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Dipteran toxicity assays for determining the oral insecticidal activity of venoms and toxins. | The growing world population is placing an increasing demand on food production. In addition, abuse and misuse of chemical insecticides has led to the evolution of resistance in insect pests as well as environmental damage. Together, these developments have created a demand for new insecticidal compounds to facilitate ... | ['Administration, Oral', 'Animals', 'Biological Assay', 'Diptera', 'Insecticides', 'Lethal Dose 50', 'Sensitivity and Specificity', 'Toxicity Tests', 'Toxins, Biological', 'Venoms'] | 29,920,256 | [['E02.319.267.100'], ['B01.050'], ['E05.091'], ['B01.050.500.131.617.720.500.500.750'], ['D27.720.031.700.491', 'D27.888.723.491'], ['E05.940.402', 'G07.225.500', 'G07.690.773.875.750', 'G07.690.936.500.750'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Effect of EGF on the intracellular distribution of heat-shock proteins in A431 cells]. | The intracellular distribution of hsp70 and hdj1 was studied using immunofluorescent method. In nonstimulated cells hsp70 and hdj1 were observed in the cytoplasm of A431 cells. When 100 ng/ml EGF was added for 15 min, both hsp70 and hdj1 were accumulated in the nuclei. Later on (up to 1 h) hsp70 was exported from the n... | ['Antibodies, Monoclonal', 'Carcinoma, Squamous Cell', 'Cell Line, Tumor', 'Cell Nucleus', 'Cytoplasm', 'Enzyme Inhibitors', 'Epidermal Growth Factor', 'ErbB Receptors', 'Estrenes', 'Fluorescent Antibody Technique', 'HSP40 Heat-Shock Proteins', 'HSP70 Heat-Shock Proteins', 'Heat-Shock Proteins', 'Hot Temperature', 'Hum... | 15,216,634 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.214'], ['D27.505.519.389'], ['D06.472.317.350', 'D12.644.276.382.500',... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[The reduction of the maternal and neonatal risk based on a new outlook for care effected with the active involvement of the nuclear family in the pregnancy and labor]. | A socio-analytic investigation, showing mental images of health personnel and their influence on the course of pregnancy, child birth and child nursing has been performed at the Obstetrics and Neonatology Departments of Maria Vittoria Hospital, Torino, Italy. Through a statistical analysis on the mothers population dur... | ['Adolescent', 'Adult', 'Delivery, Obstetric', 'Female', 'Humans', 'Infant, Newborn', 'Italy', 'Nuclear Family', 'Obstetric Labor Complications', 'Postpartum Period', 'Pregnancy', 'Pregnancy Complications', 'Prenatal Care', 'Risk Factors', 'Sociology', 'Surveys and Questionnaires'] | 2,519,509 | [['M01.060.057'], ['M01.060.116'], ['E04.520.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['Z01.542.489'], ['F01.829.263.500', 'I01.880.853.150.500'], ['C13.703.420'], ['G08.686.702'], ['G08.686.784.769'], ['C13.703'], ['E02.760.786', 'N02.421.143.620.704', 'N02.421.585.786'], ['E05.318.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
New roles of glycosaminoglycans in á-synuclein aggregation in a cellular model of Parkinson disease. | The causes of Parkinson disease (PD) remain mysterious, although some evidence supports mitochondrial dysfunctions and á-synuclein accumulation in Lewy bodies as major events. The abnormal accumulation of á-synuclein has been associated with a deficiency in the ubiquitin-proteasome system and the autophagy-lysosomal pa... | ['1-Methyl-4-phenylpyridinium', 'Amino Acid Sequence', 'Apoptosis', 'Cathepsin D', 'Cell Line, Tumor', 'Glycosaminoglycans', 'Humans', 'Intracellular Space', 'Parkinson Disease', 'Protein Aggregates', 'Protein Transport', 'Proteolysis', 'alpha-Synuclein'] | 25,617,759 | [['D03.383.725.762.550'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G04.146.954.035'], ['D08.811.277.656.074.500.180', 'D08.811.277.656.224.187', 'D08.811.277.656.300.048.180'], ['A11.251.210.190', 'A11.251.860.180'], ['D09.698.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.082.750', 'A11.284.430'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Health care and social work education in a changing world. | This article examines two major challenges that beset contemporary social work education, namely, rapid and dramatic macro-level changes that are occurring in the social, political, economic and demographic realms and, also, the slow speed at which curriculum changes occur in institutions of higher education. Primarily... | ['Curriculum', 'Delivery of Health Care', 'Humans', 'Managed Care Programs', 'Organizational Innovation', 'Social Work', 'United States'] | 12,219,768 | [['I02.158'], ['N04.590.374', 'N05.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.800', 'N04.590.374.410'], ['N04.452.610'], ['I01.880.792', 'N02.421.849'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Motivational Interviewing to prevent dropout from an education and employment program for young adults: A randomized controlled trial. | This study tested the efficacy of Motivational Interviewing for improving retention at a "second chance" program in the United States for unemployed young adults who had not graduated high school (ages 18-24; 60% male). We investigated how Motivational Interviewing effects might be mediated by change talk (i.e., argume... | ['Adolescent', 'Educational Status', 'Employment', 'Female', 'Humans', 'Male', 'Motivation', 'Motivational Interviewing', 'Surveys and Questionnaires', 'Unemployment', 'Young Adult'] | 28,458,078 | [['M01.060.057'], ['N01.824.196'], ['N01.824.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['F02.784.176.279.500', 'F04.408.413.349.500', 'N02.421.461.363.349.500'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['N01.824.245.850'], ['M01.060.116.815']] | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The struggle of the diagnosed terminally ill person to maintain hope. | Clinical, empirical, and subjective data are used to explore the concept of hope as it is lived by persons who are diagnosed as terminally ill. Interviews with 11 men who were in stage 2 (asymptomatic) HIV disease explicate the form that hope takes and its role in promoting health when a person must cope with a serious... | ['Adaptation, Psychological', 'HIV Seropositivity', 'Humans', 'Male', 'Morale', 'Nursing Care', 'Terminal Care'] | 2,250,837 | [['F01.058'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.500', 'C01.925.782.815.616.400.500', 'C01.925.813.400.500', 'C20.673.480.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.477'], ['E02.760.611', 'N02.421.533'], ['E02.760.905', 'N02.421.585.905']] | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Treating low back pain resulted from lumbar degenerative instability using Chinese Tuina combined with core stability exercises: A randomized controlled trial. | BACKGROUND: The therapeutic effect of Tuina combined with core stability exercises on low back pain resulted from lumbar degenerative instability is unclear. This article aims to evaluate whether core stability exercises can improve the effect of Tuina in this regard.METHODS: This trial was designed as a randomized con... | ['Adult', 'Exercise Therapy', 'Female', 'Humans', 'Low Back Pain', 'Lumbosacral Region', 'Male', 'Medicine, Chinese Traditional', 'Middle Aged', 'Musculoskeletal Manipulations', 'Spinal Diseases'] | 27,062,947 | [['M01.060.116'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.107.400'], ['A01.923.176.519'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['M01.060.116.630'], ['E02.190.599', 'E02.779.867', 'E02.831.535.867'], ['C05.116.90... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Normative data of quantitative thermal and vibratory thresholds in normal subjects in Taiwan: gender and age effect. | BACKGROUND: Quantitative sensory testing has gained popularity as a tool in the diagnosis of peripheral neuropathies. This study aims to establish normative data of quantitative thermal and vibratory thresholds in normal subjects in Taiwan. In addition, we also examined the effect of age and gender differences on these... | ['Adult', 'Age Factors', 'Aged', 'Body Height', 'Cold Temperature', 'Female', 'Hot Temperature', 'Humans', 'Male', 'Middle Aged', 'Pain Threshold', 'Reference Values', 'Sensory Thresholds', 'Sex Factors', 'Vibration'] | 10,418,177 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Thrombocytopenia in dogs with anticoagulant rodenticide-induced hemorrhage: eight cases (1990-1995). | Thrombocytopenia was documented in eight of 11 dogs with anticoagulant rodenticide-induced hemorrhage. Thrombocytopenia was transient and generally mild-to-moderate, but it became marked (i.e., less than 30,000 platelets/microl) in two cases. Petechial hemorrhages were not noted in any case. There was no relationship b... | ['Animals', 'Anticoagulants', 'Blood Proteins', 'Diagnosis, Differential', 'Dog Diseases', 'Dogs', 'Hematocrit', 'Hemorrhage', 'Immunoglobulin G', 'Isotonic Solutions', 'Platelet Count', 'Poisoning', 'Rodenticides', 'Thrombocytopenia'] | 9,278,117 | [['B01.050'], ['D27.505.954.502.119'], ['D12.776.124'], ['E01.171'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['C23.550.414'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['D26.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Establishment and characterization of a cell line [GCH-1 (m)] highly metastasizing to the lung in nude mice]. | A new cell line having the ability to metastasize to the lungs in nude mice was established from GCH-1 (human choriocarcinoma cell line). Twenty CD-1 nude mice were injected with GCH-1 cells subcutaneously. A solitary metastatic pulmonary nodule appeared in only one of these mice. The pulmonary nodule was removed and m... | ['Animals', 'Cell Line', 'Choriocarcinoma', 'Female', 'Humans', 'Lung Neoplasms', 'Mice', 'Mice, Nude', 'Neoplasm Transplantation', 'Neoplastic Cells, Circulating', 'Pregnancy', 'Uterine Neoplasms'] | 3,585,108 | [['B01.050'], ['A11.251.210'], ['C04.557.465.955.207', 'C04.557.470.200.025.455', 'C04.850.908.208', 'C13.703.720.949.208'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intractable Crohn's colitis and perianal disease responding to cyclophosphamide and epirubicin. | A case is reported where intractable Crohn's disease responded to chemotherapy for breast carcinoma. The drug most likely responsible was cyclophosphamide. Cyclophosphamide may have a role in the management of inflammatory bowel disease, but this needs to be confirmed before it can be recommended as a treatment option. | ['Alkylating Agents', 'Antibiotics, Antineoplastic', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Chemotherapy, Adjuvant', 'Colitis', 'Crohn Disease', 'Cyclophosphamide', 'Epirubicin', 'Female', 'Humans', 'Immunosuppressive Agents', 'Mastectomy', 'Middle Aged', 'Rectal Diseases'] | 9,398,818 | [['D27.505.519.124', 'D27.888.569.035'], ['D27.505.954.248.106'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['E02.186.170', 'E02.319.170'], ['C06.405.205.265', 'C06.405.469.158.188'], ['C06.405.205.731.500', 'C06.405.469.432... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Pelvic ostheomyelitis: diagnostics and treatment]. | Results of treatment of 223 patients with ostheomyelitis of various etiology and localization were analyzed. Such aspects as diagnostic difficulties, polifocal type of the disease, sepsis development on the background of pelvic ostheomyelitis were discussed. Ostheoscintygraphy, magnetic resonance imaging and computed t... | ['Adolescent', 'Adult', 'Aged', 'Anti-Bacterial Agents', 'Chronic Disease', 'Combined Modality Therapy', 'Cutaneous Fistula', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Osteomyelitis', 'Pelvic Bones', 'Pelvis', 'Pressure Ulcer', 'Suppuration', 'Tomography, X-Ray Computed', 'Treatment Outc... | 21,606,913 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.085'], ['C23.550.291.500'], ['E02.186'], ['C17.800.135', 'C23.300.575.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C01.160.495', 'C05.116.165.495'], ['A02.835.232.043.825'], ['A01.923.600... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
S1P1 receptor localization confers selectivity for Gi-mediated cAMP and contractile responses. | Adult mouse ventricular myocytes express S1P(1), S1P(2), and S1P(3) receptors. S1P activates Akt and ERK in adult mouse ventricular myocytes through a pertussis toxin-sensitive (G(i/o)-mediated) pathway. Akt and ERK activation by S1P are reduced approximately 30% in S1P(3) and 60% in S1P(2) receptor knock-out myocytes.... | ['Animals', 'Cyclic AMP', 'Enzyme Activation', 'GTP-Binding Protein alpha Subunits, Gi-Go', 'Gene Expression Regulation', 'Isoproterenol', 'Lysophospholipids', 'Male', 'Mice', 'Mice, Knockout', 'Mitogen-Activated Protein Kinases', 'Myocardial Contraction', 'Myocytes, Cardiac', 'Oxadiazoles', 'Pertussis Toxin', 'Protein... | 18,296,752 | [['B01.050'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['G02.111.263', 'G03.328'], ['D08.811.277.040.330.300.200.100.200', 'D12.644.360.360.100.200', 'D12.776.157.325.332.100.200', 'D12.776.476.375.100.200', 'D12.776.543.325.100.200'], ['G05.308'], ['D02.033.100.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Suggested guidelines for using systemic antimicrobials in bacterial skin infections: part 2-- antimicrobial choice, treatment regimens and compliance. | Systemic antimicrobials are critically important in veterinary healthcare, and resistance is a major concern. Antimicrobial stewardship will be important in maintaining clinical efficacy by reducing the development and spread of antimicrobial resistance. Bacterial skin infections are one of the most common reasons for ... | ['Animals', 'Anti-Infective Agents', 'Cat Diseases', 'Cats', 'Choice Behavior', 'Dog Diseases', 'Dogs', 'Medication Adherence', 'Practice Guidelines as Topic', 'Skin Diseases, Bacterial'] | 23,292,948 | [['B01.050'], ['D27.505.954.122'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['F02.463.785.373.346'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['F01.100.150.750.500.600.500', 'F01.145.488.887.500.600.500', 'N05.300.150.800.500.600.500'], ['N04.761.700.350.650', 'N05.700.350.650'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Vasopressin, oxytocin, dynorphin, enkephalin and corticotrophin-releasing factor mRNA stimulation in the rat. | 1. Cryostat sections were cut through the hypothalamus of rats which had been given a 2% (w/v) NaCl solution to drink for up to 12 days. 2. In situ hybridization histochemistry was performed on these sections using synthetic oligonucleotide probes against part of the precursor sequence for vasopressin, oxytocin, dynorp... | ['Animals', 'Corticotropin-Releasing Hormone', 'Dynorphins', 'Endorphins', 'Enkephalins', 'Hypothalamus', 'Male', 'Oxytocin', 'Paraventricular Hypothalamic Nucleus', 'RNA, Messenger', 'Rats', 'Rats, Inbred Strains', 'Supraoptic Nucleus', 'Vasopressins'] | 2,895,179 | [['B01.050'], ['D06.472.699.327.740.140', 'D12.644.400.400.740.140', 'D12.644.548.365.740.140', 'D12.776.631.650.405.740.140'], ['D12.644.400.575.180', 'D12.776.631.650.575.180'], ['D12.644.400.575.241', 'D12.776.631.650.575.241'], ['D12.644.400.575.281', 'D12.776.631.650.575.281'], ['A08.186.211.180.497', 'A08.186.211... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glutamate receptors on myelinated spinal cord axons: I. GluR6 kainate receptors. | OBJECTIVE: The deleterious effects of glutamate excitotoxicity are well described for central nervous system gray matter. Although overactivation of glutamate receptors also contributes to axonal injury, the mechanisms are poorly understood. Our goal was to elucidate the mechanisms of kainate receptor-dependent axonal ... | ['Animals', 'Axons', 'Calcium', 'Calcium Channels, L-Type', 'Cysteine', 'Egtazic Acid', 'Excitatory Amino Acid Antagonists', 'Glutamic Acid', 'Hydroxocobalamin', 'Male', 'Microscopy, Confocal', 'Myoglobin', 'Nerve Fibers, Myelinated', 'Nitric Oxide', 'PDZ Domains', 'Peptides', 'Protein Multimerization', 'Rats', 'Rats, ... | 19,224,535 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.530.400.150.400', 'D12.776.543.550.450.150.400', 'D12.776.543.585.400.150.400'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D0... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structural flexibility and the thermodynamics of helix exchange constrain attenuation and allosteric activation of hammerhead ribozyme TRAPs. | Perturbations of precleavage equilibria in RNA-cleaving ribozymes can be exploited to control cleavage kinetics. In the targeted ribozyme-attenuated probes (TRAP) design, antisense and attenuator sequences are appended onto the catalytic core of a ribozyme or deoxyribozyme. The attenuator anneals to conserved bases in ... | ['Allosteric Regulation', 'Base Sequence', 'Enzyme Activation', 'Enzyme Repression', 'Hydrolysis', 'Kinetics', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'Nucleic Acid Heteroduplexes', 'Oligonucleotides, Antisense', 'Protein Binding', 'RNA Probes', 'RNA, Catalytic', 'Substrate Specificity', 'Thermodynamics... | 14,636,055 | [['G02.111.044'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.263', 'G03.328'], ['G05.308.320.300'], ['G02.380'], ['G01.374.661', 'G02.111.490'], ['L01.453.245.667'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.444.500'], ['D13.150.480', 'D13.444.600.150.640', 'D13.695.578.424.480', 'D27.720.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Pediatric Outcomes After Regulatory Mandates for Sepsis Care. | BACKGROUND: In 2013, New York introduced regulations mandating that hospitals develop pediatric-specific protocols for sepsis recognition and treatment.METHODS: We used hospital discharge data from 2011 to 2015 to compare changes in pediatric sepsis outcomes in New York and 4 control states: Florida, Massachusetts, Mar... | ['Adolescent', 'Child', 'Child, Preschool', 'Cohort Studies', 'Female', 'Hospital Mortality', 'Humans', 'Infant', 'Interrupted Time Series Analysis', 'Male', 'Outcome Assessment, Health Care', 'Retrospective Studies', 'Sepsis', 'United States'] | 32,605,994 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Recovery after hyperpyrexia during beta-haemolytic streptococcal septicaemia. | A patient with septicaemia caused by a beta-haemolytic streptococcus developed a high fever during which his temperature reached 44 degrees C (112 degrees F). Although body temperatures above 42 degrees C are unusual, in this case the high temperature was rapidly brought under control and the infection was successfully... | ['Adult', 'Fever', 'Humans', 'Male', 'Sepsis', 'Streptococcal Infections'] | 6,886,448 | [['M01.060.116'], ['C23.888.119.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.757', 'C23.550.470.790.500'], ['C01.150.252.410.890']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Long-term results of a second endoscopic third ventriculostomy in children: retrospective analysis of 40 cases. | OBJECTIVE: To evaluate retrospectively the operative findings and long-term results of a repeat endoscopic third ventriculostomy (ETV) in pediatric hydrocephalic patients readmitted after the first procedure with symptoms and/or signs of intracranial hypertension and/or radiological evidence of increased ventricular di... | ['Adolescent', 'Child', 'Child, Preschool', 'Endoscopy', 'Female', 'Humans', 'Hydrocephalus', 'Infant', 'Kaplan-Meier Estimate', 'Longitudinal Studies', 'Magnetic Resonance Imaging', 'Male', 'Pediatrics', 'Recurrence', 'Retrospective Studies', 'Tomography, X-Ray Computed', 'Ultrasonography', 'Ventriculostomy'] | 19,687,699 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.602'], ['M01.060.703'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Online LI-rTMS during a Visual Learning Task: Differential Impacts on Visual Circuit and Behavioral Plasticity in Adult Ephrin-A2A5-/- | Repetitive transcranial magnetic stimulation (rTMS) induces plasticity in normal and abnormal neural circuitries, an effect that may be influenced by intrinsic brain activity during treatment. Here, we study potential synergistic effects between low-intensity rTMS (LI-rTMS) and concurrent neural activity in promoting c... | ['Animals', 'Behavior, Animal', 'Choice Behavior', 'Discrimination, Psychological', 'Ephrin-A2', 'Ephrin-A5', 'Female', 'Geniculate Bodies', 'Learning', 'Male', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Neuronal Plasticity', 'Photic Stimulation', 'Psychomotor Performance', 'Transcranial Magnetic Stimulation', 'Visual Co... | 29,464,193 | [['B01.050'], ['F01.145.113'], ['F02.463.785.373.346'], ['F02.463.593.257'], ['D12.644.276.500.200', 'D12.776.395.550.448.310', 'D12.776.467.500.200', 'D12.776.543.287.200', 'D12.776.543.484.500.310', 'D12.776.543.550.418.310', 'D23.529.500.200'], ['D12.644.276.500.500', 'D12.776.395.550.448.340', 'D12.776.467.500.500'... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Epithelial-mesenchymal interaction and insulin-like growth factors in hyperoxic lung injury. | To investigate the role of epithelial-mesenchymal interaction on oxygen-induced lung injury, we used a coculture model with lung fibroblasts (FB) embedded between 2 layers of collagen gel with and without human tracheobronchial epithelial cells (HTBE), and studied the effect of hyperoxia on the directed migration of FB... | ['Cell Communication', 'Cell Division', 'Cell Movement', 'Coculture Techniques', 'Collagen', 'Epithelial Cells', 'Fibroblasts', 'Gels', 'Humans', 'Hyperoxia', 'Insulin-Like Growth Factor I', 'Insulin-Like Growth Factor II', 'Lung', 'Mesoderm', 'RNA, Messenger', 'Receptor, IGF Type 2'] | 10,643,566 | [['G04.085'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.198', 'G07.568.500.180'], ['E05.481.500.374'], ['D05.750.078.280', 'D12.776.860.300.250'], ['A11.436'], ['A11.329.228'], ['D20.280.320', 'D26.255.165.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.567'],... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hemophagocytic lymphohistiocytosis associated with a parvovirus B19 infection during pregnancy. | BACKGROUND: Hemophagocytic lymphohistiocytosis is potentially fatal. Prompt diagnosis and initiation of treatment are critical for ensuring the best possible prognosis.CASE: We present a case of parvovirus B19 infection related to hemophagocytic lymphohistiocytosis during pregnancy. The patient experienced fever and pa... | ['Adult', 'Female', 'Humans', 'Lymphohistiocytosis, Hemophagocytic', 'Parvoviridae Infections', 'Parvovirus B19, Human', 'Pregnancy', 'Pregnancy Complications, Infectious'] | 25,004,318 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.604.250.410.575'], ['C01.925.256.700'], ['B04.280.580.650.200.650'], ['G08.686.784.769'], ['C01.674', 'C13.703.700']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A surface charge dependent enhanced Th1 antigen-specific immune response in lymph nodes by transfersome-based nanovaccine-loaded dissolving microneedle-assisted transdermal immunization. | The efficient delivery of vaccines to draining lymph nodes and the induction of robust local immune responses are crucial for immunotherapy. Transdermal administration has been evidenced to facilitate the delivery of ingredients to lymph nodes. In this study, transfersomes with opposite surface charges were applied for... | ['Administration, Cutaneous', 'Animals', 'Dendritic Cells', 'Female', 'Immunity, Cellular', 'Immunity, Humoral', 'Interferon-gamma', 'Interleukin-2', 'Lymph Nodes', 'Male', 'Mice, Inbred BALB C', 'Needles', 'Ovalbumin', 'Rats, Sprague-Dawley', 'Th1 Cells', 'Vaccination', 'Vaccines'] | 31,389,952 | [['E02.319.267.120.060'], ['B01.050'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['G12.450.050.400'], ['G12.450.050.420'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.529.374.480.615.350'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Spinal cord compression due to intraspinal syphilitic gumma in one patient. Clinical case]. | The involvement of the central nervous system by Treponema pallidum has increased in the past 20 years, particularly as a result of the human immunodeficiency virus (HIV) pandemic. However, tertiary forms, and especially syphilitic gumma, are increasingly rare as a result of the widespread use of penicillin. Spinal cor... | ['Female', 'Humans', 'Middle Aged', 'Neurosyphilis', 'Spinal Cord Compression'] | 23,320,318 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C01.150.252.223.600', 'C01.150.252.400.794.840.500.750', 'C01.150.252.400.840.500.750', 'C01.207.180.600', 'C10.228.228.180.600'], ['C10.228.854.761', 'C26.819.678']] | ['Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Protein turnover of breast muscle in germ-free and conventional chicks. | The effect of the gut microflora on protein turnover in pectoral muscle (M. pectoralis profundus) was studied by means of dietary infusion of L-[U-14C]phenylalanine and of massive dose injection of L-[4-3H]phenylalanine in chicks fed on a semi-purified casein-gelatin (SCG) diet until 19 d of age, and in those subsequen... | ['Animals', 'Arginine', 'Caseins', 'Chickens', 'Diet', 'Gelatin', 'Germ-Free Life', 'Intestines', 'Methionine', 'Muscle Proteins', 'Pectoralis Muscles', 'Phenylalanine'] | 4,063,297 | [['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G07.203.650.240'], ['D12.776.860.476'], ['G06.320'], ['A03.556.124'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acute Respiratory Distress Syndrome and Prone Positioning. | Acute respiratory distress syndrome continues to have high morbidity and mortality despite more than 50 years of research. The Berlin definition in 2012 established risk stratification based on degree of hypoxemia and the use of positive end-expiratory pressure. The use of prone positioning as a treatment modality has ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Critical Care', 'Female', 'Humans', 'Hypoxia', 'Male', 'Middle Aged', 'Positive-Pressure Respiration', 'Practice Guidelines as Topic', 'Prone Position', 'Respiration, Artificial', 'Respiratory Distress Syndrome'] | 30,523,012 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.760.190', 'N02.421.585.