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Coping in Patients With Incurable Lung and Gastrointestinal Cancers: A Validation Study of the Brief COPE. | CONTEXT: Patients with incurable cancer engage in several coping styles to manage the impact of cancer and its treatment. The Brief COPE is a widely used measure intended to capture multiple and distinct types of coping. The Brief COPE has not been validated among patients with incurable cancer.OBJECTIVES: We sought to... | ['Adaptation, Psychological', 'Aged', 'Anxiety', 'Depression', 'Female', 'Gastrointestinal Neoplasms', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Palliative Care', 'Psychometrics', 'Quality of Life', 'Stress, Psychological', 'Surveys and Questionnaires'] | 27,725,249 | [['F01.058'], ['M01.060.116.100'], ['F01.470.132'], ['F01.145.126.350'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['E02.760.666', 'N02.421.585.666'], ['F04.711.780'], ['I01.800', 'K01.7... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Sampling date, leaf age and root size: implications for the study of plant C:N:p stoichiometry. | Plant carbon : nitrogen : phosphorus (C:N:P) ratios are powerful indicators of diverse ecological processes. During plant development and growth, plant C:N:P stoichiometry responds to environmental conditions and physiological constraints. However, variations caused by effects of sampling (i.e. sampling date, leaf age ... | ['Carbon', 'Nitrogen', 'Phosphorus', 'Plant Leaves', 'Plant Roots', 'Time Factors'] | 23,565,234 | [['D01.268.150'], ['D01.268.604', 'D01.362.625'], ['D01.268.666'], ['A18.024.812'], ['A18.400'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Season of birth affects short- and long-term survival. | Recent research findings have highlighted the importance of early life conditions as risk factors for adult diseases and therefore determinants of subsequent survival. Given that individuals born during different seasons in seasonal environments experience different early-developmental conditions, an analysis of the ef... | ['Analysis of Variance', 'Cause of Death', 'Environment', 'Geography', 'History, 17th Century', 'History, 18th Century', 'History, 19th Century', 'Humans', 'Infant Mortality', 'Infant, Newborn', 'Nutrition Surveys', 'Parturition', 'Seasons', 'Spain', 'Survival Rate'] | 18,186,510 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['G16.500.275', 'N06.230'], ['H01.277.500'], ['K01.400.504.750'], ['K01.400.504.875'], ['K01.400.504.937'], ['B01.050.150.900.649.313.988.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Humanities [K]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Predictive toxicology modeling: protocols for exploring hERG classification and Tetrahymena pyriformis end point predictions. | The inclusion and accessibility of different methodologies to explore chemical data sets has been beneficial to the field of predictive modeling, specifically in the chemical sciences in the field of Quantitative Structure-Activity Relationship (QSAR) modeling. This study discusses using contemporary protocols and QSAR... | ['Animals', 'ERG1 Potassium Channel', 'Ether-A-Go-Go Potassium Channels', 'Models, Molecular', 'Quantitative Structure-Activity Relationship', 'Support Vector Machine', 'Tetrahymena pyriformis', 'Toxicology'] | 22,642,982 | [['B01.050'], ['D12.776.157.530.400.600.900.249.500', 'D12.776.543.550.450.750.900.249.500', 'D12.776.543.585.400.750.900.249.500'], ['D12.776.157.530.400.600.900.249', 'D12.776.543.550.450.750.900.249', 'D12.776.543.585.400.750.900.249'], ['E05.599.595'], ['G02.111.830.500', 'G07.690.773.997.500'], ['G17.035.250.500.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Diagnostic Dilemma in a Case of Diffuse Pulmonary Arteriovenous Malformation With Vascular Stenosis. | Diffuse pulmonary arteriovenous malformation is a rare entity, the exact incidence of which is unknown. It can be limited to a single lobe, or it can diffusely involve one or both the lungs. Early diagnosis and treatment is crucial, as it is associated with increased frequency of thoracic and neurologic complications. ... | ['Abnormalities, Multiple', 'Adolescent', 'Arteriovenous Malformations', 'Computed Tomography Angiography', 'Echocardiography', 'Embolization, Therapeutic', 'Endovascular Procedures', 'Humans', 'Male', 'Pulmonary Artery', 'Pulmonary Veins', 'Stenosis, Pulmonary Artery'] | 31,877,288 | [['C16.131.077'], ['M01.060.057'], ['C14.240.850.750', 'C14.907.150', 'C16.131.240.850.750'], ['E01.370.350.350.810.335', 'E01.370.350.567.250', 'E01.370.350.600.350.700.810.335', 'E01.370.350.700.700.810.335', 'E01.370.350.700.810.810.568', 'E01.370.350.825.810.810.499'], ['E01.370.350.130.750', 'E01.370.350.850.220',... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cost-effectiveness of alternative strategies for integrating MRI into breast cancer screening for women at high risk. | BACKGROUND: Magnetic resonance imaging (MRI) is recommended for women at high risk for breast cancer. We evaluated the cost-effectiveness of alternative screening strategies involving MRI.METHODS: Using a microsimulation model, we generated life histories under different risk profiles, and assessed the impact of screen... | ['Adult', 'Breast Neoplasms', 'Cost-Benefit Analysis', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Mass Screening', 'Middle Aged', 'Monte Carlo Method', 'Risk Factors'] | 25,137,022 | [['M01.060.116'], ['C04.588.180', 'C17.800.090.500'], ['N03.219.151.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.780.500'], ['M01.060.116.630'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Long-term prognosis of Chinese patients with a lacunar infarct associated with small vessel disease: a five-year longitudinal study. | RATIONALE: Lacunar infarct associated with small vessel disease is a common stroke subtype in China and has a favorable short-term prognosis. Data on its long-term prognosis among Chinese patients are lacking.AIMS: We aimed to study its long-term prognosis and predictors for poor outcomes.DESIGN: We followed up to 75 c... | ['Age Factors', 'Aged', 'Asian Continental Ancestry Group', 'Blood Vessels', 'Brain Infarction', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Prognosis', 'Recurrence', 'Risk Factors'] | 19,383,047 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.686.508.200'], ['A07.015'], ['C10.228.140.300.150.477', 'C10.228.140.300.775.200', 'C14.907.253.092.477', 'C14.907.253.855.200', 'C23.550.513.355.250', 'C23.550.717.489.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500',... | ['Health Care [N]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
P53 in breast carcinomas: association between presence of mutation and immunohistochemical expression using a semiquantitative approach. | The aim of this study was to evaluate the concordance between the presence of p53 mutations in breast carcinomas expressing the protein by immunohistochemistry. A series of 60 breast carcinomas was evaluated by immunohistochemistry using monoclonal antibodies against p53 protein (DO 7 and PAb 1801). Twenty cases classi... | ['Adult', 'Aged', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'DNA, Neoplasm', 'Female', 'Genes, p53', 'Humans', 'Immunoenzyme Techniques', 'Middle Aged', 'Mutation, Missense', 'Polymerase Chain Reaction', 'Polymorphism, Single-Stranded Conformational', 'Tumor Suppressor Protein p53'] | 9,894,246 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['D13.444.308.425'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415.400.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Theorising stigma and the experiences of injecting drug users in Australia. | This paper examines the stigma of injecting drug use as an underlying factor in the poor health status of Australian injecting drug users. Drawing on various models of stigma described in the literature, we examine injecting drug users' experiences. As a case study, examples from Victorian (specifically Melbourne) poli... | ['Attitude to Health', 'Australia', 'Drug Users', 'HIV Infections', 'Health Status Disparities', 'Healthcare Disparities', 'Hepatitis C, Chronic', 'Humans', 'Models, Psychological', 'Patient Acceptance of Health Care', 'Social Stigma', 'Substance Abuse, Intravenous', 'Victoria'] | 21,128,572 | [['F01.100.150', 'N05.300.150'], ['Z01.639.100', 'Z01.678.100.373'], ['M01.169'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['N04.590.374.380', 'N05.300.493'], ['C01.221.2... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Caecal bascule--a potential clinical and radiological pitfall. Case reports. | Caecal volvulus is usually associated with a twisted caecum, seen to occupy the umbilical area or left hypochondrium on radiography. Caecal bascule refers to the form of volvulus in which the distended caecum is situated within the pelvis. The caecal bascule type of obstruction is uncommon, and clinical and radiologica... | ['Adult', 'Cecal Diseases', 'Female', 'Humans', 'Intestinal Obstruction', 'Radiography'] | 715,600 | [['M01.060.116'], ['C06.405.469.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531'], ['E01.370.350.700']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Rational design, synthesis, and evaluation of tetrahydroxamic acid chelators for stable complexation of zirconium(IV). | Metals of interest for biomedical applications often need to be complexed and associated in a stable manner with a targeting agent before use. Whereas the fundamentals of most transition-metal complexation processes have been thoroughly studied, the complexation of Zr(IV) has been somewhat neglected. This metal has rec... | ['Chelating Agents', 'Coordination Complexes', 'Crystallography, X-Ray', 'Deferoxamine', 'Edetic Acid', 'Ferric Compounds', 'Hydroxamic Acids', 'Kinetics', 'Positron-Emission Tomography', 'Radioisotopes', 'Zirconium'] | 24,740,517 | [['D27.505.519.914.500', 'D27.720.832.500'], ['D01.234', 'D02.257'], ['E05.196.309.742.225'], ['D02.092.570.394.265', 'D02.241.511.372.265'], ['D02.092.782.258.368.250', 'D02.241.081.018.253'], ['D01.490.100'], ['D02.092.570.394', 'D02.241.511.372'], ['G01.374.661', 'G02.111.490'], ['E01.370.350.350.800.700', 'E01.370.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biotechnological production and functional characterization of leukocytic cytokine(s) with cytotoxic effect on resting but not activated thymocytes. | In the present report we describe the analysis of suppressive and cytotoxic factor(s) derived from Con A-induced porcine leukocyte culture supernatant solution(s) (PCAS). The supernatant solution(s) had been produced on a biotechnological scale using porcine peripheral blood leukocytes isolated from 200 to 1000 1 of po... | ['Animals', 'Biological Products', 'Concanavalin A', 'Cytokines', 'Cytotoxicity, Immunologic', 'Hot Temperature', 'Hydrogen-Ion Concentration', 'Immune Tolerance', 'Immunosuppressive Agents', 'Interleukin-2', 'Lectins', 'Lymphocyte Activation', 'Peanut Agglutinin', 'Swine', 'T-Lymphocytes', 'Thymus Gland', 'Trypsin'] | 3,891,593 | [['B01.050'], ['D20.215'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G12.287'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G02.300'], ['G12.535.425'], ['D27.505.