Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Biliary interleukin-6 and tumor necrosis factor-alpha in patients undergoing endoscopic retrograde cholangiopancreatography. | Cytokines are low-molecular-weight protein mediators that possess a wide spectrum of inflammatory, metabolic, and immunomodulatory properties. Cytokines have been shown to be produced by monocytes/macrophages, lymphocytes, fibroblasts, endothelial cells, and more recently, hepatocytes and biliary epithelium. The aim of... | ['Bacterial Infections', 'Bile', 'Biliary Tract Diseases', 'Cholangiopancreatography, Endoscopic Retrograde', 'Cholangitis', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Interleukin-6', 'Sensitivity and Specificity', 'Tumor Necrosis Factor-alpha'] | 9,201,097 | [['C01.150.252'], ['A12.200.087'], ['C06.130'], ['E01.370.350.700.715.200.200', 'E01.370.372.200.200', 'E01.370.372.250.200', 'E01.370.388.250.250.160', 'E04.210.240.160', 'E04.502.250.250.160'], ['C06.130.120.200'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.4... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Neural basis of auditory-induced shifts in visual time-order perception. | Attended objects are perceived to occur before unattended objects even when the two objects are presented simultaneously. This finding has led to the widespread view that attention modulates the speed of neural transmission in the various perceptual pathways. We recorded event-related potentials during a time-order jud... | ['Acoustic Stimulation', 'Adult', 'Attention', 'Auditory Perception', 'Brain Mapping', 'Cues', 'Electroencephalography', 'Evoked Potentials', 'Female', 'Functional Laterality', 'Humans', 'Male', 'Photic Stimulation', 'Reaction Time', 'Time Factors', 'Time Perception', 'Visual Cortex', 'Visual Perception'] | 16,056,224 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.116'], ['F02.830.104.214'], ['F02.463.593.071', 'G07.888.125'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.425.234'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['F02.830.297.425', 'G... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
T-cell compartment in synovial fluid of pediatric patients with JIA correlates with disease phenotype. | INTRODUCTION: Juvenile idiopathic arthritis (JIA) is an autoimmune disease where T cells are key players. It can be classified into two main clinical diseases: polyarticular and pauciarticular, based on the number of joints involved. Oligoarthritis, which is considered a pauciarticular subtype since it involves up to f... | ['Adolescent', 'Antirheumatic Agents', 'Arthritis, Juvenile', 'Child', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Genes, T-Cell Receptor', 'Humans', 'Male', 'Predictive Value of Tests', 'Synovial Fluid', 'T-Lymphocytes'] | 21,901,393 | [['M01.060.057'], ['D27.505.954.329'], ['C05.550.114.122', 'C05.799.056', 'C17.300.775.049', 'C20.111.198'], ['M01.060.406'], ['C23.550.291.656'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G05.360.340.024.340.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Flavopiridol, a protein kinase inhibitor, down-regulates hypoxic induction of vascular endothelial growth factor expression in human monocytes. | We have investigated the effects of flavopiridol, a novel protein kinase inhibitor that is selective for cyclin-dependent kinases, on hypoxia-induced vascular endothelial growth factor (VEGF) expression in human monocytes. We found that hypoxia induces a time-dependent increase of VEGF mRNA expression and protein level... | ['Blotting, Northern', 'Dose-Response Relationship, Drug', 'Down-Regulation', 'Endothelial Growth Factors', 'Enzyme Inhibitors', 'Flavonoids', 'Humans', 'Hypoxia', 'Luciferases', 'Lymphokines', 'Monocytes', 'Piperidines', 'Protein Kinase Inhibitors', 'RNA, Messenger', 'Time Factors', 'Transcriptional Activation', 'Tran... | 10,554,012 | [['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['G07.690.773.875', 'G07.690.936.500'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D12.644.276.390', 'D12.776.467.390', 'D23.529.390'], ['D27.505.519.389'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['B01.050.150.900.649.313.988.400.112.400... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The more and smaller cells mutants of Arabidopsis thaliana identify novel roles for SQUAMOSA PROMOTER BINDING PROTEIN-LIKE genes in the control of heteroblasty. | Regulation of cell number and cell size is essential for controlling the shape and size of leaves. Here, we report a novel class of Arabidopsis thaliana mutants, more and smaller cells 1 (msc1)-msc3, which have increased cell number and decreased cell size in leaves. msc1 has a miR156-resistant mutation in the SQUAMOSA... | ['Arabidopsis', 'Arabidopsis Proteins', 'Base Sequence', 'Gene Expression Regulation, Plant', 'Karyopherins', 'MicroRNAs', 'Mutation', 'Phenotype', 'Plant Leaves', 'Transcription Factors'] | 19,211,679 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.308.375'], ['D12.776.157.530.750.500', 'D12.776.543.585.750.500', 'D12.776.660.502'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['G05.365.590'], ['G05.695'], ['A18... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Diagnostic value of two immunoassays for detecting heparin/PF4 complex antibodies in heparin-induced thrombocytopenia]. | Objectives: To assess the diagnostic values of latex immunoturbidimetric assay (LIA) and particle immunofiltration assay (PIFA) for heparin-induced thrombocytopenia (HIT) . Methods: Samples from 94 patients with suspected HIT from May 2016 to July 2018 in our hospital were prospectively analyzed by the two immunoassays... | ['Antibodies', 'Anticoagulants', 'Enzyme-Linked Immunosorbent Assay', 'Heparin', 'Humans', 'Immunoassay', 'Platelet Factor 4', 'Thrombocytopenia'] | 31,207,707 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D27.505.954.502.119'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Galactosamine-induced alpha 1-antitrypsin deficiency in rats. Alterations in plasma glycoproteins and alpha 1-antitrypsin carbohydrate composition. | Administration of D-galactosamine (GalNH2) is known to produce alterations in plasma glycoprotein levels, including alpha 1-antitrypsin. The authors have studied the effects of GalNH2 on circulating protein bound carbohydrates and on the plasma concentrations of two alpha 1-antiproteases, transferrin, IgG, and albumin ... | ['Animals', 'Blood Proteins', 'Body Weight', 'Carbohydrates', 'Galactosamine', 'Glycoproteins', 'Liver', 'Male', 'Protein Binding', 'Rats', 'Rats, Inbred Strains', 'Trypsin', 'alpha 1-Antitrypsin', 'alpha 1-Antitrypsin Deficiency'] | 3,493,700 | [['B01.050'], ['D12.776.124'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D09'], ['D09.067.342.356'], ['D09.400.430', 'D12.776.395'], ['A03.620'], ['G02.111.679', 'G03.808'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.76... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Ectopic hamartomatous thymoma. Case report with special reference to differential diagnosis]. | We report the case of an ectopic hamartomatous thymoma in a 56-year-old male patient. The lesion arose subcutaneously in the supraclavicular region. Histologically, the well-circumscribed but unencapsulated tumour was composed of uniform fusiform tumour cells. In addition, mature fatty tissue, scattered T-lymphocytes, ... | ['Biomarkers, Tumor', 'Choristoma', 'Clavicle', 'Diagnosis, Differential', 'Humans', 'Immunoenzyme Techniques', 'Male', 'Microscopy, Electron', 'Middle Aged', 'Soft Tissue Neoplasms', 'Thymoma', 'Thymus Gland'] | 7,479,610 | [['D23.101.140'], ['C23.300.250'], ['A02.835.232.087.227'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['E01.370.350.515.402', 'E05.595.402'], ['M01.060.116.630'], ['C04.588.839'], ['C04.557.435.850', 'C04.588.894.949.500', 'C15.604.861.800']... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cognitive task avoidance correlates with fatigue-induced performance decrement but not with subjective fatigue. | Mentally demanding tasks feel effortful and are usually avoided. Furthermore, prolonged cognitive engagement leads to mental fatigue, consisting of subjective feeling of exhaustion and decline in performance. Despite the intuitive characterization of fatigue as an increase in subjective effort perception, the effect of... | ['Adult', 'Avoidance Learning', 'Choice Behavior', 'Cognition', 'Female', 'Humans', 'Male', 'Memory, Short-Term', 'Mental Fatigue', 'Neuropsychological Tests', 'Young Adult'] | 29,936,122 | [['M01.060.116'], ['F02.463.425.097', 'F02.463.785.373.173'], ['F02.463.785.373.346'], ['F02.463.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.407'], ['C23.888.369.500', 'F01.145.126.937'], ['F04.711.513'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Proteomic analysis of neonatal mouse brain: evidence for hypoxia- and ischemia-induced dephosphorylation of collapsin response mediator proteins. | Perinatal hypoxia and ischemia (HI) are a significant cause of mortality and morbidity. To understand the molecular mechanisms for HI-induced brain damage, here we used a proteomic approach to analyze the alteration and modification of proteins in neonatal mouse brain 24 h after HI treatment. Significant changes of col... | ['Alkaline Phosphatase', 'Amidohydrolases', 'Animals', 'Animals, Newborn', 'Brain', 'Cerebral Cortex', 'Cyclin-Dependent Kinase 5', 'Electrophoresis, Gel, Two-Dimensional', 'Hippocampus', 'Hydrolases', 'Hypoxia-Ischemia, Brain', 'Intercellular Signaling Peptides and Proteins', 'Mice', 'Mice, Inbred C57BL', 'Microtubule... | 18,471,005 | [['D08.811.277.352.650.035'], ['D08.811.277.087'], ['B01.050'], ['B01.050.050.282'], ['A08.186.211'], ['A08.186.211.200.885.287.500'], ['D08.811.913.696.620.682.700.646.500.500.500', 'D12.644.360.250.067.875', 'D12.776.167.200.067.875', 'D12.776.476.250.067.875'], ['E05.196.401.250', 'E05.301.300.230'], ['A08.186.211.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of a self-etching primer on enamel shear bond strengths and SEM morphology. | PURPOSE: To study a dental adhesive system containing a self-etching primer, by evaluating the enamel shear bond strengths and comparing the SEM interfacial morphology.MATERIALS AND METHODS: 100 flat enamel bonding sites were prepared to 600-grit on proximal surfaces of caries-free human molars. The bonding surfaces we... | ['Acid Etching, Dental', 'Analysis of Variance', 'Dental Bonding', 'Dental Enamel', 'Dentin-Bonding Agents', 'Humans', 'Materials Testing', 'Methacrylates', 'Microscopy, Electron, Scanning', 'Organophosphorus Compounds'] | 9,580,237 | [['E06.931.475.111'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E06.095'], ['A14.549.167.900.255'], ['D25.339.291.300', 'J01.637.051.339.291.