Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Effect of sub-inhibitory concentrations of antibiotics on adhesion of Campylobacter jejuni in vitro. | The effects of sub-inhibitory concentrations (MIC 50 and MIC 25) of clindamycin, erythromycin and chloramphenicol on the adherence of Campylobacter jejuni to INT 407 cells were studied. The results indicated that the adhesion was inhibited at various extents, mostly by MIC 50, and that the inhibition increased with tim... | ['Analysis of Variance', 'Anti-Bacterial Agents', 'Bacterial Adhesion', 'Campylobacter fetus', 'Cells, Cultured', 'Chloramphenicol', 'Clindamycin', 'Epithelial Cells', 'Erythromycin', 'Humans', 'Microbial Sensitivity Tests'] | 3,663,336 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D27.505.954.122.085'], ['G06.099.050'], ['B03.440.180.325', 'B03.660.150.235.250.500.220'], ['A11.251'], ['D02.033.455.706.300', 'D02.455.426.559.389.565.175', 'D02.640.529.175'], ['D03.383.773.532.500.125', 'D09.408.471.500.125'], ['A11.436'], ['D02... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Heat debt as an index for cold adaptation in men. | Several types of cold adaptation in men have been described in the literature (metabolic, insulative, hypothermic). The aim of this study is to show that the decrease of heat debt can be considered as a new index for cold adaptation. Ten male subjects were acclimated by water immersions (temperature 10-15 degrees C, 4 ... | ['Acclimatization', 'Adult', 'Body Temperature', 'Cold Temperature', 'Hot Temperature', 'Humans', 'Male', 'Time Factors'] | 3,597,234 | [['G07.025.133', 'G16.012.500.133'], ['M01.060.116'], ['E01.370.600.875.374', 'G07.110'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.10... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Re-evaluate the Efficacy and Safety of Human Urinary Kallidinogenase (RESK): Protocol for an Open-Label, Single-Arm, Multicenter Phase IV Trial for the Treatment of Acute Ischemic Stroke in Chinese Patients. | Acute ischemic stroke (AIS) is a major medical challenge in China. Thrombolytic drugs recommended for the treatment of AIS usually have a narrow time window. Human urinary kallidinogenase (HUK) was approved by the China Food and Drug Administration (CFDA) in 2005 for the treatment of mild to moderate AIS, and it is thu... | ['Administration, Intravenous', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Brain Ischemia', 'China', 'Clinical Protocols', 'Female', 'Fibrinolytic Agents', 'Follow-Up Studies', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Severity of Illness Index', 'Stroke', 'Tissue Kallikreins', 'Tomograp... | 28,265,861 | [['E02.319.267.082'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300.150', 'C14.907.253.092'], ['Z01.252.474.164'], ['E02.183', 'N05.715.360.330.125'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['E05.318.372.500.750.249', 'N05.715.360.330.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The role of intramembrane Ca2+ in the hydrolysis of the phospholipids of Escherichia coli by Ca2+-dependent phospholipases. | Ca2+-dependent phospholipases A require Ca2+ concentrations in the millimolar range for optimal activity toward artificial substrates. Because Ca2+-dependent phospholipases A2 degrade the phospholipids of Escherichia coli, treated with the membrane-active antibiotic polymixin B equally well with and without added Ca2+ ... | ['Calcium', 'Cell Membrane', 'Egtazic Acid', 'Escherichia coli', 'Hydrolysis', 'Lipopolysaccharides', 'Membrane Lipids', 'Phospholipases', 'Phospholipases A', 'Phospholipases A1', 'Phospholipases A2', 'Phospholipids', 'Polymyxin B'] | 3,918,043 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.284.149'], ['D02.092.782.258.368.257', 'D02.241.081.018.269'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G02.380'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['D10.570'], ['D08.811.277.352.10... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
EphrinB2 reverse signaling protects against capillary rarefaction and fibrosis after kidney injury. | Microvascular disease, a characteristic of acute and chronic kidney diseases, leads to rarefaction of peritubular capillaries (PTCs), promoting secondary ischemic injury, which may be central to disease progression. Bidirectional signaling by EphB4 receptor and ephrinB2 ligand is critical for angiogenesis during murine... | ['Acute Kidney Injury', 'Animals', 'Capillaries', 'Cells, Cultured', 'Ephrin-B2', 'Fibrosis', 'Kidney', 'Mice', 'Mice, Inbred C57BL', 'Neovascularization, Physiologic', 'Receptor, EphB4', 'Signal Transduction'] | 23,492,730 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['B01.050'], ['A07.015.461.165'], ['A11.251'], ['D12.644.276.500.700', 'D12.776.467.500.700', 'D12.776.543.287.700', 'D23.529.500.700'], ['C23.550.355'], ['A05.810.453'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.64... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
"Sporadic" dystrophic epidermolysis bullosa: a new dominant or mitis recessive mutation? | We describe a case of dystrophic epidermolysis bullosa which occurred in a young boy who presented thickened and dystrophic nails both in hands and feet, atrophic scars on the elbows and knees, some large bullae and milia on the hands and ankles. The parents were clinically unaffected and the family medical history was... | ['Adolescent', 'Collagen', 'Diagnosis, Differential', 'Epidermolysis Bullosa Dystrophica', 'Genes, Dominant', 'Genes, Recessive', 'Humans', 'Immunohistochemistry', 'Male', 'Mutation', 'Skin'] | 10,980,463 | [['M01.060.057'], ['D05.750.078.280', 'D12.776.860.300.250'], ['E01.171'], ['C16.131.831.493.160', 'C16.320.850.275.160', 'C17.300.200.367', 'C17.800.804.493.160', 'C17.800.827.275.160', 'C17.800.865.410.160'], ['G05.360.340.024.340.240', 'G05.420.320'], ['G05.360.340.024.340.415', 'G05.420.325'], ['B01.050.150.900.649... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Successful treatment with an unrelated-donor bone marrow transplant in an HLA-deficient patient with severe combined immune deficiency ("bare lymphocyte syndrome"). | An 8-month-old white female infant with Pneumocystis carinii pneumonia had a normal blastogenic response to mitogens but no response to a variety of antigens, as well as a poor response to allogeneic cells in one-way mixed lymphocyte culture assays. The patient's mononuclear cells had defective class I (HLA-A, -B, -C) ... | ['Bone Marrow Transplantation', 'Female', 'HLA Antigens', 'Humans', 'Immunologic Deficiency Syndromes', 'Infant', 'Tissue Donors'] | 2,299,498 | [['E02.095.147.725.040', 'E04.936.580.040'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.673'], ['M01.060.703'], ['M01.898']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Impact of Yersinia pseudotuberculosis on the in vitro production of cytokines by whole blood cells of donors]. | The impact of two plasmid (47, 82 MD), single plasmid (47 MD) and non plasmid Y. pseudotuberculosis strains, Y. enterocolitica (47 MD) as well as Y. pseudotuberculosis superantigen (YPM) on the production of interleukin-1 (IL-1), interleukin-6 (IL-6), interferon-alpha (IFN = alpha) and tumor necrosis factor alpha (TNF-... | ['Adolescent', 'Bacterial Proteins', 'Blood Cells', 'Blood Donors', 'Cells, Cultured', 'Cytokines', 'Humans', 'Immunoenzyme Techniques', 'Interferon-alpha', 'Interleukin-1', 'Interleukin-6', 'Lipopolysaccharides', 'Molecular Weight', 'Plasmids', 'Superantigens', 'Tumor Necrosis Factor-alpha', 'Yersinia pseudotuberculos... | 12,449,699 | [['M01.060.057'], ['D12.776.097'], ['A11.118', 'A15.145.229'], ['M01.898.313'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['D12.644.276.374.440.890.250', 'D12.776.467.374.440.890.250', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Assessing mutant huntingtin fragment and polyglutamine aggregation by atomic force microscopy. | Huntington disease (HD), a neurodegenerative disorder, is caused by an expansion of more than 35-40 polyglutamine (polyQ) repeats located near the N-terminus of the huntingtin (htt) protein. The expansion of the polyQ domain results in the ordered assembly of htt fragments into fibrillar aggregates that are the main co... | ['Amino Acid Sequence', 'Humans', 'Huntingtin Protein', 'Huntington Disease', 'Image Processing, Computer-Assisted', 'Microscopy, Atomic Force', 'Molecular Sequence Data', 'Nerve Tissue Proteins', 'Nuclear Proteins', 'Protein Multimerization', 'Protein Structure, Tertiary', 'Recombinant Fusion Proteins', 'Time-Lapse Im... | 21,187,152 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.441'], ['C10.228.140.079.545', 'C10.228.140.380.278', 'C10.228.662.262.249.750', 'C10.574.500.497', 'C16.320.400.430', 'F03.615.250.400', 'F03.615.400.390'], ['L01.224.308'], ['E01.370.350.515.666.400', 'E05.595.666.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Colorimetric study of dental porcelain. The characteristics of the absorption and scattering coefficients]. | Recently, the demand for a more natural and harmonious color of porcelain-fused-to-metal restoration is on the increase due to the recent rise in esthetic values among the patients. However, the usual methodology of shade taking, color transmission, and color evaluation is not so precise. We have thus tried to resolve ... | ['Color', 'Colorimetry', 'Dental Porcelain', 'Esthetics, Dental', 'Metal Ceramic Alloys', 'Spectrophotometry'] | 2,135,319 | [['G01.590.540.199'], ['E05.196.922.250'], ['D25.339.376', 'J01.637.051.339.376', 'J01.637.153.377'], ['E06.420'], ['D01.552.033.690', 'D25.058.520', 'D25.339.208.720', 'J01.637.051.058.520', 'J01.637.051.339.208.720'], ['E05.196.712.726', 'E05.196.867.826']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Synthetic precursors for TCNQF4(2-) compounds: synthesis, characterization, and electrochemical studies of (Pr4N)2TCNQF4 and Li2TCNQF4. | Careful control of the reaction stoichiometry and conditions enables the synthesis of both LiTCNQF(4) and Li(2)TCNQF(4) to be achieved. Reaction of LiI with TCNQF(4), in a 4:1 molar ratio, in boiling acetonitrile yields Li(2)TCNQF(4). However, deviation from this ratio or the reaction temperature gives either LiTCNQF(4... | ['Crystallography, X-Ray', 'Electrochemistry', 'Lithium Compounds', 'Magnetic Resonance Spectroscopy', 'Molecular Structure', 'Quaternary Ammonium Compounds', 'Technetium Compounds'] | 23,153,174 | [['E05.196.309.742.225'], ['H01.181.529.307'], ['D01.510'], ['E05.196.867.519'], ['G02.111.570', 'G02.466'], ['D01.625.062.500', 'D02.092.877', 'D02.675.276'], ['D01.925']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Black TiO2 | At present, transmembrane glycoprotein CD133 highly expressed pancreatic cancer stem cells (PCSCs), with the features of chemotherapeutic/radiotherapeutic resistance and exclusive tumorigenic potential, are considered as the primary cause of metastasis and recurrence in pancreatic cancer, and therefore are an effective... | ['AC133 Antigen', 'Cell Proliferation', 'Cell Survival', 'Dose-Response Relationship, Drug', 'Fluorescent Dyes', 'Humans', 'Magnetic Resonance Imaging', 'Nanostructures', 'Optical Imaging', 'Pancreatic Neoplasms', 'Particle Size', 'Phototherapy', 'Structure-Activity Relationship', 'Surface Properties', 'Titanium', 'Tum... | 29,947,365 | [['D12.776.395.550.007', 'D12.776.543.550.023'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['J01.637.512'], ['E01.370.350.589', 'E05.642'], ['C04.5... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effectiveness and cost of selective decontamination of the digestive tract in critically ill intubated patients. A randomized, double-blind, placebo-controlled, multicenter trial. | We evaluated the effect of selective decontamination of the digestive tract (SDD) on the incidence of ventilator-associated pneumonia (VAP) and its associated morbidity and cost in a mixed population of intubated patients. Two hundred seventy-one consecutive patients admitted to the intensive care units (ICUs) of five ... | ['Bacteria', 'Bacterial Infections', 'Cause of Death', 'Ceftriaxone', 'Cephalosporins', 'Colony Count, Microbial', 'Confidence Intervals', 'Critical Care', 'Critical Illness', 'Digestive System', 'Double-Blind Method', 'Drug Therapy, Combination', 'Female', 'Gram-Negative Bacteria', 'Gram-Positive Bacteria', 'Health Ca... | 9,731,025 | [['B03'], ['C01.150.252'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['D02.065.589.099.249.190.190.155', 'D02.886.665.074.190.190.155', 'D03.633.100.300.249.190.190.155'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.300.249'], ['E01.370... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
