Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Abnormal degree centrality in neurologically asymptomatic patients with end-stage renal disease: A resting-state fMRI study. | OBJECTIVE: End-stage renal disease (ESRD), characterized by multi-organ dysfunction, has been shown to co-occur with abnormal brain function. Previous resting-state fMRI studies suggested that regional brain spontaneous activity and functional connectivity within the default mode network are abnormal in ESRD patients. ... | ['Adolescent', 'Adult', 'Asymptomatic Diseases', 'Brain', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Nerve Net', 'Rest', 'Young Adult'] | 26,160,274 | [['M01.060.057'], ['M01.060.116'], ['C23.550.291.187'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['A08.511'], ['I03.450.769.647'], ['M01.060.116.815']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Neural correlates of ankle movements during different motor tasks: A feasibility study. | This ongoing study investigates the neural correlates of ankle dorsi-plantar flexion in active, passive, and proprioceptive tasks. Specifically, we investigated two proprioceptive matching tasks that required a simple combination of active and passive ankle movements: (1) a memory-based ipsilateral matching task and (2... | ['Adult', 'Ankle', 'Ankle Joint', 'Brain', 'Brain Mapping', 'Feasibility Studies', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Motor Cortex', 'Movement', 'Radiography', 'Young Adult'] | 26,737,338 | [['M01.060.116'], ['A01.378.610.050'], ['A02.835.583.378.062'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A08.18... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Lack of efficacy of moclobemide or imipramine in the treatment of recurrent brief depression: results from an exploratory randomized, double-blind, placebo-controlled treatment study. | 'Recurrent brief depression' (RBD) is a common, distressing and impairing depressive disorder for which there is no current proven pharmacological or psychological treatment. This multicentre, randomized, fixed-dose, parallel-group, placebo-controlled study of the reversible inhibitor of monoamine oxidase moclobemide (... | ['Adolescent', 'Adult', 'Antidepressive Agents', 'Depressive Disorder', 'Double-Blind Method', 'Female', 'Humans', 'Imipramine', 'Male', 'Middle Aged', 'Moclobemide', 'Recurrence', 'Young Adult'] | 24,859,491 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.427.700.122'], ['F03.600.300'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.300.240.485'], ['M01.060.116.630'], ['D02.065.277.600', 'D02.241.223.100.100.600', 'D02.241.22... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia. | Working memory (WM) impairment is a promising candidate endophenotype for schizophrenia that could facilitate the identification of susceptibility genes for this disorder. The validity of this putative endophenotype was assessed by determining whether 149 probands with schizophrenia and 337 of their first-degree relati... | ['Adult', 'Cognition Disorders', 'Female', 'Genetic Predisposition to Disease', 'Humans', 'Male', 'Memory, Short-Term', 'Middle Aged', 'Neuropsychological Tests', 'Phenotype', 'Psychometrics', 'Reference Values', 'Schizophrenia', 'Serial Learning', 'Verbal Learning'] | 18,406,578 | [['M01.060.116'], ['F03.615.250'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.407'], ['M01.060.116.630'], ['F04.711.513'], ['G05.695'], ['F04.711.780'], ['E05.978.810'], ['F03.700.750'], ['F02.463.425.952.747'], ['F02.463.425.952']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ceramide increase cytoplasmic Ca2+ concentration in Jurkat T cells by liberation of calcium from intracellular stores and activation of a store-operated calcium channel. | The effect of ceramide on the cytoplasmic Ca2+ concentration ([Ca2+]i) varies depending on the cell type. We have found that in Jurkat human T cells ceramide increases the [Ca2+]i from a thapsigargin-sensitive calcium pool and the subsequent activation of a capacitative Ca2+ entry. This effect occurs both in the presen... | ['Calcium', 'Calcium Channels', 'Cell Membrane', 'Ceramides', 'Cytoplasm', 'Humans', 'Hydrolysis', 'Inositol 1,4,5-Trisphosphate', 'Jurkat Cells', 'Lymphocytes', 'Magnesium', 'Manganese', 'Microscopy, Confocal', 'Patch-Clamp Techniques', 'Signal Transduction', 'Sphingolipids', 'Sphingosine', 'Thapsigargin', 'Time Facto... | 15,797,246 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['A11.284.149'], ['D02.065.313', 'D09.400.410.420.525.200', 'D10.390.470.675.200', 'D10.570.877.360.612.200'], ['A11.284.430.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Flow cytometric measurement of ploidy and proliferation in effusions of ovarian carcinoma and their possible prognostic significance. | The cellular DNA pattern of ascites and pleural effusions from 81 patients with advanced ovarian carcinoma was prospectively studied by means of flow cytometric DNA analysis. The degree of ploidy and the proportion of S-phase values were correlated to histological differentiation, to status, and to the development of d... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aging', 'Ascitic Fluid', 'Carcinoma', 'Cell Division', 'DNA', 'Female', 'Flow Cytometry', 'Humans', 'Interphase', 'Menopause', 'Middle Aged', 'Ovarian Neoplasms', 'Pleural Effusion', 'Ploidies', 'Prognosis'] | 2,807,018 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['A12.207.119'], ['C04.557.470.200'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D13.444.308'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', '... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Multiple phytoplasmas associated with potato diseases in Mexico. | In recent years, the potato crop in Mexico has been notably affected by diseases recognized as potato purple top (PPT) in foliage and potato hair sprouts (PHS) in germinating tubers. In both cases, these syndromes reduce production by affecting viability of the tubers used as seeds. There is evidence indicating that ph... | ['Acholeplasmataceae', 'Base Sequence', 'Mexico', 'Phylogeny', 'Plant Diseases', 'Plant Tubers', 'Polymorphism, Restriction Fragment Length', 'RNA, Ribosomal, 16S', 'Restriction Mapping', 'Solanum tuberosum'] | 12,619,818 | [['B03.440.860.074'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['Z01.107.567.589'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G15.610'], ['A18.400.625'], ['G05.365.795.595'], ['D13.444.735.686.670'], ['E05.393.183.620.650', 'E05.393.712'], ['B01.650.940.800.575.912.250.908.500.725.777']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Rapid improvement in post-infectious gastroparesis symptoms with mirtazapine. | We report the case of a 34-year-old woman with severe post-infectious gastroparesis who was transferred from an outside medical facility for a second opinion regarding management. This patient had no prior history of gastrointestinal symptoms. However, in the aftermath of a viral illness, she developed two months of in... | ['Abdominal Pain', 'Adrenergic alpha-Antagonists', 'Adult', 'Antiemetics', 'Female', 'Gastric Emptying', 'Gastroparesis', 'Humans', 'Mianserin', 'Mirtazapine', 'Nausea', 'Serotonin 5-HT1 Receptor Antagonists', 'Treatment Outcome', 'Virus Diseases', 'Vomiting'] | 24,914,393 | [['C23.888.592.612.054', 'C23.888.821.030'], ['D27.505.519.625.050.200.100', 'D27.505.696.577.050.200.100'], ['M01.060.116'], ['D27.505.696.663.050.030', 'D27.505.954.427.095', 'D27.505.954.483.200'], ['G10.261.360.400'], ['C06.405.748.543', 'C23.888.592.636.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effect of continuous blood purification on P38MAPK signaling pathway in patients with multiple organ dysfunction syndrome. | OBJECTIVE: The aim of the study was to investigate the role of p38MAPK signaling pathway in patients with multiple organ dysfunction syndrome treated with continuous blood purification.METHODS: Blood samples were obtained to analyze the protein level of inflammatory factors (IL-1, IL-8, IL-10, and TNF-á) and phosphoryl... | ['Adult', 'Caco-2 Cells', 'Case-Control Studies', 'Cytokines', 'Female', 'Hemodiafiltration', 'Humans', 'MAP Kinase Signaling System', 'Male', 'Middle Aged', 'Multiple Organ Failure', 'Nitric Oxide Synthase Type II'] | 30,950,538 | [['M01.060.116'], ['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['E02.870.300.200', 'E02.912.800.200', 'E04.292.471.350'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Modeling electrostatic interactions of baculovirus vectors for ion-exchange process development. | Product-related impurities constitute a major burden in the production of recombinant viral vectors for gene therapy and vaccination; it impairs not only the biological efficacy of the preparation but the process yield/productivity. Recombinant baculovirus was used as an enveloped virus model to address this issue. Giv... | ['Algorithms', 'Animals', 'Baculoviridae', 'Cell Line', 'Chromatography, Ion Exchange', 'Drug Contamination', 'Hydrogen-Ion Concentration', 'Models, Biological', 'Osmolar Concentration', 'Spodoptera', 'Static Electricity', 'Thermodynamics', 'Virion'] | 20,444,457 | [['G17.035', 'L01.224.050'], ['B01.050'], ['B04.280.065', 'B04.525.100'], ['A11.251.210'], ['E05.196.181.400.383'], ['N06.850.360'], ['G02.300'], ['E05.599.395'], ['G02.640'], ['B01.050.500.131.617.720.500.500.937.650.700'], ['G01.358.500.249.820'], ['G01.906'], ['A21.249']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Characterization of an iron-sulfur flavoprotein from Methanosarcina thermophila. | A gene (isf) encoding an iron-sulfur flavoprotein (Isf) from Methanosarcina thermophila was cloned and sequenced. The gene was located directly upstream of the genes (pta and ack) encoding phosphotransacetylase and acetate kinase and is transcribed in the opposite direction. The amino acid sequence deduced from isf con... | ['Archaeal Proteins', 'Bacterial Proteins', 'Base Sequence', 'Carbon Monoxide', 'Cloning, Molecular', 'DNA, Bacterial', 'Electron Transport', 'Flavodoxin', 'Flavoproteins', 'Genes', 'Iron-Sulfur Proteins', 'Methanosarcina', 'Molecular Sequence Data', 'Restriction Mapping', 'Sequence Alignment', 'Sequence Homology, Amin... | 8,798,638 | [['D12.776.090'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['E05.393.220'], ['D13.444.308.212'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['D12.776.097.400', 'D12.776.331.400'], ['D12.776.331'], ['G05.360.340.024.340'], ['D1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Olodaterol shows anti-fibrotic efficacy in in vitro and in vivo models of pulmonary fibrosis. | BACKGROUND AND PURPOSE: Idiopathic pulmonary fibrosis (IPF) is a fatal respiratory disease characterized by excessive fibroblast activation ultimately leading to scarring of the lungs. Although, the activation of â2 -adrenoceptors (â2 -AR) has been shown to inhibit pro-fibrotic events primarily in cell lines, the role ... | ['Administration, Inhalation', 'Adrenergic beta-2 Receptor Agonists', 'Animals', 'Benzoxazines', 'Bronchodilator Agents', 'Cell Line', 'Collagen Type III', 'Disease Models, Animal', 'Fibroblasts', 'Humans', 'Idiopathic Pulmonary Fibrosis', 'Lung', 'Male', 'Mice', 'Mice, Inbred C57BL', 'RNA, Messenger', 'Transforming Gr... | 28,810,065 | [['E02.319.267.050'], ['D27.505.519.625.050.100.200.200', 'D27.505.696.577.050.100.200.200'], ['B01.050'], ['D03.383.533.249', 'D03.633.100.209'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['A11.251.210'], ['D05.750.078.280.300.300', 'D12.776.860.300.250.300.300'], ['C22.232', 'E05.598.500', 'E05.599.395.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Hypertension and the heart]. | Within the latest ten years research in left ventricular hypertrophy as cardiac target organ damage has uncovered its prognostic importance, and studies indicate that treatment with angiotensin II receptor blockade is most effective in reducing left ventricular hypertrophy. In addition, reduction of left ventricular ma... | ['Angiotensin II Type 1 Receptor Blockers', 'Antihypertensive Agents', 'Atrial Fibrillation', 'Cardiovascular Diseases', 'Heart Diseases', 'Heart Failure', 'Humans', 'Hypertension', 'Hypertrophy, Left Ventricular', 'Losartan', 'Prognosis', 'Risk Factors'] | 19,671,394 | [['D27.505.519.162.500'], ['D27.505.954.411.162'], ['C14.280.067.198', 'C23.550.073.198'], ['C14'], ['C14.280'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C14.280.195.400', 'C23.300.775.250.400'], ['D02.455.426.559.389.185.475', 'D03.383.129.308.507', 'D03.383.129.617.467'], [... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