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.570'], ['D02.241.081.069.600'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['D02.705'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Immunohistochemical detection of vascular endothelial growth factor (VEGF) in the vasculature of oligodendrogliomas. | Vascular endothelial growth factor (VEGF) appears to be implicated in tumour angiogenesis. In the present study immunohistochemical expression of VEGF was evaluated in 34 oligodendrogliomas (13 grade II, 21 grade III [WHO]). VEGF immunoreactivity was found in 31 of 34 cases. Expression of VEGF was observed in endotheli... | ['Brain Neoplasms', 'Endothelial Growth Factors', 'Endothelium, Vascular', 'Glycoproteins', 'Humans', 'Immunohistochemistry', 'Oligodendroglioma', 'Staining and Labeling', 'Vascular Endothelial Growth Factor A'] | 9,549,726 | [['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['D12.644.276.390', 'D12.776.467.390', 'D23.529.390'], ['A07.015.700.500', 'A10.272.491.355'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitative X-ray microanalysis of bulk hydrated specimens: a method using gelatine standards. | A method of preparing and using gelatine blocks as standards for quantitative X-ray microanalysis of bulk hydrated tissue is described. Each series of standards had several constant and one variable element. The average deviations in the X-ray counts of the constant elements from the series means were used to correct t... | ['Electron Probe Microanalysis', 'Freezing', 'Gelatin', 'Phosphorus', 'Potassium', 'Sodium'] | 3,668,736 | [['E01.370.350.515.402.250', 'E05.196.867.800.360', 'E05.595.402.250', 'E05.799.830.360'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['D12.776.860.476'], ['D01.268.666'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['D01.268.549.750', 'D01.268.557.650', 'D01.552.528.850', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Carryover of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) from soil to plants. | Within the scope of a joint project to study soil-to-plant carryover of polyfluorinated compounds (PFCs), five cultivated plants (spring wheat, oats, potatoes, maize, and perennial ryegrass) were sown or planted in Mitscherlich pots. Six variants per species were used, each with a different concentration level of PFOA ... | ['Alkanesulfonic Acids', 'Animal Feed', 'Caprylates', 'Chromatography, High Pressure Liquid', 'Fluorocarbons', 'Food Analysis', 'Plant Development', 'Plants', 'Soil', 'Tandem Mass Spectrometry'] | 19,112,561 | [['D02.455.326.146.100', 'D02.886.645.600.055'], ['G07.203.300.300.100', 'J02.500.300.100'], ['D02.241.081.222', 'D10.251.122'], ['E05.196.181.400.300'], ['D02.455.526.510.435'], ['E05.362', 'J01.576.423.850.100'], ['G07.345.625', 'G15.589'], ['B01.650'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Intraocular pressure determination in clinically normal red-footed tortoise (Geochelone carbonaria). | Intraocular pressure (IOP) reflects a balance between aqueous humor production and outflow and is often an essential ophthalmic diagnostic procedure in animals. The objective of this study was to estimate IOP in clinically normal red-footed tortoises (Geochelone carbonaria) of various sizes by using applanation tonomet... | ['Analysis of Variance', 'Animals', 'Body Constitution', 'Female', 'Intraocular Pressure', 'Male', 'Reproducibility of Results', 'Sex Factors', 'Tonometry, Ocular', 'Turtles'] | 12,216,794 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['E01.370.600.115', 'G07.100'], ['G14.440'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['N05.715.350.675', 'N06.850.490.875'], ['E01.370.380.750'], ['B01.050.150.900.833.848']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Stereoselective glycosylations using oxathiane spiroketal glycosyl donors. | Novel oxathiane spiroketal donors have been synthesised and activated via an umpolung S-arylation strategy using 1,3,5-trimethoxybenzene and 1,3-dimethoxybenzene. The comparative reactivity of the resulting 2,4,6-trimethoxyphenyl (TMP)- and 2,4-dimethoxyphenyl (DMP)-oxathiane spiroketal sulfonium ions is discussed, and... | ['Anisoles', 'Crystallography, X-Ray', 'Furans', 'Glycosides', 'Glycosylation', 'Heterocyclic Compounds, 1-Ring', 'Magnetic Resonance Spectroscopy', 'Molecular Structure', 'Phloroglucinol', 'Spiro Compounds', 'Stereoisomerism', 'Sulfonium Compounds', 'Thioglycosides'] | 22,200,482 | [['D02.355.601.200', 'D02.355.726.158', 'D02.455.426.559.389.657.654.158'], ['E05.196.309.742.225'], ['D03.383.312'], ['D09.408'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['D03.383'], ['E05.196.867.519'], ['G02.111.570', 'G02.466'], ['D02.455.426.559.389.657.684'], ['D02.455.426.779', 'D04.711'], ['G02.607.4... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
68Ga-DOTA-Tyr3-octreotide PET for assessing response to somatostatin-receptor-mediated radionuclide therapy. | UNLABELLED: (68)Ga-labeled 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid-d-Phe(1)-Tyr(3)-octreotide (DOTA-TOC) PET has proven its usefulness in the diagnosis of patients with neuroendocrine tumors. Radionuclide therapy ((90)Y-DOTA-TOC or (177)Lu-DOTA-octreotate) is a choice of treatment that also requir... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neuroendocrine Tumors', 'Octreotide', 'Organometallic Compounds', 'Positron-Emission Tomography', 'Prognosis', 'Radiopharmaceuticals', 'Receptors, Somatostatin', 'Reproducibility of Results', 'Sensitivity an... | 19,690,033 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C04.557.465.625.650', 'C04.557.580.625.650'], ['D04.345.566.650', 'D12.644.641.650'], ['D02.691'], ['E01.370.350.350.800.700', 'E01.370.350.600.350.800.399', '... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
PCR detection and characterization of type-2 porcine circovirus. | A polymerase chain reaction (PCR) assay was developed for detecting porcine circovirus (PCV). The assay readily detected type-2 PCV (PCV-2) and type-1 PCV (PCV-1). The PCR primers were designed based on DNA sequences conserved in all reported PCV genomes. Type 1 PCV and type 2 PCV both produced 438 bp amplification pro... | ['Animals', 'Base Sequence', 'Circoviridae Infections', 'Circovirus', 'DNA Primers', 'DNA, Viral', 'Molecular Epidemiology', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Sensitivity and Specificity', 'Swine', 'Swine Diseases'] | 10,680,656 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C01.925.256.200'], ['B04.280.120.150'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.568'], ['E05.318.416', 'E05.393.522', 'H01.158.201.636.475.500', 'H01.158.273.343.595.475.500', 'H01.181.122.650.475.550', 'H02.403... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Induction of transplantation tolerance in humans using fetal cell transplants. | When engrafted with donor stem cells and lymphoid cells, patients develop transplantation tolerance to donor antigens. We analyzed the mechanism of tolerance induction in immunoincompetent recipients whose immunity has been reconstituted by transplantation of mismatched stem cells. Seven infants or human fetuses receiv... | ['Fetal Tissue Transplantation', 'Humans', 'Infant', 'Isoantigens', 'Severe Combined Immunodeficiency', 'T-Lymphocytes', 'T-Lymphocytes, Cytotoxic', 'T-Lymphocytes, Helper-Inducer', 'Transplantation Tolerance', 'Transplantation, Homologous'] | 15,808,548 | [['E02.095.147.725.300', 'E04.936.580.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D23.050.705'], ['C16.320.798.750', 'C16.614.815', 'C18.452.284.800', 'C20.673.795.750'], ['A11.118.637.555.567.569', 'A15.145.229.637.555.567.569', 'A15.382.490.555.567.569'], ['A11.118.637.555.283.875', 'A1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Restrictive antibiotherapy after renal transplantation. | Forty-two patients were followed up after 44 renal transplantations in an effort to evaluate possible benefits from the following protocol: systematic microbiologic and clinical surveillance, early and aggressive research for the cause of suspected infections, refusal to use prophylactic antibiotherapy, and selection o... | ['Adult', 'Anti-Bacterial Agents', 'Anti-Infective Agents', 'Bacterial Infections', 'Female', 'Follow-Up Studies', 'Graft Survival', 'Humans', 'Immunosuppression', 'Infections', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Postoperative Complications', 'Skin Diseases, Infectious', 'Transplantation, Homologous', 'U... | 376,078 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Practical approach to solid-phase synthesis of C-terminal peptide amides under mild conditions based on a photolysable anchoring linkage. | Several 3-nitro-4-(N-protected aminomethyl)benzoic acids; with protection provided by tert.-butyloxycarbonyl (Boc), 9-fluorenylmethyloxycarbonyl (Fmoc), trifluoroacetyl (Tfa), dithiasuccinoyl (Dts), or phthaloyl (Phth), have been prepared by reproducible routes. Synthesis of Dts-handle 6 illustrates some particularly n... | ['Amides', 'Molecular Structure', 'Peptides', 'Photolysis'] | 2,401,599 | [['D02.065'], ['G02.111.570', 'G02.466'], ['D12.644'], ['G02.740.685']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
RASopathic comedone-like or cystic lesions induced by vemurafenib: a model of skin lesions similar but not identical to those induced by dioxins MADISH. | BACKGROUND: Patients treated with vemurafenib for metastatic melanoma often develop skin lesions similar to those observed after exposure to dioxin-like compounds. We previously called these lesions MADISH (metabolizing acquired dioxin-induced skin hamartoma) when analysing a case of acute dioxin poisoning.OBJECTIVE: W... | ['Antineoplastic Agents', 'Chloracne', 'Cytochrome P-450 CYP1A1', 'Dioxins', 'Drug Eruptions', 'Enzyme Activation', 'Epidermal Cyst', 'Erlotinib Hydrochloride', 'Female', 'Gefitinib', 'Hep G2 Cells', 'Humans', 'Male', 'Melanoma', 'Protein Kinase Inhibitors', 'Skin Neoplasms', 'Vemurafenib'] | 29,575,357 | [['D27.505.954.248'], ['C17.800.030.575'], ['D08.244.453.005.332', 'D08.244.453.100.500', 'D08.811.682.690.708.170.010.277', 'D08.811.682.690.708.170.020.500', 'D12.776.422.220.453.010.332', 'D12.776.422.220.453.100.500'], ['D02.309.500', 'D03.383.231'], ['C17.800.174.600', 'C20.543.206.380', 'C25.100.468.380'], ['G02.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reducing alcohol consumption during pre-drinking sessions: testing an integrated behaviour-change model. | OBJECTIVE: Pre-drinking, the practice of consuming alcohol prior to attending a subsequent event, increases the risk of alcohol-related harm, and is common in undergraduate student populations. The current study tested an integrated behaviour change model to identify the motivational, social-cognitive, and implicit pre... | ['Adult', 'Alcohol Drinking', 'Female', 'Humans', 'Male', 'Problem Behavior', 'Young Adult'] | 30,636,446 | [['M01.060.116'], ['F01.145.317.269'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.126.972', 'F01.145.179.750'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Study on certified reference material of germanium in Ganoderma lucidum]. | Analytical reference material of Ge in Ganoderma lucidum is designed and prepared for accurete analysis, monitoration and evaluation in trades of farming, forestry, medicine and food hygiene for Ge. It is used in technical training, technical assessing, monitoring, data arbitrating and analytic method verifing for prof... | ['Drugs, Chinese Herbal', 'Germanium', 'Reference Standards', 'Reishi'] | 10,682,605 | [['D20.215.784.500.350', 'D26.335'], ['D01.268.513.750', 'D01.268.556.305', 'D01.552.544.305'], ['E05.978.808'], ['B01.300.179.120.760.338.700']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
