Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Activity of two different silencer elements of the chicken lysozyme gene can be compensated by enhancer elements. | The chicken lysozyme gene is constitutively expressed in macrophages. Transfection of recombinant genes containing different portions of the lysozyme 5' upstream region revealed the existence of two negative transcriptional elements within 1 kb upstream of the start sites. Both elements placed upstream or downstream of... | ['Animals', 'Base Sequence', 'Chickens', 'Chromosome Deletion', 'Enhancer Elements, Genetic', 'Genes', 'Genes, Regulator', 'Macrophages', 'Muramidase', 'Mutation', 'Plasmids'] | 3,665,875 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['G02.111.570.080.689.330', 'G0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Rupture and Release: A Role for Soluble Erythrocyte Content in the Pathology of Cerebral Malaria. | Cerebral malaria (CM) is the most severe form of malaria and causes high associated mortality. We propose a multistep process for CM pathology that is initiated by cytoadhesion of infected erythrocytes to the brain vasculature, followed by rupture and release of contents that complete the disruption of the blood-brain ... | ['Blood-Brain Barrier', 'Cell Adhesion', 'Endothelium, Vascular', 'Erythrocytes', 'Humans', 'Malaria, Cerebral', 'Malaria, Falciparum', 'Protein Binding'] | 28,709,836 | [['A07.035', 'A08.186.211.035'], ['G04.022'], ['A07.015.700.500', 'A10.272.491.355'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.207.205.300.500', 'C01.610.105.300.500', 'C01.610.752.530.620', 'C01.920.875.620', 'C10.228.228.205.300.500'], ['C01.610.752.530... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transition protein 1 from boar late spermatid nuclei having DNA-melting activity is a dimeric protein. | Polyacrylamide gel electrophoretic behavior of boar transition protein 1, TP1, under dissociating and non-dissociating buffer conditions, and titration of fluorescently labeled TP1 with increasing amounts of TP1 showed that TP1 formed a dimer without intermolecular disulfide bond. TP1 dimer with intermolecular disulfid... | ['Animals', 'Chromosomal Proteins, Non-Histone', 'DNA', 'DNA, Single-Stranded', 'Dimerization', 'Electrophoresis, Polyacrylamide Gel', 'Fluoresceins', 'Fluorescent Dyes', 'Male', 'Maleimides', 'Nucleic Acid Denaturation', 'Protein Denaturation', 'Rats', 'Spermatids', 'Swine'] | 9,530,514 | [['B01.050'], ['D12.776.660.235', 'D12.776.664.235'], ['D13.444.308'], ['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['G02.206', 'G03.230'], ['E05.196.401.402', 'E05.301.300.319'], ['D02.455.426.779.347', 'D03.633.300.953.275', 'D04.711.347'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D02.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pancreatoduodenectomy with portal vein resection for distal cholangiocarcinoma. | BACKGROUND: Little is known about the value of portal vein (PV) resection in distal cholangiocarcinoma. The aim of this study was to evaluate the clinical significance of PV resection in distal cholangiocarcinoma.METHODS: Patients who underwent pancreatoduodenectomy (PD) for distal cholangiocarcinoma between 2001 and 2... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Bile Duct Neoplasms', 'Blood Loss, Surgical', 'Blood Transfusion', 'Cholangiocarcinoma', 'Female', 'Follow-Up Studies', 'Humans', 'Japan', 'Lymphatic Metastasis', 'Male', 'Margins of Excision', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Invasiveness', 'Opera... | 28,782,798 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.274.120.250', 'C06.130.120.120', 'C06.130.320.120', 'C06.301.120.250'], ['C23.550.414.300', 'C23.550.505.300'], ['E02.095.135'], ['C04.557.470.200.025.450'], ['E05.318.372.500.750.249', 'N05.715.360.330.500... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Biomechanical properties of suture anchor repair compared with transosseous sutures in patellar tendon ruptures: a cadaveric study. | BACKGROUND: Ruptures of the patellar tendon are debilitating injuries requiring surgical repair. Reliable data about the most appropriate suture technique and suture material are missing. The standard procedure consists of refixing the tendon with sutures in transpatellar tunnels, sometimes combined with augmentation.H... | ['Aged', 'Biomechanical Phenomena', 'Female', 'Humans', 'Knee Injuries', 'Male', 'Middle Aged', 'Patellar Ligament', 'Suture Techniques'] | 23,982,397 | [['M01.060.116.100'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558.554'], ['M01.060.116.630'], ['A02.513.514.475', 'A02.835.583.512.475', 'A02.880.438', 'A10.165.669.514.475'], ['E04.987.775']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Colour vision variation in leaf-nosed bats (Phyllostomidae): Links to cave roosting and dietary specialization. | Bats are a diverse radiation of mammals of enduring interest for understanding the evolution of sensory specialization. Colour vision variation among species has previously been linked to roosting preferences and echolocation form in the suborder Yinpterochiroptera, yet questions remain about the roles of diet and habi... | ['Animals', 'Brazil', 'Caves', 'Chiroptera', 'Color Vision', 'Diet', 'Evolution, Molecular', 'Opsins', 'Phylogeny'] | 30,059,176 | [['B01.050'], ['Z01.107.757.176'], ['G01.311.169', 'G16.500.275.067', 'N06.230.066'], ['B01.050.150.900.649.313.937'], ['F02.830.816.964.124', 'G11.561.790.964.124', 'G14.935.124'], ['G07.203.650.240'], ['G05.045.250', 'G16.075.250'], ['D12.776.306.466', 'D23.767.930.750'], ['G05.697', 'G16.075.605', 'L01.100.697']] | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Surgical treatment of patients with single and dual pathology: relevance of lesion and of hippocampal atrophy to seizure outcome. | Modern neuroimaging can disclose epileptogenic lesions in many patients with partial epilepsy and, at times, display the coexistence of hippocampal atrophy in addition to an extrahippocampal lesion (dual pathology). We studied the postoperative seizure outcome of 64 patients with lesional epilepsy (median follow-up, 30... | ['Adolescent', 'Adult', 'Aged', 'Atrophy', 'Child', 'Epilepsies, Partial', 'Female', 'Hippocampus', 'Humans', 'Male', 'Middle Aged', 'Treatment Outcome'] | 9,040,735 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C23.300.070'], ['M01.060.406'], ['C10.228.140.490.360'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cerebellar haemorrhage in a 12-year-old girl with giant dural sinus malformation. | Dural sinus malformation (DSM), a form of dural arteriovenous shunt (DAVS), is an extremely rare vascular anomaly seen less frequently than vein of Galen malformation. We report a case of DSM, detailing initial presentation and delayed complication of cerebellar haemorrhage due to venous stasis within the DSM leading t... | ['Central Nervous System Vascular Malformations', 'Cerebral Angiography', 'Cerebral Hemorrhage', 'Child', 'Collateral Circulation', 'Cranial Sinuses', 'Dura Mater', 'Female', 'Humans', 'Magnetic Resonance Angiography', 'Tomography, X-Ray Computed'] | 22,329,414 | [['C10.500.190', 'C14.240.850.875', 'C16.131.240.850.875', 'C16.131.666.190'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['M01.060.406'... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
1Alpha-hydroxyvitamin D3 prevents the decrease of bone mineral density in lactating beagles. | We assessed the change of bone mineral density (BMD) in lactating beagles with dual energy X-ray absorptiometry (DXA) and the preventive effect of 1alpha-hydroxyvitamin D3 (1alpha(OH)D3) on the BMD. Beagles, two to five years old, were used for detecting the time course change of BMD. Since the coefficient of variation... | ['Absorptiometry, Photon', 'Acid Phosphatase', 'Alkaline Phosphatase', 'Animals', 'Bone Density', 'Bone Resorption', 'Calcium', 'Creatinine', 'Dogs', 'Female', 'Hydroxycholecalciferols', 'Isoenzymes', 'Lactation', 'Lumbar Vertebrae', 'Pregnancy', 'Tartrate-Resistant Acid Phosphatase', 'Tibia'] | 10,676,894 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['D08.811.277.352.650.025'], ['D08.811.277.352.650.035'], ['B01.050'], ['G11.427.100'], ['C05.116.264', 'G11.427.213.150'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D03.383.129.308.207'], ['B01.050.150.900.649.313.750.250.216.200'], ['D04.210.500.247.222.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antiproliferative small-molecule inhibitors of transcription factor LSF reveal oncogene addiction to LSF in hepatocellular carcinoma. | Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Despite the prevalence of HCC, there is no effective, systemic treatment. The transcription factor LSF is a promising protein target for chemotherapy; it is highly expressed in HCC patient samples and cell lines, and promotes oncogenesis in roden... | ['Animals', 'Benzodioxoles', 'Carcinoma, Hepatocellular', 'Cell Proliferation', 'Cell Survival', 'DNA-Binding Proteins', 'Drug Screening Assays, Antitumor', 'Gene Expression Regulation, Neoplastic', 'Genes, Reporter', 'Hepatocytes', 'Humans', 'Inhibitory Concentration 50', 'Liver Neoplasms', 'Mice', 'Models, Chemical',... | 22,396,589 | [['B01.050'], ['D03.383.246.118', 'D03.633.100.115'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['D12.776.260'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['G05.308.370'], ['G05.360.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Historical presence of invasive fish in the biosphere reserve sierra de Huautla, Mexico]. | The effects of invasive species on native ecosystems are varied, and these have been linked to the disappearance or decline of native fauna, changes in community structure, modification of ecosystems and as vectors of new diseases and parasites. Besides, the development of trade in species for ornamental use has contri... | ['Animals', 'Biodiversity', 'Ecosystem', 'Fishes', 'Introduced Species', 'Mexico', 'Population Density', 'Population Dynamics', 'Principal Component Analysis', 'Seasons'] | 23,894,937 | [['B01.050'], ['G16.500.275.157.049', 'N06.230.124.049'], ['G16.500.275.157', 'N06.230.124'], ['B01.050.150.900.493'], ['B01.050.050.580', 'G16.500.275.157.049.400', 'N06.230.124.049.400'], ['Z01.107.567.589'], ['N01.224.600', 'N06.850.505.400.600'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['E05.318.740.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