In vitro screening procedure for characterization of thrombogenic properties of plasma treated surfaces. | Estimation of thrombogenic surface properties is an important aspect of hemocompatibility studies. To improve our understanding of interaction between blood and biomaterial surfaces, there is a need to employ standardized methods that are both effective and efficient. This contribution details a systematic approach for... | ['Blood Coagulation', 'Blood Platelets', 'Coated Materials, Biocompatible', 'Humans', 'Mass Screening', 'Materials Testing', 'Microscopy, Confocal', 'Microscopy, Electron, Scanning', 'Surface Properties', 'Toxicology'] | 27,154,919 | [['G09.188.390.150'], ['A11.118.188', 'A15.145.229.188'], ['D25.130.420', 'J01.637.051.130.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.780.500'], ['E05.570'], ['E01.370.35... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Fabrication of two-layered channel system with embedded electrodes to measure resistance across epithelial and endothelial barriers. | This manuscript describes a straightforward fabrication process for embedding Ag/AgCl electrodes within a two-layer poly(dimethylsiloxane) (PDMS) microfluidic chip where an upper and a lower channel are separated by a semiporous membrane. This system allows for the reliable real-time measurement of transendothelial and... | ['Animals', 'Cell Line', 'Dimethylpolysiloxanes', 'Electric Impedance', 'Electrochemistry', 'Electrodes', 'Endothelium', 'Epithelial Cells', 'Equipment Design', 'Membranes, Artificial', 'Microfluidic Analytical Techniques'] | 20,178,370 | [['B01.050'], ['A11.251.210'], ['D02.756.650.700.150', 'D05.750.900.850.150', 'D25.720.900.850.150', 'J01.637.051.720.900.850.150'], ['G01.358.500.249.277.350'], ['H01.181.529.307'], ['E07.305.250'], ['A10.272.491'], ['A11.436'], ['E05.320'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['E05.588.465']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Nitric oxide-mediated inactivation of mammalian ferrochelatase in vivo and in vitro: possible involvement of the iron-sulphur cluster of the enzyme. | To investigate the role of the iron-sulphur cluster in mammalian ferrochelatases, the terminal enzyme of the haem biosynthetic pathway, we examined the interaction of nitric oxide (NO) and ferrochelatase. When macrophage cell line RAW 264.7 cells were treated with interferon-gamma and lipopolysaccharide NO synthesis in... | ['Amino Acid Oxidoreductases', 'Animals', 'Arginine', 'Cell Line', 'Cloning, Molecular', 'Enzyme Inhibitors', 'Escherichia coli', 'Ferrochelatase', 'Humans', 'Immunoblotting', 'Interferon-gamma', 'Iron-Sulfur Proteins', 'Lipopolysaccharides', 'Macrophages', 'Mammals', 'Mice', 'Molsidomine', 'Nitric Oxide', 'Nitric Oxid... | 7,544,575 | [['D08.811.682.664.500'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['A11.251.210'], ['E05.393.220'], ['D27.505.519.389'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D08.811.520.500', 'D12.776.157.427.374.375.957', 'D12.776.556.579.374.375.617', 'D12.776.575.562'], ['B01.050... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Phlaeothrips-lineage of fungus feeding thrips (Thysanoptera: Phlaeothripidae) in Iran with a new species of Hindsiothrips. | Hindsiothrips sisakhti sp. n. is described from leaf litter in Iran, this being the first record of the genus from this country. A key is provided to the seven Phlaeothripinae genera recorded from Iran that are considered members of the Phlaeothrips-lineage, in which most species are fungus feeding: Aleurodothrips, Hin... | ['Animals', 'Female', 'Iran', 'Male', 'Thysanoptera'] | 24,613,875 | [['B01.050'], ['Z01.252.245.500.350'], ['B01.050.500.131.617.800']] | ['Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Does the use of a free internal mammary artery graft on the left anterior descending artery compromise long-term survival? | OBJECTIVES: The aim of the study was to determine if there is a long-term outcomes disadvantage associated with using the internal mammary artery (IMA) as a free graft to the left anterior descending artery (LAD) during coronary artery bypass graft surgery.METHODS: Between 1991 and 2014, 21 876 consecutive patients und... | ['Aged', 'Cohort Studies', 'Coronary Angiography', 'Coronary Artery Bypass', 'Coronary Artery Disease', 'Coronary Vessels', 'Databases, Factual', 'Female', 'Follow-Up Studies', 'Graft Rejection', 'Graft Survival', 'Humans', 'Internal Mammary-Coronary Artery Anastomosis', 'Logistic Models', 'Male', 'Middle Aged', 'Odds ... | 28,481,987 | [['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Molecular characterization of 21 X-ALD Portuguese families: identification of eight novel mutations in the ABCD1 gene. | X-linked adrenoleukodystrophy (X-ALD) is the most common inherited peroxisomal disorder. The gene associated with X-ALD, ABCD1, encodes a peroxisomal ATP-binding cassette half-transporter. In this study, we describe the molecular characterization of 21 affected Portuguese families. The complete coding region of the ABC... | ['ATP Binding Cassette Transporter, Subfamily D, Member 1', 'ATP-Binding Cassette Transporters', 'Adrenoleukodystrophy', 'Electrophoresis, Polyacrylamide Gel', 'Fatty Acids', 'Female', 'Fibroblasts', 'Humans', 'Male', 'Mutation', 'Polymerase Chain Reaction', 'Portugal'] | 12,175,782 | [['D12.776.157.530.100.209.500', 'D12.776.395.550.020.419.500', 'D12.776.543.550.192.419.500', 'D12.776.543.585.100.209.500'], ['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['C10.228.140.163.100.084', 'C10.228.140.163.100.362.250', 'C10.228.140.695.625.250', 'C10.314.400.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Late sciatic nerve palsy caused by hematoma after primary total hip arthroplasty. | A case of late sciatic nerve palsy caused by subfascial hematoma after uncemented right total hip arthroplasty is reported. The patient developed respiratory distress 13 days postoperatively and was admitted to another institution, where she was diagnosed with pulmonary embolism and was subsequently therapeutically ant... | ['Aged', 'Arthroplasty, Replacement, Hip', 'Female', 'Hematoma', 'Humans', 'Sciatic Neuropathy'] | 15,343,542 | [['M01.060.116.100'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['C23.550.414.838'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.668.829.500.675']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Late renal function following whole abdominal irradiation. | Sixty patients treated with whole abdominal radiotherapy who had remained disease-free since completion of treatment participated in a study to assess the late clinical and biochemical effects of bilateral renal irradiation. Minimum follow-up was 5 years with a maximum of 20 years and a median of 9 years. Fifty-two pat... | ['Female', 'Follow-Up Studies', 'Gastrointestinal Neoplasms', 'Humans', 'Kidney', 'Kidney Function Tests', 'Lymphoma, Non-Hodgkin', 'Male', 'Middle Aged', 'Ovarian Neoplasms', 'Radiation Injuries', 'Radiation Protection', 'Radiotherapy Dosage', 'Time Factors'] | 8,693,108 | [['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['E01.370.390.400'], ['C04.557.386.480', 'C15.604.515.569.480', 'C20.683.515.761.480'], ['M01.060.116.630'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Occult hypoglycemia in a diabetic patient on peritoneal dialysis. | In a patient with diabetes mellitus undergoing icodextrin continuous ambulatory peritoneal dialysis, the interference caused by icodextrin metabolites in bedside glucose analyzers led to an overestimation of capillary glucose levels and the potential for inappropriate therapy. We report this case to raise an awareness ... | ['Aged', 'Blood Glucose', 'Diabetes Mellitus, Type 2', 'Glucans', 'Glucose', 'Humans', 'Hypoglycemia', 'Icodextrin', 'Insulin', 'Kidney Failure, Chronic', 'Male', 'Peritoneal Dialysis'] | 16,276,267 | [['M01.060.116.100'], ['D09.947.875.359.448.500'], ['C18.452.394.750.149', 'C19.246.300'], ['D05.750.078.562', 'D09.698.365'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.984'], ['D05.750.078.562.622', 'D09.698.365.399'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Electron microscopic and histochemical characteristics of hepatomas arising during long-term administration of carbon tetrachloride]. | Hepatomas arising as a result of prolonged injection of CCl4 consist of cells in which the processes of dystrophy and intracellular regeneration are pronounced to a different degree. In the late stages of development, hepatomas tend to malignancy, exhibiting cells that bear ultrastructural resemblance to the cells of m... | ['Animals', 'Carbon Tetrachloride Poisoning', 'Collagen', 'Endoplasmic Reticulum', 'Liver Glycogen', 'Liver Neoplasms, Experimental', 'Mice', 'Microscopy, Electron', 'Oxidoreductases', 'Ribonucleoproteins'] | 7,397,369 | [['B01.050'], ['C25.723.177'], ['D05.750.078.280', 'D12.776.860.300.250'], ['A11.284.430.214.190.875.248'], ['D05.750.078.562.388.518', 'D09.698.365.388.518'], ['C04.588.274.623.460', 'C04.619.540', 'C06.301.623.460', 'C06.552.697.580', 'E05.598.500.496.750'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[First experience with intravenous thrombolysis in ischemic stroke in Serbia]. | INTRODUCTION: Systemic thrombolytic therapy in the first three hours of acute ischemic stroke (IS) significantly improves its outcome. This therapy was approved for treatment in USA in 1997, and in most European countries in 2002. First intravenous thrombolysis of 15 in Serbia was carried out in February 2006.OBJECTIVE... | ['Adolescent', 'Adult', 'Female', 'Fibrinolytic Agents', 'Humans', 'Injections, Intravenous', 'Male', 'Middle Aged', 'Plasminogen Activators', 'Stroke', 'Thrombolytic Therapy'] | 18,368,901 | [['M01.060.057'], ['M01.060.116'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['M01.060.116.630'], ['D08.811.277.656.300.760.635', 'D08.811.277.656.959.350.635', 'D12.776.124.125.662'], ['C10.228... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Family medicine and family therapy: comparative development, methods, and roles. | Family medicine and family therapy have evolved separately, but the fields are now increasingly in contact with each other. Today's family physician needs a deeper grasp of their similarities and differences. This paper compares the two disciplines in terms of their (1) membership criteria for treatment, (2) considered... | ['Behavior Therapy', 'Family Practice', 'Family Therapy', 'Humans'] | 6,833,966 | [['F04.754.137'], ['H02.403.340.500'], ['F04.754.864.581.273'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Iatrogenic Exserohilum infection of the central nervous system: mycological identification and histopathological findings. | An outbreak of fungal infections has been identified in patients who received epidural injections of methylprednisolone acetate that was contaminated with environmental molds. In this report, we present the mycological and histopathological findings in an index case of Exserohilum meningitis and vasculitis in an immuno... | ['Ascomycota', 'Brain', 'Humans', 'Injections, Epidural', 'Meningitis, Fungal', 'Spinal Cord'] | 23,222,492 | [['B01.300.107'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.580.300'], ['C01.150.703.181.500', 'C01.207.198.500', 'C10.228.228.198.500', 'C10.228.614.300'], ['A08.186.854']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dual sexual and drug-related predictors of hepatitis C incidence among sex workers in a Canadian setting: gaps and opportunities for scale-up of hepatitis C virus prevention, treatment, and care. | BACKGROUND: Hepatitis C virus (HCV) represents a significant cause of morbidity and mortality globally. While sex workers may face elevated HCV risks through both drug and sexual pathways, incidence data among sex workers are severely lacking. HCV incidence and predictors of HCV seroconversion among women sex workers i... | ['Adult', 'Canada', 'Directive Counseling', 'Female', 'Hepacivirus', 'Hepatitis C', 'Humans', 'Incidence', 'Male', 'Prevalence', 'Proportional Hazards Models', 'Risk Factors', 'Sex Workers', 'Sexual Behavior', 'Sexually Transmitted Diseases', 'Socioeconomic Factors', 'Substance Abuse, Intravenous', 'Transgender Persons... | 28,027,990 | [['M01.060.116'], ['Z01.107.567.176'], ['F02.784.176.279', 'F04.408.413.349', 'N02.421.461.363.349'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.59... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Lipophosphoglycan of Leishmania major that vaccinates against cutaneous leishmaniasis contains an alkylglycerophosphoinositol lipid anchor. | The major cell surface glycoconjugate of Leishmania major, a putative parasite receptor for macrophages, is a lipophosphoglycan containing 81.6% (wt/wt) carbohydrate, 17.0% (wt/wt) phosphate, and 1.4% (wt/wt) lipid. It has been purified to homogeneity by hydrophobic chromatography and consists of a polydisperse family ... | ['Animals', 'Antigens, Protozoan', 'Glycoconjugates', 'Glycolipids', 'Leishmania tropica', 'Leishmaniasis', 'Mice', 'Phosphatidylinositols', 'Phospholipid Ethers', 'Vaccination', 'Vaccines'] | 3,480,520 | [['B01.050'], ['D23.050.293'], ['D09.400'], ['D09.400.410', 'D10.390'], ['B01.268.475.868.488.680'], ['C01.610.752.300.500', 'C01.610.858.560', 'C01.920.813', 'C17.800.838.775.560'], ['B01.050.150.900.649.313.992.635.505.500'], ['D10.570.755.375.760.400.942'], ['D02.033.800.875.875.750', 'D02.355.460.750', 'D10.570.755... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Oxybutynin, desmopressin and enuresis. | PURPOSE: A review of the scarce literature concerning oxybutynin treatment for nocturnal enuresis reveals that its success is greatest when enuresis is combined with daytime incontinence. The renal and bladder related characteristics of children with monosymptomatic enuresis responsive to oxybutynin were evaluated.MATE... | ['Child', 'Cholinergic Antagonists', 'Deamino Arginine Vasopressin', 'Enuresis', 'Female', 'Humans', 'Male', 'Mandelic Acids', 'Renal Agents'] | 11,696,812 | [['M01.060.406'], ['D27.505.519.625.120.200', 'D27.505.696.577.120.200'], ['D06.472.699.631.692.781.100.250', 'D12.644.400.900.100.250', 'D12.644.456.925.100.250', 'D12.644.548.691.692.781.100.250', 'D12.776.631.650.937.100.250'], ['C12.777.934.284', 'C13.351.968.934.252', 'F01.145.126.856', 'F03.388.400'], ['B01.050.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of brainstem involvement in multiple sclerosis. | BACKGROUND/AIMS: the aim of the present study was to determine the optimum method to detect brainstem lesions in patients with Multiple Sclerosis (MS).METHODS: 72 patients with the diagnosis of relapsing-remitting MS were prospectively included. brainstem functional system score (bSfS) (part of the expanded disability ... | ['Acoustic Stimulation', 'Adolescent', 'Adult', 'Brain Stem', 'Evoked Potentials, Auditory', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Multiple Sclerosis', 'Prospective Studies', 'Young Adult'] | 24,718,819 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.057'], ['M01.060.116'], ['A08.186.211.132'], ['G07.265.216.500.370', 'G07.888.250', 'G11.561.200.500.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Vectorial measurement of blood velocity by means of ultrasound. | The complete determination of blood velocity as a vector can be achieved using ultrasound techniques, by correlating the echo signals provided by a sector transducer. Here the general problem is approached by suggesting the processing procedure which should be adopted, so that longitudinal and transverse velocity compo... | ['Blood Flow Velocity', 'Electronics, Medical', 'Humans', 'Rheology', 'Transducers', 'Ultrasonics'] | 1,453,788 | [['E01.370.370.130', 'G09.330.380.630.080'], ['H01.671.293.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.830', 'H01.671.808'], ['E07.305.812'], ['H01.671.031.849']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Ectopic Schistosoma mansoni Eggs Inside a Lipoma. | Ectopic schistosomiasis is uncommon and tends to occur when the parasite's eggs or adult forms are located far from their normal site. This report presents the first described case of ectopic Schistosoma mansoni eggs inside a subcutaneous lipoma far from the tissues of this worm's life cycle and with no connection to e... | ['Adult', 'Animals', 'Humans', 'Lipoma', 'Male', 'Ovum', 'Oxamniquine', 'Schistosoma mansoni', 'Schistosomiasis mansoni', 'Schistosomicides'] | 26,598,562 | [['M01.060.116'], ['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.550.400'], ['A05.360.490.690', 'A11.497.497', 'A16.690'], ['D03.633.100.810.350.600', 'D03.633.100.810.470.600'], ['B01.050.500.500.736.715.770.680.700'], ['C01.610.335.865.859.576', 'C01.920.922.576'], ['D27.505.954.122.250.0... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of Self-Selected Exercise on Strength in Charcot-Marie-Tooth Disease Subtypes. | BACKGROUND: Preliminary studies have supported the utility of exercise as a treatment for Charcot-Marie-Tooth disease (CMT) patients. Despite being the most common inherited neuropathy, there remains a paucity of guidelines for CMT management.METHODS: A retrospective chart review was performed on 297 CMT patients. Self... | ['Adult', 'Charcot-Marie-Tooth Disease', 'Exercise', 'Exercise Therapy', 'Female', 'Hand Strength', 'Humans', 'Male', 'Retrospective Studies'] | 28,669,366 | [['M01.060.116'], ['C10.500.300.200', 'C10.574.500.495.200', 'C10.668.829.800.300.200', 'C16.131.666.300.200', 'C16.320.400.375.200'], ['G11.427.410.698.277', 'I03.350'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['E01.370.600.425.500', 'G11.427.560.500'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Elevated CD147 expression is associated with shorter overall survival in non-small cell lung cancer. | A number of studies have reported on the prognostic role of CD147 expression in non-small cell lung cancer (NSCLC); however, the results remain controversial. This study aims to investigate the impact of CD147 on the prognosis of NSCLC by means of a meta-analysis. A literature search was performed for relevant studies ... | ['Adult', 'Aged', 'Basigin', 'Carcinoma, Non-Small-Cell Lung', 'Humans', 'Lung Neoplasms', 'Middle Aged', 'Prognosis', 'Survival Analysis'] | 28,445,149 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.395.550.045', 'D12.776.543.550.187', 'D23.050.285.040'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dexmedetomidine Attenuates Lipopolysaccharide Induced MCP-1 Expression in Primary Astrocyte. | Background. Neuroinflammation which presents as a possible mechanism of delirium is associated with MCP-1, an important proinflammatory factor which is expressed on astrocytes. It is known that dexmedetomidine (DEX) possesses potent anti-inflammatory properties. This study aimed to investigate the potential effects of ... | ['Animals', 'Astrocytes', 'Cells, Cultured', 'Chemokine CCL2', 'Dexmedetomidine', 'Gene Expression Regulation', 'Glial Fibrillary Acidic Protein', 'Lipopolysaccharides', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Adrenergic, alpha-2'] | 28,286,770 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['A11.251'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['D03.383.129.308.245'], ['G05.308'], ['D05.750.078.593.400', 'D12.776.220.475.400'], ['D09.400.500', 'D... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phosphorus removal performance and biological dephosphorization process in treating reclaimed water by Integrated Vertical-flow Constructed Wetlands (IVCWs). | Phosphorous removal in adsorption had been extensively researched; however, the biological dephosphorization process and optimum operating parameters have not been discussed or quantified in Integrated Vertical-flow Constructed Wetlands (IVCWs). In this study, IVCWs planted with different plants were employed to evalua... | ['Phosphorus', 'Waste Disposal, Fluid', 'Waste Water', 'Water', 'Water Purification', 'Wetlands'] | 28,666,149 | [['D01.268.666'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D20.944.932', 'N06.850.460.710.865'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900'], ['G16.500.275.157.812', 'N06.230.124.625']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Development of a monoclonal antibody-based immunochromatographic assay for the detection of carbamazepine and carbamazepine-10, 11-epoxide. | In this study, haptens were designed to produce highly sensitive and specific monoclonal antibodies (mAb) against carbamazepine (CBZ) and its metabolite carbamazepine-10, 11-epoxide (CBZ-EP). According to the results of our competitive enzyme-linked immunosorbent assay (ic-ELISA), the half-maximum inhibitory concentrat... | ['Antibodies, Immobilized', 'Antibodies, Monoclonal', 'Carbamazepine', 'Chromatography, Liquid', 'Humans', 'Immunoassay', 'Limit of Detection', 'Linear Models'] | 32,109,745 | [['D12.776.124.486.485.114.207', 'D12.776.124.790.651.114.207', 'D12.776.377.715.548.114.207', 'D12.776.463.250'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D03.633.300.240.127'], ['E05.196.181.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566',... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Modeling nikkomycin Z dosing and pharmacology in murine pulmonary coccidioidomycosis preparatory to phase 2 clinical trials. | Nikkomycin Z (NikZ) is a chitin synthase inhibitor with activity against Coccidioides species that is being developed as a first-in-class orphan product for treatment of coccidioidomycosis. It has previously been shown to reduce lethal respiratory infections in mice to undetectable levels when treatment is begun 48 hou... | ['Aminoglycosides', 'Animals', 'Antifungal Agents', 'Coccidioidomycosis', 'Disease Models, Animal', 'Dogs', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Mice', 'Nonlinear Dynamics'] | 24,421,256 | [['D09.408.051'], ['B01.050'], ['D27.505.954.122.136'], ['C01.150.703.203'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.850', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Empyema thoracis: a review of a 4 1/2 year experience of cases requiring surgical treatment. | During the period January 1985 to June 1989, 53 cases of empyema thoracis were treated surgically at Papworth hospital regional cardio-thoracic centre. Of these, 47 patients underwent thoracotomy and decortication as their primary surgical treatment. The remaining six patients were treated by rib resection. Prior to su... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Drainage', 'Empyema', 'Female', 'Humans', 'Male', 'Methods', 'Middle Aged', 'Postoperative Complications'] | 2,371,438 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['E02.309', 'E04.237'], ['C01.830.305', 'C23.550.470.756.305'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['M01.060.116.630'], ['C23.550.767']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Proximal flow convergence region as assessed by real-time 3-dimensional echocardiography: challenging the hemispheric assumption. | OBJECTIVE: Traditionally, a hemispheric assumption for the proximal flow convergence region (PFCR) is used when calculating mitral regurgitant (MR) effective orifice area (EROA). However, 2-dimensional (2D) echocardiography limits evaluation of the complete PFCR contour. Real-time 3-dimensional (3D) echocardiography (R... | ['Aged', 'Echocardiography, Doppler', 'Echocardiography, Three-Dimensional', 'Female', 'Humans', 'Male', 'Mitral Valve', 'Mitral Valve Insufficiency', 'Myocardial Contraction', 'Observer Variation', 'Reproducibility of Results', 'Severity of Illness Index'] | 17,400,118 | [['M01.060.116.100'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['E01.370.350.130.750.230', 'E01.370.350.400.200', 'E01.370.350.850.220.230', 'E01.370.370.380.220.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.541.510.507'], ['C14.280.48... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Novel somatostatin analogs with tyrosine kinase inhibitory and antitumor activity. | A series of new somatostatin analogs have been developed and tested for antitumor activity. Some analogs strongly inhibited tyrosine kinase activity of human colon tumor cells and this activity correlated well with their antiproliferative effect, but did not correlate with GH release inhibition. The best analogs strong... | ['Amino Acid Sequence', 'Animals', 'Antineoplastic Agents', 'Cell Division', 'Growth Hormone', 'Growth Hormone-Releasing Hormone', 'Humans', 'Lung Neoplasms', 'Mice', 'Molecular Sequence Data', 'Neoplasm Metastasis', 'Protein-Tyrosine Kinases', 'Somatostatin', 'Structure-Activity Relationship', 'Tumor Cells, Cultured'] | 8,096,383 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D27.505.954.248'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['D06.472.699.327.740.860', 'D12.644.400.400.740.860', 'D12.644.548.365.740.860', 'D12.776.631.650.405.740.860'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Peripheral neuroectodermal tumor of the chest wall in a 19-year-old female. | A small cell round tumor involving the chest wall of a 19-year-old female had features that by light microscopy were considered consistent with Ewing's tumor. At the ultrastructural level the cells contained small quantities of glycogen and had irregular dendritic processes with rare dense core granules and microtubule... | ['Adult', 'Carcinoma, Small Cell', 'Female', 'Humans', 'Lung Neoplasms', 'Neoplasm Metastasis', 'Peritoneal Neoplasms'] | 2,544,053 | [['M01.060.116'], ['C04.557.470.200.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.697.650', 'C23.550.727.650'], ['C04.588.033.513', 'C04.588.274.780', 'C06.301.780', 'C06.844.620']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Older women's lives through time. | This 6-year longitudinal study of 103 community-dwelling older women examined changes in physical and mental health and self conceptions and the relationships among self conceptions, physical health, and depression. Over time, physical health, personal growth, and purpose in life declined; depression increased; and pos... | ['Adaptation, Physiological', 'Adaptation, Psychological', 'Aged', 'Aged, 80 and over', 'Aging', 'Depression', 'Female', 'Humans', 'Longitudinal Studies', 'Middle Aged', 'Self Concept', "Women's Health"] | 9,504,209 | [['G07.025', 'G16.012.500'], ['F01.058'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['M01.060.116.630'], ['F01.752.747.792'], ['N01.400.90... | ['Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type plasminogen activator in murine model of embolic stroke. | BACKGROUND AND PURPOSE: Remote ischemic conditioning is cardioprotective in myocardial infarction and neuroprotective in mechanical occlusion models of stroke. However, there is no report on its therapeutic potential in a physiologically relevant embolic stroke model (embolic middle cerebral artery occlusion) in combin... | ['Administration, Intravenous', 'Animals', 'Brain', 'Combined Modality Therapy', 'Fibrinolytic Agents', 'Infarction, Middle Cerebral Artery', 'Ischemic Preconditioning', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Models, Animal', 'Phosphorylation', 'Proto-Oncogene Proteins c-akt', 'Regional Blood Flow', 'Stroke', 'Thrombol... | 22,910,893 | [['E02.319.267.082'], ['B01.050'], ['A08.186.211'], ['E02.186'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['C10.228.140.300.150.477.200.450', 'C10.228.140.300.510.200.387', 'C10.228.140.300.775.200.200.450', 'C14.907.253.092.477.200.450', 'C14.907.253.560.200.387', 'C14.907.253.855.200.200... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Regenerative Potential of the Product "CardioCell" Derived from the Wharton's Jelly Mesenchymal Stem Cells for Treating Hindlimb Ischemia. | In recent years, mesenchymal stem cells (MSCs) have emerged as a promising therapeutic modality in regenerative medicine. They hold great promise for treating civilization-wide diseases, including cardiovascular diseases, such as acute myocardial infarction and critical limb ischemia. MSCs isolated from Wharton's jelly... | ['Animals', 'Cells, Cultured', 'Disease Models, Animal', 'Hindlimb', 'Humans', 'Ischemia', 'Male', 'Mesenchymal Stem Cell Transplantation', 'Mesenchymal Stem Cells', 'Mice', 'Mice, SCID', 'Neovascularization, Physiologic', 'Regeneration', 'Wharton Jelly'] | 31,540,534 | [['B01.050'], ['A11.251'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A13.473'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.513'], ['E02.095.147.500.500.625', 'E04.936.225.687.625'], ['A11.329.830.500', 'A11.872.590.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An antibacterial metabolite from Lasiodiplodia pseudotheobromae F2. | In searching for symbionts derived from bioactive natural products, six sulfureous diketopiperazines designated as lasiodiplines A-F (1-6) were characterized from the culture of Lasiodiplodia pseudotheobromae F2, previously residing in the apparently normal flower of Illigera rhodantha (Hernandiaceae). Identification o... | ['Anti-Bacterial Agents', 'Ascomycota', 'Bacteria', 'Diketopiperazines', 'Microbial Sensitivity Tests', 'Models, Molecular', 'Molecular Conformation'] | 24,529,576 | [['D27.505.954.122.085'], ['B01.300.107'], ['B03'], ['D03.383.606.385'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['E05.599.595'], ['G02.111.570.820']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pulmonary hypertension and pregnancy: the experience of a tertiary institution over 15 years. | BACKGROUND: Pulmonary hypertension (PH) in pregnancy is associated with a high maternal mortality and morbidity and has been found to be as high as 30-56%.AIM: To review the management of such patients in a tertiary center over a 15 year period, as the current literature consists of a few case reports, a few small case... | ['Adult', 'Age Factors', 'Apgar Score', 'Delivery, Obstetric', 'Female', 'Humans', 'Hypertension, Pulmonary', 'Infant, Newborn', 'Monitoring, Physiologic', 'Pregnancy', 'Pregnancy Complications', 'Pregnancy Outcome', 'Severity of Illness Index', 'Tertiary Care Centers'] | 25,849,682 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.600.050'], ['E04.520.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['M01.060.703.520'], ['E01.370.520'], ['G08.686.784.769'], ['C13.703'], ['E01.789.700', 'G08.686.784.769.496'], ['E05.318.308.980.438.475.4... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The occurrence of the 15;17 translocation in acute promyelocytic leukemia. | For many years, acute promyelocytic leukemia (APL) has been associated with the 15;17 translocation. However, questions concerning an eventual geographic distribution have been raised by the Second and Fourth International Workshops on Chromosomes in Leukemia. Using a statistical approach, we showed that, even if the t... | ['Chromosomes, Human, 13-15', 'Chromosomes, Human, 16-18', 'Humans', 'Karyotyping', 'Leukemia, Myeloid, Acute', 'Oncogenes', 'Specimen Handling', 'Translocation, Genetic'] | 3,455,847 | [['A11.284.187.520.300.370', 'G05.360.162.520.300.370'], ['A11.284.187.520.300.415', 'G05.360.162.520.300.415'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['C04.557.337.539.275'], ['G05.360.340.024.340.375.500'], ['E01.370.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intracellular fate of phase I Coxiella burnetii in guniea pig peritoneal macrophages. | Cultivated guinea pig peritoneal macrophages were infected with radio-labeled phase I Coxiella burnetii in order to assess the intracellular distribution of ingested rickettsiae. Localization of organisms was determined by fractionation of macrophage homogenates by equilibrium density centrifugation on sucrose gradient... | ['Animals', 'Ascitic Fluid', 'Coxsackievirus Infections', 'Enterovirus', 'Guinea Pigs', 'Lysosomes', 'Macrophages', 'Male', 'Phagocytosis', 'Polyethylene Glycols'] | 6,842,464 | [['B01.050'], ['A12.207.119'], ['C01.925.782.687.359.213'], ['B04.820.578.750.284'], ['B01.050.150.900.649.313.992.550'], ['A11.284.430.214.190.875.190.550'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['G04.417.350', 'G09.188.665', 'G12.450.564.809', 'G12.688'], ['D02.033.455.... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Celioclysis in the treatment of purulent peritonitis]. | The advantages and contraindications associated with peritoneal drainage are discussed. Reference is made to the advantages of drainage combined with continuous coelioclysis in accordance with a personal method, using doxicycline diluted in saline passed into the peritoneal cavity via a small catheter. A personal serie... | ['Doxycycline', 'Drainage', 'Humans', 'Peritoneal Cavity', 'Peritonitis', 'Therapeutic Irrigation'] | 692,891 | [['D02.455.426.559.847.562.900.200', 'D04.615.562.900.200'], ['E02.309', 'E04.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.923.047.025.600.678'], ['C01.463.600', 'C06.844.640'], ['E02.779.492.500', 'E02.831.535.492.500', 'E05.927']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of genetic alterations on chromosome 17 and loss of hormone receptors in breast cancer. | To investigate possible relationships between genetic alterations and hormonal deregulation during breast cancer development and/or progression, we examined 616 primary breast cancers for loss of heterozygosity (LOH) at chromosomal regions 16q24, 17p13.3 and 17q21, and for amplifications of the ERBB2 and c-MYC loci. A ... | ['Breast Neoplasms', 'Chromosomes, Human, Pair 16', 'Chromosomes, Human, Pair 17', 'DNA, Neoplasm', 'Gene Amplification', 'Gene Deletion', 'Genes, erbB-2', 'Genes, myc', 'Heterozygote', 'Humans', 'Neoplasms, Hormone-Dependent', 'Receptors, Estrogen', 'Receptors, Progesterone'] | 7,880,720 | [['C04.588.180', 'C17.800.090.500'], ['A11.284.187.520.300.415.420', 'G05.360.162.520.300.415.420'], ['A11.284.187.520.300.415.425', 'G05.360.162.520.300.415.425'], ['D13.444.308.425'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.360.340.024.340.375.500.791.295.3... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neonatal lupus: a case report. | An infant boy born to an asymptomatic mother was found to have typical cutaneous and serologic findings of the neonatal lupus syndrome. Anti-Ro and anti-La antibodies were detected in both the mother and the child. Evaluation of the maternal grandmother who had been diagnosed with "lupus" was nondiagnostic. | ['Adult', 'Antibodies, Antinuclear', 'Female', 'Humans', 'Infant', 'Lupus Erythematosus, Discoid', 'Male', 'Skin'] | 6,607,821 | [['M01.060.116'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C17.300.475.479', 'C17.800.480.479'], ['A17.815']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Intracellular delivery of universal proteins using a lysine headgroup containing cationic liposomes: deciphering the uptake mechanism. | An amino acid-based cationic lipid having a TFA counterion (trifluoroacetic acid counterion) in the lysine headgroup was used to deliver functional proteins into human cervical cancer cells, HeLa, in the presence of serum. Proteins used in the study were fluorescein isothiocyanate (FITC) labeled bovine serum albumin, m... | ['Animals', 'Cations', 'Cattle', 'Drug Delivery Systems', 'Electrophoresis, Polyacrylamide Gel', 'Endocytosis', 'Flow Cytometry', 'HeLa Cells', 'Humans', 'Liposomes', 'Lysine', 'Mice', 'Microscopy, Confocal', 'Serum Albumin, Bovine'] | 24,224,643 | [['B01.050'], ['D01.248.497.300'], ['B01.050.150.900.649.313.500.380.271'], ['E02.319.300'], ['E05.196.401.402', 'E05.301.300.319'], ['G04.417'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['A... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Identification of the type II Na(+)-Pi cotransporter (Npt2) in the osteoclast and the skeletal phenotype of Npt2-/- mice. | We previously reported that a type II sodium phosphate (Na(+)-Pi) cotransporter (Npt2) protein is expressed in osteoclasts and that Pi limitation decreases osteoclast-mediated bone resorption in vitro. We also demonstrated that mice homozygous for the disrupted Npt2 gene (Npt2-/-) exhibit a unique age-dependent bone ph... | ['Animals', 'Bone Resorption', 'Cells, Cultured', 'Cloning, Molecular', 'DNA, Complementary', 'Female', 'Gene Expression', 'Homeostasis', 'Hypophosphatemia', 'Kidney Tubules, Proximal', 'Macrophages', 'Male', 'Mice', 'Mice, Knockout', 'Osteoclasts', 'Phenotype', 'Phosphates', 'RNA, Messenger', 'Rabbits', 'Sodium-Phosph... | 11,704,500 | [['B01.050'], ['C05.116.264', 'G11.427.213.150'], ['A11.251'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G05.297'], ['G07.410'], ['C18.452.750.400'], ['A05.810.453.736.560.570'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of a vigorous walking program on body composition, and carbohydrate and lipid metabolism of obese young men. | With no attempt made to influence their diet, six sedentary obese men ages 19 to 31 completed 16 weeks of vigorous walking 90 min, 5 days/week, on a treadmill at up to 3.2 mph on a 10% grade, expending about 1100 kcal per session. Body composition studies indicated a loss of 5.9 kg of body fat and a gain of 0.2 kg of l... | ['Adipose Tissue', 'Adult', 'Blood Glucose', 'Energy Intake', 'Humans', 'Insulin', 'Lipids', 'Male', 'Muscles', 'Obesity', 'Physical Exertion', 'Skinfold Thickness'] | 474,467 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunohistochemical detection of human telomerase reverse transcriptase (hTERT) and c-kit in serous ovarian carcinoma: a clinicopathologic study. | OBJECTIVE: This study investigated the expression of human telomerase reverse transcriptase (hTERT) and c-kit in a cohort of serous ovarian carcinomas by immunohistochemistry with regard to outcome and clinicopathologic variables.METHODS: Formalin-fixed, paraffin-embedded archival tissue sections of 10 benign serous cy... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Cell Growth Processes', 'Cystadenocarcinoma, Serous', 'DNA-Binding Proteins', 'Female', 'Humans', 'Immunohistochemistry', 'Middle Aged', 'Mitosis', 'Neoplasm Staging', 'Ovarian Neoplasms', 'Prognosis', 'Proto-Oncogene Proteins c-kit', 'Survival Rate', 'Telome... | 16,005,054 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['G04.161', 'G07.345.249.410'], ['C04.557.470.200.025.480.240', 'C04.557.470.590.480.240'], ['D12.776.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
X-linked adrenal hypoplasia congenita is caused by abnormal nuclear localization of the DAX-1 protein. | Mutations in the DAX-1 [dosage-sensitive sex reversal-adrenal hypoplasia congenita (AHC) critical region on the X chromosome; NR0B1] gene cause X-linked AHC associated with hypogonadotropic hypogonadism. DAX-1 encodes an unusual orphan member of the nuclear hormone receptor superfamily, acting as a transcriptional repr... | ['Adrenal Insufficiency', 'Animals', 'COS Cells', 'Cell Nucleus', 'Chlorocebus aethiops', 'DAX-1 Orphan Nuclear Receptor', 'DNA-Binding Proteins', 'Gene Deletion', 'Gene Expression Regulation', 'HeLa Cells', 'Humans', 'Polymerase Chain Reaction', 'Receptors, Retinoic Acid', 'Repressor Proteins', 'Transcription Factors'... | 12,034,880 | [['C19.053.500'], ['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['D12.776.826.209.059', 'D12.776.930.780.625.186'], ['D12.776.260'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.308'], ['A11.251.... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Different sized somatic NF1 locus rearrangements in neurofibromatosis 1-associated malignant peripheral nerve sheath tumors. | Neurofibromatosis type 1 (NF1) patients are at increased risk of developing both benign (neurofibromas) and malignant (malignant peripheral nerve sheath tumors, MPNST) tumors. Molecular data on tumor progression are scarce, and few studies have compared the NF1 locus copy number in these two tumor types. To further exp... | ['Chromosome Aberrations', 'Chromosomes, Human, Pair 17', 'DNA Mutational Analysis', 'Gene Rearrangement', 'Humans', 'Nerve Sheath Neoplasms', 'Neurofibromatosis 1'] | 20,686,819 | [['C23.550.210', 'G05.365.590.175'], ['A11.284.187.520.300.415.425', 'G05.360.162.520.300.415.425'], ['E05.393.760.700.300'], ['G05.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.580.600', 'C10.551.775.500', 'C10.668.829.725.500'], ['C04.557.580.600.580.590.650', 'C04.700.631.650', 'C10.562.600.500',... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Estrogen-related receptor ã controls sterol regulatory element-binding protein-1c expression and alcoholic fatty liver. | Although SREBP-1c regulates key enzymes required for hepatic de novo lipogenesis, the mechanisms underlying transcriptional regulation of SREBP-1c in pathogenesis of alcoholic fatty liver is still incompletely understood. In this study, we investigated the role of ERRã in alcohol-mediated hepatic lipogenesis and examin... | ['Animals', 'Cells, Cultured', 'Fatty Liver, Alcoholic', 'Hep G2 Cells', 'Humans', 'Male', 'Mice, Inbred C57BL', 'Receptors, Estrogen', 'Sterol Regulatory Element Binding Protein 1', 'Transcriptional Activation', 'Up-Regulation'] | 31,479,733 | [['B01.050'], ['A11.251'], ['C06.552.241.390', 'C06.552.645.390', 'C25.775.100.087.645.390'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D12.776.826.750.350', 'D12.776.930.778.350'], [... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Definition of the concordis species group of the genus Euseius (Acari: Phytoseiidae), with a morphological reassessment of the species included. | Phytoseiidae (Acari) is the best known family of predatory mites. Within this family, Euseius Wainstein is one of the largest genera. The species of this genus have generalist feeding behavior, including in their diet mites and pollen. Some studies have demonstrated the potential of certain Euseius species to control p... | ['Animal Distribution', 'Animal Structures', 'Animals', 'Body Size', 'Female', 'Male', 'Mites', 'Organ Size'] | 26,624,744 | [['F01.145.113.069', 'G16.049'], ['A13'], ['B01.050'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['B01.050.500.131.166.132.419'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Annexin A2 is regulated by ovarian cancer-peritoneal cell interactions and promotes metastasis. | Our recent research identified the protein annexin A2 to be regulated by ovarian cancer-peritoneal cell interactions. This study investigated the role of annexin A2 in ovarian cancer metastasis and its potential utility as a novel therapeutic target, using in vitro and in vivo ovarian cancer models. Annexin A2 expressi... | ['Animals', 'Annexin A2', 'Antibodies, Neutralizing', 'Cell Communication', 'Cell Line, Tumor', 'Chick Embryo', 'Coculture Techniques', 'Cystadenocarcinoma, Serous', 'Female', 'Humans', 'Immunohistochemistry', 'Mice', 'Mice, Nude', 'Neoplasm Metastasis', 'Ovarian Neoplasms', 'RNA, Small Interfering', 'Xenograft Model A... | 23,945,256 | [['B01.050'], ['D12.776.157.125.050.060'], ['D12.776.124.486.485.114.244', 'D12.776.124.790.651.114.244', 'D12.776.377.715.548.114.244'], ['G04.085'], ['A11.251.210.190', 'A11.251.860.180'], ['A13.350.150', 'A16.331.200'], ['E05.481.500.374'], ['C04.557.470.200.025.480.240', 'C04.557.470.590.480.240'], ['B01.050.150.90... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterisation and distribution of calcitonin gene-related peptide in a primitive teleost, the eel, Anguilla anguilla and comparison with calcitonin. | Radioimmunoassay (RIA), radioreceptor assay and chromatography were used to study the occurrence of calcitonin gene-related peptide (CGRP) in a primitive teleost, the eel, Anguilla anguilla. Immunologically and biologically active CGRP-like molecules were found in brain, heart, kidney, liver, spleen and ultimobranchial... | ['Anguilla', 'Animals', 'Calcitonin', 'Calcitonin Gene-Related Peptide', 'Chromatography, High Pressure Liquid', 'Female', 'Humans', 'In Vitro Techniques', 'Male', 'Radioimmunoassay', 'Species Specificity'] | 14,700,750 | [['B01.050.150.900.493.338.282'], ['B01.050'], ['D06.472.699.150', 'D06.472.931.052', 'D12.644.400.095', 'D12.644.548.150', 'D12.776.631.650.095'], ['D12.644.400.097', 'D12.776.631.650.097'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['E01.370.384.700', 'E05.478.566.639', 'E... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acute Hemolytic Transfusion Reaction Due to the "Anti-E" Rhesus Antibody in a Patient with Crohn's Disease. | BACKGROUND: The rhesus (Rh) system is the second most important blood group system after ABO, with highly immunogenic antigens. Although the anti-E Rh antibody has been reported to cause hemolytic disease of the newborn and delayed hemolytic transfusion reactions, acute hemolytic transfusion reactions (AHTR) have been ... | ['Adult', 'Blood Group Antigens', 'Crohn Disease', 'Erythrocyte Transfusion', 'Humans', 'Male', 'Rh-Hr Blood-Group System', 'Transfusion Reaction'] | 31,532,084 | [['M01.060.116'], ['D23.050.301.290', 'D23.050.705.230'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['E02.095.135.140.