High-resolution 3D volumetric contrast-enhanced MR angiography with a blood pool agent (ferumoxytol) for diagnostic evaluation of pediatric brain arteriovenous malformations. | OBJECTIVE Patients with brain arteriovenous malformations (AVMs) often require repeat imaging with MRI or MR angiography (MRA), CT angiography (CTA), and digital subtraction angiography (DSA). The ideal imaging modality provides excellent vascular visualization without incurring added risks, such as radiation exposure.... | ['Adolescent', 'Angiography, Digital Subtraction', 'Brain', 'Child', 'Child, Preschool', 'Contrast Media', 'Dose-Response Relationship, Drug', 'Female', 'Ferrosoferric Oxide', 'Hematinics', 'Humans', 'Imaging, Three-Dimensional', 'Intracranial Arteriovenous Malformations', 'Magnetic Resonance Angiography', 'Male', 'Ret... | 29,882,734 | [['M01.060.057'], ['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['A08.186.211'], ['M01.060.406'], ['M01.060.406.448'], ['D27.505.259.500', 'D27.720.259'], ['G07.690.773.875', 'G07.690.936.500'], ['D01.490.100.375', 'D01.490.200.350',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Nodular lymphoid hyperplasia in endoscopic and FDG-PET/CT ((18)F-fluoro-2-deoxyglucose positron emission tomography/computerized tomography) imaging. | Gastrointestinal nodular lymphoid hyperplasia is a rare lymphoproliferative state. In children, it is associated with familial immunodeficiency disease but most cases have no obvious etiology. In adults, nodular lymphoid hyperplasia is associated with immunocompromised status, including chemotherapy, acquired immunodef... | ['Adolescent', 'Endoscopy', 'Fluorodeoxyglucose F18', 'Humans', 'Hyperplasia', 'Intestines', 'Lymph Nodes', 'Male', 'Multimodal Imaging', 'Positron-Emission Tomography', 'Radiography', 'Radiopharmaceuticals'] | 23,768,704 | [['M01.060.057'], ['E01.370.388.250', 'E04.502.250'], ['D09.254.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['A03.556.124'], ['A10.549.400', 'A15.382.520.604.412'], ['E01.370.350.567'], ['E01.370.350.350.800.700', 'E01.370.350.600.350.800.399', 'E01.370.350.710.800.399', 'E01.370.350.82... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Induction of cardiac beta-adrenergic receptor kinase 1 in rat heart failure caused by coronary ligation. | Beta-adrenergic receptor kinase 1 (beta ARK1) participates in the desensitization of beta-adrenergic receptors by uncoupling the signal transduction. The present study was designed to examine whether neurohumoral increase is crucial for the activation of beta ARK1 in heart failure. Four weeks after the ligation of rat ... | ['Animals', 'Coronary Vessels', 'Cyclic AMP-Dependent Protein Kinases', 'Enzyme Induction', 'Heart Failure', 'Ligation', 'Male', 'Myocardium', 'Norepinephrine', 'Organ Size', 'Rats', 'Rats, Sprague-Dawley', 'beta-Adrenergic Receptor Kinases'] | 10,371,700 | [['B01.050'], ['A07.015.114.269', 'A07.015.908.194'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['G05.308.320.200'], ['C14.280.434'], ['E04.426'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.31... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pattern of pseudoexfoliation deposits on the lens and their clinical correlation--clinical study and review of literature. | PURPOSE: To study the clinical correlates of pattern of deposits over the lens in patients with pseudoexfoliation syndrome (PXF) or pseudoexfoliation glaucoma.METHODS: This retrospective observational study screened 346 patients with PXF seen in glaucoma clinic of a tertiary hospital from 2011-2013. Details like patter... | ['Aged', 'Exfoliation Syndrome', 'Eye', 'Female', 'Humans', 'Intraocular Pressure', 'Iris', 'Lens, Crystalline', 'Male', 'Middle Aged', 'Retinal Pigments', 'Retrospective Studies'] | 25,478,872 | [['M01.060.116.100'], ['C11.941.375.285'], ['A01.456.505.420', 'A09.371'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['A09.371.060.450', 'A09.371.894.513'], ['A09.371.060.500'], ['M01.060.116.630'], ['D23.767.930'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500'... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Helicobacter pylori infection is strongly associated with gastric and duodenal ulcers in a large prospective study. | BACKGROUND & AIMS: Infection with Helicobacter pylori (H pylori) is a risk factor for peptic ulcer disease (PUD), but there are limited longitudinal data on the associations between infection and incident gastric or duodenal ulcers.METHODS: Information on potential risk factors, lifetime history of PUD, and serologic m... | ['Aged', 'Antibodies, Bacterial', 'Cohort Studies', 'Cross-Sectional Studies', 'Duodenal Ulcer', 'Female', 'Germany', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Incidence', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Prospective Studies', 'Risk Assessment', 'Stomach Ulcer', 'Surveys and Questionna... | 22,230,167 | [['M01.060.116.100'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C06.405.469.275.800.348', 'C06.405.748.586.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Referred pain from intraneural stimulation of muscle fascicles in the median nerve. | Microelectrode recordings were obtained from 118 cutaneous and 26 muscle fascicles in the intact median nerves of healthy human subjects. The exploring electrodes were also used for painful electrical stimulation of the identified fascicles. Cutaneous pain was accurately projected to fields within the median innervatio... | ['Adult', 'Angina Pectoris', 'Diagnosis, Differential', 'Electric Stimulation', 'Female', 'Forearm', 'Humans', 'Male', 'Median Nerve', 'Microelectrodes', 'Middle Aged', 'Muscles', 'Nociceptors', 'Pain', 'Reaction Time', 'Sensory Thresholds', 'Skin'] | 6,709,382 | [['M01.060.116'], ['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['E01.171'], ['E05.723.402'], ['A01.378.800.585'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800.720.050.500'], ['E07.305.250.500'], ['M01.060.116.630'], ['A02.633', 'A10.690'], ['A08.675.650.915.875', 'A08.800.950.875... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Differential distribution of the endoplasmic reticulum network as visualized by the BipA-EGFP fusion protein in hyphal compartments across the septum of the filamentous fungus, Aspergillus oryzae. | We visualized the endoplasmic reticulum (ER) network by expression of the BipA-EGFP fusion protein in the filamentous fungus, Aspergillus oryzae, and focused on the spatial difference of the ER distribution throughout hyphae. The ER formed an interconnected network with motility and displayed a gradient distribution fr... | ['Aspergillus oryzae', 'Cell Division', 'Endoplasmic Reticulum', 'Fungal Proteins', 'Green Fluorescent Proteins', 'HSP70 Heat-Shock Proteins', 'Hyphae', 'Osmotic Pressure', 'Recombinant Fusion Proteins'] | 16,759,887 | [['B01.300.381.081.500'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.284.430.214.190.875.248'], ['D12.776.354'], ['D12.776.532.265'], ['D12.776.580.216.375'], ['A19.687.400'], ['G01.374.715.578', 'G02.640.249', 'G02.723.661'], ['D12.776.828.300']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A review of non-operative treatment of splenic trauma. | From January 1984 to June 1992, a period of 8.5 years, 60 patients with splenic trauma were treated in Lacor Hospital. the spleen trauma was managed conservatively in 47 (78%) of the patients. Of these, 36 of the patients (60%) were not operated upon. Eleven (18%) were operated upon but nine (15%) patients had explorat... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Spleen', 'Splenectomy', 'Uganda', 'Ultrasonography'] | 7,660,479 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Betulinic acid attenuates renal fibrosis in rat chronic kidney disease model. | BACKGROUND: Most chronic kidney diseases (CKDs), regardless of the nature of the initial injury, progress to end-stage renal disease (ESRD) characterized by fibrosis with irreversible loss of tissue and function. Thus, improved and more effective therapies are critical. Betulinic acid (BA), a pentacyclic triterpene is ... | ['Animals', 'Body Weight', 'Fibrosis', 'Gene Expression Regulation', 'Kidney', 'Molecular Structure', 'Organ Size', 'Pentacyclic Triterpenes', 'Rats', 'Renal Insufficiency, Chronic', 'Triterpenes'] | 28,273,641 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C23.550.355'], ['G05.308'], ['A05.810.453'], ['G02.111.570', 'G02.466'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690'], ['D02.455.849.919.530'], ['B... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficient enhancement of ozonation performance via ZVZ immobilized g-C3 | A functional organic-metal composite material zero-valent zinc immobilized graphitic carbon nitride (ZVZ-g-C3N4) was prepared by a fast and facile two-step synthetic approach with an optimal ZVZ content of 5.4 wt%. The structure, surface morphology and chemical composition of the as-synthesized ZVZ-g-C3N4 were characte... | ['Catalysis', 'Environmental Pollutants', 'Graphite', 'Kinetics', 'Nitriles', 'Oxidation-Reduction', 'Ozone', 'Spectroscopy, Fourier Transform Infrared', 'Surface Properties', 'Zinc'] | 29,704,844 | [['G02.130'], ['D27.888.284'], ['D01.268.150.300', 'D01.578.300'], ['G01.374.661', 'G02.111.490'], ['D02.626'], ['G02.700', 'G03.295.531'], ['D01.362.670.600'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['G02.860'], ['D01.268.556.940', 'D01.268.956.906', 'D01.552.544.940']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Channel specificity and secondary structure of the glucose-inducible porins of Pseudomonas spp. | The OprB porin-mediated glucose transport system was investigated in Pseudomonas chlororaphis, Burkholderia cepacia, and Pseudomonas fluorescens. Kinetic studies of [U-14C]glucose uptake revealed an inducible system of low Km values (0.3-5 microM) and high specificity for glucose. OprB homologs were purified and recons... | ['Bacterial Proteins', 'Burkholderia cepacia', 'Carbohydrate Metabolism', 'Diffusion', 'Glucose', 'Periplasm', 'Porins', 'Protein Structure, Secondary', 'Pseudomonas', 'Pseudomonas fluorescens'] | 9,733,092 | [['D12.776.097'], ['B03.660.075.090.688.100.110.500'], ['G02.111.158', 'G03.191'], ['G01.202', 'G02.196'], ['D09.947.875.359.448'], ['A11.284.295.680'], ['D12.776.157.530.400.500', 'D12.776.543.550.450.730', 'D12.776.543.585.400.730'], ['G02.111.570.820.709.600'], ['B03.440.400.425.625.625', 'B03.660.250.580.590'], ['B... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of effector cells with anti-Candida activity obtained from murine bone marrow cells cultured in the presence of rhG-CSF: comparison between normal and CY-treated mice. | Bone marrow cells (BMC) obtained from normal and cyclophosphamide (CY)-treated mice were cultured in the presence of recombinant human granulocyte-colony stimulating factor (rhG-CSF) and their effector cell activities inhibiting growth of C. albicans were examined. When BMC from CY-treated mice were preincubated with 0... | ['Animals', 'Apoptosis', 'Bone Marrow Cells', 'Candida albicans', 'Cells, Cultured', 'Colony Count, Microbial', 'Cyclophosphamide', 'DNA Fragmentation', 'Female', 'Granulocyte Colony-Stimulating Factor', 'Granulocytes', 'Humans', 'Immunosuppressive Agents', 'Mice', 'Mice, Inbred ICR', 'Monocytes', 'Recombinant Proteins... | 16,172,536 | [['B01.050'], ['G04.146.954.035'], ['A11.148', 'A15.378.316'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['A11.251'], ['E01.370.225.875.220', 'E05.200.875.220'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['G05.200.230'], ['D12.644.276.374.410.240.350', 'D12.776.395.240.200... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Augmented Association Between Blood Pressure and Proteinuria in Hyperuricemic Patients With Nonnephrotic Chronic Kidney Disease. | BACKGROUND: Hyperuricemia (HU) may enhance susceptibility to hypertensive renal damage via disrupted autoregulation of glomerular hemodynamics. The effect of HU on the association between blood pressure (BP) and proteinuria remains unknown in patients with chronic kidney disease (CKD).METHODS: In total, 109 patients wi... | ['Adult', 'Antihypertensive Agents', 'Biomarkers', 'Blood Pressure', 'Cross-Sectional Studies', 'Female', 'Glomerular Filtration Rate', 'Gout Suppressants', 'Humans', 'Hypertension', 'Hyperuricemia', 'Japan', 'Kidney', 'Male', 'Middle Aged', 'Prevalence', 'Prognosis', 'Proteinuria', 'Renal Insufficiency, Chronic', 'Ris... | 28,927,237 | [['M01.060.116'], ['D27.505.954.411.162'], ['D23.101'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.390.400.300', 'G08.852.357'], ['D27.505.954.329.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C23.550.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cytoplasmic expression of mature glycylglycine endopeptidase lysostaphin with an amino terminal hexa-histidine in a soluble and catalytically active form in Escherichia coli. | Methicillin-resistant Staphylococcus aureus is a major problem in the world, causing hospital acquired infections and the infections/pathogenesis in community. Lysostaphin is a novel therapeutic molecule to kill the multidrug-resistant S. aureus. Mature lysostaphin is a single polypeptide (approximately 27 kDa) chain m... | ['Amino Acid Sequence', 'Catalysis', 'Cloning, Molecular', 'Cytoplasm', 'Enzyme Activation', 'Escherichia coli', 'Gene Expression Regulation, Enzymologic', 'Histidine', 'Hydrogen-Ion Concentration', 'Lysostaphin', 'Molecular Sequence Data', 'Molecular Weight', 'Phylogeny', 'Recombinant Fusion Proteins', 'Solubility', '... | 16,181,789 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.130'], ['E05.393.220'], ['A11.284.430.214'], ['G02.111.263', 'G03.328'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.308.320'], ['D12.125.072.329', 'D12.125.142.308'], ['G02.300'], ['D08.811.277.656.300.480.452', 'D08.811.277.656.675.374.452'], ['L01.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Experiences from an international tele-epilepsy collaboration. | OBJECTIVE: Our main objective was to use videoconferencing as a primary means to: a) assist in launching an epilepsy surgery program in Pakistan; 2) participate in case conferences on complex epilepsy patients in each country.METHODS: Extensive testing using both point to point and bridged integrated service digital ne... | ['Adult', 'Computer-Assisted Instruction', 'Electroencephalography', 'Epilepsy', 'Female', 'Follow-Up Studies', 'Humans', 'International Cooperation', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Pakistan', 'Retrospective Studies', 'Videoconferencing', 'Young Adult'] | 19,831,126 | [['M01.060.116'], ['I02.903.771.500.208'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615.500'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['Z01.252.245... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
[Tuberculosis in patients with malignant neoplasms]. | Out of 810 patients autopsied at our institute between 1972 and 1985, tuberculosis was demonstrated in 12 (1.5%), all between 40 and 80 years of age, regardless of cancer type. Of 4,272 patients who underwent surgery for malignant neoplasms, 481 were examined for M. tuberculosis by culture in different specimens. All o... | ['Adult', 'Age Factors', 'Aged', 'Antitubercular Agents', 'Drug Resistance, Microbial', 'Female', 'Humans', 'Lung Neoplasms', 'Lymphoma', 'Male', 'Middle Aged', 'Mycobacterium tuberculosis', 'Neoplasms', 'Tuberculosis', 'Tuberculosis, Pulmonary'] | 3,086,596 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['D27.505.954.122.085.255'], ['G06.225', 'G07.690.773.984.269'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.557.386', 'C15.604.515.569', 'C20.683.515.761'], ['M01.060.116.630... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transient cholestatic hepatitis in a neonate associated with carbamazepine exposure during pregnancy and breast-feeding. | We report a 3-week-old boy with cholestatic hepatitis, most likely due to carbamazepine exposure during pregnancy and breastfeeding. Cholestasis resolved after cessation of nursing. Liver function test results and histological findings were compatible with a drug-induced hepatitis. Other causes were excluded. While car... | ['Breast Feeding', 'Carbamazepine', 'Chemical and Drug Induced Liver Injury', 'Epilepsy', 'Female', 'Humans', 'Infant, Newborn', 'Jaundice, Neonatal', 'Liver', 'Male', 'Pregnancy', 'Pregnancy Complications', 'Prenatal Exposure Delayed Effects'] | 2,279,511 | [['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['D03.633.300.240.127'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614.451.500', 'C23.550.429.249.500'], ['A03.620'], ['G08.686... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The utilization of an estrogen assay system in obstetric practice. | Subsequent to reviewing 626 perinatal deaths in relation to estrogen assay, 1500 consecutive pregnancies were analyzed in detail in regard to utilization of urinary estrogen assays. 2710 assays were performed on 456 cases. The perinatal mortality rate in this high-risk group was 8.8 per 1000 compared with the overall h... | ['Cost-Benefit Analysis', 'Estrogens', 'Female', 'Fetal Death', 'Fetal Monitoring', 'Humans', 'Placental Insufficiency', 'Pregnancy'] | 6,781,944 | [['N03.219.151.125'], ['D27.505.696.399.472.277'], ['C13.703.223', 'C23.550.260.585'], ['E01.370.378.230', 'E01.370.520.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.703.590.800'], ['G08.686.784.769']] | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Postreceptor signalling of growth hormone and prolactin and their effects in the differentiated insulin-secreting cell line, INS-1. | Signal transduction of two mitogens for pancreatic beta-cells, GH and PRL, was investigated using the differentiated insulin-secreting cell line, INS-1. Addition of human GH (hGH) or ovine PRL in a serum-substitute medium increased growth, insulin content, and nutrient metabolism evaluated by tetrazolium salt reduction... | ['Animals', 'Calcium', 'Cattle', 'Cell Line', 'Culture Media', 'Cyclic AMP', 'Cyclic AMP-Dependent Protein Kinases', 'DNA', 'Enzyme Activation', 'Enzyme Inhibitors', 'Growth Hormone', 'Humans', 'Insulin', 'Insulin Secretion', 'Janus Kinase 2', 'Phenols', 'Phosphotyrosine', 'Prolactin', 'Protein-Tyrosine Kinases', 'Prot... | 8,612,523 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251.210'], ['D27.720.470.305', 'E07.206'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Toxoplasma gondii phosphoinositide phospholipase C (TgPI-PLC) with high affinity for phosphatidylinositol. | The Toxoplasma gondii phosphoinositide-specific phospholipase C gene (TgPI-PLC) was cloned, sequenced and expressed in Escherichia coli and its enzymatic characteristics were investigated. TgPI-PLC is present in the genome as a single-copy gene consisting of 22 exons interrupted by 21 introns, and encodes a polypeptide... | ['Amino Acid Sequence', 'Animals', 'Calcium', 'Enzyme Stability', 'Gene Expression Regulation', 'Hydrogen-Ion Concentration', 'Magnesium', 'Molecular Sequence Data', 'Phosphatidylinositol Diacylglycerol-Lyase', 'Phosphatidylinositols', 'Phosphoinositide Phospholipase C', 'Protein Transport', 'Substrate Specificity', 'T... | 16,288,600 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.916.360', 'G02.111.700.500'], ['G05.308'], ['G02.300'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['L01.453.245.667'], ['D08.811.277.352.640.700.700.500', 'D08.811.520.650.800'], ['D10... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
PMI40, an intron-containing gene required for early steps in yeast mannosylation. | We have previously described a temperature-sensitive pmi40-1 mutant of Saccharomyces cerevisiae which is defective in glycosylation and secretion because of a thermolabile phosphomannose isomerase (PMI) activity. Inactivation of PMI at the restrictive temperature of 37 degrees C prevents synthesis of the GDP-mannose an... | ['Amino Acid Sequence', 'Base Sequence', 'Chromosomes, Fungal', 'DNA Mutational Analysis', 'Dolichol Monophosphate Mannose', 'Gene Expression Regulation, Fungal', 'Genetic Complementation Test', 'Glycosylation', 'Guanosine Diphosphate Mannose', 'Introns', 'Mannose', 'Mannose-6-Phosphate Isomerase', 'Molecular Sequence ... | 1,377,774 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.187.360', 'A19.311', 'G05.360.162.360'], ['E05.393.760.700.300'], ['D02.455.849.690.700.700.250', 'D09.894.680.700.250', 'D10.390.700.700.250'], ['G05.308.330'], ['E05.393.281.526'], ['G02.111.158.812', 'G0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Exposure to ayahuasca induces developmental and behavioral alterations on early life stages of zebrafish. | Ayahuasca is a psychoactive concoction prepared from the plants Banisteriopsis caapi and Psychotria viridis which are used ancestrally by Amazonian Indian populations and more recently, by Christian religious groups in Brazil and other countries. The aims of the present study were to identify the effects of ayahuasca o... | ['Animals', 'Banisteriopsis', 'Behavior, Animal', 'Embryo, Nonmammalian', 'Embryonic Development', 'Erythrocytes', 'Larva', 'Life Cycle Stages', 'Locomotion', 'Plant Extracts', 'Zebrafish'] | 30,086,270 | [['B01.050'], ['B01.650.940.800.575.912.250.859.797.690.099'], ['F01.145.113'], ['A13.350', 'A16.331'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B05.500.500', 'G07.345.500.550.500.500'], ['B05.500', 'G07.345.500.550.500'], ['G07.568.500', 'G11.427.410.568'], [... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exogenous FABP4 increases breast cancer cell proliferation and activates the expression of fatty acid transport proteins. | Adipose tissue plays an important role in tumor progression, because it provides nutrients and adipokines to proliferating cells. Fatty acid binding protein 4 (FABP4) is a key adipokine for fatty acid transport. In metabolic pathologies, plasma levels of FABP4 are increased. However, the role of this circulating protei... | ['Breast', 'Breast Neoplasms', 'Cell Movement', 'Cell Proliferation', 'Disease Progression', 'Fatty Acid Transport Proteins', 'Fatty Acid-Binding Proteins', 'Female', 'Humans', 'MAP Kinase Signaling System', 'MCF-7 Cells', 'Proto-Oncogene Proteins c-akt', 'Signal Transduction'] | 27,061,264 | [['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C23.550.291.656'], ['D12.776.157.530.300', 'D12.776.543.585.300'], ['D12.776.157.170'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['A11.25... | ['Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Encephalitogenic T lymphocytes develop from SJL/J hematopoietic cells transplanted into severe combined immunodeficient (SCID) mice. | Previously, we constructed chimeras by injecting hematopoietic cells from experimental autoimmune encephalomyelitis (EAE)-susceptible SJL (H-2s) strain mice into severe combined immunodeficient (SCID) C.B-17scid/scid (H-2d) mice. These SCID mouse-SJL mouse hematopoietic cell chimeras developed passive EAE following ado... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cell Line', 'Chimera', 'Encephalomyelitis, Autoimmune, Experimental', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Immunotherapy, Adoptive', 'Mice', 'Mice, SCID', 'Molecular Sequence Data', 'Myelin Proteins', 'Myelin Proteolipid Protein', 'T-Lymphocytes'] | 7,535,789 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['B05.200'], ['C10.114.703.300', 'C10.228.140.695.562.250', 'C10.314.350.250', 'C20.111.258.625.300', 'E05.598.500.500.500'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.05... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Electron microscopic study of Bacillus subtilis protoplast fusion. | When protoplasts derived from sporulating cells of Bacillus subtilis were fused by exposure to polyethylene glycol (PEG) and fixed immediately thereafter, protoplasts with two enclosed prespores could be seen by electron microscope. The number of fusion events was greatly increased, and multiply fused protoplasts appea... | ['Bacillus subtilis', 'Microscopy, Electron', 'Polyethylene Glycols', 'Protoplasts', 'Recombination, Genetic', 'Spores, Bacterial'] | 108,247 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Homonuclear internuclear double resonance spectroscopy as a basis for determination of amino acid conformation. | INDOR (Internuclear Double Resonance) spectroscopy is shown to be superior to conventional (spectra obtained not by sweeping, but by maintaining constant the decoupling frequency) nuclear single- or double-resonance techniques for conformational studies of amino acids and amino acid residues in the following ways: (a) ... | ['Amino Acids', 'Chemical Phenomena', 'Chemistry', 'Magnetic Resonance Spectroscopy', 'Methods', 'Phenylalanine', 'Protein Conformation', 'Threonine', 'Valine'] | 4,504,338 | [['D12.125'], ['G02'], ['H01.181'], ['E05.196.867.519'], ['E05.581'], ['D12.125.072.050.685', 'D12.125.142.666'], ['G02.111.570.820.709'], ['D12.125.142.815', 'D12.125.154.900'], ['D12.125.070.950', 'D12.125.142.930']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Regulation of ceruloplasmin activity in oncogynecological diseases]. | Serum ceruloplasmih (CP) and anti-CP antibody levels were studied by the oxidase method in 18 healthy women and in 86 women with gynecological tumors. The results demonstrate that: 1) Serum CP concentrations increased in endometrial and ovarian cancer, in benign ovarian tumors and to a lesser extent in mioma of uterus.... | ['Biomarkers, Tumor', 'Ceruloplasmin', 'Endometrial Neoplasms', 'Female', 'Humans', 'Leiomyoma', 'Ovarian Neoplasms', 'Uterine Neoplasms'] | 12,506,616 | [['D23.101.140'], ['D08.811.682.226', 'D12.776.124.050.130', 'D12.776.124.790.106.214', 'D12.776.157.160', 'D12.776.377.715.085.214', 'D12.776.556.151'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.590.450'], ['C04.588... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mental visualization of objects from cross-sectional images. | We extended the classic anorthoscopic viewing procedure to test a model of visualization of 3D structures from 2D cross-sections. Four experiments were conducted to examine key processes described in the model, localizing cross-sections within a common frame of reference and spatiotemporal integration of cross sections... | ['Female', 'Humans', 'Male', 'Orientation', 'Pattern Recognition, Visual', 'Photic Stimulation', 'Psychomotor Performance', 'Reaction Time', 'Space Perception', 'Transducers', 'Visual Perception', 'Young Adult'] | 22,217,386 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.058.577', 'F02.830.606'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E05.723.729'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.463.593.778'], ['E07.305.812'], ['F02.463.593.932'], ['M01.060... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Impact of community-directed treatment on soil transmitted helminth infections in children aged 12 to 59 months in Mazabuka District, Zambia. | This study assessed the impact of adding community-directed treatment (ComDT) to the routine health facility (HF)-based treatment on prevalence and intensity of soil transmitted helminth (STH) infections among children aged 12 to 59 months. Repeated cross-sectional surveys were conducted among randomly selected childre... | ['Age Distribution', 'Ancylostomatoidea', 'Animals', 'Anthelmintics', 'Ascariasis', 'Ascaris lumbricoides', 'Child Welfare', 'Child, Preschool', 'Community Health Services', 'Cross-Sectional Studies', 'Data Collection', 'Follow-Up Studies', 'Hookworm Infections', 'Humans', 'Infant', 'Mebendazole', 'Parasite Egg Count',... | 21,320,386 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['B01.050.500.500.294.400.968.100'], ['B01.050'], ['D27.505.954.122.250.075'], ['C01.610.335.508.700.100.070'], ['B01.050.500.500.294.400.500.100.108.425'], ['I01.880.787.293'], ['M01.060.406.448'], ['N02.421.143'], ['E05.318.372.500.875', 'N05.715.360.330.500.875... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Assessing the spatial nonstationarity in relationship between local patterns of HIV infections and the covariates in South Africa: A geographically weighted regression analysis. | Beyond the structural drivers such as distance from the road, rural/urban divide or demographic profiles, not much is known about the spatial relationship between HIV and social covariates. Spatial relations between social covariates and HIV infection of persons above 15 years were explored and mapped using geographica... | ['Adult', 'Female', 'Geographic Mapping', 'HIV Infections', 'Humans', 'Intergenerational Relations', 'Male', 'Middle Aged', 'Prevalence', 'Rural Population', 'Sexual Behavior', 'Sexual Partners', 'Socioeconomic Factors', 'South Africa', 'Spatial Regression', 'Urban Population'] | 26,919,758 | [['M01.060.116'], ['E05.318.389', 'E05.318.740.933.249', 'N05.715.360.750.746.249', 'N06.850.520.830.933.249'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.370.110', 'F01.829.40... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[A Mirror Image of a Tiny Distal Anterior Cerebral Artery Aneurysm that Ruptured]. | Distal anterior cerebral artery(DACA)aneurysms have a low incidence. Particularly, DACA mirror aneurysms are extremely rare, although DACA multiple aneurysms are not rare. Generally, it is said that tiny aneurysms have a low risk of rupture. However, we sometimes encounter cases of ruptured tiny aneurysm. We describe a... | ['Aneurysm, Ruptured', 'Angiography, Digital Subtraction', 'Anterior Cerebral Artery', 'Cerebral Angiography', 'Humans', 'Intracranial Aneurysm', 'Subarachnoid Hemorrhage'] | 30,369,492 | [['C14.907.055.185'], ['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['A07.015.114.228.100'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
99mTc-d,l-HMPAO and SPECT of the brain in normal aging. | Single photon emission computed tomography (SPECT) with 99mTc-d,l-hexamethylpropyleneamine oxime (99mTc-d,l-HMPAO) was used to determine global and regional CBF in 53 healthy subjects aged 21-83 years. For the whole group, global CBF normalized to the cerebellum was 86.4% +/- 8.4 (SD). The contribution of age, sex, and... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aging', 'Atrophy', 'Brain', 'Cerebellum', 'Cerebral Cortex', 'Cerebrovascular Circulation', 'Female', 'Frontal Lobe', 'Humans', 'Male', 'Middle Aged', 'Organotechnetium Compounds', 'Oximes', 'Technetium Tc 99m Exametazime', 'Tomography, Emission-Computed, Single-Photon', 'Xenon R... | 2,016,360 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['C23.300.070'], ['A08.186.211'], ['A08.186.211.132.810.428.200'], ['A08.186.211.200.885.287.500'], ['G09.330.100.159'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.691.8... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Isolated P/Q Calcium Channel Deletion in Layer VI Corticothalamic Neurons Generates Absence Epilepsy. | UNLABELLED: Generalized spike-wave seizures involving abnormal synchronization of cortical and underlying thalamic circuitry represent a major category of childhood epilepsy. Inborn errors of Cacna1a, the P/Q-type voltage-gated calcium channel á subunit gene, expressed throughout the brain destabilize corticothalamic r... | ['Animals', 'Anticonvulsants', 'Calcium Channels, N-Type', 'Disease Models, Animal', 'Epilepsy, Absence', 'Ethosuximide', 'Excitatory Postsynaptic Potentials', 'Female', 'Luminescent Proteins', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Motor Disorders', 'Mutation', 'Neurons', 'Reaction Time', 'Receptor... | 26,758,833 | [['B01.050'], ['D27.505.954.427.080'], ['D12.776.157.530.400.150.585', 'D12.776.543.550.450.150.585', 'D12.776.543.585.400.150.585'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.228.140.490.375.260', 'C10.228.140.490.493.125'], ['D02.478.770.333', 'D03.383.773.812.852.333'], ['G04.580.887.249', 'G07.265.675.88... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A coupled subsample displacement estimation method for ultrasound-based strain elastography. | Obtaining accurate displacement estimates along both axial (parallel to the acoustic beam) and lateral (perpendicular to the beam) directions is an important task for several clinical applications such as shear strain imaging, modulus reconstruction and temperature imaging, where a full description of the two or three-... | ['Algorithms', 'Biomechanical Phenomena', 'Breast Neoplasms', 'Computer Simulation', 'Elasticity Imaging Techniques', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Mammography', 'Motion', 'Phantoms, Imaging', 'Stress, Mechanical', 'Ultrasonography, Mammary'] | 26,458,219 | [['G17.035', 'L01.224.050'], ['G01.154.090', 'G01.374.089'], ['C04.588.180', 'C17.800.090.500'], ['L01.224.160'], ['E01.370.350.850.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.700.500'], ['G01.482'], ['E07.671'], ['G01.374.835'], ['E01.370.350.850.860', 'E01.370.378.850']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The protein kinase Pstol1 from traditional rice confers tolerance of phosphorus deficiency. | As an essential macroelement for all living cells, phosphorus is indispensable in agricultural production systems. Natural phosphorus reserves are limited, and it is therefore important to develop phosphorus-efficient crops. A major quantitative trait locus for phosphorus-deficiency tolerance, Pup1, was identified in t... | ['Adaptation, Physiological', 'Breeding', 'Droughts', 'Genes, Plant', 'Genome, Plant', 'Molecular Sequence Data', 'Oryza', 'Phosphorus', 'Plant Proteins', 'Plant Roots', 'Plants, Genetically Modified', 'Protein Kinases', 'Quantitative Trait Loci'] | 22,914,168 | [['G07.025', 'G16.012.500'], ['E05.820.150', 'G05.090'], ['G16.500.175.781', 'G16.500.750.775.154', 'N06.230.100.230.150'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.360.340.365'], ['L01.453.245.667'], ['B01.650.940.800.575.912.250.822.616'], ['D01.268.666'], ['D12.776.765'], ['A18.400'], ['B01.650.520'... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Treatment of ureteral colic with intravenous indomethacin. | A randomized prospective double-blind study of the analgesic effect of 50 mg. intravenous indomethacin, a prostaglandin synthesis inhibitor, was done on 47 consecutive patients with acute ureteral colic. The placebo used was 5 mg. intravenous riboflavin because of the same color as indomethacin. Indomethacin provided c... | ['Clinical Trials as Topic', 'Colic', 'Double-Blind Method', 'Humans', 'Indomethacin', 'Kidney', 'Prospective Studies', 'Ureter', 'Ureteral Diseases'] | 366,182 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['C16.614.166'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.420'], ['A05.810.453'], ['E05.318.372.500.750.625', 'N05.715.360.330.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