The role of perceived benefits and barriers in colorectal cancer screening in intervention trials among African Americans. | The Health Belief Model (HBM) is widely used in health behavior interventions. The lack of diverse samples in the development of this theory warrants additional study on how it performs among minorities. While studies have utilized HBM to address colorectal cancer (CRC) screening, limited information exists confirming ... | ['African Americans', 'Aged', 'Colonoscopy', 'Colorectal Neoplasms', 'Early Detection of Cancer', 'Faith-Based Organizations', 'Female', 'Health Education', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', 'Occult Blood', 'United States'] | 29,757,376 | [['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Optimization of a comprehensive two-dimensional normal-phase and reversed-phase liquid chromatography system. | The present investigation is based on the evaluation of the performance of a comprehensive two-dimensional liquid chromatography (LCxLC) system during method optimization. The LCxLC set-up, operated in normal phase (NP) mode (adsorption) in the first dimension (1D) and reversed-phase (RP) mode in the second dimension (... | ['Chromatography, Liquid', 'Hydrocarbons'] | 17,059,684 | [['E05.196.181.400'], ['D02.455']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Carcinoma of the splenic flexure]. | The Authors report their experience in the management of 25 cancers of the splenic flexure corresponding to 4.8% of large bowel cancers overall observed. Twelve patients underwent elective surgery consisting in a left hemicolectomy, which in 1 of the 12 cases required an associated distal splenopancreatectomy. Operativ... | ['Aged', 'Anastomosis, Surgical', 'Colectomy', 'Colon, Sigmoid', 'Colostomy', 'Female', 'Humans', 'Ileum', 'Male', 'Middle Aged', 'Pancreatectomy', 'Postoperative Complications', 'Rectum', 'Splenic Neoplasms'] | 1,419,518 | [['M01.060.116.100'], ['E04.035'], ['E04.210.219'], ['A03.556.124.526.356.668', 'A03.556.249.249.356.668'], ['E04.210.338.225', 'E04.579.338.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684.249', 'A03.556.249.124'], ['M01.060.116.630'], ['E04.210.752'], ['C23.550.767'], ['A03.556.124.526.767', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A new look at pericardial substitutes. | The presence of pericardial adhesions may increase morbidity and mortality during reoperation for cardiac disease. Pericardial substitutes (patches) are commercially available, and reportedly they reduce or prevent adhesions. We implanted five (1984 to 1985) newer pericardial substitutes in dogs. A new polytetrafluoroe... | ['Animals', 'Bioprosthesis', 'Cardiomyopathies', 'Cicatrix', 'Dogs', 'Pericardium', 'Polytetrafluoroethylene', 'Tissue Adhesions'] | 3,613,629 | [['B01.050'], ['E07.695.100'], ['C14.280.238'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['B01.050.150.900.649.313.750.250.216.200'], ['A07.541.795', 'A10.615.789.470'], ['D05.750.395.616', 'D25.720.395.616', 'J01.637.051.720.395.616'], ['C23.550.355.274.840']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The orbicularis oculi reflex: pathologic studies in childhood. | The orbicularis oculi reflex was studied in 12 children with intrinsic brain stem gliomas and in six children with other posterior fossa pathology. The results were compared with previously established childhood normal values. Seventy-eight percent of the children demonstrated a pathologic alteration of the reflex comp... | ['Adolescent', 'Brain Diseases', 'Brain Neoplasms', 'Brain Stem', 'Child', 'Child, Preschool', 'Eyelids', 'Glioma', 'Humans', 'Reflex'] | 561,347 | [['M01.060.057'], ['C10.228.140'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['A08.186.211.132'], ['M01.060.406'], ['M01.060.406.448'], ['A01.456.505.420.504', 'A09.371.337'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Emotional regulation processes: influence on pain and disability in fibromyalgia patients. | OBJECTIVES: Fibromyalgia (FM) is a chronic syndrome characterised by widespread musculoskeletal pain associated with other symptoms, including psychological distress. While negative mood (anxiety, depression, and anger) has been widely explored in FM, few studies have investigated emotional dysregulation. Our purpose w... | ['Anger', 'Anxiety', 'Depression', 'Disability Evaluation', 'Emotional Regulation', 'Fibromyalgia', 'Humans', 'Pain'] | 31,928,594 | [['F01.470.093'], ['F01.470.132'], ['F01.145.126.350'], ['E01.370.400'], ['F01.145.813.595.500', 'F01.470.311'], ['C05.651.324', 'C05.799.321', 'C10.668.491.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444']] | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interactions of methoxychlor, methoxychlor base-soluble contaminant, and 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane with rat uterine estrogen receptor. | Laboratory grade methoxychlor (99% pure), base-washed methoxychlor, and a metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane (HPTE), were tested for their ability to compete with [3 H] estradiol-17 beta ([3 H]E2) for specific binding to the estrogen receptor from immature rat uterine cytosol. Th... | ['Animals', 'Cytosol', 'DDT', 'Drug Contamination', 'Female', 'Hydrocarbons, Chlorinated', 'Kinetics', 'Methoxychlor', 'Rats', 'Receptors, Estrogen', 'Trichloroethanes', 'Uterus'] | 731,734 | [['B01.050'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D02.455.526.439.255'], ['N06.850.360'], ['D02.455.526.439'], ['G01.374.661', 'G02.111.490'], ['D02.455.526.439.610'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.826.750.350', 'D12.776.930.778.350'], ['D02.455.526.439.927'... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Different reactive oxygen species lead to distinct changes of cellular metal ions in the eukaryotic model organism Saccharomyces cerevisiae. | Elemental uptake and export of the cell are tightly regulated thereby maintaining the ionomic homeostasis. This equilibrium can be disrupted upon exposure to exogenous reactive oxygen species (ROS), leading to reduction or elevation of the intracellular metal ions. In this study, the ionomic composition in the eukaryot... | ['Aluminum', 'Benzene Derivatives', 'Copper', 'Cyclohexanones', 'Diamide', 'Hydrogen Peroxide', 'Ions', 'Linoleic Acids', 'Lipid Peroxides', 'Magnesium', 'Manganese', 'Models, Molecular', 'Oxidants', 'Oxidative Stress', 'Peroxynitrous Acid', 'Potassium', 'Reactive Oxygen Species', 'Saccharomyces cerevisiae', 'Vitamin K... | 22,174,654 | [['D01.268.557.050', 'D01.552.547.050'], ['D02.455.426.559.389'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D02.455.426.392.368.367.340', 'D02.522.400'], ['D02.172.300'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D01.248.497'], ['D10.251.355.3... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Why is the lower torso protected in traumatic asphyxia? A new hypothesis. | Traumatic asphyxia secondary to a crush injury of the chest is characterized by craniocervical cyanosis, subconjunctival hemorrhage, and severe vascular engorgement of the head and neck. These signs are believed to be due to high venous pressures causing stasis and capillary rupture. A "fear response" that produces a s... | ['Abdomen', 'Asphyxia', 'Humans', 'Male', 'Pressure', 'Respiration', 'Thoracic Injuries', 'Ultrasonography', 'Valsalva Maneuver', 'Vena Cava, Inferior'] | 2,645,838 | [['A01.923.047'], ['C23.550.260.095', 'C26.103'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.715'], ['G09.772.705'], ['C26.891'], ['E01.370.350.850'], ['E01.370.370.380.950', 'E01.370.386.700.950', 'G09.330.380.875', 'G09.772.910'], ['A07.015.908.949.648']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of HSP90 inhibitors as a novel class of senolytics. | Aging is the main risk factor for many chronic degenerative diseases and cancer. Increased senescent cell burden in various tissues is a major contributor to aging and age-related diseases. Recently, a new class of drugs termed senolytics were demonstrated to extending healthspan, reducing frailty and improving stem ce... | ['Aging', 'Animals', 'Apoptosis', 'Autophagy', 'Benzoquinones', 'Biological Assay', 'Biomarkers', 'Cellular Senescence', 'DNA-Binding Proteins', 'Down-Regulation', 'Drug Evaluation, Preclinical', 'Endonucleases', 'Female', 'Fibroblasts', 'HSP90 Heat-Shock Proteins', 'Human Umbilical Vein Endothelial Cells', 'Humans', '... | 28,871,086 | [['G07.345.124'], ['B01.050'], ['G04.146.954.035'], ['G04.011'], ['D02.806.250'], ['E05.091'], ['D23.101'], ['G04.043'], ['D12.776.260'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['E05.290.750', 'E05.337.550'], ['D08.811.277.352.355'], ['A11.329.228'], ['D12.776.580.216.380'], ['A11.436.275.682'], ['B01.050.1... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lupus nephritis in children and adolescents: results of the Italian Collaborative Study. | BACKGROUND: Lupus nephritis (LN) strongly affects the outcome in children with systemic lupus erythematosus (SLE). Many patients, however, have renal disease at onset, but lack a sufficient number of criteria to be diagnosed as SLE and develop delayed symptoms over time (d-SLE). Data on the clinical course, long-term o... | ['Adolescent', 'Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Humans', 'Immunosuppressive Agents', 'Infant', 'Kidney Failure, Chronic', 'Lupus Nephritis', 'Male', 'Prognosis', 'Retrospective Studies', 'Survival Rate'] | 23,345,627 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['M01.060.703'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['C12.777.419.570.363.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Unintentional strangulation by a cervical collar after attempted suicide by hanging. | We report the case of a young man who attempted suicide by hanging and whose neurological status deteriorated until the cervical collar, that had been correctly placed by the prehospital team, was removed. We discuss the physiopathological mechanisms leading to death in hanging that is, a blockage of the blood stream t... | ['Adult', 'Asphyxia', 'Device Removal', 'Emergency Medical Services', 'Follow-Up Studies', 'Glasgow Coma Scale', 'Humans', 'Immobilization', 'Intracranial Hypertension', 'Intracranial Pressure', 'Intubation, Intratracheal', 'Male', 'Neck Injuries', 'Orthotic Devices', 'Respiration, Artificial', 'Risk Assessment', 'Suic... | 21,183,526 | [['M01.060.116'], ['C23.550.260.095', 'C26.103'], ['E04.199'], ['N02.421.297'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.318.308.940.968.875.250', 'E05.944.500', 'N04.452.859.564.800.250', 'N05.715.360.300.715.500.800.325'], ['B01.050.150.900.649.313.988.400.112.4... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Maternal predictors of perinatal human immunodeficiency virus transmission. The New York City Perinatal HIV Transmission Collaborative Study Group. | This analysis sought to identify characteristics of pregnant human immunodeficiency virus type 1 (HIV-1)-infected women that predict mother-to-child HIV-1 transmission. Pregnant and immediately postpartum women at risk for HIV were enrolled at obstetric and pediatric care settings in New York City from 1986 to 1992. De... | ['AIDS Serodiagnosis', 'Adolescent', 'Adult', 'CD4-CD8 Ratio', 'Cohort Studies', 'Female', 'HIV Core Protein p24', 'HIV Infections', 'HIV-1', 'Humans', 'Immunoglobulins', 'Infant', 'Infant, Newborn', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Prospective Studies', 'Risk Factors', 'T-Lymphocyte Subsets'] | 8,078,735 | [['E01.370.225.812.735.060', 'E01.370.225.875.408.500', 'E05.200.812.735.060', 'E05.200.875.408.500', 'E05.478.594.760.060'], ['M01.060.057'], ['M01.060.116'], ['E01.370.225.500.195.107.595.500.150.160', 'E01.370.225.625.107.595.500.150.160', 'E05.200.500.195.107.595.500.150.160', 'E05.200.625.107.595.500.150.160', 'E0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of acute and chronic administration of two antibiotics, aztreonam and gentamicin, alone or in combination, on "open-field test" in mice. | A study aimed at investigating the behavioural effects of aztreonam and gentamicin, given separately or in combination, was carried out in mice. Animals were randomly assigned to two test conditions: acute and chronic treatment. Those receiving acute treatment had a single IP injection 60 min before the test. Those rec... | ['Animals', 'Aztreonam', 'Behavior, Animal', 'Female', 'Gentamicins', 'Injections, Intraperitoneal', 'Mice'] | 2,606,426 | [['B01.050'], ['D02.065.589.099.500.044', 'D02.886.108.500.044', 'D03.383.411.350.044', 'D03.633.100.300.500.044'], ['F01.145.113'], ['D09.408.051.374'], ['E02.319.267.530.490'], ['B01.050.150.900.649.313.992.635.505.500']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gustatory thalamus lesions in the rat: I. Innate taste preferences and aversions. | Two experiments examined the innate taste preferences and aversions of rats with electrolytic lesions of the gustatory thalamus (GT). Contrary to previous research, GT lesions had only a minor influence on intake of the 4 basic tastes as assessed with the 24-hr, 2-bottle preference test in Experiment 1. The same lesion... | ['Animals', 'Brain Mapping', 'Dietary Sucrose', 'Food Preferences', 'Instinct', 'Male', 'Neural Pathways', 'Rats', 'Rats, Sprague-Dawley', 'Taste', 'Taste Buds', 'Thalamic Nuclei'] | 8,864,265 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['D09.301.831.250', 'D09.698.629.305.770.200', 'D09.947.500.250', 'D09.947.750.770.200', 'D27.720.372.300.353.609.750.250', 'G07.203.300.362.831.250', 'G07.203.300.514.500.400.700.750.250', 'J02.500.362.831.250', 'J02.500.514.500.4... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Osteopontin and endostatin concentrations in peripheral blood of patients with adrenal tumors undergoing unilateral adrenalectomy. | Peripheral blood osteopontin (OPN) and endostatin (END) levels were studied in 35 patients with adrenal cortex tumors and 10 patients with pheochromocytoma before unilateral adrenalectomy, as well as in 10 healthy subjects (controls). Thirty days after surgery, OPN and END were evaluated again in 16 patients with adren... | ['Adrenal Cortex Neoplasms', 'Adrenal Gland Neoplasms', 'Adrenalectomy', 'Adult', 'Aged', 'Biomarkers', 'Case-Control Studies', 'Endostatins', 'Female', 'Humans', 'Hyperaldosteronism', 'Male', 'Middle Aged', 'Osteopontin', 'Pheochromocytoma', 'Young Adult'] | 21,968,021 | [['C04.588.322.078.265', 'C19.053.098.265', 'C19.053.347.500', 'C19.344.078.265'], ['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['E04.270.115'], ['M01.060.116'], ['M01.060.116.100'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D12.644.276.100.450.750', 'D12.776.46... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