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.079'], ['M01.060.116.630'], ['E02.041.625.790', 'E02.880.820.790'], ['N04.761.700.350.650', 'N05.700.350.650'], ['G11.427.695.525'], ['E02.041.625', 'E02.365... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of pulse repetition frequency and scan step size on the dimensions of the lesions formed in agar by HIFU histotripsy. | Histotripsy uses high-intensity focused ultrasound pulses at low duty cycle to generate energetic bubble clouds inside tissue to fractionate a region. As a potential tumor treatment modality, this cavitation-based non-invasive technique has the advantages of easy monitoring and sharp borders. Aiming at therapy efficien... | ['Agar', 'Calibration', 'Elasticity', 'Equipment Design', 'High-Intensity Focused Ultrasound Ablation', 'Models, Theoretical', 'Phantoms, Imaging', 'Pressure', 'Sonication', 'Time Factors', 'Transducers'] | 23,339,995 | [['D09.698.360.041'], ['E05.978.155'], ['G01.374.590'], ['E05.320'], ['E02.565.280.945.399', 'E04.014.380'], ['E05.599'], ['E07.671'], ['G01.374.715'], ['E05.848'], ['G01.910.857'], ['E07.305.812']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Amiloride-sensitive trypsinization of apical sodium channels. Analysis of hormonal regulation of sodium transport in toad bladder. | Incubation of the mucosal surface of the toad urinary bladder with trypsin (1 mg/ml) irreversibly decreased the short-circuit current to 50% of the initial value. This decrease was accompanied by a proportionate decrease in apical Na permeability, estimated from the change in amiloride-sensitive resistance in depolariz... | ['Aldosterone', 'Amiloride', 'Animals', 'Biological Transport', 'Bufo marinus', 'Ion Channels', 'Pyrazines', 'Pyruvates', 'Stimulation, Chemical', 'Trypsin', 'Urinary Bladder', 'Vasopressins'] | 6,308,125 | [['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['D03.383.679.149'], ['B01.050'], ['G03.143'], ['B01.050.150.900.090.180.210.580'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['D03.383.679'], ['D02.241.755.812'], ['G07.690.773.996'], ['D08.811.277.656.300.760.895', 'D08.811.277.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence of dry eye in the normal population in Jeddah, Saudi Arabia. | PURPOSE: To estimate the prevalence of dry eye disease in the normal non-complaining population.METHODS: Prospective systematic random sampling study of 251 subjects who accompanied patients with appointments to the eye clinic. Interviewers administered a dry eye symptoms and risk factor questionnaire. Tear film break ... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Child', 'Dry Eye Syndromes', 'Female', 'Fluorophotometry', 'Humans', 'Male', 'Middle Aged', 'Prevalence', 'Prospective Studies', 'Risk Factors', 'Saudi Arabia', 'Sex Distribution', 'Surveys and Questionnaires', 'Tears', 'Young Adult'] | 19,929,667 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.406'], ['C11.496.260'], ['E01.370.380.255', 'E05.196.712.516.600.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.8... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Hyperspectral image measurements of skin hemoglobin compared with transcutaneous PO2 measurements. | BACKGROUND: Objective measurements of skin blood flow would have predictive value in assessing the potential for wound healing. In this study, we evaluated the relationship between transcutaneous PO(2) (tcPO(2)) measurements and hyperspectral reflectance spectroscopy measurements of oxygenated hemoglobin (OxyHgb), deox... | ['Blood Flow Velocity', 'Blood Gas Monitoring, Transcutaneous', 'Female', 'Hemoglobins', 'Humans', 'Male', 'Oxygen', 'Peripheral Vascular Diseases', 'Predictive Value of Tests', 'Reproducibility of Results', 'Skin', 'Spectrum Analysis'] | 22,520,392 | [['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.225.124.100.100.600.100', 'E01.370.370.380.600.100', 'E01.370.386.700.100.600.100', 'E05.200.124.100.100.600.100'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.185.550', 'D01.362.670'], ['C14.907.617'], ['E... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Axillary-subclavian vein thrombosis following combination chemotherapy and radiation therapy in lymphoma. | Four patients with deep venous thrombosis of the upper extremity (DVTUE) following combined modality therapy (mantle radiotherapy and chemotherapy) for either Hodgkin's disease or non-Hodgkin's lymphoma were seen at Stanford University Medical Center between March 1980 and April 1984. A total of 235 patients had receiv... | ['Adolescent', 'Adult', 'Antineoplastic Combined Chemotherapy Protocols', 'Axillary Vein', 'Combined Modality Therapy', 'Female', 'Hodgkin Disease', 'Humans', 'Lymphoma', 'Male', 'Radiotherapy', 'Subclavian Vein', 'Thrombosis'] | 3,957,737 | [['M01.060.057'], ['M01.060.116'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['A07.015.908.077'], ['E02.186'], ['C04.557.386.355', 'C15.604.515.569.355', 'C20.683.515.761.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386', 'C15.604.515.569', 'C20.683.515.761'], ['E02.815'], ['A07.01... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Intra-axial tumors of the cervicomedullary junction. | The authors present their experience with the operative management of 20 intra-axial tumors of the cervicomedullary junction. There were two distinct modes of clinical presentation: lower cranial nerve dysfunction and spinal cord dysfunction. Both groups of patients had indolent courses: in 75% of the patients the symp... | ['Adolescent', 'Adult', 'Brain Neoplasms', 'Child', 'Child, Preschool', 'Cranial Nerves', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Medulla Oblongata', 'Middle Aged', 'Prognosis', 'Spinal Cord', 'Spinal Cord Neoplasms', 'Ultrasonography'] | 3,309,202 | [['M01.060.057'], ['M01.060.116'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['M01.060.406'], ['M01.060.406.448'], ['A08.800.800.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A08.186.211.132.810.591.500'], ['M01.060.116.630'], ['E01.789'], ['A08.186.854'], ['C04... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Melatonin influences gonadotropin II secretion in the Atlantic croaker (Micropogonias undulatus). | The role of melatonin in the control of gonadotropin II (GtH II) secretion was investigated in Atlantic croaker (Micropogonias undulatus) during different phases of the day-night cycle and seasonal reproductive cycle. Intraperitoneal injection of melatonin during the late-light phase of the day-night cycle elicited a s... | ['Adaptation, Physiological', 'Animals', 'Circadian Rhythm', 'Dose-Response Relationship, Drug', 'Gonadotropin-Releasing Hormone', 'Gonadotropins, Pituitary', 'Injections, Intraperitoneal', 'Melatonin', 'Perciformes', 'Pituitary Gland', 'Time Factors'] | 8,930,614 | [['G07.025', 'G16.012.500'], ['B01.050'], ['G07.180.562.190'], ['G07.690.773.875', 'G07.690.936.500'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['D06.472.699.322.576', 'D06.472.699.631.525.343', 'D12.644.548.691.525.343'], ['E02... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Timolol maleate: side effects on healthy nonglaucomatous volunteers. | As the number of military pilots over the age of 40 increases, open-angle glaucoma becomes an important aeromedical problem. Epinephrine ophthalmic solution is the only antiglaucomatotic agent in use among flying personnel. Timolol maleate, a new antiglaucomatotic agent, is a nonselective beta-blocker. This drug has a ... | ['Adrenergic beta-Antagonists', 'Adult', 'Aerospace Medicine', 'Glaucoma', 'Heart Rate', 'Humans', 'Intraocular Pressure', 'Israel', 'Male', 'Military Medicine', 'Propanolamines', 'Time Factors', 'Timolol'] | 6,133,515 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116'], ['H02.403.029'], ['C11.525.381'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['Z01.252.245.500.375'], ['H02.403.500'], ['D02.033.100.624', 'D02.033.755.624', 'D02.092.063.624'... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 |