"Responses to the Chilean law of food labeling and advertising: exploring knowledge, perceptions and behaviors of mothers of young children". | BACKGROUND: In line with calls for action from international health organizations, Chile implemented in June 2016 a set of regulations to tackle the obesity epidemic. The new regulation includes the mandatory use of front-of-package warning labels on packaged foods/beverages high in energy, sugars, saturated fats and s... | ['Adolescent', 'Adult', 'Advertising', 'Child', 'Child, Preschool', 'Chile', 'Feeding Behavior', 'Female', 'Food Labeling', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Mothers'] | 30,760,273 | [['M01.060.057'], ['M01.060.116'], ['J01.219.687.274', 'L01.143.050'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.107.757.235'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['J01.576.423.850.600.400', 'J01.576.761.400.450'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Genetic polymorphism of the kinesin-like protein KIF1B gene and the risk of hepatocellular carcinoma. | BACKGROUND: Frequent deletions of the kinesin-like protein gene 1B (KIF1B) have been reported in neural tumors. Recently, a genome-wide association study revealed an association between polymorphisms in the KIF1B gene and the risk of hepatocellular carcinoma (HCC), and several case-control studies have further investig... | ['Carcinoma, Hepatocellular', 'Cohort Studies', 'Genetic Predisposition to Disease', 'Humans', 'Kinesin', 'Liver Neoplasms', 'Polymorphism, Genetic'] | 23,634,229 | [['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.040.025.193.500', 'D12.776.220.600.450.450', 'D... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Achyranthes bidentata saponins promote osteogenic differentiation of bone marrow stromal cells through the ERK MAPK signaling pathway. | Achyranthes bidentata, is a herbal plant commonly used in the treatment of osteoporosis and bone nonunion in the Traditional Chinese Medicine. Saponins are the major compounds extracted from Achyranthes bidentata that have been shown to exert various pharmacological activities such as anti-inflammatory, antipyretic, an... | ['Achyranthes', 'Alkaline Phosphatase', 'Animals', 'Cell Differentiation', 'Cell Proliferation', 'MAP Kinase Signaling System', 'Male', 'Mesenchymal Stem Cells', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated Protein Kinase 3', 'Osteogenesis', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Saponins', 'Tra... | 24,728,946 | [['B01.650.940.800.575.912.250.198.500.100.100'], ['D08.811.277.352.650.035'], ['B01.050'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['A11.329.830.500', 'A11.872.590.500'], ['D08.811.913.696.620.682.700.567.249.500', 'D12.644.360.450.169.500', 'D12.776.476.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pulsed electromagnetic fields on postmenopausal osteoporosis in Southwest China: a randomized, active-controlled clinical trial. | A randomized, active-controlled clinical trial was conducted to examine the effect of pulsed electromagnetic fields (PEMFs) on women with postmenopausal osteoporosis (PMO) in southwest China. Forty-four participants were randomly assigned to receive alendronate or one course of PEMFs treatment. The primary endpoint was... | ['Aged', 'Bone Density', 'China', 'Electromagnetic Fields', 'Female', 'Humans', 'Magnetic Field Therapy', 'Middle Aged', 'Muscle Strength', 'Osteoporosis, Postmenopausal', 'Postural Balance', 'Vitamin D'] | 23,362,148 | [['M01.060.116.100'], ['G11.427.100'], ['Z01.252.474.164'], ['G01.358.500.260', 'G01.358.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.621'], ['M01.060.116.630'], ['E01.370.600.425', 'G11.427.560'], ['C05.116.198.579.610', 'C18.452.104.579.610'], ['F02.830.816.541.752', 'G07.888.750.500', 'G11.427.6... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Competence check-up. | Revalidation is a new process that requires registered nurses and midwives to demonstrate regularly to the Nursing and Midwifery Council that they remain fit to practise and are competent in their role. | ['Certification', 'Clinical Competence', 'Female', 'Humans', 'Midwifery', 'Nurses', 'Pregnancy', 'United Kingdom'] | 24,617,407 | [['N03.706.110.120', 'N05.700.200.190'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.478.676.416'], ['M01.526.485.650', 'N02.360.650'], ['G08.686.784.769'], ['Z01.542.363']] | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Low calretinin expression and high neutrophil-to-lymphocyte ratio are poor prognostic factors in patients with malignant mesothelioma undergoing extrapleural pneumonectomy. | INTRODUCTION: Survival after extrapleural pneumonectomy (EPP) is variable in patients with malignant pleural mesothelioma (MPM), and there are no validated prognostic factors that could be used preoperatively. We investigated the calretinin and D2-40 expression and the neutrophil-to-lymphocyte ratio (NLR), an index of ... | ['Adult', 'Aged', 'Calbindin 2', 'Female', 'Humans', 'Immunoenzyme Techniques', 'Kaplan-Meier Estimate', 'Lymphocytes', 'Male', 'Mesothelioma', 'Middle Aged', 'Neoplasm Staging', 'Neutrophils', 'Pleural Neoplasms', 'Pneumonectomy', 'Prognosis', 'Retrospective Studies', 'S100 Calcium Binding Protein G', 'Survival Rate',... | 22,011,651 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.157.125.090.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Extracellular vesicles released by mesenchymal-like prostate carcinoma cells modulate EMT state of recipient epithelial-like carcinoma cells through regulation of AR signaling. | Extracellular vesicles released from cancer cells may play an important role in cancer progression by shuttling oncogenic information into recipient cells. However, our knowledge is still fragmentary and there remain numerous questions regarding the mechanisms at play and the functional consequences of these interactio... | ['Androgen Antagonists', 'Antineoplastic Agents, Hormonal', 'Cell Line, Tumor', 'Cell Movement', 'Cell-Derived Microparticles', 'Dose-Response Relationship, Drug', 'Drug Resistance, Neoplasm', 'Epithelial-Mesenchymal Transition', 'Humans', 'Male', 'Neoplasm Invasiveness', 'Neoplasms, Hormone-Dependent', 'Phenotype', 'P... | 28,935,391 | [['D06.347.065', 'D27.505.696.399.450.065'], ['D27.505.954.248.169'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['A11.284.295.588.500'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.984.395'], ['G04.356.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.645', 'C23.5... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diagnostic value of gene probes and its correlation with clinical profile of leprosy in children. | Clinico-bacteriological profile of 73 leprosy patients below 16 years of age was studied. Majority of the patients were males and fell in 11-16 years age group (p < 0.05). Skin lesions were present in all cases on both exposed as well as unexposed areas and their number increased with advancing age. Cutaneous sensation... | ['Adolescent', 'Age Factors', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Incidence', 'India', 'Infant', 'Infant, Newborn', 'Lepromin', 'Leprosy', 'Male', 'Mycobacterium leprae', 'Oligonucleotide Probes'] | 7,875,812 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['Z01.252.245.393'], ['M01.060.703'], ['M01.060.703.520'], ['... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Renal Clearable Ag Nanodots for in Vivo Computer Tomography Imaging and Photothermal Therapy. | Albumin-stabilized Ag nanodots (ANDs) are prepared by a one-step biomineralization method. The highly crystallized nanodots have ultrasmall sizes (approximately 5.8 nm) and robust X-ray attenuation (5.7313 HU per mM Ag). The unlabeled ANDs are directly excreted from the body via the urine after in vivo X-ray computer t... | ['Humans', 'Nanostructures', 'Neoplasms', 'Phototherapy', 'Silver', 'Theranostic Nanomedicine', 'Tomography, X-Ray Computed'] | 28,111,943 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.637.512'], ['C04'], ['E02.774'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.544.812'], ['E01.894', 'E02.785.500', 'E02.921', 'H01.603.600.500', 'H02.403.200.700.500', 'H02.403.845', 'J01.897.520.600.600.500'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
REMAS: a new regression model to identify alternative splicing events from exon array data. | BACKGROUND: Alternative splicing (AS) is an important regulatory mechanism for gene expression and protein diversity in eukaryotes. Previous studies have demonstrated that it can be causative for, or specific to splicing-related diseases. Understanding the regulation of AS will be helpful for diagnostic efforts and dru... | ['Algorithms', 'Alternative Splicing', 'Exons', 'Linear Models', 'Oligonucleotide Array Sequence Analysis'] | 19,208,117 | [['G17.035', 'L01.224.050'], ['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['G05.360.340.024.340.137.232'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['E05.393.661.64... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
In Vivo Characterization of Carotid Neointimal Hyperplasia by use of Optical Coherence Tomography: Before and After Cutting Balloon Angioplasty. | Optical coherence tomography (OCT) is a modern intravascular imaging modality that has the capability to provide detailed, in vivo characterization of the arterial wall and atherosclerotic plaque. The current understanding of the appearance of atherosclerotic plaque via OCT is largely based on coronary arterial studies... | ['Aged', 'Angioplasty, Balloon', 'Carotid Artery Diseases', 'Humans', 'Hyperplasia', 'Male', 'Plaque, Atherosclerotic', 'Tomography, Optical Coherence', 'Treatment Outcome'] | 25,702,776 | [['M01.060.116.100'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['C10.228.140.300.200', 'C14.907.253.123'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['C23.300.823'], ['E01.370.350.589.249.500', 'E01.370.350.825.805.500', 'E05.642.249.500'], ['E01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inhibition of tristetraprolin expression by dexamethasone in activated macrophages. | Tristetraprolin (TTP) is a factor that regulates mRNA stability and the expression of certain inflammatory genes. In the present study, we found that TTP expression was increased in macrophages exposed to bacterial lipopolysaccharide (LPS). Dexamethasone and dissociated steroid RU24858 inhibited LPS-induced TTP protein... | ['Animals', 'Cell Line', 'DNA-Binding Proteins', 'Desoximetasone', 'Dexamethasone', 'Gene Expression Regulation', 'Histone Deacetylases', 'Hydroxycorticosteroids', 'Immediate-Early Proteins', 'Lipopolysaccharides', 'Macrophage Activation', 'Macrophages', 'Mice', 'RNA, Messenger', 'Tristetraprolin'] | 15,710,351 | [['B01.050'], ['A11.251.210'], ['D12.776.260'], ['D04.210.500.745.432.719.260', 'D04.210.500.908.238.250'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['G05.308'], ['D08.811.277.087.520'], ['D06.472.040.585'], ['D12.776.460', 'D12.776.964.925.968'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.16... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical management of eosinophilic esophagitis - a nationwide survey among gastroenterologists in Germany. | BACKGROUND: Eosinophilic esophagitis (EoE) is an increasingly recognized immune-mediated esophageal disease and a common cause for dysphagia and food bolus obstruction. The aim of this study was to evaluate the current clinical management of EoE among adult gastroenterologists in Germany.METHODS: We performed a cross... | ['Adult', 'Cross-Sectional Studies', 'Diet Therapy', 'Eosinophilic Esophagitis', 'Gastroenterologists', 'Gastroenterology', 'Germany', 'Glucocorticoids', 'Guideline Adherence', 'Humans', 'Practice Guidelines as Topic', "Practice Patterns, Physicians'", 'Proton Pump Inhibitors', 'Surveys and Questionnaires'] | 31,170,743 | [['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E02.642.249'], ['C06.405.117.620.209', 'C06.405.205.663.209', 'C15.378.553.231.341', 'C20.543.480.356'], ['M01.526.485.810.438', 'N02.360.810.438'], ['H02.403.429.405'], ['Z01.542.315'], ['D06.472.040.543', 'D27.505.696.