Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Microsporidial keratoconjunctivitis after rugby tournament, Singapore. | We investigated an outbreak of 47 probable and 6 confirmed cases of microsporidial keratoconjunctivitis involving participants of an international rugby tournament in Singapore in April 2012.The mode of transmission was eye contact with soil. Vittaforma corneae was identified in 4 of 6 corneal scrapings and in 1 of 12 ... | ['Adolescent', 'Child', 'Disease Outbreaks', 'Female', 'Football', 'Humans', 'Keratoconjunctivitis', 'Male', 'Microsporidia', 'Microsporidiosis', 'Polymerase Chain Reaction', 'Singapore'] | 23,965,938 | [['M01.060.057'], ['M01.060.406'], ['N06.850.290'], ['I03.450.642.845.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.187.183.394', 'C11.204.564.585'], ['B01.300.360'], ['C01.150.703.617'], ['E05.393.620.500'], ['Z01.252.145.774']] | ['Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Severe Burn-Induced Inflammation and Remodeling of Achilles Tendon in a Rat Model. | Severe burn causes systemic inflammation and hypercatabolism, resulting in damage to multiple organs distant to the burn site, including the musculoskeletal system. Bone mass and muscle loss have been reported. However, tendon that connects bone and muscle has not been studied in comparable detail. Here we aimed to cha... | ['Achilles Tendon', 'Animals', 'Burns', 'Collagen Type I', 'Collagen Type III', 'Cytokines', 'Disease Models, Animal', 'Inflammation', 'Male', 'Matrix Metalloproteinase 13', 'Matrix Metalloproteinase 9', 'Rats', 'Rats, Sprague-Dawley', 'Trauma Severity Indices'] | 29,065,066 | [['A02.880.176'], ['B01.050'], ['C26.200'], ['D05.750.078.280.300.100', 'D12.776.860.300.250.300.100'], ['D05.750.078.280.300.300', 'D12.776.860.300.250.300.300'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.550.470'], ['D08.811.277.656.300.480.205.363', '... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Measurement of PIP3 levels reveals an unexpected role for p110â in early adaptive responses to p110á-specific inhibitors in luminal breast cancer. | BYL719, which selectively inhibits the alpha isoform of the phosphatidylinositol 3-kinase (PI3K) catalytic subunit (p110a), is currently in clinical trials for the treatment of solid tumors, especially luminal breast cancers with PIK3CA mutations and/or HER2 amplification. This study reveals that, even among these sens... | ['Animals', 'Antineoplastic Combined Chemotherapy Protocols', 'Breast Neoplasms', 'Cell Line, Tumor', 'Class I Phosphatidylinositol 3-Kinases', 'Female', 'Gene Expression Regulation, Neoplastic', 'Humans', 'MCF-7 Cells', 'Mice', 'Mice, Nude', 'Neoplasm Transplantation', 'Pyrimidinones', 'Receptor, ErbB-2', 'Signal Tran... | 25,544,637 | [['B01.050'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['D08.811.913.696.620.500.100.100', 'D08.811.913.696.620.500.200.100', 'D12.776.476.162'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Wnt9a Promotes Renal Fibrosis by Accelerating Cellular Senescence in Tubular Epithelial Cells. | Cellular senescence is associated with renal disease progression, and accelerated tubular cell senescence promotes the pathogenesis of renal fibrosis. However, the underlying mechanism is unknown. We assessed the potential role of Wnt9a in tubular cell senescence and renal fibrosis. Compared with tubular cells of norma... | ['Animals', 'Cell Line', 'Cellular Senescence', 'Cyclin-Dependent Kinase Inhibitor p16', 'Disease Models, Animal', 'Epithelial Cells', 'Fibroblasts', 'Fibrosis', 'Gene Expression Regulation', 'Genes, p16', 'Humans', 'Kidney', 'Kidney Tubules', 'Male', 'Mice', 'Mice, Inbred C57BL', 'RNA Interference', 'Rats', 'Recombina... | 29,440,280 | [['B01.050'], ['A11.251.210'], ['G04.043'], ['D12.644.360.225.200', 'D12.776.167.187.200', 'D12.776.476.225.200', 'D12.776.624.776.355.200'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A11.436'], ['A11.329.228'], ['C23.550.355'], ['G05.308'], ['G05.360.340.024.340.375.249.375', 'G05.360.340.024.340.415.400.375'],... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The two dimensions of the body representation in women suffering from Anorexia Nervosa. | A core symptom of Anorexia Nervosa (AN) is a severe alteration of body representations. Evidence from somatoperception studies point to a generic disturbances of somatosensory components of body representations. Here we have investigated whether AN patients (N=18) and controls differed in the perception of tactile stim... | ['Adult', 'Anorexia Nervosa', 'Body Image', 'Body Size', 'Female', 'Humans', 'Physical Stimulation', 'Touch', 'Touch Perception', 'Young Adult'] | 26,360,978 | [['M01.060.116'], ['F03.400.125'], ['F01.752.747.792.110', 'F02.463.593.112'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.723'], ['F02.830.816.850', 'G11.561.790.850'], ['F02.463.593.894'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Photoresponsive surface molecularly imprinted polymer on ZnO nanorods for uric acid detection in physiological fluids. | A photoresponsive surface molecularly imprinted polymer for uric acid in physiological fluids was fabricated through a facile and effective method using bio-safe and biocompatible ZnO nanorods as a support. The strategy was carried out by introducing double bonds on the surface of the ZnO nanorods with 3-methacryloxypr... | ['Adsorption', 'Kinetics', 'Methacrylates', 'Molecular Imprinting', 'Nanotubes', 'Polymers', 'Silanes', 'Spectroscopy, Fourier Transform Infrared', 'Uric Acid', 'Water', 'Zinc Oxide'] | 27,207,036 | [['G01.030', 'G02.020'], ['G01.374.661', 'G02.111.490'], ['D02.241.081.069.600'], ['E05.196.655', 'E05.197.453', 'J01.897.836.249.437'], ['J01.637.512.850'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['D01.837.700'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['D03.132.960.877', 'D03.633.100.759.758.824.8... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Experimental infection of non-pregnant and pregnant sheep with Neospora caninum. | In an initial experiment, 21 sheep in groups of five or six were inoculated subcutaneously (sc) with 10(8), 10(6) or 10(4) Neospora caninum tachyzoites (Liverpool isolate), or with control inoculum, and monitored for clinical signs and for "seroconversion". Animals given the two higher doses showed febrile responses an... | ['Animals', 'Antibodies, Protozoan', 'Antigens, Protozoan', 'Body Temperature', 'Brain', 'Female', 'Male', 'Neospora', 'Placenta', 'Pregnancy', 'Protozoan Infections', 'Protozoan Infections, Animal', 'Sheep', 'Time Factors'] | 9,263,840 | [['B01.050'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['D23.050.293'], ['E01.370.600.875.374', 'G07.110'], ['A08.186.211'], ['B01.043.075.189.250.750.550'], ['A16.710'], ['G08.686.784.769'], ['C01.610.752'], ['C01.610.701.688', 'C01.610.752.625', 'C22.674.710'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rural workers' health and productivity: an economic assessment of pesticide use in Minas Gerais, Brazil. | This paper evaluates the economic impact of pesticide intoxication on the health of rural workers in the State of Minas Gerais, Brazil. To estimate the economic impact we considered the purchase cost of pesticides and the treatment costs of rural workers' affected by intoxication. These impacts were compared to the ben... | ['Adolescent', 'Adult', "Agricultural Workers' Diseases", 'Brazil', 'Efficiency', 'Employer Health Costs', 'Female', 'Health Status Indicators', 'Humans', 'Male', 'Middle Aged', 'Occupational Exposure', 'Pesticides', 'Risk Factors', 'Rural Health'] | 14,619,267 | [['M01.060.057'], ['M01.060.116'], ['C24.080'], ['Z01.107.757.176'], ['F02.784.692.351', 'N04.452.209'], ['N03.219.151.400.375', 'N05.300.375.350'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N06.850.... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Activity of glutathione-dependent enzymes in long term diabetes. I. Activity of glutathione S-transferase and glutathione peroxidase in the liver of alloxan induced diabetic rats. | Cytosolic liver glutathione S-transferase (GST) activity was decreased for CDNB and DCNB as substrates in long term alloxan induced diabetes. Similar to cytosolic, microsomal glutathione S-transferase activity was also decreased for CDNB. In contrast, both microsomal and cytosolic GST activities for ETA as well as cyto... | ['Alloxan', 'Animals', 'Cytosol', 'Diabetes Mellitus, Experimental', 'Glutathione', 'Glutathione Peroxidase', 'Glutathione Transferase', 'Liver', 'Male', 'Microsomes, Liver', 'Rats'] | 8,960,250 | [['D03.383.742.698.122'], ['B01.050'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['D12.644.456.448'], ['D08.811.682.732.500'], ['D08.811.913.225.500'], ['A03.620'], ['A11.284.835.540.541'], ['B01.050.150.900.649.313.992.635.505.700'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Our experiences with measurement of new potential biomarkers in the diagnosis of latent forms of myocardial ischemia. | BACKGROUND: The need for a laboratory marker of myocardial ischemia has been alluded to for at least the last decade.AIM: The aim of this study was to evaluate the diagnostic importance of the myosin light chain-1 (MLC-1), clusterin and Reg-Ialpha in patients with suspected myocardial ischemia.METHODS: A group of 176 a... | ['Biomarkers', 'Clusterin', 'Female', 'Humans', 'Lithostathine', 'Male', 'Myocardial Ischemia', 'Myosin Light Chains', 'Sensitivity and Specificity', 'Tomography, Emission-Computed, Single-Photon'] | 17,426,785 | [['D23.101'], ['D12.776.395.207', 'D12.776.580.215'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.503.280.578.500'], ['C14.280.647', 'C14.907.585'], ['D05.750.078.730.475.200', 'D12.776.157.125.475', 'D12.776.210.500.600.200', 'D12.776.220.525.475.200'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Diagnosis and treatment for solitary necrotic nodule of the liver: report of 15 patients]. | OBJECTIVE: To investigate the diagnostic and therapeutic approach of solitary necrotic nodule of the liver (SNNL).METHODS: Fifteen cases were diagnosed as SNNL from June 1999 to December 2005. The clinical characteristics, imaging findings, diagnosis and treatment were analyzed with related literature retrospectively.R... | ['Adult', 'Aged', 'Female', 'Follow-Up Studies', 'Humans', 'Liver', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Necrosis', 'Retrospective Studies'] | 18,241,567 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.060.116.630'], ['C23.550.717'], ['E05.318.372.500.500.500', 'E05.318.37... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of long-term outcome after percutaneous coronary intervention versus coronary artery bypass grafting in patients with unprotected left main coronary artery disease (from the CREDO-Kyoto PCI/CABG Registry Cohort-2). | The long-term outcome of percutaneous coronary intervention (PCI) compared to coronary artery bypass grafting (CABG) for unprotected left main coronary artery disease (ULMCAD) remains to be investigated. We identified 1,005 patients with ULMCAD of 15,939 patients with first coronary revascularization enrolled in the CR... | ['Aged', 'Angioplasty, Balloon, Coronary', 'Coronary Angiography', 'Coronary Artery Bypass', 'Coronary Artery Disease', 'Coronary Vessels', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Japan', 'Male', 'Myocardial Infarction', 'Postoperative Complications', 'Registries', 'Retrospective Studies', 'Risk Factors'... | 22,721,575 | [['M01.060.116.100'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Minimizing Ports During Robotic Partial Nephrectomy. | BACKGROUND AND OBJECTIVE: Robotic upper urinary tract surgery is in most of the cases performed utilizing a standard 5 port configuration. Fewer ports can potentially produce a less invasive operation. Taking in consideration the above we report a novel technique for robot assisted laparoscopic partial nephrectomy util... | ['Adult', 'Aged', 'Blood Loss, Surgical', 'Equipment Design', 'Female', 'Humans', 'Kidney Neoplasms', 'Male', 'Middle Aged', 'Minimally Invasive Surgical Procedures', 'Nephrectomy', 'Operative Time', 'Retrospective Studies', 'Robotic Surgical Procedures'] | 27,403,042 | [['M01.060.116'], ['M01.060.116.100'], ['C23.550.414.300', 'C23.550.505.300'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['M01.060.116.630'], ['E04.502'], ['E04.950.774.435'], ['E04.614.374.