B chromosomes in Nierembergia aristata (Solanaceae): nucleolar activity and competition with the A chromosomes. | B chromosomes are additional dispensable chromosomes that may be present in some individuals, populations, or species, which have probably arisen from the A chromosomes but follow their own evolutionary pathway. Supposedly, B chromosomes do not contain major genes except for ribosomal DNA (rDNA) sequences that have bee... | ['Cell Nucleolus', 'Chromosomes, Plant', 'In Situ Hybridization, Fluorescence', 'Metaphase', 'Solanaceae'] | 20,924,164 | [['A11.284.430.106.279.345.175'], ['A11.284.187.560', 'A18.005', 'G05.360.162.560'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350', 'E05.200.750.600.670.325.350', 'E05.393.285.350', 'E05.393.661.475.350'], ['G04.144.220.220.687.625', 'G04.144.220.220.781.625', 'G05... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Androgen receptor as a regulator of ZEB2 expression and its implications in epithelial-to-mesenchymal transition in prostate cancer. | Zinc finger E-box-binding protein 2 (ZEB2) is known to help mediate the epithelial-to-mesenchymal transition, and thereby it facilitates cancer metastasis. This study was initiated to explore whether ZEB2 expression differs in prostate cancer (PCa, n=7) and benign prostatic hyperplasia (BPH, n=7) tissues. In PCa tissue... | ['Androgens', 'Apoptosis', 'Blotting, Western', 'Cell Movement', 'Cell Proliferation', 'Dihydrotestosterone', 'Epithelial-Mesenchymal Transition', 'Fluorescent Antibody Technique', 'Gene Expression Regulation, Neoplastic', 'Homeodomain Proteins', 'Humans', 'Immunoenzyme Techniques', 'Male', 'MicroRNAs', 'Neoplasms, Hor... | 24,812,058 | [['D27.505.696.399.472.161'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D04.210.500.054.040.248', 'D06.472.334.851.968.964'], ['G04.356.500'], ['E01.370.225.500.607.5... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ab initio and DFT studies of the molecular structures and vibrational spectra of succinonitrile. | The Molecular structure, conformational stability and vibrational frequencies of succinonitrile NCCH2CH2CN have been investigated with ab initio and density functional theory (DFT) methods implementing the standard 6-311++G* basis set. The potential energy surfaces (PES) have been explored at DFT-B3LYP, HF and MP2 leve... | ['Models, Chemical', 'Molecular Conformation', 'Nitriles', 'Spectrophotometry, Infrared', 'Spectrum Analysis, Raman', 'Thermodynamics', 'Vibration'] | 16,872,884 | [['E05.599.495'], ['G02.111.570.820'], ['D02.626'], ['E05.196.712.726.676', 'E05.196.867.826.676'], ['E05.196.822.860', 'E05.196.867.890'], ['G01.906'], ['G01.374.930']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Facile surface functionalization of upconversion nanoparticles with phosphoryl pillar[5]arenes for controlled cargo release and cell imaging. | Upon surface functionalization and stabilization of â-NaYF4:Yb/Er upconversion nanoparticles (UCNPs) with phosphoryl pillar[5]arenes (PP5) via a facile ligand exchange method, we constructed a new hybrid material (PP5-UCNPs) with good water dispersibility especially in a physiological environment and superior capabilit... | ['Anti-Inflammatory Agents, Non-Steroidal', 'Calixarenes', 'Cell Line', 'Drug Carriers', 'Drug Liberation', 'Erbium', 'Fluorides', 'Humans', 'Hydrogen-Ion Concentration', 'Infrared Rays', 'Macrophages', 'Mesalamine', 'Microscopy, Fluorescence', 'Nanoparticles', 'Particle Size', 'Phosphorous Acids', 'Quaternary Ammonium... | 30,387,478 | [['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D04.345.025'], ['A11.251.210'], ['D26.255.260', 'E02.319.300.380'], ['G02.211', 'G03.787.321', 'G07.690.725.321'], ['D01.268.558.362.437', 'D01.552.550.399.437'], ['D01.248.497.158.380', 'D01.303.350.300'], ['B01.050.150.900.649.313.9... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Primitive erythropoiesis in the Xenopus embryo: the synergistic role of LMO-2, SCL and GATA-binding proteins. | Hematopoietic stem cells are derived from ventral mesoderm during vertebrate development. Gene targeting experiments in the mouse have demonstrated key roles for the basic helix-loop-helix transcription factor SCL and the GATA-binding protein GATA-1 in hematopoiesis. When overexpressed in Xenopus animal cap explants, S... | ['Adaptor Proteins, Signal Transducing', 'Amino Acid Sequence', 'Animals', 'Basic Helix-Loop-Helix Transcription Factors', 'Bone Morphogenetic Protein 4', 'Bone Morphogenetic Proteins', 'Cloning, Molecular', 'DNA-Binding Proteins', 'Erythroid-Specific DNA-Binding Factors', 'Erythropoiesis', 'GATA1 Transcription Factor'... | 11,493,549 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.260.103', 'D12.776.930.125'], ['D12.644.276.954.200.400', 'D12.776.467.942.200.400', 'D23.529.942.200.400'], ['D12.644.276.954.200', 'D12.776.467.942.200', 'D23.529.942.200'], ['E05.393.220'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Phosphorus: a rate limiting nutrient in surface waters. | Phosphorus is an essential element for all life forms. It is a mineral nutrient. Orthophosphate is the only form of P that autotrophs can assimilate. Extracellular enzymes hydrolyze organic forms of P to phosphate. Eutrophication is the over-enrichment of surface waters with mineral nutrients. The results are excessive... | ['Agriculture', 'Animals', 'Environmental Monitoring', 'Eutrophication', 'Fertilizers', 'Food Chain', 'Phosphorus', 'Water Pollutants, Chemical'] | 10,228,963 | [['J01.040'], ['B01.050'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G16.500.285'], ['D27.720.031.400'], ['G16.500.275.157.250', 'N06.230.124.250'], ['D01.268.666'], ['D27.888.284.903.655']] | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Contrasting bacterial communities in two indigenous Chionochloa (Poaceae) grassland soils in New Zealand. | The cultivation of grasslands can modify both bacterial community structure and impact on nutrient cycling as well as the productivity and diversity of plant communities. In this study, two pristine New Zealand grassland sites dominated by indigenous tall tussocks (Chionochloa pallens or C. teretifolia) were examined t... | ['Acidobacteria', 'Actinobacteria', 'Biodiversity', 'Carbon', 'DNA, Bacterial', 'Grassland', 'New Zealand', 'Nitrogen', 'Phosphorus', 'Poaceae', 'Proteobacteria', 'RNA, Ribosomal, 16S', 'Soil', 'Soil Microbiology'] | 28,658,306 | [['B03.026', 'B03.440.400.050'], ['B03.510.024', 'B03.510.460.400.400.049'], ['G16.500.275.157.049', 'N06.230.124.049'], ['D01.268.150'], ['D13.444.308.212'], ['G16.500.275.157.531', 'N06.230.124.390'], ['Z01.639.760.747', 'Z01.678.100.747'], ['D01.268.604', 'D01.362.625'], ['D01.268.666'], ['B01.650.940.800.575.912.25... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Cine-fluoroscopic studies of ureteral function in the human renal transplant. | During a 14-month period 73 satisfactory fluoroscopic studies were done on 59 kidney transplant recipients. Ureteral peristalsis was seen in 90 per cent of these studies and there was no difference between patients receiving living related donor kidneys and those receiving cadaveric kidneys. When ureteral activity was ... | ['Cineradiography', 'Creatinine', 'Graft Rejection', 'Humans', 'Kidney', 'Kidney Transplantation', 'Time Factors', 'Transplantation, Homologous', 'Ureter', 'Urinary Tract Infections'] | 1,095,785 | [['E01.370.350.700.225.469'], ['D03.383.129.308.207'], ['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['G01.910.857'], ['E04.936.864'], ['A05.810.776'], ['C01.915', 'C12.777.892', 'C13.351.968.892']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spatial features for Escherichia coli genome organization. | BACKGROUND: In bacterial genomes, the compactly encoded genes and operons are well organized, with genes in the same biological pathway or operons in the same regulon close to each other on the genome sequence. In addition, the linearly close genes have a higher probability of co-expression and their protein products t... | ['Escherichia coli', 'Gene Expression Regulation, Bacterial', 'Genome, Bacterial', 'Operon', 'Protein Interaction Maps'] | 25,652,224 | [['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.308.300'], ['G05.360.340.358.207'], ['G05.360.340.024.686', 'G05.360.340.358.207.500'], ['G03.493.750']] | ['Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative study of out-reach immunization strategies in rural area. | Efficiency of out-reach immunization strategies operationalised in a rural area of district Ambala (Haryana) was evaluated. Till year 1984-85 immunization delivery was 'sporadic'. Annual cluster immunization campaigns were conducted during 1985-86 and 1986-87. This comprised of delivery of oral polio vaccine (OPV) and/... | ['Child, Preschool', 'Female', 'Humans', 'Immunization', 'Immunization Schedule', 'India', 'Infant', 'Infant, Newborn', 'Male', 'Pregnancy', 'Preventive Health Services', 'Rural Population', 'Vaccination'] | 2,081,638 | [['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['E02.095.465.425.400.470', 'E05.478.550.545'], ['Z01.252.245.393'], ['M01.060.703'], ['M01.060.703.520'], ['G08.686.784.769'], ['N02.421.72... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Viscoelasticity of hyaluronic acid with different molecular weights. | Storage and loss moduli of hyaluronic acid solutions with different molecular weights were observed as a function of frequency in the presence of sugars and salts. The hyaluronic acid solutions of higher molecular weight (Mw > 17 x 10(6)) fractions showed entanglement, whereas lower molecular weight fractions did not. ... | ['Carbohydrates', 'Elasticity', 'Electrochemistry', 'Hyaluronic Acid', 'Hydrogen Bonding', 'In Vitro Techniques', 'Molecular Weight', 'Rheology', 'Salts', 'Solutions', 'Viscosity'] | 8,729,484 | [['D09'], ['G01.374.590'], ['H01.181.529.307'], ['D09.698.373.475'], ['G02.282'], ['E05.481'], ['G02.494'], ['E05.830', 'H01.671.808'], ['D01.786'], ['D26.776'], ['G02.930']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