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D23.050.301.290.775', 'D23.050.705.230.775'], ['C15.378.962', 'C20.920']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pigmented villonodular synovitis of the knee: A retrospective analysis of 214 cases at a UK tertiary referral centre. | AIMS: Pigmented villonodular synovitis (PVNS) is a rare, locally aggressive and potentially recurrent synovial disease. We present the largest single-centre experience of knee PVNS. Our aim was to evaluate our tertiary hospital's experience in the management of knee PVNS.PATIENTS AND METHODS: Retrospective data collect... | ['Adult', 'Aged', 'Arthroscopy', 'Female', 'Humans', 'Knee Joint', 'Male', 'Middle Aged', 'Recurrence', 'Retrospective Studies', 'Synovectomy', 'Synovitis, Pigmented Villonodular', 'Tertiary Care Centers', 'United Kingdom'] | 28,442,184 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['M01.060.116.630'], ['C23.550.291.937'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Ultrasound evaluation of visceral and subcutaneous fat reduction in morbidly obese subjects undergoing laparoscopic gastric banding, sleeve gastrectomy, and Roux-en-Y gastric bypass: a prospective comparison study. | BACKGROUND: Visceral fat (VF) plays a major role in the development of metabolic syndrome associated with obesity. The aim of our study is to compare VF and subcutaneous fat (SCF) reduction measured by ultrasonography (US) after laparoscopic adjustable gastric banding (LAGB), laparoscopic sleeve gastrectomy (LSG), and ... | ['Adult', 'Body Mass Index', 'Female', 'Gastrectomy', 'Gastric Bypass', 'Gastroplasty', 'Humans', 'Intra-Abdominal Fat', 'Male', 'Obesity, Morbid', 'Prospective Studies', 'Subcutaneous Fat', 'Treatment Outcome', 'Ultrasonography'] | 25,394,586 | [['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E04.210.419'], ['E02.650.500.062.249', 'E04.035.398.385', 'E04.062.249', 'E04.210.457.430'], ['E02.650.500.062.750', 'E04.062.750', 'E04.210.485'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.165... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Long-term evaluation of osseointegrated implants inserted at the time or after vertical ridge augmentation. A retrospective study on 123 implants with 1-5 year follow-up. | The purpose of the present study was to evaluate retrospectively, after 1 to 5 years of prosthetic loading, 123 implants consecutively inserted at the time of vertical ridge augmentation in 4 clinics. At the time of the implant surgery, 3 different techniques were used: the implants were allowed to protrude 2 to 7 mm f... | ['Adult', 'Aged', 'Alveolar Process', 'Alveolar Ridge Augmentation', 'Blood Coagulation', 'Bone Regeneration', 'Bone Resorption', 'Bone Transplantation', 'Dental Implantation, Endosseous', 'Dental Implants', 'Dental Prosthesis, Implant-Supported', 'Dental Restoration Failure', 'Follow-Up Studies', 'Humans', 'Longitudin... | 11,168,269 | [['M01.060.116'], ['M01.060.116.100'], ['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['E04.545.550.100', 'E06.645.550.100'], ['G09.188.390.150'], ['G11.427.213.140', 'G16.762.150.150'], ['C05.116.264', 'G11.427.213.150'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['E04.545.550.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Sudden unexpected death in young adults. Discrepancies between initiation of acute plaque complications and the onset of acute coronary death. | AIMS: To study the time relationship between the onset of coronary thrombosis and sudden unexpected cardiac death in young adults.METHODS AND RESULTS: Hearts of 11 young adults (< or = 35 years), who had died within 1h after onset of symptoms and presented with a coronary thrombotic occlusion were studied retrospective... | ['Acute Disease', 'Adult', 'Age Factors', 'Autopsy', 'Coronary Artery Disease', 'Coronary Thrombosis', 'Coronary Vessels', 'Death, Sudden, Cardiac', 'Female', 'Humans', 'Male', 'Myocardium', 'Retrospective Studies', 'Risk Factors'] | 12,208,223 | [['C23.550.291.125'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['C14.280.647.250.290', 'C14.907.355.830.220', 'C14.907.585.250.290'], ['A07.015.114.269', 'A07.015.908.194'], ['C14.28... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A calcium agonist, Bay k 8644, suppresses the embryotoxic effects induced by dihydropyridines calcium channel blockers in cultured rat embryos. | Day 9 rat embryos were exposed to 1,4-dihydropyridine calcium channel blockers; nifedipine (NIF), nicardipine (NIC) or nitrendipine (NIT), for 48 hr in the whole embryo culture system. There were dose-dependent growth retardation and abnormalities, predominantly in cardiovascular system. The three compounds exhibited v... | ['3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester', 'Animals', 'Calcium Channel Agonists', 'Calcium Channel Blockers', 'Culture Techniques', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Embryo, Mammalian', 'Female', 'Male', 'Nicardipine', 'Nifedipine... | 9,819,758 | [['D03.383.725.203.600', 'D03.383.725.547.900'], ['B01.050'], ['D27.505.519.562.124', 'D27.505.696.260.250', 'D27.505.954.411.793.205'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['E05.481.500'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['A16.254'], ['D03.383.725.203.510... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of albumin on itraconazole and ketoconazole antifungal activity: results of a dynamic in vitro study. | The relevance of intense protein binding to the antifungal activity of azole compounds is still a matter of debate. The influence of albumin on the antimicrobial activity of ketoconazole and itraconazole, which exhibit very strong plasma protein binding (99 and 99.8%), was evaluated in vitro. Candida albicans was expos... | ['Antifungal Agents', 'Candida albicans', 'Culture Media', 'Humans', 'Itraconazole', 'Ketoconazole', 'Microbial Sensitivity Tests', 'Protein Binding', 'Serum Albumin'] | 1,662,022 | [['D27.505.954.122.136'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['D27.720.470.305', 'E07.206'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.799.550', 'D03.383.606.530'], ['D03.383.606.560'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G02.111.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Screening proteins for NMR suitability. | NMR spectroscopy is a valuable tool in structural genomics. Identification of protein samples that are amenable to structure determination by NMR spectroscopy requires efficient screening. The preparation of multiple samples in parallel and screening by NMR is described. The method described is applicable to large stru... | ['Crystallography, X-Ray', 'Genomics', 'Magnetic Resonance Spectroscopy', 'Molecular Biology', 'Protein Conformation', 'Proteins'] | 24,590,717 | [['E05.196.309.742.225'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['E05.196.867.519'], ['H01.158.201.636', 'H01.158.273.343.595', 'H01.181.122.650'], ['G02.111.570.820.709'], ['D12.776']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[A rare variant of chromosome 1 in the house mouse: the presence of 2 supernumerary heterochromatin segments]. | An abnormal chromosome 1 with two extra interstitial heterochromatin segments was found in the karyotype of a house mouse from the Maritime Territory. Until recently, variants of the abnormal chromosome 1 with the only extra C-block were known in house mouse of some European populations. Sizes of the abnormal chromosom... | ['Animals', 'Chromosome Aberrations', 'Chromosome Banding', 'Genetic Variation', 'Heterochromatin', 'Karyotyping', 'Male', 'Mice', 'Siberia'] | 3,360,320 | [['B01.050'], ['C23.550.210', 'G05.365.590.175'], ['E01.370.225.500.385.130', 'E01.370.225.500.620.670.130', 'E01.370.225.750.600.670.130', 'E05.200.500.385.130', 'E05.200.500.620.670.130', 'E05.200.750.600.670.130', 'E05.242.385.130', 'E05.393.285.130'], ['G05.365'], ['A11.284.430.106.279.345.190.160.180.383', 'D12.77... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Overactive performance monitoring in obsessive-compulsive disorder: ERP evidence from correct and erroneous reactions. | Obsessive-compulsive disorder (OCD) has repeatedly been associated with hyperactivity in fronto-striatal brain regions and regions related to performance monitoring. The aim of the current study was to further investigate electrophysiological correlates of performance monitoring. Specifically, we intended to replicate ... | ['Adult', 'Attention', 'Brain Mapping', 'Cerebral Cortex', 'Choice Behavior', 'Control Groups', 'Electroencephalography', 'Electrooculography', 'Evoked Potentials', 'Female', 'Functional Laterality', 'Humans', 'Male', 'Neural Pathways', 'Neuropsychological Tests', 'Obsessive-Compulsive Disorder', 'Pattern Recognition, ... | 18,514,679 | [['M01.060.116'], ['F02.830.104.214'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['F02.463.785.373.346'], ['E05.318.370.074', 'E05.581.500.149'], ['E01.370.376.300', 'E01.370.405.245'], ['E01.370.380.230.285', 'E01.370.405.245.787.285'], ['G07.265.216.50... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genetic change for clinical mastitis in Norwegian cattle: a threshold model analysis. | Records of clinical mastitis on 1.6 million first-lactation daughters of 2,411 Norwegian Cattle sires that were progeny tested from 1978 through 1998 were analyzed with a threshold model. The main objective was to infer genetic change for the disease in the population. A Bayesian approach via Gibbs sampling was used. T... | ['Animals', 'Bayes Theorem', 'Breeding', 'Cattle', 'Female', 'Genetic Variation', 'Lactation', 'Linear Models', 'Male', 'Mastitis, Bovine', 'Models, Genetic', 'Norway'] | 12,613,880 | [['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['E05.820.150', 'G05.090'], ['B01.050.150.900.649.313.500.380.271'], ['G05.365'], ['G08.686.523', 'G08.686.702.500'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Social deprivation and exposure to health promotion. A study of the distribution of health promotion resources to schools in England. | BACKGROUND: Area deprivation is a known determinant of health. It is also known that area deprivation is associated with lower impact health promotion. It is less well known, however, whether deprived areas are less responsive to health promotion, or whether they are less exposed. Using data from a national, school-bas... | ['Adolescent', 'Child', 'Cross-Sectional Studies', 'England', 'Female', 'Health Promotion', 'Humans', 'Male', 'Papillomavirus Infections', 'Papillomavirus Vaccines', 'Poverty Areas', 'Resource Allocation'] | 20,698,980 | [['M01.060.057'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.542.363.300'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.925.256.650', 'C01.925.928.725'], ['D20.215.894.899.498'], ['I01.880.853.996.535.550',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Increased biomass accumulation in maize grown in mixed nitrogen supply is mediated by auxin synthesis. | The use of mixed nitrate and ammonium as a nitrogen source can improve plant growth. Here, we used metabolomics and transcriptomics to study the underlying mechanisms. Maize plants were grown hydroponically in the presence of three forms of nitrogen (nitrate alone, 75%/25% nitrate/ammonium, and ammonium alone). Plants ... | ['Biomass', 'Indoleacetic Acids', 'Nitrogen', 'Zea mays'] | 30,759,246 | [['G16.500.275.157.100', 'N06.230.124.100'], ['D03.066.288', 'D03.633.100.473.404'], ['D01.268.604', 'D01.362.625'], ['B01.650.940.800.575.912.250.822.966']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Proline dehydrogenase promotes senescence through the generation of reactive oxygen species. | Cellular senescence is a complex stress response characterized by permanent loss of proliferative capacity and is implicated in age-related disorders. Although the transcriptional activity of p53 (encoded by TP53) is known to be vital for senescence induction, the downstream effector genes critical for senescence remai... | ['Acetylcysteine', 'Cell Line', 'Cellular Senescence', 'DNA Damage', 'Fibroblasts', 'Furans', 'Humans', 'Proline Oxidase', 'RNA, Small Interfering', 'Reactive Oxygen Species', 'Transgenes', 'Tumor Suppressor Protein p53'] | 28,264,926 | [['D02.886.030.230.259', 'D12.125.166.230.259'], ['A11.251.210'], ['G04.043'], ['G05.200'], ['A11.329.228'], ['D03.383.