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Histochemical and ultrastructural study of renal cortical necrosis in rats treated with oestrone + vasopressin, and its prevention with a vasopressin antagonist. | Renal cortical necrosis was induced by the administration of vasopressin to oestrogen-pretreated rats. Histochemical (succinic dehydrogenase, trichrome, perjod acid Schiff) and electronmicroscopic methods were applied to examine how the vasopressin antagonist d(CH2)5Tyr(Met)AVP influences the development of this renal ... | ['Animals', 'Arginine Vasopressin', 'Disease Models, Animal', 'Estrone', 'Histocytochemistry', 'Kidney', 'Kidney Cortex Necrosis', 'Lypressin', 'Male', 'Microscopy, Electron', 'Rats', 'Rats, Inbred Strains'] | 3,814,500 | [['B01.050'], ['D06.472.699.631.692.781.100', 'D12.644.400.900.100', 'D12.644.456.925.100', 'D12.644.548.691.692.781.100', 'D12.776.631.650.937.100'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D04.210.500.365.415.414', 'D04.210.500.578.502.497', 'D06.472.040.502.497', 'D06.472.334.851.437.996'], ['E01.370.225.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Homocysteine and lipid metabolism in atherogenesis: effect of the homocysteine thiolactonyl derivatives, thioretinaco and thioretinamide. | In order to study the relation of homocysteine and lipid metabolism to atherogenesis, rabbits were fed a synthetic atherogenic diet and treated with parenteral thioretinaco (N-homocysteine thiolactonyl retinamido cobalamin), thioretinamide (N-homocysteine thiolactonyl retinamide) or homocysteine thiolactone hydrochlori... | ['Animals', 'Arteriosclerosis', 'Diet, Atherogenic', 'Homocysteine', 'Lipids', 'Muscle, Smooth, Vascular', 'Rabbits', 'Tretinoin', 'Vitamin B 12'] | 2,242,097 | [['B01.050'], ['C14.907.137.126'], ['G07.203.650.240.242'], ['D02.886.030.498', 'D12.125.166.498'], ['D10'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['B01.050.150.900.649.313.968.700'], ['D02.455.326.271.665.202.495.818.500', 'D02.455.426.392.368.367.379.249.700.860.500', 'D02.455.849.131.495.818.800... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cryptococcal meningitis post autologous stem cell transplantation. | Disseminated Cryptococcus disease occurs in patients with defective T-cell immunity. Cryptococcal meningitis following autologous stem cell transplant (SCT) has been described previously in only 1 patient, 4 months post SCT and while off antifungal prophylaxis. We present a unique case of Cryptococcus meningitis pre-en... | ['Adult', 'Amphotericin B', 'Antifungal Agents', 'Fluconazole', 'Flucytosine', 'Humans', 'Immunosuppressive Agents', 'Male', 'Meningitis, Cryptococcal', 'Stem Cell Transplantation', 'Transplantation, Autologous'] | 24,750,320 | [['M01.060.116'], ['D02.540.576.500.500'], ['D27.505.954.122.136'], ['D03.383.129.799.450'], ['D03.383.742.698.421.431'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['C01.150.703.181.500.500', 'C01.150.703.248.290', 'C01.207.198.500.500', 'C10.228.228.198.500.500', 'C10.228.614.300.500'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Revascularization by percutaneous transluminal angioplasty improved abruptly deteriorated ischaemic symptoms in cutaneous polyarteritis nodosa. | We report a patient with cutaneous polyarteritis nodosa, who had a 3-year history of recurrent leg and foot ulcers. Symptoms of ischaemia in the left foot, including severe pain, coldness, paraesthesia and violaceous discoloration, deteriorated abruptly, because of complete occlusion of the left anterior tibial artery.... | ['Angioplasty', 'Arterial Occlusive Diseases', 'Female', 'Humans', 'Ischemia', 'Leg Ulcer', 'Middle Aged', 'Polyarteritis Nodosa', 'Radiography', 'Skin', 'Tibial Arteries'] | 21,463,351 | [['E02.148.050', 'E04.100.814.529.124', 'E04.502.382.124', 'E05.157.016'], ['C14.907.137'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.513'], ['C17.800.893.592'], ['M01.060.116.630'], ['C14.907.940.090.720', 'C14.907.940.897.500', 'C17.800.862.625'], ['E01.370.350.700'], ['A17.815'], ['A07.015.114.895']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Left atrial myxoma associated with severe congestive heart failure, pulmonary hypertension, and multiple organ insufficiency. | We have experienced a case of left atrial (LA) myxoma with rapid progression of congestive heart failure and ensuing multiple organ insufficiency. After the tumor excision, the hemodynamic derangement was totally corrected and the patient dramatically recovered from kidney, liver, and lung insufficiency. Specifically, ... | ['Adult', 'Alprostadil', 'Antihypertensive Agents', 'Disease Progression', 'Female', 'Heart Atria', 'Heart Failure', 'Heart Neoplasms', 'Humans', 'Hypertension, Pulmonary', 'Multiple Organ Failure', 'Myxoma', 'Vasodilator Agents'] | 8,627,990 | [['M01.060.116'], ['D10.251.355.255.550.250.100', 'D10.251.355.325.050', 'D23.469.050.175.725.250.100'], ['D27.505.954.411.162'], ['C23.550.291.656'], ['A07.541.358'], ['C14.280.434'], ['C04.588.894.309', 'C14.280.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['C23.550.835.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Compositions and residual properties of petroleum hydrocarbon in contaminated soil of the oilfields]. | The aims of this study were to determine the compositions and residual properties of petroleum hydrocarbon in soil, as well as to identify the source and weathering degree of the pollution. A total of 5 producing wells in Gudao and Hekou oil producing region of Shengli oilfields were analyzed. More than 50 individual t... | ['Alkanes', 'Gas Chromatography-Mass Spectrometry', 'Hydrocarbons', 'Petroleum', 'Polycyclic Aromatic Hydrocarbons', 'Soil', 'Soil Pollutants', 'Solvents'] | 24,720,209 | [['D02.455.326.146'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D02.455'], ['D20.345.630', 'N06.230.132.258.630'], ['D02.455.426.559.847', 'D04.615'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D27.888.284.756'], ['D27.720.844']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Injection of intrathecal normal saline in decreasing postdural puncture headache. | PURPOSE: Postdural puncture headache (PDPH) is the most common and still unresolved postoperative complication of spinal anesthesia. Although there are several positive results of intrathecal saline injection for the treatment of PDPH and prophylaxis after accidental dural puncture, the effect of deliberate intrathecal... | ['Adolescent', 'Adult', 'Anesthesia, Spinal', 'Anesthetics, Local', 'Bupivacaine', 'Cesarean Section', 'Female', 'Humans', 'Incidence', 'Injections, Spinal', 'Post-Dural Puncture Headache', 'Pregnancy', 'Sodium Chloride', 'Young Adult'] | 23,903,901 | [['M01.060.057'], ['M01.060.116'], ['E03.155.086.331'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['D02.065.199.239', 'D02.092.146.113.239'], ['E04.520.252.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Regenerative potential of human dental pulp stem cells in the treatment of stress urinary incontinence: In vitro and in vivo study. | OBJECTIVES: To evaluate the regenerative potential of human dental pulp stem cells (hDPSCs) in an animal model of stress urinary incontinence (SUI). SUI, an involuntary leakage of urine, is due to physical stress involving an increase in bladder pressure and a damage of external urethral sphincter affecting muscles and... | ['Animals', 'Cell Differentiation', 'Dental Pulp', 'Disease Models, Animal', 'Female', 'Humans', 'Rats', 'Stem Cells', 'Urethra', 'Urinary Incontinence, Stress'] | 31,553,127 | [['B01.050'], ['G04.152'], ['A14.549.167.900.260'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.700'], ['A11.872'], ['A05.360.444.492.726', 'A05.810.876'], ['C12.777.934.852.249', 'C13.351.968.934.814.500', 'C23.888.942.343.800.50... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The diagnostic value of water immersion skin wrinkling and Neuropads in small fiber neuropathy. | OBJECTIVE: To investigate the diagnostic yield of two simple tests for small fiber neuropathy (SFN): Neuropads® and water immersion skin wrinkling (WISW).METHODS: We studied 35 patients clinically diagnosed with SFN and 61 age- and sex-matched healthy controls. Wrinkling was judged as absent (abnormal), or present (nor... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Immersion', 'Male', 'Middle Aged', 'Neurologic Examination', 'Polyneuropathies', 'Sensitivity and Specificity', 'Water'] | 22,475,982 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.466'], ['M01.060.116.630'], ['E01.370.376.550', 'E01.370.600.550'], ['C10.668.829.800'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Neuronal heparan sulfates promote amyloid pathology by modulating brain amyloid-â clearance and aggregation in Alzheimer's disease. | Accumulation of amyloid-â (Aâ) peptide in the brain is the first critical step in the pathogenesis of Alzheimer's disease (AD). Studies in humans suggest that Aâ clearance from the brain is frequently impaired in late-onset AD. Aâ accumulation leads to the formation of Aâ aggregates, which injure synapses and contribut... | ['Aged, 80 and over', 'Alzheimer Disease', 'Amyloid', 'Amyloid beta-Peptides', 'Animals', 'Disease Models, Animal', 'Heparitin Sulfate', 'Hippocampus', 'Humans', 'Inflammation', 'Mice', 'Neurons', 'Protein Aggregation, Pathological'] | 27,030,596 | [['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D05.500.049', 'D12.776.049'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D09.698.373.425'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.50... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Six year audit of cardiac arrests and medical emergency team calls in an Australian outer metropolitan teaching hospital. | PROBLEM: In-hospital cardiac arrest often represents failure of optimal clinical care. The use of medical emergency teams to prevent such events is controversial. In-hospital cardiac arrests have been reduced in several single centre historical control studies, but the only randomised prospective study showed no such b... | ['Emergency Medicine', 'Emergency Service, Hospital', 'Emergency Treatment', 'Heart Arrest', 'Hospitals, Teaching', 'Hospitals, Urban', 'Humans', 'Medical Audit', 'Medical Staff, Hospital', 'Patient Care Team', 'Prospective Studies', 'Quality of Health Care', 'Staff Development', 'Victoria'] | 18,048,504 | [['H02.403.250'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E02.365'], ['C14.280.383'], ['N02.278.020.300', 'N02.278.421.639'], ['N02.278.421.660'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.250.500', 'N05.700.175.500'], ['M01.526.485.630.490', 'M01.526.485.740.42... | ['Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Fecal occult blood testing and the incidence of colorectal cancer. | OBJECTIVE: The objective of this abstract is to demonstrate by life table methodology a significant reduction in the mean annual incidence rate of colorectal cancer in randomized groups with annual or biennial screening for fecal occult blood, as compared with the annual incidence rate in the control group.BACKGROUND: ... | ['Aged', 'Aged, 80 and over', 'Colonic Neoplasms', 'Female', 'Humans', 'Incidence', 'Life Tables', 'Male', 'Mass Screening', 'Middle Aged', 'Minnesota', 'Occult Blood'] | 15,305,783 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', '... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Tick-borne lymphadenopathy (TIBOLA) acquired in Southwestern Germany. | BACKGROUND: Tick-borne lymphadenopathy (TIBOLA) was first described in 1997 in a patient in France. The causative agent, Rickettsia slovaca, is transmitted by Dermacentor ticks.CASE PRESENTATION: In southwestern Germany we encountered a patient with a tick bite at the dorsal scalp that resulted in an eschar and nuchal ... | ['Aged', 'Animals', 'Antibodies, Bacterial', 'Arachnid Vectors', 'Dermacentor', 'Female', 'Germany', 'Humans', 'Lymphatic Diseases', 'Rickettsia', 'Rickettsia Infections'] | 21,663,601 | [['M01.060.116.100'], ['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['N06.850.335.188.100.100', 'N06.850.520.203.375.100.100'], ['B01.050.500.131.166.132.832.400.200'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.604'], ['B03.660.... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Identification of MOR-Positive B Cell as Possible Innovative Biomarker (Mu Lympho-Marker) for Chronic Pain Diagnosis in Patients with Fibromyalgia and Osteoarthritis Diseases. | Fibromyalgia (FM) diagnosis follows the American College of Rheumatology (ACR) criteria, based on clinical evaluation and written questionnaires without any objective diagnostic tool. The lack of specific biomarkers is a tragic aspect for FM and chronic pain diseases in general. Interestingly, the endogenous opioid sys... | ['Adolescent', 'Adult', 'Aged', 'B-Lymphocytes', 'Biomarkers', 'Chronic Pain', 'Cross-Sectional Studies', 'Female', 'Fibromyalgia', 'Humans', 'Male', 'Middle Aged', 'Osteoarthritis', 'Pain Management', 'Receptors, Opioid, mu', 'Sensitivity and Specificity', 'Single-Blind Method', 'Young Adult'] | 32,098,316 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D23.101'], ['C23.888.592.612.274'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C05.651.324', 'C05.799.3... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of cholinergic markers in Alzheimer's disease and in a model of cholinergic deficit. | Cognitive deficits in neuropsychiatric disorders, such as Alzheimer's disease (AD), have been closely related to cholinergic deficits. We have compared different markers of cholinergic function to assess the best biomarker of cognitive deficits associated to cholinergic hypoactivity. In post-mortem frontal cortex from ... | ['Acetylcholine', 'Acetylcholinesterase', 'Aged', 'Alzheimer Disease', 'Analysis of Variance', 'Animals', 'Antibodies, Monoclonal', 'Biomarkers', 'Brain', 'Case-Control Studies', 'Disease Models, Animal', 'Female', 'Humans', 'Immunotoxins', 'Male', 'Mental Status Schedule', 'N-Glycosyl Hydrolases', 'Postmortem Changes'... | 15,664,119 | [['D02.092.211.111'], ['D08.811.277.352.100.170.176'], ['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[Detection and characterization of a levansucrase and a sucrase in Pseudomonas syringae pv. phaseolicola]. | Pseudomonas syringae pv. phaseolicola, a plant pathogenic pseudomonad, possesses two sucrose-splitting enzymes, a levansucrase and a sucrase. The levansucrase is found both extracellularly and intracellularly, and enzyme synthesis is independent of the carbon source. In addition to levansucrase, cells grown on sucrose ... | ['Hexosyltransferases', 'Hydrogen-Ion Concentration', 'Pseudomonas', 'Substrate Specificity', 'Sucrase', 'Temperature'] | 3,236,222 | [['D08.811.913.400.450'], ['G02.300'], ['B03.440.400.425.625.625', 'B03.660.250.580.590'], ['G02.111.835'], ['D08.811.277.450.329.738'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Stump sensibility in children with upper limb reduction deficiency. | OBJECTIVES: To compare stump sensibility in children with upper limb reduction deficiency with sensibility of the unaffected arm and hand. In addition, to evaluate the associations between stump sensibility, stump length and activity level.DESIGN: Cross-sectional study.SUBJECTS: Children and young adults aged 6-25 year... | ['Adolescent', 'Adult', 'Amputation Stumps', 'Amputees', 'Child', 'Child, Preschool', 'Cross-Sectional Studies', 'Female', 'Humans', 'Kinesthesis', 'Male', 'Motor Activity', 'Stereognosis', 'Touch', 'Upper Extremity', 'Young Adult'] | 24,036,887 | [['M01.060.057'], ['M01.060.116'], ['A01.378.100'], ['M01.150.100'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.830.816.541.504', 'G11.561.790.541.587'], ['F01.145.632', 'G11.427.410.698'], [... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Children who witness violence, and parent report of children's behavior. | OBJECTIVES: To examine how much distress children report in response to violence that they have witnessed and how this is associated with parental reports of children's behavior.METHODS: As part of a study of in utero exposure to cocaine, children completed the Levonn interview for assessing children's symptoms of dist... | ['Child', 'Child Behavior', 'Cocaine-Related Disorders', 'Female', 'Humans', 'Linear Models', 'Male', 'Mothers', 'Risk Factors', 'Surveys and Questionnaires', 'Urban Population', 'Violence'] | 12,144,371 | [['M01.060.406'], ['F01.145.179'], ['C25.775.300', 'F03.900.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['F01.829.263.500.320.200', '... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Differences in the metabolic status of healthy adults with and without active brown adipose tissue. | BACKGROUND: Previous studies have proven the existence of active brown adipose tissue (BAT) in adults; however, its effect on systematic metabolism remains unclear.AIM: The current study was designed to investigate the differences in the metabolic profiles of healthy adults with and without active BAT using positron em... | ['Adipose Tissue, Brown', 'Adult', 'Blood Glucose', 'Body Composition', 'Energy Metabolism', 'Female', 'Humans', 'Male', 'Reference Values'] | 24,146,327 | [['A10.165.114.322'], ['M01.060.116'], ['D09.947.875.359.448.500'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['G03.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.978.810']] | ['Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Predictors of massive blood transfusion: a Delphi Study to examine the views of experts. | BACKGROUND: Trauma patients requiring massive blood transfusion (MBT) have high morbidity and mortality: early and aggressive use of blood products during immediate resuscitation may improve survival. There is currently a lack of evidence to guide initial identification of these patients which is especially important i... | ['Blood Transfusion', 'Delphi Technique', 'Hemorrhage', 'Humans', 'Resuscitation', 'Risk Assessment', 'Wounds and Injuries'] | 28,320,917 | [['E02.095.135'], ['L01.906.197'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.365.647'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['C26']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Beta-endorphin and endogenous alcohol level of the blood in alcoholic patients]. | Radioimmunoassay was used to measure the blood content of beta-endorphines in patients with chronic alcoholism. The concentration of endogenous ethanol in these patients was determined by gas chromatography. The blood concentration of beta-endorphines was found to be high in patients who showed atypical affective disor... | ['Adult', 'Alcoholism', 'Chromatography, Gas', 'Endorphins', 'Ethanol', 'Humans', 'Male', 'Psychopathology', 'Radioimmunoassay', 'Time Factors', 'beta-Endorphin'] | 6,095,946 | [['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['E05.196.181.349'], ['D12.644.400.575.241', 'D12.776.631.650.575.241'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.096.670'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['G01.910.857'], ['D06.472.699.327.935.239', 'D... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluating subchronic toxicity of fluoxastrobin using earthworms (Eisenia fetida). | Potential toxicity to soil organisms by fluoxastrobin, a new strobilurin-type fungicide has drawn increasing attention. Thus, the present study investigated the subchronic toxicity induced by exposure to several concentrations (0, 0.1, 1.0, and 2.5 mg kg-1) of fluoxastrobin to earthworms on days 7, 14, 21, and 28. Bioc... | ['Animals', 'Catalase', 'DNA Damage', 'Malondialdehyde', 'Oligochaeta', 'Oxidative Stress', 'Soil Pollutants', 'Strobilurins', 'Superoxide Dismutase', 'Toxicity Tests'] | 29,909,323 | [['B01.050'], ['D08.811.682.732.332'], ['G05.200'], ['D02.047.700'], ['B01.050.500.091.657'], ['G03.673', 'G07.775.750'], ['D27.888.284.756'], ['D02.241.081.069.600.575'], ['D08.811.682.881'], ['E05.940']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Pseudotumoral abdominal cysto-steato-necrosis: an unusual etiology]. | We report an unusual case of subcutaneous pseudo-neoplastic focal fat necrosis in a woman with a Mersilen plate placed outside the abdominal wall muscles. To our knowledge, this association has not been previously reported in the radiologic literature. The differential diagnosis using ultrasound and computerized tomogr... | ['Abdominal Muscles', 'Abdominal Neoplasms', 'Aged', 'Diagnosis, Differential', 'Fat Necrosis', 'Female', 'Humans', 'Polyethylene Terephthalates', 'Prostheses and Implants', 'Surgical Mesh', 'Tomography, X-Ray Computed'] | 9,163,960 | [['A02.633.567.050'], ['C04.588.033'], ['M01.060.116.100'], ['E01.171'], ['C23.550.717.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.728.764', 'D25.720.728.764', 'J01.637.051.720.728.764'], ['E07.695'], ['E07.858.708'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810'... | ['Anatomy [A]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
[Textual research on circulated versions of Wen re lun (On epidemic warm diseases) and its related problems]. | The Wen re lun (On Epidemic Warm Diseases), written by Ye Tian-shi, a famous physician of epidemic warm diseases in the Qing dynasty, was originally a teaching record between the tutors and disciples. The book was originally anonymous, and there were two different circulated versions compiled by two different scholars.... | ['China', 'Disease', 'History, 18th Century', 'Textbooks as Topic'] | 19,127,849 | [['Z01.252.474.164'], ['C23.550.288'], ['K01.400.504.875'], ['L01.178.682.192.900', 'L01.178.820.900']] | ['Geographicals [Z]', 'Diseases [C]', 'Humanities [K]', 'Information Science [L]'] | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Apathy and Disinhibition Related to Neuropathology in Amnestic Versus Behavioral Dementias. | OBJECTIVES: Investigating the frequency of apathy and disinhibition in patients clinically diagnosed with dementia of the Alzheimer type (DAT) or behavioral variant frontotemporal dementia (bvFTD) with neuropathology of either Alzheimer disease (AD) or frontotemporal lobar degeneration (FTLD).METHODS: Retrospective dat... | ['Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Apathy', 'Disease Progression', 'Female', 'Frontotemporal Dementia', 'Frontotemporal Lobar Degeneration', 'Humans', 'Inhibition, Psychological', 'Longitudinal Studies', 'Male', 'Retrospective Studies', 'Severity of Illness Index'] | 31,170,813 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['F01.470.137'], ['C23.550.291.656'], ['C10.228.140.380.266.299', 'C10.574.950.300.299', 'C18.452.845.800.300.299', 'F03.615.400.380.299'], ['C10.228.140.380.266', 'C10.574.950.300', 'C18.452.845.800.300', 'F03... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Conformationally restricted hybrid analogues of the hormone 1 alpha,25-dihydroxyvitamin D(3): design, synthesis, and biological evaluation. | Four new conformationally restricted hybrid analogues of the hormone 1 alpha-25-dihydroxyvitamin D(3) (1,25D3) have been synthesized in a convergent manner by combining enantiomerically pure C,D-ring ketones (-)-15 and (-)-17 with racemic 1-hydroxymethyl A-ring phosphine oxide (+/-)-18. Parent hybrid analogue 6, which ... | ['Animals', 'Calcitriol', 'Female', 'Magnetic Resonance Spectroscopy', 'Mass Spectrometry', 'Mice', 'Mice, Inbred C57BL', 'Molecular Conformation'] | 11,425,569 | [['B01.050'], ['D04.210.500.247.222.159.478.387.300', 'D04.210.500.247.808.146.478.387.300', 'D04.210.500.812.768.196.478.387.300', 'D10.570.938.146.478.387.300'], ['E05.196.867.519'], ['E05.196.566'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of Blood Pressure Lowering in Early Ischemic Stroke: Meta-Analysis. | BACKGROUND AND PURPOSE: Elevated blood pressure is common in acute stage of ischemic stroke and the strategy to manage this situation is not well established. We therefore conducted a meta-analysis of randomized controlled trials comparing active blood pressure lowering and control groups in early ischemic stroke.METHO... | ['Antihypertensive Agents', 'Blood Pressure', 'Brain Ischemia', 'Humans', 'Hypertension', 'Randomized Controlled Trials as Topic', 'Stroke', 'Treatment Outcome'] | 26,022,636 | [['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C10.228.140.300.150', 'C14.907.253.092'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365.500'], ['C10.228.140.300.775', 'C14.907.253.