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Evolutionary aspects of trypanosomes: analysis of genes. | The genes for four glycolytic enzymes of Trypanosoma brucei have been analyzed. The proteins encoded by these genes show 38-57% identity with their counterparts in other organisms, whether pro- or eukaryotic. These data are consistent with a phylogenetic tree in which trypanosomes diverged very early from the main bran... | ['Animals', 'Biological Evolution', 'Codon', 'Fructose-Bisphosphate Aldolase', 'Genes', 'Glyceraldehyde-3-Phosphate Dehydrogenases', 'Glycoproteins', 'Humans', 'Phosphoglycerate Kinase', 'Species Specificity', 'Triose-Phosphate Isomerase', 'Trypanosoma brucei brucei', 'Variant Surface Glycoproteins, Trypanosoma'] | 3,104,618 | [['B01.050'], ['G05.045', 'G16.075'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['D08.811.520.224.062.400'], ['G05.360.340.024.340'], ['D08.811.682.657.163.750'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.630.700'], ['G16.824'], [... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessment and confirmation of tracheal intubation when capnography fails: a novel use for an USB camera. | A 62 year old male with a right pyriform fossa lesion extending to the right arytenoid and obscuring the glottic inlet was planned for laser assisted excision. Direct laryngoscopic assessment after topicalization of the airway, showed a Cormack Lehane grade 3 view. We report a case where, in the absence of a fiberscope... | ['Capnography', 'Humans', 'Hypopharyngeal Neoplasms', 'Intubation, Intratracheal', 'Laryngoscopy', 'Male', 'Middle Aged', 'Photography', 'Signal Processing, Computer-Assisted', 'Treatment Outcome', 'Video Recording'] | 23,536,203 | [['E01.370.386.700.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.710.485', 'C07.550.745.436', 'C09.647.710.485', 'C09.775.549.485'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['E01.370.386.460', 'E01.370.388.250.525', 'E04.502.250.525', 'E04.580.373'], ['M01.060.116.630'], ['E01.370.350... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Body Mass Index (BMI), BMI Change, and Overall Survival in Patients With SCLC and NSCLC: A Pooled Analysis of the International Lung Cancer Consortium. | INTRODUCTION: The relationships between morbid obesity, changes in body mass index (BMI) before cancer diagnosis, and lung cancer outcomes by histology (SCLC and NSCLC) have not been well studied.METHODS: Individual level data analysis was performed on 25,430 patients with NSCLC and 2787 patients with SCLC from 16 stud... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Body Mass Index', 'Carcinoma, Non-Small-Cell Lung', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Risk Factors', 'Small Cell Lung Carcinoma', 'Survival Analysis', 'Young Adult'] | 31,163,278 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Correlates of environmental factors and human plague: an ecological study in Vietnam. | BACKGROUND: Human plague caused by Yersinia pestis remains a public health threat in endemic countries, because the disease is associated with increased risk of mortality and severe economic and social consequences. During the past 10 years, outbreaks of plague have occasionally occurred in Vietnam's Central Highlands ... | ['Animals', 'Disease Outbreaks', 'Disease Reservoirs', 'Humans', 'Incidence', 'Insect Vectors', 'Plague', 'Population Density', 'Population Growth', 'Rain', 'Risk Factors', 'Rodentia', 'Seasons', 'Sentinel Surveillance', 'Siphonaptera', 'Vietnam', 'Yersinia pestis', 'Zoonoses'] | 19,584,125 | [['B01.050'], ['N06.850.290'], ['N06.850.520.203.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['C01.150.252.400.310.980.390', 'C01.920.... | ['Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Ileal pouch functional outlet obstruction. | Small bowel obstructions (SBOs) are common in patients who have undergone Ileal J-pouch-anal anastomosis (IPAA) surgery. SBO may be caused by stenosis of the diverting ileostomy, volvulus, internal hernia, adhesive bands, anastomotic stricture or intra-abdominal adhesions. Functional outlet obstruction is an important ... | ['Adult', 'Colonic Pouches', 'Diagnosis, Differential', 'Female', 'Humans', 'Ileostomy', 'Intestinal Obstruction', 'Intestine, Small'] | 26,857,583 | [['M01.060.116'], ['A10.850.200', 'E07.862.200'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.210.338.508', 'E04.579.338.508'], ['C06.405.469.531'], ['A03.556.124.684']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
L-pipecolic acid oxidation in rat: subcellular localization and developmental study. | By using a sensitive radioactive assay method, we present here evidence that L-pipecolic acid oxidase is localized in both mitochondria and peroxisomes of rat liver. Brain white matter contained a more than 2-fold higher activity of L-pipecolic acid oxidation than the brain cortex. Suborganellar fractionation studies i... | ['Aging', 'Animals', 'Antimycin A', 'Brain', 'Diethylhexyl Phthalate', 'Enzyme Induction', 'Glucagon', 'Liver', 'Male', 'Oxidoreductases Acting on CH-NH Group Donors', 'Rats', 'Rats, Sprague-Dawley', 'Rotenone', 'Subcellular Fractions'] | 8,518,295 | [['G07.345.124'], ['B01.050'], ['D02.540.576.500.750'], ['A08.186.211'], ['D02.241.223.805.250'], ['G05.308.320.200'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['A03.620'], ['D08.811.682.662'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['D03.383.663.283... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Blood inflammatory response to inhaled endotoxin in normal subjects. | Previously we have reported that in asthmatics an inhalation of 20 micrograms lipopolysaccharide (LPS) produces a bronchial obstruction associated with an inflammatory blood response. The aim of the present study was to evaluate this response in normal subjects. Eight normal non-atopic subjects were challenged by inhal... | ['Administration, Inhalation', 'Adrenocorticotropic Hormone', 'Adult', 'C-Reactive Protein', 'Endotoxins', 'Escherichia coli', 'Female', 'Forced Expiratory Volume', 'Humans', 'Leukocyte Count', 'Lipopolysaccharides', 'Lung', 'Male', 'Neutrophil Activation', 'Respiratory Hypersensitivity', 'Single-Blind Method'] | 7,728,626 | [['E02.319.267.050'], ['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['M01.060.116'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['D23.946.123.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Economic and non-economic determinants of Iranian pharmaceutical companies' financial performance: an empirical study. | BACKGROUND: The pharmaceutical industry in Iran is influenced by various parameters such as internal factors caused by the financial information of each economic unit and external factors including major economic and non-economic variables.METHODS: This study is aiming to examine the effect of such variables on the sto... | ['Drug Industry', 'Empirical Research', 'Gross Domestic Product', 'Health Care Costs', 'Health Care Sector', 'Humans', 'Iran'] | 31,888,627 | [['J01.576.655.750'], ['H01.770.644.241'], ['I01.261.587'], ['N03.219.151.400', 'N05.300.375'], ['J01.576.489', 'N03.219.650'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.350']] | ['Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
Comparison of Surgeon Assessment to Frailty Measurement in Abdominal Aortic Aneurysm Repair. | BACKGROUND: Endovascular abdominal aortic aneurysm repair (EVAR) allows us to intervene on patients otherwise considered poor candidates for open repair. Despite its importance in determining operative approach, no comparison has been made between the subjective "eyeball test" and an objective measurement of preoperati... | ['Aged', 'Aged, 80 and over', 'Aortic Aneurysm, Abdominal', 'Endovascular Procedures', 'Female', 'Frailty', 'Humans', 'Male', 'North America', 'Retrospective Studies', 'Risk Assessment'] | 31,841,735 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['E04.100.814.529', 'E04.502.382'], ['C23.550.359'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Value of C-reactive protein in the evaluation of activity in ulcerative colitis and Crohn's disease]. | We studied a value of measuring the C-reactive protein (CRP) serum concentration in the assessment of ulcerative colitis and Crohn's disease activity. From a large register of patients with the inflammatory bowel disease (IBD), we have chosen randomly 91 patients: 61 with ulcerative colitis and 30 with Crohn's disease.... | ['C-Reactive Protein', 'Colitis, Ulcerative', 'Crohn Disease', 'Humans'] | 2,093,781 | [['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['C06.405.205.265.231', 'C06.405.205.731.249', 'C06.405.469.158.188.231', 'C06.405.469.432.249'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ethnic differences in the soft tissue profile of Korean and European-American adults with normal occlusions and well-balanced faces. | Orthodontic diagnosis typically includes comparing a patient's cephalometric measurements to standard values. Lateral cephalometric norms, however, may be specific to an ethnic group and cannot always be applied to other ethnic types. The purpose of this study was to compare the soft tissue profiles obtained from Korea... | ['Adolescent', 'Adult', 'Asian Continental Ancestry Group', 'Cephalometry', 'Chin', 'Europe', 'European Continental Ancestry Group', 'Face', 'Female', 'Humans', 'Korea', 'Lip', 'Male', 'Nose', 'Reference Values', 'Sex Characteristics', 'United States'] | 11,843,277 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.200'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['A01.456.505.259', 'A02.835.232.781.324.502.632.130', 'A14.521.632.300'], ['Z01.542'], ['M01.686.508.400'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.557', 'Z... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Major revision of the allergen database for food safety (ADFS) and validation of the motif-based allergenicity prediction tool]. | We have been maintaining an integral web server system, the Allergen Database for Food Safety (ADFS), since 2005 (http://allergen.nihs.go.jp/ADFS/). Recently, a group at the University of Nebraska-Lincoln released a new version of an allergen database, AllergenOnline. This database includes more than 1,300 allergens, a... | ['Allergens', 'Amino Acid Motifs', 'Databases, Protein', 'Food', 'Food Hypersensitivity', 'Forecasting', 'Humans'] | 20,306,706 | [['D23.050.063'], ['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['G07.203.300', 'J02.500'], ['C20.543.480.370'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 |
