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P2Y12 receptor inhibitors in patients with non-ST-elevation acute coronary syndrome in the real world: use, patient selection, and outcomes from contemporary European registries. | AIMS: Non-ST-elevation acute coronary syndrome (NSTE-ACS) is present in about 60-70% of patients admitted with acute coronary syndromes in clinical practice. This study provides a 'real-life' overview of NSTE-ACS patient characteristics, dual antiplatelet therapy clinical practice, and outcomes at both the time of disc... | ['Acute Coronary Syndrome', 'Adult', 'Aged', 'Aged, 80 and over', 'Drug Therapy, Combination', 'Europe', 'Female', 'Hemorrhage', 'Humans', 'Ischemia', 'Male', 'Middle Aged', 'Patient Selection', 'Platelet Aggregation Inhibitors', 'Purinergic P2Y Receptor Antagonists', 'Receptors, Purinergic P2Y12', 'Registries', 'Treat... | 27,533,946 | [['C14.280.647.124', 'C14.907.585.124'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.319.310'], ['Z01.542'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.513'], ['M01.060.116.630'], ['E05.581.500.653', 'N04.590.731'], ['D27.505.954.502.780'], ['D27.505.519.625.725... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Characteristics of skin cancers among adult patients in an urban Malaysian population. | There has been a rising incidence of skin cancers among Asians in recent years. We present a retrospective analysis of 106 skin cancers and analysed the demography, clinical subtypes of skin cancers and surgical techniques used for skin cancer treatment. In our population, skin cancers were most frequently basal cell c... | ['Aged', 'Aged, 80 and over', 'Carcinoma, Basal Cell', 'Carcinoma, Squamous Cell', 'Ethnic Groups', 'Female', 'Humans', 'Lymphoma, T-Cell, Cutaneous', 'Malaysia', 'Male', 'Middle Aged', 'Paget Disease, Extramammary', 'Retrospective Studies', 'Sarcoma, Kaposi', 'Sex Distribution', 'Skin Neoplasms', 'Urban Population'] | 31,222,718 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.165', 'C04.557.470.565.165'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['M01.686.754', 'N01.224.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480.750.800', 'C15.604.515.569.480.750.800', 'C20.683.515.761.480.750.800'], ['Z01... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Giant middle cerebral artery aneurysm with parent artery occlusion--case report. | A 54-year-old female was admitted with consciousness disturbance and right hemiparesis. Computed tomographic (CT) scans and angiograms revealed diffuse subarachnoid hemorrhage, a partially thrombosed, giant middle cerebral artery aneurysm (5 x 5 x 4 cm), and occlusion of the parent artery at the aneurysm site. Despite ... | ['Arterial Occlusive Diseases', 'Cerebral Angiography', 'Cerebral Infarction', 'Female', 'Humans', 'Intracranial Aneurysm', 'Middle Aged', 'Tomography, X-Ray Computed'] | 1,712,921 | [['C14.907.137'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.5... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Do Canadian prenatal records support evidence-based practices to reduce maternal smoking? | OBJECTIVES: Maternal smoking remains the most important modifiable risk factor for adverse perinatal outcomes. Integrating evidence-based screening questions and intervention guides for maternal smoking into standardized prenatal records may improve the identification and treatment of pregnant smokers. This study sough... | ['Adult', 'Canada', 'Counseling', 'Evidence-Based Medicine', 'Female', 'Humans', 'Mass Screening', 'Pregnancy', 'Prenatal Care', 'Smoking', 'Smoking Cessation', 'Smoking Prevention'] | 16,768,879 | [['M01.060.116'], ['Z01.107.567.176'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['H02.249.750', 'H02.403.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580'... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Muscle weakness following dynamic exercise in humans. | Electrical stimulation of the triceps surae in five healthy male subjects showed that following 1-2 h level running and uphill walking, at submaximal voltages of stimulation, exercise enhanced the twitch and tetanic responses, but the supramaximal time to peak tension (TPT), twitch (Pto) and tetanic tensions (Po) at 10... | ['Adult', 'Electric Stimulation', 'Electrophysiology', 'Humans', 'Leg', 'Male', 'Muscle Contraction', 'Physical Exertion'] | 7,118,637 | [['M01.060.116'], ['E05.723.402'], ['H01.158.344.528', 'H01.158.782.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['G11.427.494'], ['G11.427.683']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[Effects of duodenogastric bile reflux on gastric mucosal hexosamine concentrations after selective proximal vagotomy or extended distal gastrectomy for duodenal ulcer]. | Effects of duodenogastric reflux (DGR) of bile on hexosamine concentrations in gastric mucosa were studied in 17 healthy controls and 133 patients with duodenal ulcer patients before and after surgery. Total bile acid concentration in gastric juice was measured using enzyme method to estimate DGR. Mucosal hexosamine co... | ['Bile Acids and Salts', 'Duodenal Ulcer', 'Duodenogastric Reflux', 'Gastrectomy', 'Gastric Mucosa', 'Hexosamines', 'Humans', 'Vagotomy, Proximal Gastric'] | 3,393,126 | [['D04.210.500.105'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['C06.405.469.275.700', 'C06.405.748.240'], ['E04.210.419'], ['A03.556.875.875.440', 'A10.615.550.291'], ['D09.067.342'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.525.210.105.600.850.850']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The effect of the pH of the external solution on posttetanic hyperpolarization of a denuded nerve]. | A decrease in pH of the external solution from 7.3 to 5.3 causes an increase in post-tetanic hyperpolarization, while an increase in pH to 9 causes its decrease. The time-course of the hyperpolarization was increased at low pH and reduced at high pH. The possibility of a change in the electrogenicity of the sodium pum... | ['Animals', 'Biological Transport, Active', 'Cell Membrane Permeability', 'Electrophysiology', 'Hydrogen-Ion Concentration', 'Peripheral Nerves', 'Potassium', 'Sodium'] | 5,687 | [['B01.050'], ['G03.143.310'], ['G03.143.335', 'G04.175'], ['H01.158.344.528', 'H01.158.782.236'], ['G02.300'], ['A08.800.800'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['D01.268.549.750', 'D01.268.557.650', 'D01.552.528.850', 'D01.552.547.725']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Study of serial bronchoalveolar lavage in patients with aspergilloma: cell reaction at the affected sites and penetration of miconazole and flucytosine into the lesion]. | We have performed serial bronchoalveolar lavage (BAL) examination in two patients with asperigilloma and compared that of total cell count and cell population with control groups (5 non-smokers, 10 smokers) and other pulmonary infectious diseases: 7 each with mycoplasmal pneumonia and pulmonary tuberculosis, 6 with bac... | ['Administration, Oral', 'Adult', 'Aged', 'Aspergillosis', 'Bronchoalveolar Lavage Fluid', 'Female', 'Flucytosine', 'Humans', 'Infusions, Intravenous', 'Lung Diseases, Fungal', 'Male', 'Miconazole'] | 7,602,184 | [['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['C01.150.703.080'], ['E05.927.100.500'], ['D03.383.742.698.421.431'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['C01.150.703.534', 'C01.748.435', 'C08.381.472', 'C08.730.435'], ['D03.383.129.308.550']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Health status and return to work in trauma patients at 3 and 6 months post-discharge: an Australian major trauma centre study. | INTRODUCTION: The aim of this study was to describe post-discharge outcomes, and determine predictors of 3 and 6 months health status outcomes in a population of trauma patients at an inner city major trauma centre.METHODS: This was a prospective cohort study of adult trauma patients admitted to this hospital with 3 an... | ['Adult', 'Australia', 'Disabled Persons', 'Female', 'Follow-Up Studies', 'Health Status', 'Humans', 'Injury Severity Score', 'Male', 'Middle Aged', 'Patient Discharge', 'Prospective Studies', 'Quality of Life', 'Recovery of Function', 'Return to Work', 'Time Factors', 'Trauma Centers', 'Treatment Outcome', 'Wounds and... | 26,260,069 | [['M01.060.116'], ['Z01.639.100', 'Z01.678.100.373'], ['M01.150'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.940.968.875.500', 'E05.944.600', 'N04.452.85... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Humanities [K]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Roasted Barley Extract (Mugi-cha) Containing Cyclo(d-Phe-l-Pro) Prevents Lowering of the Cutaneous Blood Flow and Skin Temperature under Air Conditioning: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study. | Roasted barley extract (RBE), also known as mugi-cha, is a well-known healthy non-caffeinated beverage, and its health functionality has been widely reported. Our previous clinical study showed that RBE affects the cutaneous blood flow and skin temperature after cold-water immersion and that cyclo(d-Phe-l-Pro) is respo... | ['Adult', 'Air Conditioning', 'Blood Flow Velocity', 'Cross-Over Studies', 'Dipeptides', 'Double-Blind Method', 'Female', 'Food Handling', 'Hordeum', 'Hot Temperature', 'Humans', 'Male', 'Peptides, Cyclic', 'Placebos', 'Plant Extracts', 'Skin', 'Skin Temperature'] | 29,792,425 | [['M01.060.116'], ['N06.230.150.050'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D12.644.456.345'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['J01.576.423.200'], ['B01.650.940.800.575.912.250.822.481'], [... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Reducing post-traumatic anxiety by immunization. | Trafficking of T lymphocytes to specific organs, such as the skin and lungs, is part of the body's defense mechanism following acute psychological stress. Here we demonstrate that T lymphocytes are also trafficking to the brain in response to psychological stress and are needed to alleviate its negative behavioral cons... | ['Adaptation, Psychological', 'Animals', 'Anti-Inflammatory Agents', 'Anxiety', 'Behavior, Animal', 'Brain', 'Brain-Derived Neurotrophic Factor', 'Choroid Plexus', 'Corticosterone', 'Exploratory Behavior', 'Hippocampus', 'Immunization', 'Immunohistochemistry', 'Injections, Subcutaneous', 'Intercellular Adhesion Molecul... | 18,562,161 | [['F01.058'], ['B01.050'], ['D27.505.954.158'], ['F01.470.132'], ['F01.145.113'], ['A08.186.211'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['A08.186.211.140.298'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['F01.145.387', 'F01.658.370'], ['A08.186.211.... | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