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Three-month-old infants show enhanced behavioral and neural sensitivity to fearful faces. | An important feature of the development of emotion recognition in infants is the emergence of a robust attentional bias for fearful faces. There is some debate about when this enhanced sensitivity to fearful expressions develops. The current study explored whether 3-month-olds demonstrate differential behavioral and ne... | ['Emotions', 'Facial Expression', 'Fear', 'Female', 'Humans', 'Infant', 'Male'] | 32,072,932 | [['F01.470'], ['E01.370.600.225', 'F01.145.209.530.385'], ['F01.470.361'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703']] | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fetal middle cerebral artery Doppler indices and clinical application at Korle Bu Teaching Hospital, Accra, Ghana. | OBJECTIVE: To determine normal ranges for various Doppler flow velocity indices of the fetal middle cerebral artery (MCA) and their trends in normal pregnancies at Korle Bu Teaching Hospital, Accra, Ghana.METHODS: A prospective cross-sectional study was conducted at Korle Bu Teaching Hospital in 2015. Included women ha... | ['Adult', 'Blood Flow Velocity', 'Cross-Sectional Studies', 'Female', 'Fetus', 'Gestational Age', 'Ghana', 'Hospitals, Teaching', 'Humans', 'Middle Cerebral Artery', 'Pregnancy', 'Prospective Studies', 'Reference Values', 'Regression Analysis', 'Ultrasonography, Prenatal'] | 27,177,520 | [['M01.060.116'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['A16.378'], ['G07.345.500.325.235.968', 'G08.686.320'], ['Z01.058.290.190.320'], ['N02.278.020.300', 'N02.278.421.639'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Geographicals [Z]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The genomic footprint of climate adaptation in Chironomus riparius. | The gradual heterogeneity of climatic factors poses varying selection pressures across geographic distances that leave signatures of clinal variation in the genome. Separating signatures of clinal adaptation from signatures of other evolutionary forces, such as demographic processes, genetic drift and adaptation, to no... | ['Acclimatization', 'Adaptation, Physiological', 'Animals', 'Chironomidae', 'Climate', 'Climate Change', 'Ecosystem', 'Europe', 'Genetic Drift', 'Genetics, Population', 'Genomics', 'Selection, Genetic'] | 29,473,242 | [['G07.025.133', 'G16.012.500.133'], ['G07.025', 'G16.012.500'], ['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.750'], ['G16.500.275.071', 'N06.230.300.100.250'], ['G16.500.175.374'], ['G16.500.275.157', 'N06.230.124'], ['Z01.542'], ['G05.045.300', 'G05.330.320'], ['H01.158.273.343.335'], ['H01.158.273.180.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
1H NMR techniques in studies of transport of paramagnetic ions in multicellular systems. | Two different pulse sequences used in 1H NMR spectroscopy termed free induction decay amplitude recovery (FIDAR) and spin-echo recovery (SER) were applied to studies of transport of paramagnetic ions in multicellular systems. The molar relaxivity of several paramagnetic species (Fe3+, Co2+, Ni2+, Cu2+, Mn2+, MnEDTA2-, ... | ['Algorithms', 'Biological Transport', 'Cell Membrane', 'Ions', 'Magnetic Resonance Spectroscopy', 'Manganese', 'Plant Cells', 'Water'] | 3,443,285 | [['G17.035', 'L01.224.050'], ['G03.143'], ['A11.284.149'], ['D01.248.497'], ['E05.196.867.519'], ['D01.268.556.484', 'D01.268.956.374', 'D01.552.544.484'], ['A11.750'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Assessment of tissue-engineered islet graft viability by fluorine magnetic resonance spectroscopy. | INTRODUCTION: Despite significant progress in the last decade, islet transplantation remains an experimental therapy for a limited number of patients with type 1 diabetes. Tissue-engineered approaches may provide promising alternatives to the current clinical protocol and would benefit greatly from concurrent developme... | ['Animals', 'Cell Survival', 'Diabetes Mellitus, Type 1', 'Dose-Response Relationship, Drug', 'Fluorine', 'Graft Survival', 'Humans', 'Islets of Langerhans', 'Islets of Langerhans Transplantation', 'Magnetic Resonance Spectroscopy', 'Models, Theoretical', 'Oxygen', 'Oxygen Consumption', 'Partial Pressure', 'Swine', 'Ti... | 22,099,762 | [['B01.050'], ['G04.346'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['G07.690.773.875', 'G07.690.936.500'], ['D01.268.380.300'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.734.414', 'A06.300.414'], ['E02.095.147.500.250', 'E04.270.550', 'E04.936.225.375'], ['E05.196.867.51... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Refinement and psychometric evaluation of the Attitudes Toward Loss of Hearing Questionnaire. | OBJECTIVE: To refine and statistically validate the Attitudes Toward Loss of Hearing Questionnaire (ALHQ) so that it will be appropriate for clinical application and to understand some of the personality attributes underlying attitudes toward hearing loss.DESIGN: An American-English version of an ALHQ, originally desig... | ['Adaptation, Psychological', 'Affect', 'Attitude to Health', 'Audiometry, Pure-Tone', 'Correction of Hearing Impairment', 'Hearing Aids', 'Hearing Disorders', 'Humans', 'Male', 'Personal Satisfaction', 'Psychometrics', 'Speech Perception', 'Surveys and Questionnaires'] | 8,979,038 | [['F01.058'], ['F01.470.047'], ['F01.100.150', 'N05.300.150'], ['E01.370.382.375.060.055'], ['E02.760.169.063.500.200', 'E02.831.200', 'H02.403.680.600.500', 'N02.421.784.377'], ['E07.305.906.500', 'E07.814.458'], ['C09.218.458', 'C10.597.751.418', 'C23.888.592.763.393'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Coblation assisted endoscopic juvenile nasopharyngeal angiofibroma resection. | To provide additional support for the use of coblation in the surgical treatment of juvenile nasopharyngeal angiofibroma (JNA) tumors. Coblation radiofrequency has been recently described in endoscopic sinus surgery for polyp and tumor resection from the sinuses to the skull base. This is a case series from our institu... | ['Ablation Techniques', 'Adolescent', 'Angiofibroma', 'Endoscopy', 'Humans', 'Male', 'Nasopharyngeal Neoplasms', 'Young Adult'] | 22,269,889 | [['E04.014'], ['M01.060.057'], ['C04.557.645.100'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.710.650', 'C07.550.350.650', 'C07.550.745.650', 'C09.647.710.650', 'C09.775.350.650', 'C09.775.549.650'], ['M01.060.116.815']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Transapical mitral valve implantation after unclipping of a MitraClip: a glimpse into the future and treatment considerations in mitral regurgitation. | AIMS: Transcatheter mitral valve implantation (TMVI) is a novel approach that may enable a less invasive effective reduction of mitral regurgitation (MR). A limitation of the MitraClip is that definitive implantation of a clip precludes future therapy with TMVI. The purpose of this paper is to describe contemporary tre... | ['Adult', 'Cardiac Catheterization', 'Echocardiography, Transesophageal', 'Heart Valve Prosthesis Implantation', 'Humans', 'Male', 'Mitral Valve', 'Mitral Valve Insufficiency', 'Patient Selection', 'Prosthesis Design', 'Risk', 'Surgical Instruments', 'Treatment Outcome'] | 27,290,683 | [['M01.060.116'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['E04.100.376.485', 'E04.650.410', 'E04.928.220.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.541.510.507'], ['C14.280.484.461'], ['E05.581.500.653'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of water extract of Hibiscus sabdariffa, Linn (Malvaceae) 'Roselle' on excretion of a diclofenac formulation. | The effect of beverages prepared from the dried calyx of the flowers of Hibiscus sabdariffa on the excretion of diclofenac was investigated using a controlled study in healthy human volunteers. A high pressure liquid chromatographic method was used to analyse the 8 h urine samples collected after the administration of ... | ['Adult', 'Anti-Inflammatory Agents, Non-Steroidal', 'Beverages', 'Cross-Over Studies', 'Diclofenac', 'Female', 'Flowers', 'Food-Drug Interactions', 'Hibiscus', 'Humans', 'Kidney', 'Male', 'Phytotherapy', 'Plant Extracts'] | 17,094,172 | [['M01.060.116'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['G07.203.100', 'J02.200'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D02.241.223.601.210'], ['A18.024.249.500'], ['G07.690.773.968.511'], ['B01.650.940.800.575.912.250.859.821.500.288'], ['B0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Peripheral cholangiocarcinoma and clonorchiasis: CT findings. | Sixteen patients with peripheral cholangiocarcinoma of the liver were examined with computed tomography (CT). None of the 16 patients presented with jaundice or had documented cirrhosis. On scans obtained both before and after the injection of contrast material, the tumors were depicted as low-attenuation masses in all... | ['Adenoma, Bile Duct', 'Animals', 'Bile Duct Neoplasms', 'Bile Ducts, Intrahepatic', 'Clonorchiasis', 'Clonorchis sinensis', 'Female', 'Humans', 'Liver Diseases, Parasitic', 'Male', 'Middle Aged', 'Tomography, X-Ray Computed'] | 2,843,940 | [['C04.557.470.035.085'], ['B01.050'], ['C04.588.274.120.250', 'C06.130.120.120', 'C06.130.320.120', 'C06.301.120.250'], ['A03.159.183.158', 'A03.620.150'], ['C01.610.335.865.148'], ['B01.050.500.500.736.715.520.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.518', 'C06.552.664'], ['M01.060.116.630'],... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Running economy and effort after cycling: Effect of methodological choices. | Prior exercise can negatively affect movement economy of a subsequent task. However, the impact of cycling exercise on the energy cost of subsequent running is difficult to ascertain, possibly because of the use of different methods of calculating economy. We examined the influence of a simulated cycling bout on runnin... | ['Adult', 'Bicycling', 'Energy Metabolism', 'Exercise Test', 'Heart Rate', 'Humans', 'Male', 'Oxygen Consumption', 'Perception', 'Physical Exertion', 'Respiratory Rate', 'Running'] | 32,202,206 | [['M01.060.116'], ['I03.450.642.845.140'], ['G03.295'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.680'], ['F02.463.593'], ['G11.427.683'], ['E01.370.600.875.875', 'G09.772.705.730'], ['G11.427.410.568... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
