responses and brain injury in experimental Escherichia coli meningitis in the newborn piglet. | The aim of the present study was to evaluate the anti-inflammatory and neuroprotective effects of a poly (ADP-ribose) synthetase inhibitor 3-aminobenzamide during the early phase of experimental bacterial meningitis in the newborn piglet. Meningitis was induced by intracisternal injection of 10(8) colony forming units ... | ['Acute Disease', 'Animals', 'Animals, Newborn', 'Benzamides', 'Brain', 'Cerebral Cortex', 'Colony Count, Microbial', 'Encephalitis', 'Enzyme Inhibitors', 'Escherichia coli', 'Glucose', 'Lactic Acid', 'Leukocyte Count', 'Meningitis, Escherichia coli', 'Poly Adenosine Diphosphate Ribose', 'Poly(ADP-ribose) Polymerase In... | 11,428,523 | [['C23.550.291.125'], ['B01.050'], ['B01.050.050.282'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['A08.186.211'], ['A08.186.211.200.885.287.500'], ['E01.370.225.875.220', 'E05.200.875.220'], ['C10.228.140.430'], ['D27.505.519.389'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], [... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Silver nanoparticles enhance wound healing in zebrafish (Danio rerio). | Silver nanoparticles (AgNPs) were successfully synthesized by a chemical reduction method, physico-chemically characterized and their effect on wound-healing activity in zebrafish was investigated. The prepared AgNPs were circular-shaped, water soluble with average diameter and zeta potential of 72.66 nm and -0.45 mv, ... | ['Animals', 'Gene Expression', 'Metal Nanoparticles', 'Silver', 'Wound Healing', 'Zebrafish'] | 28,757,200 | [['B01.050'], ['G05.297'], ['J01.637.512.600.500'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.544.812'], ['G16.762.891'], ['B01.050.150.900.493.200.244.828']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Total quality management in clinical virology laboratories. | The diagnostic laboratories in India are progressively promoting higher standards and are moving towards accreditation and international acceptance. Hence, the concept of "Quality" will need to be understood and implemented. Total quality management (TQM) in a laboratory is an integrated program involving all laborator... | ['Accreditation', 'Clinical Competence', 'Clinical Laboratory Techniques', 'Humans', 'India', 'Laboratories', 'Quality Control', 'Total Quality Management', 'Virology', 'Virus Diseases', 'Viruses'] | 17,185,843 | [['N03.706.110.070', 'N05.700.200.100'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E01.370.225', 'E05.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['J03.520', 'N02.278.487'], ['J01.897.608'], ['N04.452.955', 'N04.761.700.675', 'N05.700.792'], ['H01.158.273.540.859'], ['C01.925... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
The ribose 5-phosphate isomerase-encoding gene is located immediately downstream from that encoding murine immunoglobulin kappa. | The immunoglobulin kappa locus (Ig kappa) is active only in the B-lymphocyte cell lineage. By exon-trapping we found a gene situated downstream from the murine Ig kappa locus. This gene encodes a protein with 53% sequence identity to the ribose 5-phosphate isomerase A (RPI-A) of Escherichia coli and is therefore likely... | ['Aldose-Ketose Isomerases', 'Amino Acid Sequence', 'Animals', 'Base Sequence', 'Biological Evolution', 'Carbohydrate Epimerases', 'Chromosome Mapping', 'Conserved Sequence', 'DNA, Complementary', 'Exons', 'Gene Expression', 'Genes, Immunoglobulin', 'Genomic Library', 'Immunoglobulin kappa-Chains', 'Mice', 'Mice, Inbre... | 7,758,956 | [['D08.811.399.475.200'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045', 'G16.075'], ['D08.811.399.894.500'], ['E05.393.183'], ['G02.111.570.580'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G05.360.34... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
L-mandelate dehydrogenase from Rhodotorula graminis: comparisons with the L-lactate dehydrogenase (flavocytochrome b2) from Saccharomyces cerevisiae. | L-Lactate dehydrogenase (L-LDH) from Saccharomyces cerevisiae and L-mandelate dehydrogenase (L-MDH) from Rhodotorula graminis are both flavocytochromes b2. The kinetic properties of these enzymes have been compared using steady-state kinetic methods. The most striking difference between the two enzymes is found by comp... | ['Alcohol Oxidoreductases', 'Amino Acid Sequence', 'Binding Sites', 'Binding, Competitive', 'Catalysis', 'Kinetics', 'L-Lactate Dehydrogenase', 'Lactates', 'Lactic Acid', 'Mandelic Acids', 'Models, Molecular', 'Molecular Sequence Data', 'Molecular Structure', 'Oxidation-Reduction', 'Rhodotorula', 'Saccharomyces cerevis... | 8,439,280 | [['D08.811.682.047'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['G02.130'], ['G01.374.661', 'G02.111.490'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['D02.241.511.459'], ['D02.241.511.459.450'], ['D02.241.223.475', 'D02.241.51... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Transient rheological behavior of blood in low-shear tube flow: velocity profiles and effective viscosity. | Velocity profiles of human blood flowing through vertical and horizontal glass tubes (25-100 microns ID) were measured as a function of time following a sudden reduction of wall shear stress (tau w) from a high value to values ranging from 2 to 100 mPa. Cell velocities at various radial positions were determined off-li... | ['Blood Flow Velocity', 'Blood Viscosity', 'Capillary Action', 'Humans', 'Models, Cardiovascular', 'Perfusion', 'Plethysmography', 'Rheology', 'Stress, Mechanical'] | 7,840,268 | [['E01.370.370.130', 'G09.330.380.630.080'], ['G09.188.370.124', 'G09.330.380.630.110'], ['G02.860.