How is the most severe health state being valued by the general population? | BACKGROUND: It has been reported that valuation of health states that are close to death, such as the most severe health state, can be affected by health state valuation procedure, and their utility values are difficult to predict. We examined how the most severe health states of Short Form-6 dimension (SF-6D) and Euro... | ['Adult', 'Aged', 'Cross-Sectional Studies', 'Female', 'Health Status Indicators', 'Humans', 'Male', 'Middle Aged', 'Psychological Distance', 'Quality of Life', 'Reproducibility of Results', 'Singapore', 'Terminally Ill', 'Visual Analog Scale'] | 25,344,269 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.145.813.630', 'F01.829.316.777'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Stereoselective nicotine-induced release of dopamine from striatal synaptosomes: concentration dependence and repetitive stimulation. | Using a sensitive perfusion system we have studied the nicotine-induced release of [3H]dopamine ([( 3H]DA) from striatal synaptosomes. Nicotine-evoked release was concentration dependent with an EC50 of 3.8 microM. The response to 1 microM nicotine was comparable to that to 16 mM K+; 10 microM veratridine evoked a larg... | ['Animals', 'Calcium', 'Corpus Striatum', 'Dopamine', 'Dose-Response Relationship, Drug', 'Male', 'Molecular Conformation', 'Nicotine', 'Potassium', 'Rats', 'Rats, Inbred Strains', 'Receptors, Nicotinic', 'Structure-Activity Relationship', 'Synaptosomes', 'Veratridine'] | 3,346,670 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A08.186.211.200.885.287.249.487'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['G07.690.773.875', 'G07.690.936.500'], ['G02.111.570.820'], ['D03.132.760.570', 'D03.383.725.518'], ['D01.268.549.550', 'D01.268.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intrapulmonary delivery of tumor necrosis factor agonist peptide augments host defense in murine gram-negative bacterial pneumonia. | Tumor necrosis factor alpha (TNF) has been shown to be an essential cytokine mediator of innate immunity in Klebsiella pneumonia. Recently, a TNF agonist peptide consisting of the 11-amino-acid TNF binding site (TNF70-80) has been shown to possess many of the leukocyte-activating properties of TNF without the associate... | ['Animals', 'Bronchoalveolar Lavage Fluid', 'Cytokines', 'Female', 'Immunity, Innate', 'Immunization, Passive', 'Klebsiella Infections', 'Klebsiella pneumoniae', 'Lung', 'Mice', 'Mice, Inbred CBA', 'Neutrophils', 'Peptide Fragments', 'Pneumonia, Bacterial', 'Tumor Necrosis Factor-alpha'] | 9,596,755 | [['B01.050'], ['E05.927.100.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G12.450.564'], ['E02.095.465.425.400.330', 'E05.478.550.520'], ['C01.150.252.400.310.503'], ['B03.440.450.425.425.600', 'B03.660.250.150.400.590'], ['A04.411'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Confirming pure-tone thresholds by auditory brainstem response in the geriatric population. | BACKGROUND: The aged people seeking otological consultation tend to increase for the purpose of applying for hearing disability certificate. When the subjective pure-tone thresholds (PTTs) are unreliable due to patient incooporation, the objective click auditory brainstem response (ABR) is used to confirm the hearing t... | ['Aged', 'Aged, 80 and over', 'Aging', 'Audiometry, Pure-Tone', 'Auditory Threshold', 'Evoked Potentials, Auditory, Brain Stem', 'Humans', 'Middle Aged', 'Prospective Studies', 'Regression Analysis'] | 12,135,195 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['E01.370.382.375.060.055'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['G07.265.216.500.370.300', 'G07.888.250.300', 'G11.561.200.500.370.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.5... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inflammatory cytokines in pediatric obstructive sleep apnea. | Pediatric obstructive sleep apnea (OSA) is associated with chronic systemic inflammation and with cognitive impairments. This study aimed to investigate the status of proinflammatory cytokines, particularly interleukin 17 (IL-17) and interleukin 23 (IL-23) and cognition in pediatric OSA.Controls and OSA children partic... | ['Biomarkers', 'Child', 'Child, Preschool', 'Cytokines', 'Female', 'Humans', 'Inflammation', 'Male', 'Prospective Studies', 'Sleep Apnea, Obstructive'] | 27,741,107 | [['D23.101'], ['M01.060.406'], ['M01.060.406.448'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C08.618.085.852.850', 'C10.886.425.800.750.850']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
CADASIL-associated Notch3 mutations have differential effects both on ligand binding and ligand-induced Notch3 receptor signaling through RBP-Jk. | Mutations in the NOTCH3 gene are the cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), a hereditary angiopathy leading to strokes and dementia. Pathogenic mutations remove or insert cysteine residues within epidermal growth factor (EGF) repeats in the extrace... | ['Adult', 'Animals', 'Calcium-Binding Proteins', 'Cells, Cultured', 'Cycloheximide', 'DNA-Binding Proteins', 'Dementia, Multi-Infarct', 'Epidermal Growth Factor', 'Humans', 'Immunoglobulin J Recombination Signal Sequence-Binding Protein', 'Intercellular Signaling Peptides and Proteins', 'Jagged-1 Protein', 'Ligands', '... | 15,350,543 | [['M01.060.116'], ['B01.050'], ['D12.776.157.125'], ['A11.251'], ['D03.383.621.808.240'], ['D12.776.260'], ['C10.228.140.300.150.477.200.199', 'C10.228.140.300.400.408', 'C10.228.140.300.775.200.200.199', 'C10.228.140.380.230.250', 'C14.907.253.092.477.200.199', 'C14.907.253.855.200.200.199', 'C23.550.513.355.250.200.1... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pediatricians' assessments of caries risk and need for a dental evaluation in preschool aged children. | BACKGROUND: Risk-based prioritization of dental referrals during well-child visits might improve dental access for infants and toddlers. This study identifies pediatrician-assessed risk factors for early childhood caries (ECC) and their association with the need for a dentist's evaluation.METHODS: A priority oral healt... | ['Checklist', 'Child, Preschool', 'Decision Support Techniques', 'Dental Care for Children', 'Dental Caries', 'Humans', 'Logistic Models', 'Multivariate Analysis', 'North Carolina', 'Pediatrics', "Practice Patterns, Physicians'", 'Referral and Consultation', 'Risk Assessment', 'Risk Factors'] | 22,559,270 | [['N05.715.360.300.179'], ['M01.060.406.448'], ['E05.245', 'L01.313.500.750.190'], ['E06.170.152', 'N02.421.240.190.215'], ['C07.793.720.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.71... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Overexpression of esterase D in kidney from trisomy 13 fetuses. | Human trisomy 13 (Patau syndrome) occurs in approximately 1 in 5,000 live births. It is compatible with life, but prolonged survival is rare. Anomalies often involve the urogenital, cardiac, craniofacial, and central nervous systems. It is possible that these abnormalities may be due to the overexpression of developmen... | ['Abnormalities, Multiple', 'Carboxylesterase', 'Carboxylic Ester Hydrolases', 'Chromosomes, Human, Pair 13', 'Female', 'Fetal Diseases', 'Humans', 'Kidney', 'Male', 'Phenotype', 'Syndrome', 'Trisomy'] | 8,213,811 | [['C16.131.077'], ['D08.811.277.352.100.100'], ['D08.811.277.352.100'], ['A11.284.187.520.300.370.375', 'G05.360.162.520.300.370.375'], ['C13.703.277', 'C16.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['G05.695'], ['C23.550.288.500'], ['C23.550.210.050.750', 'C23.550.210.182.500', 'G05.365.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Warming alone increased exotic snail reproduction and together with eutrophication influenced snail growth in native wetlands but did not impact plants. | Warming and eutrophication can have varying effects on exotic species performance and their interactions. These effects can vary with trophic level, but are rarely investigated simultaneously on exotic species from multiple trophic levels. To address this, we manipulated temperature, nutrients, and plant origin (native... | ['Animals', 'Biological Phenomena', 'Biomass', 'Eutrophication', 'Food', 'Herbivory', 'Introduced Species', 'Plants', 'Reproduction', 'Snails', 'Wetlands'] | 31,791,783 | [['B01.050'], ['G16'], ['G16.500.275.157.100', 'N06.230.124.100'], ['G16.500.285'], ['G07.203.300', 'J02.500'], ['F01.145.113.547.600', 'F01.145.407.758', 'G07.203.650.353.758'], ['B01.050.050.580', 'G16.500.275.157.049.400', 'N06.230.124.049.400'], ['B01.650'], ['G08.686.784'], ['B01.050.500.644.400.750'], ['G16.500.2... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The IgA subclass responses of human lymphocytes to B-cell activators. | The induction of IgA synthesis in normal peripheral blood lymphocytes cultured in the presence of 5 different B-cell activators was studied by immunofluorescence using monoclonal antibodies to the two subclasses. The surface phenotype of normal cells after overnight culture in the absence of mitogen showed a mean ratio... | ['Antigens, Surface', 'B-Lymphocytes', 'Fluorescent Antibody Technique', 'Humans', 'Immunoglobulin A', 'Lymphocyte Activation', 'Lymphocytes', 'Phenotype', 'T-Lymphocytes'] | 3,542,813 | [['D23.050.301'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High sensitive DNA typing approaches for the analysis of forensic evidence: comparison of nested variable number of tandem repeats (VNTR) amplification and a short tandem repeats (STR) polymorphism. | The approach of using nested primers for the APO B variable number of tandem repeats (VNTR) increases the sensitivity of the polymerase chain reaction (PCR) to single cell level. Different experiments and a comparison to the short tandem repeats (STR) system VWA were carried out, to determine the applicability of this ... | ['Base Sequence', 'Blood Stains', 'DNA', 'Forensic Medicine', 'Genotype', 'Humans', 'Male', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'Repetitive Sequences, Nucleic Acid', 'Sensitivity and Specificity', 'Sperm Count', 'Spermatozoa'] | 8,063,275 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['I01.198.780.937.206'], ['D13.444.308'], ['H02.403.330', 'I01.198.780.937'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['E05.393.620.500'], ['G05.365.795'], ['G02.111.570.080.708', 'G05.360.080.708'], ['E05.318.370.800... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