miR-143 regulates hexokinase 2 expression in cancer cells. | Tumor cells activate pathways that facilitate and stimulate glycolysis even in the presence of adequate levels of oxygen in order to satisfy their continuous need of molecules, such as nucleotides, ATP and fatty acids, necessary to support their rapid proliferation. Accordingly, a variety of human tumors are characteri... | ['Carcinoma, Squamous Cell', 'Cell Line, Tumor', 'Gene Expression Regulation, Neoplastic', 'Head and Neck Neoplasms', 'Hexokinase', 'Humans', 'Keratinocytes', 'MicroRNAs'] | 22,469,988 | [['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.251.210.190', 'A11.251.860.180'], ['G05.308.370'], ['C04.588.443'], ['D08.811.913.696.620.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.409.500', 'A11.436.397'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500']] | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sustained attention and response inhibition in young children at risk for Attention Deficit/Hyperactivity Disorder. | BACKGROUND: Studies of school-aged children, adolescents, and adults with Attention Deficit/Hyperactivity Disorder (ADHD) have variably shown ADHD-related impairment in both inhibitory control and sustained attention. However, few studies have examined ADHD-associated patterns of performance on these tasks among younge... | ['Age Factors', 'Attention', 'Attention Deficit Disorder with Hyperactivity', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Inhibition, Psychological', 'Male', 'Psychometrics', 'Reaction Time', 'Risk Factors', 'Task Performance and Analysis', 'Visual Perception'] | 16,238,669 | [['N05.715.350.075', 'N06.850.490.250'], ['F02.830.104.214'], ['F03.625.094.150'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.405'], ['F04.711.780'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['E05.318.740.60... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
M-wave of proximal retina in cat. | There has been relatively little known about responses from proximal retina in mammals that could contribute to the electroretinogram (ERG). Recently, there has been evidence that the proximal retina is involved in generating the pattern electroretinogram (PERG). In the present work we investigated proximal retinal act... | ['Adaptation, Ocular', 'Animals', 'Cats', 'Electroretinography', 'Light', 'Reaction Time', 'Retina'] | 3,783,227 | [['G14.020'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['E01.370.380.225', 'E01.370.405.270'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['A09.371.729']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Postoperative necrotizing scleritis: a report of four cases. | Postoperative necrotizing scleritis should be considered in cases of persistent localized postoperative inflammation following all forms of surgical trauma. We present the history, clinical findings, and follow-up data of four patients with postoperative necrotizing scleritis. The clinical records of four patients who ... | ['Female', 'Glucocorticoids', 'Humans', 'Immunosuppressive Agents', 'Lens Implantation, Intraocular', 'Male', 'Methotrexate', 'Middle Aged', 'Phacoemulsification', 'Postoperative Complications', 'Prednisolone', 'Retrospective Studies', 'Scleritis', 'Trabeculectomy', 'Vitrectomy'] | 25,371,644 | [['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['E04.540.825.600'], ['D03.633.100.733.631.192.500'], ['M01.060.116.630'], ['E04.540.825.249.704', 'E04.943.875'], ['C23.550.767'], ['D04.210.500.745.432.769.795'], ['E05.318.372.500.500.500', 'E05... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cell proliferation in EMT6 tumours treated with single doses of X-rays or hydroxyurea. II. Computer simulations. | A computer simulation technique was used to analyse data on the proliferation of clonogenic cells in EMT6 tumours treated with 5 mg/mouse of hydroxyurea (HU) or 3.0 Gy (300 rads) X-rays. This simulation technique is able to determine the respective roles of selective killing, blocks in cell progression and recruitment ... | ['Animals', 'Cell Division', 'Clone Cells', 'Computers', 'Hydroxyurea', 'Interphase', 'Mice', 'Mitotic Index', 'Neoplasms, Experimental', 'X-Rays'] | 7,371,067 | [['B01.050'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.353'], ['L01.224.230.260'], ['D02.065.950.395'], ['G04.144.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.225.500.385.500', 'E05.200.500.385.500', 'E05.242.385.500'], ['C04.619', 'E05.598.500.496'], ['G01.35... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Structure/function analysis of the Pantoea stewartii quorum-sensing regulator EsaR as an activator of transcription. | In Pantoea stewartii subsp. stewartii, two regulatory proteins are key to the process of cell-cell communication known as quorum sensing: the LuxI and LuxR homologues EsaI and EsaR. Most LuxR homologues function as activators of transcription in the presence of their cognate acylated homoserine lactone (AHL) signal. Ho... | ['Acyl-Butyrolactones', 'Bacterial Proteins', 'DNA Mutational Analysis', 'DNA-Directed RNA Polymerases', 'Escherichia coli', 'Gene Expression Regulation, Bacterial', 'Mutagenesis, Site-Directed', 'Pantoea', 'Promoter Regions, Genetic', 'Protein Structure, Tertiary', 'Quorum Sensing', 'Recombinant Proteins', 'Sequence H... | 19,820,098 | [['D02.540.232'], ['D12.776.097'], ['E05.393.760.700.300'], ['D08.811.913.696.445.735.270'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.308.300'], ['E05.393.420.601.575'], ['B03.440.450.425.580', 'B03.660.250.150.540'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.6... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
T cells responding to Trypanosoma cruzi detected by membrane TNF-á and CD154 in chagasic patients. | INTRODUCTION: Chagas disease is a parasitic infection whose pathogenesis is related to parasite persistence and a dysfunctional cellular immune response. Variability in cytokine secretion among chronic Trypanosoma cruzi-infected patients might preclude the identification of the pool of antigen specific T cells. The goa... | ['Adult', 'CD4-Positive T-Lymphocytes', 'CD40 Ligand', 'CD8-Positive T-Lymphocytes', 'Cell Membrane', 'Chagas Disease', 'Female', 'Humans', 'Male', 'Middle Aged', 'Trypanosoma cruzi', 'Tumor Necrosis Factor-alpha'] | 28,967,229 | [['M01.060.116'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['D12.644.276.374.750.124', 'D12.776.395.550.185', 'D12.776.467.374.750.124', 'D12.776.543.550.198', 'D23.529.374.750.124'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.49... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antimicrobial resistance in faecal Escherichia coli isolates from farmed red deer and wild small mammals. Detection of a multiresistant E. coli producing extended-spectrum beta-lactamase. | Eighty-nine Escherichia coli isolates recovered from faeces of red deer and small mammals, cohabiting the same area, were analyzed to determine the prevalence and mechanisms of antimicrobial resistance and molecular typing. Antimicrobial resistance was detected in 6.7% of isolates, with resistances to tetracycline and ... | ['Animals', 'Animals, Domestic', 'Animals, Wild', 'Anti-Infective Agents', 'Deer', 'Drug Resistance, Multiple', 'Escherichia coli', 'Escherichia coli Infections', 'Feces', 'Integrons', 'Microbial Sensitivity Tests', 'Molecular Typing', 'Phylogeny', 'Prevalence', 'Rodentia', 'Spain', 'beta-Lactamases'] | 27,012,919 | [['B01.050'], ['B01.050.050.116'], ['B01.050.050.300'], ['D27.505.954.122'], ['B01.050.150.900.649.313.500.380.373'], ['G07.690.773.984.300'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['A12.459'], ['G02.111.570.080.708.330.200.500'], ['E01.370.225.875.595', 'E05.200.875.595',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Control of illegal medroxyprogesterone acetate-application in veal calves by residue analysis in adipose tissue using HPLC/RIA methods. | Procedures for the determination of medroxyprogesterone acetate (MPA) in adipose tissue collected at time of slaughter allowing the control of MPA application to veal calves are described. Screening radioimmunoassays after sample clean-up were sufficient for a first survey of MPA treatments in livestock herds. Validati... | ['Adipose Tissue', 'Animals', 'Cattle', 'Chromatography, High Pressure Liquid', 'Drug and Narcotic Control', 'Female', 'Kinetics', 'Male', 'Medroxyprogesterone', 'Medroxyprogesterone Acetate', 'Radioimmunoassay'] | 2,521,473 | [['A10.165.114'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.181.400.300'], ['I01.880.604.605.250', 'N03.706.615.402.250', 'N04.452.706.310'], ['G01.374.661', 'G02.111.490'], ['D04.210.500.745.745.654.829.395.700'], ['D04.210.500.745.745.654.829.395.700.500'], ['E01.370.384.700', 'E05.478.566.639',... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Novel acidophilic â-galactosidase with high activity at extremely acidic pH region from Teratosphaeria acidotherma AIU BGA-1. | A â-galactosidase exhibiting maximal activity at pH 1.0 was purified from Teratosphaeria acidotherma AIU BGA-1. The enzyme had a molecular mass of 180 kDa and consisted of two heterosubunits of 120 kDa and 66 kDa. The N-terminal amino acid sequence of the large subunit was found to be SPNLQDIVTVDGESY. These physicochem... | ['Amino Acid Sequence', 'Ascomycota', 'Fucose', 'Galactose', 'Hydrogen-Ion Concentration', 'Kinetics', 'Lactase', 'Lactose', 'Molecular Sequence Data', 'Molecular Weight', 'Protein Subunits', 'Substrate Specificity', 'Temperature', 'Whey', 'beta-Galactosidase'] | 25,797,715 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.300.107'], ['D09.254.488'], ['D09.947.875.359.377'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['D08.811.277.450.410.100.500'], ['D09.698.629.305.340', 'D09.947.750.340'], ['L01.453.245.667'], ['G02.494'], ['D12.776.813'], ['G02.111.835'], ['G01.906.595', 'G16.500.2... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Broad-spectrum monoclonal antibody and a sensitive multi-residue indirect competitive enzyme-linked immunosorbent assay for the antibacterial synergists in samples of animal origin. | To monitor the abuse of antibacterial synergists, a hapten, trimethoprim carboxylic derivative (TMPCOOH), was designed by using molecular modelling technology. A broad-spectrum monoclonal antibody (mAb) TMP/2G1 was prepared, for which the IC50 values of trimethoprim, diaveridine, aditoprim, baquiloprim, ormetoprim, and... | ['Animals', 'Anti-Bacterial Agents', 'Antibodies, Monoclonal', 'Enzyme-Linked Immunosorbent Assay', 'Haptens', 'Honey', 'Limit of Detection', 'Meat', 'Milk', 'Pyrimidines', 'Trimethoprim'] | 30,642,487 | [['B01.050'], ['D27.505.954.122.085'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D23.050.550.480'], ['G07.203.300.581', 'J02.500.581'], ['E05.318.74... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Recovery of high purity zinc from filter ash produced during the thermal treatment of waste and inerting of residual materials. | The method described below recovers zinc, a valuable metal that is present in high concentrations in filter ash from the thermal treatment of waste, and returns the filter ash stripped of heavy metals to the combustion process in order to destroy organic substances. On an industrial scale, the heavy metals in the filte... | ['Conservation of Natural Resources', 'Electrolysis', 'Filtration', 'Hydrogen-Ion Concentration', 'Industrial Waste', 'Switzerland', 'Temperature', 'Waste Management', 'Water Pollutants, Chemical', 'Zinc'] | 18,229,749 | [['J01.256', 'N06.230.080'], ['E05.301.250'], ['E05.196.454', 'G01.280', 'G02.263'], ['G02.300'], ['D20.944.420', 'N06.850.460.710.420'], ['Z01.542.883'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['N06.850.780.200.800.800.900', 'N06.850.860.510.900... | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Smooth muscle hyperplasia in an asthmatic patient: do we know it all? | Bronchial smooth muscle hyperplasia is a well-known structural change in asthma. The degree of hyperplasia is related to asthma severity. We report a case of extreme smooth muscle hyperplasia in an asthmatic patient. A 54-year-old female with a diagnosis of analgesic-induced asthma was admitted to our center for nasal ... | ['Asthma', 'Bronchi', 'Female', 'Humans', 'Hyperplasia', 'Middle Aged', 'Muscle, Smooth'] | 20,664,253 | [['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['A04.411.