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.161'], ['E05.680'], ['E01.370.370.610'], ['E05.830', 'H01.671.808'], ['G01.374.835']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Stereotactic Radiosurgery in the Management of Limited (1-4) Brain Metasteses: Systematic Review and International Stereotactic Radiosurgery Society Practice Guideline. | BACKGROUND: Guidelines regarding stereotactic radiosurgery (SRS) for brain metastases are missing recently published evidence.OBJECTIVE: To conduct a systematic review and provide an objective summary of publications regarding SRS in managing patients with 1 to 4 brain metastases.METHODS: Using Preferred Reporting Item... | ['Brain Neoplasms', 'Cranial Irradiation', 'Humans', 'Radiosurgery', 'Salvage Therapy'] | 29,126,142 | [['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E02.815.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.815.530', 'E04.525.800.650', 'E05.873.500'], ['E02.895']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Performance Evaluation of a Newly Developed Chemiluminescent Assay Kit for Detection of Neuron-Specific Eno. | BACKGROUND: To evaluate the performance of a chemiluminescence detection reagent for Neuron-specific enolase (NSE).METHODS: Based on the "Guiding principles on performance analysis of diagnostic, reagents in vitro" and the Clinical and Laboratory Standards Institute (CLSI) Guidelines, performance of the CLIA NSE kit wa... | ['Guidelines as Topic', 'Humans', 'Limit of Detection', 'Luminescent Measurements', 'Phosphopyruvate Hydratase', 'Reagent Kits, Diagnostic', 'Reproducibility of Results'] | 30,146,825 | [['N04.761.700.350', 'N05.700.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['E05.196.712.516'], ['D08.811.520.241.300.500'], ['D27.505.259.875', 'D27.720.470.410.680', 'E07.720'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.32... | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Symptom expression in hyperactive children: an analysis of observations. | Hyperactivity is typically diagnosed when children display overactivity, inappropriate inattention, and impulsivity during the school day when involved in tasks that require sustained and voluntary attention. However, distinguishing children with hyperactivity from children with other learning and behavior disorders is... | ['Adolescent', 'Attention', 'Attention Deficit Disorder with Hyperactivity', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Learning Disabilities', 'Male', 'Motor Activity', 'Touch'] | 2,703,786 | [['M01.060.057'], ['F02.830.104.214'], ['F03.625.094.150'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.150.550', 'C23.888.592.604.150.550', 'F03.625.562'], ['F01.145.632', 'G11.427.410.698'], ['F02.830.816.850', 'G11.561.790.850']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Benchmarking as everyday functional assessment in stroke recovery. | OBJECTIVES: Functional assessment in stroke recovery extends beyond formal testing and evaluation. Stroke survivors themselves continuously engage in the process of reckoning their functional capacities as they go about their everyday lives. This process is called benchmarking. The aim of this article is to discuss and... | ['Activities of Daily Living', 'Adaptation, Psychological', 'Aged', 'Benchmarking', 'Cerebral Infarction', 'Comorbidity', 'Disability Evaluation', 'Humans', 'Interview, Psychological', 'Self-Assessment', 'Sick Role', 'Social Adjustment'] | 12,878,653 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['F01.058'], ['M01.060.116.100'], ['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Female reproductive decline is determined by remaining ovarian reserve and age. | The early decline and loss of female fertility in humans and other species represents an evolutionary paradox. Despite being born with a vast stock of oocytes, females encounter an exhaustion of ovarian reserve and sterility half way through their natural lives. Female reproductive ageing has been proposed to proceed a... | ['Adult', 'Age Factors', 'Female', 'Follicle Stimulating Hormone', 'Humans', 'Middle Aged', 'Ovarian Follicle', 'Ovarian Reserve', 'Ovariectomy', 'Ovary', 'Reproduction', 'Young Adult'] | 25,310,678 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A05.360.319.114.630.535', 'A06.300.312.497.535'], ['G08.686.210.249', 'G08.686.628'], ['E04.270.282... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hip arthroplasty for failed internal fixation of intertrochanteric and subtrochanteric fractures in the elderly patient. | Failure of internal fixation in hip fractures can lead to difficult problems, especially in elderly patients. At the intertrochanteric or subtrochanteric level a prosthesis with diaphyseal support is one of the solutions to this problem. In 12 patients an endoprosthesis was performed for failed internal fixation. The m... | ['Aged', 'Aged, 80 and over', 'Bone Nails', 'Bone Plates', 'Female', 'Fracture Healing', 'Hip Fractures', 'Hip Prosthesis', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Reoperation', 'Treatment Failure'] | 8,053,339 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E07.695.370.249', 'E07.858.442.660.460.249', 'E07.858.690.725.460.249'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['G16.762.891.500'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['E07.695.400.400'], ['B01.050.150.900.649.313.