The effects of intraventricular prolactin infusions on pituitary responsiveness to thyrotropin-releasing hormone, 5-hydroxytryptophan or morphine in rhesus monkeys. | The effects of intraventricular infusions of ovine prolactin (oPrl) on both endogenous prolactin levels in serum, and upon the release of prolactin and cortisol in response to treatment with either TRH, 5-HTP or morphine were studied in rhesus monkeys. A single injection of oPrl (10.8 micrograms) into the lateral ventr... | ['5-Hydroxytryptophan', 'Animals', 'Carbidopa', 'Castration', 'Estradiol', 'Female', 'Hydrocortisone', 'Kinetics', 'Macaca mulatta', 'Male', 'Morphine', 'Pituitary Gland', 'Prolactin', 'Sheep', 'Thyrotropin-Releasing Hormone'] | 6,402,265 | [['D12.125.072.050.850.479'], ['B01.050'], ['D02.092.311.200.538.200', 'D02.442.200', 'D02.455.426.559.389.657.166.175.200.538.200'], ['E04.270.282', 'E04.950.165'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['G01.374.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of marketing claims, ingredients, and nutrient profiles of over-the-counter diets marketed for skin and coat health of dogs. | OBJECTIVE: To evaluate marketing claims, ingredients, and nutrient profiles of over-the-counter diets marketed for skin and coat health of dogs.DESIGN: Cross-sectional study.SAMPLE: 24 over-the-counter dry and canned diets marketed for skin and coat health of dogs.PROCEDURES: Data on marketing claims and ingredients we... | ['Advertising', 'Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Diet', 'Dogs', 'Hair', 'Nutritive Value', 'Pets', 'Skin Physiological Phenomena'] | 26,043,131 | [['J01.219.687.274', 'L01.143.050'], ['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['G07.203.650.240'], ['B01.050.150.900.649.313.750.250.216.200'], ['A17.360'], ['G07.203.650.660', 'J01.576.423.850.730.750', 'N06.850.601.750'], ['B01.050.050.116.600'], ['G13.750']] | ['Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Hypoxic and hypoglycaemic changes of intracellular pH in cerebral cortical pyramidal neurones. | Intracellular pH and membrane potential were measured during hypoxia and/or hypoglycaemia in cortical pyramidal neurones of a rat cortical slice preparation. Intracellular pH (pHi) was calculated from ratiometric microfluorometry of the pH-sensitive dye BCECF injected via sharp recording microelectrodes into the neuron... | ['Animals', 'Cell Hypoxia', 'Cerebral Cortex', 'Fluoresceins', 'Fluorescent Dyes', 'Hydrogen-Ion Concentration', 'Hypoglycemia', 'In Vitro Techniques', 'Male', 'Membrane Potentials', 'Microelectrodes', 'Pyramidal Cells', 'Rats', 'Rats, Wistar', 'Time Factors'] | 9,631,445 | [['B01.050'], ['G03.197.300', 'G04.270.300'], ['A08.186.211.200.885.287.500'], ['D02.455.426.779.347', 'D03.633.300.953.275', 'D04.711.347'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['G02.300'], ['C18.452.394.984'], ['E05.481'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['E07.305.250.500'], ['A0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Simultaneous detection of esophageal and gastric carcinomas. | The case histories of six patients are presented where the diagnosis of carcinoma of the esophagus and the stomach was made at the same time by barium studies. The clinical history was elusive in two patients. In four of the six patients, histological proof of squamous carcinoma of the esophagus and adenocarcinoma of t... | ['Adenocarcinoma', 'Adult', 'Aged', 'Barium Sulfate', 'Carcinoma, Squamous Cell', 'Cardia', 'Esophageal Neoplasms', 'Esophagoscopy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasms, Multiple Primary', 'Pylorus', 'Radiography', 'Stomach Neoplasms'] | 7,549,729 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['D01.103.075', 'D01.875.800.800.850.075'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A03.556.875.875.163'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['E01.370.372.250.250.275', 'E01.370.3... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Gas chromatographic quantification of fatty acid methyl esters: flame ionization detection vs. electron impact mass spectrometry. | The determination of FAME by GC is among the most commonplace analyses in lipid research. Quantification of FAME by GC with FID has been effectively performed for some time, whereas detection with MS has been used chiefly for qualitative analysis of FAME. Nonetheless, the sensitivity and selectivity of MS methods advoc... | ['Calibration', 'Chromatography, Gas', 'Fatty Acids', 'Flame Ionization', 'Mass Spectrometry', 'Sensitivity and Specificity'] | 16,028,722 | [['E05.978.155'], ['E05.196.181.349'], ['D10.251'], ['E05.196.181.349.390'], ['E05.196.566'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Further study on the specificity of D-amino acid oxidase and D-aspartate oxidase and time course for complete oxidation of D-amino acids. | 1. D-Amino acid oxidase (D-AAO) oxidizes: D-Met, D-Pro, D-Phe, D-Tyr, D-Ile, D-Leu, D-Ala and D-Val. D-Ser, D-Arg, D-His, D-norleucine and D-Trp are oxidized at a low rate. D-Ornithine, cis-4-hydroxy-D-proline, D-Thr, D-Trp-methyl ester, N-acetyl-D-Ala and D-Lys are oxidized at a very low rate. 2. D-Asp, D-Glu and thei... | ['Amino Acid Oxidoreductases', 'Amino Acids', 'Animals', 'Cattle', 'D-Amino-Acid Oxidase', 'D-Aspartate Oxidase', 'Kinetics', 'Octopodiformes', 'Oxidation-Reduction', 'Substrate Specificity', 'Swine'] | 8,103,425 | [['D08.811.682.664.500'], ['D12.125'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D08.811.682.664.500.125'], ['D08.811.682.664.500.261'], ['G01.374.661', 'G02.111.490'], ['B01.050.500.644.116.600'], ['G02.700', 'G03.295.531'], ['G02.111.835'], ['B01.050.150.900.649.313.500.880']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The B subunit of Escherichia coli enterotoxin helps control the in vivo growth of solid tumors expressing the Epstein-Barr virus latent membrane protein 2A. | Latent membrane protein 2A (LMP2A) is expressed on almost all Epstein-Barr virus (EBV)-associated tumors and is a potential target for immunotherapeutic intervention and vaccination. However, LMP2A is not efficiently processed and presented on major histocompatibility antigens class I molecules to generate potent cytot... | ['Animals', 'Antineoplastic Agents', 'Bacterial Toxins', 'Cell Line, Tumor', 'Enterotoxins', 'Escherichia coli Proteins', 'Female', 'Immunization', 'Mice, Inbred BALB C', 'Neoplasms', 'T-Lymphocytes, Cytotoxic', 'Vaccinia virus', 'Viral Matrix Proteins'] | 25,641,882 | [['B01.050'], ['D27.505.954.248'], ['D23.946.123'], ['A11.251.210.190', 'A11.251.860.180'], ['D23.946.330'], ['D12.776.097.275'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Hydrogen peroxide regulates glucose-regulated protein 78 expression via a cyclooxygenase-2 dependent mechanism. | This study was designed to investigate the effect of hydrogen peroxide on the expression of endoplasmic reticulum stress marker glucose-regulated protein 78 (GRP78) in endothelial cells and reveals the possible role of cyclooxygenase in this effect. The porcine endothelial cell line was cultured in 1640 medium. Western... | ['Animals', 'Apoptosis', 'Arabidopsis Proteins', 'Aspirin', 'Blotting, Western', 'Caspase 12', 'Cell Line', 'Cell Survival', 'Cells, Cultured', 'Culture Media', 'Cyclooxygenase 2', 'Cyclooxygenase Inhibitors', 'Dose-Response Relationship, Drug', 'Endoplasmic Reticulum', 'Endothelial Cells', 'Endothelium, Vascular', 'Fl... | 20,665,602 | [['B01.050'], ['G04.146.954.035'], ['D12.776.765.149'], ['D02.455.426.559.389.657.410.595.176'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D08.811.277.656.262.500.126.550.920', 'D08.811.277.656.300.200.126.550.920', 'D12.644.360.075.405.550.920', 'D12.776.476... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of casual, ambulatory and self-measured blood pressure in a study of nitrendipine vs bisoprolol. | In a double-blind, placebo-controlled study the antihypertensive efficacy and tolerability of a single morning dose of either 10 mg bisoprolol (n = 26) or 20 mg nitrendipine (n = 27) were investigated. Blood pressure was measured by three techniques: (1) Casual blood pressure 24 h after the dose; (2) ambulatory 24-h wh... | ['Adrenergic beta-Antagonists', 'Adult', 'Aged', 'Bisoprolol', 'Blood Pressure Determination', 'Double-Blind Method', 'Female', 'Heart Rate', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Nitrendipine', 'Propanolamines', 'Self Care'] | 1,352,496 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116'], ['M01.060.116.100'], ['D02.033.100.624.698.085', 'D02.033.755.624.698.085', 'D02.092.063.624.698.085'], ['E01.370.370.140', 'E01.370.600.100'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E01.37... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Accuracy of pathologic interpretation of colorectal polyps by general pathologists in community practice. | BACKGROUND: The histologic features of colorectal polyps often guide colonoscopic surveillance and the need for surgical intervention. Our objective was to evaluate the pathologic interpretation of colorectal polyps by general pathologists in community practice.METHODS: Twenty histologic slides of colorectal polyps wer... | ['Adenocarcinoma', 'Adenoma', 'Biopsy', 'Colonic Neoplasms', 'Colonic Polyps', 'Colonoscopy', 'Diagnostic Errors', 'Hospitals, Community', 'Humans', 'Pathology, Clinical'] | 10,502,165 | [['C04.557.470.200.025'], ['C04.557.470.035'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Alginate-konjac glucomannan-chitosan beads as controlled release matrix. | Controlled release beads were prepared by using alginate (ALG), konjac glucomannan (KGM) and chitosan (CHI). Bovine serum albumin and insulin were used as model proteins for in vitro assessments. It was observed that KGM could be contained within beads, and faintness hydrogen binding and electrostatic interaction exist... | ['Administration, Oral', 'Alginates', 'Delayed-Action Preparations', 'Glucuronic Acid', 'Hexuronic Acids', 'Insulin', 'Mannans', 'Technology, Pharmaceutical'] | 12,204,571 | [['E02.319.267.100'], ['D09.698.068'], ['D26.255.210', 'E02.319.300.253'], ['D02.241.081.844.915.162.249', 'D02.241.152.811.162.500', 'D02.241.511.902.915.162.500', 'D09.811.922.162.500'], ['D02.241.081.844.915.400', 'D02.241.152.811.400', 'D02.241.511.902.915.400', 'D09.811.922.400'], ['D06.472.699.587.200.500.625', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A bio-inspired force control for cyclic manipulation of prosthetic hands. | The human hand is considered as the highest example of dexterous system capable of interacting with different objects and adapting its manipulation abilities to them. The control of poliarticulated prosthetic hands represents one important research challenge, typically aiming at replicating the manipulation capabilitie... | ['Hand', 'Humans', 'Prosthesis Design', 'Robotics'] | 26,737,373 | [['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.320.550', 'E07.695.680'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630']] | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
[Hidradenitis suppurativa]. | BACKGROUND: Hidradenitis suppurativa is an inflammatory, chronic and recurrent disease of appocrine glands, located in inguinal, axillar, perineal, perianal areas and scalp.OBJECTIVE: To determine the frequency and therapeutic management.METHODS: A retrospective, transverse, and descriptive study was carried out. All p... | ['Adult', 'Cross-Sectional Studies', 'Female', 'Hidradenitis Suppurativa', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies'] | 17,022,896 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C01.150.252.819.420', 'C01.800.720.420', 'C01.830.499', 'C17.800.838.765.420', 'C17.800.946.315.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