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['M01.060.116.630'], ['A02.633.570', 'A10.690.467']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pyran Rings Containing Polyketides from Penicillium raistrickii. | Five new pyran rings containing polyketides, penicipyrans A-E (1-5), together with the known pestapyrone A (6), were isolated from the saline soil-derived Penicillium raistrickii. Their structures were determined by interpretation of NMR and HRESIMS data. The absolute configurations of compounds 4 and 5 were establishe... | ['Cell Line, Tumor', 'Crystallography, X-Ray', 'Drug Screening Assays, Antitumor', 'HL-60 Cells', 'Humans', 'Isocoumarins', 'K562 Cells', 'Molecular Structure', 'Nuclear Magnetic Resonance, Biomolecular', 'Penicillium', 'Polyketides', 'Pyrans', 'Pyrones', 'X-Ray Diffraction'] | 28,025,533 | [['A11.251.210.190', 'A11.251.860.180'], ['E05.196.309.742.225'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['A11.251.210.190.465', 'A11.251.860.180.465', 'A11.627.340.360.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.663.283.446.800', 'D03.633.100.150.446.800'], ... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Detection of Fukushima Daiichi nuclear power plant accident radioactive traces in Monaco. | Daily air monitoring of radionuclides in the Principality of Monaco (43°73'N, 7°43'E) after the Fukushima Daiichi nuclear power plant accident showed that only Iodine-131 ((131)I) and Caesium isotopes ((134)Cs and (137)Cs) were detected. The peak of (131)I varied and reached its maximum between March 29th and April 5th... | ['Air Pollutants, Radioactive', 'Cesium Radioisotopes', 'Fukushima Nuclear Accident', 'Iodine Radioisotopes', 'Japan', 'Monaco', 'Radiation Monitoring', 'Seawater', 'Water Pollutants, Radioactive'] | 22,381,471 | [['D20.693.101', 'D27.888.284.101.393'], ['D01.268.549.125.500.300', 'D01.268.556.165.500.300', 'D01.496.180.300', 'D01.496.749.190', 'D01.552.528.160.500.300', 'D01.552.544.165.500.300'], ['K01.400.504.984.186', 'N06.850.135.848.750'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['Z01.252.474.46... | ['Chemicals and Drugs [D]', 'Humanities [K]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Characterization of non-adrenergic, non-cholinergic inhibitory responses of the isolated guinea-pig trachea: differences between pre- and post-ganglionic nerve stimulation. | 1 Differences in the mechanism of non-adrenergic, non-cholinergic (NANC) inhibitory responses to preganglionic- and post-ganglionic nerve stimulation were investigated in the guinea-pig isolated trachea. 2 Stimulation of the vagus nerve at frequencies above 4 Hz elicited NANC relaxation of the trachealis muscle. Respon... | ['Animals', 'Autonomic Fibers, Postganglionic', 'Autonomic Fibers, Preganglionic', 'Autonomic Nervous System', 'Electric Stimulation', 'Enzyme Inhibitors', 'Female', 'Guinea Pigs', 'In Vitro Techniques', 'Male', 'Muscle, Smooth', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type III', 'Nitroarginine', 'Synapses', 'T... | 10,510,458 | [['B01.050'], ['A08.675.542.100', 'A08.800.050.050.050', 'A08.800.800.060.050', 'A11.671.501.100'], ['A08.675.127.500.060', 'A08.675.542.234.060', 'A08.800.050.050.060', 'A08.800.800.060.060', 'A11.671.188.500.060', 'A11.671.501.234.060'], ['A08.800.050'], ['E05.723.402'], ['D27.505.519.389'], ['B01.050.150.900.649.313... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human pituitary growth hormone (hGH) and Creutzfeldt-Jakob disease: results of an epidemiological survey in France, 1986. | An epidemiological inquiry has been done in France after the notification in the USA and England of four cases of Creutzfeldt-Jakob disease in patients previously treated with hGH. Between 1959, when hGH treatment in France was started, and August 1985, the date the survey began, 1698 patients were registered for treat... | ['Adolescent', 'Child', 'Child, Preschool', 'Creutzfeldt-Jakob Syndrome', 'Drug Contamination', 'Epidemiologic Methods', 'Female', 'France', 'Growth Hormone', 'Humans', 'Infant', 'Male', 'Virus Diseases'] | 3,042,652 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['C01.207.800.230', 'C10.228.140.380.165', 'C10.228.228.800.230', 'F03.615.400.300'], ['N06.850.360'], ['E05.318', 'N06.850.520'], ['Z01.542.286'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.7... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Bilateral ocular scrofuloderma with orbital tuberculosis. | Ocular scrofuloderma with orbital tuberculosis is a rarely described presentation of childhood tuberculosis. Bilateral involvement has not been reported earlier in the medical literature. Here is reported a 3-year-old boy who presented with bilateral infraorbital swellings of tubercular etiology. Computed tomography (C... | ['Child, Preschool', 'Humans', 'Male', 'Mycobacterium tuberculosis', 'Orbital Diseases', 'Tuberculosis, Cutaneous', 'Tuberculosis, Ocular'] | 16,816,501 | [['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['C11.675'], ['C01.150.252.410.040.552.846.588', 'C01.150.252.819.820', 'C01.800.720.820', 'C17.800.838.765.820'], ['C01.150.252.289.800', 'C01.375.354.800', 'C11.294.354.800']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Postsplinting x-rays of nondisplaced hand, wrist, ankle, and foot fractures are unnecessary. | BACKGROUND: Acute nondisplaced fractures (NDFs) are common in the emergency department (ED), and providers often obtain postsplinting x-rays to identify displacement that potentially occurs during the splinting process. Our objectives are to (1) determine how often x-rays are obtained after splinting of NDFs, (2) ident... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Ankle Injuries', 'Child', 'Child, Preschool', 'Female', 'Foot Injuries', 'Fracture Fixation, Internal', 'Fractures, Bone', 'Hand Injuries', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Postoperative Period', 'Radiography', 'Retrospective Studies', 'Splints', 'Wrist I... | 27,236,855 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C26.558.100'], ['M01.060.406'], ['M01.060.406.448'], ['C26.558.300'], ['E04.555.300.300'], ['C26.404'], ['C26.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['E04.614.750', 'N02.421.585.753.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Experimental evaluation of anthracycline analogs. | This review summarizes the preclinical tests conducted to date for experimental evaluation of new anthracycline analogs. Most of the data are derived from the experience at the Istituto Nazionale Tumori, Milan, Italy, at the National Cancer Institute, Bethesda, Md, and at the Farmitalia Research Laboratories, Nerviano,... | ['Animals', 'Antibiotics, Antineoplastic', 'Daunorubicin', 'Disease Models, Animal', 'Doxorubicin', 'Drug Administration Schedule', 'Drug Evaluation, Preclinical', 'Glycosides', 'HeLa Cells', 'Heart', 'Leukemia L1210', 'Leukemia, Experimental', 'Mice', 'Naphthacenes', 'Neoplasms, Experimental', 'Sarcoma, Experimental'] | 455,325 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Monoclonal Antibody Against N Terminal 439-451 Epitopes of Anti-Mullerian Hormone and Its Properties]. | Objective: To prepare the specific monoclonal antibody against the N-terminal specific epitope peptide of anti-mullerian hormone (AMH) and to identify its specificity.Methods: Using bioinformatics analysis software to predict the specific peptide fragment of AMH. Then synthesized four antigenic epitope peptide segments... | ['Animals', 'Anti-Mullerian Hormone', 'Antibodies, Monoclonal', 'Computational Biology', 'Epitopes', 'Humans', 'Hybridomas', 'Mice', 'Mice, Inbred BALB C'] | 32,691,556 | [['B01.050'], ['D06.472.334.984.500', 'D09.400.430.625', 'D12.776.395.089'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['H01.158.273.180', 'L01.313.124'], ['D23.050.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.353.485', 'A11.251.600.485'], ['B01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Identification of a common 6-pyruvoyl-tetrahydropterin synthase mutation at codon 87 in Chinese phenylketonuria caused by tetrahydrobiopterin synthesis deficiency. | Deficiency in 6-pyruvoyl-tetrahydropterin synthase (PTPS) activity is the major cause of tetrahydrobiopterin (BH4)-deficient phenylketonuria. Two single base alterations of PTPS cDNA, a C-to-T transition at nucleotide 259 and a novel A-to-G transition at nucleotide 155 (according to cDNA sequence), were identified in t... | ['Adult', 'Alcohol Oxidoreductases', 'Biopterin', 'Child', 'Child, Preschool', 'China', 'Codon', 'DNA, Complementary', 'Humans', 'Infant', 'Male', 'Mutation', 'Phenylketonurias', 'Phosphorus-Oxygen Lyases'] | 8,707,300 | [['M01.060.116'], ['D08.811.682.047'], ['D03.633.100.733.631.202', 'D08.211.090'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.252.474.164'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['B01.050.150.900.649.31... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Stimulation of bronchoalveolar lavage (BAL) and blood lymphocytes by Kveim antigen, tuberculin and concanavalin A in sarcoidosis. | BAL and blood mononuclear cells and their reactivity to Kveim antigen, tuberculin and concanavalin A (Con A) were studied in nine patients with different clinical stages of sarcoidosis. After separation by plastic adherence, non-adherent cells (mainly lymphocytes) were admixed with 10% autologous adherent cells (monocy... | ['Adult', 'Bronchoalveolar Lavage Fluid', 'Concanavalin A', 'Female', 'Humans', 'Kveim Test', 'Leukocyte Count', 'Lung Diseases', 'Lymphocyte Activation', 'Lymphocytes', 'Male', 'Middle Aged', 'Sarcoidosis', 'Skin Tests', 'Stimulation, Chemical', 'Tuberculin'] | 3,256,351 | [['M01.060.116'], ['E05.927.100.500'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.871.300.540', 'E05.200.812.871.300.540', 'E05.478.594.890.300.540'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.62... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Annexin-A1 enhances breast cancer growth and migration by promoting alternative macrophage polarization in the tumour microenvironment. | Macrophages are potent immune cells with well-established roles in the response to stress, injury, infection and inflammation. The classically activated macrophages (M1) are induced by lipopolysaccharide (LPS) and express a wide range of pro-inflammatory genes. M2 macrophages are induced by T helper type 2 cytokines su... | ['Animals', 'Annexin A1', 'Cell Movement', 'Cell Proliferation', 'Extracellular Signal-Regulated MAP Kinases', 'Female', 'Macrophages', 'Mammary Neoplasms, Animal', 'Mice', 'NF-kappa B', 'Receptors, Formyl Peptide', 'Signal Transduction', 'Tumor Cells, Cultured', 'Tumor Microenvironment'] | 29,263,330 | [['B01.050'], ['D12.776.157.125.050.050'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.169'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['C04.588.531', 'C22.520'], ['B01... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In Silico Prediction of Cytochrome P450-Drug Interaction: QSARs for CYP3A4 and CYP2C9. | Cytochromes P450 (CYP) are the main actors in the oxidation of xenobiotics and play a crucial role in drug safety, persistence, bioactivation, and drug-drug/food-drug interaction. This work aims to develop Quantitative Structure-Activity Relationship (QSAR) models to predict the drug interaction with two of the most im... | ['Animals', 'Computer Simulation', 'Cytochrome P-450 CYP2C9', 'Cytochrome P-450 CYP2C9 Inhibitors', 'Cytochrome P-450 CYP3A', 'Cytochrome P-450 CYP3A Inhibitors', 'Humans', 'Protein Binding', 'Quantitative Structure-Activity Relationship'] | 27,294,921 | [['B01.050'], ['L01.224.160'], ['D08.244.453.491.500.500', 'D08.811.682.690.708.170.450.500.500', 'D12.776.422.220.453.491.500.500'], ['D27.505.389.500.315', 'D27.505.519.389.335.329'], ['D08.244.453.860.500', 'D08.811.682.662.582.353', 'D08.811.682.690.708.170.495.500', 'D12.776.422.220.453.860.500'], ['D27.505.389.50... | ['Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Routing Physarum with repellents. | Plasmodium of Physarum polycephalum is a single cell with many nuclei. Plasmodium is an easy-to-experiment-with biological substrate, a multi-functional bio-material used to implement novel and future computing architectures. The plasmodium exhibits typical features of excitable chemical systems and capable for distrib... | ['Antiprotozoal Agents', 'Computers, Molecular', 'Diffusion', 'Physarum polycephalum', 'Sodium Chloride'] | 20,401,510 | [['D27.505.954.122.250.100'], ['L01.224.230.260.315', 'L01.224.300'], ['G01.202', 'G02.196'], ['B01.046.550.550.600.700.550'], ['D01.210.450.150.875', 'D01.857.650']] | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Dietary amino acid profiles and growth performance in juvenile kuruma prawn Marsupenaeus japonicus. | To assess the reference dietary amino acid profiles for juvenile kuruma prawn Marsupenaeus japonicus a feeding trial was conducted using six semi-purified diets containing casein-gelatin and pre-coated supplemental crystalline amino acids (CAA) and a control diet containing intact protein (casein-gelatin). Pre-coated C... | ['Amino Acids', 'Animal Feed', 'Animals', 'Body Composition', 'Body Weight', 'Decapoda', 'Dietary Proteins', 'Growth', 'Nutritional Requirements'] | 12,431,396 | [['D12.125'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['B01.050.500.131.365.190'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.345... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Treatment and justice. | Support for the belief that criminal behaviour was amenable to treatment served different purposes: for developing psychiatry it offered a module of power to be exploited whereas for the State it was a convenient disguise for the infliction of pain which was the real intention of punishment. Having served its purpose t... | ['Crime', 'Criminal Law', 'Humans', 'Jurisprudence', 'Mental Disorders', 'Patient Compliance', 'Punishment', 'Social Adjustment', 'United Kingdom'] | 4,016,399 | [['I01.198.240', 'I01.880.735.191'], ['I01.198.290', 'I01.880.604.583.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.583', 'N03.706.535'], ['F03'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ['F02.463.425.770.571', 'I01.880.630.716'], ['F01.145.813.621'], [... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Chlamydia pneumoniae multiply in neutrophil granulocytes and delay their spontaneous apoptosis. | The obligate intracellular bacterial pathogen Chlamydia pneumoniae (Cp) is responsible for a range of human diseases, including acute respiratory infection. Although experimental intratracheal infection with Cp results in a massive recruitment of neutrophil granulocytes (polymorphonuclear neutrophils (PMN)), the role o... | ['Adult', 'Apoptosis', 'Caspase 3', 'Caspase Inhibitors', 'Caspases', 'Cell Communication', 'Cell Survival', 'Cell-Free System', 'Cells, Cultured', 'Chlamydophila pneumoniae', 'Coculture Techniques', 'Down-Regulation', 'Enzyme Precursors', 'Hot Temperature', 'Humans', 'Interleukin-8', 'Intracellular Fluid', 'Lipopolysa... | 14,734,760 | [['M01.060.116'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D27.505.519.389.745.325.500'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Microstructure of Pharmaceutical Semicrystalline Dispersions: The Significance of Polymer Conformation. | The microstructure of pharmaceutical semicrystalline solid dispersions has attracted extensive attention due to its complexity that might result in the diversity in physical stability, dissolution behavior, and pharmaceutical performance of the systems. Numerous factors have been reported that dictate the microstructur... | ['Calorimetry, Differential Scanning', 'Chemistry, Pharmaceutical', 'Drug Liberation', 'Drug Stability', 'Molecular Conformation', 'Molecular Weight', 'Polymers', 'X-Ray Diffraction'] | 29,320,195 | [['E05.196.131.310', 'E05.196.370.310'], ['H01.158.703.007', 'H01.181.466'], ['G02.211', 'G03.787.321', 'G07.690.725.321'], ['E05.916.330'], ['G02.111.570.820'], ['G02.494'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['E05.196.309.742', 'E05.196.822.950', 'G01.867.950', 'G02.965']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[Changes in porphyrin metabolism of mice given beryllium and/or zinc]. | Beryllium chloride and/or zinc chloride were intraperitoneally injected into mice. The amount of beryllium (Be) injected corresponded to 1/10th of the LD50 dose intravenously administered. The amount of zinc (Zn) injected was the same as Be. The changes in porphyrin metabolism of the mice were studied. Delta-aminolevul... | ['Animals', 'Beryllium', 'Chlorides', 'Hydroxymethylbilane Synthase', 'Liver', 'Male', 'Mice', 'Mice, Inbred ICR', 'Porphobilinogen Synthase', 'Porphyrins', 'Spleen', 'Zinc Compounds'] | 9,211,591 | [['B01.050'], ['D01.268.552.075', 'D01.268.557.080', 'D01.552.547.080'], ['D01.210.450.150', 'D01.248.497.158.215'], ['D08.811.913.225.575'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.510', 'B01.050.150.900.649.313.992.635.505.500.400.510'], ['D08.811.520.241.300.550'], ['D03.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Change and Innovation in the Funeral Industry. | The "modern" or traditional funeral, as it is known in the funeral industry today, that includes embalming, casket, service, and burial in a cemetery, emerged as a result of four forces in American society: the Industrial Revolution, the Civil War, the emergence of a genteel code of conduct as a result of increased wea... | ['Attitude to Death', 'Funeral Rites', 'History, 17th Century', 'History, 18th Century', 'History, 19th Century', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Organizational Innovation', 'United States'] | 28,395,641 | [['F01.100.125', 'N05.300.125'], ['I01.076.201.450.550'], ['K01.400.504.750'], ['K01.400.504.875'], ['K01.400.504.937'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.610'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
What predicts depression in cardiac patients: sociodemographic factors, disease severity or theoretical vulnerabilities? | Depression is associated with increased cardiovascular risk in acute coronary syndrome (ACS) patients, but some argue that elevated depression is actually a marker of cardiovascular disease severity. Therefore, disease indices should better predict depression than established theoretical causes of depression (interpers... | ['Acute Coronary Syndrome', 'Adaptation, Psychological', 'Aged', 'Angina, Unstable', 'Cross-Sectional Studies', 'Culture', 'Depressive Disorder', 'Disability Evaluation', 'Female', 'Humans', 'Internal-External Control', 'Life Change Events', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Personality Inventory', 'Psyc... | 21,038,172 | [['C14.280.647.124', 'C14.907.585.124'], ['F01.058'], ['M01.060.116.100'], ['C14.280.647.187.150', 'C14.907.585.187.150', 'C23.888.592.612.233.500.150'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.076.201.450', 'I01.880.853.100'], ['F03.600.300'], ['E01.370.400'], ['B01.050.150... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Sex-sorted bovine spermatozoa and DNA damage: I. Static features. | This study examined the static response of Spermatozoa DNA Fragmentation (SDF) after sex selection in bulls using a MoFlo(®) SX (Beckman Coulter, Miami FL) spermatozoa sorter to produce three different subpopulations: 1) Spermatozoa bearing X- chromosomes with a purity of 95%, 2) Spermatozoa bearing Y-chromosomes with ... | ['Animals', 'Cattle', 'Cell Separation', 'DNA Damage', 'DNA Fragmentation', 'Flow Cytometry', 'Male', 'Quality Control', 'Semen Analysis', 'Sex Preselection', 'Spermatozoa', 'Static Electricity'] | 20,932,559 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['G05.200'], ['G05.200.230'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['J01... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Indirect adaptive soft computing based wavelet-embedded control paradigms for WT/PV/SOFC in a grid/charging station connected hybrid power system. | This paper focuses on the indirect adaptive tracking control of renewable energy sources in a grid-connected hybrid power system. The renewable energy systems have low efficiency and intermittent nature due to unpredictable meteorological conditions. The domestic load and the conventional charging stations behave in an... | ['Algorithms', 'Electric Power Supplies', 'Electricity', 'Models, Theoretical', 'Oxides', 'Wind'] | 28,877,191 | [['G17.035', 'L01.224.050'], ['E07.305.124'], ['G01.358.500.249'], ['E05.599'], ['D01.248.497.158.685', 'D01.650.550'], ['G16.500.175.249.200', 'G16.500.275.063.725.154.200', 'G16.500.750.775.780', 'N06.230.132.644.875', 'N06.230.300.100.150.185.200', 'N06.230.300.100.725.780']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Mortality and complications in very old patients (90+) admitted to departments of internal medicine in Spain. | SUMMARY: Patients over 90 years of age (the "very elderly") account for an increasing number of admissions to departments of internal medicine (IM). The aim of this study was to analyse the demographic data, hospitalization characteristics, medical complications, and predictors of mortality in patients over 90 admitted... | ['Age Distribution', 'Aged, 80 and over', 'Cohort Studies', 'Communicable Diseases', 'Cross Infection', 'Dementia', 'Female', 'Hip Fractures', 'Hospital Departments', 'Hospital Mortality', 'Humans', 'Inpatients', 'Internal Medicine', 'Male', 'Neoplasms', 'Odds Ratio', 'Patient Admission', 'Patient Discharge', 'Pressure... | 21,238,893 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C01.221', 'C23.550.291.531'], ['C01.248', 'C23.550.291.875.500'], ['C10.228.140.380', 'F03.615.400'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], [... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Geographica... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