The cerebellum and its contribution to complex tasks in higher primates: a comparative perspective. | Many aspects of the involvement of the cerebellum in motor control and cognition are still quite unclear or relatively unexplored. In particular, very little is known about the evolution of cerebellar contribution to complex behavior in higher primate species. In this paper, we provide an overview of existing and ongoi... | ['Animals', 'Behavior, Animal', 'Cerebellum', 'Data Interpretation, Statistical', 'Female', 'Functional Laterality', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Motor Skills', 'Pan troglodytes', 'Physiology, Comparative', 'Predatory Behavior', 'Psychomotor Performance'] | 19,926,082 | [['B01.050'], ['F01.145.113'], ['A08.186.211.132.810.428.200'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['F02.830.297.425', 'G11.561.225.425'], ['L01.224.308'], ['E01.370.350.825.500'], ['F02.808.260'], ['B01.050.150.900.649.313.988.400.112.400.620'],... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Gene transfer of immunomodulatory peptides correlates with heme oxygenase-1 induction and enhanced allograft survival. | BACKGROUND: Decapeptides derived from human HLA class I sequences have been shown to prolong allograft survival. The mechanism of action of these peptides has been uncertain, because they act in an MHC unrestricted manner. Recently, it was found that these peptides bind heme oxygenase 1 (HO-1). In the present study, we... | ['Animals', 'Dose-Response Relationship, Drug', 'Enzyme Induction', 'Female', 'Gene Transfer Techniques', 'Graft Rejection', 'Graft Survival', 'Heart Transplantation', 'Heme Oxygenase (Decyclizing)', 'Heme Oxygenase-1', 'Humans', 'Injections', 'Membrane Proteins', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred CBA', 'Pept... | 10,653,390 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['G05.308.320.200'], ['E05.393.350'], ['G12.875.545.328'], ['G12.875.545.340'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['D08.811.682.690.708.410'], ['D08.811.682.690.708.410.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.53... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The well-being and mental health of male and female hospital doctors in Germany. | This study focuses on the associations between subjective well-being and mental health. In addition, gender differences are evaluated. The research was conducted as a cross-sectional online survey using a standardized questionnaire to assess physicians' mental health and well-being. Results have shown moderate scores f... | ['Cross-Sectional Studies', 'Female', 'Germany', 'Humans', 'Male', 'Medical Staff, Hospital', 'Mental Health', 'Personal Satisfaction', 'Socioeconomic Factors', 'Surveys and Questionnaires'] | 25,985,556 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.630.490', 'M01.526.485.740.422', 'N02.360.630.490', 'N02.360.740.422'], ['F02.418', 'N01.400.500'], ['F01.145.677'], ['I01.880.853.996', 'N01.824'], ['E05.318.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Neuroinfectious diseases at a European neurological tertiary care center: one-third of patients require treatment in the neurological intensive care unit. | BACKGROUND AND PURPOSE: Studies on the impact of infectious diseases affecting the nervous system are sparse.METHODS: All patients with neuroinfectious diseases (NIDs) who were treated at our Department of Neurology from 2005 until 2009 were retrospectively analyzed.RESULTS: Patients with NIDs required treatment at the... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Central Nervous System Infections', 'Female', 'Germany', 'Humans', 'Intensive Care Units', 'Male', 'Middle Aged', 'Retrospective Studies', 'Tertiary Care Centers', 'Young Adult'] | 24,506,319 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.207', 'C10.228.228'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Infection with herpes simplex virus and cell-mediated immunity after marrow transplant. | The relationship between herpes simplex virus (HSV) infection and specific cell-mediated immunity was investigated in 141 patients before and for the first four months after marrow transplant. Sixty-two (82%) of 76 seropositive patients but only one of 65 seronegative patients developed HSV infection. Lymphocyte respon... | ['Antigens, Viral', 'Antilymphocyte Serum', 'Bone Marrow Transplantation', 'Concanavalin A', 'Graft vs Host Reaction', 'Herpes Simplex', 'Humans', 'Immunity, Cellular', 'Lymphocyte Activation', 'Phytohemagglutinins', 'Simplexvirus', 'T-Lymphocytes', 'Transplantation, Homologous'] | 6,255,035 | [['D23.050.327'], ['A12.207.152.846.500.203', 'D12.776.124.486.485.114.573.203', 'D12.776.124.790.651.114.573.203', 'D12.776.377.715.548.114.573.203', 'D20.215.401.203'], ['E02.095.147.725.040', 'E04.936.580.040'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['G12.875.402'], ['C01.925.256.466.382', 'C01.925.825.320... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Performance of a halo ion trap mass analyzer with exit slits for axial ejection. | The halo ion trap (IT) was modified to allow for axial ion ejection through slits machined in the ceramic electrode plates rather than ejecting ions radially to a center hole in the plates. This was done to preserve a more uniform electric field for ion analysis. An in-depth evaluation of the higher-order electric fiel... | ['Algorithms', 'Ceramics', 'Heptanes', 'Mass Spectrometry', 'Methylene Chloride', 'Miniaturization', 'Toluene'] | 21,472,596 | [['G17.035', 'L01.224.050'], ['J01.637.153'], ['D02.455.326.146.485'], ['E05.196.566'], ['D02.455.526.439.642'], ['J01.897.520'], ['D02.455.426.559.389.832']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
[Characteristics of smoking, drinking, dietary habits, and physical exercise in health behavioral models]. | Various kinds of preventive health behaviors are promoted by health education. The extent of behavioral modification achieved, however, obviously differs from individual to individual according to habits, one of the reasons being the characteristics of various health habits are perceived differently. This cross-section... | ['Adult', 'Alcohol Drinking', 'Cross-Sectional Studies', 'Exercise', 'Feeding Behavior', 'Female', 'Health Behavior', 'Humans', 'Male', 'Middle Aged', 'Models, Psychological', 'Smoking'] | 8,835,014 | [['M01.060.116'], ['F01.145.317.269'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G11.427.410.698.277', 'I03.350'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.599.695'], ['F01.1... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Incidentally discovered pituitary lesions: high frequency of macroadenomas and hormone-secreting adenomas - results of a prospective study. | OBJECTIVE: With increasing use of computed tomography and magnetic resonance imaging, pituitary adenomas are being discovered incidentally with increasing frequency. However, limited data are available concerning the clinical importance and natural history of such 'incicentalomas'. We have undertaken a prospective stud... | ['Adenoma', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Follicle Stimulating Hormone', 'Follow-Up Studies', 'Gonadotropin-Releasing Hormone', 'Humans', 'Insulin-Like Growth Factor Binding Protein 3', 'Insulin-Like Growth Factor I', 'Luteinizing Hormone', 'Magnetic Resonance Imaging', 'Male', 'Middle ... | 10,469,480 | [['C04.557.470.035'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D06.472.699.327.740.320', 'D12.644... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Evaluating the efficacy of a program to enhance college students' self-regulation learning processes and learning strategies]. | The present study examines the efficacy of a program designed to enhance college students'learning processes and study strategies. The program was organised around a number of letters written by a freshman, Gerv?sio (Ros?rio, N??ez, & Gonz?lez-Pienda, 2006), telling about his new experiences, troubles, and successes in... | ['Adolescent', 'Adult', 'Attitude', 'Cognition', 'Female', 'Humans', 'Learning', 'Male', 'Program Development', 'Program Evaluation', 'Social Control, Informal', 'Social Facilitation', 'Students', 'Universities'] | 17,617,980 | [['M01.060.057'], ['M01.060.116'], ['F01.100'], ['F02.463.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['N04.452.760'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['I01.880.630'], ['F01.145.813.655'], ['M01.848'], ['I02.783.830', 'J03.832.830']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Detection of apoptosis-related factors and apoptotic cells in ameloblastomas: analysis by immunohistochemistry and an in situ DNA nick end-labelling method. | To clarify the possible role of apoptosis in odontogenic epithelium, apoptosis-related factors and apoptotic cells were examined by immunohistochemistry and an in situ DNA nick end-labelling method. Expression of bcl-2 protein was detected in both normal and neoplastic odontogenic epithelium, whereas expression of p53 ... | ['Ameloblastoma', 'Apoptosis', 'Cell Count', 'Cell Death', 'Cell Differentiation', 'Coloring Agents', 'DNA, Neoplasm', 'Enamel Organ', 'Epithelium', 'Humans', 'Immunoenzyme Techniques', 'Immunohistochemistry', 'In Situ Hybridization', 'Jaw Neoplasms', 'Lewis Blood Group Antigens', 'Proto-Oncogene Proteins c-bcl-2', 'To... | 9,385,580 | [['C04.557.695.065'], ['G04.146.954.035'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.146'], ['G04.152'], ['D27.720.233'], ['D13.444.308.425'], ['A14.549.167.900.720.265'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Spontaneous regression of pulmonary metastases from hypernephroma: report of a case and review of literature (author's transl)]. | Until now there are reported some 60 cases of spontaneous regression of pulmonary metastases from hypernephroma. An own case is shown up: There was taken nephrectomy and following local radiation of hypernephroma in a 59 years old male patient in spite of pulmonary metastases. 8 months after operation these metastases ... | ['Adenocarcinoma', 'Follow-Up Studies', 'Humans', 'Kidney Neoplasms', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Metastasis', 'Neoplasm Regression, Spontaneous', 'Postoperative Complications', 'Radiotherapy, High-Energy', 'Time Factors'] | 412,043 | [['C04.557.470.200.025'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['C04.588.894.797.520', 'C08.381.540', 'C08.7... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Heterogeneity of juvenile hormone binding compounds in fat bodies of a cockroach. | Fat bodies of adult vitellogenic or non-vitellogenic females and those of adult males contain 2 populations of saturable JH binding compounds. The respective Kd vales are 2-5 x 10(-9) M and 1-4 x 10(-8) M. Fat bodies of penultimate nymphs, hemolymph of any animal, and midgut epithelia contain one saturable JH binder w... | ['Adipose Tissue', 'Animals', 'Binding, Competitive', 'Chromatography, Ion Exchange', 'Cockroaches', 'Fat Body', 'Female', 'Juvenile Hormones', 'Kinetics', 'Male', 'Receptors, Cell Surface'] | 6,276,244 | [['A10.165.114'], ['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['E05.196.181.400.383'], ['B01.050.500.131.617.140'], ['A13.365'], ['D06.472.445.573.666'], ['G01.374.661', 'G02.111.490'], ['D12.776.543.750']] | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