The Role of Wnt/â-Catenin Signaling Pathway in the Transdifferentiation from Periodontal Ligament Stem Cells to Schwann Cells. | This study was aimed to investigate the role of Wnt/â-catenin signaling pathway in the differentiation from periodontal ligament stem cells (PDLSCs) to Schwann cells (SCs) and the possible mechanisms. FzB was applied to inhibit the Wnt/â-catenin signaling pathway of differentiated PDLSCs (dPDLSCs), and then immunofluor... | ['Animals', 'Cell Transdifferentiation', 'Dogs', 'Gene Expression Regulation, Developmental', 'Myelin Sheath', 'Organogenesis', 'Periodontal Ligament', 'Schwann Cells', 'Signal Transduction', 'Stem Cells', 'Wnt Proteins', 'beta Catenin'] | 29,215,941 | [['B01.050'], ['G04.356'], ['B01.050.150.900.649.313.750.250.216.200'], ['G05.308.310'], ['A08.637.600.500', 'A08.637.800.500', 'A08.675.542.512.560', 'A08.800.800.690.500', 'A10.755.503', 'A11.284.149.165.600', 'A11.650.600.500', 'A11.650.800.500', 'A11.671.501.512.560', 'A11.671.514.553'], ['G07.345.500.325.377', 'G0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Using discrete choice modelling in priority setting: an application to clinical service developments. | Limited resources for health care means that techniques are required to aid the process of priority setting. This paper represents one of the first attempts to use discrete choice modelling (DCM) within the area of priority setting. It is shown how the technique can be used to estimate cost per unit of benefit ratios f... | ['Adult', 'Aged', 'Attitude of Health Personnel', 'Budgets', 'Choice Behavior', 'Cost-Benefit Analysis', 'Decision Making, Organizational', 'Decision Support Techniques', 'Evidence-Based Medicine', 'Female', 'Health Care Rationing', 'Health Priorities', 'Humans', 'Male', 'Medical Staff, Hospital', 'Middle Aged', 'Needs... | 10,622,695 | [['M01.060.116'], ['M01.060.116.100'], ['F01.100.050', 'N05.300.100'], ['N03.219.463.060'], ['F02.463.785.373.346'], ['N03.219.151.125'], ['N04.452.190'], ['E05.245', 'L01.313.500.750.190'], ['H02.249.750', 'H02.403.200.400'], ['I01.261.750.500', 'N03.349.270', 'N05.300.430.375'], ['N03.349.330', 'N05.300.400'], ['B01.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Pm37, a new broadly effective powdery mildew resistance gene from Triticum timopheevii. | Powdery mildew is an important foliar disease in wheat, especially in areas with a cool or maritime climate. A dominant powdery mildew resistance gene transferred to the hexaploid germplasm line NC99BGTAG11 from T. timopheevii subsp. armeniacum was mapped distally on the long arm of chromosome 7A. Differential reaction... | ['Acrylic Resins', 'Alleles', 'Chromosome Mapping', 'Chromosomes, Plant', 'Expressed Sequence Tags', 'Genes, Plant', 'Genetic Markers', 'Genotype', 'Immunity, Innate', 'Physical Chromosome Mapping', 'Plant Diseases', 'Sequence Tagged Sites', 'Triticum'] | 18,092,148 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['G05.360.340.024.340.030'], ['E05.393.183'], ['A11.284.187.560', 'A18.005', 'G05.360.162.560'], ['G05.360.340.024.340.137.275'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['D23.101.387', 'G05.695.450'], ['G05.380'], ['G12.450.564... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Plasma exchange in the treatment of severe, childhood onset systemic lupus erythematosus. | Plasma exchange was used in the treatment of a 10-year-old girl with acute systemic lupus erythematosus. The patient was in a life-threatening condition, and treatment with high dose corticosteroids did not control the disease. The patient's condition improved dramatically during the second day of plasma exchange thera... | ['Child', 'Electroencephalography', 'Female', 'Humans', 'Lupus Erythematosus, Systemic', 'Plasma Exchange'] | 7,136,647 | [['M01.060.406'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.300.480', 'C20.111.590'], ['E02.095.135.750', 'E02.120.770.500', 'E02.912.715.500', 'E04.292.869.500']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Technology Part III: exploiting the opportunities. | This is the third article in a three-part series about technology and its impact on healthcare systems and the business of health care. The first article highlighted the use of the Internet. The second article explored new technologies that are changing clinical health care and creating new opportunities for healthcare... | ['Complementary Therapies', 'Delivery of Health Care', 'Efficiency, Organizational', 'Health Maintenance Organizations', 'Internet', 'Marketing of Health Services', 'Medical Laboratory Science'] | 10,977,417 | [['E02.190'], ['N04.590.374', 'N05.300'], ['N04.452.209.500'], ['N03.219.521.576.343.800.400', 'N03.219.521.576.343.925.400', 'N04.452.758.244.425', 'N04.590.374.410.400'], ['L01.224.230.110.500'], ['J01.219.687.550', 'N03.219.463.548', 'N05.300.430.500'], ['H02.010.450', 'J01.897.480']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
The 45 pocket of HLA-A2.1 plays a role in presentation of influenza virus matrix peptide and alloantigens. | Amino acid substitutions were introduced into the 45 pocket of HLA-A2.1 to determine the potential role of this structurally defined feature of class I molecules in viral peptide and alloantigen presentation. The 45 pocket lies below the alpha 1-domain alpha-helix and is composed of five amino acids, three of which dif... | ['Base Sequence', 'Gene Products, tax', 'HLA-A Antigens', 'Humans', 'Influenza A virus', 'Isoantigens', 'Models, Molecular', 'Molecular Sequence Data', 'Mutation', 'Structure-Activity Relationship', 'T-Lymphocytes, Cytotoxic', 'Transfection', 'Viral Matrix Proteins'] | 2,026,879 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.624.664.520.750.480', 'D12.776.964.700.750.480', 'D12.776.964.775.750.480', 'D12.776.964.925.984.410'], ['D12.776.395.550.489.400', 'D12.776.543.550.439.400', 'D23.050.301.500.100.400', 'D23.050.301.500.450.370', 'D23.050.705.552.100.400', 'D23.050.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Yi Qi Qing Re Gao formula ameliorates puromycin aminonucleoside-induced nephrosis by suppressing inflammation and apoptosis. | BACKGROUND: Yi Qi Qing Re Gao (YQQRG) formula is a traditional Chinese herbal medicine used to treat chronic nephritis. This study was designed to evaluate the underlying mechanism in the use of YQQRG formula to treat nephrosis induced by puromycin aminonucleoside (PAN).METHODS: Thirty-six male Wistar rats were randoml... | ['Animals', 'Anti-Inflammatory Agents', 'Apoptosis', 'Caspase 3', 'Drugs, Chinese Herbal', 'Immunohistochemistry', 'Inflammation', 'Kidney', 'Male', 'Microscopy, Electron, Transmission', 'Nephritis', 'Nephrosis', 'Phytotherapy', 'Puromycin Aminonucleoside', 'Qi', 'RNA, Messenger', 'Rats, Wistar', 'Real-Time Polymerase ... | 26,014,479 | [['B01.050'], ['D27.505.954.158'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D20.215.784.500.350', 'D26.335'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Dilator and constrictor response of renal vasculature during acute renal hypotension in anesthetized goats. Role of nitric oxide. | The relative role of NO derived from endothelium NO synthase (eNOS) and neuronal NO synthase (nNOS) in renovascular reactivity during renal hypotension is unknown. To examine this issue, we recorded the effects of unspecific inhibitor of NO synthase N(w)-nitro-L-arginine methyl esther (L-NAME) and inhibitor of nNOS 7-n... | ['Acetylcholine', 'Animals', 'Aorta, Abdominal', 'Female', 'Goats', 'Hypotension', 'Indazoles', 'Kidney', 'NG-Nitroarginine Methyl Ester', 'Nitric Oxide', 'Nitric Oxide Synthase Type I', 'Nitric Oxide Synthase Type III', 'Nitroprusside', 'Renal Artery', 'Vasoconstriction', 'Vasodilation'] | 21,571,096 | [['D02.092.211.111'], ['B01.050'], ['A07.015.114.056.205'], ['B01.050.150.900.649.313.500.380.513'], ['C14.907.514'], ['D03.383.129.539.487', 'D03.633.100.449'], ['A05.810.453'], ['D12.125.068.050.525', 'D12.125.095.104.525'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['D08.811.682.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunomodulation in the treatment of malignant disorders. | In this study, 91 patients with metastatic solid tumor were treated with an immunomodulatory regimen of interferons -a and -g as well as octreide in pulse administration, followed in selected patients by low dose perilymphatic administration of interleukin-2. Pharmacosensitivity studies of patient tumor directed concom... | ['Drug Administration Schedule', 'Female', 'Humans', 'Immunotherapy', 'Interferons', 'Interleukin-2', 'Male', 'Middle Aged', 'Neoplasms', 'Octreotide'] | 7,508,679 | [['E02.319.283'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425'], ['D12.644.276.374.440', 'D12.776.467.374.440', 'D23.529.374.440'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.776.467.374.480.372', 'D23.529.374.465.155', 'D23.529.374.480.372'], ['M01.060... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Primary repair of colon injuries: clinical study of nonselective approach. | BACKGROUND: This study was designed to determine the role of primary repair and to investigate the possibility of expanding indications for primary repair of colon injuries using nonselective approach.METHODS: Two groups of patients were analyzed. Retrospective (RS) group included 30 patients managed by primary repair ... | ['Adult', 'Colon', 'Digestive System Surgical Procedures', 'Female', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prospective Studies', 'Retrospective Studies', 'Trauma Severity Indices', 'Treatment Outcome', 'Wounds, Penetrating', 'Young Adult'] | 21,126,337 | [['M01.060.116'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['E04.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The dietary therapy of diabetes. | The basis of different diets for insulin dependent and maturity onset obese diabetics is discussed. The results achieved by strict calorie control in obese diabetics are compared with those in a group of patients with simple obesity and shown to be superior. The value of very low carbohydrate lager is assessed. It is c... | ['Alcoholic Beverages', 'Diabetes Mellitus', 'Diet, Diabetic', 'Dietary Carbohydrates', 'Humans', 'Obesity'] | 482,194 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
External and computed tomography analysis of a strophocephalic lamb. | CONTEXT: The Museum of Anatomy and Embryology Louis Deroubaix attached to the Laboratory of Anatomy, Biomecanics and Organogenesis, ULB, Brussels, possesses in its liquid collections a cephalic extremity of a lamb suffering from strophocephaly. The origins have not been determined. The trunk and the limbs are resected.... | ['Animals', 'Craniofacial Abnormalities', 'Head', 'Holoprosencephaly', 'Sheep', 'Tomography, X-Ray Computed'] | 30,853,367 | [['B01.050'], ['C05.660.207', 'C16.131.621.207'], ['A01.456'], ['C05.660.207.410', 'C10.500.034.875', 'C16.131.077.410', 'C16.131.260.380', 'C16.131.621.207.410', 'C16.131.666.034.875', 'C16.320.180.380'], ['B01.050.150.900.649.313.500.380.791'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.7... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of protein kinase chk1 essential for the cell cycle checkpoint after exposure of human head and neck carcinoma A253 cells to a novel topoisomerase I inhibitor BNP1350. | Cellular topoisomerase I is an important target in cancer chemotherapy. A novel karenitecin, BNP1350, is a topoisomerase I-targeting anticancer agent with significant antitumor activity against human head and neck carcinoma A253 cells in vitro. As a basis for future clinical trials of BNP1350 in human head and neck car... | ['CDC2 Protein Kinase', 'Camptothecin', 'Cell Cycle', 'Cell Cycle Proteins', 'Cell Division', 'Checkpoint Kinase 1', 'Cyclin B', 'DNA Fragmentation', 'DNA Topoisomerases, Type I', 'Electrophoresis, Gel, Pulsed-Field', 'Head and Neck Neoplasms', 'Humans', 'Phosphorylation', 'Protein Kinases', 'Topoisomerase I Inhibitors... | 10,692,484 | [['D08.811.913.696.620.682.700.646.500.500.250', 'D08.811.913.696.620.682.700.646.500.984.500', 'D12.644.360.250.067.249', 'D12.644.360.250.580.500', 'D12.776.167.200.067.249', 'D12.776.167.200.580.500', 'D12.776.476.250.067.249', 'D12.776.476.250.580.500', 'D12.776.744.360'], ['D03.132.151'], ['G04.144'], ['D12.776.16... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Risk of death or acute myocardial infarction 10 years after coronary artery bypass surgery in relation to type of diabetes. | BACKGROUND: The aim of this study was to assess the long-term risk of death or acute myocardial infarction (AMI) in patients with diabetes mellitus (DM) compared with that in patients without DM after coronary artery bypass grafting (CABG).METHODS: National registers were used to record death or AMI occurring in 6727 p... | ['Adult', 'Aged', 'Cause of Death', 'Coronary Artery Bypass', 'Diabetes Mellitus, Type 1', 'Diabetes Mellitus, Type 2', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Registries', 'Retrospective Studies', 'Risk Factors'] | 16,923,437 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.394.750.149', 'C19.246.300'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Infection prevention in Dutch hospitals; results say more than process indicators]. | The Dutch Health Care Inspectorate investigated the preparedness of Dutch hospitals for the emergence of antibiotic resistance, and concluded that hospitals are not well prepared and are insufficiently aware that infection prevention is a prerequisite for patient safety. These conclusions are based on observations of p... | ['Cross Infection', 'Delivery of Health Care', 'Drug Resistance, Bacterial', 'Hospitals', 'Humans', 'Quality of Health Care'] | 24,594,133 | [['C01.248', 'C23.550.291.875.500'], ['N04.590.374', 'N05.300'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761', 'N05.715']] | ['Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Daily rhythmic expression patterns of clock1a, bmal1, and per1 genes in retina and hypothalamus of the rainbow trout, Oncorhynchus mykiss. | Living organisms show daily rhythms in physiology, behavior, and gene expression, which are due to the presence of endogenous clocks that synchronize biological processes to the 24-h light/dark cycle. In metazoans, generation of circadian rhythmicity is a consequence of specialized tissues known as "master clocks," hav... | ['ARNTL Transcription Factors', 'Amino Acid Sequence', 'Animals', 'Base Sequence', 'CLOCK Proteins', 'Circadian Rhythm', 'DNA, Complementary', 'Gene Expression Regulation', 'Hypothalamus', 'Molecular Sequence Data', 'Oncorhynchus mykiss', 'Period Circadian Proteins', 'Retina'] | 21,721,853 | [['D12.644.360.138.049', 'D12.776.260.103.249', 'D12.776.476.156.100', 'D12.776.930.125.249'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.913.050.134.415.500.049', 'D12.644.360.138.100', 'D12.776.260.103.562', 'D12.776.476.156.200', 'D12... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Acquired distance esotropia associated with myopia. | BACKGROUND: Von Graefe (1864)(1) and Bielschowsky (1922)(2) described acquired progressive esotropia, with typically a larger angle for distance than near, associated with moderate myopia. This is unlike the esotropia seen in patients with high myopia.METHODS: We reviewed our patient records, finding 26 cases: 14 were ... | ['Adult', 'Aged', 'Botulinum Toxins, Type A', 'Diplopia', 'Esotropia', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myopia', 'Neuromuscular Agents', 'Oculomotor Muscles'] | 15,370,522 | [['M01.060.116'], ['M01.060.116.100'], ['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['C10.597.751.941.339', 'C11.966.339', 'C23.888.592.763.941.339'], ['C10.292.562.887.300', 'C11.590.810.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Bioinformatics characterization of envelope glycoprotein from Kyasanur Forest disease virus. | Background & objectives: Kyasanur Forest disease (KFD) is a febrile illness characterized by haemorrhages and caused by KFD virus (KFDV), which belongs to the Flaviviridae family. It is reported to be an endemic disease in Shimoga district of Karnataka State, India, especially in forested and adjoining areas. Several o... | ['Computational Biology', 'Disease Outbreaks', 'Encephalitis Viruses, Tick-Borne', 'Endemic Diseases', 'Glycoproteins', 'Humans', 'India', 'Kyasanur Forest Disease', 'Viral Envelope Proteins'] | 29,806,609 | [['H01.158.273.180', 'L01.313.124'], ['N06.850.290'], ['B04.820.230.511', 'B04.820.578.344.350.350'], ['N06.850.392'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['C01.920.930.475', 'C01.925.081.656', 'C01.925.782.350.250.635', 'C01.925.782.417.475'], ['D09.400... | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy. | Suppression of the host's immune system plays a major role in cancer progression. Tumor signaling of programmed death 1 (PD1) on T cells and expansion of myeloid-derived suppressor cells (MDSCs) are major mechanisms of tumor immune escape. We sought to target these pathways in rhabdomyosarcoma (RMS), the most common so... | ['Adolescent', 'Adult', 'Animals', 'Antibodies, Monoclonal', 'Antigens, Ly', 'Antineoplastic Combined Chemotherapy Protocols', 'B7-H1 Antigen', 'CD11b Antigen', 'Case-Control Studies', 'Cell Line, Tumor', 'Chemokine CXCL1', 'Chemotaxis', 'Child', 'Child, Preschool', 'Cytokines', 'Female', 'Humans', 'Interleukin-8', 'Ma... | 24,848,257 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264.920', 'D23.101.100.920'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D12.776.465.625', 'D12.776.467.150.300', 'D12.776.543.095.300', 'D23.050... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[A prospective trial of hemodilution therapy in acute cerebral infarction]. | Ninety two 50-year-old-or-more patients with acute (less than 72 hours) cerebral infarction involved middle cerebral artery region and hematocrit of 40% or more were prospectively randomised to either hemodilution group (by rapid venesection, venous infusion of autologous plasma and 500 ml dextran 40) or standard thera... | ['Acute Disease', 'Aged', 'Blood Viscosity', 'Bloodletting', 'Cerebral Infarction', 'Dextrans', 'Female', 'Hematocrit', 'Hemodilution', 'Humans', 'Male', 'Middle Aged', 'Plasmapheresis', 'Prospective Studies'] | 1,382,927 | [['C23.550.291.125'], ['M01.060.116.100'], ['G09.188.370.124', 'G09.330.380.630.110'], ['E02.800.558.500'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['D05.750.078.562.272', 'D09.698.365.272... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Managing variations from surgical care plans: challenges for coordination. | INTRODUCTION: In surgical work there is a need for 'continuous planning' among staff to handle the frequently occurring variations from the planned patient treatment. In this paper, we present how three hospital information systems have support for three common patient trajectory variations.PURPOSE: Highlight how devia... | ['Computer Systems', 'Delivery of Health Care', 'Health Services Needs and Demand', 'Hospital Information Systems', 'Humans', 'Interdisciplinary Communication', 'Patient Care Planning', 'Surgical Procedures, Operative'] | 22,975,017 | [['L01.224.230'], ['N04.590.374', 'N05.300'], ['N03.349.380.420', 'N05.300.450'], ['N04.452.442.452.452', 'N04.452.515.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205.249', 'L01.143.865.500'], ['N04.590.233.624'], ['E04']] | ['Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Stress and reward: long term cortisol exposure predicts the strength of sexual preference. | Healthy individuals tend to consume available rewards like food and sex. This tendency is attenuated or amplified in most stress-related psychiatric conditions, so we asked if it depends on endogenous levels of the 'canonical stress hormone' cortisol. We unobtrusively quantified how hard healthy heterosexual men would ... | ['Adolescent', 'Adult', 'Anhedonia', 'Hair', 'Humans', 'Hydrocortisone', 'Linear Models', 'Male', 'Neuropsychological Tests', 'Photic Stimulation', 'Reward', 'Sexual Behavior', 'Visual Perception', 'Young Adult'] | 24,732,415 | [['M01.060.057'], ['M01.060.116'], ['C10.597.606.057', 'C23.888.592.604.039', 'F01.700.039'], ['A17.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.36... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mimotopes of mutalysin-II from Lachesis muta snake venom induce hemorrhage inhibitory antibodies upon vaccination of rabbits. | Mutalysin-II (mut-II) from Lachesis muta snake venom is an endopeptidase with hemorrhagic activity. A mAb against mutalysin-II that neutralized the hemorrhagic effect was produced previously. To identify the mAb epitopes, sets of 15-mer overlapping peptides covering the mut-II amino acid sequence were synthesized using... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal', 'Crotalid Venoms', 'Epitopes', 'Female', 'Hemorrhage', 'Metalloendopeptidases', 'Molecular Sequence Data', 'Peptide Library', 'Peptides', 'Rabbits', 'Vaccination'] | 21,763,377 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D20.888.850.960.200', 'D23.946.833.850.960.200'], ['D23.050.550'], ['C23.550.414'], ['D08.811.277.656.300.480', 'D08.811.277.656.675.374'], ['L01.453.245.667'], ['D1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Pyoderma gangrenosum occurring in a lower limb fasciocutaneous flap--a lesson to learn. | Pyoderma gangrenosum is a destructive cutaneous disease characterised by progressive painful ulceration. The occurrence of pyoderma gangrenosum at a surgical site is rare (especially if there is no predisposing illness), but is well recognised. We present a case of a 63-year-old man who developed erythematous ulcerativ... | ['Anti-Inflammatory Agents', 'Arthroplasty, Replacement, Knee', 'Biopsy', 'Diagnosis, Differential', 'Humans', 'Male', 'Middle Aged', 'Prednisolone', 'Pyoderma Gangrenosum', 'Surgical Wound Infection'] | 10,876,286 | [['D27.505.954.158'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D04... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Multidrug-resistant Mycobacterium tuberculosis in an HIV dental clinic. | OBJECTIVE: To investigate possible transmission of multidrug-resistant tuberculosis (MDR-TB) in a dental setting.DESIGN: A retrospective, descriptive study of dental workers (DWs), patients, and practice characteristics.PATIENTS: Two dental workers (DW1 and DW2) with acquired immunodeficiency syndrome and MDR-TB.SETTIN... | ['Acquired Immunodeficiency Syndrome', 'Antitubercular Agents', 'Dental Clinics', 'Dental Staff, Hospital', 'Humans', 'Infection Control', 'Mycobacterium tuberculosis', 'New York City', 'Retrospective Studies', 'Tuberculosis, Multidrug-Resistant'] | 7,897,177 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['D27.505.954.122.085.255'], ['N02.278.192.250'], ['M01.526.485.290.490', 'M01.526.485.740.322', 'N02.360.290.490', 'N02.360.740.322'], ['B01.050.150.90... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
In vitro response of lymphocytes in patients with allergic tension-fatigue syndrome. | The authors studied the stimulation of lymphocytes in 44 patients with histories of allergic tension-fatigue syndrome using a series of food extracts and additives. Of a total of 44 patients studied, 42 produced a positive response (RI), 18.1% produced a positive response to additives, 40.9% to food and 36.6% to both. ... | ['Child', 'Child, Preschool', 'Female', 'Food Additives', 'Food Hypersensitivity', 'Humans', 'Hypersensitivity', 'Lymphocyte Activation', 'Male', 'Mental Fatigue', 'Stress, Psychological', 'Syndrome'] | 6,106,442 | [['M01.060.406'], ['M01.060.406.448'], ['D27.720.372.300', 'G07.203.300.514.500', 'J02.500.514.500'], ['C20.543.480.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ['C23.888.369.500', 'F01.145.126.937']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Competitive sorption and desorption of trace elements by Tunisian Aridisols Calcorthids. | The sorption and retention processes play an important role in determining the bioavaibility and fate of trace elements in soils. Sorption and desorption of Pb(2+), Zn(2+), Ni(2+), Cu(2+), and Co(2+) in three Tunisian Aridisols Calcorthids (AR1, AR2, and AR3) were studied using batch experiments. Sorption and retention... | ['Adsorption', 'Aluminum Silicates', 'Clay', 'Ferric Compounds', 'Soil', 'Soil Pollutants', 'Trace Elements', 'Tunisia'] | 25,772,874 | [['G01.030', 'G02.020'], ['D01.056.050.075', 'D01.578.725.025', 'D01.650.550.050.075', 'D01.837.725.700.760.050'], ['D20.721.250', 'G01.311.820.250', 'G16.500.275.815.250', 'N06.230.600.250'], ['D01.490.100'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D27.888.284.756'], ['D01.268.811', 'D27.505.69... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