4-hexylresorcinol exerts antitumor effects via suppression of calcium oscillation and its antitumor effects are inhibited by calcium channel blockers. | The bacterial dormancy-inducing factor 4-hexylresorcinol (4-HR) has been shown to have synergistic antitumor effects when used in combination with cisplatin. In the present study, 4-HR was used as a single agent in the squamous carcinoma cell line SCC-9. The results demonstrated that 4-HR suppressed SCC-9 cell prolifer... | ['Animals', 'Annexin A5', 'Antineoplastic Agents', 'Apoptosis', 'Calcium Channel Blockers', 'Calcium Signaling', 'Carcinoma, Squamous Cell', 'Caspase 3', 'Cell Line, Tumor', 'Cell Proliferation', 'Fibroblasts', 'Gingiva', 'Hexylresorcinol', 'Humans', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Mouth Neoplasms... | 23,427,012 | [['B01.050'], ['D12.776.157.125.050.100'], ['D27.505.954.248'], ['G04.146.954.035'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Bayesian classifier for differentiating benign versus malignant thyroid nodules using sonographic features. | Thyroid nodules are a common, yet challenging clinical problem. The vast majority of these nodules are benign; however, deciding which nodule should undergo biopsy is difficult because the imaging appearance of benign and malignant thyroid nodules overlap. High resolution ultrasound is the primary imaging modality for ... | ['Adult', 'Aged', 'Artificial Intelligence', 'Bayes Theorem', 'Diagnosis, Differential', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Male', 'Middle Aged', 'Pattern Recognition, Automated', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Thyroid Neoplasms', 'Ultrasonography'] | 18,999,209 | [['M01.060.116'], ['M01.060.116.100'], ['G17.035.250', 'L01.224.050.375'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['M01.060.116.630'], ['L01.399.750'],... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Charge-density distribution in hydrogen methylphosphonates of calcium and lithium. | Two new crystal structures, calcium bis(hydrogen methylphosphonate), Ca(CH(3)PO(3)H)(2), and lithium hydrogen methylphosphonate, Li(CH(3)PO(3)H), have been obtained, and the experimental and theoretical charge densities, as well as their topological properties, are reported. Both compounds display layered structures. E... | ['Anions', 'Calcium', 'Cations', 'Crystallography, X-Ray', 'Hydrogen', 'Hydrogen Bonding', 'Lithium', 'Molecular Structure', 'Organophosphorus Compounds'] | 21,931,209 | [['D01.248.497.158'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D01.248.497.300'], ['E05.196.309.742.225'], ['D01.268.406', 'D01.362.340'], ['G02.282'], ['D01.268.549.450', 'D01.268.557.290', 'D01.552.528.480', 'D01.552.547.290'], ['G02.111.570', 'G02.466'], ['D02.705']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Attenuating social affective learning effects with Memory Suppression manipulations. | People can form opinions of other individuals based on information about their good or bad behavior. The present study investigated whether this affective learning might depend on memory links formed between initially neutral people and valenced information. First, participants viewed neutral faces paired with sentence... | ['Adolescent', 'Association Learning', 'Attitude', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Memory', 'Self Report', 'Social Behavior', 'Thinking', 'Young Adult'] | 26,799,984 | [['M01.060.057'], ['F02.463.425.069.296'], ['F01.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['E05.318.308.980.500', 'N05.715.360.300.800.500', 'N06.850.520.308.980.500'], ['F01.145.813'], ['F02.4... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Frequency doubling technology perimetry in open-angle glaucoma eyes with hemifield visual field damage: comparison of high-tension and normal-tension groups. | PURPOSE: To evaluate the performance of frequency doubling technology (FDT) perimetry in open-angle glaucoma eyes with hemifield visual field damage and to compare it between open-angle glaucoma with high pressure [high-tension glaucoma (HTG)] and those with normal pressure [normal-tension glaucoma (NTG)] groups.METHOD... | ['Cross-Sectional Studies', 'Female', 'Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Male', 'Middle Aged', 'Ocular Hypertension', 'Sensitivity and Specificity', 'Vision Disorders', 'Visual Field Tests', 'Visual Fields'] | 17,224,743 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['M01.060.116.630'], ['C11.525'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Quantitative analysis of goose and duck mixed down using visible/NIR spectroscopy]. | Goose down and duck down have very similar appearance but the quality of goose down is better than that of duck down in general. There is a highest allowable limit as specified by the various national standards of feather and down for the percentage of duck feather or down mixed in goose feather or down. Traditional de... | ['Algorithms', 'Animals', 'Ducks', 'Feathers', 'Geese', 'Linear Models', 'Models, Theoretical', 'Spectroscopy, Near-Infrared'] | 22,715,765 | [['G17.035', 'L01.224.050'], ['B01.050'], ['B01.050.150.900.248.050.200', 'B01.050.150.900.248.690.345'], ['A13.370'], ['B01.050.150.900.248.050.350', 'B01.050.150.900.248.690.492'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Identification of down-regulated expressed sequence tag at chromosome 3p21 in nasopharyngeal carcinoma]. | BACKGROUND & OBJECTIVE: It was reported that a locus of high frequency loss of heterozygosity was found at 3p14-25 of nasopharyngeal carcinoma (NPC) cells. This study was designed to identify the expressed sequence tags (ESTs) associated with NPC at chromosome 3p21 in order to clone new candidate NPC-associated genes a... | ['Carcinoma, Squamous Cell', 'Cell Line, Tumor', 'Chromosomes, Human, Pair 3', 'Down-Regulation', 'Expressed Sequence Tags', 'Gene Expression Regulation, Neoplastic', 'Genes, Tumor Suppressor', 'Humans', 'Loss of Heterozygosity', 'Nasopharyngeal Neoplasms', 'Nasopharynx', 'Reverse Transcriptase Polymerase Chain Reactio... | 12,561,426 | [['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.187.520.300.235.250', 'G05.360.162.520.300.235.250'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G05.360.340.024.340.137.275'], ['G05.308.370'], ['G05.360.340.024.340.375.249', 'G05.360.340.024.340.415.400'], ['... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Heavy metal levels in feathers of wild turkeys from Virginia. | Levels of lead, cadmium, nickel, and zinc were determined in feathers of 175 wild turkeys (Meleagris gallopava) shot by hunters in 19 Virginia counties in 2 physiographic regions. Lead and nickel levels did not vary by county, region, sex, or age. Zinc and cadmium levels were significantly (P less than 0.01) higher in ... | ['Age Factors', 'Animals', 'Cadmium', 'Feathers', 'Female', 'Lead', 'Male', 'Metals', 'Nickel', 'Sex Factors', 'Turkeys', 'Virginia', 'Zinc'] | 444,755 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ability of four different techniques of measuring bone mass to diagnose vertebral fractures in postmenopausal women. | Since bone mass has been shown to be an important determining factor of fractures in vitro, we undertook a study to evaluate whether bone mass measurements could separate postmenopausal women with vertebral compression fractures from women of a similar age without fractures. We also wanted to see if methods of measurin... | ['Adult', 'Aged', 'Aged, 80 and over', 'Bone and Bones', 'Female', 'Fractures, Bone', 'Humans', 'Menopause', 'Methods', 'Middle Aged', 'Spinal Injuries'] | 3,455,166 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A02.835.232', 'A10.165.265'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.157.500', 'G08.686.841.249.500'], ['E05.581'], ['M01.060.116.630'], ['C26.117.500']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Androgen deprivation therapy sensitizes prostate cancer cells to T-cell killing through androgen receptor dependent modulation of the apoptotic pathway. | Despite recent advances in diagnosis and management, prostrate cancer remains the second most common cause of death from cancer in American men, after lung cancer. Failure of chemotherapies and hormone-deprivation therapies is the major cause of death in patients with castration-resistant prostate cancer (CRPC). Curren... | ['Androgen Antagonists', 'Androstenes', 'Animals', 'Apoptosis', 'Cell Line, Tumor', 'Disease Progression', 'Humans', 'Immunomodulation', 'Immunotherapy', 'Male', 'Mice', 'Neuronal Apoptosis-Inhibitory Protein', 'Phenylthiohydantoin', 'Prostate', 'Prostatic Neoplasms, Castration-Resistant', 'RNA Interference', 'RNA, Sma... | 25,344,864 | [['D06.347.065', 'D27.505.696.399.450.065'], ['D04.210.500.054.079'], ['B01.050'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465', 'G12.535'], ['E02.095.465.425'], ['B01.050.150.900.649.313.992.635.505.500'], ['D08.811.46... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Treatment of cancer of the breast with Patey's modified radical mastectomy]. | Patey's operation was used to treat breast cancer in 658 cases between 1956 and 1976 at the Bologna University Surgical Clinic. Follow-up in 562 cases revealed 5-yr and 10-yr survival rates substantially similar to those obtained by Halsted and others. It is felt that the type of operation used is of relative importanc... | ['Breast Neoplasms', 'Female', 'Humans', 'Mastectomy', 'Prognosis'] | 460,613 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of human blood for volatile N-nitrosamines by gas chromatography-chemiluminescence detection. | A method was developed to separate and measure trace levels of volatile N-nitrosamines (NAs) in human blood that either eliminated or accounted for in vitro artifactual formation of N-nitrosodimethylamine (NDMA) through the use of water blanks, added inhibitor (ascorbic acid) and added morpholine. The absolute minimum ... | ['Adult', 'Chromatography, Gas', 'Dimethylnitrosamine', 'Female', 'Humans', 'Indicators and Reagents', 'Luminescent Measurements', 'Male', 'Nitrosamines', 'Photolysis', 'Spectrophotometry, Ultraviolet'] | 3,711,226 | [['M01.060.116'], ['E05.196.181.349'], ['D02.654.442.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.410'], ['E05.196.712.516'], ['D02.654.442'], ['G02.740.685'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of aurothioglucose and auranofin on radiographic progression in rheumatoid arthritis. | Radiographic films of 40 patients participating in a single centre patient blind study of auranofin versus aurothioglucose were evaluated in a random order by one reader. The two treatment groups were comparable with respect to number of erosions and total radiographic score at the start of the study. Only in the auran... | ['Adult', 'Aged', 'Arthritis, Rheumatoid', 'Auranofin', 'Aurothioglucose', 'Clinical Trials as Topic', 'Drug Administration Schedule', 'Female', 'Gold', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Random Allocation', 'Time Factors'] | 3,096,626 | [['M01.060.116'], ['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D02.691.675.249.150'], ['D02.691.675.249'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E02.319.283'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['B01.050.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Unread Second-Opinion Radiology Reports: A Potential Waste of Health Care Resources. | OBJECTIVE. The purpose of this study was to investigate how frequently second-opinion radiology reports are not read by clinicians and to identify reasons why reports are not read. MATERIALS AND METHODS. This retrospective study included 4696 consecutive second-opinion reports of external imaging examinations that were... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Logistic Models', 'Male', 'Middle Aged', "Practice Patterns, Physicians'", 'Radiography', 'Referral and Consultation', 'Reproducibility of Results', 'Retrospective Studies', 'Ultrasonograp... | 32,783,557 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Subarachnoid space of the CNS, nasal mucosa, and lymphatic system. | We have briefly reviewed the literature pertaining to the movement of tracer molecules and infectious organisms within the olfactory nerve. There is a body of evidence indicating that tracers placed in the CSF will quickly move via the olfactory nerve to the nasal mucosa and then to the cervical lymph nodes. Organic an... | ['Animals', 'Axonal Transport', 'Cerebrospinal Fluid', 'Cisterna Magna', 'Coloring Agents', 'Ethmoid Bone', 'Gold Colloid, Radioactive', 'Haplorhini', 'Humans', 'Lymphatic System', 'Mice', 'Nasal Mucosa', 'Olfactory Bulb', 'Olfactory Nerve', 'Olfactory Pathways', 'Rabbits', 'Subarachnoid Space', 'Time Factors', 'Virus ... | 85,446 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Influence of Tablet Formulation, Drug Concentration, and pH Modification on the Stability of Extemporaneously Compounded Levothyroxine Suspensions. | Three brands of levothyroxine tablets are currently available in New Zealand (Eltroxin, Mercury Pharma, Synthroid) for extemporaneous compounding into suspensions. This study aims to determine whether tablet brand (i.e., formulation), concentration, storage conditions, as well as pH, impact the stability of compounded ... | ['Chromatography, High Pressure Liquid', 'Drug Compounding', 'Drug Stability', 'Hydrogen-Ion Concentration', 'Suspensions', 'Tablets', 'Temperature', 'Thyroxine'] | 29,877,863 | [['E05.196.181.400.300'], ['E05.916.270'], ['E05.916.330'], ['G02.300'], ['D20.280.810', 'D26.255.165.810'], ['D26.255.830'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['D06.472.931.812', 'D12.125.072.050.767']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of long-term oral testosterone undecanoate therapy on urinary symptoms: data from a 1-year, placebo-controlled, dose-ranging trial in aging men with symptomatic hypogonadism. | BACKGROUND: There has been a longstanding question as to whether testosterone therapy could precipitate or worsen urinary symptoms in aging men. We investigated the effects of 1-year oral testosterone undecanoate (TU) therapy on urinary symptoms in aging, hypogonadal men.METHODS: A total of 322 men ?50 years with sympt... | ['Administration, Oral', 'Aged', 'Aging', 'Androgens', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Humans', 'Hypogonadism', 'Lower Urinary Tract Symptoms', 'Male', 'Middle Aged', 'Prostatic Hyperplasia', 'Testosterone'] | 26,030,346 | [['E02.319.267.100'], ['M01.060.116.100'], ['G07.345.124'], ['D27.505.696.399.472.161'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.391.482'], ['C23.888.942.343'], ['M01.060.116.630'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Results of transplanting regions of the midbrain of human embryos into the brain of adult rats]. | A principle possibility for transplantation of the midbrain areas of the human embryos into the brain of mature rats has been demonstrated. For successful xeno-transplantations the midbrain of 7-8-week-old embryos is the most suitable. The intracerebral transplants grow predominantly along the capsule of the white subs... | ['Animals', 'Cell Differentiation', 'Gestational Age', 'Humans', 'Mesencephalon', 'Nerve Tissue', 'Rats'] | 3,190,466 | [['B01.050'], ['G04.152'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.186.211.132.659'], ['A10.755'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The binding of drugs to plasma proteins and the interpretation of measurements of plasma concentrations of drugs in patients with poor renal function. | The intensity of a drug's action is related to its concentration in plasma water. Since the analytical methods for determining concentrations of drugs in plasma measure this as well as the drug bound to plasma proteins, evaluation of the binding of drugs to plasma proteins is needed for proper interpretation of drug le... | ['Acute Kidney Injury', 'Binding, Competitive', 'Blood Proteins', 'Dose-Response Relationship, Drug', 'Humans', 'Kidney Failure, Chronic', 'Pharmaceutical Preparations', 'Protein Binding'] | 851,114 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D12.776.124'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['D26'], ['G02.111.679', 'G03.808']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Release of carrot plasma membrane-associated phosphatidylinositol kinase by phospholipase A2 and activation by a 70 kDa protein. | Plasma membranes were isolated from carrot (Daucus carota L.) cells grown in suspension culture and treated with phospholipase A2 from snake or bee venom for 10 min. As a result of this treatment, phosphatidylinositol kinase activity was recovered in the soluble fraction. There was no detectable diacylglycerol kinase o... | ['1-Phosphatidylinositol 4-Kinase', 'Cell Membrane', 'Cells, Cultured', 'Enzyme Activation', 'In Vitro Techniques', 'Membrane Lipids', 'Molecular Weight', 'Phosphatidylcholines', 'Phospholipases A', 'Phospholipases A2', 'Phosphotransferases', 'Plant Proteins', 'Vegetables'] | 1,311,960 | [['D08.811.913.696.620.550'], ['A11.284.149'], ['A11.251'], ['G02.111.263', 'G03.328'], ['E05.481'], ['D10.570'], ['G02.494'], ['D10.570.755.375.760.400.800'], ['D08.811.277.352.100.680.750'], ['D08.811.277.352.100.680.750.937'], ['D08.811.913.696'], ['D12.776.765'], ['B01.650.160.956', 'B01.650.510.956', 'G07.203.300.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A chronic hypoxic response in photoreceptors alters the vitreous proteome in mice. | Reduced oxygenation of the outer retina in the aging eye may activate a chronic hypoxic response in RPE and photoreceptor cells and is considered as a risk factor for the development of age-related macular degeneration (AMD). In mice, a chronically active hypoxic response in the retinal pigment epithelium (RPE) or phot... | ['Animals', 'Chronic Disease', 'Disease Models, Animal', 'Electroretinography', 'Eye Proteins', 'GTP-Binding Proteins', 'Gene Expression Regulation', 'Hypoxia', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'Mice', 'Mice, Inbred C57BL', 'Photoreceptor Cells, Vertebrate', 'Proteome', 'RNA, Messenger', 'Real-Time Polymera... | 31,181,196 | [['B01.050'], ['C23.550.291.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E01.370.380.225', 'E01.370.405.270'], ['D12.776.306'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['G05.308'], ['C23.888.852.079'], ['D12.776.260.103.625.750', 'D12.776.930.125.625.750'], ['B01.050.150.900.649.313.992.635.505.500']... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Local changes in bone marrow at MRI after treatment of extremity soft tissue sarcoma. | OBJECTIVE: To determine the prevalence and appearance of magnetic resonance imaging (MRI) signal changes that occur in local bone marrow after radiation therapy (RT) and/or chemotherapy for extremity soft tissue sarcoma (STS).MATERIALS AND METHODS: Seventy patients with primary STS at the level of a long bone who also ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Bone Marrow', 'Combined Modality Therapy', 'Contrast Media', 'Disease Progression', 'Extremities', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Retrospective Studies', 'Sarcoma', 'Soft Tissue Neoplasms'] | 18,704,399 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A15.382.216'], ['E02.186'], ['D27.505.259.500', 'D27.720.259'], ['C23.550.291.656'], ['A01.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.7... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hyperglycemia reduces the extent of cerebral infarction in rats. | Although hyperglycemia is known to exacerbate neuronal injury in the setting of reversible brain ischemia, its effect on irreversible thrombotic infarction is less well understood. In this study, unilateral thrombotic infarction was induced photochemically in the parietal cortex of Wistar rats. Seven days later, brains... | ['Animals', 'Blood Glucose', 'Brain', 'Cerebral Infarction', 'Glucose', 'Hyperglycemia', 'Male', 'Mannitol', 'Rats', 'Rats, Inbred Strains'] | 3,109,078 | [['B01.050'], ['D09.947.875.359.448.500'], ['A08.186.211'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['D09.947.875.359.448'], ['C18.452.394.952'], ['D02.033.800.609', 'D09.853.609'], ['B01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Upregulation of mineralocorticoid- and glucocorticoid-receptor gene expression by Sp-I. | The mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) belong to the steroid/thyroid hormone superfamily of ligand-induced transcription factors. Both activate the human Na/K ATPase alpha1 and beta1 genes transcriptionally. To assess the role of the transcription factor Sp1 and the nuclear factor I (NF-I)... | ['Animals', 'CCAAT-Enhancer-Binding Proteins', 'COS Cells', 'Cell Line', 'DNA-Binding Proteins', 'Humans', 'NFI Transcription Factors', 'Nuclear Proteins', 'Promoter Regions, Genetic', 'Receptors, Glucocorticoid', 'Receptors, Mineralocorticoid', 'Sodium-Potassium-Exchanging ATPase', 'Sp1 Transcription Factor', 'Transcr... | 10,329,476 | [['B01.050'], ['D12.776.260.108.124', 'D12.776.660.167', 'D12.776.930.127.124'], ['A11.251.210.172.500', 'A11.329.228.220'], ['A11.251.210'], ['D12.776.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.260.605', 'D12.776.930.612'], ['D12.776.660'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fungal arthritis of the wrist caused by Candida parapsilosis during infliximab therapy for rheumatoid arthritis. | A 60-year-old woman with rheumatoid arthritis, who had been treated with infliximab, presented with uncontrollable wrist arthritis. Fungal arthritis caused by Candida parapsilosis was confirmed by examining her aspirated joint fluid. Her infliximab therapy was interrupted, and antifungal therapy with fluconazole was st... | ['Antibodies, Monoclonal', 'Antifungal Agents', 'Antirheumatic Agents', 'Arthritis, Infectious', 'Arthritis, Rheumatoid', 'Candida', 'Candidiasis', 'Debridement', 'Female', 'Fluconazole', 'Humans', 'Infliximab', 'Middle Aged', 'Wrist Joint'] | 22,350,574 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D27.505.954.122.136'], ['D27.505.954.329'], ['C01.100', 'C05.550.114.099'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['C01.150.703... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity. | A(1) adenosine receptor (AR) agonists display antiischemic and antiepileptic neuroprotective activity, but peripheral cardiovascular side effects impeded their development. SAR study of N(6)-cycloalkylmethyl 4'-truncated (N)-methanocarba-adenosines identified 10 (MRS5474, N(6)-dicyclopropylmethyl, K(i) = 47.9 nM) as a ... | ['Animals', 'Anticonvulsants', 'CHO Cells', 'Cricetinae', 'Cricetulus', 'Humans', 'Male', 'Mice', 'Molecular Docking Simulation', 'Nucleosides', 'Protein Conformation', 'Receptor, Adenosine A1', 'Structure-Activity Relationship'] | 22,921,089 | [['B01.050'], ['D27.505.954.427.080'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.595.249', 'L01.224.160.249'], ['D09.408.595', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A universal PCR primer to detect members of the Potyviridae and its use to examine the taxonomic status of several members of the family. | A universal primer (Sprimer: 5'-GGX AAY AAY AGY GGX CAZ CC-3', X = A, G, C or T; Y = T or C; Z = A or G), designed from the consensus sequences that code for the conserved sequence GNNSGQP in the NIb region of members of the family Potyviridae, was used to amplify by RT-PCR the 3'-terminal genome regions from infected ... | ['Apiaceae', 'Avena', 'China', 'Consensus Sequence', 'Garlic', 'Mosaic Viruses', 'Phylogeny', 'Plant Diseases', 'Plants, Medicinal', 'Potyviridae', 'Potyvirus', 'RNA', 'RNA, Viral', 'Reverse Transcriptase Polymerase Chain Reaction', 'Zea mays'] | 11,402,861 | [['B01.650.940.800.575.912.250.075'], ['B01.650.940.800.575.912.250.822.060'], ['Z01.252.474.164'], ['G02.111.570.580.175'], ['B01.650.940.800.575.912.250.618.100.050.060.300'], ['B04.715.464'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G15.610'], ['B01.650.560'], ['B04.715.635', 'B04.820.578.782'], ['B04.715.464.60... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
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