3D-finite element model of the human cochlea including fluid-structure couplings. | The propagation of acoustic waves in the inner ear in vivo could not be quantified completely yet. This is in particular true in conjunction with the micromechanical structures of the organ of Corti, though these data are important for the explanation and discussion of clinical measurements like otoacoustic emissions a... | ['Biomechanical Phenomena', 'Cochlea', 'Computer Simulation', 'Finite Element Analysis', 'Humans', 'Microradiography', 'Models, Biological', 'Perilymph', 'Pressure', 'Sound', 'Tomography, X-Ray'] | 10,529,652 | [['G01.154.090', 'G01.374.089'], ['A09.246.300.246'], ['L01.224.160'], ['E05.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.510'], ['E05.599.395'], ['A12.207.270.517.678'], ['G01.374.715'], ['G01.750.770.776'], ['E01.370.350.700.810', 'E01.370.350.825.810']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Molecular basis of increased serum resistance among pulmonary isolates of non-typeable Haemophilus influenzae. | Non-typeable Haemophilus influenzae (NTHi), a common commensal of the human pharynx, is also an opportunistic pathogen if it becomes established in the lower respiratory tract (LRT). In comparison to colonizing isolates from the upper airway, LRT isolates, especially those associated with exacerbations of chronic obstr... | ['Blood Bactericidal Activity', 'Genes, Bacterial', 'Genetic Variation', 'Haemophilus Infections', 'Haemophilus influenzae', 'Host-Pathogen Interactions', 'Humans', 'Immunity, Innate', 'Lung', 'Respiratory Tract Infections'] | 21,253,576 | [['G09.188.100', 'G12.450.564.204'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.365'], ['C01.150.252.400.700.433'], ['B03.440.450.600.450.330', 'B03.660.250.550.290.330'], ['G06.462', 'G16.527.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.564'], ['A0... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Privatization and Psychoanalysis: The Impact of Neo-liberalism on Freud's Tool of Social Justice. | The paper outlines the historical links between psychoanalysis, social progressivism and the political Left. It then details the process by which those links were undone such that today psychoanalysis and mental health services in general are alienated from their radical roots. The paper posits this process of alienati... | ['Adult', 'Female', 'Freudian Theory', 'Humans', 'Politics', 'Privatization', 'Psychoanalysis', 'Social Justice'] | 26,211,328 | [['M01.060.116'], ['F02.739.794.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.738'], ['N04.452.633.780'], ['F04.096.544.779'], ['I01.880.604.473.700', 'K01.752.566.479.830.750', 'N03.706.437.700', 'N05.350.958.750']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Release of arylsulfatase A but not B from rat mast cells by noncytolytic secretory stimuli. | The net percentage of release of arylsulfatase activity from purified rat mast cells induced by rabbit anti-rat F(ab')2 was consistently only about 1/3 that of histamine. Isoelectric focusing of the released and residual arylsulfatase activities demonstrated specific release of the A type without B and a net percentage... | ['Acetylglucosaminidase', 'Animals', 'Arylsulfatases', 'Calcimycin', 'Cytoplasmic Granules', 'Female', 'Heparin', 'Histamine', 'Histamine Release', 'Immunoglobulin Fab Fragments', 'Isoelectric Focusing', 'Male', 'Mast Cells', 'Rabbits', 'Rats', 'Sulfatases'] | 81,231 | [['D08.811.277.450.483.180.500'], ['B01.050'], ['D08.811.277.352.827.070'], ['D03.633.100.221.173'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['D09.698.373.400'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['G12.350'], ['D12.644.541.500.650', 'D12.776.12... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
pH sensitivity of chlorophyll fluorescence quenching is determined by the detergent/protein ratio and the state of LHCII aggregation. | Here we show how the protein environment in terms of detergent concentration/protein aggregation state, affects the sensitivity to pH of isolated, native LHCII, in terms of chlorophyll fluorescence quenching. Three detergent concentrations (200, 20 and 6ìM n-dodecyl â-d-maltoside) have been tested. It was found that at... | ['Chlorophyll', 'Detergents', 'Fluorescence', 'Hydrogen-Ion Concentration', 'Light-Harvesting Protein Complexes', 'Photosystem II Protein Complex', 'Protein Conformation', 'Protein Multimerization'] | 24,321,504 | [['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['D27.720.877.265', 'J01.516.381'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['G02.300'], ['D05.500.562.488.490', 'D08.811.600.710.490', 'D12.776.543.930.500.490', 'D12.776.765.199.750.750.490'], ['D05.500.562.488.750', 'D08.811.600.... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A novel gene, CRR9, which was up-regulated in CDDP-resistant ovarian tumor cell line, was associated with apoptosis. | In the screening for cisplatin (CDDP)-resistance related genes by a mRNA differential display method, we detected some increased bands in CDDP resistant ovarian tumor cell line 2008/C13*5.25. One of them, named DD9, was a positive fragment on Northern blot analysis. We cloned it as a full length cDNA by 5'RACE and foun... | ['Amino Acid Sequence', 'Antineoplastic Agents', 'Apoptosis', 'Base Sequence', 'Blotting, Northern', 'Cisplatin', 'Cloning, Molecular', 'DNA, Complementary', 'Dose-Response Relationship, Drug', 'Drug Resistance, Neoplasm', 'Female', 'Gene Expression Profiling', 'Humans', 'Membrane Proteins', 'Molecular Sequence Data', ... | 11,162,647 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D27.505.954.248'], ['G04.146.954.035'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Using talking lights to assist brain-injured patients with daily inpatient therapeutic schedule. | OBJECTIVES: To test the ability of patients with brain injury to use a patient locator and minder (PLAM) system to assist in their adherence to therapy schedules.PARTICIPANTS: Five patients with acquired brain injury who were inpatients on an acute rehabilitation floor of a rehabilitation hospital.MEASURES: The number ... | ['Adult', 'Aged', 'Appointments and Schedules', 'Brain Injuries', 'Cues', 'Feasibility Studies', 'Fluorescence', 'Hospital Units', 'Humans', 'Lighting', 'Microcomputers', 'Middle Aged', 'Pilot Projects', 'Regression Analysis', 'Rehabilitation Centers', 'Reminder Systems'] | 11,346,450 | [['M01.060.116'], ['M01.060.116.100'], ['N04.452.095'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['F02.463.425.234'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['N02.278.388'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Distinct pattern of direct immunofluorescence in livedoid vasculopathy. | There are discrepancies in findings on direct immunofluorescence (DIF) examinations for livedoid vasculopathy. We sought to assess the usefulness of DIF examinations as an adjunct to the diagnosis of livedoid vasculopathy. Clinical data and findings on DIF examinations were retrospectively collected from our immunofluo... | ['Adult', 'Aged', 'Biomarkers', 'Blood Vessels', 'Complement C3', 'Female', 'Fibrinogen', 'Fluorescent Antibody Technique, Direct', 'Humans', 'Immunoglobulin A', 'Immunoglobulin G', 'Immunoglobulin M', 'Male', 'Middle Aged', 'Retrospective Studies', 'Skin', 'Skin Diseases, Vascular', 'Vasculitis', 'Young Adult'] | 20,075,710 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101'], ['A07.015'], ['D12.776.124.050.140', 'D12.776.124.486.274.250'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['E01.370.225.500.607.512.240.300', 'E01.370.225.750.551.512.240.300', 'E05.200.500.607.512.240.300', 'E05.200.750.551.51... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sero-epidemiology of hepatitis A in black South African children. | A community-based sero-epidemiological survey was undertaken to determine the age-specific prevalence rates of hepatitis A virus (HAV) infection in a representative sample of 782 urban black children aged from newborn to 13 years. Among children aged 0-5 months, the prevalence of anti-HAV was 68.8% (95% confidence inte... | ['African Americans', 'African Continental Ancestry Group', 'Age Distribution', 'Child', 'Child, Preschool', 'Female', 'Hepatitis A', 'Hepatitis A Antibodies', 'Hepatitis Antibodies', 'Hepatovirus', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Prevalence', 'Seroepidemiologic Studies', 'South Africa'] | 8,191,332 | [['M01.686.508.100.100', 'M01.686.754.100'], ['M01.686.508.100'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.406'], ['M01.060.406.448'], ['C01.925.440.420', 'C01.925.782.687.359.500', 'C06.552.380.705.422'], ['D12.776.124.486.485.114.254.450.251', 'D12.776.124.790.651.114.254.450.251', 'D12.776.37... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Effects of inhaled beclomethasone dipropionate on serum IgE levels and clinical symptoms in atopic asthma. | BACKGROUND: A high serum immunoglobulin (Ig)E level is considered a potent predictor for the development of asthma and IgE is targeted for treatment of asthma. Although inhaled corticosteroids are well established in the treatment of asthma, the effects of inhaled corticosteroids on serum IgE levels in asthma remain un... | ['Administration, Inhalation', 'Adult', 'Asthma', 'Beclomethasone', 'Double-Blind Method', 'Eosinophils', 'Female', 'Humans', 'Immunoglobulin E', 'Male'] | 10,202,343 | [['E02.319.267.050'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D04.210.500.745.432.769.125', 'D04.210.500.883.154'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular modeling of BAD complex resided in a mitochondrion integrating glycolysis and apoptosis. | BAD (Bcl-2 antagonist of cell death) and GK (glucokinase) reside in a mitochondrial complex together with PKA and PP1 catalytic units (PKAc and PP1c) and WAVE-1 that integrates glycolysis and apoptosis. Our research results reveal that BAD is phosphorylated and inactivated on Ser 75 in a BAD-Bcl-xL complex by PKA (targ... | ['Amino Acid Sequence', 'Apoptosis', 'Cyclic AMP-Dependent Protein Kinases', 'Glucokinase', 'Glycolysis', 'Humans', 'Liver', 'Mitochondria', 'Models, Molecular', 'Molecular Sequence Data', 'Multiprotein Complexes', 'Phosphorylation', 'Protein Phosphatase 1', 'Sequence Alignment', 'Wiskott-Aldrich Syndrome Protein Famil... | 20,540,951 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G04.146.954.035'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['D08.811.913.696.620.250'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['A11.284.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A polysomnographic and clinical report on sleep-related injury in 100 adult patients. | In 100 consecutive adults who came to a sleep disorders center complaining of repeated nocturnal injury, polysomnographic study identified five disorders: night terrors/sleepwalking (N = 54), REM sleep behavior disorder (N = 36), dissociative disorders (N = 7), nocturnal seizures (N = 2), and sleep apnea (N = 1). Ninet... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Clonazepam', 'Dissociative Disorders', 'Female', 'Humans', 'MMPI', 'Male', 'Mental Disorders', 'Middle Aged', 'Sleep', 'Sleep Apnea Syndromes', 'Sleep Wake Disorders', 'Sleep, REM', 'Somnambulism', 'Wounds and Injuries'] | 2,764,174 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['D03.633.100.079.080.070.150'], ['F03.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.647.513.607'], ['F03'], ['M01.060.116.630'], ['F02.830.855', 'G11.561.803'], ['C08.618.085.852', 'C10.886.425.800.750'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Allele frequencies of 10 STR loci in Koreans. | Allele frequencies for the 10 STR loci, D6S1043, D9S925, D7S821, D4S2368, D21S2055, GATA193A07, D12S391, D10S2326, D15S822 and D18S51 were obtained from a sample of 217-310 unrelated Koreans. In this study, 2 out of the 10 loci did not meet Hardy-Weinberg expectation. The combined probability of identity for 10 loci te... | ['DNA Fingerprinting', 'Gene Frequency', 'Genetics, Population', 'Humans', 'Korea', 'Tandem Repeat Sequences'] | 15,013,178 | [['E05.318.740.225.500.500', 'E05.393.290', 'I01.198.780.937.375', 'N04.452.910.099.750'], ['G05.330'], ['H01.158.273.343.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.557', 'Z01.586.407'], ['G02.111.570.080.708.800', 'G05.360.080.708.800', 'G05.360.340.024.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