Changes in mitochondrial morphology and organization can enhance energy supply from mitochondrial oxidative phosphorylation in diabetic cardiomyopathy. | Diabetic cardiomyopathy is accompanied by metabolic and ultrastructural alterations, but the impact of the structural changes on metabolism itself is yet to be determined. Morphometric analysis of mitochondrial shape and spatial organization within transverse sections of cardiomyocytes from control and streptozotocin-i... | ['Adenosine Triphosphate', 'Animals', 'Cell Size', 'Cells, Cultured', 'Computer Simulation', 'Diabetic Cardiomyopathies', 'Mitochondria, Heart', 'Models, Cardiovascular', 'Oxidative Phosphorylation', 'Rats', 'Rats, Sprague-Dawley'] | 27,903,587 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['G04.325'], ['A11.251'], ['L01.224.160'], ['C14.280.238.235', 'C19.246.099.625'], ['A11.284.430.214.190.875.564.627.603', 'A11.284.835.626.627.603'], ['E05.599.395.161'], ['G02.111.665.550', 'G03.295.631', 'G03.796.550'], ['B0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Evaluation of use of proton pump inhibitors in Greece. | INTRODUCTION: Proton pump inhibitors (PPIs) are widely used for acid-related gastric diseases. However, several national studies reported increasing use of PPIs for yet unlicensed indications.AIM: The aim of our study was to evaluate the extent of PPIs prescription in a Greek tertiary hospital, as well as the adherence... | ['Adult', 'Anti-Inflammatory Agents, Non-Steroidal', 'Drug Prescriptions', 'Drug Utilization', 'Gastroesophageal Reflux', 'Greece', 'Helicobacter Infections', 'Helicobacter pylori', 'Humans', 'Omeprazole', 'Peptic Ulcer', "Practice Patterns, Physicians'", 'Proton Pump Inhibitors', 'Retrospective Studies', 'Stomach Dise... | 19,327,607 | [['M01.060.116'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['E02.319.307', 'N02.421.668.778.500'], ['N04.452.706.477'], ['C06.405.117.119.500.484'], ['Z01.542.383'], ['C01.150.252.400.466'], ['B03.440.500.550', 'B03.660.150.235.500.250.550'], ['B01.050.150.900.649.313.988.400.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Efficacy of continuous irrigation combined with closed thoracic drainage for esophagojejunal anastomotic fistula complicated with mediastinal, thoracic and abdominal infections]. | OBJECTIVE: To investigate the clinical efficacy of continuous irrigation combined with closed thoracic drainage for esophagojejunal anastomotic fistula (EJAF) complicated with mediastinal, thoracic and abdominal infection after total gastrectomy.METHODS: Clinical data of 22 EJAF patients complicated with mediastinal, t... | ['Aged', 'Anastomosis, Surgical', 'Bacterial Infections', 'Digestive System Fistula', 'Drainage', 'Gastrectomy', 'Humans', 'Laparoscopy', 'Male', 'Middle Aged', 'Postoperative Complications', 'Retrospective Studies', 'Therapeutic Irrigation'] | 30,588,589 | [['M01.060.116.100'], ['E04.035'], ['C01.150.252'], ['C06.267', 'C23.300.575.185'], ['E02.309', 'E04.237'], ['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630'], ['C23.550.767'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Increased hepatic ABCA1 transporter is associated with hypercholesterolemia in a cholestatic rat model and primary biliary cholangitis patients. | Hepatic ATP-binding cassette A1 (ABCA1) transporter is the modulator of intrahepatic cholesterol levels via the efflux of cholesterol into plasma. This study aimed to determine the expression of hepatic ABCA1 levels in a cholestatic rat model and patients with primary biliary cholangitis (PBC). A cholesterol efflux stu... | ['ATP Binding Cassette Transporter 1', 'Animals', 'Biological Transport', 'Cell Line, Tumor', 'Cholestasis, Intrahepatic', 'Cholesterol', 'Disease Models, Animal', 'Gene Expression Regulation', 'Hepatocytes', 'Humans', 'Hypercholesterolemia', 'Liver', 'Liver Cirrhosis, Biliary', 'Liver X Receptors', 'Male', 'RNA, Messe... | 28,660,384 | [['D12.776.157.530.100.050.500', 'D12.776.395.550.020.381.500', 'D12.776.543.550.192.381.500', 'D12.776.543.585.100.190.500'], ['B01.050'], ['G03.143'], ['A11.251.210.190', 'A11.251.860.180'], ['C06.130.120.135.250', 'C06.552.150'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['C22.232', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hepatitis C virus NS5A-regulated gene expression and signaling revealed via microarray and comparative promoter analyses. | Most individuals exposed to hepatitis C virus (HCV) become chronically infected and are predisposed to liver disease. The mechanisms underlying viral persistence and disease progression are unknown. A role for the HCV NS5A protein in viral replication and interferon resistance has been demonstrated. To identify mechani... | ['Amino Acid Sequence', 'Binding Sites', 'Calcium', 'Carcinoma, Hepatocellular', 'Carrier Proteins', 'Gene Expression Profiling', 'Gene Expression Regulation, Viral', 'Hepatitis C', 'Humans', 'Interferon-alpha', 'Interleukin-1', 'Intracellular Signaling Peptides and Proteins', 'Latent TGF-beta Binding Proteins', 'Lipid... | 15,349,911 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['D12.776.157'], ['E05.393.332'], ['G05.308.385'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.35... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Use of preoperative magnetic resonance imaging for invasive lobular cancer: good, better, but maybe not the best? | BACKGROUND: Invasive lobular cancer (ILC) of the breast is difficult to diagnose clinically and radiologically. It is hoped that preoperative magnetic resonance imaging (MRI) can improve evaluation of extent of disease.METHODS: Patients diagnosed with ILC at a single institution from 2001 to 2008 who underwent clinical... | ['Adult', 'Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Carcinoma, Lobular', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Mammography', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Staging', 'Preoperative Care', 'Prognosis', 'Prospective Studies', 'Retrospective Studies', 'Se... | 20,853,043 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['C04.557.470.200.025.305', 'C04.557.470.615.305', 'C04.588.180.437', 'C17.800.090.500.437'], ['B01.050.150.900.649.31... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Determination of the effect of acetylation of specific lysine residues in human growth hormone on its affinity for somatogenic receptors by an affinity selection technique. | A technique is described to study the effect of acetylation of individual lysine residues in peptide hormones on the affinity for their receptors, and is illustrated for the case of human growth hormone (hGH) binding to somatogenic receptors. The hGH was partially acetylated with high specific activity [3H]-acetic anhy... | ['Acetylation', 'Animals', 'Chromatography, Gel', 'Chromatography, High Pressure Liquid', 'Chromatography, Ion Exchange', 'Growth Hormone', 'Humans', 'Liver', 'Lysine', 'Male', 'Peptide Fragments', 'Rats', 'Receptors, Somatotropin', 'Trypsin'] | 3,122,756 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['B01.050'], ['E05.196.181.400.250'], ['E05.196.181.400.300'], ['E05.196.181.400.383'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'],... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Delayed cerebrospinal-fluid shunt infection in children. | Twelve patients with shunt infection occurring more than 6 months following shunt implantation or revision were identified and their charts reviewed. These cases were accumulated over a 9-year period, and delays from shunt surgery to detection were as long as 11 years. For 5 patients, no antecedent infection or surgery... | ['Adolescent', 'Bacteria', 'Bacterial Infections', 'Bacterial Physiological Phenomena', 'Cerebrospinal Fluid Shunts', 'Child', 'Female', 'Heart Atria', 'Humans', 'Infant', 'Male', 'North Carolina', 'Peritoneum', 'Postoperative Complications', 'Retrospective Studies', 'Time Factors'] | 2,702,349 | [['M01.060.057'], ['B03'], ['C01.150.252'], ['G06.099'], ['E04.035.188', 'E04.525.170'], ['M01.060.406'], ['A07.541.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['Z01.107.567.875.075.475', 'Z01.107.567.875.750.530'], ['A01.923.047.025.600', 'A10.615.789.596'], ['C23.550.767'], ['E05.318.372.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Geographicals [Z]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Marek's disease vaccines. | Marek's disease (MD) vaccines have been in almost universal use since the early 1970's and constitute the first effective practical means for the control of any neoplastic disease in man or animals. Five types have been described: 1) attenuated variants of oncogenic strains (Serotype 1) of Marek's disease virus (MDV) p... | ['Animals', 'Antibody Formation', 'Antigens, Viral', 'Birds', 'Herpesvirus 2, Gallid', 'Immunity, Cellular', 'Marek Disease', 'Vaccines, Attenuated', 'Viral Vaccines'] | 6,299,850 | [['B01.050'], ['G12.450.050.370.250'], ['D23.050.327'], ['B01.050.150.900.248'], ['B04.280.382.100.562.400'], ['G12.450.050.400'], ['C01.925.256.466.650', 'C01.925.928.489', 'C15.604.515.700', 'C20.683.515.840', 'C22.131.546'], ['D20.215.894.811'], ['D20.215.894.899']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-resolution magic angle spinning NMR studies for metabolic characterization of Arabidopsis thaliana mutants with enhanced growth characteristics. | Developing smart crops which yield more biomass to meet the increasing demand for plant biomass has been an active area of research in last few decades. We investigated metabolic alterations in two Arabidopsis thaliana mutants with enhanced growth characteristics that were previously obtained from a collection of plant... | ['Arabidopsis', 'Magnetic Resonance Spectroscopy', 'Metabolome', 'Metabolomics', 'Models, Biological', 'Phenotype', 'Plant Development'] | 30,596,736 | [['B01.650.940.800.575.912.250.157.100'], ['E05.196.867.519'], ['G03.500'], ['H01.158.201.586', 'H01.158.273.180.599', 'H01.181.122.638'], ['E05.599.395'], ['G05.695'], ['G07.345.625', 'G15.589']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Wolf's isotopic response: rosacea appearing at the site of healed herpes zoster. | A 40-year-old man developed an erythematous rash on the right side of his face 3 weeks after a herpes zoster infection at the same location. Examination revealed an erythematous papular eruption and telangiectasias along the ophthalmic and maxillary divisions of the right trigeminal nerve, exactly at the site of the co... | ['Adult', 'Face', 'Herpes Zoster', 'Humans', 'Isotretinoin', 'Male', 'Rosacea', 'Treatment Outcome'] | 16,867,001 | [['M01.060.116'], ['A01.456.505'], ['C01.925.256.466.930.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.326.271.665.202.495.325', 'D02.455.426.392.368.367.379.249.700.325', 'D02.455.849.131.495.325', 'D23.767.261.700.325'], ['C17.800.716'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Religious predictors of cigarette smoking: findings for African American women of childbearing age. | Data from a community-based survey of 252 African American women 18 to 44 years of age were used to examine the relation between cigarette smoking and two measures of religious involvement. Findings indicated that cigarette smoking among African American women of childbearing age is related to their denominational affi... | ['Adolescent', 'Adult', 'African Americans', 'Age Factors', 'Educational Status', 'Female', 'Humans', 'Prevalence', 'Probability', 'Religion', 'Smoking', 'Stress, Psychological', 'United States', "Women's Health"] | 7,919,633 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['N05.715.350.075', 'N06.850.490.250'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['E05.318.740.600', '... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Humanities [K]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Comparison of inhalation-to-perfusion ratio in anesthetized dogs with barrel-shaped thorax vs dogs with deep thorax. | Interregional, as well as intraregional (local), distributions of the inhalation-to-perfusion ratio were analyzed in the lungs of 20 prone anesthetized healthy dogs--10 dogs with barrel-shaped thorax (Beagles) and 10 dogs with deep thorax (Greyhound-type dogs)--using 99mTc inhalation-perfusion lung scintigraphy. Dorsov... | ['Aerosols', 'Animals', 'Breeding', 'Dogs', 'Female', 'Lung', 'Male', 'Radionuclide Imaging', 'Thorax', 'Ventilation-Perfusion Ratio'] | 1,892,263 | [['D20.280.055', 'D26.255.165.055'], ['B01.050'], ['E05.820.150', 'G05.090'], ['B01.050.150.900.649.313.750.250.216.200'], ['A04.411'], ['E01.370.350.710', 'E01.370.384.730'], ['A01.923.761'], ['E01.370.386.700.650.900', 'G09.772.920']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sedimentation by gravity stabilizes plasma glucose for up to 60 minutes. | OBJECTIVE: Glucose levels decrease in whole blood in vitro, but there are several methods that minimize the loss, including special tubes and ice. This study evaluated whether sedimentation by gravity in an upright position was a viable alternative.DESIGN: Lithium heparinized blood was collected from 20 individuals wit... | ['Anticoagulants', 'Blood Chemical Analysis', 'Blood Glucose', 'Blood Specimen Collection', 'Gravitation', 'Heparin', 'Humans'] | 23,967,545 | [['D27.505.954.502.119'], ['E01.370.225.124.100', 'E05.200.124.100'], ['D09.947.875.359.448.500'], ['E01.370.225.998.110', 'E04.665.150', 'E05.200.998.110'], ['G01.060.350'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Organization of amphiphiles: XII. Evidence in favor of formation of hydrophobic complexes in aqueous solution. | The effects of nonionic surfactants OP-10 and OP-30 (polyoxyethylated octyl phenols with 10 and 30 oxyethylene groups, respectively) in surfactant mixtures with ionic surfactants hexadecyltrimethylammonium bromide (CTAB) and sodium dodecyl sulphate (SDS) have been investigated by a conductometric method in conjunction ... | ['Hydrophobic and Hydrophilic Interactions', 'Micelles', 'Molecular Structure', 'Particle Size', 'Polyethylene Glycols', 'Surface-Active Agents', 'Thermodynamics', 'Water'] | 21,396,651 | [['G02.409'], ['D05.374', 'D26.255.560'], ['G02.111.570', 'G02.466'], ['G02.712'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['D27.720.877'], ['G01.906'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The case of Claire Conroy: will administrative review safeguard incompetent patients? | The emotional issue of withdrawing feeding tubes from incompetent patients was reviewed recently by the New Jersey Supreme Court in the case of Claire Conroy. The court ruled that artificial feedings do not differ from other life-sustaining treatments and may be withdrawn or withheld if they are against the patient's w... | ['Aged', 'Dementia', 'Enteral Nutrition', 'Ethics Committees, Clinical', 'Euthanasia', 'Euthanasia, Passive', 'Family', 'Female', 'Government', 'Humans', 'Life Support Care', 'New Jersey', 'Nursing Homes', 'Patient Advocacy', 'Physicians', 'Withholding Treatment'] | 3,085,567 | [['M01.060.116.100'], ['C10.228.140.380', 'F03.615.400'], ['E02.421.360', 'E02.642.500.360'], ['K01.752.566.479.147.500', 'N04.452.758.788.300.500', 'N05.350.268.500', 'N05.700.685.300.500'], ['E02.760.905.199', 'I01.880.735.344.500', 'N02.421.585.905.199'], ['E02.760.905.199.500', 'E02.760.952.500', 'N02.421.585.905.1... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Quantitative determination of trimebutine maleate and its three metabolites in human plasma by liquid chromatography-tandem mass spectrometry. | A sensitive and selective HPLC-MS-MS method was developed for the determination of trimebutine maleate (TM) and its major metabolites N-monodemethyltrimebutine (TM-MPB), N-didemethyltrimebutine (APB) and 3,4,5-trimethoxybenzoic acid (TMBA) in human plasma. The analytes were extracted from plasma samples by liquid-liqui... | ['Chromatography, High Pressure Liquid', 'Gastrointestinal Agents', 'Humans', 'Mass Spectrometry', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Trimebutine'] | 12,361,732 | [['E05.196.181.400.300'], ['D27.505.954.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Successful Treatment of Recalcitrant Prurigo with Alitretinoin. | BACKGROUND: Chronic itch with secondary scratch lesions such as prurigo has a major impact on quality of life. Due to its relapsing nature and often unknown origin, its treatment is challenging.OBJECTIVE: We sought to demonstrate that alitretinoin can be an efficacious and well-tolerated treatment in a patient sufferin... | ['Alitretinoin', 'Antineoplastic Agents', 'Female', 'Humans', 'Middle Aged', 'Prurigo', 'Pruritus', 'Psoriasis', 'Retreatment', 'Tretinoin'] | 26,304,762 | [['D02.455.326.271.665.202.495.818.500.500', 'D02.455.426.392.368.367.379.249.700.860.500.500', 'D02.455.849.131.495.818.800.500', 'D02.455.849.291.925.500.500', 'D23.767.261.700.780.500'], ['D27.505.954.248'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C17.800.674'], ['C17.800.685', 'C23.8... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ghrelin Octanoylation Is Completely Stabilized in Biological Samples by Alkyl Fluorophosphonates. | Ghrelin is a peptide hormone involved in multiple physiological processes related to energy homeostasis. This hormone features a unique posttranslational serine octanoylation modification catalyzed by the enzyme ghrelin O-acyltransferase, with serine octanoylation essential for ghrelin to bind and activate its cognate ... | ['Acylation', 'Acyltransferases', 'Animals', 'Fluorides', 'Ghrelin', 'HEK293 Cells', 'Humans', 'Male', 'Phosphates', 'Protein Stability', 'Rats', 'Rats, Wistar', 'Serine'] | 27,623,288 | [['G02.111.012', 'G02.607.063', 'G03.040'], ['D08.811.913.050'], ['B01.050'], ['D01.248.497.158.380', 'D01.303.350.300'], ['D06.472.699.301', 'D12.644.548.322'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.695.625.675.6... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Knowledge and attitudes about urinary incontinence among community-dwelling Korean American women. | PURPOSE: The purpose of this study was to explore knowledge and attitudes about urinary incontinence (UI) among Korean American women with incontinence and provide initial information needed to design education programs and culture-specific interventions.SUBJECTS AND SETTING: One hundred eighty-two community-dwelling K... | ['Adult', 'Analysis of Variance', 'Arizona', 'Asian Americans', 'Attitude to Health', 'Cross-Sectional Studies', 'Cultural Competency', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Korea', 'Middle Aged', 'Needs Assessment', "Nurse's Role", 'Nursing Methodology Research', 'Patient Education as Topic', '... | 19,287,269 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['Z01.107.567.875.760.100'], ['M01.686.508.200.100', 'M01.686.754.225'], ['F01.100.150', 'N05.300.150'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.880.853.100.364'], ['F01.100.150.500', 'N05.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Nucleoporin-Regulated MAP Kinase Signaling in Immunity to a Necrotrophic Fungal Pathogen. | Pathogen-responsive mitogen-activated protein kinase (MAPK or MPK) cascades relay signals from activated immune receptors across the nuclear envelope to intranuclear targets. However, in plants, little is known about the spatial control of MAPK signaling. Here, we report that the Arabidopsis (Arabidopsis thaliana) nucl... | ['Active Transport, Cell Nucleus', 'Arabidopsis', 'Arabidopsis Proteins', 'Botrytis', 'Disease Resistance', 'Gene Expression Regulation, Plant', 'Host-Pathogen Interactions', 'Immunoblotting', 'MAP Kinase Signaling System', 'Microscopy, Confocal', 'Mitogen-Activated Protein Kinase Kinases', 'Mitogen-Activated Protein K... | 27,591,188 | [['G03.143.310.100', 'G03.143.700.100'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['B01.300.381.128'], ['C23.550.291.671', 'G12.450.564.250', 'G12.450.800.250', 'G15.630.250'], ['G05.308.375'], ['G06.462', 'G16.527.200'], ['E05.478.566.320', 'E05.601.470.320'], ['G02.111.820.560', 'G03.493.560', 'G... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tryptophan super-repressors with alanine 77 changes. | The binding of L-tryptophan to Escherichia coli tryptophan aporepressor enables the holorepressor complex to bind operator DNA tightly. The side chain of residue alanine 77 is located in one of the most flexible regions of Trp repressor, between residues critical for binding DNA. Codon-directed mutagenesis was used to ... | ['Alanine', 'Amino Acid Sequence', 'Apoproteins', 'Bacterial Proteins', 'Base Sequence', 'DNA, Bacterial', 'Escherichia coli', 'Escherichia coli Proteins', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Repressor Proteins', 'Tryptophan'] | 8,440,721 | [['D12.125.042'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.070'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.212'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['L01.453.245.667'], ['E05.393.420.601.575'], ['D12.776.260.703', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
New method for the accurate characterization of single human skeletal muscle fibres demonstrates a relation between mATPase and MyHC expression in pure and hybrid fibre types. | In the present study we have developed a method which, by combining histochemical, immunohistochemical, electrophoretic and immunoblotting analyses on a single fibre, enables a sensitive characterization of human skeletal muscle fibres dissected from freeze-dried biopsy samples. For histochemical (and immunohistochemic... | ['Animals', 'Antibodies, Monoclonal', 'Biopsy, Needle', 'Blotting, Western', 'Electrophoresis, Polyacrylamide Gel', 'Freeze Drying', 'Gene Expression', 'Humans', 'Image Processing, Computer-Assisted', 'Immunoenzyme Techniques', 'Mice', 'Mice, Inbred BALB C', 'Muscle Fibers, Skeletal', 'Myosins', 'Rabbits', 'Specimen Ha... | 7,751,402 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['E05.196.401.143', 'E05.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Explaining variations in inpatient length of stay in the National Health Service. | This paper seeks to explain variations in acute inpatient length of stay in the National Health Service in England. A model is proposed in which the length of stay is allowed to vary according to patient characteristics, the local supply of NHS care. the local pressure on NHS resources, other non-NHS health care supply... | ['Analysis of Variance', 'Efficiency, Organizational', 'England', 'Health Services Accessibility', 'Health Services Research', 'Hospitals, Public', 'Humans', 'Least-Squares Analysis', 'Length of Stay', 'Models, Statistical', 'Socioeconomic Factors', 'State Medicine', 'United Kingdom', 'Waiting Lists'] | 10,159,443 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['N04.452.209.500'], ['Z01.542.363.300'], ['N04.590.374.350', 'N05.300.430'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['N02.278.421.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.750.400', 'N05.715.360.750.695.440', 'N... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
MRI measurement of hepatic magnetic susceptibility-phantom validation and normal subject studies. | A magnetic resonance (MR) imaging method with the potential for assessing hepatic iron overload from measurements of hepatic magnetic susceptibility in vivo is described. Using the blood in the portal and hepatic veins as an internal reference, this technique uses the orientation dependence of signal phase to measure t... | ['Algorithms', 'Computer Simulation', 'Humans', 'Iron Overload', 'Liver', 'Magnetic Resonance Imaging', 'Phantoms, Imaging', 'Reproducibility of Results'] | 15,562,494 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.565.500'], ['A03.620'], ['E01.370.350.825.500'], ['E07.671'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Synthesis, characterization, biological evaluation and docking studies of macrocyclic binuclear manganese(II) complexes containing 3,5-dinitrobenzoyl pendant arms. | A series of bis(phenoxo) bridged binuclear manganese(II) complexes of the type [Mn2L(1-3)](ClO4)2 (1-3) containing 3,5-dinitrobenzoyl pendant-arms have been synthesized by cyclocondensation of 2,6-diformyl-4-R-phenols (where R=CH3, C(CH3)3 or Br) with 2,2'-3,5-dinitrobenzoyliminodi(ethylamine) trihydrochloride in the p... | ['Anti-Bacterial Agents', 'Coordination Complexes', 'DNA Cleavage', 'Dinitrobenzenes', 'ErbB Receptors', 'Gram-Negative Bacteria', 'Gram-Positive Bacteria', 'Intercalating Agents', 'Manganese', 'Molecular Docking Simulation'] | 25,710,114 | [['D27.505.954.122.085'], ['D01.234', 'D02.257'], ['G02.111.210', 'G05.193'], ['D02.455.426.559.389.565.225', 'D02.640.529.240'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['B03.440'], ['B03.510'], ['D27.720.470.410.360'], ['D01.268.556.484', 