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Metal-free C-N- and N-N-bond formation: synthesis of 1,2,3-triazoles from ketones, N-tosylhydrazines, and amines in one pot. | A novel synthetic approach toward 1,4-disubstituted 1,2,3-triazoles by C-N- and N-N-bond formation has been established under transition-metal-free conditions. Complete control of the regioselectivity was successfully achieved. Commercially available anilines, ketones, and N-tosylhydrazine were treated with molecular i... | ['Amines', 'Catalysis', 'Ketones', 'Metals', 'Molecular Structure', 'Tosyl Compounds', 'Triazoles'] | 25,354,088 | [['D02.092'], ['G02.130'], ['D02.522'], ['D01.552'], ['G02.111.570', 'G02.466'], ['D02.455.426.559.389.832.661', 'D02.886.590.887'], ['D03.383.129.799']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Maximal intestinal absorption of digoxin, and its relation to steady state plasma concentration. | In a group of 8 volunteers, peak plasma digoxin concentrations and areas under 80-hour plasma concentration curves were significantly greater after 1 mg digoxin in paediatric elixir than after 4 0,25 mg tablets. Mean cumulative urinary excretion of digoxin over 12 days was 46.4 per cent after tablets, 53.6 per cent aft... | ['Adult', 'Clinical Trials as Topic', 'Digoxin', 'Humans', 'Injections, Intravenous', 'Intestinal Absorption', 'Solutions', 'Tablets', 'Time Factors'] | 1,091,283 | [['M01.060.116'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D04.210.500.155.580.130.500.436', 'D04.210.500.155.580.130.688', 'D09.408.180.261.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['G03.015.500.374.500', 'G03.787.02... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Assembly of chromatin fibers into metaphase chromosomes analyzed by transmission electron microscopy and scanning electron microscopy. | The higher-order assembly of the approximately 30 nm chromatin fibers into the characteristic morphology of HeLa mitotic chromosomes was investigated by electron microscopy. Transmission electron microscopy (TEM) of serial sections was applied to view the distribution of the DNA-histone-nonhistone fibers through the ch... | ['Calcium', 'Chromatin', 'Chromosomal Proteins, Non-Histone', 'DNA, Neoplasm', 'HeLa Cells', 'Humans', 'Magnesium', 'Metaphase', 'Microscopy, Electron', 'Microscopy, Electron, Scanning'] | 3,955,172 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D12.776.660.235', 'D12.776.664.235'], ['D13.444.308.425'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.55... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Youth Parasympathetic Functioning Moderates Relations between Cumulative Family Risk and Internalizing Behaviors. | Problematic family functioning places young adolescents at risk for internalizing behaviors. However, not all adolescents who experience family risk develop internalizing behaviors during early adolescence. Informed by a cumulative risk perspective, the current study examined whether associations between cumulative fam... | ['Adaptation, Psychological', 'Adolescent', 'Adolescent Behavior', 'Defense Mechanisms', 'Depression', 'Family Relations', 'Female', 'Humans', 'Internal-External Control', 'Male', 'Parasympathetic Nervous System', 'Stress, Psychological'] | 31,606,829 | [['F01.058'], ['M01.060.057'], ['F01.145.022'], ['F01.393'], ['F01.145.126.350'], ['F01.829.263.370', 'I01.880.853.150.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['A08.800.050.600'], ['F01.145.126.990', 'F02.830.900']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Interactions between Mycobacterium leprae and simian immunodeficiency virus (SIV) in rhesus monkeys. | Groups of rhesus monkeys were inoculated with: 1) simian immunodeficiency virus (SIV)B670 alone; 2) Mycobacterium leprae alone; 3) SIV plus M. leprae on the same day; and 4) M. leprae 2 weeks after SIV. Animals were monitored at intervals for virus loads, antibody responses to M. leprae glycolipid antigens and to SIV G... | ['Animals', 'Antibodies, Viral', 'CD4-CD8 Ratio', 'CD4-Positive T-Lymphocytes', 'CD8-Positive T-Lymphocytes', 'Disease Progression', 'HIV Envelope Protein gp120', 'Immunoglobulin G', 'Leprosy', 'Macaca mulatta', 'Membrane Glycoproteins', 'Mycobacterium leprae', 'RNA, Viral', 'Reverse Transcriptase Polymerase Chain Reac... | 11,085,588 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['E01.370.225.500.195.107.595.500.150.160', 'E01.370.225.625.107.595.500.150.160', 'E05.200.500.195.107.595.500.150.160', 'E05.200.625.107.595.500.150.160', 'E05.242.195.107.595.500.150.160', 'G04.140.107.595.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Quantification of Right Ventricular Electromechanical Dyssynchrony in Relation to Right Ventricular Function and Clinical Outcomes in Children with Repaired Tetralogy of Fallot. | BACKGROUND: Electromechanical dyssynchrony occurs ubiquitously following tetralogy of Fallot (TOF) repair, manifesting electrically as a wide QRS duration and mechanically as a right-sided septal/apical flash. Early septal activation and prestretch of the right ventricular (RV) basal lateral wall followed by its postsy... | ['Adolescent', 'Child', 'Child, Preschool', 'Cross-Sectional Studies', 'Echocardiography, Doppler', 'Electrocardiography', 'Exercise Tolerance', 'Female', 'Follow-Up Studies', 'Humans', 'Magnetic Resonance Imaging, Cine', 'Male', 'Retrospective Studies', 'Severity of Illness Index', 'Statistics, Nonparametric', 'Stroke... | 29,976,349 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['G11.427.680.270'], ['E05.318.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pharmacodynamics and pharmacokinetics of high-dose sufentanil in infants and children undergoing cardiac surgery. | The pharmacodynamic and pharmacokinetic profiles of high-dose sufentanil (15 micrograms/kg) and oxygen were determined in 20 infants and children undergoing repair of congenital heart defects. Sufentanil provided marked hemodynamic stability after an infusion and during the stress periods of incision and sternotomy. Tw... | ['Anesthesia, Intravenous', 'Anesthetics', 'Child, Preschool', 'Fentanyl', 'Heart Defects, Congenital', 'Humans', 'Infant', 'Stress, Physiological', 'Sufentanil'] | 2,950,809 | [['E03.155.308'], ['D27.505.696.277.100', 'D27.505.954.427.210.100'], ['M01.060.406.448'], ['D03.383.621.265'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G07.775'], ['D03.383.621.265.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Results of a second survey to assess the reproductive status of female Asian and African elephants in North America. | Surveys are being conducted to monitor the reproductive health of elephants managed by the TAG/SSP. This study summarizes results of a 2005 survey and compares data to one conducted in 2002. Surveys were returned for 100% and 79.0% of Asian and African elephants, respectively. Of those, 79.3% of Asian and 92.1% of Afri... | ['Aging', 'Animals', 'Animals, Zoo', 'Data Collection', 'Elephants', 'Estrous Cycle', 'Female', 'North America'] | 20,391,465 | [['G07.345.124'], ['B01.050'], ['B01.050.050.448'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['B01.050.150.900.649.833.249'], ['G08.686.195'], ['Z01.107.567']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Towards a therapeutic inhibition of dystrophin exon 23 splicing in mdx mouse muscle induced by antisense oligoribonucleotides (splicomers): target sequence optimisation using oligonucleotide arrays. | BACKGROUND: The activity of synthetic antisense oligonucleotides (splicomers) designed to block pre-mRNA splicing at specific exons has been demonstrated in a number of model systems, including constitutively spliced exons in mouse dystrophin RNA. Splicomer reagents directed to Duchenne muscular dystrophy (DMD) RNAs mi... | ['Alleles', 'Alternative Splicing', 'Animals', 'Base Sequence', 'Blotting, Western', 'DNA', 'Dose-Response Relationship, Drug', 'Dystrophin', 'Exons', 'Frameshift Mutation', 'Genetic Therapy', 'Immunohistochemistry', 'Introns', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred mdx', 'Molecular Sequence Data', 'Muscles', 'Mus... | 15,386,737 | [['G05.360.340.024.340.030'], ['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D13.444.308'], ['G07.690.773.875', 'G07.690.936.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Potent, highly selective, and non-thiol inhibitors of protein geranylgeranyltransferase-I. | The design, synthesis, and biological evaluation of a family of peptidomimetic inhibitors of protein geranylgeranyltransferase-I (PGGTase-I) are reported. The inhibitors are based on the C-terminal CAAL sequence of many geranylgeranylated proteins. Using 2-aryl-4-aminobenzoic acid derivatives as mimetics for the centra... | ['3T3 Cells', 'Alkyl and Aryl Transferases', 'Animals', 'Drug Design', 'Enzyme Inhibitors', 'GTP-Binding Proteins', 'Imidazoles', 'Leucine', 'Mice', 'Molecular Mimicry', 'Protein Prenylation', 'Structure-Activity Relationship', 'rap GTP-Binding Proteins'] | 10,212,118 | [['A11.251.210.100', 'A11.329.228.100'], ['D08.811.913.225'], ['B01.050'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['D27.505.519.389'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['D03.383.129.308'], ['D12.125.070.637', 'D12.125.142.441'], ['B01.050.150.900.649.313.992.635.505.500'], ['G... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Multiple, annular, erythematous lesions of the oral mucosa. | Benign migratory stomatitis is a relatively rare entity, but because of its benign nature and clinical characteristics, it should be easily recognized by the general practitioner. Biopsy is usually not indicated and treatment consists of reassuring the patient that the lesions are benign even though they may disappear,... | ['Diagnosis, Differential', 'Erythema', 'Glossitis, Benign Migratory', 'Humans', 'Male', 'Middle Aged', 'Stomatitis'] | 3,422,674 | [['E01.171'], ['C17.800.229', 'C23.888.885.328'], ['C07.465.910.363.447'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C07.465.864']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Qualitative analysis of some carboxylic acids by ion-exclusion chromatography with atmospheric pressure chemical ionization mass spectrometric detection. | A simple, selective and sensitive method for the determination of carboxylic acids has been developed. A mixture of formic, acetic, propionic, valeric, isovaleric, isobutyric, and isocaproic acids has been separated on a polymethacrylate-based weak acidic cation-exchange resin (TSK gel OA pak-A) based on an ion-exclusi... | ['Atmospheric Pressure', 'Carboxylic Acids', 'Chromatography, Ion Exchange', 'Electrochemistry', 'Mass Spectrometry', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 12,108,651 | [['G16.500.750.274', 'N06.230.300.100.185'], ['D02.241'], ['E05.196.181.400.383'], ['H01.181.529.307'], ['E05.196.566'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800'... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