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.682.662.640', 'D08.811.682.664.500.810'], ['D13.150.650.700', 'D13.444.735.150.700', 'D13.444.735.790.552.875'], ['D01.339.431', 'D01.6... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endoplasmic reticulum stress triggers autophagy in malignant glioma cells undergoing cyclosporine a-induced cell death. | Autophagy is a conserved, self-digestion process that is activated in response to nutrient limitation but acting also as an alternative death mechanism under certain conditions. It is accompanied by the progressive formation of vesicle structures from autophagosomes to autophagolysosomes orchestrated by autophagy effec... | ['Animals', 'Apoptosis', 'Autophagy', 'Brain Neoplasms', 'Cell Line, Tumor', 'Cell Survival', 'Cyclosporine', 'Endoplasmic Reticulum Stress', 'Glioma', 'Humans', 'Rats', 'TOR Serine-Threonine Kinases', 'eIF-2 Kinase'] | 22,580,614 | [['B01.050'], ['G04.146.954.035'], ['G04.011'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['G04.434'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.90... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Impact of Livestrong® at the YMCA for Cancer Survivors. | OBJECTIVES: To determine the clinical significance of pre- and post-exercise rehabilitation physical and psychosocial outcomes of the Livestrong® at the YMCA program.SAMPLE & SETTING: 158 participants at the YMCA of the Fox Cities in Appleton, Wisconsin, were analyzed for pre- and postparticipation physical outcome... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cancer Survivors', 'Community Health Services', 'Exercise', 'Exercise Therapy', 'Female', 'Health Promotion', 'Humans', 'Male', 'Middle Aged', 'Neoplasms', 'Quality of Life', 'Wisconsin'] | 30,339,155 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.860.350'], ['N02.421.143'], ['G11.427.410.698.277', 'I03.350'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04'], ... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice. | In Alzheimer's disease (AD) brains, the microtubule-associated protein tau and amyloid-â (Aâ) deposit as intracellular neurofibrillary tangles (NFTs) and extracellular plaques, respectively. Tau deposits are furthermore found in a significant number of frontotemporal dementia cases. These diseases are characterized by ... | ['Aging', 'Amino Acid Sequence', 'Animals', 'Disease Progression', 'Gliosis', 'Humans', 'Immunity', 'Immunization', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Molecular Sequence Data', 'Neurofibrillary Tangles', 'Phosphorylation', 'Vaccination', 'tau Proteins'] | 22,174,735 | [['G07.345.124'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['C23.550.291.656'], ['C23.550.369'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['B01.050.150.900.649.313.992.635.50... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Male specific genes from dioecious white campion identified by fluorescent differential display. | Fluorescent differential display (FDD) has been used to screen for cDNAs that are differentially up-regulated in male flowers of the dioecious plant Silene latifolia in which an X/Y chromosome system of sex determination operates. To adapt FDD to the cloning of large numbers of differential cDNAs, a novel method of con... | ['Blotting, Southern', 'Chromosomes', 'Cloning, Molecular', 'DNA, Complementary', 'Fluorescent Dyes', 'Gene Expression Profiling', 'Gene Expression Regulation, Developmental', 'Gene Expression Regulation, Plant', 'Genes, Plant', 'Genetic Complementation Test', 'Molecular Sequence Data', 'RNA, Plant', 'Reproduction', 'S... | 12,040,104 | [['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['E05.393.332'], ['G05.308.310'], ['G05.308.375'], ['G05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Accuracy of SNPs to predict risk of HLA alleles associated with drug-induced hypersensitivity events across racial groups. | AIM: To evaluate the potential usefulness of selected SNPs to predict specific HLA alleles that are associated with drug-induced hypersensitivity reactions (HSR) in different ethnic groups.METHODS & RESULTS: Five specific HLA alleles known to predict HSR were tagged by seven SNPs (rs1061235-HLA-A*31:01; rs2395029-HLA-B... | ['African Americans', 'Alleles', 'Asian Continental Ancestry Group', 'Drug Hypersensitivity', 'European Continental Ancestry Group', 'Genotype', 'HLA-B Antigens', 'HLA-DQ alpha-Chains', 'Hispanic Americans', 'Humans', 'Polymorphism, Single Nucleotide'] | 26,083,016 | [['M01.686.508.100.100', 'M01.686.754.100'], ['G05.360.340.024.340.030'], ['M01.686.508.200'], ['C20.543.206', 'C25.100.468'], ['M01.686.508.400'], ['G05.380'], ['D12.776.395.550.489.500', 'D12.776.543.550.439.500', 'D23.050.301.500.100.500', 'D23.050.301.500.450.380', 'D23.050.705.552.100.500', 'D23.050.705.552.450.38... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Outcomes of percutaneous endoscopic gastrostomy among older adults in a community setting. | OBJECTIVE: Percutaneous endoscopic gastrostomy (PEG) has become the preferred method to provide enteral tube feeding to older adults who have difficulty eating, but the impact of PEG on patient outcomes is poorly understood. The objective of this study was to describe changes in nutrition, functional status, and health... | ['Activities of Daily Living', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Attitude to Health', 'Enteral Nutrition', 'Female', 'Gastroscopy', 'Gastrostomy', 'Geriatric Assessment', 'Humans', 'Male', 'Middle Aged', 'Nutritional Status', 'Outcome and Process Assessment, Health Care', 'Prospective Studies', 'Quality of L... | 10,983,903 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.150', 'N05.300.150'], ['E02.421.360', 'E02.642.500.360'], ['E01.370.372.250.250.325', 'E01.370.388.250.250.250.320', 'E04.210.240.250.320', 'E04.502.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
'Dicty dynamics': Dictyostelium motility as persistent random motion. | We model the motility of Dictyostelium cells in a systematic data-driven manner. We deduce a minimal dynamical model that reproduces the statistical features of experimental trajectories. These are trajectories of the centroid of the cell perimeter, which is more sensitive to pseudopod activity than the usual tracking ... | ['Cell Movement', 'Dictyostelium', 'Models, Biological', 'Models, Statistical', 'Normal Distribution', 'Periodicity', 'Stochastic Processes'] | 21,610,290 | [['G04.198', 'G07.568.500.180'], ['B01.046.550.200.300'], ['E05.599.395'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.318.740.994.500', 'G17.820.500', 'N05.715.360.750.750.565', 'N06.850.520.830.994.500'], ['G01.910.645', 'G07.180.562'], ['E05.318.740.996', 'G17.830', 'N05.7... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Nutritional and metabolic consequences of the early Maillard reaction of heat treated milk in the pig. Significance for man. | BACKGROUND: During the processing of foods, the Maillard reaction may occur contributing to altering the nutritional value of proteins. In dairy products the formation of lactuloselysine reduces the availability of lysine but the effects on the other nutrients are not very well known.AIM OF THE STUDY: Determination of ... | ['Amino Acids', 'Animals', 'Feces', 'Female', 'Freeze Drying', 'Hot Temperature', 'Lactulose', 'Lysine', 'Maillard Reaction', 'Milk', 'Milk Proteins', 'Models, Animal', 'Nutritive Value', 'Swine', 'Time Factors'] | 11,990,002 | [['D12.125'], ['B01.050'], ['A12.459'], ['E01.370.225.500.620.760.160.260', 'E01.370.225.750.600.760.160.260', 'E02.792.156.260', 'E05.200.500.620.760.160.260', 'E05.200.750.600.760.160.260', 'E05.760.156.260'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Quercetin and interferon-beta modulate immune response(s) in peripheral blood mononuclear cells isolated from multiple sclerosis patients. | The study is aimed to determine the role of quercetin (3,3'4',5,7-pentahydroxy flavone), alone and in combination with human interferon-beta (IFN-beta), in modulating the immune response(s) of peripheral blood mononuclear cells (PBMC) isolated from multiple sclerosis (MS) patients and from normal healthy subjects. PBMC... | ['Adult', 'Antioxidants', 'Case-Control Studies', 'Cell Proliferation', 'Cytokines', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Immunologic Factors', 'Interferon-beta', 'Leukocytes, Mononuclear', 'Male', 'Matrix Metalloproteinase 1', 'Matrix Metalloproteinase 9', 'Middle Aged', 'Multiple Sclerosis', 'Quer... | 18,926,575 | [['M01.060.116'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The mechanism of heme oxygenase-1 action involved in the enhancement of neurotrophic factor expression. | Heme oxygenase-1 (HO-1) is up-regulated in response to oxidative stress and catalyzes the degradation of pro-oxidant heme to carbon monoxide (CO), iron and bilirubin. Bilirubin is a potent antioxidant and neuroprotectant. Neurotrophic factors of BDNF and GDNF also play important roles in survival and morphological diff... | ['Animals', 'Astrocytes', 'Brain', 'Brain-Derived Neurotrophic Factor', 'Cell Death', 'Cells, Cultured', 'Cerebral Cortex', 'Coculture Techniques', 'Dopamine', 'Glial Cell Line-Derived Neurotrophic Factor', 'Heme Oxygenase-1', 'Humans', 'Mesencephalon', 'Microglia', 'Neurons', 'RNA, Messenger', 'Rats', 'Rats, Transgeni... | 19,925,812 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['A08.186.211'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['G04.146'], ['A11.251'], ['A08.186.211.200.885.287.500'], ['E05.481.500.374'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D1... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Facilitatory or inhibitory nontarget effects in the location-cuing paradigm. | The effect of nontargets on the identification of targets in the location-cuing paradigm was investigated in order to determine whether observers consistently allocate their attention to a validly cued location and whether the effect of nontargets is to facilitate or to inhibit performance. In four experiments, the eff... | ['Adult', 'Attention', 'Eye Movements', 'Female', 'Humans', 'Male', 'Psychomotor Performance', 'Random Allocation', 'Visual Perception'] | 9,262,415 | [['M01.060.116'], ['F02.830.104.214'], ['G11.427.410.140', 'G14.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['F02.463.593.932']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Protein quantitation and analysis of purity. | The accurate quantitation of proteins and an analysis of their purity are essential in numerous areas of scientific research, and are a critical factor in many clinical applications. The large and varied number of techniques employed for this purpose is therefore not surprising. The selection of a suitable assay is dep... | ['Absorption', 'Animals', 'Blotting, Western', 'Calibration', 'Cattle', 'Electrophoresis, Polyacrylamide Gel', 'Enzyme-Linked Immunosorbent Assay', 'Polymerase Chain Reaction', 'Proteins', 'Quinolines', 'Spectrophotometry, Ultraviolet', 'Staining and Labeling'] | 20,978,969 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.978.155'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.401.402', 'E05.301.300.319'], ['E05.478.566.350.170', 'E05.478.566.3... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An extracytoplasmic function sigma factor-dependent periplasmic glutathione peroxidase is involved in oxidative stress response of Shewanella oneidensis. | BACKGROUND: Bacteria use alternative sigma factors (ós) to regulate condition-specific gene expression for survival and Shewanella harbors multiple ECF (extracytoplasmic function) ó genes and cognate anti-sigma factor genes. Here we comparatively analyzed two of the rpoE-like operons in the strain MR-1: rpoE-rseA-rseB-... | ['Culture Media', 'Gene Deletion', 'Glutathione Peroxidase', 'Hydrogen Peroxide', 'Oxidants', 'Oxidative Stress', 'Paraquat', 'Periplasmic Proteins', 'Salinity', 'Shewanella', 'Sigma Factor', 'Stress, Physiological', 'Temperature'] | 25,887,418 | [['D27.720.470.305', 'E07.206'], ['G05.365.590.762.320', 'G05.558.800.320'], ['D08.811.682.732.500'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D27.720.642', 'D27.888.569.540'], ['G03.673', 'G07.775.750'], ['D03.383.725.762.621'], ['D12.776.090.650', 'D12.776.09... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Controlled steroid delivery via bioabsorbable stent: safety and performance in a rabbit model. | BACKGROUND: Middle turbinate lateralization, adhesions, and inflammation are causes of suboptimal sinus patency following surgery. A bioabsorbable drug-eluting stent has been developed to maintain sinus patency while providing controlled steroid delivery to the sinus mucosa. The aim of this study was to characterize th... | ['Absorbable Implants', 'Animals', 'Anti-Inflammatory Agents', 'Chromatography, High Pressure Liquid', 'Drug-Eluting Stents', 'Endoscopy', 'Infusion Pumps, Implantable', 'Models, Animal', 'Mometasone Furoate', 'Mycoses', 'Nasal Mucosa', 'Paranasal Sinuses', 'Pregnadienediols', 'Prosthesis-Related Infections', 'Rabbits'... | 19,958,608 | [['E07.695.025'], ['B01.050'], ['D27.505.954.158'], ['E05.196.181.400.300'], ['E07.695.750.500'], ['E01.370.388.250', 'E04.502.250'], ['E07.505.254', 'E07.858.082.505.254'], ['E05.598'], ['D04.210.500.745.432.719.526'], ['C01.150.703'], ['A04.531.520', 'A04.760.600', 'A10.615.550.760.600'], ['A04.531.621'], ['D04.210.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Submitogenic concentrations of anti-CD3 monoclonal antibody exert antiapoptotic effects in preactivated CD4+ but not CD8+ human T cells. | Immunological memory has been ascribed to the presence of long-lived memory cells. The mechanisms underlying their generation are not completely understood, but dependence on antigen persistence has been discussed in this regard. However, in spite of in vivo evidence favoring this model, studies on TCR/CD3 stimulation ... | ['Antibodies, Monoclonal', 'Apoptosis', 'CD4-Positive T-Lymphocytes', 'CD8-Positive T-Lymphocytes', 'Cell Survival', 'Cells, Cultured', 'Flow Cytometry', 'Humans', 'Immunologic Memory', 'Kinetics', 'Lymphocyte Activation', 'Receptor-CD3 Complex, Antigen, T-Cell'] | 9,384,680 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G04.146.954.035'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['G04... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glycyrrhizin inhibits influenza A virus uptake into the cell. | We investigated the mechanism by which glycyrrhizin (GL), the main active component of licorice roots, protects cells from infection with influenza A virus (IAV). We found that GL treatment leads to a clear reduction in the number of IAV-infected human lung cells as well as a reduction in the CCID50 titer by 90%. The a... | ['Antiviral Agents', 'Cell Line', 'Epithelial Cells', 'Glycyrrhiza', 'Glycyrrhizic Acid', 'Humans', 'Influenza A virus', 'Virus Internalization'] | 19,416,738 | [['D27.505.954.122.388'], ['A11.251.210'], ['A11.436'], ['B01.650.940.800.575.912.250.401.300'], ['D02.455.849.919.530.466'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.405.400'], ['G06.920.881']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Motor asymmetries in preterm infants: effects of prematurity and illness. | Two types of motor asymmetry, postural asymmetry and lateral head turning, were assessed in 3 groups of preterm infants, one of which had experienced respiratory distress syndrome (RDS) in the postnatal period. Results reveal that maintenance of a right postural asymmetry is present as early as 34 weeks conceptional ag... | ['Age Factors', 'Child Development', 'Functional Laterality', 'Head', 'Humans', 'Infant', 'Infant, Newborn', 'Infant, Premature', 'Movement', 'Posture', 'Respiratory Distress Syndrome, Newborn'] | 7,054,013 | [['N05.715.350.075', 'N06.850.490.250'], ['F01.525.200', 'G07.345.374.750'], ['F02.830.297.425', 'G11.561.225.425'], ['A01.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['G07.568', 'G11.427.410'], ['G11.427.695'], ['C08.381.840.500', 'C08.618.840.... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[The Yale-Brown Scale: instrument for assessing the severity of obsessive-compulsive disorders]. | The paper presents characteristics and evaluation of the Yale-Brown Scale, its clinical value in assessing severity of obsessive compulsive disorders. The Yale-Brown Scale is a semistructured interview. The scale consists of 10 items, rated from 0 (no symptoms) to 4 (extreme symptoms). There are separate ratings for se... | ['Adult', 'Female', 'Humans', 'Male', 'Obsessive-Compulsive Disorder', 'Psychiatric Status Rating Scales', 'Severity of Illness Index'] | 9,594,585 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.080.600'], ['F04.711.513.653'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.520.308.980.438.475.364.500']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Improve the organ recovery system. | Following the revised 1987 AGA, at least to the extent of correct interaction with donor families, can reduce organ waiting times to nominal within a decade, and could save about $360 million per year. Fear of lawsuits is no excuse for not implementing the revised AGA guidelines. Following the 1987 AGA revision in its ... | ['Guideline Adherence', 'Health Care Costs', 'Humans', 'Informed Consent', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Practice Guidelines as Topic', 'Public Opinion', 'Tissue and Organ Procurement'] | 12,108,994 | [['N04.761.337', 'N05.715.360.395'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.473.650.718', 'I01.880.604.583.427', 'N03.706.437.650.312', 'N03.706.535.489'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E02.870.500', 'E04.936.450.485', 'E04.950.... | ['Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
A circularly permuted myoglobin possesses a folded structure and ligand binding similar to those of the wild-type protein but with a reduced thermodynamic stability. | A circular permutein of sperm whale myoglobin in which the G helix is C-terminal, the H helix is N-terminal, and 16 amino acids link the H helix to the A helix has been expressed in Escherichia coli. The permutein sequence begins with Gly121 (using the numbering scheme for the wild-type protein) and terminates with Pro... | ['Amino Acid Sequence', 'Animals', 'Circular Dichroism', 'Escherichia coli', 'Ligands', 'Molecular Sequence Data', 'Myoglobin', 'Nuclear Magnetic Resonance, Biomolecular', 'Protein Binding', 'Protein Denaturation', 'Protein Engineering', 'Protein Folding', 'Protein Structure, Secondary', 'Protein Structure, Tertiary', ... | 12,403,634 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.196.867.151'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D27.720.470.480'], ['L01.453.245.667'], ['D12.776.210.500.588', 'D12.776.422.316.940'], ['E05.196.867.519.550'], ['G02.111.679', 'G03.808'], ['G01.154.651.750.500', 'G02.111.688.750.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Genomewide identification of Pseudomonas syringae pv. tomato DC3000 promoters controlled by the HrpL alternative sigma factor. | The ability of Pseudomonas syringae pv. tomato DC3000 to parasitize tomato and Arabidopsis thaliana depends on genes activated by the HrpL alternative sigma factor. To support various functional genomic analyses of DC3000, and specifically, to identify genes involved in pathogenesis, we developed a draft sequence of DC... | ['Bacterial Proteins', 'DNA Transposable Elements', 'DNA-Binding Proteins', 'Genes, Reporter', 'Genome, Bacterial', 'Lycopersicon esculentum', 'Markov Chains', 'Models, Genetic', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Oligonucleotide Array Sequence Analysis', 'Open Reading Frames', 'Promoter Regions,... | 11,854,524 | [['D12.776.097'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['D12.776.260'], ['G05.360.340.024.340.435'], ['G05.360.340.358.207'], ['B01.650.940.800.575.912.250.908.500.322'], ['E05.318.740.600.500', 'E05.318.740.996.500', 'G17.830.500', 'N05.715.360.750.6... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Standardized test mixture for the characterization of comprehensive two-dimensional gas chromatography columns: the Phillips mix. | A novel column characterization test mixture is developed for use in comprehensive two-dimensional gas chromatography (GC x GC). This mixture has been named the "Phillips mix" in honor of the late professor John B. Phillips, the father of GC x GC. The mixture comprises a series of homologous compounds from structural g... | ['Chromatography, Gas'] | 14,650,620 | [['E05.196.181.349']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of swimming on bone modeling and composition in young adult rats. | The purpose of this study was to investigate the adaptability of long bones of young adult rats to the stress of chronic aquatic exercise. Twenty-eight female Sabra rats (12 weeks old) were randomly assigned to two groups and treatments: exercise (14 rats) and sedentary control (14 rats) matched for age and weight. Exe... | ['Animals', 'Body Weight', 'Bone Density', 'Bone Development', 'Bone and Bones', 'Evaluation Studies as Topic', 'Female', 'Minerals', 'Physical Conditioning, Animal', 'Rats', 'Swimming'] | 2,224,593 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G11.427.100'], ['G07.345.500.325.377.625.050.500', 'G11.427.578.050.500'], ['A02.835.232', 'A10.165.265'], ['E05.337', 'N05.715.360.335'], ['D01.578'], ['G11.427.410.698.277.280'], ['B01.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Alteration of anomeric preference of glucose-induced insulin secretion by glyceraldehyde. | Glucokinase activity in pancreatic islets was dose-dependently inactivated by D-glyceraldehyde, whereas islet hexokinase activity was not altered. In untreated islets, alpha-D-glucose stimulated insulin secretion more efficiently than beta-D-glucose at a glucose concentration of 10 mM. However, glyceraldehyde highly at... | ['Animals', 'Enzyme Activation', 'Erythrocytes', 'Female', 'Glucokinase', 'Glucose', 'Glyceraldehyde', 'Hexokinase', 'Insulin', 'Insulin Secretion', 'Islets of Langerhans', 'Isomerism', 'Kinetics', 'Liver', 'Models, Biological', 'Phosphorylation', 'Rats', 'Rats, Wistar'] | 8,412,503 | [['B01.050'], ['G02.111.263', 'G03.328'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D08.811.913.696.620.250'], ['D09.947.875.359.448'], ['D02.047.587', 'D09.947.875.894.449'], ['D08.811.913.696.620.300'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.442', 'G07.475'], ['A03.734.414', ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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