An optimized molecular method for detection of influenza A virus using improved generic primers and concentration of the viral genomic RNA and nucleoprotein complex. | For reported primer sets used to detect influenza A viruses (IAVs), we verified the nucleotide identities with 9,103 complete sequences of matrix (M) genes. At best, only 93.2% and 85.3% of the sequences had a 100% match with reported forward and reverse primers, respectively. Therefore, we designed new degenerate forw... | ['Animals', 'DNA Primers', 'Gene Expression Regulation, Viral', 'Genomics', 'Influenza A virus', 'Nucleoproteins', 'RNA, Viral', 'Real-Time Polymerase Chain Reaction', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sensitivity and Specificity'] | 30,795,722 | [['B01.050'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.308.385'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['B04.820.480.968.405.400'], ['D12.776.664'], ['D13.444.735.828'], ['E05.393.620.500.706'], ['E05.393.620.500.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Observation units: boom or bust for emergency medicine. | Observation units (OBS) are becoming a common addition to the emergency department. The diagnostic and socioeconomic categories of patients admitted to the OBS unit resemble those seen in the emergency department. There are many advantages and disadvantages in establishing such a unit. Although OBS units provide improv... | ['Costs and Cost Analysis', 'Decision Making', 'Emergency Medical Services', 'Emergency Service, Hospital', 'Hospital Design and Construction', 'Hospital Units', 'Humans', 'Insurance, Health, Reimbursement', 'Patient Advocacy', 'Quality Assurance, Health Care'] | 2,212,570 | [['N03.219.151'], ['F02.463.785.373'], ['N02.421.297'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['J01.086.339.250', 'N02.278.200.403'], ['N02.278.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.480', 'N03.219.521.710'], ['I01.880.604.631', 'N03.706.678'],... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
Peer and teacher ratings of third- and fourth-grade children's social behavior as a function of early maternal employment. | BACKGROUND: One of the more controversial issues related to maternal employment in the United States concerns the timing of entry into the workforce and its effect on children, particularly during the first year of the child's life. Some studies show deleterious effects on children, such as increases in aggression and ... | ['Affect', 'Child', 'Child Behavior Disorders', 'Child Care', 'Employment', 'Ethnic Groups', 'Faculty', 'Follow-Up Studies', 'Humans', 'Male', 'Mothers', 'Observer Variation', 'Peer Group', 'Social Behavior', 'Socioeconomic Factors', 'Surveys and Questionnaires', 'Time Factors'] | 12,751,841 | [['F01.470.047'], ['M01.060.406'], ['F03.625.141'], ['I01.880.787.293.360', 'N02.421.088'], ['N01.824.245'], ['M01.686.754', 'N01.224.317'], ['M01.526.702.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.500.... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Effects of some psychotropic drugs on the b-wave of the electroretinogram in isolated rabbit retina. | The role of dopaminergic and cholinergic functions in the genesis of an electroretinogram is unclear. The present study was carried out to elucidate the direct actions of some psychotropic drugs in isolated rabbit retinas. Methamphetamine and apomorphine decreased dose-dependently the b-wave amplitude at a dose of 10(-... | ['Animals', 'Dose-Response Relationship, Drug', 'Electroretinography', 'In Vitro Techniques', 'Male', 'Psychotropic Drugs', 'Rabbits', 'Retina'] | 3,367,551 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.380.225', 'E01.370.405.270'], ['E05.481'], ['D27.505.954.427.700'], ['B01.050.150.900.649.313.968.700'], ['A09.371.729']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Recurrent type B intramural hematoma progressed into type A acute aortic dissection in a young otherwise healthy woman: are there unknown background factors? | Intramural hematoma is reported with increasing frequency but the recurrence after complete resolution is rarely reported. We herewith describe a case of type B intramural hematoma in an otherwise healthy 39-year-old woman showing unusual clinical course in which acute aortic dissection developed three months after com... | ['Acute Disease', 'Adult', 'Aneurysm, Dissecting', 'Antihypertensive Agents', 'Aortic Aneurysm', 'Aortic Diseases', 'Aortography', 'Blood Vessel Prosthesis Implantation', 'Disease Progression', 'Female', 'Hematoma', 'Humans', 'Recurrence', 'Severity of Illness Index', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 17,669,834 | [['C23.550.291.125'], ['M01.060.116'], ['C14.907.055.050'], ['D27.505.954.411.162'], ['C14.907.055.239', 'C14.907.109.139'], ['C14.907.109'], ['E01.370.350.700.060.070', 'E01.370.370.050.070'], ['E04.100.814.868.500', 'E04.650.200'], ['C23.550.291.656'], ['C23.550.414.838'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. | BACKGROUND: Obesity is related to multiple cardiovascular disease (CVD) risk factors as well as CVD and has a strong familial component. We tested for association between SNPs on the Affymetrix 100K SNP GeneChip and measures of adiposity in the Framingham Heart Study.METHODS: A total of 1341 Framingham Heart Study part... | ['Adiposity', 'Adult', 'Body Mass Index', 'Cardiovascular Diseases', 'Cohort Studies', 'Female', 'Genetic Markers', 'Genome, Human', 'Genotype', 'Humans', 'Male', 'Middle Aged', 'Phenotype', 'Polymorphism, Single Nucleotide', 'Wrist'] | 17,903,300 | [['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C14'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D23.101.387', 'G05.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dietary copper-fructose interactions alter gut microbial activity in male rats. | Dietary copper-fructose interactions contribute to the development of nonalcoholic fatty liver disease (NAFLD). Gut microbiota play critical roles in the pathogenesis of NAFLD. The aim of this study was to determine the effect of different dietary doses of copper and their interactions with high fructose on gut microbi... | ['Animals', 'Bacteria', 'Copper', 'Dietary Sugars', 'Dose-Response Relationship, Drug', 'Dysbiosis', 'Fructose', 'Gastrointestinal Microbiome', 'Host-Pathogen Interactions', 'Ileum', 'Liver', 'Male', 'Non-alcoholic Fatty Liver Disease', 'Pancreatitis-Associated Proteins', 'Rats, Sprague-Dawley', 'Tight Junction Protein... | 29,025,734 | [['B01.050'], ['B03'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D09.301.831', 'D09.947.500', 'G07.203.300.362.831', 'J02.500.362.831'], ['G07.690.773.875', 'G07.690.936.500'], ['C23.550.308'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Nutritional stress of adult female tsetse flies (Diptera: Glossinidae) affects the susceptibility of their offspring to trypanosomal infections. | The epidemiology of tsetse-transmitted trypanosomiasis depends, among other factors, on the proportion of infected flies in a tsetse population. A wide range of intrinsic and extrinsic factors seem to determine the ability of a tsetse fly to become infected and to transmit the parasite. In this paper, we investigated t... | ['Animals', 'Disease Susceptibility', 'Feeding Behavior', 'Female', 'Trypanosoma brucei brucei', 'Trypanosoma congolense', 'Trypanosomiasis', 'Tsetse Flies'] | 19,445,895 | [['B01.050'], ['C23.550.291.687', 'G07.100.250'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.268.475.868.887.080'], ['B01.268.475.868.887.128'], ['C01.610.752.300.900'], ['B01.050.500.131.617.720.500.500.750.400.700']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fetal plasma concentrations after intraamniotic sufentanil in chronically instrumented pregnant sheep. | BACKGROUND: Rapid progress is being made in fetal surgery. Because the fetus is capable of pain perception after the 26th week of gestation, adequate postoperative fetal pain management is essential. The preferred approach would provide fetal analgesia without affecting the mother. Intraamniotically administered sufent... | ['Amnion', 'Analgesics, Opioid', 'Animals', 'Blood Gas Analysis', 'Female', 'Fetus', 'Hemodynamics', 'Injections', 'Pregnancy', 'Regional Blood Flow', 'Sheep', 'Sufentanil', 'Uterus'] | 12,766,649 | [['A10.615.284.277', 'A16.254.750.277'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['B01.050'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['A16.378'], ['G09.330.380'], ['E02.319.267.530'], ['G08.686.784.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Placental and fetal disposition of mercuric ions in rats exposed to methylmercury: role of Mrp2. | Methylmercury is a prevalent environmental toxicant that can have deleterious effects on a developing fetus. Previous studies indicate that the multidrug resistance-associated protein 2 (Mrp2) is involved in renal and hepatic export of mercuric ions. Therefore, we hypothesize that Mrp2 is also involved in export of mer... | ['ATP-Binding Cassette Transporters', 'Amniotic Fluid', 'Animals', 'Environmental Pollutants', 'Feces', 'Female', 'Fetus', 'Kidney', 'Liver', 'Mercury', 'Methylmercury Compounds', 'Placenta', 'Pregnancy', 'Rats', 'Rats, Mutant Strains', 'Rats, Wistar', 'Uterus'] | 23,059,061 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['A12.098', 'A16.378.149'], ['B01.050'], ['D27.888.284'], ['A12.459'], ['A16.378'], ['A05.810.453'], ['A03.620'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['D02.691.750.100.738'], ['A16.710'], ['G08.686.784.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cardiovascular magnetic resonance findings in repaired anomalous left coronary artery to pulmonary artery connection (ALCAPA). | BACKGROUND: Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare coronary artery anomaly. This study shows the role of cardiovascular magnetic resonance (CMR) in assessing young patients following surgical repair of ALCAPA.METHODS: 6 patients, aged 9-21 years, with repaired ALCAPA (... | ['Adolescent', 'Cardiac Catheterization', 'Cardiac Surgical Procedures', 'Child', 'Contrast Media', 'Coronary Circulation', 'Coronary Vessel Anomalies', 'Coronary Vessels', 'Female', 'Fibrosis', 'Humans', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Magnetic Resonance Imaging, Cine', 'Male'... | 21,575,211 | [['M01.060.057'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E04.100.376', 'E04.928.220'], ['M01.060.406'], ['D27.505.259.500', 'D27.720.259'], ['G09.330.100.324'], ['C14.240.400.210', 'C14.280.400.210', 'C16.131.240.400.210'], ['A07.015.114.269', 'A07.015.908.194'], ['C23.550.355'], ['B01.050.150.900.649... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Removal of Acid Blue25 from aqueous solutions using Bengal gram fruit shell (BGFS) biomass. | The feasibility for the removal of Acid Blue25 (AB25) by Bengal gram fruit shell (BGFS), an agricultural by-product, has been investigated as an alternative for high-cost adsorbents. The impact of various experimental parameters such as dose, different dye concentration, solution pH, and temperature on the removal of A... | ['Adsorption', 'Anthraquinones', 'Biodegradation, Environmental', 'Biomass', 'Cicer', 'Coloring Agents', 'Fruit', 'Water Pollutants, Chemical'] | 27,739,901 | [['G01.030', 'G02.020'], ['D02.455.426.559.847.117.159', 'D02.806.100', 'D04.615.117.159'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['G16.500.275.157.100', 'N06.230.124.100'], ['B01.650.940.800.575.912.250.401.150'], ['D27.720.233'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['D27.888.284.903.655']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Endometrial expression of selected transcripts involved in prostaglandin synthesis in cows with endometritis. | Several cytokines and prostaglandins play an important role in preparing the endometrium for implantation and mediating pro-inflammatory events. The aim of the present study was to examine mRNA expression of interleukin 1alpha (IL-1alpha), interleukin receptor antagonist (IL-1-RN), cytosolic prostaglandin E synthase (c... | ['Animals', 'Cattle', 'Cattle Diseases', 'Cytosol', 'Endometritis', 'Endometrium', 'Epithelium', 'Estrous Cycle', 'Female', 'Gene Expression', 'Interleukin 1 Receptor Antagonist Protein', 'Interleukin-1alpha', 'Intramolecular Oxidoreductases', 'Lipocalins', 'Microsomes', 'Postpartum Period', 'Prostaglandin-E Synthases'... | 19,162,311 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['C13.351.500.056.750.249', 'C13.351.500.852.299'], ['A05.360.319.679.490'], ['A10.272'], ['G08.686.195'], ['G05.297'], ['D12.644.276.374.460', 'D12.776.467.374.460', 'D23.529.374.4... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Relationship Between Circulating Acetaminophen-Protein Adduct Concentrations and Alanine Aminotransferase Activities in Patients With and Without Acetaminophen Overdose and Toxicity. | INTRODUCTION: Measurement of serum acetaminophen-protein adducts (APAP-CYS) has been suggested to support or refute a diagnosis of acetaminophen (APAP)-induced hepatotoxicity when ingestion histories are unreliable or unavailable and when circulating APAP concentrations are low or undetectable. Non-APAP overdose patien... | ['Acetaminophen', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Alanine Transaminase', 'Blood Proteins', 'Drug Overdose', 'Female', 'Humans', 'Male', 'Middle Aged', 'Young Adult'] | 30,980,348 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.811.913.477.700.100'], ['D12.776.124'], ['C25.775.383', 'E02.319.306.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.060.116.815']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Vision screening at 8 and 18 months. Steering Committee of Oxford Region Child Development Project. | OBJECTIVE: To determine the effectiveness of an existing screening programme based in the community for ocular and vision defects in infants considered at increased risk of such defects.DESIGN: Children with ocular or vision defect by the age of 2 were ascertained by searching records. Those from populations at high ri... | ['Age Factors', 'Birth Weight', 'England', 'Humans', 'Infant', 'Risk Factors', 'Sensitivity and Specificity', 'Vision Disorders', 'Vision Screening'] | 2,507,064 | [['N05.715.350.075', 'N06.850.490.250'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05... | ['Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Prevalence of genital mycoplasmas in asymptomatic male partners of women diagnosed as having chlamydial infections. | We examined 209 asymptomatic male partners of women diagnosed as having chlamydial infections for the prevalence of Neisseria gonorrhoeae, Chlamydia trachomatis, Mycoplasma genitalium, Mycoplasma hominis, Ureaplasma urealyticum, and Ureaplasma parvum in their first-voided urine (FVU) by nucleic acid amplification tests... | ['Adolescent', 'Adult', 'Aged', 'Chlamydia trachomatis', 'Female', 'Gram-Negative Bacterial Infections', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Neisseria gonorrhoeae', 'Prevalence', 'Sexual Partners', 'Sexually Transmitted Diseases, Bacterial', 'Ureaplasma', 'Young Adult'] | 24,486,047 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B03.440.190.190.190.750'], ['C01.150.252.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['B03.440.400.425.550.550.474', 'B03.660.075.525.520.400'], ['E05.318.308.985.525.750', 'N01.224.935.597.750... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Stable-isotope selected-ion monitoring quantification of methylmalonic acid in dried filter-paper urine samples. | Urea and creatinine were measured by Kodak Ektachem methods and methylmalonic acid by stable-isotope gas chromatography-mass spectrometry in 24 urine samples from patients with methylmalonic acidaemia. For each sample analyses were performed both directly on the liquid urine and on an aliquot which had been blotted ont... | ['Deuterium', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Metabolism, Inborn Errors', 'Methylmalonic Acid', 'Paper'] | 8,892,020 | [['D01.268.406.500', 'D01.362.340.500', 'D01.496.289'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.320.565', 'C18.452.648'], ['D02.241.081.337.540.500'], ['J01.637.650']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
BIODOSIMETRY AND BIODOSIMETRY NETWORKS FOR MANAGING RADIATION EMERGENCY. | Biological dosimetry enables individual dose reconstruction in the case of unclear or inconsistent radiation exposure situations, especially when a direct measurement of ionizing radiation is not or is no longer possible. To be prepared for large-scale radiological incidents, networking between well-trained laboratorie... | ['Disaster Planning', 'Humans', 'International Agencies', 'Radiation Injuries', 'Radiation Monitoring', 'Radiation Protection', 'Radiation, Ionizing', 'Radioactive Hazard Release', 'Radiometry'] | 30,423,161 | [['N06.230.100.035'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.540.514'], ['C26.733', 'G01.750.748.500', 'N06.850.460.350.850.500', 'N06.850.810.300.360'], ['E05.799.638', 'N06.850.780.375.700', 'N06.850.810.370'], ['N06.850.810.425'], ['G01.750.750'], ['N06.850.135.848'], ['E05.799']] | ['Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of haemodynamic effects of noninvasive ventilation delivered via ResQGARD and CPAP boussignac masks. | UNLABELLED: Noninvasive ventilation (NIV) is a technique of mechanical ventilation which does not require invasive airway management, i.e. intubation or tracheostomy. In emergency medicine Continuous Positive Airway Pressure (CPAP) is used often. A new method of NIV is Impedance Threshold Device (ITD). Breathing throug... | ['Adult', 'Continuous Positive Airway Pressure', 'Female', 'Hemodynamics', 'Humans', 'Hypotension', 'Male', 'Masks', 'Middle Aged', 'Noninvasive Ventilation', 'Reference Values'] | 23,612,619 | [['M01.060.116'], ['E02.041.625.790.259', 'E02.880.820.790.259'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.514'], ['E07.325.877.500', 'E07.700.500', 'E07.858.594.750', 'J01.637.708.560.782'], ['M01.060.116.630'], ['E02.041.625.591', 'E02.880.820.657'], ['E05.978.810']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Endothelin-1 stimulates chloride and potassium secretion in rabbit descending colon. | The vasoactive peptide endothelin-1 (ET-1) which is present in high concentrations in the colon, causes concentration-dependent electrogenic Cl- secretion in rabbit descending colon. This effect is half-maximal at 0.11 mumol/l. Like other secretagogues, ET-1 also stimulates K+ secretion. The secretory effect of ET-1 is... | ['Animals', 'Chlorides', 'Colon', 'Dinoprostone', 'Endothelins', 'In Vitro Techniques', 'Indomethacin', 'Kidney', 'Potassium', 'Rabbits', 'Sodium', 'Sodium-Potassium-Exchanging ATPase', 'Tetrodotoxin'] | 1,326,745 | [['B01.050'], ['D01.210.450.150', 'D01.248.497.158.215'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['D12.644.276.400', 'D12.776.467.400', 'D23.529.400'], ['E05.481'], ['D03.633.100.473.420'], ['A05.810.453'], ['D01.268.549.550', 'D01.268.557.575', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pioglitazone but not glibenclamide improves cardiac expression of heat shock protein 72 and tolerance against ischemia/reperfusion injury in the heredity insulin-resistant rat. | We tested the hypothesis that pioglitazone could restore expression of heat shock protein (HSP)72 in insulin-resistant rat heart. At 12 weeks of age, male Otsuka Long-Evans Tokushima Fatty (OLETF) rats and control (LETO) rats were treated with pioglitazone (10 mg x kg(-1) x day(-1)) or glibenclamide (5 mg x kg(-1) x da... | ['Animals', 'Blotting, Western', 'Diabetes Mellitus, Type 2', 'Fever', 'Glucose Tolerance Test', 'Glyburide', 'HSP72 Heat-Shock Proteins', 'Hypoglycemic Agents', 'Insulin', 'Insulin Resistance', 'Kinetics', 'Male', 'Myocardial Reperfusion Injury', 'Myocardium', 'Phosphatidylinositol 3-Kinases', 'Phosphorylation', 'Piog... | 16,873,703 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C18.452.394.750.149', 'C19.246.300'], ['C23.888.119.344'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['D02.065.950.828.575', 'D02.886.590.795.575'], ['D12.776.580.216.375.202... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Presumptive specific clinical diagnosis of genital ulcer disease (GUD) in a primary health care setting in Nairobi. | Of 22,274 patients 12 years of age or older attending a primary health care clinic in Nairobi, 1076 (4.8%) complained of symptoms suggesting a sexually transmitted disease (STD). Of these, 518 females and 462 males underwent complete clinical evaluation, and 78% had objective microbiologic or clinical evidence of STD, ... | ['Anti-Bacterial Agents', 'Chancroid', 'Diagnosis, Differential', 'Female', 'Haemophilus ducreyi', 'Humans', 'Kenya', 'Male', 'Primary Health Care', 'Prospective Studies', 'Sensitivity and Specificity', 'Treatment Outcome', 'Urban Health'] | 8,799,783 | [['D27.505.954.122.085'], ['C01.150.252.400.700.433.308', 'C01.150.252.734.201', 'C01.221.812.281.201', 'C01.778.281.201', 'C12.294.668.281.201', 'C13.351.500.711.281.201'], ['E01.171'], ['B03.440.450.600.450.125', 'B03.660.250.550.290.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.058.290.120.400'], ['N... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Using the LCP: bereaved relatives' assessments of communication and bereavement. | The Liverpool Care Pathway (LCP) is aimed at improving care and communication in the dying phase. The authors studied whether use of the LCP affects relatives' retrospective evaluation of communication and their level of bereavement. An intervention study was conducted. During the baseline period, usual care was provid... | ['Aged', 'Bereavement', 'Communication', 'Female', 'Health Care Surveys', 'Home Care Services', 'Hospitalization', 'Humans', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Netherlands', 'Nursing Homes', 'Palliative Care', 'Professional-Family Relations', 'Regression Analysis', 'Terminal Care'] | 18,403,578 | [['M01.060.116.100'], ['F01.470.142'], ['F01.145.209', 'L01.143'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['N02.421.143.524', 'N02.421.539.089'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.6... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Complex formation of Sn(II) with glycine: an IR, DTA/TGA and DFT investigation. | The novel Sn(Gly)2?H2O complex compound has been synthesized and characterized by TGA, IR and Raman spectroscopy. Molecular spectroscopy and ab initio simulation have given the evidence of glycine molecule being coordinated to Sn(II) as bidentate chelating ligand by oxygen atom of carboxyl group and nitrogen atom of am... | ['Calorimetry, Differential Scanning', 'Differential Thermal Analysis', 'Glycine', 'Isomerism', 'Models, Molecular', 'Molecular Conformation', 'Quantum Theory', 'Spectrophotometry, Infrared', 'Spectrum Analysis, Raman', 'Thermodynamics', 'Thermogravimetry', 'Tin', 'Vibration'] | 25,123,937 | [['E05.196.131.310', 'E05.196.370.310'], ['E05.196.370'], ['D12.125.481'], ['G02.111.570.685', 'G02.607.445'], ['E05.599.595'], ['G02.111.570.820'], ['H01.671.579.800'], ['E05.196.712.726.676', 'E05.196.867.826.676'], ['E05.196.822.860', 'E05.196.867.890'], ['G01.906'], ['E05.196.904'], ['D01.268.556.875', 'D01.552.544... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Ultrasensitive and simultaneous determination of RNA modified nucleotides by sheathless interfaced capillary electrophoresis-tandem mass spectrometry. | A label-free ultrasensitive determination of eight RNA modified nucleotides simultaneously was first established based on a sheathless capillary electrophoresis-tandem mass spectrometry system. This system performed well using only 500 pg-5 ng practical RNA samples, and a downward trend of most target nucleotides in HC... | ['Electrophoresis, Capillary', 'HCT116 Cells', 'Humans', 'Nucleotides', 'RNA', 'Tandem Mass Spectrometry'] | 31,180,413 | [['E05.196.401.190', 'E05.301.300.190'], ['A11.251.210.190.380', 'A11.251.860.180.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.408.620', 'D13.695'], ['D13.444.735'], ['E05.196.566.880']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human immunodeficiency virus encephalitis in SCID mice. | The human immunodeficiency virus (HIV) is neuroinvasive and commonly causes cognitive and motor deficits during the later stages of viral infection. (referred to as HIV dementia). The mechanism(s) for disease revolves around secretory products produced from immune-activated brain macrophages/microglia. Recently, we dev... | ['AIDS Dementia Complex', 'Animals', 'Astrocytes', 'Brain', 'Disease Models, Animal', 'Encephalitis, Viral', 'Endothelium, Vascular', 'HIV Infections', 'HIV-1', 'Humans', 'Image Processing, Computer-Assisted', 'Injections, Intraventricular', 'Male', 'Mice', 'Mice, SCID', 'Microglia', 'Monocytes', 'Neurons'] | 8,780,406 | [['C01.221.250.875.049', 'C01.221.812.640.400.070', 'C01.778.640.400.070', 'C01.925.782.815.616.400.049', 'C01.925.813.400.070', 'C10.228.140.380.070', 'C20.673.480.070', 'F03.615.400.050'], ['B01.050'], ['A08.637.200', 'A11.650.200'], ['A08.186.211'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C01.207.245.340', ... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Genotypes of glycoprotein B gene among the Indian symptomatic neonates with congenital CMV infection. | BACKGROUND: Cytomegalovirus [CMV] is a causative agent of congenital infection worldwide and often leads to neurological deficits and hearing loss in newborns. Infants born with symptomatic congenital Cytomegalovirus infection [cCMV] are at significant high risk for developing adverse long-term outcomes. In this study,... | ['Base Sequence', 'Cytomegalovirus Infections', 'DNA Primers', 'Female', 'Genotype', 'Humans', 'India', 'Infant, Newborn', 'Male', 'Multiplex Polymerase Chain Reaction', 'Phylogeny', 'Sequence Analysis, DNA', 'Viral Envelope Proteins'] | 31,438,890 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C01.925.256.466.245'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['M01.060.703.520'], ['E05.393.620.500.487'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Immunohistochemical Study on the Expression of G-CSF, G-CSFR, VEGF, VEGFR-1, Foxp3 in First Trimester Trophoblast of Recurrent Pregnancy Loss in Pregnancies Treated with G-CSF and Controls. | BACKGROUND: Recurrent Pregnancy Loss (RPL) is a syndrome recognizing several causes, and in some cases the treatment with Granulocyte Colony Stimulating Factor (G-CSF) may be successful, especially when karyotype of the previous miscarriage showed no embryo chromosomal abnormalities. In order to evaluate the effects of... | ['Abortion, Habitual', 'Adult', 'Decidua', 'Female', 'Forkhead Transcription Factors', 'Gene Expression Regulation', 'Granulocyte Colony-Stimulating Factor', 'Humans', 'Immunohistochemistry', 'Pregnancy', 'Pregnancy Trimester, First', 'Receptors, Granulocyte Colony-Stimulating Factor', 'T-Lymphocytes, Regulatory', 'Tro... | 31,906,232 | [['C13.703.039.089'], ['M01.060.116'], ['A05.360.319.679.490.373', 'A16.710.289'], ['D12.776.260.950.249', 'D12.776.930.977.249'], ['G05.308'], ['D12.644.276.374.410.240.350', 'D12.776.395.240.200', 'D12.776.467.374.410.240.350', 'D23.529.374.410.240.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Association between vascular endothelial growth factor expression and lymph node metastasis in cervical cancer: A meta-analysis. | AIM: The expression of vascular endothelial growth factor (VEGF) by cancer cells has been identified as a factor that is associated with lymph node metastasis (LNM) in some cancers, but an accurate description of the relation between VEGF and LNM in cervical cancer is lacking. We conducted a concurrent meta-analysis to... | ['Female', 'Humans', 'Lymphatic Metastasis', 'Risk Factors', 'Uterine Cervical Neoplasms', 'Vascular Endothelial Growth Factor A'] | 27,334,572 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['C04.588.945.418.948.850', 'C13.351.500.852.593.131', 'C13.351.500.852.762.850', 'C13.35... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Stromal hypocellularity and encapsulation in organ cultures of human prostate: application in epithelial cell isolation. | The primary objective of our study was to obtain pure cultures of prostatic epithelium. The phenomena of encapsulation by epithelial cells and hypocellularity in stroma occurred when explants of human prostatic tissue were maintained in suspension cultures. Hypocellularity progressed with time and was more pronounced i... | ['Aged', 'Cells, Cultured', 'Epithelial Cells', 'Humans', 'Male', 'Organ Culture Techniques', 'Prostate'] | 1,159,919 | [['M01.060.116.100'], ['A11.251'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481.500.484'], ['A05.360.444.575', 'A10.336.707']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of enterolactone on sphingolipid pathway and hepatic insulin resistance development in HepG2 cells. | AIMS: Obesity and type 2 diabetes mellitus, correlate with increased tissue concentration of sphingolipids, which directly interfere with insulin signaling pathway. Phytoestrogens are a group of plant-derived compounds that have been studied in the case of metabolic disorders treatment. Therefore, the aim of this study... | ['4-Butyrolactone', 'Ceramides', 'Hep G2 Cells', 'Humans', 'Insulin', 'Insulin Resistance', 'Lignans', 'Lipid Metabolism', 'Liver', 'Phytoestrogens', 'Signal Transduction', 'Sphingolipids'] | 30,468,835 | [['D02.540.150', 'D03.383.312.150'], ['D02.065.313', 'D09.400.410.420.525.200', 'D10.390.470.675.200', 'D10.570.877.360.612.200'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['C18.452.394.968.500', 'G07.690... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of 'natural' and vaccine-induced haemophilus influenzae type B capsular polysaccharide serum antibodies for 3H1, a V3-23-associated idiotope. | The variable (V-) region repertoire of antibodies (Abs) to Haemophilus influenzae capsular polysaccharide (Hib PS) has been extensively studied in individuals vaccinated against the microbe, but to a lesser extent in subjects who generated such Abs in response to a 'natural' encounter with this microbe or its antigenic... | ['Adult', 'Antibodies, Bacterial', 'Antibodies, Monoclonal', 'Bacterial Capsules', 'Child, Preschool', 'Haemophilus Vaccines', 'Haemophilus influenzae type b', 'Humans', 'Hybridomas', 'Immunoglobulin Idiotypes', 'Immunoglobulin Variable Region', 'Infant', 'Polysaccharides, Bacterial'] | 10,880,838 | [['M01.060.116'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A20.186'], ['M01.060.406.448'], ['D20.215.894.135.450'], ['B03.440.450.600.450.330.150', 'B03.660.250.550.290.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Source-monitoring training facilitates preschoolers' eyewitness memory performance. | Preschool children are more susceptible to misleading postevent information than are older children and adults. One reason for young children's suggestibility is their failure to monitor the source of their memories, as in, for example, discriminating whether an event was seen live versus on television. The authors inv... | ['Child, Preschool', 'Female', 'Humans', 'Male', 'Memory', 'Random Allocation', 'Suggestion', 'Teaching'] | 12,005,385 | [['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['E02.190.525.217.771', 'F04.754.424.771'], ['I02.903']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Four-day infusion of fluorouracil plus vinorelbine as salvage treatment of heavily pretreated metastatic breast cancer. | AIMS: Anthracyclines-taxanes containing regimens are widely used for breast cancer treatment both in neoadjuvant-adjuvant setting and in metastatic disease. Recently high-dose chemotherapy (HDC) with autologous stem cell support has been introduced as adjuvant treatment for high-risk primary breast cancer and for selec... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Breast Neoplasms', 'Female', 'Fluorouracil', 'Humans', 'Infusions, Intravenous', 'Middle Aged', 'Patient Selection', 'Prospective Studies', 'Salvage Therapy', 'Treatment Outcome', 'Vinblastine', 'Vinorelbine'] | 10,966,000 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.180', 'C17.800.090.500'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['M01.060.116.630'], ['E05.581.500.653', 'N04.590.731'], ['E... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cloud point extraction-HPLC method for determination and pharmacokinetic study of flurbiprofen in rat plasma after oral and transdermal administration. | A method based on cloud-point extraction (CPE) was developed for the determination of flurbiprofen (FP) in rat plasma after oral and transdermal administration by high-performance liquid chromatography coupled with UV detection (HPLC-UV). The non-ionic surfactant Genapol X-080 was chosen as the extract solvent. Variabl... | ['Administration, Cutaneous', 'Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Chromatography, High Pressure Liquid', 'Flurbiprofen', 'Rats', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Spectrophotometry, Ultraviolet'] | 18,472,314 | [['E02.319.267.120.060'], ['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['E05.196.181.400.300'], ['D02.241.081.751.161', 'D02.455.426.559.389.185.350'], ['B01.050.150.900.649.313.992.635.505.700'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
MTERF2 contributes to MPP(+)-induced mitochondrial dysfunction and cell damage. | Parkinson's disease (PD) is a common neurodegenerative disorder whose pathogenesis is under intense investigation. Substantial evidence indicates that mitochondrial dysfunction plays a central role in the pathophysiology of PD. Several mitochondrial internal regulating factors act to maintain the mitochondrial function... | ['1-Methyl-4-phenylpyridinium', 'Cell Line', 'DNA-Binding Proteins', 'Humans', 'Mitochondria', 'Mitochondrial Proteins', 'Neurons', 'Parkinsonian Disorders', 'Transcription Factors', 'Up-Regulation'] | 26,826,381 | [['D03.383.725.762.550'], ['A11.251.210'], ['D12.776.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D12.776.575'], ['A08.675', 'A11.671'], ['C10.228.140.079.862', 'C10.228.662.600'], ['D12.776.930'], ['G02.111.905', 'G05.308.850', 'G07.690.773.998']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vitamin K-dependent carboxylase. Possible role for thioredoxin in the reduction of vitamin K metabolites in liver. | In the liver vitamin K epoxide, which is produced during the posttranslational carboxylation of protein-bound glutamic acid residues, is recycled by the action of one or more dithiol-dependent reductases. In vitro synthetic dithiols may serve as a cofactor for these enzymes, but the physiological reductant has not yet ... | ['Animals', 'Bacterial Proteins', 'Carbon-Carbon Ligases', 'Cattle', 'Escherichia coli', 'Ligases', 'Liver', 'Oxidation-Reduction', 'Thioredoxin-Disulfide Reductase', 'Thioredoxins', 'Vitamin K'] | 3,308,517 | [['B01.050'], ['D12.776.097'], ['D08.811.464.257'], ['B01.050.150.900.649.313.500.380.271'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D08.811.464'], ['A03.620'], ['G02.700', 'G03.295.531'], ['D08.811.682.667.750', 'D12.776.331.971'], ['D12.776.915'], ['D02.455.426.559.847.638.721.374', 'D02.455.849.291... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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