Damar Batu as a novel matrix former for the transdermal drug delivery: in vitro evaluation. | PURPOSE: Damar Batu (DB) is a novel film-forming biomaterial obtained from Shorea species, evaluated in this study for its potential application in transdermal drug delivery system.METHODS: DB was characterized initially in terms of acid value, softening point, molecular weight (M(w)), polydispersity index (M(w)/M(n)),... | ['Administration, Cutaneous', 'Animals', 'Chromatography, Thin Layer', 'Diffusion Chambers, Culture', 'Drug Carriers', 'Drug Delivery Systems', 'Drug Stability', 'Irritants', 'Membranes, Artificial', 'Polymers', 'Rats', 'Rats, Wistar', 'Resins, Plant', 'Skin Absorption', 'Solubility', 'Spectrophotometry, Infrared', 'Sp... | 19,555,240 | [['E02.319.267.120.060'], ['B01.050'], ['E05.196.181.400.537'], ['E07.241'], ['D26.255.260', 'E02.319.300.380'], ['E02.319.300'], ['E05.916.330'], ['D27.720.400', 'D27.888.569.300'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['B01.050.150.900.649.313.992.635.505.700']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effect of different beverages on the color stability and degree of conversion of nano and microhybrid composites. | This study sought to evaluate the effects of different staining solutions on the colour stability of nanocomposites compared with microhybrid resin and to evaluate the degree of conversion of these two materials. Two different shades of two different composites were cured in polytetraflouroethylene disk rings. Coffee, ... | ['Beverages', 'Carbonated Beverages', 'Coffee', 'Color', 'Composite Resins', 'Dental Materials', 'Humans', 'Materials Testing', 'Nanocomposites', 'Polymerization', 'Spectrophotometry', 'Surface Properties', 'Tea', 'Temperature', 'Time Factors', 'Water'] | 23,538,770 | [['G07.203.100', 'J02.200'], ['G07.203.100.300', 'J02.200.300'], ['D20.215.784.249', 'G07.203.100.325', 'J02.200.325'], ['G01.590.540.199'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['D25.339', 'D27.720.102.339', 'J01.637.051.339'], ['B... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Characterization of solubilized benzodiazepine and muscimol binding sites from rat brain. | Binding sites for muscimol and flunitrazepam were solubilized and their properties studied by ultrafiltration, isoelectro-focusing and cation-exchange chromatography methods. The heterogenity of binding sites for flunitrazepam was demonstrated in the ultrafiltration experiments: the binding sites with a molecular weigh... | ['Animals', 'Brain', 'Chromatography, Ion Exchange', 'Flunitrazepam', 'In Vitro Techniques', 'Isoelectric Focusing', 'Rats', 'Receptors, Cell Surface', 'Receptors, GABA-A', 'Ultrafiltration', 'gamma-Aminobutyric Acid'] | 6,296,717 | [['B01.050'], ['A08.186.211'], ['E05.196.181.400.383'], ['D03.633.100.079.080.070.320'], ['E05.481'], ['E05.196.401.663', 'E05.301.300.663'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.543.750'], ['D12.776.157.530.400.175.562', 'D12.776.157.530.400.400.100.100', 'D12.776.543.550.450.175.562', 'D12.776.543.5... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Solution, solid phase and computational structures of apicidin and its backbone-reduced analogs. | The recently isolated broad-spectrum antiparasitic apicidin (1) is one of the few naturally occurring cyclic tetrapeptides (CTP). Depending on the solvent, the backbone of 1 exhibits two gamma-turns (in CH(2)Cl(2)) or a beta-turn (in DMSO), differing solely in the rotation of the plane of one of the amide bonds. In the... | ['Computer Simulation', 'Crystallography, X-Ray', 'Hydrogen Bonding', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Molecular Structure', 'Oligopeptides', 'Peptides, Cyclic', 'Protein Conformation'] | 16,342,331 | [['L01.224.160'], ['E05.196.309.742.225'], ['G02.282'], ['E05.196.867.519'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['D12.644.456'], ['D04.345.566', 'D12.644.641'], ['G02.111.570.820.709']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Hematologic repercussions of physical exercise in the mountains]. | Marked decrease of serum ferritin was found in 28 cadets of the General Military Academy after a 15-day high-mountain drill period during which they practised ski 5 hours a day. No significant changes were found in serum iron, total iron binding capacity, vitamin B 12 and folates. Slight differences found in haemoglobi... | ['Adaptation, Physiological', 'Adult', 'Altitude', 'Blood Cell Count', 'Blood Proteins', 'Exercise', 'Ferritins', 'Hemoglobins', 'Humans', 'Iron', 'Male', 'Military Personnel', 'Mountaineering', 'Skiing', 'Vitamins'] | 2,772,779 | [['G07.025', 'G16.012.500'], ['M01.060.116'], ['G16.500.275.058', 'N06.230.058'], ['E01.370.225.500.195.107', 'E01.370.225.625.107', 'E05.200.500.195.107', 'E05.200.625.107', 'E05.242.195.107', 'G04.140.107', 'G09.188.105'], ['D12.776.124'], ['G11.427.410.698.277', 'I03.350'], ['D12.776.157.427.249', 'D12.776.556.579.2... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Supercoiling in a Protein Increases its Stability. | The supercoiling motif is the most complex type of nontrivial topology found in proteins with at least one disulfide bond and, to the best of our knowledge, it has not been studied before. We show that a protein from extremophilic species with such a motif can fold; however, the supercoiling changes a smooth landscape ... | ['Kinetics', 'Models, Chemical', 'Models, Molecular', 'Protein Conformation', 'Protein Folding', 'Proteins', 'Thermodynamics'] | 31,697,559 | [['G01.374.661', 'G02.111.490'], ['E05.599.495'], ['E05.599.595'], ['G02.111.570.820.709'], ['G01.154.651', 'G02.111.688'], ['D12.776'], ['G01.906']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neurobehavioral deficits, diseases, and associated costs of exposure to endocrine-disrupting chemicals in the European Union. | CONTEXT: Epidemiological studies and animal models demonstrate that endocrine-disrupting chemicals (EDCs) contribute to cognitive deficits and neurodevelopmental disabilities.OBJECTIVE: The objective was to estimate neurodevelopmental disability and associated costs that can be reasonably attributed to EDC exposure in ... | ['Adolescent', 'Adult', 'Attention Deficit Disorder with Hyperactivity', 'Autistic Disorder', 'Child', 'Child, Preschool', 'Cost of Illness', 'Endocrine Disruptors', 'Endocrine System Diseases', 'Environmental Exposure', 'Europe', 'European Union', 'Female', 'Humans', 'Intellectual Disability', 'Male', 'Mental Disorder... | 25,742,515 | [['M01.060.057'], ['M01.060.116'], ['F03.625.094.150'], ['F03.625.164.113.500'], ['M01.060.406'], ['M01.060.406.448'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['D27.505.696.353', 'D27.888.141'], ['C19'], ['N06.850.460.350'], ['Z01.542'], ['I01.615.500.475'], ['B01.050.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Cytokines and chemokines in serum and urine as early predictors to identify septic patients on intensive care unit. | The aim of this prospective cohort study was to address the feasibility of measuring cytokines in serum and urine as early predictor tests for the identification of septic Intensive Care Unit (ICU) patients. The study group consisted of 10 septic and 5 non-septic patients at the onset of sepsis according to modified de... | ['Adult', 'Aged', 'Calcitonin', 'Calcitonin Gene-Related Peptide', 'Chemokines', 'Cohort Studies', 'Cytokines', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Intensive Care Units', 'Interleukin-18', 'Male', 'Middle Aged', 'Protein Precursors', 'RNA, Messenger', 'Sepsis', 'Time Factors'] | 12,964,035 | [['M01.060.116'], ['M01.060.116.100'], ['D06.472.699.150', 'D06.472.931.052', 'D12.644.400.095', 'D12.644.548.150', 'D12.776.631.650.095'], ['D12.644.400.097', 'D12.776.631.650.097'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['E05.318.372.500.750', 'N05.715.360.33... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Rapid kinetic analyses of the Na+/K(+)-ATPase distinguish among different criteria for conformational change. | The Na+/K(+)-ATPase couples the hydrolysis of ATP to the transport of Na+ and K+ via a phosphorylated intermediate and conformational changes. In order to identify these conformational changes, we have probed the sequence of steps from EP(3Na+ in) to EP + 3Na+ out with three fluorescent probes (IAF: 5-iodoacetamidofluo... | ['Calcium', 'Kinetics', 'Magnesium', 'Maleimides', 'Manganese', 'Protein Conformation', 'Sodium-Potassium-Exchanging ATPase'] | 8,395,217 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G01.374.661', 'G02.111.490'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['D02.241.081.337.502.524', 'D02.478.440', 'D03.383.129.578.399'], ['D01.268.556.484', 'D01.268.956.374', 'D01.552.544.484'], ['G02.111.570.820.709'], ['D08.811.277.040.025.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of levofloxacin and cefotaxime combined with ofloxacin for ICU patients with community-acquired pneumonia who do not require vasopressors. | STUDY OBJECTIVES: To evaluate the efficacy and tolerability of levofloxacin (L) as monotherapy in patients with severe community-acquired pneumonia (CAP) in comparison with therapy using a combination of cefotaxime (C) plus ofloxacin (O).DESIGN: Prospective, randomized 1:1, comparative, open, parallel-group study.SETTI... | ['Adult', 'Aged', 'Anti-Bacterial Agents', 'Cefotaxime', 'Chi-Square Distribution', 'Community-Acquired Infections', 'Drug Therapy, Combination', 'Female', 'Humans', 'Infusions, Intravenous', 'Intensive Care Units', 'Levofloxacin', 'Male', 'Middle Aged', 'Ofloxacin', 'Pneumonia, Bacterial', 'Prospective Studies', 'Trea... | 16,002,932 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.085'], ['D02.065.589.099.249.190.190', 'D02.886.665.074.190.190', 'D03.633.100.300.249.190.190'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C01.234'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characteristics, management and medical costs of patients with depressive disorders admitted in primary and specialised care centres in Spain between 2011 and 2016. | More than 10% of the population will suffer from a depressive disorder during their lifetime, which represents a substantial economic and social burden for healthcare systems and societies. Nonetheless, studies suggest that an important percentage of patients receive inadequate treatment. This study aimed to evaluate t... | ['Depressive Disorder', 'Female', 'Health Care Costs', 'Humans', 'Male', 'Medicine', 'Middle Aged', 'Primary Health Care', 'Retrospective Studies', 'Spain'] | 32,023,308 | [['F03.600.300'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403'], ['M01.060.116.630'], ['N04.590.233.727'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.4... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Examining the association between social cognition and functioning in individuals at ultra-high risk for psychosis. | OBJECTIVE: Social and role functioning are compromised for the majority of individuals at ultra-high risk of psychosis, and it is important to identify factors that contribute to this functional decline. This study aimed to investigate social cognitive abilities, which have previously been linked to functioning in schi... | ['Adult', 'Facial Expression', 'Female', 'Humans', 'Internal-External Control', 'Male', 'Psychotic Disorders', 'Risk', 'Social Perception', 'Theory of Mind', 'Young Adult'] | 26,698,819 | [['M01.060.116'], ['E01.370.600.225', 'F01.145.209.530.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['F03.700.675'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600.800'], ['F02.463.593.752'], ['F02.463.689', 'F02.739.897'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dysnomia in dementia and in stroke patients: different underlying cognitive deficits. | The performance of 11 Alzheimer's (DAT) and 8 anomic aphasic stroke patients is contrasted with that of 32 normal elderly subjects on both the Boston Naming Test (BNT) and the Controlled Oral Word Association Test (COW), a letter-category verbal-fluency test. While both tests require phonological processing, only the B... | ['Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Anomia', 'Brain Damage, Chronic', 'Cerebrovascular Disorders', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Word Association Tests'] | 2,211,980 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['C10.597.606.150.500.090', 'C23.888.592.604.150.500.090'], ['C10.228.140.140'], ['C10.228.140.300', 'C14.907.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Elucidating the mechanism of Cr(VI) formation upon the interaction with metal oxides during coal oxy-fuel combustion. | The thermodynamics underpinning the interaction of Cr-bearing species with basic metal oxides, i.e. K2O, Fe2O3, MgO and CaO, during the air and oxy-fuel combustion of coal have been examined. The synchrotron-based X-ray adsorption near-edge spectroscopy (XANES) was used for Cr speciation. For the oxides tested, Cr(VI) ... | ['Chromium', 'Coal', 'Coal Ash', 'Environmental Pollutants', 'Oxides', 'Thermodynamics'] | 23,969,010 | [['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['D20.345.108', 'N06.230.132.258.108'], ['D20.633.110'], ['D27.888.284'], ['D01.248.497.158.685', 'D01.650.550'], ['G01.906']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The inhibiting effect of a plasma globulin on arterial thrombus formation, (as compared to dipyridamole). | The inhibiting effect on arterial white thrombus formation of a globulin prepared from beef plasma has been compared to dipyridamole in white Wistar rats. It was demonstrated that the globulin fraction had a greater effect in inhibiting thrombus formation as judged by the lag time [t(l)], the maximal thrombus value [m(... | ['Animals', 'Blood Coagulation', 'Dipyridamole', 'Male', 'Mesenteric Arteries', 'Rats', 'Serum Globulins', 'Time Factors'] | 725,841 | [['B01.050'], ['G09.188.390.150'], ['D03.383.742.175'], ['A07.015.114.565'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.124.790', 'D12.776.377.715'], ['G01.910.857']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reducing pharmacy wait time to promote customer service: a follow-up study. | PURPOSE: The present study had 3 objectives: (1) to evaluate the effects of 2 different interventions (feedback regarding customer satisfaction with wait time and combined feedback and goal setting) on wait time in a hospital outpatient pharmacy; (2) to assess the extent to which the previously applied interventions ma... | ['Adult', 'Feedback', 'Female', 'Follow-Up Studies', 'Goals', 'Humans', 'Male', 'Middle Aged', 'Patient Satisfaction', 'Pharmaceutical Services', 'Time Factors', 'Waiting Lists'] | 25,539,487 | [['M01.060.116'], ['L01.906.394.211'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['F01.658.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.6... | ['Named Groups [M]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Development of quantitative molecular clinical end points for siRNA clinical trials. | RNA interference (RNAi) is an evolutionarily conserved mechanism that results in specific gene inhibition at the mRNA level. The discovery that short interfering RNAs (siRNAs) are selective, potent, and can largely avoid immune surveillance has resulted in keen interest to develop these inhibitors as therapeutics. A si... | ['Bony Callus', 'Cells, Cultured', 'Clinical Trials as Topic', 'Humans', 'Keratin-6', 'Keratinocytes', 'Pachyonychia Congenita', 'Polymorphism, Single Nucleotide', 'RNA Interference', 'RNA, Messenger', 'RNA, Small Interfering', 'Skin'] | 21,191,405 | [['A10.165.265.200'], ['A11.251'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.593.450.600.600', 'D12.776.220.475.450.600.600', 'D12.776.860.607.650.600'], ['A11.409.500', 'A11.436.397'], ['C16.131.077.350.856', 'C16.131.8... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Prolonged persistence of a large pericardial effusion and hemodynamic evidence of cardiac tamponade during treatment of myxedema. | We describe clinical, echocardiographic, and catheterization findings that were present initially and during therapy in a myxedematous patient with a large pericardial effusion and tamponade. Treatment with thyroxine resulted in a marked improvement of most of the clinical features of hypothyroidism and some improvemen... | ['Aged', 'Cardiac Tamponade', 'Drainage', 'Female', 'Humans', 'Hypothyroidism', 'Myxedema', 'Pericardial Effusion', 'Thyroxine'] | 7,127,923 | [['M01.060.116.100'], ['C14.280.155'], ['E02.309', 'E04.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.482'], ['C17.300.550.590', 'C19.874.482.638'], ['C14.280.695'], ['D06.472.931.812', 'D12.125.072.050.767']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of a parietal cell vagotomy and truncal vagotomy with and without drainage on duodenal ulcers in the rat. | The gastric secretagogues, pentagastrin and carbachol, produced a 100% incidence of duodenal ulcers. Truncal vagotomy (TV) and parietal cell vagotomy (PCV) prevented these experimental ulcers in the early post-operative period. At 3 weeks TV rats showed a decrease in weight gain, gross gastric distension and the infusi... | ['Animals', 'Carbachol', 'Drainage', 'Duodenal Ulcer', 'Male', 'Pentagastrin', 'Postoperative Complications', 'Rats', 'Stomach Ulcer', 'Vagotomy'] | 7,250,555 | [['B01.050'], ['D02.092.877.883.333.115', 'D02.675.276.232.115'], ['E02.309', 'E04.237'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['D06.472.317.413.593', 'D12.644.456.716'], ['C23.550.767'], ['B01.050.150.900.649.313.992.635.505.700'], ['C06.405.469.275.800.849', 'C06.405.748.586.849'], ['E04.525.210.105.60... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Free phenols in maize pith and their relationship with resistance to Sesamia nonagrioides (Lepidoptera: Noctuidae) attack. | The stem borer Sesamia nonagrioides (Lef?bvre) is the most important insect pest of maize, Zea mays L., in northwestern Spain. Among the metabolites present in maize, phenolic compounds could play an important role in resistance. The objective of this work was to determine whether a relationship between phenols and the... | ['Animals', 'Moths', 'Phenols', 'Plant Stems', 'Zea mays'] | 16,156,590 | [['B01.050'], ['B01.050.500.131.617.720.500.500.937.650'], ['D02.455.426.559.389.657'], ['A18.024.937'], ['B01.650.940.800.575.912.250.822.966']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Precocious hypothyroidism mechanisms after radioiodine treatment in Graves' disease. | OBJECTIVE: Hypothyroidism can occur after radioiodine treatment for Graves' disease. It may happen precociously and transiently in the first year after treatment. The purpose of this study was to understand the mechanisms responsible for precocious hypothyroidism.METHODS: 36 patients treated for Graves disease by radio... | ['Female', 'Graves Disease', 'Humans', 'Hypothyroidism', 'Iodine Radioisotopes', 'Male', 'Middle Aged', 'Prospective Studies', 'Time Factors'] | 21,036,005 | [['C11.675.349.500', 'C19.874.283.605', 'C19.874.397.370', 'C20.111.555'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.482'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A possible role for oxytocin in the response to a psychological stressor. | Recent evidence suggests that oxytocin (OXT) potentiates corticotropin releasing factor-induced secretion of ACTH. The present study was therefore designed to investigate the possible role of oxytocin in the response to predictable and unpredictable novelty stress. The results clearly demonstrate that oxytocin produced... | ['11-Hydroxycorticosteroids', 'Animals', 'Female', 'Oxytocin', 'Pituitary-Adrenal System', 'Rats', 'Rats, Inbred Strains', 'Stress, Psychological'] | 3,749,216 | [['D06.472.040.585.353'], ['B01.050'], ['D06.472.699.631.692.433', 'D12.644.548.691.692.433'], ['A06.300.691'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['F01.145.126.990', 'F02.830.900']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dynamics and biodiversity of populations of lactic acid bacteria and acetic acid bacteria involved in spontaneous heap fermentation of cocoa beans in Ghana. | The Ghanaian cocoa bean heap fermentation process was studied through a multiphasic approach, encompassing both microbiological and metabolite target analyses. A culture-dependent (plating and incubation, followed by repetitive-sequence-based PCR analyses of picked-up colonies) and culture-independent (denaturing gradi... | ['Acetic Acid', 'Acetobacter', 'Biodiversity', 'Bioreactors', 'Cacao', 'Carbohydrate Metabolism', 'Citric Acid', 'Cluster Analysis', 'Colony Count, Microbial', 'DNA Fingerprinting', 'DNA, Bacterial', 'DNA, Ribosomal', 'Ethanol', 'Fermentation', 'Fructose', 'Gram-Positive Bacteria', 'Lactic Acid', 'Lactobacillus', 'Mann... | 17,277,227 | [['D02.241.081.018.165', 'D10.251.400.045.500'], ['B03.440.400.425.100.100', 'B03.660.050.755.050.010'], ['G16.500.275.157.049', 'N06.230.124.049'], ['E07.115', 'J01.897.120.115'], ['B01.650.940.800.575.912.250.859.821.500.164'], ['G02.111.158', 'G03.191'], ['D02.241.081.901.434.249'], ['E05.318.740.250', 'N05.715.360.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
Influence of neonatal treatment with porcine insulin (hormonal imprinting) on the receptor binding of insulins of porcine, rat and human origin. | A single neonatal insulin treatment in the male rat decreases, whereas in the female rat it increases, the number of insulin receptors detected at the age of one month. No difference could be observed in affinity. The extent of the binding of rat, porcine and human insulin is different (the binding of human insulin is ... | ['Animals', 'Animals, Newborn', 'Female', 'Insulin', 'Male', 'Rats', 'Rats, Inbred Strains', 'Receptor, Insulin'] | 3,074,622 | [['B01.050'], ['B01.050.050.282'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D08.811.913.696.620.682.725.400.200', 'D12.776.543.750.630.484', 'D12.776.543.750.750.580.300']] | ['Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Computer-assisted information processing in nephrology exemplified by the Nephrology-Dialysis Data System]. | The data system nephrology/dialysis (DSND) may improve the documentation and information processes used in chronic hemodialysis. DNSD is efficient if the data input is done carefully. It is possible to display large numbers of laboratory and dialysis data arranged alpha-numerically or graphically. Data over a period of... | ['Germany', 'Humans', 'Information Systems', 'Kidney Diseases', 'Medical Records', 'Quality Assurance, Health Care', 'Renal Dialysis'] | 2,267,864 | [['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313.500.750.300'], ['C12.777.419', 'C13.351.968.419'], ['E05.318.308.940.968', 'N04.452.859.564', 'N05.715.360.300.715.500', 'N06.850.520.308.940.968'], ['N04.761.700', 'N05.700'], ['E02.870.300', 'E02.912.800']] | ['Geographicals [Z]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Perineural spread of rhinocerebral mucormycosis. | An unusual pathway of local spread of rhinocerebral mucormycosis is presented with MR and pathologic correlation. Perineural extension, proved with pathology, followed the trigeminal nerve to the pons. Enhancement of the nerve was seen on MR. | ['Aged', 'Biopsy', 'Brain', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Meningitis, Fungal', 'Mucormycosis', 'Opportunistic Infections', 'Paranasal Sinuses', 'Pons', 'Sinusitis', 'Tomography, X-Ray Computed', 'Trigeminal Nerve'] | 8,770,260 | [['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C01.150.703.181.500', 'C01.207.198.500', 'C10.228.228.198.500'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Acute blood pressure elevations]. | Blood pressure (BP) elevations may correspond to different clinical situations. Hypertensives emergencies are situations that require immediate reduction in BP because of acute or rapidly progressing target organ damage: accelerated malignant hypertension, hypertensive encephalopathy, acute myocardial infarction, acute... | ['Acute Disease', 'Blood Pressure', 'Blood Pressure Determination', 'Diagnosis, Differential', 'Drug-Related Side Effects and Adverse Reactions', 'Eclampsia', 'Female', 'Humans', 'Hypertension', 'Hypertrophy, Left Ventricular', 'Male', 'Myocardial Infarction', 'Pheochromocytoma', 'Pregnancy', 'Stroke'] | 11,190,294 | [['C23.550.291.125'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140', 'E01.370.600.100'], ['E01.171'], ['C25.100'], ['C13.703.395.