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pleomorphic (spindle and squamous cell) carcinoma arising in a peripheral mixed squamous and glandular papilloma in a 70-year-old man. | Solitary papillomas of the bronchial tree are rare, particularly in the distal airways. When encountered, solitary papillomas are not frequently found to undergo malignant transformation. When this does happen, it is usually a squamous cell carcinoma arising in a human papillomavirus-associated squamous papilloma (usua... | ['Aged', 'Bronchial Neoplasms', 'Carcinoma, Squamous Cell', 'Diagnosis, Differential', 'Humans', 'Male', 'Neoplasms, Complex and Mixed', 'Papilloma', 'Papillomaviridae'] | 21,970,492 | [['M01.060.116.100'], ['C04.588.894.797.520.109', 'C08.127.265', 'C08.785.520.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.435'], ['C04.557.470.700.600'], ['B04.280.210.655', 'B04.613.204.655']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Midori de Habich: the economist who ran Peru's health ministry. | Midori de Habich speaks to Gary Humphreys about Peru's journey towards universal health coverage and the advantages of being an economist in a world of doctors. | ['Administrative Personnel', 'Delivery of Health Care', 'Economics, Medical', 'Government Agencies', 'Peru', 'Policy Making'] | 32,015,577 | [['M01.526.070'], ['N04.590.374', 'N05.300'], ['N03.219.300'], ['I01.409.418', 'N03.540.400'], ['Z01.107.757.702'], ['N03.706.742']] | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Morniga-G, a T/Tn-Specific Lectin, Induces Leukemic Cell Death via Caspase and DR5 Receptor-Dependent Pathways. | Morniga-G, the Gal-specific black mulberry (Morus nigra) lectin, displays high affinity for T (CD176) and Tn (CD175) antigens, frequently expressed at the cancer cell surface. The effects of Morniga-G were investigated on a Tn-positive leukemic Jurkat cell line. The lectin, used in a concentration range between 5⁻20 ìg... | ['Antigens, Tumor-Associated, Carbohydrate', 'Caspases', 'Cell Death', 'Cell Membrane', 'Ceramides', 'Glycosylation', 'Humans', 'Jurkat Cells', 'Lectins', 'Leukemia', 'Lymphocytes', 'Mitochondria', 'Morus', 'Protein Aggregates', 'Receptors, TNF-Related Apoptosis-Inducing Ligand'] | 30,626,136 | [['D23.050.285.050', 'D23.050.550.325', 'D23.101.140.075'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['G04.146'], ['A11.284.149'], ['D02.065.313', 'D09.400.410.420.525.200', 'D10.390.470.675.200', 'D10.570.877.360.612.200'], ['G02.111.158.812', 'G02.6... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Overexpression of alfalfa Orange gene in tobacco enhances carotenoid accumulation and tolerance to multiple abiotic stresses. | The multifunctional Orange (Or) protein plays crucial roles in carotenoid homeostasis, photosynthesis stabilization, and antioxidant activity in plants under various abiotic stress conditions. The Or gene has been cloned in several crops but not in alfalfa (Medicago sativa L.). Alfalfa is widely cultivated across the w... | ['Carotenoids', 'Chloroplasts', 'Dehydration', 'Gene Expression Profiling', 'Genes, Plant', 'Heat-Shock Proteins', 'Heat-Shock Response', 'Medicago sativa', 'Oxidative Stress', 'Plant Proteins', 'Plants, Genetically Modified', 'Reverse Transcriptase Polymerase Chain Reaction', 'Salt Tolerance', 'Tobacco'] | 30,121,513 | [['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['A11.284.430.214.190.875.700.140'], ['C18.452.950.179', 'C23.550.274'], ['E05.393.332'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['D12.776.580.216'], ['G07.775.500'], ['B01.650.940.800.575.912.250.401.590.500... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impaired long-term expansion and self-renewal potential of pediatric acute myeloid leukemia-initiating cells by PTK787/ZK 222584. | Although most children with acute myeloid leukemia (AML) achieve complete remission, the relapse rate is 30% to 40%. Because it is thought that leukemia-initiating cells (LIC) are responsible for AML relapses, targeting these cells might improve outcome. Treatment of pediatric AML blasts with the receptor tyrosine kina... | ['Antibodies, Monoclonal, Humanized', 'Bevacizumab', 'Cell Growth Processes', 'Cell Line, Tumor', 'Child', 'Child, Preschool', 'Female', 'HL-60 Cells', 'Humans', 'Leukemia, Myeloid, Acute', 'Male', 'Phosphorylation', 'Phthalazines', 'Protein Kinase Inhibitors', 'Pyridines', 'Recurrence', 'Survival Analysis', 'Transduct... | 23,393,162 | [['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D12.776.124.486.485.114.224.060.375', 'D12.776.124.790.651.114.224.060.438', 'D12.776.377.715.548.114.224.200.438'], ['G04.161', 'G07.345.249.410'], ['A11.251.210.190', 'A11.251.860.180'], ['M01.060.406'], ['M0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fcgamma-receptor IIA genotype and invasive pneumococcal infection. | Streptococcus pneumoniae is a major cause of pneumonia, bacteraemia, meningitis, and acute otitis media, especially in young children, immunocompromised patients, and elderly. Fcgamma-IIA receptor plays a crucial role in the phagocytosis of IgG2-opsonized bacteria since it is the sole receptor able to interact with IgG... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Antigens, CD', 'Child', 'Child, Preschool', 'Demography', 'European Continental Ancestry Group', 'Female', 'Gene Frequency', 'Genotype', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Pneumococcal Infections', 'Polymorphism, Genetic', 'Prospective Studie... | 16,150,646 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.050.301.264.035', 'D23.101.100.110'], ['M01.060.406'], ['M01.060.406.448'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['M01.686.508.400'], ['G05.330'], ['G05.380'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Prolonged Capecitabine Chemotherapy Following Capecitabine and Oxaliplatin (CAPOX) Regimen Chemotherapy Failed to Improve Survival of Stage III Colorectal Cancer After Radical Resection. | BACKGROUND Colorectal cancer (CRC) is considered to be a worldwide health problem because of its increasing incidence and prevalence. Surgery offers an opportunity for cure, but the postoperative recurrence rate is still high despite the advancement of chemotherapy. This study aimed to assess the efficacy and safety of... | ['Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Capecitabine', 'Chemotherapy, Adjuvant', 'Colorectal Neoplasms', 'Disease-Free Survival', 'Drug Administration Schedule', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Oxaliplatin', 'Retrospective Studies'] | 31,254,462 | [['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D03.383.742.680.245.500.425', 'D03.383.742.698.875.404.425', 'D13.570.230.329.313', 'D13.570.685.245.500.425'], ['E02.186.170', 'E02.319.170'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.35... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Regulation of hyaluronan synthases in mouse uterine cervix. | We examined the expression pattern of hyaluronan synthase (HAS) mRNAs in the uterine cervix of pregnant mice. The expression levels of HAS-1 and -2 mRNAs peaked at delivery, whereas that of HAS-3 mRNA peaked on the 15th day of pregnancy. The regulation of HAS mRNA expression was examined in pregnant mouse uterine cervi... | ['Animals', 'Base Sequence', 'Cervix Uteri', 'Female', 'Fibroblasts', 'Gene Expression Regulation, Enzymologic', 'Glucuronosyltransferase', 'Hyaluronan Synthases', 'Hyaluronic Acid', 'Inflammation', 'Interleukin-1', 'Keratinocytes', 'Mice', 'Molecular Weight', 'Pregnancy', 'Progesterone', 'RNA, Messenger', 'Serum', 'Tr... | 15,649,434 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A05.360.319.679.256'], ['A11.329.228'], ['G05.308.320'], ['D08.811.913.400.450.480'], ['D08.811.913.400.450.480.500'], ['D09.698.373.475'], ['C23.550.470'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury. | Cerebrocortical injuries such as stroke are a major source of disability. Maladaptive consequences can result from post-injury local reorganization of cortical circuits. For example, epilepsy is a common sequela of cortical stroke, but the mechanisms responsible for seizures following cortical injuries remain unknown. ... | ['Action Potentials', 'Age Factors', 'Animals', 'Animals, Newborn', 'Biophysical Phenomena', 'Biophysics', 'Brain Injuries', 'Calcium-Calmodulin-Dependent Protein Kinase Type 2', 'Cerebral Cortex', 'Cyclic Nucleotide-Gated Cation Channels', 'Disease Models, Animal', 'Electric Capacitance', 'Electric Stimulation', 'Elec... | 23,143,518 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['B01.050.050.282'], ['G01.154'], ['H01.158.344', 'H01.671.100'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['D08.811.913.696.620.682.700.125.200', 'D12.644.360.100.200', 'D12.776.476.100.200'],... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparative Effects of Different Assistance Force During Robot-Assisted Gait Training on Locomotor Functions in Patients With Subacute Stroke: An Assessor-Blind, Randomized Controlled Trial. | OBJECTIVE: The aim of the study was to compare the effects of progressive reducing assistance force versus full assistance force controlled robot-assisted gait training combined with conventional physiotherapy on locomotor functions in patients with subacute stroke.DESIGN: Inpatients with subacute stroke (N = 29; 16 me... | ['Aged', 'Female', 'Gait', 'Gait Disorders, Neurologic', 'Humans', 'Locomotion', 'Male', 'Middle Aged', 'Physical Therapy Modalities', 'Recovery of Function', 'Robotics', 'Single-Blind Method', 'Stroke', 'Stroke Rehabilitation', 'Treatment Outcome', 'Walking'] | 30,142,092 | [['M01.060.116.100'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['C10.597.404', 'C23.888.592.413'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568.500', 'G11.427.410.568'], ['M01.060.116.630'], ['E02.779', 'E02.831.535'], ['G16.757'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630'], ['E0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Health Care [N]', 'Anthropology, Education, Sociology, ... | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