'D01.268.956.374', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Prelining of polytetrafluoroethylene grafts with cultured human endothelial cells isolated from varicose veins. | Prelining graft material with autologous functioning endothelial cells might be one of the ultimate requirements to obtain a biocompatible surface. Accordingly, endothelial cells from stripped varicose veins were enzymatically harvested and grown on a fibronectin matrix. Proliferation was investigated in defined medium... | ['Adult', 'Blood Vessel Prosthesis', 'Cell Adhesion', 'Cell Division', 'Cell Separation', 'Cells, Cultured', 'Cold Temperature', 'Cytological Techniques', 'Endothelium, Vascular', 'Heparin', 'Humans', 'Microscopy, Electron, Scanning', 'Polytetrafluoroethylene', 'Preservation, Biological', 'Saphenous Vein', 'Varicose Ve... | 2,643,196 | [['M01.060.116'], ['E07.695.110'], ['G04.022'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['A11.251'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Evaluation of cost effective diagnostic tools in characterisation of Acute Leukemia in Southern India. | The incidence of Acute Leukemia (AL) subtypes varies according to geographical distribution and more predominant in developing countries. The aim here was to evaluate the usefulness of cost effective diagnostic tools in characterization of Acute Lymphoblastic Leukemia (ALL) in resource poor population. One hundred and ... | ['Adolescent', 'Child', 'Child, Preschool', 'Cytological Techniques', 'Developing Countries', 'Female', 'Histocytochemistry', 'Humans', 'Immunophenotyping', 'India', 'Leukemia, Myeloid, Acute', 'Male', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'Receptors, Immunologic'] | 27,080,214 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.225.500', 'E05.200.500', 'E05.242'], ['I01.615.500.300'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 |
Characteristics of 1573 healthcare workers who underwent nasopharyngeal swab testing for SARS-CoV-2 in Milan, Lombardy, Italy. | OBJECTIVES: The management of healthcare workers (HCWs) exposed to confirmed cases of coronavirus disease 2019 (COVID-19) is still a matter of debate. We aimed to assess in this group the attack rate of asymptomatic carriers and the symptoms most frequently associated with infection.METHODS: Occupational and clinical c... | ['Adult', 'Asymptomatic Diseases', 'Betacoronavirus', 'COVID-19', 'COVID-19 Testing', 'Clinical Laboratory Techniques', 'Convalescence', 'Coronavirus Infections', 'Female', 'Fever', 'Health Personnel', 'Hospitals, University', 'Humans', 'Infectious Disease Transmission, Patient-to-Professional', 'Italy', 'Male', 'Middl... | 32,569,835 | [['M01.060.116'], ['C23.550.291.187'], ['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['E01.370.225.312', 'E05.200.312'], ['E01.370.225', 'E05.200'], ['C23.550.291.562'], ['C01.925.78... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A novel phosphoprotein is induced during bone marrow commitment to dendritic cells. | Dendritic cells (DCs) play an important role in vertebrate immunity, but little is known of the molecular events associated with their development from bone marrow (BM). This report describes induction of a signature protein marking BM commitment to DCs. Using a standard procedure, DCs were generated from BM by cultiva... | ['Amino Acid Sequence', 'Animals', 'Antigens, Surface', 'Bone Marrow Cells', 'Cell Differentiation', 'Cells, Cultured', 'Dendritic Cells', 'Immunophenotyping', 'Mice', 'Mice, Inbred BALB C', 'Molecular Sequence Data', 'Molecular Weight', 'Phosphoproteins', 'Rabbits', 'Stem Cells'] | 15,358,210 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D23.050.301'], ['A11.148', 'A15.378.316'], ['G04.152'], ['A11.251'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['E01.370.225.812.447', 'E05.200.812.447', 'E05.478.594.450'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Improved catalytic and stereoselective glycosylation with glycosyl N-trichloroacetylcarbamate: application to various 1-hydroxy sugars. | Efficient catalytic and stereoselective glycosylation was achieved by activating a glycosyl N-trichloroacetylcarbamate with a catalytic amount of Lewis acid in the presence of a glycosyl acceptor and 5A molecular sieves. Catalytic one-pot dehydrative glycosylation of a 1-hydroxy carbohydrate was achieved stereoselectiv... | ['Carbamates', 'Carbohydrates', 'Catalysis', 'Glycosylation', 'Magnetic Resonance Spectroscopy', 'Models, Chemical', 'Molecular Structure', 'Stereoisomerism'] | 20,207,348 | [['D02.241.081.251'], ['D09'], ['G02.130'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['E05.196.867.519'], ['E05.599.495'], ['G02.111.570', 'G02.466'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cardiac Troponin T Release after Football 7 in Healthy Children and Adults. | The objective of this study was to compare the release of cardiac troponin T (cTnT) after a football 7 match between two cohorts of children and adult players. Thirty-six male football players (children = 24, adult = 12) played a football 7 match, and cTnT was measured before, and 3 h after exercise. Concentrations of ... | ['Adult', 'Athletes', 'Biomarkers', 'Child', 'Humans', 'Male', 'Middle Aged', 'Myocardium', 'Soccer', 'Troponin T'] | 32,033,112 | [['M01.060.116'], ['M01.072'], ['D23.101'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['I03.450.642.845.800'], ['D05.500.945.962', 'D05.750.078.730.825.962', 'D12.776.210.500.910.962', 'D12.776.220.525.825.962']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
The functional interactions between CD98, beta1-integrins, and CD147 in the induction of U937 homotypic aggregation. | CD98 is expressed on both hematopoietic and nonhematopoietic cells and has been implicated in a variety of different aspects of cell physiology and immunobiology. In this study, the functional interactions between CD98 and other adhesion molecules on the surface of the promonocyte line U937 are examined by means of a q... | ['Antibodies', 'Antigens, CD', 'Antigens, Neoplasm', 'Antigens, Surface', 'Avian Proteins', 'Basigin', 'Blood Proteins', 'Carrier Proteins', 'Cell Adhesion', 'Cell Death', 'Deoxyglucose', 'Edetic Acid', 'Flow Cytometry', 'Fluorescein-5-isothiocyanate', 'Fluorescent Dyes', 'Fusion Regulatory Protein-1', 'Humans', 'Integ... | 11,435,306 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.285'], ['D23.050.301'], ['D12.776.095'], ['D12.776.395.550.045', 'D12.776.543.550.187', 'D23.050.285.040'], ['D12.776.124'], ['D12.776.157'], ['G04.022'], ['G04.146'], ['D09.254.229'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
DNA separation by capillary electrophoresis with hydrophilic substituted celluloses as coating and sieving polymers. Application to the analysis of genetically modified meals. | A coating procedure based on the physical adsorption of hydroxypropyl cellulose onto the wall of a capillary column has been successfully used for the separation of DNA fragments up to 500 bp. The method uses a running Tris-phosphate-EDTA buffer containing 2-hydroxyethyl cellulose as sieving polymer. The separation pro... | ['Adsorption', 'Buffers', 'Cellulose', 'DNA, Plant', 'Electrophoresis, Capillary', 'Food Analysis', 'Food, Genetically Modified', 'Plants, Genetically Modified', 'Soybeans', 'Zea mays'] | 15,638,166 | [['G01.030', 'G02.020'], ['D27.720.470.280'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['D13.444.308.435'], ['E05.196.401.190', 'E05.301.300.190'], ['E05.362', 'J01.576.423.850.100'], ['G07.203.300.518', 'J02.500.518'], ['B01.650.520', 'B05.620.600'], ['B01.650.940.800.5... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Francisella Tularensis Clades B.FTN002-00 and B.13 Are Associated With Distinct Pathology in the European Brown Hare (Lepus europaeus). | Tularemia is a severe disease caused by Francisella tularensis This bacterium has a major pathogenic potential in countless animal species as well as in humans. Despite the relatively significant body of literature available on this microorganism, many questions are still open concerning its biological cycle in the env... | ['Animals', 'Animals, Wild', 'Female', 'Francisella tularensis', 'Hares', 'Male', 'Polymerase Chain Reaction', 'Tularemia'] | 26,933,097 | [['B01.050'], ['B01.050.050.300'], ['B03.440.400.425.340.590', 'B03.660.250.200.750'], ['B01.050.150.900.649.313.968.400'], ['E05.393.620.500'], ['C01.150.252.400.900', 'C01.920.930.943']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cometabolic biodegradation of 4-chlorophenol by sequencing batch reactors at different temperatures. | The simultaneous removal of 4-chlorophenol (4-CP) and phenol in lab-scale sequencing batch reactors at different temperatures has been studied. Phenol feed concentration was fixed at 525 mg/L and 4-CP concentration was increased from 105 to 2100 mg/L at a constant hydraulic residence time (HRT) of 10.5 d. Complete phen... | ['Acclimatization', 'Anaerobiosis', 'Biodegradation, Environmental', 'Biomass', 'Bioreactors', 'Chlorophenols', 'Ecotoxicology', 'Kinetics', 'Oxygen', 'Oxygen Consumption', 'Phenols', 'Temperature', 'Time Factors'] | 19,450,978 | [['G07.025.133', 'G16.012.500.133'], ['G02.111.062', 'G03.078'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['G16.500.275.157.100', 'N06.230.124.100'], ['E07.115', 'J01.897.120.115'], ['D02.455.426.559.389.261.190', 'D02.455.426.559.389.657.190'], ['H01.158.273.248.500', 'H01.158.891.211', 'H01.277.249.500', 'H02.... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Observing washing and dressing of stroke patients: nursing intervention compared with occupational therapists. What is the difference? | This study sought to compare the interventions of qualified nurses with those of occupational therapists during morning care with the same population of stroke patients. Nonparticipant structured observation was used to identify the activities and interventions carried out by each of the two groups in a naturalistic ca... | ['Activities of Daily Living', 'Baths', 'Education, Nursing', 'England', 'Humans', 'Occupational Therapy', 'Professional-Patient Relations', 'Statistics, Nonparametric', 'Stroke', 'Stroke Rehabilitation'] | 11,155,113 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['E02.056.110'], ['I02.358.462'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.169.063.500.489', 'E02.831.489', 'H02.010.500'], ['F01.829.401.650', 'N05.300.660'], ['E05.318.740.995', 'N05.715.360.750.760', 'N0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Deleterious effects of purulent sputum sol on human ciliary function in vitro: at least two factors identified. | Patients with chronic bronchial sepsis have impaired mucociliary clearance. A study was carried out on the effect of sputum sol (obtained by rapid centrifugation of purulent sputum) from 20 patients with chronic bronchial sepsis on the beating of human nasal cilia in vitro by a photometric technique. Thirteen sols caus... | ['Bronchiectasis', 'Chloroform', 'Cilia', 'Cystic Fibrosis', 'Endopeptidases', 'Humans', 'In Vitro Techniques', 'Nasal Mucosa', 'Protease Inhibitors', 'Serine Endopeptidases', 'Sputum'] | 3,303,429 | [['C08.127.384'], ['D02.455.526.439.224', 'D02.455.526.913.810'], ['A11.284.180.165'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['D08.811.277.656.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['A04.531.520', 'A04.760.600', 'A10.615.550.760.600'], ['D27.505.519.389.745'], ['D0... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Study of the effects of education on the management of urine drainage systems by patients and carers. | A randomized controlled trial was undertaken to test the effects of an education programme, which included an information booklet and demonstration, on the management of urine drainage systems by patients and carers. A total of 45 patients, new and established users, were included. Data were collected at pretest, test ... | ['Aged', 'Bacteriuria', 'Female', 'Hand Disinfection', 'Humans', 'Male', 'Middle Aged', 'Pamphlets', 'Patient Education as Topic', 'Program Evaluation', 'Randomized Controlled Trials as Topic', 'Self Care', 'Urinary Catheterization'] | 2,193,045 | [['M01.060.116.100'], ['C01.915.219', 'C12.777.892.219', 'C13.351.968.892.219'], ['N06.850.670.150.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['L01.178.682.707'], ['I02.233.332.500', 'N02.421.726.407.680'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['E05.318.372.250.250.365.50... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Stapling techniques to facilitate resection of the head of the pancreas. | Thirteen patients underwent duodenocephalopancreatectomy (DCP) with the mechanical staplers to divide the pancreatic neck and to secure haemostasis of the retroportal pancreatic lamina. The stapling techniques used on the pancreas are described. In nine patients with DCP the stapled distal pancreas was anastomosed to t... | ['Adult', 'Aged', 'Anastomosis, Roux-en-Y', 'Choledochostomy', 'Female', 'Humans', 'Jejunostomy', 'Male', 'Middle Aged', 'Pancreas', 'Pancreaticojejunostomy', 'Surgical Staplers'] | 1,941,738 | [['M01.060.116'], ['M01.060.116.100'], ['E04.035.070', 'E04.210.070'], ['E04.035.200', 'E04.210.120.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.210.338.523', 'E04.579.338.523'], ['M01.060.116.630'], ['A03.734'], ['E04.035.703', 'E04.210.762'], ['E07.858.700.750']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Predictions through evidence accumulation over time. | It has been proposed that the brain specializes in predicting future states of the environment. These predictions are probabilistic, and must be continuously updated on the basis of their mismatch with actual evidence. Although electrophysiological data disclose neural activity patterns in relation to predictive proces... | ['Adult', 'Anticipation, Psychological', 'Brain', 'Electroencephalography', 'Evoked Potentials', 'Female', 'Humans', 'Male', 'Photic Stimulation', 'Probability', 'Young Adult'] | 29,323,172 | [['M01.060.116'], ['F02.463.093'], ['A08.186.211'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.723.729'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Theophylline serum levels unmodified by postprandial administration of a sustained-release preparation (Teonova). | The authors studied serum theophylline levels after administration of new single-dose capsules: Teonova. Special attention was paid to possible fluctuations of serum theophylline after administration of the drug following a standardized meal. For this purpose a test was carried out on eight male patients with intrinsic... | ['Aged', 'Asthma', 'Delayed-Action Preparations', 'Humans', 'Male', 'Middle Aged', 'Theophylline'] | 3,366,501 | [['M01.060.116.100'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D26.255.210', 'E02.319.300.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D03.132.960.751', 'D03.633.100.759.758.824.751']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Moral enhancement, gnosticism, and some philosophical paradoxes. | This article examines the concept of moral enhancement from two different perspectives. The first is a bottom-up approach, which aims at identifying fundamental moral traits and subcapacities as targets for enhancement. The second perspective, a top-down approach, is holistic and in line with virtue ethics. Both perspe... | ['Biological Evolution', 'Cognition', 'Humans', 'Moral Development', 'Morals', 'Religion', 'Social Values', 'Spirituality', 'Virtues'] | 25,473,860 | [['G05.045', 'G16.075'], ['F02.463.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.747.616', 'F01.829.500.679', 'K01.752.566.739'], ['F01.829.500', 'K01.752.566'], ['K01.844'], ['F01.829.873'], ['F02.880.705', 'K01.844.664.500'], ['F01.829.500.840', 'K01.752.566.934']] | ['Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Absorption of lithium following administration of slow-release and conventional preparations. | The plasma lithium levels of 18 subjects receiving one standard and two slow-release preparations of lithium carbonate were measured at frequent intervals during the 24 hours following oral ingestion of a single dose of the drug. Although the slow-release tablets showed slow-release in vitro, this was not so in vivo. O... | ['Absorption', 'Administration, Oral', 'Adult', 'Aged', 'Biological Availability', 'Delayed-Action Preparations', 'Drug Evaluation', 'Feces', 'Female', 'Humans', 'Lithium', 'Male', 'Middle Aged', 'Time Factors'] | 935,297 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['G03.787.151', 'G07.690.725.129'], ['D26.255.210', 'E02.319.300.253'], ['E05.290.625', 'E05.337.425'], ['A12.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.549.450', 'D01.... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Long-term survival in a patient with low-level inflammatory markers and liver metastasis, converted resectable by TACE. | Case report presents the successful treatment of unresectable liver metastasis in a patient with colon cancer. A 44-year-old male underwent right hemicolectomy followed by capecitabine for a moderately differentiated adenocarcinoma of the colon. 2 years later, a liver metastatic lesion was detected and had increased in... | ['Adenocarcinoma', 'Adult', 'Biomarkers', 'Camptothecin', 'Capecitabine', 'Chemoembolization, Therapeutic', 'Colectomy', 'Colonic Neoplasms', 'Fluorouracil', 'Hepatectomy', 'Humans', 'Inflammation Mediators', 'Irinotecan', 'Leucovorin', 'Liver Neoplasms', 'Male', 'Microspheres', 'Organoplatinum Compounds', 'Oxaliplatin... | 29,032,738 | [['C04.557.470.200.025'], ['M01.060.116'], ['D23.101'], ['D03.132.151'], ['D03.383.742.680.245.500.425', 'D03.383.742.698.875.404.425', 'D13.570.230.329.313', 'D13.570.685.245.500.425'], ['E02.520.360.150', 'E02.926.500.150'], ['E04.210.219'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effects of ionophores on steroidogenesis and morphology of avian granulosa cells. | Granulosa cells, isolated by collagenase digestion from the mature ovarian follicle of laying hens, were incubated in the presence of two ionophores, lasalocid (X537A) and ionomycin, to determine their effects on basal and stimulated steroidogenesis, as well as their effects on various cell parameters including DNA, RN... | ['Animals', 'Chickens', 'Ethers', 'Female', 'Granulosa Cells', 'Hydroxycholesterols', 'In Vitro Techniques', 'Ionomycin', 'Kinetics', 'Lasalocid', 'Microscopy, Electron', 'Mitochondria', 'Progesterone'] | 3,607,849 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D02.355'], ['A05.360.319.114.630.535.200', 'A06.300.312.497.535.300', 'A11.382.812', 'A11.436.329'], ['D04.210.500.247.222.284.800.500', 'D04.210.500.247.808.197.800.500', 'D10.570.938.208.825.500'], ['E05.481'], ['D10.251.355.391'], ['G01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Monitoring phase behavior of sub- and supercritical CO2 confined in porous fractal silica with 85% porosity. | Phase behavior of CO(2) confined in porous fractal silica with volume fraction of SiO(2) phi(s) = 0.15 was investigated using small-angle neutron scattering (SANS) and ultrasmall-angle neutron scattering (USANS) techniques. The range of fluid densities (0 < (rho(CO(2)))(bulk) < 0.977 g/cm(3)) and temperatures (T = 22 d... | ['Carbon Dioxide', 'Fractals', 'Neutron Diffraction', 'Porosity', 'Pressure', 'Scattering, Small Angle', 'Silicon Dioxide', 'Temperature'] | 20,043,698 | [['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['E05.599.125', 'G17.290'], ['E05.196.309.555', 'E05.196.822.650', 'G01.867.650', 'G02.551'], ['G01.374.710'], ['G01.374.715'], ['E05.196.822.830', 'G01.867.755'], ['D01.578.750', 'D01.650.550.825', 'D01.837.725'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.7... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Radical excision and reconstruction of chronic tibial osteomyelitis with microvascular muscle flaps. | We report a series of 21 patients with chronic osteomyelitis of the tibia treated with microvascular muscle flap reconstruction. All patients underwent a radical bone and soft-tissue excision until healthy, well-bleeding tissue was exposed. Six patients required cancellous bone grafting. Latissimus dorsi was used in 14... | ['Adult', 'Aged', 'Bone Transplantation', 'Chronic Disease', 'Female', 'Humans', 'Male', 'Microcirculation', 'Middle Aged', 'Orthopedic Procedures', 'Osteomyelitis', 'Surgical Flaps', 'Tibia', 'Treatment Outcome'] | 11,871,378 | [['M01.060.116'], ['M01.060.116.100'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.330.100.645'], ['M01.060.116.630'], ['E02.718', 'E04.555'], ['C01.160.495', 'C05.116.165.495'], ['A10.850.710', 'E07.862.710'], ['A02.835.232.043.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Prescribing valproate to girls and women of childbearing age in Germany : Analysis of trends based on claims data]. | BACKGROUND: Measures to raise awareness of the teratogenic potential of valproate and restrict its use in girls/women of childbearing age have been intensified. For Germany, the impact of these measures on valproate prescription rates remains unknown.OBJECTIVES: Trends in prescribing valproate, the underlying treatment... | ['Adult', 'Anticonvulsants', 'Antimanic Agents', 'Bipolar Disorder', 'Drug Prescriptions', 'Drug Utilization', 'Epilepsy', 'Female', 'Germany', 'Humans', 'Migraine Disorders', "Practice Patterns, Physicians'", 'Valproic Acid'] | 29,922,910 | [['M01.060.116'], ['D27.505.954.427.080'], ['D27.505.696.277.950.025', 'D27.505.954.427.210.950.025', 'D27.505.954.427.700.872.025'], ['F03.084.500'], ['E02.319.307', 'N02.421.668.778.500'], ['N04.452.706.477'], ['C10.228.140.490'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.546.399... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Pulmonary hypertension and pregnancy]. | Pregnancy in the context of pulmonary hypertension is characterised by high mortality for the mother and the foetus and is therefore strongly discouraged ; contraception has to be prescribed to patients in reproductive age. Women who decide to continue their pregnancy should be followed by multidisciplinary teams in sp... | ['Contraception', 'Female', 'Humans', 'Hypertension, Pulmonary', 'Pregnancy', 'Pregnancy Complications, Cardiovascular'] | 29,143,500 | [['E02.875.194'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['G08.686.784.769'], ['C13.703.634', 'C14.583']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The influence of enalapril or spironolactone on experimental cyclosporin nephrotoxicity. | Adult Sprague-Dawley rats treated daily for 14 days with 50 mg/kg cyclosporin A (CsA) exhibited nephrotoxicity, characterized by reduced glomerular filtration rate, decreased urinary sodium and potassium flow, tubular enzymuria and proximal tubular structural damage. Elevations in plasma renin activity (PRA) were obser... | ['Acetylglucosaminidase', 'Animals', 'Cyclosporins', 'Enalapril', 'Glomerular Filtration Rate', 'Kidney', 'Male', 'Potassium', 'Rats', 'Rats, Inbred Strains', 'Renin', 'Sodium', 'Spironolactone'] | 3,030,332 | [['D08.811.277.450.483.180.500'], ['B01.050'], ['D04.345.566.235', 'D12.644.641.235'], ['D12.644.456.345.360'], ['E01.370.390.400.300', 'G08.852.357'], ['A05.810.453'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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