HLA-DP4, the most frequent HLA II molecule, defines a new supertype of peptide-binding specificity. | Among HLA-DP specificities, HLA-DP4 specificity involves at least two molecules, HLA-DPA1*0103/DPB1*0401 (DP401) and HLA-DPA1*0103/DPB1*0402 (DP402), which differ from each other by only three residues. Together, they are present worldwide at an allelic frequency of 20-60% and are the most abundant human HLA II alleles... | ['Amino Acid Motifs', 'Amino Acid Sequence', 'Amino Acid Substitution', 'Cell Line', 'Epitopes', 'Gene Frequency', 'HLA-DP Antigens', 'HLA-DP beta-Chains', 'Histocompatibility Testing', 'Humans', 'Models, Molecular', 'Molecular Sequence Data', 'Mutation', 'Peptides', 'Polymorphism, Genetic', 'Protein Binding', 'Sequenc... | 12,471,126 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['A11.251.210'], ['D23.050.550'], ['G05.330'], ['D12.776.395.550.509.400.420', 'D12.776.543.550.440.400.420', 'D23.050.301.500.400.400.420', 'D23.050.301.500.450.400.420',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Preterm delivery risk in migrants in Italy: an observational prospective study. | BACKGROUND: Various studies have ascertained different birth outcomes between resident and migrant populations in western countries. Considering preterm delivery (<37 complete weeks of gestation) as a perinatal risk condition, we assessed its rate in migrant and native Italian women who delivered in the main public hos... | ['Adult', 'Africa', 'Asia', 'Cohort Studies', 'Confidence Intervals', 'Emigration and Immigration', 'Europe', 'Female', 'Health Services Accessibility', 'Humans', 'Italy', 'Life Style', 'Obstetric Labor, Premature', 'Odds Ratio', 'Pregnancy', 'Pregnancy Outcome', 'Prenatal Care', 'Prospective Studies', 'Regression Anal... | 18,666,924 | [['M01.060.116'], ['Z01.058'], ['Z01.252'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.500'], ['Z01.542'], ['N04.590.374.350', 'N05.300.430'], ['... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Development of interferon-specific monoclonal antibody for in vitro interferon assays. | In this study, monoclonal antibodies (MABs) to human interferon alpha (HuIFN alpha) were evaluated for their suitability for the quantification of different HuIFN alpha preparations by conventional immunoassay methods. The results obtained using four different MABs were compared and suggest that whilst immunoassays can... | ['Antibodies, Monoclonal', 'Biological Assay', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Immunoassay', 'Interferon Type I'] | 3,792,649 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['E05.091'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['D12.644.276... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assignment of two loci for autosomal dominant adolescent idiopathic scoliosis to chromosomes 9q31.2-q34.2 and 17q25.3-qtel. | BACKGROUND: Adolescent idiopathic scoliosis (AIS) is the most common form of spinal deformity, affecting up to 4% of children worldwide. Familial inheritance of AIS is now recognised and several potential candidate loci have been found.METHODS: We studied 25 multi-generation AIS families of British descent with at leas... | ['Adolescent', 'Chromosome Mapping', 'Chromosomes, Human, Pair 17', 'Chromosomes, Human, Pair 9', 'Female', 'Genes, Dominant', 'Genotype', 'Humans', 'Lod Score', 'Male', 'Phenotype', 'Scoliosis'] | 17,932,119 | [['M01.060.057'], ['E05.393.183'], ['A11.284.187.520.300.415.425', 'G05.360.162.520.300.415.425'], ['A11.284.187.520.300.325.345', 'G05.360.162.520.300.325.345'], ['G05.360.340.024.340.240', 'G05.420.320'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.348.750'], ['G05.695'], ['C05.116.900.800.875... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Roles of mechanistic target of rapamycin and transforming growth factor-â signaling in the molting gland (Y-organ) of the blackback land crab, Gecarcinus lateralis. | Molting in decapod crustaceans is controlled by molt-inhibiting hormone (MIH), an eyestalk neuropeptide that suppresses production of ecdysteroids by a pair of molting glands (Y-organs or YOs). Eyestalk ablation (ESA) activates the YOs, which hypertrophy and increase ecdysteroid secretion. At mid premolt, which occurs ... | ['Animals', 'Benzamides', 'Brachyura', 'Dioxoles', 'Ecdysteroids', 'Gene Expression Regulation', 'Hemolymph', 'Molting', 'Signal Transduction', 'Sirolimus', 'TOR Serine-Threonine Kinases', 'Transforming Growth Factor beta'] | 27,040,186 | [['B01.050'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['B01.050.500.131.365.190.110'], ['D03.383.246'], ['D04.210.500.247.222.265.165', 'D04.210.500.247.808.756.143', 'D06.472.445.573.271', 'D10.570.938.795.143', 'D23.704.500.143'], ['G05.308'], ['A13.453'], ['G07.345.500.550.750'], ['G02... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Indigenous bacteria may interfere with the biocontrol of plant diseases. | Prodigiosin is a reddish antibiotic pigment that plays an important role in the biocontrol of plant diseases by the bacterium Serratia marcescens. However, its activity is unstable under agricultural conditions; further, it can be degraded by various environmental factors. To examine the effect of epiphytic microbes on... | ['Bacteria', 'Bacterial Physiological Phenomena', 'Caulobacter', 'Cyclamen', 'DNA Primers', 'DNA, Bacterial', 'Plant Diseases', 'Plants', 'Prodigiosin', 'Pseudomonas', 'Rhizobium'] | 19,288,072 | [['B03'], ['G06.099'], ['B03.440.400.280', 'B03.440.400.425.288.100', 'B03.660.050.090.100'], ['B01.650.940.800.575.912.250.341.984.549'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.212'], ['G15.610'], ['B01.650'], ['D03.383.129.578.748', 'D23.767.778'], ['B03.440.400.425.625.625', 'B03.6... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microcetus lappus gen. nov., sp. nov.: new species of ciliated protozoon from the bovine rumen. | A new species of small, ciliated protozoon, Microcetus lappus gen. nov., sp. nov., from the rumen of Norwegian Red cattle is described. M. lappus possesses a novel cytopharyngeal apparatus of two rod-shaped structures, one situated on the dorsal side of the buccal cavity and one on the ventral side, suggesting that it ... | ['Animals', 'Cattle', 'Ciliophora', 'Microscopy, Electron, Scanning', 'Rumen'] | 3,094,449 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['B01.043.185'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['A13.869.804']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vitro susceptibilities of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum to sparfloxacin and PD 127391. | The in vitro activities of two investigational quinolones, sparfloxacin (previously designated AT 4140) and PD 127391, were determined for 30 strains each of Mycoplasma pneumoniae, Mycoplasma hominis, and Ureaplasma urealyticum and compared with those of ciprofloxacin, tetracycline, clindamycin, and erythromycin. Eryth... | ['Anti-Infective Agents', 'Ciprofloxacin', 'Clindamycin', 'Culture Media', 'Erythromycin', 'Fluoroquinolones', 'Hydrogen-Ion Concentration', 'Microbial Sensitivity Tests', 'Mycoplasma', 'Mycoplasma pneumoniae', 'Tetracycline', 'Ureaplasma'] | 1,929,260 | [['D27.505.954.122'], ['D03.633.100.810.835.322.186'], ['D03.383.773.532.500.125', 'D09.408.471.500.125'], ['D27.720.470.305', 'E07.206'], ['D02.540.576.500.992'], ['D03.633.100.810.835.322'], ['G02.300'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['B03.440.860.580.553.553'], ['B03.440.860.580.553.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Implementing the birth dose of hepatitis B vaccine in rural Indonesia. | Reaching mothers and their newborn infants around the time of birth with adequate health services has long been a difficult problem in developing countries. In parallel, similar problems have arisen in attempting to deliver hepatitis B (HepB) vaccine to infants born at home in many countries where mother-to-infant tran... | ['Female', 'Hepatitis B', 'Hepatitis B Vaccines', 'Humans', 'Immunization Programs', 'Indonesia', 'Infant, Newborn', 'Infectious Disease Transmission, Vertical', 'Pregnancy'] | 17,604,881 | [['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['D20.215.894.899.955.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.726.608'], ['Z01.252.145.380', 'Z01.639.580'], ['M01.060.703.520'], ['N06.850.335.875'], ['G08.686.784.769']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Identification of metallic-smelling 1-octen-3-one and 1-nonen-3-one from solutions of ferrous sulfate. | Taste threshold tests of ferrous sulfate (FeSO4) solutions have been confounded by the presence of putative odorants. To detect the presence of odorants released from these solutions solid-phase microextraction (SPME) was used to collect volatiles in the headspace above FeSO4 solutions. Gas chromatography-olfactometry ... | ['Chromatography, Gas', 'Ferrous Compounds', 'Humans', 'Ketones', 'Odorants', 'Smell', 'Solutions'] | 16,218,683 | [['E05.196.181.349'], ['D01.490.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.522'], ['G16.500.275.640', 'N06.230.480'], ['F02.830.816.643', 'G11.561.790.643'], ['D26.776']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Correlation dimension maps of EEG from epileptic absences. | PURPOSE: The understanding of brain activity, and in particular events such as epileptic seizures, lies on the characterisation of the dynamics of the neural networks. The theory of non-linear dynamics provides signal analysis techniques which may give new information on the behaviour of such networks.METHODS: We calcu... | ['Adolescent', 'Anticonvulsants', 'Brain Mapping', 'Child', 'Drug Resistance', 'Electroencephalography', 'Epilepsy, Absence', 'Female', 'Humans', 'Hyperventilation', 'Male', 'Photic Stimulation', 'Valproic Acid'] | 10,217,444 | [['M01.060.057'], ['D27.505.954.427.080'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['M01.060.406'], ['G07.690.773.984'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.375.260', 'C10.228.140.490.493.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.618.501', 'C2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Characterization of the porcine peptidylarginine deiminase type VI gene (PADI6) promoter: Sp1 regulates basal transcription of the porcine PADI6. | It is a general consensus that oocyte quality is the key to embryo survival in pig reproduction. Thus, study on regulation of the ovary-associated gene is of great significance in pig breeding. Peptidylarginine deiminases (PADs) are a family of enzymes which catalyze the conversion of arginine to citrulline in proteins... | ['Animals', 'CHO Cells', 'Cricetulus', 'DNA Mutational Analysis', 'Female', 'Gene Expression Regulation', 'HeLa Cells', 'Humans', 'Hydrolases', 'Plicamycin', 'Promoter Regions, Genetic', 'Protein Binding', 'Sp1 Transcription Factor', 'Swine', 'Transcription, Genetic'] | 26,403,316 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['E05.393.760.700.300'], ['G05.308'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277'], ['D02.455.426.559.847.562.050.650', 'D04.615.562.050.6... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increase in differentiated type of T lineage cells in the myasthenic thymus: two-color fluorocytometric analysis. | We made use of two-color flow cytometry to examine thymic lymphoid cells from patients with myasthenia gravis. The CD4+CD8- cells and the CD4-CD8+ cells were significantly increased in the thymus from the patients, compared with findings in the control samples. Conversely, the CD4+CD8+ cells were significantly decrease... | ['Adolescent', 'Adult', 'Antigens, Differentiation, T-Lymphocyte', 'CD4 Antigens', 'CD8 Antigens', 'Female', 'Flow Cytometry', 'Humans', 'Male', 'Middle Aged', 'Myasthenia Gravis', 'T-Lymphocytes', 'Thymus Gland'] | 2,113,791 | [['M01.060.057'], ['M01.060.116'], ['D23.050.301.264.894', 'D23.101.100.894'], ['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.301.264.894.100', 'D23.101.100.894.100'], ['D23.050.301.264.894.108', 'D23.101.100.894.108'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reconceptualizing successful aging among black women and the relevance of the strong black woman archetype. | Although there are multiple pathways to successful aging, little is known of what it means to age successfully among black women. There is a growing body of literature suggesting that black women experience a number of social challenges (sexism and racism) that may present as barriers to aging successfully. Applying as... | ['Adaptation, Psychological', 'Adult', 'African Americans', 'African Continental Ancestry Group', 'Aging', 'Female', 'Geriatrics', 'Health Status', 'Humans', 'Mental Disorders', 'Mental Health', 'Quality of Life', 'Resilience, Psychological'] | 25,416,685 | [['F01.058'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.686.508.100'], ['G07.345.124'], ['H02.403.355'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['F02.418', 'N01.400.500'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.4... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Somatostatin receptor subtypes in human type 2 diabetic islets. | OBJECTIVES: Somatostatin inhibits hormone release through 5 G protein-coupled somatostatin receptors (sst1-sst5). However, the role of somatostatin in islet physiology is not fully known. The immunoreactivity to sst1 to sst5 in normal human endocrine pancreas has been described. The present study reports the expression... | ['Aged', 'Aged, 80 and over', 'Autopsy', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Immunohistochemistry', 'Islets of Langerhans', 'Male', 'Pancreatic Polypeptide-Secreting Cells', 'Protein Isoforms', 'Receptors, Somatostatin', 'Somatostatin-Secreting Cells'] | 20,182,388 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