What Is the Most Useful Questionnaire for Measurement of Coping Strategies in Response to Nociception? | BACKGROUND: There are several measures of coping strategies in response to nociception. These measures all correlate highly both with each other and with symptom intensity and magnitude of disability in patients with upper limb illness. This study aims to determine if distinct measures of coping strategies in response ... | ['Adaptation, Psychological', 'Adult', 'Catastrophization', 'Cross-Sectional Studies', 'Disability Evaluation', 'Factor Analysis, Statistical', 'Female', 'Humans', 'Illness Behavior', 'Linear Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Musculoskeletal Pain', 'Nociception', 'Pain Measurement', 'Predictive ... | 26,105,152 | [['F01.058'], ['M01.060.116'], ['F01.100.575', 'F01.470.132.225'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.400'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.499'], ['E05.318.740.500.500', ... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Thyroid transcription factor-2 gene expression in benign and malignant thyroid lesions. | Thyroid transcription factor-2 (TTF-2) is a recently cloned thyroid-specific gene and is central to the development and differentiation of the thyroid follicular cell. Information regarding transcript levels in normal and diseased adult human thyroids is lacking. We have investigated TTF-2 gene expression in various th... | ['Adult', 'Biopsy, Needle', 'Cell Differentiation', 'DNA, Neoplasm', 'DNA-Binding Proteins', 'Forkhead Transcription Factors', 'Gene Expression Regulation, Neoplastic', 'Humans', 'In Situ Hybridization', 'Iodide Peroxidase', 'Phenotype', 'Repressor Proteins', 'Reverse Transcriptase Polymerase Chain Reaction', 'Thyroid ... | 11,762,722 | [['M01.060.116'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['G04.152'], ['D13.444.308.425'], ['D12.776.260'], ['D12.776.260.950.249', 'D12.776.930.977.249'], ['G05.308.370'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Growth Properties and Biomass Production in the Hybrid C4 Crop Sorghum bicolor. | Hybrid vigor (heterosis) has been used as a breeding technique for crop improvement to achieve enhanced biomass production, but the physiological mechanisms underlying heterosis remain poorly understood. In this study, to find a clue to the enhancement of biomass production by heterosis, we systemically evaluated the e... | ['Biomass', 'Carbon Dioxide', 'Chlorophyll', 'Hybrid Vigor', 'Nitrogen', 'Phosphoenolpyruvate Carboxylase', 'Photosynthesis', 'Plant Leaves', 'Plant Proteins', 'Ribulose-Bisphosphate Carboxylase', 'Ribulosephosphates', 'Sorghum'] | 26,508,521 | [['G16.500.275.157.100', 'N06.230.124.100'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['G05.400'], ['D01.268.604', 'D01.362.625'], ['D08.811.520.224.125.650'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.7... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Studies on the constituents of Calliandra anomala (Kunth) Macbr. III. Structure elucidation of six acylated triterpenoidal saponins. | Six new triterpenoidal saponins, called calliandra saponins G(1), H(2), I(3), J(4), K(5) and L(6), were isolated from the branches of Calliandra anomala (Kunth) Macbr. The structures of these compounds were established on the basis of NMR spectra, FAB-MS, and chemical evidence. These saponins, interestingly, have an N-... | ['Hydrolysis', 'Magnetic Resonance Spectroscopy', 'Mexico', 'Plant Extracts', 'Plants, Medicinal', 'Saponins', 'Spectrometry, Mass, Fast Atom Bombardment', 'Triterpenes'] | 8,681,414 | [['G02.380'], ['E05.196.867.519'], ['Z01.107.567.589'], ['D20.215.784.500', 'D26.667'], ['B01.650.560'], ['D09.408.782'], ['E05.196.566.750'], ['D02.455.849.919']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
The quantitative methods boot camp: teaching quantitative thinking and computing skills to graduate students in the life sciences. | The past decade has seen a rapid increase in the ability of biologists to collect large amounts of data. It is therefore vital that research biologists acquire the necessary skills during their training to visualize, analyze, and interpret such data. To begin to meet this need, we have developed a "boot camp" in quanti... | ['Biological Science Disciplines', 'Computational Biology', 'Humans', 'Students', 'Thinking'] | 25,880,064 | [['H01.158'], ['H01.158.273.180', 'L01.313.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.848'], ['F02.463.785']] | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
Dental disease prevention and people with special needs. | People with special needs are the most underserved of the underserved in our society. They have more dental disease, more missing teeth, and more difficulty obtaining dental care than other segments of the population. Many individuals and groups, including the authors of this paper, have developed community-based syste... | ['Adult', 'Aged', 'California', 'Communication Barriers', 'Community Health Planning', 'Congresses as Topic', 'Deinstitutionalization', 'Dental Care for Disabled', 'Dental Caries', 'Health Education, Dental', 'Health Services Accessibility', 'Humans', 'Intellectual Disability', 'Oral Hygiene', 'Periodontal Diseases'] | 12,636,320 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['L01.143.230'], ['N03.349.650.185'], ['N03.540.199'], ['E02.760.415.280', 'N02.421.585.415.280'], ['E06.170.310', 'N02.421.240.190.230'], ['C07.793.720.210'], ['I02.233.332.374', 'N02.421.726.407.457', 'N06.890.410'], ['N04.... | ['Named Groups [M]', 'Geographicals [Z]', 'Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Insulin is protein-anabolic in chronic