The failure to separate human X-and Y-spermatozoa by the millipore filtration technique. | Millipore filtration of motile human spermatozoa with the use of a pore size of 5 micrometer without applying high or low pressure results in a small but statistically significant increase of Y-spermatozoa in the filtrate. Immobilized spermatozoa do not pass through the membrane. | ['Female', 'Humans', 'Male', 'Micropore Filters', 'Pressure', 'Sex Preselection', 'Spermatozoa', 'X Chromosome', 'Y Chromosome'] | 564,404 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.454.403', 'E07.560'], ['G01.374.715'], ['E05.393.420.890'], ['A05.360.490.890', 'A11.497.760'], ['A11.284.187.865.982', 'G05.360.162.865.982'], ['A11.284.187.865.983', 'G05.360.162.865.983']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tobacco habits in nocturnal frontal lobe epilepsy. | The beneficial effect of nicotine has been reported in autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) patients, but not tested in sporadic cases. Recently, a nicotine defect in the arousal pathway has been hypothesized even in sporadic NFLE patients and their relatives. This case-control family study was d... | ['Adult', 'Aged', 'Case-Control Studies', 'Electroencephalography', 'Epilepsy, Frontal Lobe', 'Female', 'Habits', 'Humans', 'Male', 'Middle Aged', 'Mutation', 'Polysomnography', 'Receptors, Nicotinic', 'Retrospective Studies', 'Tobacco Use Disorder', 'Video Recording', 'Young Adult'] | 23,246,147 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.360.270', 'C10.228.140.490.493.188'], ['F01.145.466'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G05.365.590'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Orthodontic side-effects of mandibular advancement devices during treatment of snoring and sleep apnoea. | The aims of this study were to investigate possible orthodontic side-effects following the use of mandibular advancement devices (MAD) in adults with snoring and sleep apnoea. A second objective was to analyse the effect of the appliance design. Seventy-five patients treated with MAD and 17 reference patients were stud... | ['Acrylic Resins', 'Adult', 'Aged', 'Centric Relation', 'Chi-Square Distribution', 'Dental Occlusion, Traumatic', 'Female', 'Humans', 'Male', 'Mandibular Advancement', 'Middle Aged', 'Occlusal Splints', 'Orthodontic Appliance Design', 'Silicone Elastomers', 'Sleep Apnea, Obstructive', 'Snoring', 'Statistics, Nonparamet... | 11,398,551 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['M01.060.116'], ['M01.060.116.100'], ['E06.520.200'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C07.793.494.293'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.545.500', 'E06.... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Fusion pore diameter regulation by cations modulating local membrane anisotropy. | The fusion pore is an aqueous channel that is formed upon the fusion of the vesicle membrane with the plasma membrane. Once the pore is open, it may close again (transient fusion) or widen completely (full fusion) to permit vesicle cargo discharge. While repetitive transient fusion pore openings of the vesicle with the... | ['Cations', 'Cell Fusion', 'Cell Membrane', 'Models, Theoretical'] | 22,489,211 | [['D01.248.497.300'], ['E05.242.307', 'G04.155'], ['A11.284.149'], ['E05.599']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neutron reflectivity studies of single lipid bilayers supported on planar substrates. | Neutron reflectivity was used to probe the structure of single phosphatidylcholine (PC) lipid bilayers adsorbed onto a planar silicon surface in an aqueous environment. Fluctuations in the neutron scattering length density profiles perpendicular to the silicon/water interface were determined for different lipids as a f... | ['1,2-Dipalmitoylphosphatidylcholine', 'Deuterium Oxide', 'Lipid Bilayers', 'Molecular Conformation', 'Molecular Structure', 'Neutrons', 'Phosphatidylcholines', 'Scattering, Radiation', 'Silicon', 'Water'] | 9,031,513 | [['D10.570.755.375.760.400.800.224'], ['D01.045.250.875.200', 'D01.248.497.158.459.650.200', 'D01.268.406.500.250', 'D01.362.340.500.250'], ['D10.570.510', 'J01.637.087.500.510'], ['G02.111.570.820'], ['G02.111.570', 'G02.466'], ['G01.249.660.250'], ['D10.570.755.375.760.400.800'], ['E05.196.822', 'G01.867'], ['D01.268... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
RNAi blocks DYT1 mutant torsinA inclusions in neurons. | Early onset generalized dystonia is a dominantly inherited movement disorder caused by neuronal dysfunction without an apparent loss of neurons. The same single mutation (GAG deletion) causes most cases and results in loss of a glutamic acid (E) in the carboxy terminal region of torsinA (Delta302/303). To model the neu... | ['Animals', 'Cells, Cultured', 'Cloning, Molecular', 'Ganglia, Spinal', 'Gene Deletion', 'Genes, gag', 'Genetic Vectors', 'Glutamic Acid', 'Humans', 'Lentivirus', 'Molecular Chaperones', 'Neurons', 'Oligonucleotides', 'RNA Interference', 'RNA, Small Interfering', 'Rats', 'Rats, Sprague-Dawley'] | 16,332,410 | [['B01.050'], ['A11.251'], ['E05.393.220'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.360.340.024.340.364.875.258', 'G05.360.340.358.024.875.258', 'G05.360.340.358.840.500.258'], ['G05.360.337'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Decreases in human dendritic cell-dependent T(H)2-like responses after acute in vivo IgE neutralization. | BACKGROUND: Dendritic cells (DCs) and other professional antigen-presenting cells express a variant of the high-affinity IgE receptor known as alphagamma(2), which, on the basis of in vitro findings, has long been implicated to function in facilitating allergen uptake and presentation to T(H) cells.OBJECTIVES: To use o... | ['Adolescent', 'Adult', 'Allergens', 'Animals', 'Antibodies, Anti-Idiotypic', 'Antibodies, Monoclonal', 'Antibodies, Monoclonal, Humanized', 'Antibodies, Neutralizing', 'Antigen Presentation', 'CD4-Positive T-Lymphocytes', 'Cats', 'Coculture Techniques', 'Cytokines', 'Dendritic Cells', 'Double-Blind Method', 'Humans', ... | 20,132,969 | [['M01.060.057'], ['M01.060.116'], ['D23.050.063'], ['B01.050'], ['D12.776.124.486.485.114.071', 'D12.776.124.790.651.114.071', 'D12.776.377.715.548.114.071'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Causes of initial remission induction failure in patients with acute myeloid leukemia and myelodysplastic syndromes. | We analyzed 144 of 475 previously untreated patients with acute myeloid leukemia (AML, n = 87) and 'high-risk' myelodysplastic syndromes (MDS, n = 57) who failed to achieve a complete remission with fludarabine- and high-dose cytarabine-containing regimens between 1991 and 1994. The AML and MDS groups were comparable w... | ['Acute Disease', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Antineoplastic Agents', 'Antineoplastic Combined Chemotherapy Protocols', 'Cause of Death', 'Cytarabine', 'Drug Resistance, Neoplasm', 'Female', 'Hemorrhage', 'Humans', 'Leukemia, Myeloid', 'Male', 'Middle Aged', 'Myelodysplastic Syndromes', 'Patie... | 8,618,434 | [['C23.550.291.125'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], [... | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inadequate mass-casualty knowledge base adversely affects treatment decisions by trauma care providers: Survey on hospital response following a terrorist bombing. | Healthcare professionals require a unique knowledge base to function effectively during a hospital's response to a mass-casualty incident (MCI). A survey of 128 physicians, nurses, and emergency medical technicians involved in trauma care was conducted to assess their knowledge base and how it affected their decision-m... | ['Blast Injuries', 'Decision Making', 'Disaster Planning', 'Education, Medical', 'Health Care Surveys', 'Health Personnel', 'Humans', 'Mass Casualty Incidents', 'Terrorism', 'Wounds and Injuries'] | 19,806,559 | [['C26.120.126'], ['F02.463.785.373'], ['N06.230.100.035'], ['I02.358.399'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.198.240.856.800.537', 'I01.880.735.900.800.575'... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Effect of vitrification on promoter methylation and the expression of pluripotency and differentiation genes in mouse blastocysts. | The present study was designed to determine the effects of vitrification on promoter methylation and the expression levels of pluripotency and differentiation genes in mouse blastocysts. Promoter region CpG methylation patterns and the expression levels of octamer-binding transcription factor (Oct4), Nanog homeobox (Na... | ['Animals', 'Basic Helix-Loop-Helix Transcription Factors', 'Blastocyst', 'CDX2 Transcription Factor', 'Cell Differentiation', 'Cryopreservation', 'DNA Methylation', 'Gene Expression Regulation, Developmental', 'Heating', 'Homeodomain Proteins', 'Mice', 'Nanog Homeobox Protein', 'Octamer Transcription Factor-3', 'Promo... | 22,618,890 | [['B01.050'], ['D12.776.260.103', 'D12.776.930.125'], ['A16.254.500'], ['D12.776.260.400.140', 'D12.776.660.201', 'D12.776.930.146'], ['G04.152'], ['E01.370.225.500.620.760.160', 'E01.370.225.750.600.760.160', 'E02.792.156', 'E05.200.500.620.760.160', 'E05.200.750.600.760.160', 'E05.760.156'], ['G02.111.035.538.161', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The effects of alcohol on the emotional displays of Whites in interracial groups. | Discomfort during interracial interactions is common among Whites in the U.S. and is linked to avoidance of interracial encounters. While the negative consequences of interracial discomfort are well-documented, understanding of its causes is still incomplete. Alcohol consumption has been shown to decrease negative emot... | ['Adult', 'Alcohol Drinking', 'Emotions', 'European Continental Ancestry Group', 'Facial Expression', 'Female', 'Group Processes', 'Humans', 'Interpersonal Relations', 'Male', 'Racism', 'Random Allocation', 'Social Behavior', 'United States', 'Verbal Behavior', 'Young Adult'] | 23,356,562 | [['M01.060.116'], ['F01.145.317.269'], ['F01.470'], ['M01.686.508.400'], ['E01.370.600.225', 'F01.145.209.530.385'], ['F01.829.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F01.145.813.550.500', 'F01.145.813.629.625', 'F01.829.595.500', 'I01.880.735.820.500.500'], ['E05.318.370.700', 'E05.5... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Effect of myriocin on plasma sphingolipid metabolism and atherosclerosis in apoE-deficient mice. | Sphingolipids play a very important role in cell membrane formation, signal transduction, and plasma lipoprotein metabolism, all of which may well have an impact on the development of atherosclerosis. To investigate the relationship between sphingolipid metabolism and atherosclerosis, we utilized myriocin to inhibit mo... | ['Acyltransferases', 'Animal Feed', 'Animals', 'Aorta', 'Apolipoproteins E', 'Arteriosclerosis', 'Ceramides', 'Cholesterol', 'Fatty Acids, Monounsaturated', 'Immunosuppressive Agents', 'Lipid Metabolism', 'Lipids', 'Lipoproteins', 'Lysophospholipids', 'Mass Spectrometry', 'Mice', 'Mice, Knockout', 'Phosphatidylcholines... | 15,590,644 | [['D08.811.913.050'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['A07.015.114.056'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['C14.907.137.126'], ['D02.065.313', 'D09.400.410.420.525.200', 'D10.390.470.675.200', 'D10.570.877.360.612.200'], ['D04.210.500.247.222.284', 'D04.210.5... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Transoral vertebroplasty for a C2 aneurysmal bone cyst. | BACKGROUND CONTEXT: Aneurysmal bone cysts at the cervical spine represent a real challenge both diagnostically and therapeutically, especially in young patients.PURPOSE: We present an unusual case of a C2 aneurysmal bone cyst expanding in the entire vertebral body in a girl successfully treated with a transoral vertebr... | ['Adolescent', 'Bone Cysts, Aneurysmal', 'Cervical Vertebrae', 'Female', 'Fluoroscopy', 'Humans', 'Magnetic Resonance Imaging', 'Mouth', 'Natural Orifice Endoscopic Surgery', 'Surgery, Computer-Assisted', 'Tomography, X-Ray Computed', 'Vertebroplasty'] | 26,961,198 | [['M01.060.057'], ['C04.182.089.265', 'C05.116.070.265'], ['A02.835.232.834.151'], ['E01.370.350.700.