Treatment of respiratory failure with inhaled nitric oxide and high- frequency ventilation in an infant with respiratory syncytial virus pneumonia and bronchopulmonary dysplasia. | In a 7-month-old infant with bronchopulmonary dysplasia and respiratory syncytial virus (RSV) pneumonia, we have shown an additive effect of high-frequency ventilation (HFV) and inhaled nitric oxide (iNO) in terms of improved oxygenation and the avoidance of extracorporeal membrane oxygenation. Apparently, the combined... | ['Administration, Inhalation', 'Bronchopulmonary Dysplasia', 'High-Frequency Ventilation', 'Humans', 'Infant', 'Infant, Newborn', 'Nitric Oxide', 'Pneumonia, Viral', 'Respiratory Insufficiency', 'Respiratory Syncytial Virus Infections', 'Treatment Outcome'] | 9,817,963 | [['E02.319.267.050'], ['C08.381.520.750.500', 'C16.614.521.125'], ['E02.041.625.508', 'E02.880.820.508'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['C01.748.610.763', 'C01.925.705', 'C08.381.677.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Airway foreign bodies in pediatric patients: anatomic location of foreign body affects complications and outcomes. | BACKGROUND: Airway foreign bodies (FB) are a common medical emergency within the pediatric population. While deaths are not uncommon, the in-hospital mortality rates and correlation with anatomic location of the airway foreign body have not been previously reported.METHODS: The KID database was reviewed for 2003, 2006,... | ['Adolescent', 'Airway Obstruction', 'Bronchoscopy', 'Child', 'Child, Preschool', 'Female', 'Foreign Bodies', 'Hospital Mortality', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Male', 'Respiratory System', 'Retrospective Studies', 'United States'] | 27,738,825 | [['M01.060.057'], ['C08.618.846.185'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['M01.060.406'], ['M01.060.406.448'], ['C26.392'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Individual electrophoretic mobilities of liposomes and acidic organelles displaying pH gradients across their membranes. | This report focuses on measuring the individual electrophoretic mobilities of liposomes with different pH gradients across their membrane using capillary electrophoresis with laser-induced fluorescence detection (CE-LIF). The results from the individual analysis of liposomes show that, using surface electrostatic theor... | ['Animals', 'Cell Line', 'Electrophoresis', 'Hydrogen-Ion Concentration', 'Liposomes', 'Models, Chemical', 'Organelles', 'Phospholipids'] | 17,402,758 | [['B01.050'], ['A11.251.210'], ['E05.196.401', 'E05.301.300'], ['G02.300'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['E05.599.495'], ['A11.284.430.214.190.875'], ['D10.570.755']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Protease activation and the signal transduction pathway regulating motility in sperm from the water strider Aquarius remigis. | Many motile processes are regulated such that movement occurs only upon activation of a signaling cascade. Sperm from a variety of species are initially quiescent and must be activated prior to beating. The signaling events leading to the activation and regulation of sperm motility are not well characterized. Mature se... | ['Animals', 'Calcium', 'Egtazic Acid', 'Heteroptera', 'MAP Kinase Signaling System', 'Male', 'Marine Toxins', 'Oxazoles', 'Phosphorylation', 'Protein Kinase Inhibitors', 'Protein Kinases', 'Receptor, PAR-2', 'Signal Transduction', 'Sperm Motility', 'Spermatozoa', 'Staurosporine', 'Thapsigargin', 'Trypsin'] | 22,278,949 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.092.782.258.368.257', 'D02.241.081.018.269'], ['B01.050.500.131.617.412.420'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['D23.946.580'], ['D03.383.129.462'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['D27.505.519.389.755'], ['D08.811... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The application of in vivo laser scanning confocal microscopy as a tool of conjunctival in vivo cytology in the diagnosis of dry eye ocular surface disease. | PURPOSE: To evaluate the applicability of in vivo laser scanning confocal microscopy as a tool of conjunctival cytology in a prospective case-control study.METHODS: Nineteen right eyes of 19 Sjogren's syndrome dry eye patients (19 females; mean age: 55.8±15 years), and 18 right eyes of 18 normal healthy control subject... | ['Case-Control Studies', 'Cell Nucleus', 'Conjunctiva', 'Cytological Techniques', 'Epithelial Cells', 'Female', 'Humans', 'Male', 'Microscopy, Confocal', 'Middle Aged', "Sjogren's Syndrome", 'Tears'] | 21,139,693 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A09.371.060.200', 'A09.371.337.168'], ['E01.370.225.500', 'E05.200.500', 'E05.242'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.395', 'E05.595.395'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reprogramming of Vibrio harveyi gene expression during adaptation in cold seawater. | The life and survival of the marine bacterium Vibrio harveyi during its adaptation in natural aquatic systems is highly influenced by the availability of nutrients and temperature. To learn about adaptation strategies evolved by this bacterium to cope with drastic temperature downshifts and nutrients depletion, we have... | ['Adaptation, Physiological', 'Cold Temperature', 'Gene Expression', 'Gene Expression Regulation, Bacterial', 'Seawater', 'Vibrio'] | 24,102,529 | [['G07.025', 'G16.012.500'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G05.297'], ['G05.308.300'], ['G16.500.275.725.500'], ['B03.440.450.900.859', 'B03.660.250.830.830']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Affinity of cefmenoxime for beta-lactamases: an analysis. | The interactions of cefmenoxime with beta-lactamases in comparison with cefotaxime, moxalactam, cefoperazone, and ceftazidime have been determined. On-line computerized microacidimetry allowed determination of the affinity of these compounds with the enzymes, which was characterized by Km values. The beta-lactamases th... | ['Bacteria', 'Cefmenoxime', 'Cefotaxime', 'Cephalosporinase', 'Cephalosporins', 'Hydrolysis', 'Kinetics', 'Moxalactam', 'Penicillinase', 'beta-Lactamases'] | 6,097,119 | [['B03'], ['D02.065.589.099.249.190.190.125', 'D02.886.665.074.190.190.125', 'D03.633.100.300.249.190.190.125'], ['D02.065.589.099.249.190.190', 'D02.886.665.074.190.190', 'D03.633.100.300.249.190.190'], ['D08.811.277.087.180.229'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.300.249'], ['G02.380'], ['G01.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
E. Graeme Robertson--dynamics in fluid and light. | An eponymous lecture at the Australian and New Zealand Association of Neurologists Annual Scientific Meeting commemorates E. Graeme Robertson (1903-75), and some neurologists will know that particular Australian practices in clinical neurology, so far as they exist, have origins in his career. This is a historical arti... | ['Architecture', 'Australia', 'History, 20th Century', 'Humans', 'Nervous System Diseases', 'Neurology', 'Pneumoencephalography'] | 23,151,435 | [['J01.086'], ['Z01.639.100', 'Z01.678.100.373'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10'], ['H02.403.600'], ['E01.370.350.578.937.620', 'E01.370.350.700.560.620', 'E01.370.350.700.625.620', 'E01.370.376.537.750.620', 'E05.629.937.620']] | ['Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Humanities [K]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 |
Isoflavanones from the heartwood of Swartzia polyphylla and their antibacterial activity against cariogenic bacteria. | The methanolic extract of Swartzia polyphylla DC. heartwood had antibacterial activity against cariogenic bacteria, the mutans Streptococci. The chromatographic purification of the extract afforded seven flavonoids. Among them, three known isoflavanones, dihydrobiochanin A, ferreirin and darbergioidin, and one new isof... | ['Anti-Bacterial Agents', 'Chromatography, High Pressure Liquid', 'Circular Dichroism', 'Culture Media', 'Flavonoids', 'Isoflavones', 'Microbial Sensitivity Tests', 'Streptococcus', 'Structure-Activity Relationship', 'Trees'] | 1,477,911 | [['D27.505.954.122.085'], ['E05.196.181.400.300'], ['E05.196.867.151'], ['D27.720.470.305', 'E07.206'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['D03.383.663.283.266.450.400', 'D03.633.100.150.266.450.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['B03.353.750.737.872', 'B03.510.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interactions of insulin-mimetic zinc(II) complexes with cell constituents: glutathione and ATP. | Ternary complex formation of some potent insulin-mimetic zinc(II) complexes of bidentate ligands: maltol and 3-hydroxy-1,2-dimethyl-pyridinone with (O,O), 2-picolinic acid and 6-methylpicolinic acid with (N,O) and the tridentate 2,6-dipicolinic acid with (O,N,O) coordination modes was studied in aqueous solutions by pH... | ['3T3-L1 Cells', 'Adenosine Triphosphate', 'Animals', 'Biomimetic Materials', 'Glutathione', 'Insulin', 'Ligands', 'Mice', 'Organometallic Compounds', 'Oxidoreductases', 'Potentiometry', 'Spectrum Analysis', 'Zinc'] | 18,282,604 | [['A11.251.210.100.775.800', 'A11.329.228.100.775.800'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['J01.637.087'], ['D12.644.456.448'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D27.720.470.480'], ['B01.050.150.900.649.313.992.635.505.500'], ['D... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Ultrasensitive detection of bacteria by microchip electrophoresis based on multiple-concentration approaches combining chitosan sweeping, field-amplified sample stacking, and reversed-field stacking. | In this paper we describe an on-chip multiple-concentration method combining chitosan (CS) sweeping, reversed-field stacking, and field-amplified sample stacking for highly efficient detection of bacteria. Escherichia coli was selected as a model bacterium to investigate the efficiency of this multiple-concentration me... | ['Cetrimonium', 'Cetrimonium Compounds', 'Chitosan', 'Electrophoresis, Microchip', 'Escherichia coli', 'Water Microbiology'] | 22,242,961 | [['D02.092.877.883.111.500', 'D02.675.276.190.500'], ['D02.092.877.883.111', 'D02.675.276.190'], ['D05.750.078.139.500', 'D09.698.211.500'], ['E05.196.401.190.500', 'E05.588.465.340'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['H01.158.273.540.274.777', 'N06.850.425.450']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Preliminary characterization, androgen-dependence and ontogeny of an abundant protein from mouse vas deferens. | Polyacrylamide gel electrophoresis analysis revealed that the vas deferens of adult mouse contains a major protein. Mouse vas deferens protein is a basic glycoprotein with a molecular weight of 34,800 +/- 300. The protein represents 17 +/- 0.7% and 42 +/- 2.4% of soluble proteins from homogenate and luminal fluid respe... | ['Animals', 'Electrophoresis, Polyacrylamide Gel', 'Glycoproteins', 'Male', 'Mice', 'Mice, Inbred Strains', 'Orchiectomy', 'Sexual Maturation', 'Vas Deferens'] | 3,411,574 | [['B01.050'], ['E05.196.401.402', 'E05.301.300.319'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'], ['E04.270.282.679', 'E04.950.165.679', 'E04.950.774.860.618'], ['G07.345.750.750', 'G08.686.841.750'], ['A05.360.