renal failure patients. | To examine the protein anabolic actions of insulin in chronic renal failure, the authors measured four sets of whole body leucine fluxes during insulin alone and insulin with amino acid infusion in nine uremic patients before hemodialysis (B-HD). Seven were restudied 8 wk after initiation of maintenance hemodialysis (H... | ['Adolescent', 'Adult', 'Aged', 'Amino Acids', 'Anabolic Agents', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Electrolytes', 'Female', 'Glucose', 'Humans', 'Insulin', 'Kidney Failure, Chronic', 'Leucine', 'Male', 'Middle Aged', 'Parenteral Nutrition Solutions', 'Renal Dialysis', 'Solutions'] | 12,937,306 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.125'], ['D27.505.696.399.472.080'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['D01.248'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['C12.777.419.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An enzyme-linked immunosorbent assay (ELISA) for monitoring rodent colonies for Streptobacillus moniliformis antibodies. | An enzyme-linked immunosorbent assay (ELISA) to measure Streptobacillus moniliformis antibodies in mice and rats was developed. Twelve S. moniliformis strains originating from cases of rat-bite fever and Haverhill fever in man and from various rodent species, showed considerable serological relationship. The ELISA appe... | ['Animals', 'Antibodies, Bacterial', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Gram-Negative Bacterial Infections', 'Mice', 'Rats', 'Rats, Wistar', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Streptobacillus'] | 8,277,708 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['C01.150.252.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.99... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
In vitro regulation of local secretion and contraction of the bovine oviduct: stimulation by luteinizing hormone, endothelin-1 and prostaglandins, and inhibition by oxytocin. | The precise regulatory mechanisms of cyclic oviductal contraction in the cow are unclear. The purpose of this study was to evaluate the effect of luteinizing hormone (LH), steroids, prostaglandins (PGs) and peptides on the oviductal contraction and secretion of PGs and endothelin (ET-1). In addition, the cyclic express... | ['Analysis of Variance', 'Animals', 'Cattle', 'Dinoprost', 'Dinoprostone', 'Endothelin-1', 'Estrus', 'Fallopian Tubes', 'Female', 'Luteinizing Hormone', 'Microdialysis', 'Organ Culture Techniques', 'Oxytocin', 'Progesterone', 'RNA, Messenger', 'Receptors, Endothelin', 'Reverse Transcriptase Polymerase Chain Reaction', ... | 11,139,776 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D10.251.355.255.550.400.200', 'D23.469.050.175.725.400.200'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['D12.644.276.400.225', 'D12.776.467.400.225', 'D23.529.400.225'], ['G... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A new approach to aesthetic maxillofacial surgery: surgical treatment of unilateral exophthalmos due to maxillary sinus mucocele. | Maxillary sinus mucocele, known as a rare condition, can cause major therapeutic difficulties, especially when it invades the orbit leading to exophthalmia. Treatment is very difficult because the eye globe has to be repositioned, and the facial symmetry needs to be reconstructed as a result of malar bone invasion. Thi... | ['Biocompatible Materials', 'Bone Transplantation', 'Esthetics', 'Exercise Therapy', 'Exophthalmos', 'Follow-Up Studies', 'Humans', 'Male', 'Massage', 'Maxilla', 'Maxillary Sinus', 'Middle Aged', 'Mucocele', 'Orbital Diseases', 'Paranasal Sinus Diseases', 'Reconstructive Surgical Procedures', 'Surgical Flaps', 'Surgica... | 23,714,910 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['F02.463.785.477', 'K01.752.210'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['C11.675.349'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Fluorodeoxyuridine uptake by human colorectal hepatic metastases after hepatic artery infusion. | Tumor response rates after hepatic regional arterial chemotherapy infusion vary from 30% to 83% with little explanation for this variability. Drug clearance by the liver and plasma drug kinetics after arterial infusion have been described, but little is known about actual tumor drug uptake. This study measured fluorode... | ['Adenocarcinoma', 'Aged', 'Colonic Neoplasms', 'Female', 'Floxuridine', 'Hepatic Artery', 'Humans', 'Infusions, Intra-Arterial', 'Liver', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Radionuclide Imaging', 'Rectal Neoplasms', 'Technetium Tc 99m Aggregated Albumin', 'Time Factors'] | 2,943,036 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['D03.383.742.680.852.300.350', 'D13.570.230.430.432', 'D13.570.685.852.300.350'], ['A07.015.114.407'], ['B01.050.150.900.649.313.98... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Efficacy of platelet-rich plasma on wound healing in rabbits. | BACKGROUND: The purpose of this study was to evaluate if the healing of full-thickness skin wounds was accelerated by platelet-rich plasma (PRP).METHODS: Four 2.5 x 2.5-cm full-thickness skin wounds were created on the backs of 15 New Zealand white rabbits. One wound on each animal received 0.3, 0.6, or 0.9 ml PRP, and... | ['Animals', 'Cell Count', 'Cell Movement', 'Epithelium', 'Fibroblasts', 'Leukocyte Count', 'Macrophages', 'Male', 'Neovascularization, Physiologic', 'Neutrophils', 'Platelet-Rich Plasma', 'Rabbits', 'Random Allocation', 'Skin', 'Skin Diseases', 'Time Factors', 'Wound Healing'] | 18,380,563 | [['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.198', 'G07.568.500.180'], ['A10.272'], ['A11.329.228'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.195.107.595', 'G04.140.107.595', 'G09.188.105.595'], ['A... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The role of serotonin in the pathogenesis and clinical presentations of migraine attacks. | The Fontana-Masson method was used in 63 migraine patients to stain peripheral blood thrombocytes and measure the numbers of serotonin granules within them during the interictal period and, in 33 patients, during and 24, 48, and 72 h after migraine attacks. Enzyme-linked immunosorbent assay (ELISA) was used in 19 patie... | ['Adolescent', 'Adult', 'Blood Platelets', 'Case-Control Studies', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Migraine Disorders', 'Reference Values', 'Serotonin', 'Severity of Illness Index', 'Time Factors'] | 18,607,750 | [['M01.060.057'], ['M01.060.116'], ['A11.118.188', 'A15.145.229.188'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['M01.060.116.630'], ['C10.228... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo. | The tumor suppressor p53 is a potent inducer of tumor cell death, and strategies exist to exploit p53 for therapeutic gain. However, because about half of human cancers contain mutant p53, application of these strategies is restricted. p53 family members, in particular p73, are in many ways functional paralogs of p53, ... | ['Animals', 'Apoptosis', 'Cell Death', 'Cell Line, Tumor', 'DNA-Binding Proteins', 'Gene Expression Regulation, Neoplastic', 'Genes, p53', 'Humans', 'Mice', 'Mice, Knockout', 'Mice, Transgenic', 'Neoplasms', 'Nuclear Proteins', 'Transcriptional Activation', 'Tumor Protein p73', 'Tumor Suppressor Protein p53', 'Tumor Su... | 17,347,683 | [['B01.050'], ['G04.146.954.035'], ['G04.146'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.776.260'], ['G05.308.370'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415.400.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Canine dilated cardiomyopathy: a retrospective study of signalment, presentation and clinical findings in 369 cases. | OBJECTIVE: To review the clinical and diagnostic findings and survival of dilated cardiomyopathy from a large population of dogs in England.METHODS: A retrospective study of the case records of dogs with dilated cardiomyopathy collected between January 1993 and May 2006.RESULTS: There were 369 dogs with dilated cardiom... | ['Animals', 'Body Weight', 'Cardiomyopathy, Dilated', 'Dog Diseases', 'Dogs', 'Electrocardiography', 'England', 'Female', 'Male', 'Retrospective Studies', 'Risk Factors', 'Severity of Illness Index', 'Sex Factors', 'Survival Analysis'] | 19,037,887 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C14.280.195.160', 'C14.280.238.070', 'C16.320.488.750'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.370.380.240', 'E01.370.405.240'], ['Z01.542.363.300'], ['E05.3... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Establishment of age- and sex-adjusted reference data for hand bone mass and investigation of hand bone loss in patients with rheumatoid arthritis treated in clinical practice: an observational study from the DANBIO registry and the Copenhagen Osteoarthritis Study. | BACKGROUND: Rheumatoid arthritis is characterised by progressive joint destruction and loss of periarticular bone mass. Hand bone loss (HBL) has therefore been proposed as an outcome measure for treatment efficacy. A definition of increased HBL adjusted for age- and sex-related bone loss is lacking. In this study, we a... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'Bone Density', 'Denmark', 'Female', 'Hand Bones', 'Humans', 'Male', 'Middle Aged', 'Reference Values', 'Registries', 'Tumor Necrosis Factor-alpha', 'Young Adult'] | 26,912,229 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['G11.427.100'], ['Z01.542.816.124'], ['A02.835.232.087.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.978.810']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Spatial structure of gramicidin A in organic solvents. 1H-NMR analysis of conformation heterogeneity in ethanol]. | Structural features of double helices formed by polypeptides with alternating L- and D-amino acid residues were analysed. It was found that the map of short distances (less than 4 A) between protons of the two backbones is unique for each double helix type and even its fragment implies unambiguously parameters of the h... | ['Ethanol', 'Gramicidin', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Protein Conformation', 'Solvents'] | 2,450,545 | [['D02.033.375'], ['D04.345.566.850.300', 'D12.644.641.850.300', 'D12.776.543.695.221'], ['E05.196.867.519'], ['E05.599.595'], ['G02.111.570.820.709'], ['D27.720.844']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The NIMH Methods for the Epidemiology of Child and Adolescent Mental Disorders (MECA) Study: background and methodology. | OBJECTIVE: A collaborative study was conducted to develop methods for surveys of mental disorder and service utilization in unscreened population-based samples of children and adolescents.METHOD: Probability household samples of youths 9 through 17 years of age were selected at four sites and interviews were conducted ... | ['Adolescent', 'Adult', 'Child', 'Cross-Sectional Studies', 'Data Collection', 'Female', 'Health Surveys', 'Humans', 'Incidence', 'Male', 'Mental Disorders', 'National Institute of Mental Health (U.S.)', 'Personality Assessment', 'Research Design', 'Sampling Studies', 'United States'] | 8,768,345 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.40... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