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A01.456.505.631', 'A03.556.500', 'A14.549'], ['E01.370.388.250.630', 'E04.502.250.630'], ['E04.749'], ['E01.370.350.350.810', 'E01.370.3... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Application of 2,4-bis(halomethyl)quinoline: synthesis and biological activities of 2,4-bis(benzofuran-2-yl)- and 2,4-bis(aroxymethyl)quinolines. | In the present investigation, the synthesis of a new type of halomethylquinoline building block, i.e., ethyl 4-(bromomethyl)-2-(chloromethyl)quinoline-3-carboxylate, and its synthetic applications in the reaction with salicylaldehydes or phenols to make a range of structurally novel and intriguing 2,4-bis(benzofuran-2-... | ['Anti-Bacterial Agents', 'Bacteria', 'Chemistry Techniques, Synthetic', 'Microbial Sensitivity Tests', 'Molecular Structure', 'Quinolines', 'Structure-Activity Relationship'] | 30,895,448 | [['D27.505.954.122.085'], ['B03'], ['E05.197', 'J01.897.836.249'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G02.111.570', 'G02.466'], ['D03.633.100.810'], ['G02.111.830', 'G07.690.773.997']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Comparison of the efficacy of ribavirin plus peginterferon alfa-2b for chronic hepatitis C infection in patients with and without coagulation disorders. | Many patients with coagulation disorders are infected with hepatitis C virus (HCV) that advances to end stage liver disease, resulting in an increased number of deaths. The efficacy of ribavirin and peginterferon combination therapy for chronic HCV infection in patients with coagulation disorders has not been clarified... | ['Adult', 'Aged', 'Antiviral Agents', 'Blood Coagulation Disorders', 'Drug Therapy, Combination', 'Female', 'Hepatitis C, Chronic', 'Humans', 'Interferon alpha-2', 'Interferon-alpha', 'Male', 'Middle Aged', 'Polyethylene Glycols', 'Recombinant Proteins', 'Ribavirin', 'Treatment Outcome', 'Young Adult'] | 23,160,930 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.388'], ['C15.378.100'], ['E02.319.310'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.705.440.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890.250.500', 'D12.776.467... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Localization of corazonin in the nervous system of the cockroach Periplaneta americana. | Antisera raised to the cardioactive peptide corazonin were used to localize immunoreactive cells in the nervous system of the American cockroach. Sera obtained after the seventh booster injection were sufficiently specific to be used for immunocytology. They recognized a subset of 10 lateral neurosecretory cells in the... | ['Amino Acid Sequence', 'Animals', 'Chromatography, High Pressure Liquid', 'Enzyme-Linked Immunosorbent Assay', 'Immunohistochemistry', 'Insect Proteins', 'Molecular Sequence Data', 'Nervous System', 'Neurons', 'Neuropeptides', 'Neurosecretory Systems', 'Periplaneta', 'Tissue Distribution'] | 8,242,711 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.196.181.400.300'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
The first case of primary metacarpal V restoration with titanium mesh and cancellous bone graft. | Any references of use of the titanium mesh in hand reconstruction could not be found. A case of primary metacarpal reconstruction after severe hand trauma with a help of cage made of titanium mesh and cancellous iliac bone graft is presented. | ['Adult', 'Amputation, Traumatic', 'Bone Regeneration', 'Bone Transplantation', 'Fractures, Bone', 'Hand Injuries', 'Humans', 'Male', 'Metacarpal Bones', 'Radiography', 'Reconstructive Surgical Procedures', 'Surgical Mesh', 'Titanium'] | 17,113,527 | [['M01.060.116'], ['C26.062'], ['G11.427.213.140', 'G16.762.150.150'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['C26.404'], ['C26.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.087.319.550'], ['E01.370.350.700'], ['E04.680'], ['E07.858.708'], ['D01.268.557.800', 'D01.268.956.87... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Hemoglobin level in older adults and the association with nutritional status and use of health services: the Bambu? Project]. | This study aimed to describe the prevalence of anemia and to evaluate the association between hemoglobin (Hb) level and indicators of nutritional status and health services utilization in an elderly population (? 60 years). Of the 1,742 older adults in the baseline of the Bambu? cohort, 1,441 (82.7%) were included. The... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Anemia', 'Biomarkers', 'Body Mass Index', 'Brazil', 'Cohort Studies', 'Female', 'Health Services Accessibility', 'Health Services for the Aged', 'Hemoglobin A', 'Humans', 'Male', 'Middle Aged', 'Nutritional Status', 'Prevalence', 'Serum Albumin', 'Socioeconomic Factors'] | 23,147,950 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C15.378.071'], ['D23.101'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['Z01.107.757.176'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N04.590... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Epididymal sperm retrieval by epididymal micropuncture combined with intracytoplasmic sperm injection: difference between acquired and congenital irreparable obstructive azoospermia. | To evaluate the differences in fertilization and pregnancy rates following intracytoplasmic sperm injection (ICSI) of retrieved epididymal sperm between congenital (group 1) and acquired (group 2) unreconstructable obstructive azoospermic patients, we compared the outcome of the ICSI procedure between these two groups.... | ['Adult', 'Case-Control Studies', 'Cytoplasm', 'Epididymis', 'Female', 'Fertilization in Vitro', 'Humans', 'Male', 'Microinjections', 'Oligospermia', 'Pregnancy', 'Punctures', 'Sperm Count', 'Sperm Motility', 'Spermatozoa'] | 9,188,139 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A11.284.430.214'], ['A05.360.444.371'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.690', 'E05.591.570'], ['C12.294.365.700.508'], ['G08.686.784.769'], ['E02.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Single-cell analysis of experience-dependent transcriptomic states in the mouse visual cortex. | Activity-dependent transcriptional responses shape cortical function. However, a comprehensive understanding of the diversity of these responses across the full range of cortical cell types, and how these changes contribute to neuronal plasticity and disease, is lacking. To investigate the breadth of transcriptional ch... | ['Animals', 'Basic Helix-Loop-Helix Transcription Factors', 'Gene Expression Regulation', 'Gene Ontology', 'Light', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Nerve Tissue Proteins', 'Neural Inhibition', 'Neuroglia', 'Neurons', 'Neurovascular Coupling', 'Photic Stimulation', 'Proto-Oncogene Proteins c-fos', 'Signal Transdu... | 29,230,054 | [['B01.050'], ['D12.776.260.103', 'D12.776.930.125'], ['G05.308'], ['H01.158.273.343.249.099', 'H01.770.644.145.350.124', 'L01.224.050.375.480.500.500', 'L01.313.500.750.300.550.500.500', 'L01.453.245.945.079.500'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['B01.050.150.900.649.313.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Target-sensitive immunoliposomes as an efficient drug carrier for antiviral activity. | We have shown previously that target-sensitive immunoliposomes composed of palmitoyl antibody stabilized phosphatidylethanolamine bilayers could be destabilized by binding to the target cells (Ho, R. J. Y., Rouse, B. T., and Huang, L., Biochemistry (1986) 25, 5500-5506). Target-sensitive immunoliposome-encapsulated and... | ['Animals', 'Antibodies, Monoclonal', 'Antibodies, Viral', 'Cell Transformation, Viral', 'Cytarabine', 'L Cells', 'Lipid Bilayers', 'Mice', 'Phosphatidylethanolamines', 'Simplexvirus', 'Viral Envelope Proteins'] | 2,820,987 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['C04.697.098.500.160', 'C23.550.727.098.500.160', 'G06.920.143'], ['D03.383.742.680.245.453', 'D13.570.065.300', 'D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Meta-Analysis of Transcriptional Responses to Mastitis-Causing Escherichia coli. | Bovine mastitis is a widespread disease in dairy cows, and is often caused by bacterial mammary gland infection. Mastitis causes reduced milk production and leads to excessive use of antibiotics. We present meta-analysis of transcriptional profiles of bovine mastitis from 10 studies and 307 microarrays, allowing identi... | ['Animals', 'Cattle', 'Cells, Cultured', 'Escherichia coli', 'Escherichia coli Infections', 'Female', 'Gene Expression Profiling', 'Gene Ontology', 'Mammary Glands, Animal', 'Mastitis, Bovine', 'Staphylococcal Infections', 'Staphylococcus aureus', 'Transcriptome'] | 26,933,871 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['E05.393.332'], ['H01.158.273.343.249.099', 'H01.770.644.145.350.124', 'L01.224.050.375.480.500.500', 'L01.313.500.750.300.550.500.500', 'L01.453.245.945.079.500'], [... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Epidemiology of tuberculosis in the Southeastern Iran. | In order to study the epidemiology of tuberculosis (TB) in Zabol, situated in the Southeast of Iran, this study was performed. Two thousand seven hundred and twenty-nine cases of tuberculosis disease were identified during 1998-2002. The notification rate was 135/100,000 population in 2002, which was higher than this r... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Disease Notification', 'Female', 'Humans', 'Incidence', 'Infant', 'Iran', 'Male', 'Middle Aged', 'Prevalence', 'Retrospective Studies', 'Tuberculosis'] | 16,283,479 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.362', 'N06.850.520.373', 'N06.850.780.200.262'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Health education and the control of intestinal worm infections in China: a new vision. | BACKGROUND: The transmission of soil-transmitted helminths (STHs) is associated with poverty, poor hygiene behaviour, lack of clean water and inadequate waste disposal and sanitation. Periodic administration of benzimidazole drugs is the mainstay for global STH control but it does not prevent re-infection, and is unlik... | ['Adolescent', 'Animals', 'Child', 'Child, Preschool', 'China', 'Health Education', 'Helminthiasis', 'Helminths', 'Humans', 'Hygiene', 'Intestinal Diseases, Parasitic', 'Prevalence', 'Public Health', 'Sanitation', 'Schools', 'Soil', 'Students'] | 25,060,336 | [['M01.060.057'], ['B01.050'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.252.474.164'], ['I02.233.332', 'N02.421.726.407'], ['C01.610.335'], ['B01.050.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.547', 'N06.850.670'], ['C01.610.432', 'C06.405.469.452'], ['E05.318.308.985.525.750', 'N01.224.935.59... | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals... | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Immunoelectron microscopic localization of phosphoproteins associated with the mitotic spindle. | We examined the immunogold staining of microtubules and microtubule organizing centers using an improved silver-enhancement reagent for small (1-1.4 nm) gold-conjugated secondary antibodies. First, the staining properties of different commercial preparations of gold-labeled antibodies were compared for sample penetrati... | ['Animals', 'Cells, Cultured', 'Fluorescent Antibody Technique', 'Humans', 'Immunohistochemistry', 'Interphase', 'Microscopy, Immunoelectron', 'Microtubules', 'Phosphoproteins', 'Rats', 'Spindle Apparatus', 'Tubulin'] | 1,453,002 | [['B01.050'], ['A11.251'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.4... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Mandatory continuing education or periodic reexamination? | A descriptive study of physical therapists located primarily in the southeastern United States was undertaken to determine their opinions concerning mandatory continuing education or reexamination for license renewal. A majority of the 1,187 respondents favored continuing education rather than reexamination. Of those f... | ['Accreditation', 'Attitude', 'Education, Continuing', 'Educational Measurement', 'Humans', 'Licensure', 'Physical Therapy Modalities', 'Surveys and Questionnaires', 'United States'] | 7,243,898 | [['N03.706.110.070', 'N05.700.200.100'], ['F01.100'], ['I02.358.212'], ['I02.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.706.110.510', 'N05.700.200.450'], ['E02.779', 'E02.831.535'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['Z01.107.567.875']] | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Optimizing recovery after laparoscopic colon surgery (ORAL-CS): effect of intravenous ketorolac on length of hospital stay. | BACKGROUND: The objective of this study was to determine if intravenous ketorolac can reduce ileus following laparoscopic colorectal surgery, thus shortening hospital stay.METHODS: This was a prospective, randomized, double-blind, placebo-controlled, clinical trial of patients undergoing laparoscopic colorectal resecti... | ['Aged', 'Analgesia, Patient-Controlled', 'Analgesics, Opioid', 'Anastomosis, Surgical', 'Anti-Inflammatory Agents, Non-Steroidal', 'Colectomy', 'Double-Blind Method', 'Female', 'Humans', 'Ileus', 'Injections, Intravenous', 'Ketorolac', 'Laparoscopy', 'Length of Stay', 'Male', 'Middle Aged', 'Morphine', 'Postoperative ... | 17,440,782 | [['M01.060.116.100'], ['E03.091.120'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E04.035'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['E04.210.219'], ['E05.318.370.300', 'E05.581.500.300', 'N0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Estrogen receptor-beta messenger RNA expression in human breast tumor biopsies: relationship to steroid receptor status and regulation by progestins. | When the level of estrogen receptor (ER)-beta mRNA in tumors, determined by reverse transcription-PCR, was assessed according to either ER status or PR status alone, determined by ligand binding assays, the level of ER-beta mRNA was significantly lower in PR+ tumors compared with PR- tumors (P = 0.036), and no associat... | ['Biopsy', 'Breast Neoplasms', 'Estrogen Receptor beta', 'Female', 'Humans', 'Progestins', 'Protein Isoforms', 'RNA, Messenger', 'Receptors, Estrogen', 'Receptors, Progesterone', 'Tumor Cells, Cultured'] | 9,973,194 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.588.180', 'C17.800.090.500'], ['D12.776.826.750.350.262'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.399.472.858'], ['D12.776.800'], ['D13.444.735.54... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Homeostatic regulation of intrinsic excitability and synaptic transmission in a developing visual circuit. | One of the major challenges faced by the developing visual system is how to stably process visual information, yet at the same time remain flexible enough to accommodate growth and plasticity induced by visual experience. We find that in the Xenopus retinotectal circuit, during a period in development when the retinote... | ['Animals', 'Excitatory Postsynaptic Potentials', 'Homeostasis', 'Nerve Net', 'Superior Colliculi', 'Synaptic Transmission', 'Visual Pathways', 'Xenopus laevis'] | 17,670,973 | [['B01.050'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['G07.410'], ['A08.511'], ['A08.186.211.132.659.800.816'], ['G02.111.820.850', 'G04.835.850', 'G07.265.880', 'G11.561.830'], ['A08.612.220.860'], ['B01.050.150.900.090.180.610.500.562']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Discharge characteristics of axotomized abducens internuclear neurons in the adult cat. | The aim of the present work was to characterize the axotomy-induced changes in the discharge properties of central nervous system neurons recorded in the alert behaving animal. The abducens internuclear neurons of the adult cat were the chosen model. The axons of these neurons course through the contralateral medial lo... | ['Abducens Nerve', 'Action Potentials', 'Age Factors', 'Animals', 'Axotomy', 'Cats', 'Electrophysiology', 'Eye Movements', 'Female', 'Head Movements', 'Interneurons', 'Motor Neurons', 'Ocular Motility Disorders', 'Vestibule, Labyrinth'] | 11,054,701 | [['A08.800.800.120.030'], ['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['E04.525.210.158'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['H01.158.344.528', 'H01.158.782.236'], ['G11.427.410.140', 'G14.350'], ['G11.427.410.478'], ['A08.675.358', 'A11.67... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Digital in vivo 3D atlas of the antennal lobe of Drosophila melanogaster. | As a model for primary olfactory perception, the antennal lobe (AL) of Drosophila melanogaster is among the most thoroughly investigated and well-understood neuronal structures. Most studies investigating the functional properties and neuronal wiring of the AL are conducted in vivo, although so far the AL morphology ha... | ['Animals', 'Animals, Genetically Modified', 'Arthropod Antennae', 'Brain', 'Brain Mapping', 'Drosophila Proteins', 'Drosophila melanogaster', 'Imaging, Three-Dimensional', 'In Vitro Techniques', 'Luminescent Proteins', 'Nerve Net', 'Transcription Factors'] | 25,327,641 | [['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['A13.093'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['D12.776.093.500.462'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['E01.370.350.400', 'L01.224.308.410'], ['E05.481'], ['D12.776.532'], ['A08.511'], ['D1... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Damage of chromosoms under irradiation of human blood lymphocytes and development of bystander effect. | OBJECTIVE: the research the distribution of radiation induced damages among chromosomes and their bands in irra diated in vitro human blood lymphocytes and in unirradiated bystander cells.Material and methods of research: cultivation of human peripheral blood lymphocytes by semi micromethod D.A. Hungerford, modeling of... | ['Bystander Effect', 'Chromosome Aberrations', 'Cytogenetic Analysis', 'Dose-Response Relationship, Radiation', 'Humans', 'Lymphocytes', 'Telomere'] | 28,027,549 | [['G04.085.155'], ['C23.550.210', 'G05.365.590.175'], ['E01.370.225.500.385', 'E05.200.500.385', 'E05.242.385', 'E05.393.285'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567', 'A15.145.229.63... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Modification of the adenosine 5'-triphosphate-sensitive K+ channel by trypsin in guinea-pig ventricular myocytes. | 1. The adenosine 5'-triphosphate (ATP)-sensitive K+ channel current was recorded in guinea-pig ventricular myocytes using the patch clamp technique with inside-out patch configuration. Modification of the channel activity by intracellular application of an endoprotease trypsin was studied, and was related to a possible... | ['Adenosine Triphosphate', 'Animals', 'Calcium', 'Carboxypeptidases', 'Carboxypeptidases A', 'Drug Resistance', 'Electric Conductivity', 'Ethers, Cyclic', 'Guinea Pigs', 'Heart Ventricles', 'In Vitro Techniques', 'Kinetics', 'Myocardium', 'Okadaic Acid', 'Phosphoprotein Phosphatases', 'Potassium Channels', 'Trypsin'] | 8,410,713 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D08.811.277.656.350.245'], ['D08.811.277.656.350.245.250', 'D08.811.277.656.350.555.350', 'D08.811.277.656.675.555.350'], ['G07.690.773.984'], ['G01.358.500.249.277'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Peroxisome proliferation-activated receptor-gamma ligands ameliorate experimental autoimmune myocarditis. | BACKGROUND: Peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligands have been shown to ameliorate a variety of inflammatory conditions. The present study tested the hypothesis that PPAR-gamma ligands reduce experimental autoimmune myocarditis (EAM) associated with inhibition of the expansion and activatio... | ['Animals', 'Autoimmune Diseases', 'Hypoglycemic Agents', 'Interleukin-1', 'Models, Animal', 'Myocarditis', 'Pioglitazone', 'Prostaglandin D2', 'Rats', 'Rats, Inbred Lew', 'Receptors, Cytoplasmic and Nuclear', 'Thiazolidinediones', 'Transcription Factors'] | 14,499,870 | [['B01.050'], ['C20.111'], ['D27.505.696.422'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D23.529.374.465.131', 'D23.529.374.500.400'], ['E05.598'], ['C14.280.238.625'], ['D02.886.675.933.250', 'D03.383.129.708.933.250'], ['D10.251.355.255.550.200.200'... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neurothelin: amino acid sequence, cell surface dynamics and actin colocalization. | Neurothelin is a cell surface protein of chicken endothelial cells at the blood-brain barrier and also of pigment epithelial cells forming the blood-eye barrier. Peptide sequencing of affinity-purified neurothelin revealed that it is likely to be identical with the protein called HT7. It belongs to the immunoglobulin s... | ['Actin Cytoskeleton', 'Actins', 'Amino Acid Sequence', 'Animals', 'Antigens, CD', 'Antigens, Neoplasm', 'Antigens, Surface', 'Avian Proteins', 'Basigin', 'Blood Proteins', 'Blood-Brain Barrier', 'Blood-Retinal Barrier', 'Cell Communication', 'Chick Embryo', 'Chickens', 'Cytochalasin D', 'Cytoskeleton', 'Endothelium, V... | 8,575,462 | [['A11.284.430.214.190.750.050'], ['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.285'], ['D23.050.301'], ['D12.776.095'], ['D12.776.395.550.045', 'D12.776.543.550.187', 'D23.050.285.040... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Time-dependent postmortem redistribution of butyrfentanyl and its metabolites in blood and alternative matrices in a case of butyrfentanyl intoxication. | A fatal case of butyrfentanyl poisoning was investigated at the Zurich Institute of Forensic Medicine. At admission at the institute approx. 9h after death (first time point, t1), femoral and heart blood (right ventricle) was collected, as well as samples from the lung, liver, kidney, spleen, muscle and adipose tissue ... | ['Autopsy', 'Chromatography, Liquid', 'Fentanyl', 'Humans', 'Postmortem Changes', 'Time Factors', 'Tissue Distribution'] | 27,289,433 | [['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E05.196.181.400'], ['D03.383.621.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.260.224.617'], ['G01.910.857'], ['G03.787.917', 'G07.690.725.949']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Structural alterations in the latissimus dorsi muscles in three patients more than 2 years after a cardiomyoplasty procedure. | AIMS: The long-term effects of the use of the latissimus dorsi muscle for dynamic cardiomyoplasty were studied. Skeletal muscle fast fatiguable type II fibres are transformed to highly fatigue-resistant type I fibres in animal models, and is assumed to occur in men. However, it is not known whether this same transforma... | ['Aged', 'Cardiac Output, Low', 'Cardiomyoplasty', 'Electric Stimulation', 'Fatal Outcome', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Muscle Fibers, Fast-Twitch', 'Muscle Fibers, Slow-Twitch', 'Muscle, Skeletal'] | 9,519,326 | [['M01.060.116.100'], ['C14.280.148', 'C23.888.192'], ['E04.100.376.125', 'E04.928.220.220'], ['E05.723.402'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Recurrent aphthous stomatitis: investigation of possible etiologic factors. | OBJECTIVE: To investigate the association of serum vitamin B(12), folic acid, iron, calcium, magnesium, and phosphorus levels as well as family history and cigarette smoking with recurrent aphthous stomatitis (RAS).METHODS: Thirty-four patients with RAS and 32 control subjects were included in this controlled prospecti... | ['Adolescent', 'Adult', 'Aged', 'Calcium', 'Causality', 'Chi-Square Distribution', 'Child', 'Female', 'Folic Acid', 'Humans', 'Iron', 'Logistic Models', 'Magnesium', 'Male', 'Middle Aged', 'Phosphorus', 'Prospective Studies', 'Recurrence', 'Risk Factors', 'Smoking', 'Stomatitis, Aphthous', 'Vitamin B 12', 'Vitamin B 12... | 16,798,397 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['N05.715.350.200', 'N06.850.490.625'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.060.406'], ['D03.633.100.733.631.400'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Evaluation of acceptance rate and outcome of renal replacement therapy in patients with diabetic nephropathy--multicenter study]. | Development of dialysis methods and progress in kidney and pancreas transplantation allowed to treat an increasing number of patients suffering from diabetic nephropathy (D.N.). This report evaluates availability and results of treatment in these patients. 