A comprehensive evolutionary analysis based on nucleotide and amino acid sequences of the alpha- and beta-subunits of glycoprotein hormone gene family. | On the basis of nucleotide sequences of the coding region and their predicted amino acid sequences, 58 glycoprotein hormone subunit genes were compared, aligned and used to construct phylogenetic trees for this family. The analysis included 17 alpha-subunits, eight TSH beta-, six FSH beta-, 17 LH beta/CG beta-, four fi... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Chorionic Gonadotropin, beta Subunit, Human', 'Evolution, Molecular', 'Fishes', 'Follicle Stimulating Hormone', 'Follicle Stimulating Hormone, beta Subunit', 'Glycoprotein Hormones, alpha Subunit', 'Gonadotropins, Pituitary', 'Horses', 'Humans', 'Luteinizing Hormone'... | 9,582,510 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D06.472.699.322.326.125', 'D06.472.699.649.367.125', 'D12.644.548.726.367.125', 'D12.776.780.400.125', 'D23.101.140.325', 'D23.101.175'], ['G05.045.250', 'G16.075.250'], ['B01.050.150.900.493'], ['D06.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
In vitro levels of cytokines in response to purified protein derivative (PPD) antigen in a population with high prevalence of pulmonary tuberculosis. | The control of mycobacterial infection by the host depends on cell-mediated immunity (CMI), involving activated macrophages, T cells, and type 1 cytokines (Th1). Here we evaluated the capacity of antigen-induced proliferation by peripheral blood mononuclear cells (PBMCs) and the production of proinflammatory tumor necr... | ['Adult', 'Cell Proliferation', 'Cytokines', 'Female', 'Humans', 'Leukocytes, Mononuclear', 'Lymphocyte Activation', 'Male', 'Middle Aged', 'Mycobacterium tuberculosis', 'Population Groups', 'Prevalence', 'Th1 Cells', 'Th1-Th2 Balance', 'Th2 Cells', 'Tuberculin', 'Tuberculosis, Pulmonary', 'Venezuela'] | 20,650,294 | [['M01.060.116'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555', 'A15.145.229.637.555', 'A15.382.490.555'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565']... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Gingival displacement: Survey results of dentists' practice procedures. | STATEMENT OF PROBLEM: A high percentage of fixed prosthodontic restorations require a subgingival margin placement, which requires the practice of gingival displacement or a deflection procedure to replicate the margins in impression.PURPOSE: The purpose of this study was to learn the different gingival displacement te... | ['Alum Compounds', 'Aluminum Chloride', 'Aluminum Compounds', 'Anxiety', 'Arrhythmias, Cardiac', 'Astringents', 'Blood Pressure', 'Chlorides', 'Clinical Competence', 'Electrosurgery', 'Epinephrine', 'Ferric Compounds', 'General Practice, Dental', 'Gingival Retraction Techniques', 'Heart Rate', 'Humans', 'Hypertension',... | 25,917,854 | [['D01.056.025', 'D01.875.800.800.850.025'], ['D01.056.031', 'D01.210.450.150.025'], ['D01.056'], ['F01.470.132'], ['C14.280.067', 'C23.550.073'], ['D27.505.696.207', 'D27.505.954.444.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D01.210.450.150', 'D01.248.497.158.215'], ['I02.399.630.210', 'N04.761.210', 'N05.7... | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Vitamin E in neural and visual function. | A rat model of vitamin E (alpha-tocopherol) deficiency with similar "clinical," electrophysiological, and neuropathological abnormalities to those seen in man was used to investigate the effects of various amounts and forms of alpha-tocopheryl acetate (alphaTA) on neural and visual function. Electrophysiological techni... | ['Animals', 'Diet', 'Electroretinography', 'Evoked Potentials, Somatosensory', 'Evoked Potentials, Visual', 'Lipid Peroxidation', 'Male', 'Malondialdehyde', 'Nervous System Diseases', 'Nutritional Requirements', 'Oxidative Stress', 'Rats', 'Rats, Wistar', 'Vision Disorders', 'Vitamin E', 'Vitamin E Deficiency', 'alpha-... | 15,753,152 | [['B01.050'], ['G07.203.650.240'], ['E01.370.380.225', 'E01.370.405.270'], ['G07.265.216.500.400', 'G11.561.200.500.400'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['G02.111.515', 'G03.295.531.587'], ['D02.047.700'], ['C10'], ['G07.203.650.620'], ['G03.673', 'G07.775.750'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Caffeine metabolism in liver slices during postnatal development in rats. | The metabolism of caffeine was investigated in liver slices from newborn, preweanling, postweanling, and adult rats. All metabolites were identified and quantified by HPLC without using radioactive compound. Caffeine metabolism underwent dramatic changes during maturation in rats. The specific activity of the enzyme sy... | ['Animals', 'Biotransformation', 'Caffeine', 'Chromatography, High Pressure Liquid', 'Liver', 'Male', 'Methylation', 'Rats', 'Rats, Sprague-Dawley', 'Theobromine', 'Theophylline', 'Uracil'] | 8,095,214 | [['B01.050'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['E05.196.181.400.300'], ['A03.620'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['D03.132.960.651', ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adaptation of proteases and carbohydrates of saprophytic, phytopathogenic and entomopathogenic fungi to the requirements of their ecological niches. | The abilities of isolates of saprophytes (Neurospora crassa, Aspergillus nidulans), an opportunistic human pathogen (Aspergillus fumigatus), an opportunistic insect pathogen (Aspergillus flavus), plant pathogens (Verticillium albo-atrum, Verticillium dahliae, Nectria haematococca), a mushroom pathogen (Verticillium fun... | ['Adaptation, Physiological', 'Animals', 'Aspergillus', 'Aspergillus nidulans', 'Carbohydrates', 'Ecology', 'Endopeptidases', 'Enzymes', 'Fungal Proteins', 'Fungi', 'Growth Substances', 'Insecta', 'Mitosporic Fungi', 'Neurospora crassa', 'Polysaccharides', 'Protease Inhibitors', 'Substrate Specificity'] | 9,202,474 | [['G07.025', 'G16.012.500'], ['B01.050'], ['B01.300.381.081'], ['B01.300.381.081.420'], ['D09'], ['H01.158.273.248', 'H01.277.249'], ['D08.811.277.656.300'], ['D08.811'], ['D12.776.354'], ['B01.300'], ['D27.505.696.377'], ['B01.050.500.131.617'], ['B01.300.381'], ['B01.300.107.800.629.564'], ['D09.698'], ['D27.505.519.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Exposure to xylene and ethylbenzene. I. Uptake, distribution and elimination in man. | Industrial xylene is a mixture of xylene and ethylbenzene. Twelve male subjects were exposed to industrial xylene in inspired air, six subjects in series I to 870 mg/m3 at rest (30 min) and light exercise on a bicycle ergometer (90 min) and six subjects in series II to 435 mg/m3 at rest (30 min) and during exercise of ... | ['Adult', 'Air', 'Air Pollutants', 'Air Pollutants, Occupational', 'Benzene Derivatives', 'Environmental Exposure', 'Hemodynamics', 'Humans', 'Male', 'Physical Exertion', 'Respiratory Function Tests', 'Time Factors', 'Tissue Distribution', 'Xylenes'] | 705,285 | [['M01.060.116'], ['G16.500.275.063.150', 'N06.230.300.100.150'], ['D27.888.284.101'], ['D27.888.284.101.268'], ['D02.455.426.559.389'], ['N06.850.460.350'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.683'], ['E01.370.386.700'], ['G01.910.857'], ['G03.787.917', 'G07.690.725.949'], ['D02... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cytochrome P450 expression and catalytic activity in coronary arteries and liver of cattle. | There is increasing evidence that cytochrome P450 (CYP) enzymes are involved not only in the metabolism of xenobiotics, but also in vascular homeostasis. Among the CYP-derived vasoactive agents, special importance is assigned to endogenous products from arachidonic acid (AA). Specifically, the vasodilator epoxyeicosatr... | ['Amino Acid Sequence', 'Animals', 'Cattle', 'Coronary Vessels', 'Cytochrome P-450 Enzyme System', 'DNA Primers', 'Isoenzymes', 'Liver', 'Microsomes, Liver', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Sequence Alignment', 'Sequence Homology, Amino Acid', 'Sequence Homology, Nucleic Acid', 'Sheep'] | 15,716,024 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A07.015.114.269', 'A07.015.908.194'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D08.811.348', 'D12.776.800.300'], ['A03.620'], ['A11... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A bio-psychosocial evaluation of ten adolescents with fibromyalgia. | A comprehensive assessment of 10 adolescents (mean age 15.7 years) fulfilling the ACR criteria for fibromyalgia, disclosed that 3 patients also had juvenile chronic arthritis. Based on semi-structured psychiatric interviews, testing and family assessments, 6 of the patients had a psychiatric diagnosis (over anxious and... | ['Adolescent', 'Anxiety Disorders', 'Arthritis, Juvenile', 'Case-Control Studies', 'Child', 'Counseling', 'Depressive Disorder', 'Educational Status', 'Family', 'Female', 'Fibromyalgia', 'Humans', 'Intelligence', 'Interview, Psychological', 'Male', 'Pain', 'Pain Measurement', 'Pilot Projects', 'Referral and Consultatio... | 7,949,810 | [['M01.060.057'], ['F03.080'], ['C05.550.114.122', 'C05.799.056', 'C17.300.775.049', 'C20.111.198'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['F03.600.300'], ['N01.824.196'], ['F01.829.263', 'I0... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Attitudes and practices of families of children in treatment for cancer. A cross-cultural study. | A follow-up study was made of the prevalence of the use of unproven treatment methods by families of children being treated for cancer at UT M.D. Anderson Hospital. Information was also obtained about parental attitudes toward conventional and alternative treatments and their understanding of them, as well as the physi... | ['Adult', 'Attitude to Health', 'Child', 'Complementary Therapies', 'Cross-Cultural Comparison', 'European Continental Ancestry Group', 'Family', 'Female', 'Hispanic Americans', 'Humans', 'Male', 'Neoplasms', 'Physician-Patient Relations'] | 6,859,456 | [['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['M01.060.406'], ['E02.190'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['M01.686.508.400'], ['F01.829.263', 'I01.880.853.150'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['F01.829.401.650.675', 'N05.300.660.625']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A systematic assessment of the quality of reporting for platelet transfusion studies. | BACKGROUND: As evidence-based medicine assumes increasing importance, there is a need for high-quality reporting of clinical studies. A recent review of clinical platelet (PLT) studies indicated variability in reporting. We undertook a critical analysis of PLT transfusion studies to determine the quality of reporting.S... | ['Humans', 'Platelet Transfusion', 'Publishing', 'Randomized Controlled Trials as Topic'] | 20,497,518 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.135.140.650'], ['L01.737'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365.500']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs. | Members of the family of Ras-related guanosine triphosphate (GTP) binding proteins appear to take part in the regulation of a number of biological processes, including cell growth and differentiation. Three different classes of proteins that regulate the GTP binding and GTP hydrolytic activities of the Ras family membe... | ['Animals', 'Blood Platelets', 'Brain Chemistry', 'Cattle', 'Escherichia coli', 'GTP Phosphohydrolases', 'GTP-Binding Proteins', 'GTPase-Activating Proteins', 'Guanine Nucleotide Dissociation Inhibitors', "Guanosine 5'-O-(3-Thiotriphosphate)", 'Guanosine Diphosphate', 'Guanosine Triphosphate', 'Hydrolysis', 'Membrane P... | 1,439,791 | [['B01.050'], ['A11.118.188', 'A15.145.229.188'], ['G02.111.150', 'G03.185'], ['B01.050.150.900.649.313.500.380.271'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D08.811.277.040.330'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['D12.644.360.325.150', 'D12.776.476.325.150'], ['D12.644.360.325.225', ... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nanoscale in situ morphological study of proteins immobilized on gold thin films. | The nanoscale organization of acetylcholinesterase (AChE) and of its polyclonal antibody immobilized on gold thin films was studied by means of Energy Dispersive X-ray Reflectometry (EDXR) and Atomic Force Microscopy (AFM). The macromolecules were alternatively deposited over a self-assembled monolayer (SAM) of N-hydro... | ['Acetylcholinesterase', 'Antibodies, Immobilized', 'Antigen-Antibody Reactions', 'Enzymes, Immobilized', 'Gold', 'Membranes, Artificial', 'Microscopy, Atomic Force', 'Nanoparticles', 'Surface Properties'] | 19,899,801 | [['D08.811.277.352.100.170.176'], ['D12.776.124.486.485.114.207', 'D12.776.124.790.651.114.207', 'D12.776.377.715.548.114.207', 'D12.776.463.250'], ['G12.122'], ['D08.811.180', 'D12.776.463.500'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['E01.370.350... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Computational fluid dynamics modeling of symptomatic intracranial atherosclerosis may predict risk of stroke recurrence. | BACKGROUND: Patients with symptomatic intracranial atherosclerosis (ICAS) of ? 70% luminal stenosis are at high risk of stroke recurrence. We aimed to evaluate the relationships between hemodynamics of ICAS revealed by computational fluid dynamics (CFD) models and risk of stroke recurrence in this patient subset.METHOD... | ['Aged', 'Computer Simulation', 'Female', 'Hemodynamics', 'Humans', 'Hydrodynamics', 'Intracranial Arteriosclerosis', 'Male', 'Middle Aged', 'Models, Biological', 'Recurrence', 'Retrospective Studies', 'Risk Assessment', 'Stroke'] | 24,818,753 | [['M01.060.116.100'], ['L01.224.160'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.342'], ['C10.228.140.300.510.800', 'C14.907.137.126.372', 'C14.907.253.560.350'], ['M01.060.116.630'], ['E05.599.395'], ['C23.550.291.937'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.... | ['Named Groups [M]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Studies on the stability of preservatives under subcritical water conditions. | OBJECTIVE: The goal of this work was to further validate the subcritical water chromatography (SBWC) methods for separation and analysis of preservatives through the evaluation of analyte stability in subcritical water.METHODS: In this study, the degradation of preservatives was investigated at temperatures of 100-200°... | ['Chromatography, High Pressure Liquid', 'Cosmetics', 'Gas Chromatography-Mass Spectrometry', 'Preservatives, Pharmaceutical', 'Water'] | 25,565,502 | [['E05.196.181.400.300'], ['D27.720.269', 'J01.516.213'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D26.650.702', 'D27.720.744.771'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
An RFLP adjacent to the maize waxy gene has the structure of a transposable element. | Two maize inbred lines harbor non-mutant waxy (Wx) genes that display restriction fragment length polymorphism (RFLP) upstream from the start of Wx transcription. Sequencing of this region in the two strains revealed a DNA insertion with the structural features of a transposable element. The insertion is 316 bp in leng... | ['Base Sequence', 'DNA Restriction Enzymes', 'DNA Transposable Elements', 'Genes', 'Molecular Sequence Data', 'Plants', 'Polymorphism, Genetic', 'Polymorphism, Restriction Fragment Length', 'Zea mays'] | 2,895,417 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['G05.360.340.024.340'], ['L01.453.245.667'], ['B01.650'], ['G05.365.79... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Connexin 43 expression in intraperitoneal free gastric cancer cells in patients with gastric cancer]. | OBJECTIVE: To examine the association of connexin 43 (Cx43) in the intraperitoneal free gastric cancer cells and clinicopathological characteristics.METHODS: Immunohistochemistry and immunofluorescence staining were used to detect connexin 43 in 75 paraffin-embedded gastric cancer tissues, matched paracancerous tissue,... | ['Adult', 'Aged', 'Case-Control Studies', 'Connexin 43', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Metastasis', 'Neoplasm Staging', 'Peritoneal Neoplasms', 'Stomach Neoplasms', 'Young Adult'] | 20,878,577 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D12.776.543.585.250.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.650', 'C23.550.727.650'], ['E01.789.625'], ['C04.588.033.513', 'C04.588.274.780', 'C06.301.78... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Binding mode analyses of NAP derivatives as mu opioid receptor selective ligands through docking studies and molecular dynamics simulation. | Mu opioid receptor selective antagonists are highly desirable because of their utility as pharmacological probes for receptor characterization and functional studies. Furthermore, the mu opioid receptors act as an important target in drug abuse and addiction treatment. Previously, we reported NAP as a novel lead compou... | ['Hydrophobic and Hydrophilic Interactions', 'Ligands', 'Molecular Docking Simulation', 'Molecular Dynamics Simulation', 'Receptors, Opioid, mu', 'Static Electricity'] | 28,302,509 | [['G02.409'], ['D27.720.470.480'], ['E05.599.595.249', 'L01.224.160.249'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D12.776.543.750.695.620.550', 'D12.776.543.750.720.600.610.550', 'D12.776.543.750.750.555.610.550'], ['G01.358.500.249.820']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Acetabular re-revision with impaction bone grafting and a cemented polyethylene cup; a biological option for successive reconstructions. | INTRODUCTION: For the revision of failed acetabular components impaction bone grafting (IBG) with a cemented cup is a well known technique. Claims have been made that this is a biological reconstruction technique, restoring the bone stock loss and thereby facilitating future revisions. However, there are no scientific ... | ['Acetabulum', 'Adult', 'Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Hip', 'Bone Cements', 'Bone Transplantation', 'Female', 'Follow-Up Studies', 'Forecasting', 'Humans', 'Male', 'Middle Aged', 'Polyethylene', 'Postoperative Complications', 'Prosthesis Design', 'Prosthesis Failure', 'Reconstructive Surgical... | 25,362,880 | [['A02.835.232.043.825.108'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['D05.750.716.822.300', 'D25.720.716.822.300', 'D27.720.102.158', 'J01.637.051.720.716.822.300'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['E... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
[The effect of ionizing radiation on the transmethylation of phospholipids in the high molecular complex acyl-tRNA-synthetase]. | Transmethylation was found to contribute to the postirradiation redistribution of phospholipids which enter high molecular weight complexes of rat liver aminoacyl-tRNA-synthetases. The kinetic capacity of methyltransferases of codosome phospholipids was studied in normal conditions and at early times after irradiation ... | ['Amino Acyl-tRNA Synthetases', 'Animals', 'Liver', 'Methylation', 'Methyltransferases', 'Phosphatidylethanolamine N-Methyltransferase', 'Phospholipids', 'Rats'] | 2,928,482 | [['D08.811.464.263.200'], ['B01.050'], ['A03.620'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['D08.811.913.555.500'], ['D08.811.913.555.500.712'], ['D10.570.755'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prognostic value of serum resistin levels in patients with acute myocardial infarction. | BACKGROUND: Resistin is a novel adipokine that is suggested to be involved in inflammatory conditions and atherosclerosis.AIM: To investigate the prognostic importance of resistin in acute myocardial infarction (AMI) patients.METHODS: Resistin levels were measured in a population of 132 patients with AMI, of whom 72 (5... | ['Adult', 'Age Factors', 'Aged', 'Biomarkers', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Prognosis', 'Resistin', 'Risk Factors', 'Sex Factors'] | 23,633,273 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['D23.101'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['E01.789'], ['D06.472.699.042.750', 'D12.644.276.024.750', 'D12.644.548... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The depth to the epidural space. | Two hundred and ten patients, 145 males and 65 females, aged 20 to 72 years old, ready to receive extracorporeal shock wave lithotripsy under epidural anesthesia were studied to evaluate if any correlation existed between body weight, body surface area, body mass index and body height and the depth to the epidural spac... | ['Adult', 'Aged', 'Body Height', 'Body Mass Index', 'Body Surface Area', 'Body Weight', 'Epidural Space', 'Female', 'Humans', 'Male', 'Middle Aged', 'Reference Values', 'Spinal Canal'] | 2,633,021 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E01.370.600.115.100.231', 'E05.041.124.231', 'G07.100.100.231'], ['C23.888.144', 'E... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Mexican older adults with a wide socioeconomic perspective: health and aging]. | OBJECTIVES: Describe the Estudio Nacional de Salud y Envejecimiento en M?xico (ENASEM), also known by its name in English as the Mexican Health and Aging Study (MHAS).MATERIALS AND METHODS: This article summarizes the study design, its fieldwork protocol, survey contents, scope and analytical potential. It also present... | ['Aged', 'Aging', 'Health Status', 'Health Surveys', 'Humans', 'Interviews as Topic', 'Life Style', 'Longitudinal Studies', 'Mexico', 'Middle Aged', 'Prospective Studies', 'Rural Population', 'Socioeconomic Factors', 'Urban Population'] | 17,724,516 | [['M01.060.116.100'], ['G07.345.124'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['F01.829.45... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Effect of steroids for nasal polyposis surgery: A placebo-controlled, randomized, double-blind study. | OBJECTIVES/HYPOTHESIS: Although medical intervention is the first option for treatment of nasal polyps, surgery is still a therapeutic option for symptomatic cases that do not respond or partially respond to medical intervention. However, there is a need for high-level evidence for the preoperative use of steroids in n... | ['Administration, Intranasal', 'Adult', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Endoscopy', 'Female', 'Follow-Up Studies', 'Glucocorticoids', 'Humans', 'Male', 'Middle Aged', 'Nasal Obstruction', 'Nasal Polyps', 'Nasal Surgical Procedures', 'Prednisolone', 'Preoperative Care', 'Prospective Studies',... | 25,945,691 | [['E02.319.267.120.655.500'], ['M01.060.116'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E01.370.388.250', 'E04.502.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D06.472.040.543', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Study on the cyanobacterial toxin metabolism of Microcystis aeruginosa in nitrogen-starved conditions by a stable isotope labelling method. | In this study, the biosynthesis of microcystins (MCs) was investigated after long-term nitrogen-starved conditions in cyanobacterium Microcystis aeruginosa. The results demonstrated that the algal cells were able to survive in a non-growing state with nitrogen starvation for more than one month. The physiological prope... | ['Isotope Labeling', 'Microcystins', 'Microcystis', 'Nitrogen', 'Peptides, Cyclic'] | 30,952,000 | [['E05.522'], ['D04.345.566.447', 'D12.644.641.447', 'D23.946.123.574'], ['B03.280.500', 'B03.440.475.100.500'], ['D01.268.604', 'D01.362.625'], ['D04.345.566', 'D12.644.641']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of short-lived electrophilic metabolites of the anticancer agent laromustine (VNP40101M). | Laromustine (VNP40101M; 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-(methylamino) carbonylhydrazine) is a novel sulfonylhydrazine alkylating agent. Phase 1 metabolism of laromustine was reported recently and showed that laromustine undergoes rearrangement, dehalogenation, and hydrolysis at physiological pH to form acti... | ['Acetylcysteine', 'Antineoplastic Agents', 'Carbon Isotopes', 'Chromatography, High Pressure Liquid', 'Cysteine', 'Glutathione', 'Humans', 'Hydrazines', 'Magnetic Resonance Spectroscopy', 'Microsomes, Liver', 'NADP', 'Neoplasms', 'Spectrometry, Mass, Electrospray Ionization', 'Sulfonamides'] | 21,361,357 | [['D02.886.030.230.259', 'D12.125.166.230.259'], ['D27.505.954.248'], ['D01.268.150.075', 'D01.496.123'], ['E05.196.181.400.300'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D12.644.456.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.442'], ['E05.196.867.519'], ['A11.2... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of hypovolemic hypotensive shock on somatosensory and motor evoked potentials. | The utility of evoked potentials in monitoring spinal cord and cerebral function in various neurosurgical and orthopedic operations has now been established. To study the effects of graded hypotension upon spinal and cortical somatosensory evoked potentials (SMEPs), and spinal motor evoked potentials (SMEPs), 12 anesth... | ['Animals', 'Cats', 'Evoked Potentials', 'Evoked Potentials, Somatosensory', 'Female', 'Homeostasis', 'Hypotension, Controlled', 'Male', 'Motor Cortex', 'Shock', 'Spinal Cord', 'Time Factors'] | 2,918,975 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['G07.265.216.500', 'G11.561.200.500'], ['G07.265.216.500.400', 'G11.561.200.500.400'], ['G07.410'], ['E03.545'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['C23.550.835'], ['A08.186.854'], ['G01.910.857']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Persulfonylation of amines applied to the synthesis of higher generation dendrimers. | Systematic analysis of the persulfonylation of branched aromatic oligoamines with different arylsulfonyl chlorides allowed optimization of the repetitive steps involved in the synthesis of the sulfonimide-based dendrimers. The optimized procedures afforded the fourth generation N- and pentaphenylene-centered dendrimers... | ['Amines', 'Dendrimers', 'Molecular Structure', 'Sulfur Compounds'] | 18,358,000 | [['D02.092'], ['D05.750.327', 'E02.319.300.380.200', 'J01.637.512.600.200'], ['G02.111.570', 'G02.466'], ['D01.875', 'D02.886']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Increased expression of the monocyte differentiation antigen CD14 in extrinsic allergic alveolitis. | Expression of the CD14 antigen was studied on alveolar macrophages in extrinsic allergic alveolitis (EAA), using immunocytochemistry and cytometry. Compared to control donors, EAA patients had higher percentages of My4 positive cells (40 versus 22%), and the antigen density was fourfold higher (410 versus 92 channels).... | ['Adult', 'Aged', 'Alveolitis, Extrinsic Allergic', 'Antigens, CD', 'Antigens, Differentiation, Myelomonocytic', 'Female', 'Humans', 'Lipopolysaccharide Receptors', 'Macrophages, Alveolar', 'Male', 'Middle Aged', 'Monocytes'] | 7,510,201 | [['M01.060.116'], ['M01.060.116.100'], ['C08.381.483.125', 'C08.674.055', 'C20.543.480.680.075'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.900', 'D23.101.100.900'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.395.550.448.100', 'D12.776.543.484.500.100', 'D12.776.543.550.418.100', 'D1... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reality of obesity paradox: Results of percutaneous coronary intervention in Middle Eastern patients. | Objective The aim of this study was to assess the baseline clinical characteristics, coronary angiographic features, and adverse cardiovascular events during hospitalization and at 1 year of follow-up in obese patients compared with overweight and normal/underweight patients. Methods A prospective, multicenter study of... | ['Body Mass Index', 'Coronary Angiography', 'Coronary Artery Disease', 'Hospitalization', 'Humans', 'Middle East', 'Obesity', 'Percutaneous Coronary Intervention'] | 29,468,911 | [['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.64... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[Surgical strategy for juxtapapillary ulcers of the duodenum]. | Results of surgical treatment of 89 patients with ulcer of the duodenum with postbulbar localization were studied. A classification of postbulbar ulcers was proposed taking into consideration the degree of involvement of bile-excreting pathways and major duodenal papilla into the periulcerous process. In extrapapillary... | ['Adult', 'Ampulla of Vater', 'Anastomosis, Surgical', 'Duodenal Ulcer', 'Humans', 'Practice Guidelines as Topic', 'Stomach'] | 21,506,351 | [['M01.060.116'], ['A03.159.183.079.300.950', 'A03.556.124.684.124.236', 'A03.556.875.249.160', 'A03.734.667.500'], ['E04.035'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.350.650', 'N05.700.350.650'], ['A03.556.875.875']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Multiplex RT-PCR for the detection of common BCR-ABL fusion transcripts in paraffin-embedded tissues from patients with chronic myeloid leukemia and acute lymphoblastic leukemia. | Diagnosis of chronic myeloid leukemia and acute lymphoblastic leukemia requires the investigation of the Philadelphia chromosome translocation t(9;22) or the molecular detection of BCR-ABL fusion transcripts. Determination of the type of fusion transcript is crucial for quantitative molecular monitoring the course of t... | ['Bone Marrow Cells', 'Cell Line, Tumor', 'DNA Primers', 'DNA, Neoplasm', 'Fusion Proteins, bcr-abl', 'Humans', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Paraffin Embedding', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'RNA, Neoplasm', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sensitivity and... | 12,960,692 | [['A11.148', 'A15.378.316'], ['A11.251.210.190', 'A11.251.860.180'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.425'], ['D08.811.913.696.620.682.725.500.500', 'D12.776.602.500.500.100', 'D12.776.624.664.500.100', 'D12.776.624.664.700.171.500'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Bias in treatment trials. | Rigorous treatment trials exhibit a number of key features to guard against bias. Randomization, blinding (of patients, care staff and assessors), full follow-up on all patients, and 'intention-to-treat' analyses all contribute to removing bias so that any true treatment effect can be revealed. This article outlines th... | ['Bias', 'Clinical Trials as Topic', 'Double-Blind Method', 'Follow-Up Studies', 'Humans', 'Patient Selection', 'Random Allocation', 'Single-Blind Method', 'Therapeutic Equivalency', 'Treatment Outcome'] | 10,621,819 | [['N05.715.350.150', 'N06.850.490.500'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.3... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Wegener's granulomatosis: role of environmental exposures. | OBJECTIVE: The etiology of Wegener's granulomatosis (WG) remains unknown. The predominant involvement of the airways and the presence of neutrophilic alveolitis at disease onset have led us to postulate that an inhaled agent may trigger the onset of WG. This study is designed to analyze differences in self-reported env... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Air Pollutants', 'Case-Control Studies', 'Child', 'Disease Susceptibility', 'Female', 'Granulomatosis with Polyangiitis', 'Humans', 'Inhalation Exposure', 'Male', 'Maryland', 'Middle Aged', 'Ohio', 'Pulmonary Fibrosis', 'Rheumatic Diseases', 'Sarcoidosis, Pulmonary'... | 9,844,758 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.888.284.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['C23.550.291.687', 'G07.100.250'], ['C08.381.483.950', 'C14.907.940.897.249.750', 'C20.111.193.875'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Is the risk of bipolar disorder in twins equal to the risk in singletons? A nationwide register-based study. | BACKGROUND: A previous study demonstrated a higher rate of schizophrenia in dizygotic twins than in the general population, and a higher rate of schizophrenia in siblings of dizygotic twins than in siblings of monozygotic twins and singletons, pointing to a common genetic predisposition for dizygotic twinning and schiz... | ['Adult', 'Aged', 'Bipolar Disorder', 'Cohort Studies', 'Denmark', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Male', 'Middle Aged', 'Registries', 'Risk Factors', 'Siblings', 'Twins, Dizygotic', 'Twins, Monozygotic'] | 15,306,139 | [['M01.060.116'], ['M01.060.116.100'], ['F03.084.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['Z01.542.816.124'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.30... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Fluoroquinolone antibiotics determination in piggeries environmental waters. | To trace the contamination and evaluate the environmental impact of piggeries, the occurrence of norfloxacin (NOR), ciprofloxacin (CIPRO), enrofloxacin (ENRO) and sarafloxacin (SARA) residues were evaluated in water for swine consumption, piggeries' wastewaters, drainage waters and a river receiving piggery effluents. ... | ['Animal Husbandry', 'Animals', 'Animals, Domestic', 'Anti-Bacterial Agents', 'Environmental Monitoring', 'Fluoroquinolones', 'Limit of Detection', 'Rivers', 'Swine', 'Waste Disposal, Fluid', 'Water', 'Water Pollutants, Chemical'] | 20,445,852 | [['J01.040.090'], ['B01.050'], ['B01.050.050.116'], ['D27.505.954.122.085'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D03.633.100.810.835.322'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['B01.050.150.900.649.313.500.88... | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Accurate placement of central venous catheter--ECG-guided method vs patient height method]. | Correct positioning of central venous catheters (CVC) is important. We compared the positioning of CVCs by ECG-monitoring via the guidewire and that by method using patient height. "Certofix" triple-lumen CVCs were inserted in 60 cardiac surgical patients via right internal jugular puncture. Of these, 30 were placed wi... | ['Aged', 'Body Height', 'Catheterization, Central Venous', 'Electrocardiography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Monitoring, Physiologic'] | 11,840,660 | [['M01.060.116.100'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.37... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genetic diversity among clonal lineages within Escherichia coli O157:H7 stepwise evolutionary model. | Escherichia coli O157:H7 variants were examined for trait mutations and by molecular subtyping to better define clonal complexes postulated on the O157:H7 evolution model. Strains of beta-glucuronidase-positive, sorbitol-negative O157:H7 isolated in United States and Japan were identical to A5 clonal strain and shared ... | ['Electrophoresis, Gel, Pulsed-Field', 'Escherichia coli Infections', 'Escherichia coli O157', 'Evolution, Molecular', 'Genetic Variation', 'Humans'] | 18,217,554 | [['E05.196.401.220', 'E05.301.300.220'], ['C01.150.252.400.310.330'], ['B03.440.450.425.325.300.800.250.500', 'B03.660.250.150.180.100.800.250.500'], ['G05.045.250', 'G16.075.250'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The noise-resilient brain: Resting-state oscillatory activity predicts words-in-noise recognition. | The role of neuronal oscillations in the processing of speech has recently come to prominence. Since resting-state (RS) brain activity has been shown to predict both task-related brain activation and behavioural performance, we set out to establish whether inter-individual differences in spectrally-resolved RS-MEG powe... | ['Acoustic Stimulation', 'Adult', 'Brain', 'Brain Mapping', 'Female', 'Forecasting', 'Humans', 'Magnetoencephalography', 'Male', 'Noise', 'Recognition, Psychology', 'Rest', 'Speech', 'Speech Perception', 'Young Adult'] | 31,918,321 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.116'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.376.500', 'E01.370.405.440', 'E05.540.500'], ['G01.750.770.776.567', 'G16.500.275.600', 'N0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Adenoma with multiple hyperplastic nodules in noncirrhotic liver possibly related to long-term administration of a hypolipidemic drug. | Described here is an autopsy case of a 76-year-old woman with preneoplastic and other adenomatous hepatocellular lesions. Multiple small hyperplastic liver foci with PAS positive reaction and adenomatous nodular lesions were noted in a non-cirrhotic liver. These lesions resembled altered foci or neoplastic nodules whic... | ['Aged', 'Carcinoma, Hepatocellular', 'Clofibrate', 'Female', 'Humans', 'Hypercholesterolemia', 'Hyperplasia', 'Hypertension', 'Liver', 'Liver Neoplasms', 'Precancerous Conditions'] | 6,287,798 | [['M01.060.116.100'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['D02.241.081.114.968.500.500.195', 'D02.355.726.305.500.195', 'D02.455.426.559.389.657.654.305.500.195'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.584.500.500.396'], ['C23.550.444'], ['C14.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mobile application for the evaluation and planning of nursing workload in the intensive care unit. | OBJECTIVE: In this study, we present an application type software which employs the Nursing Activities Score (NAS), a management tool for measuring nursing workload prospectively.METHOD: The system was developed in two modules: WEB (controlled from an Internet browser) for data administration using Java Script; and APP... | ['Data Management', 'Humans', 'Intensive Care Units', 'Internet', 'Mobile Applications', 'Prospective Studies', 'Smartphone', 'Workload'] | 32,179,255 | [['L01.399.375', 'L01.453.233', 'L01.470.563'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['L01.224.230.110.500'], ['L01.224.900.685'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['L01.178.847.698.300.250', 'L01.224.230.260.550.500.750'], ['I03... | ['Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Molecular characterization and inhibition analysis of the acetylcholinesterase gene from the silkworm maggot, Exorista sorbillans. | Several organophosphorus (OP) insecticides can selectively kill the silkworm maggot, Exorista sorbillans (Es) (Diptera: Tachinidae), while not obviously affecting the host (Bombyx mori) larvae, but the mechanism is not yet clear. In this study, the cDNA encoding an acetylcholinesterase (AChE) from the field Es was isol... | ['Acetylcholinesterase', 'Amino Acid Sequence', 'Amino Acid Substitution', 'Animals', 'Bombyx', 'Cholinesterase Inhibitors', 'Diptera', 'Insecticides', 'Molecular Sequence Data', 'Point Mutation', 'Recombinant Proteins', 'Sequence Alignment'] | 20,797,321 | [['D08.811.277.352.100.170.176'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['B01.050.500.131.617.720.500.500.937.650.100'], ['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['B01.050.500.131.617.720.500.500.750'], ['D27.720.031.700.49... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Transutricular seminal vesiculoscopy in the management of symptomatic midline cyst of the prostate. | PURPOSE: To evaluate the utility of transutricular seminal vesiculoscopy as a diagnostic and therapeutic option for symptomatic midline cyst of the prostate in patients with hematospermia and symptoms associated with prostatitis.MATERIALS AND METHODS: From January 2005 to July 2013, 61 patients with symptomatic (hemato... | ['Adult', 'Aged', 'Cysts', 'Endoscopy', 'Humans', 'Male', 'Middle Aged', 'Prostatic Diseases', 'Retrospective Studies', 'Seminal Vesicles', 'Urologic Surgical Procedures, Male'] | 26,387,919 | [['M01.060.116'], ['M01.060.116.100'], ['C04.182', 'C23.300.306'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C12.294.565'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Does a "one-stop" gynecology screening clinic for women in hereditary nonpolyposis colorectal cancer families have an impact on their psychological morbidity and perception of health? | Screening programs can reduce the burden of disease, however, they can be associated with raised levels of anxiety. The risk of endometrial and ovarian cancer is increased in hereditary nonpolyposis colorectal cancer (HNPCC). There is no prospective evidence to support screening for gynecological disease in HNPCC, howe... | ['Adult', 'Anxiety', 'Attitude to Health', 'Colorectal Neoplasms, Hereditary Nonpolyposis', 'Depression', 'Female', 'Genital Neoplasms, Female', 'Humans', 'Mass Screening', 'Perception'] | 17,587,321 | [['M01.060.116'], ['F01.470.132'], ['F01.100.150', 'N05.300.150'], ['C04.588.274.476.411.307.190', 'C04.700.250', 'C06.301.371.411.307.190', 'C06.405.249.411.307.190', 'C06.405.469.158.356.190', 'C06.405.469.491.307.190', 'C16.320.700.250', 'C18.452.284.255'], ['F01.145.126.350'], ['C04.588.945.418', 'C13.351.937.418']... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Pulmonary carcinoid tumors--ten years experience]. | Pulmonary carcinoid tumors are rare, accounting for as many as 2% of all pulmonary neoplasms and for 10% of carcinoid tumors overall. Previously classified as bronchial adenomas, actually are classified as neuroendocrine tumors. They have a subclassification into typical classed as low-grade malignant neoplasm and atyp... | ['Adolescent', 'Adult', 'Carcinoid Tumor', 'Child', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Retrospective Studies'] | 15,895,123 | [['M01.060.057'], ['M01.060.116'], ['C04.557.465.625.650.200', 'C04.557.470.200.025.200', 'C04.557.580.625.650.200'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Becoming a community matron: the transition from acute to primary care. | Community matrons are an important part of the policy of community-based management of long-term conditions. In contrast to some early conceptions of the role, community matrons can come from all areas of nursing. This article draws together two personal accounts by nurses from one primary care trust who have made the ... | ['Career Mobility', 'Case Management', 'Clinical Competence', 'Community Health Nursing', 'England', 'Humans', 'Nurse Administrators', 'Personnel Selection', 'Primary Nursing', 'Staff Development', 'Task Performance and Analysis'] | 17,044,246 | [['N01.824.245.175', 'N01.824.547.330'], ['N04.590.233.624.250'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['H02.478.676.150', 'N02.421.143.150'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.070.670', 'M01.526.485.650.580', 'N02.360.650.580'], ['N04.452.677.500'], ['N02.421... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Staphylococcus aureus â-toxin production is common in strains with the â-toxin gene inactivated by bacteriophage. | BACKGROUND: Staphylococcus aureus causes life-threatening infections, including infective endocarditis, sepsis, and pneumonia. â-toxin is a sphingomyelinase encoded for by virtually all S. aureus strains and exhibits human immune cell cytotoxicity. The toxin enhances S. aureus phenol-soluble modulin activity, and its a... | ['Animals', 'Bacterial Toxins', 'Disease Models, Animal', 'Endocarditis, Bacterial', 'Gene Silencing', 'Hemolysin Proteins', 'Mutagenesis, Insertional', 'Pneumonia, Staphylococcal', 'Prophages', 'Rabbits', 'Recombination, Genetic', 'Sepsis', 'Sphingomyelin Phosphodiesterase', 'Staphylococcus Phages', 'Staphylococcus au... | 24,620,023 | [['B01.050'], ['D23.946.123'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C01.150.252.245', 'C01.190.249', 'C14.260.249', 'C14.280.282.407'], ['G05.308.203.374'], ['D12.776.543.695.444'], ['E05.393.420.601.550', 'G05.365.590.575', 'G05.558.550'], ['C01.150.252.410.868.675', 'C01.150.252.620.620', 'C01.748.610.540... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Delay in seeking care for tuberculosis symptoms among adults newly diagnosed with HIV in rural Malawi. | SETTING: Ten primary health clinics in rural Thyolo District, Malawi.OBJECTIVE: Tuberculosis (TB) is a common initial presentation of human immunodeficiency virus (HIV) infection. We investigated the time from TB symptom onset to HIV diagnosis to describe TB health-seeking behaviour in adults newly diagnosed with HIV.D... | ['Adult', 'Coinfection', 'Cross-Sectional Studies', 'Delayed Diagnosis', 'Female', 'HIV Infections', 'Humans', 'Logistic Models', 'Malawi', 'Male', 'Multivariate Analysis', 'Patient Acceptance of Health Care', 'Poverty', 'Rural Population', 'Time Factors', 'Tuberculosis'] | 29,471,905 | [['M01.060.116'], ['C01.218'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.110', 'E02.760.273', 'N02.421.585.273'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.4... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Protochlamydia naegleriophila as etiologic agent of pneumonia. | Using ameba coculture, we grew a Naegleria endosymbiont. Phenotypic, genetic, and phylogenetic analyses supported its affiliation as Protochlamydia naegleriophila sp. nov. We then developed a specific diagnostic PCR for Protochlamydia spp. When applied to bronchoalveolar lavages, results of this PCR were positive for 1... | ['Acanthamoeba castellanii', 'Animals', 'Bronchoalveolar Lavage Fluid', 'Chlamydia Infections', 'Chlamydiales', 'DNA, Bacterial', 'Humans', 'Naegleria', 'Pneumonia, Bacterial', 'Polymerase Chain Reaction'] | 18,258,101 | [['B01.046.500.100.075.080.150'], ['B01.050'], ['E05.927.100.500'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C12.294.668.281.301', 'C13.351.500.711.281.301'], ['B03.440.190'], ['D13.444.308.212'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.046.500.700.710... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Myosin isoform expression in the prehensile tails of didelphid marsupials: functional differences between arboreal and terrestrial opossums. | Prehensile tails are defined as having the ability to grasp objects and are commonly used as a fifth appendage during arboreal locomotion. Despite the independent evolution of tail prehensility in numerous mammalian genera, data relating muscle structure, physiology, and function of prehensile tails are largely incompl... | ['Animals', 'Blotting, Western', 'Electrophoresis, Polyacrylamide Gel', 'Immunoenzyme Techniques', 'Locomotion', 'Muscle Fibers, Skeletal', 'Myosin Heavy Chains', 'Opossums', 'Protein Isoforms'] | 24,832,677 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.196.401.402', 'E05.301.300.319'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['G07.568.500', 'G11.427.410.568'], ['A10.690.552.500.500', 'A11.620.249'], ['D05.750.078.730.475.100', 'D... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pectenotoxin-2 synthetic studies. 1. Alkoxide precoordination to [Rh(NBD)(DIPHOS-4)]BF(4) allows directed hydrogenation of a 2,3-dihydrofuran-3-ol without competing furan production. | [reaction: see text] The alkoxide-directed hydrogenation shown is reported as a key step in a concise synthesis of a fully functionalized precursor to the C29-C40 F/G sector of pectenotoxin-2. | ['Antineoplastic Agents', 'Furans', 'Hydrogen', 'Macrolides', 'Magnetic Resonance Spectroscopy', 'Oxides', 'Pyrans'] | 11,893,190 | [['D27.505.954.248'], ['D03.383.312'], ['D01.268.406', 'D01.362.340'], ['D02.540.505', 'D02.540.576.500', 'D04.345.674.500'], ['E05.196.867.519'], ['D01.248.497.158.685', 'D01.650.550'], ['D03.383.663']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The prospects of a subnanometer focused neon ion beam. | The success of the helium ion microscope has encouraged extensions of this technology to produce beams of other ion species. A review of the various candidate ion beams and their technical prospects suggest that a neon beam might be the most readily achieved. Such a neon beam would provide a sputtering yield that excee... | ['Ions', 'Microscopy', 'Neon', 'Research'] | 21,796,647 | [['D01.248.497'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['D01.268.613.600', 'D01.362.641.592'], ['H01.770.644']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[The immunosuppressive activity of Shigella sonnei differing by the presence of plasmid pSS120]. | S. sonnei virulent strain containing invasiveness plasmid pSS120 was found to suppress delayed hypersensitivity (DH) to nonbacterial antigens. In the filtrate of the culture of this strain extracellular lipopolysaccharide (LPS), capable of inducing immunosuppressing activity in nonvirulent bacteria, was detected. S. so... | ['Animals', 'DNA Transposable Elements', 'Escherichia coli', 'Hypersensitivity, Delayed', 'Immune Tolerance', 'Immunization', 'Lipopolysaccharides', 'Mice', 'Mice, Inbred BALB C', 'Plasmids', 'Shigella sonnei', 'Virulence'] | 9,460,870 | [['B01.050'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C20.543.418'], ['G12.535.425'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of body mass index on recurrences in tamoxifen and anastrozole treated women: an exploratory analysis from the ATAC trial. | PURPOSE: Third-generation aromatase inhibitors have been widely used in postmenopausal women for the adjuvant treatment of hormone receptor-positive breast cancer. As aromatase inhibitors work by inhibiting the conversion of androgens to estrogens in adipose tissue, we hypothesized that anastrozole may be more effectiv... | ['Adult', 'Aged', 'Anastrozole', 'Antineoplastic Agents, Hormonal', 'Aromatase Inhibitors', 'Body Mass Index', 'Breast Neoplasms', 'Double-Blind Method', 'Estrogen Antagonists', 'Female', 'Humans', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Nitriles', 'Tamoxifen', 'Triazoles'] | 20,547,990 | [['M01.060.116'], ['M01.060.116.100'], ['D02.626.218', 'D03.383.129.799.275'], ['D27.505.954.248.169'], ['D27.505.519.389.870.300', 'D27.505.696.399.450.327.149', 'D27.505.696.399.450.855.300'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C04.588.180', 'C17.800.090.50... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Primary cilia are not calcium-responsive mechanosensors. | Primary cilia are solitary, generally non-motile, hair-like protrusions that extend from the surface of cells between cell divisions. Their antenna-like structure leads naturally to the assumption that they sense the surrounding environment, the most common hypothesis being sensation of mechanical force through calcium... | ['Animals', 'Calcium', 'Calcium Signaling', 'Cilia', 'Embryo, Mammalian', 'Epithelial Cells', 'Female', 'Hair Cells, Auditory, Inner', 'Kidney', 'Male', 'Mechanotransduction, Cellular', 'Mice', 'Mice, Transgenic', 'Models, Biological'] | 27,007,841 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['A11.284.180.165'], ['A16.254'], ['A11.436'], ['A08.675.650.250.250', 'A08.675.650.915.750.600.350.350', 'A08.800.950.750.600.350.350', 'A09.246.300.246.577.325.315', 'A11.671.650.250.250... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antifungal activities and chemical composition of some medicinal plants. | The use of and search for drugs and dietary supplements derived from plants have accelerated in recent years. Ethnopharmacologists, botanists, microbiologists and natural-products scientists are combing the earth for phytochemicals and leads, which could be developed for treatment of infectious diseases. The aim of thi... | ['Antifungal Agents', 'Aspergillus flavus', 'Bupleurum', 'Fusarium', 'Humans', 'Microbial Sensitivity Tests', 'Oils, Volatile', 'Plant Oils', 'Plants, Medicinal', 'Stachys', 'Thymus Plant'] | 24,768,063 | [['D27.505.954.122.136'], ['B01.300.381.081.170'], ['B01.650.940.800.575.912.250.075.144'], ['B01.300.381.366'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D10.627.675'], ['D10.627.700', 'D20.215.784.750'], ['B01.650.560'], ['B01.650.940.800.575.912... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Major histocompatibility class I presentation of soluble antigen facilitated by Mycobacterium tuberculosis infection. | Cell-mediated immune responses are essential for protection against many intracellular pathogens. For Mycobacterium tuberculosis (MTB), protection requires the activity of T cells that recognize antigens presented in the context of both major histocompatibility complex (MHC) class II and I molecules. Since MHC class I ... | ['ATP-Binding Cassette Transporters', 'Animals', 'Antigen-Presenting Cells', 'Cell Line', 'Escherichia coli', 'Hematopoietic Stem Cells', 'Histocompatibility Antigens Class I', 'Histocompatibility Antigens Class II', 'Immunity, Cellular', 'Interleukin-2', 'Listeria monocytogenes', 'Macrophages', 'Mice', 'Mice, Inbred C... | 8,876,215 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['B01.050'], ['A11.066', 'A15.382.066'], ['A11.251.210'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['D12.776.395.550.489', 'D12.776.543.550.439', 'D23.050.301.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Aiming at low disease activity in rheumatoid arthritis with initial combination therapy or initial monotherapy strategies: the BeSt study. | AIM: To evaluate the efficacy and safety of four different treatment strategies for patients with early rheumatoid arthritis (RA).METHODS: In the BeSt study, 508 patients with newly diagnosed (< 2 years) active RA were randomised to be treated according to four treatment strategies: 1. sequential monotherapy, 2. step u... | ['Adult', 'Aged', 'Antibodies, Monoclonal', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'Drug Administration Schedule', 'Drug Therapy, Combination', 'Female', 'Humans', 'Infliximab', 'Male', 'Methotrexate', 'Middle Aged', 'Prednisone', 'Remission Induction', 'Severity of Illness Index', 'Sulfasalazine', 'Treatment... | 17,083,767 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E02.319.283'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.12... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hydrogen-bonded complexes of the ribodinucleoside monophosphates in aqueous solution. Proton magnetic resonance studies. | A proton magnetic resonance study of the chemical shifts of a series of ribodinucleoside monophosphates in neutral H2O solution has been recorded in the 1-100 mM concentration range. The self-complementary dinucleoside monophosphates CpG and GpC and the complementary mixture GpU + ApC form intermolecular hydrogen-bonde... | ['Binding Sites', 'Hydrogen Bonding', 'Magnetic Resonance Spectroscopy', 'Nucleic Acid Conformation', 'Oligoribonucleotides', 'Temperature', 'Thermodynamics'] | 1,252,443 | [['G02.111.570.120'], ['G02.282'], ['E05.196.867.519'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.695.578.424.500'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['G01.906']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Heterotopic ossification in colorectal adenocarcinoma [corrected]. | Heterotopic ossification in Adenocarcinomas of the colon is uncommon. The clinical presentation of these patients is similar to those without osseous metaplasia. Its importance lies in the fact that it may be misdiagnosed for a carcinosarcoma. Which has a poorer prognosis. These two cases are reported because of its ra... | ['Adenocarcinoma', 'Aged', 'Female', 'Humans', 'Male', 'Middle Aged', 'Ossification, Heterotopic', 'Rectal Neoplasms'] | 8,300,182 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.751'], ['C04.588.274.476.411.307.790', 'C06.301.371.411.307.790', 'C06.405.249.411.307.790', 'C06.405.469.491.307.790', 'C06.405.469.860.180.500']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Strictureplasty. An alternative in the surgical treatment of Crohn's disease. | A patient with severe, multilevel, partial obstruction of the jejunum and ileum secondary to Crohn's disease successfully underwent strictureplasty of the stenotic areas as described. Intestinal length was fully preserved. Complete healing and patency without fistulization was observed on reexploration seven months lat... | ['Adult', 'Constriction, Pathologic', 'Crohn Disease', 'Humans', 'Intestinal Obstruction', 'Intestine, Small', 'Male', 'Radiography'] | 6,732,495 | [['M01.060.116'], ['C23.300.287'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531'], ['A03.556.124.684'], ['E01.370.350.700']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The unusual thermodynamic properties of compact forms pFh fragments (hinge region) IgG3 Kuc and Sur]. | pFh fragments from the hinge region of human IgG3 Kuc and Sur can fold into compact form, resulting the formation of proteins with secondary (super-secondary) structure, which is represented almost exclusively double poly-L-proline helix. It was demonstrated by several methods that the thermal denaturation of compact f... | ['Hot Temperature', 'Humans', 'Hydrogen-Ion Concentration', 'Immunoglobulin G', 'Peptide Fragments', 'Proline', 'Protein Denaturation', 'Protein Folding', 'Protein Stability', 'Protein Structure, Secondary', 'Thermodynamics'] | 22,295,577 | [['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['D12.644.541... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
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