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phytochrome from Agrobacterium tumefaciens has unusual spectral properties and reveals an N-terminal chromophore attachment site. | Phytochromes are photochromic photoreceptors with a bilin chromophore that are found in plants and bacteria. The soil bacterium Agrobacterium tumefaciens contains two genes that code for phytochrome-homologous proteins, termed Agrobacterium phytochrome 1 and 2 (Agp1 and Agp2). To analyze its biochemical and spectral pr... | ['Agrobacterium tumefaciens', 'Amino Acid Sequence', 'Base Sequence', 'Binding Sites', 'DNA Primers', 'Molecular Sequence Data', 'Molecular Structure', 'Mutation', 'Phosphorylation', 'Phytochrome', 'Sequence Homology, Amino Acid'] | 12,186,972 | [['B03.440.400.425.700.024.050', 'B03.660.050.662.024.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['L01.453.245.667'], ['G02.111.570', 'G02.466'], ['G05.365.590'], ['G02.111... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Phase II trial of oxaliplatin and tegafur/uracil and oral folinic acid for advanced or metastatic colorectal cancer in elderly patients. | OBJECTIVES: Colorectal cancer is usually diagnosed in elderly patients. Since there is clear evidence that such patients are under-treated and under-represented or even excluded from clinical studies and there are no reliable and prospective data on the feasibility and efficacy of an oxaliplatin (L-OHP)-based chemother... | ['Administration, Oral', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Colorectal Neoplasms', 'Female', 'Humans', 'Infusions, Intravenous', 'Leucovorin', 'Male', 'Neoplasm Metastasis', 'Organoplatinum Compounds', 'Oxaliplatin', 'Tegafur', 'Treatment Outcome', 'Uracil'] | 16,118,508 | [['E02.319.267.100'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['B01.050... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The hot-film anemometer--a method for blood velocity determination. II. In vivo comparison with the electromagnetic blood flowmeter. | Using a constant temperature hot-film anemometer and an electromagnetic blood flowmeter, volumetric flows and velocity profiles were registered in the pulmonary artery, ascending aorta, abdominal aorta and superior vena cava of mongrel dogs. The anemometer registered in 3 out of 4 dogs in the ascending aorta and in 4 o... | ['Animals', 'Aorta', 'Aorta, Abdominal', 'Blood Flow Velocity', 'Blood Pressure', 'Dogs', 'Electrocardiography', 'Electromagnetic Phenomena', 'Equipment and Supplies', 'Pulmonary Artery', 'Rheology', 'Vena Cava, Superior'] | 6,447,602 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predictors of hazardous drinking, tobacco smoking and physical inactivity in vocational school students. | BACKGROUND: Tobacco smoking, hazardous drinking and physical inactivity during adolescence are risk factors that are associated with poorer health in adulthood. The identification of subgroups of young people with a high prevalence of one or more of these risk factors allows an optimised allocation of preventive measur... | ['Adolescent', 'Adult', 'Alcohol Drinking', 'Exercise', 'Female', 'Humans', 'Male', 'Smoking', 'Students', 'Switzerland', 'Vocational Education', 'Young Adult'] | 23,672,294 | [['M01.060.057'], ['M01.060.116'], ['F01.145.317.269'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.805'], ['M01.848'], ['Z01.542.883'], ['I02.233.862'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
The changing role of the nurse teacher. | This paper concludes a series on the findings from a study on the emerging role of nurse teachers in Project 2000 programmes. The various aspects of the study, including the literature review and methodology, have been previously discussed (Crotty & Butterworth 1992, Crotty 1992, Crotty 1993a,b,c,d). This paper highlig... | ['Delphi Technique', 'Education, Nursing', 'Faculty, Nursing', 'Humans', 'Job Description', 'Organizational Innovation', 'Teaching'] | 8,121,343 | [['L01.906.197'], ['I02.358.462'], ['M01.526.485.390', 'M01.526.702.250.473', 'N02.360.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.677.410'], ['N04.452.610'], ['I02.903']] | ['Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Wire tethering or 'bowstringing' as a long-term hardware-related complication of deep brain stimulation. | BACKGROUND: Widely reported long-term complications following implantation of deep brain stimulation (DBS) hardware include breakage of electrode leads, internal pulse generator (IPG) failure, skin erosions and infection. Here we report on a rarely described problem that arises from formation of scar tissue adhesions a... | ['Adult', 'Cicatrix', 'Deep Brain Stimulation', 'Dystonia', 'Electrodes, Implanted', 'Epilepsy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Parkinson Disease', 'Retrospective Studies'] | 19,752,594 | [['M01.060.116'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['E02.331.300', 'E04.190'], ['C10.597.350.300', 'C23.888.592.350.300'], ['E07.305.250.319', 'E07.695.202'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.228.140.079.862.500', 'C10.228.662.600... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Life Course Socioeconomic Position and Subclinical Disease: The Jackson Heart Study. | OBJECTIVES: African Americans experience higher rates of cardiovascular disease (CVD) and lower childhood and adult socioeconomic position (SEP). Research that examines the associations of multiple measures of SEP with subclinical CVD markers among African Americans is limited.METHODS: Data from the Jackson Heart Study... | ['Adult', 'African Americans', 'Aged', 'Biomarkers', 'Cardiovascular Diseases', 'Carotid Intima-Media Thickness', 'Coronary Artery Disease', 'Cross-Sectional Studies', 'Female', 'Humans', 'Hypertrophy, Left Ventricular', 'Male', 'Middle Aged', 'Prevalence', 'Risk Factors', 'Social Class'] | 27,440,975 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['D23.101'], ['C14'], ['E01.370.350.850.150', 'E01.370.370.180', 'G09.330.210'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A reinforcement-learning-based approach to enhance exhaustive protein loop sampling. | MOTIVATION: Loop portions in proteins are involved in many molecular interaction processes. They often exhibit a high degree of flexibility, which can be essential for their function. However, molecular modeling approaches usually represent loops using a single conformation. Although this conformation may correspond to... | ['Algorithms', 'Models, Molecular', 'Protein Conformation', 'Proteins', 'Software'] | 31,504,192 | [['G17.035', 'L01.224.050'], ['E05.599.595'], ['G02.111.570.820.709'], ['D12.776'], ['L01.224.900']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The roles of phytochromes in elongation and gravitropism of roots. | Gravitropic orientation and the elongation of etiolated hypocotyls are both regulated by red light through the phytochrome family of photoreceptors. The importance of phytochromes A and B (phyA and phyB) in these red light responses has been established through studies using phy mutants. To identify the roles that phyt... | ['Arabidopsis', 'Arabidopsis Proteins', 'Gravitropism', 'Light', 'Mutation', 'Photoreceptor Cells', 'Phytochrome', 'Phytochrome A', 'Phytochrome B', 'Plant Roots', 'Protein-Serine-Threonine Kinases', 'Transcription Factors'] | 15,695,459 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G07.345.249.845.400', 'G15.920.400'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['G05.365.590'], ['A08.675.650.850.625', 'A08.675.650.915.937', 'A08.800.950.937', 'A09.371.729.831.625', 'A11.671.650.850.625', 'A11.671.6... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Neuromuscular block control during and after anaesthesia (author's transl)]. | During many years the clinician's requirements for neuromuscular blocking drugs are satisfied by clinical investigations. Electromyographic recordings which are a satisfactory method are not useful in current practice. The use of nerve stimulators as Churchill Davidson apparatus modified for train of four impulses must... | ['Adult', 'Aged', 'Aging', 'Anesthesia', 'Child', 'Child, Preschool', 'Electromyography', 'Female', 'Humans', 'Intraoperative Period', 'Monitoring, Physiologic', 'Muscle Relaxation', 'Neuromuscular Nondepolarizing Agents', 'Postoperative Complications', 'Respiratory Insufficiency', 'Ulnar Nerve'] | 161,146 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['E03.155'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374', 'N02.421.585.753.374'], ['E01.370.520'], ['G11.427.494.554'], ['D27.505.696.663.700.710.575'], ['C23.550.767... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. | Recent studies identified the adaptor protein Ajuba as a positive regulator of Yes-associated protein (YAP) oncogenic activity through inhibiting large tumor suppressor (Lats1/2) core kinases of the Hippo pathway, a signaling pathway that plays important roles in cancer. In this study, we define a novel mechanism for p... | ['Amino Acid Sequence', 'Animals', 'CDC2 Protein Kinase', 'Carcinogenesis', 'Cell Cycle', 'Cell Proliferation', 'Cyclin B', 'HeLa Cells', 'Humans', 'LIM Domain Proteins', 'Phosphorylation', 'Sequence Homology, Amino Acid'] | 27,226,586 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D08.811.913.696.620.682.700.646.500.500.250', 'D08.811.913.696.620.682.700.646.500.984.500', 'D12.644.360.250.067.249', 'D12.644.360.250.580.500', 'D12.776.167.200.067.249', 'D12.776.167.200.580.500', 'D12.776.476.250.067.249', 'D12.776.476.250.580.500', 'D12.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Knowledge and practice in cardiovascular disease prevention among hospital registered nurses: a cross-sectional study. | AIMS AND OBJECTIVES: To investigate the knowledge and clinical practices of cardiovascular disease prevention among registered nurses who worked on three major clinical units in Beijing hospitals.BACKGROUND: Health education on cardiovascular disease prevention is an important component of nursing practice; however, Ch... | ['Adult', 'Cardiovascular Diseases', 'Cardiovascular Nursing', 'China', 'Clinical Competence', 'Cross-Sectional Studies', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', "Nurse's Role", 'Nursing Staff, Hospital', 'Patient Education as Topic', 'Risk Factors', 'Surveys and Questionnair... | 27,906,479 | [['M01.060.116'], ['C14'], ['H02.478.676.112', 'N02.421.533.099'], ['Z01.252.474.164'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116... | ['Named Groups [M]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
[Transconjunctival inferior blepharoplasty]. | The transconjunctival approach is the appropriate standard for lower eyelid blepharoplasty in patients presenting with lower eyelid herniated fat without excess skin. A transconjunctival incision is made approximately 2 mm below the tarsal border and extended inferiorly following a plane posterior to the orbital septum... | ['Adipose Tissue', 'Adult', 'Blepharoplasty', 'Blindness', 'Conjunctiva', 'Eyelids', 'Female', 'Humans', 'Middle Aged'] | 16,344,755 | [['A10.165.114'], ['M01.060.116'], ['E04.540.104', 'E04.680.275.090'], ['C10.597.751.941.162', 'C11.966.075', 'C23.888.592.763.941.162'], ['A09.371.060.200', 'A09.371.337.168'], ['A01.456.505.420.504', 'A09.371.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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