31.12.93 in Gdansk and Bydgoszcz area there were treated 519 pa... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Diabetes Mellitus, Type 1', 'Diabetes Mellitus, Type 2', 'Diabetic Nephropathies', 'Female', 'Humans', 'Infant', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Renal Dialysis', 'Retrospective Studies', 'Treatment Outcome'] | 8,650,029 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C18.452.394.750.149', 'C19.246.300'], ['C12.777.419.192', 'C13.351.968.419.192', 'C19.246.099.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fractures of the greater tuberosity presenting as rotator cuff abnormality: magnetic resonance demonstration. | BACKGROUND: To show that magnetic resonance imaging (MRI) can be useful to diagnose radiographically invisible greater tuberosity fractures in patients with clinical presentations suspicious for rotator cuff injury.METHODS: Six patients with subtle greater tuberosity fractures who were sent for MRI because of possible ... | ['Accidental Falls', 'Adult', 'Diagnostic Errors', 'Female', 'Hockey', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Rotation', 'Rotator Cuff Injuries', 'Sensitivity and Specificity', 'Shoulder Fractures', 'Skating'] | 9,555,840 | [['N06.850.135.122'], ['M01.060.116'], ['E01.354', 'N02.421.450.280'], ['I03.450.642.845.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['G01.482.703'], ['C26.761.340', 'C26.803.063', 'C26.874.400'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.32... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Cost-effectiveness model of empiric doripenem compared with imipenem-cilastatin in ventilator-associated pneumonia. | BACKGROUND: Ventilator-associated pneumonia (VAP) is a common complication of critical illness among surgical and trauma patients. Inappropriate empiric treatment of VAP increases the mortality rate. The rates of Pseudomonas aeruginosa (PA) VAP susceptibility to doripenem (DOR) are higher than those to imipenem-cilasta... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Carbapenems', 'Cilastatin', 'Cilastatin, Imipenem Drug Combination', 'Cost-Benefit Analysis', 'Doripenem', 'Drug Combinations', 'Humans', 'Imipenem', 'Length of Stay', 'Middle Aged', 'Pneumonia, Ventilator-Associated', 'Pseudomonas Infection... | 20,666,580 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['D02.065.589.099.124', 'D03.633.100.300.124'], ['D02.455.426.392.368.533.200', 'D10.251.355.325.200'], ['D02.065.589.099.124.300.500.500', 'D02.455.426.392.368.533.200.500', 'D03.633.100.300.124.300.500.500', 'D10... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Osteoactivin inhibition of osteoclastogenesis is mediated through CD44-ERK signaling. | Osteoactivin is a heavily glycosylated protein shown to have a role in bone remodeling. Previous studies from our lab have shown that mutation in Osteoactivin enhances osteoclast differentiation but inhibits their function. To date, a classical receptor and a signaling pathway for Osteoactivin-mediated osteoclast inhib... | ['Animals', 'Cell Differentiation', 'Cells, Cultured', 'Eye Proteins', 'Hyaluronan Receptors', 'MAP Kinase Signaling System', 'Male', 'Membrane Glycoproteins', 'Mice, Inbred C57BL', 'Osteoclasts', 'RANK Ligand', 'Recombinant Proteins', 'Signal Transduction'] | 27,585,719 | [['B01.050'], ['G04.152'], ['A11.251'], ['D12.776.306'], ['D09.698.735.200.625', 'D12.776.395.550.200.625.144', 'D12.776.395.650.750.281', 'D12.776.543.550.200.625.144', 'D12.776.543.750.705.877.144', 'D23.050.301.350.625.144'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['D12.776.395.550', 'D12.776.543.550'], ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of Bacterial Microbiota in Tilapia Fillets Under Different Storage Temperatures. | This paper investigates the bacterial microbiota in tilapia fillets under cold (4 °C), iced (0 °C), and superchilled (-3 °C) storage conditions. At 4 °C, at least seven species/strains of Pseudomonas were detected in the fillets, five of which were dominant either at a certain stage or throughout the entire storage per... | ['Animals', 'Bacteria', 'Bacterial Load', 'Cold Temperature', 'DNA, Bacterial', 'DNA, Ribosomal', 'Food Storage', 'Microbiota', 'Pseudomonas', 'RNA, Ribosomal, 16S', 'Serratia', 'Temperature', 'Tilapia', 'Time Factors'] | 31,066,925 | [['B01.050'], ['B03'], ['E01.370.225.875.150.115', 'E01.370.225.875.220.115', 'E05.200.875.150.115', 'E05.200.875.220.115', 'G06.099.100'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['D13.444.308.212'], ['D13.444.308.475'], [... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Clinical Benefit of Preoperative Exercise and Nutritional Therapy for Patients Undergoing Hepato-Pancreato-Biliary Surgeries for Malignancy. | BACKGROUND: The impact of prehabilitation on physical fitness and postoperative course after hepato-pancreato-biliary (HPB) surgeries for malignancy is unknown. The current study aimed to investigate the effect of preoperative exercise and nutritional therapies on nutritional status, physical fitness, and postoperative... | ['Aged', 'Biliary Tract Neoplasms', 'Biliary Tract Surgical Procedures', 'Exercise Therapy', 'Female', 'Follow-Up Studies', 'Hepatectomy', 'Humans', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Nutrition Therapy', 'Pancreatic Neoplasms', 'Pancreaticoduodenectomy', 'Postoperative Complications', 'Preoperative Care', 'Prog... | 30,367,303 | [['M01.060.116.100'], ['C04.588.274.120', 'C06.130.320', 'C06.301.120'], ['E04.210.120'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.210.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pet fish radiography: technique and case history reports. | Radiography can be used to aid in the diagnosis and treatment of pet fish diseases. Handling, restraint and radiographic technique for the radiographic examination of pet fish is described. Quality diagnostic images can be obtained with standard radiographic equipment and radiographic techniques. Fishes with undifferen... | ['Air Sacs', 'Anesthesia, General', 'Anesthetics, General', 'Animals', 'Animals, Domestic', 'Bone Diseases', 'Carps', 'Female', 'Fish Diseases', 'Fishes', 'Goldfish', 'Hernia', 'Magnetic Resonance Imaging', 'Mesylates', 'Radiographic Image Enhancement', 'Respiratory Tract Diseases', 'Restraint, Physical', 'Safety', 'Sa... | 9,238,766 | [['A13.048'], ['E03.155.197'], ['D27.505.696.277.100.035', 'D27.505.954.427.210.100.035'], ['B01.050'], ['B01.050.050.116'], ['C05.116'], ['B01.050.150.900.493.200.244.248'], ['C22.362'], ['B01.050.150.900.493'], ['B01.050.150.900.493.200.244.248.480'], ['C23.300.707'], ['E01.370.350.825.500'], ['D02.455.326.146.100.05... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Effect of different vitamin D supplementations in poultry feed on vitamin D content of eggs and chicken meat. | According to a new European Union regulation, vitamin D(3) can be partially or totally substituted with 25-hydroxyvitamin D(3) (25-OH-D(3)) in hens' feed. The purpose of this study was to clarify how this regulation has affected the vitamin D content of commercial eggs and chicken meat. Another aim was to investigate h... | ['Animal Feed', 'Animals', 'Chickens', 'Cholecalciferol', 'Dietary Supplements', 'Eggs', 'Female', 'Male', 'Meat'] | 21,696,169 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D04.210.500.247.222.159', 'D04.210.500.247.808.146', 'D04.210.500.812.768.196', 'D10.570.938.146'], ['G07.203.300.456', 'J02.500.456'], ['G07.203.300.470', 'J02.500.470'], ['G07.203.300.600', 'J02... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Engineering Human Stem Cell Lines with Inducible Gene Knockout using CRISPR/Cas9. | Precise temporal control of gene expression or deletion is critical for elucidating gene function in biological systems. However, the establishment of human pluripotent stem cell (hPSC) lines with inducible gene knockout (iKO) remains challenging. We explored building iKO hPSC lines by combining CRISPR/Cas9-mediated ge... | ['Base Sequence', 'CRISPR-Cas Systems', 'Cell Differentiation', 'Exons', 'Gene Expression Regulation', 'Gene Knock-In Techniques', 'Gene Knockout Techniques', 'Gene Targeting', 'Genetic Engineering', 'Homozygote', 'Humans', 'Molecular Sequence Data', 'Mutagenesis, Insertional', 'Otx Transcription Factors', 'Phospholipi... | 26,145,478 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.308.203.374.394'], ['G04.152'], ['G05.360.340.024.340.137.232'], ['G05.308'], ['E05.393.335.249'], ['E05.393.335.750'], ['E05.393.335'], ['E05.393.420'], ['G05.380.554'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['E05.393.420... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Randomized trial of 8-week versus 12-week VNCOP-B plus G-CSF regimens as front-line treatment in elderly aggressive non-Hodgkin's lymphoma patients. | BACKGROUND: Among the third-generation chemotherapy regimens specifically adapted in the last decade for elderly aggressive non-Hodgkin's lymphoma (NHL) patients, we designed an 8-week cyclophosphamide, mitoxantrone, vincristine, etoposide, bleomycin and prednisone (VNCOP-B) plus granulocyte colony-stimulating factor (... | ['Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Bleomycin', 'Cyclophosphamide', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Etoposide', 'Female', 'Granulocyte Colony-Stimulating Factor', 'Humans', 'Italy', 'Logistic Models', 'Lymphoma, Non-Hodgkin', 'Male', 'Mid... | 12,196,361 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D09.400.420.110', 'D12.644.233.110'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['D02.455.426.559.847.638.960.675.250', 'D04.615.638.960.675.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
CRY-DASH gene expression is under the control of the circadian clock machinery in tomato. | Recently a new member of the blue-light photoreceptor family, CRY-DASH, was reported in Arabidopsis, though its distinctive biological functions are still unclear. We characterized the CRY-DASH gene of tomato and evidenced that its mRNA is expressed in both seeds and adult organs showing diurnal and circadian fluctuati... | ['Amino Acid Sequence', 'Circadian Rhythm', 'Flavoproteins', 'Gene Expression Regulation, Plant', 'In Situ Hybridization', 'Lycopersicon esculentum', 'Molecular Sequence Data', 'Sequence Homology, Nucleic Acid'] | 16,876,787 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G07.180.562.190'], ['D12.776.331'], ['G05.308.375'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['B01.650.940.800.575.912.250.908.500.322'], ['L01.453.245.667'], ['G02.111.810.550... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
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