[Specific immunotherapy in asthma]. | Specific immunotherapy (SIT) or allergenic desensitization would be the only treatment capable to change the natural history of the atopic march for children. SIT has shown numerous proofs of efficacy in allergic asthma particularly in improving clinical and medication scores. It could also have the capacity to prevent... | ['Asthma', 'Child', 'Desensitization, Immunologic', 'Humans', 'Immunotherapy', 'Treatment Outcome'] | 23,199,581 | [['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['M01.060.406'], ['E02.095.465.425.450.310', 'E05.478.610.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mutation of arginine residues to avoid non-specific cellular uptakes for hepatitis B virus core particles. | BACKGROUND: The hepatitis B virus core (HBc) particle is known as a promising new carrier for the delivery of drugs and nucleic acids. However, since the arginine-rich domain that is located in the C-terminal region of the HBc monomer binds to the heparan sulphate proteoglycan on the cell surface due to its positive ch... | ['Amino Acid Substitution', 'Arginine', 'Drug Carriers', 'Fluorescence', 'Glycine', 'HeLa Cells', 'Heparan Sulfate Proteoglycans', 'Hepatitis B virus', 'Humans', 'Microscopy, Atomic Force', 'Mutagenesis, Site-Directed', 'Mutation', 'Surface Plasmon Resonance'] | 25,890,025 | [['E05.393.420.601.035', 'G05.558.109'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D26.255.260', 'E02.319.300.380'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['D12.125.481'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['D09.698.373.425.500', 'D09.698.735.400', 'D12.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pixel-based OPC optimization based on conjugate gradients. | Optical proximity correction (OPC) methods are resolution enhancement techniques (RET) used extensively in the semiconductor industry to improve the resolution and pattern fidelity of optical lithography. In pixel-based OPC (PBOPC), the mask is divided into small pixels, each of which is modified during the optimizatio... | ['Algorithms', 'Computer Simulation', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Models, Theoretical'] | 21,369,034 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E05.599']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Changes in plasma levels of vasoactive substances during routine acetate and bicarbonate hemodialysis. | Hemodynamic stability is better preserved during bicarbonate hemodialysis compared to acetate. We have studied the effects of bicarbonate (HDB) and acetate hemodialysis (HDA) on plasma levels of vasoactive substances. The treatments were performed for 270 min. A cuprophan plate dialyzer was used. The ultrafiltration vo... | ['Acetates', 'Aged', 'Aged, 80 and over', 'Bicarbonates', 'Buffers', 'Female', 'Hemodialysis Solutions', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Neuropeptides', 'Renal Dialysis', 'Time Factors'] | 8,004,826 | [['D02.241.081.018', 'D10.251.400.045'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['D27.720.470.280'], ['D26.776.708.322.651', 'D27.505.954.578.483.651', 'D27.720.752.483.651'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Social networks and quality of life among female long-term colorectal cancer survivors. | BACKGROUND: The population of long-term colorectal cancer survivors in the United States continues to increase, but little is known about how they fare-physically, mentally, or socially-in the years after diagnosis. The current study examines female long-term colorectal cancer survivors' health-related quality of life ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Colorectal Neoplasms', 'Female', 'Health Status', 'Humans', 'Middle Aged', 'Quality of Life', 'Social Support', 'Survivors'] | 14,534,893 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.06... | ['Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Cell-specific expression of calcineurin immunoreactivity within the rat basolateral amygdala complex and colocalization with the neuropeptide Y Y1 receptor. | Neuropeptide Y (NPY) produces potent anxiolytic effects via activation of NPY Y1 receptors (Y1r) within the basolateral amygdaloid complex (BLA). The role of NPY in the BLA was recently expanded to include the ability to produce stress resilience and long-lasting reductions in anxiety-like behavior. These persistent be... | ['Amygdala', 'Animals', 'Calcineurin', 'Immunohistochemistry', 'Neurons', 'Rats', 'Rats, Sprague-Dawley', 'Rats, Wistar', 'Receptors, Neuropeptide Y', 'Signal Transduction'] | 22,884,996 | [['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['B01.050'], ['D08.811.277.352.650.625.150', 'D12.644.360.087', 'D12.776.476.087'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
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