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C14.280.195.400', 'C23.300.775.250.400'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.7... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A complex signaling network involving protein kinase CK2 is required for hepatitis C virus core protein-mediated modulation of the iron-regulatory hepcidin gene expression. | Hepatitis C virus (HCV) infection is associated with hepatic iron overload and elevated serum iron that correlate to poor antiviral responses. Hepcidin (HAMP), a 25-aa cysteine-rich liver-specific peptide, controls iron homeostasis. Its expression is up-regulated in inflammation and iron excess. HCV-mediated hepcidin r... | ['Casein Kinase II', 'Cell Line, Tumor', 'Cell Nucleus', 'Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Viral', 'Gene Silencing', 'Hep G2 Cells', 'Hepacivirus', 'Hepcidins', 'Homeostasis', 'Humans', 'Iron', 'Promoter Regions, Genetic', 'RNA Interference', 'STAT3 Transcription Factor', 'Signal T... | 24,718,935 | [['D08.811.913.696.620.682.700.140.600', 'D12.776.476.150.600'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G05.308.320'], ['G05.308.385'], ['G05.308.203.374'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B04.450.380', 'B04.820.578.344.475'], ['D12.776.494.249', 'D12... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Calling into question the NHS approach to patient safety. | In a two-part column John Tingle discusses the Health Foundation's recent report on changing the NHS approach to patient safety. Part one looks at the first part of the report: the case for change. | ['Humans', 'Patient Safety', 'State Medicine', 'United Kingdom'] | 26,653,523 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.135.060.075.399'], ['N03.349.550.902', 'N03.858'], ['Z01.542.363']] | ['Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Human papillomavirus (HPV) type 11 recombinant virus-like particles induce the formation of neutralizing antibodies and detect HPV-specific antibodies in human sera. | Recombinant human papillomavirus type 11 (HPV-11) virus-like particles (VLPs) were tested for their ability to induce the formation of neutralizing antibodies, and were also tested for serodiagnostic capabilities in an ELISA in comparison with HPV-11 whole virions. VLPs, purified by CsCl density gradient centrifugation... | ['Animals', 'Antibodies, Viral', 'Condylomata Acuminata', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Mice', 'Mice, Nude', 'Neutralization Tests', 'Papillomaviridae', 'Papillomavirus Infections', 'Recombinant Proteins', 'Tumor Virus Infections', 'Viral Proteins', 'Virion'] | 8,046,412 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['C01.221.812.640.220', 'C01.778.640.220', 'C01.925.256.650.810.217', 'C01.925.813.220', 'C01.925.825.810.110', 'C01.925.928.914.217', 'C17.800.838.790.810.110'], ['E05.478.566.350.170', 'E05.478.566.380.360', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Epidemic occurrence of respiratory tract infections due to chlamydia]. | An analysis included 92 children aged between 3 and 7 years, 88 children aged between 3 months and 17 years and 29 their parents with diagnosed chlamydial respiratory infections. Incidence of respiratory infections in the studies pre-school children was 53.2% while in family environment -87.5% in children, and 68.9% in... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Chlamydia Infections', 'Disease Outbreaks', 'Family', 'Humans', 'Incidence', 'Infant', 'Respiratory Tract Infections'] | 8,415,261 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C12.294.668.281.301', 'C13.351.500.711.281.301'], ['N06.850.290'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Anti-aquaporin-4 antibody-positive optic neuritis treated with double-filtration plasmapheresis. | PURPOSE: The anti-aquaporin-4 (AQP4) antibody was recently reported to be associated with neuromyelitis optica (NMO). Optic nerve involvements in many NMO cases are bilateral and the prognosis is poor. However, it has been suggested that plasma exchange is effective for those patients when steroid pulse therapy is inef... | ['Aquaporin 4', 'Autoantibodies', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Neuromyelitis Optica', 'Plasmapheresis', 'Spinal Cord', 'Young Adult'] | 20,698,801 | [['D12.776.157.530.400.500.040.468', 'D12.776.543.550.450.730.040.468', 'D12.776.543.585.400.730.040.577'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C10.114.375.600.500', 'C10.114.375.800', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A phase II study on continuous infusional paclitaxel and 5-Fu as first-line chemotherapy for patients with advanced esophageal cancer. | OBJECTIVE: This study was performed to evaluated the efficacy and safety of continuous infusional paclitaxel and 5-Fu as first-line chemotherapy in patients with advanced esophageal squamous cell cancer (ESCC).METHODS: A total of 22 patients with advanced esophageal squamous cell cancer with no indications for surgery ... | ['Adolescent', 'Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma, Squamous Cell', 'Esophageal Neoplasms', 'Female', 'Fluorouracil', 'Follow-Up Studies', 'Humans', 'Infusions, Intravenous', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Paclitaxel', 'Prognosis', 'Survival Rate', 'Young Adult'] | 23,317,222 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['D03.383.742.698.875.404'], ['E05.318.372.500.750.249',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ethical issues in community-based participatory research: balancing rigorous research with community participation in community intervention studies. | PROBLEM: Concerns have been raised that community participation might compromise scientific rigor in community-based participatory research (CBPR).PURPOSE: The purpose of this paper is to identify potential sources of tension between the values of scientific rigor and community participation in CBPR.KEY POINTS: CBPR li... | ['Community Participation', 'Community-Based Participatory Research', 'Humans', 'Research Design', 'Resource Allocation'] | 20,208,234 | [['N02.421.143.212', 'N03.540.245.360'], ['H01.770.644.193', 'N05.425.104'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581.500', 'H01.770.644.728'], ['I01.261.750']] | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Sequential injection extraction based on restricted access material for determination of furosemide in serum. | Restricted access material (RAM) column containing 25 microm C18 alkyl-diol support was integrated into the sequential injection analysis (SIA) manifold and the SIA-RAM system was tested for direct determination of furosemide in serum. LiChrospher ADS column based on restricted access material is proposed to direct inj... | ['Adsorption', 'Calibration', 'Chromatography, High Pressure Liquid', 'Diuretics', 'Furosemide', 'Hydrogen-Ion Concentration', 'Reference Standards', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Spectrometry, Fluorescence'] | 16,130,720 | [['G01.030', 'G02.020'], ['E05.978.155'], ['E05.196.181.400.300'], ['D27.505.696.560.500'], ['D02.065.884.725.300', 'D02.092.146.807.300', 'D02.886.590.700.725.300'], ['G02.300'], ['E05.978.808'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Quantification of activated carbon contents in soils and sediments using chemothermal and wet oxidation methods. | Activated carbon (AC) strongly sorbs organic pollutants and can be used for remediation of soils and sediments. A method for AC quantification is essential to monitor AC (re)distribution. Since AC is black carbon (BC), two methods for BC quantification were tested for AC mixed in different soils and sediments: i) chemo... | ['Adsorption', 'Charcoal', 'Chemistry Techniques, Analytical', 'Environmental Restoration and Remediation', 'Geologic Sediments', 'Hot Temperature', 'Oxidation-Reduction', 'Soil'] | 19,683,375 | [['G01.030', 'G02.020'], ['D01.268.150.150'], ['E05.196'], ['N06.230.080.600', 'N06.850.460.375'], ['G01.311.330', 'G16.500.320'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G02.700', 'G03.295.531'], ['D20.721', 'G01.311.820... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparative Analysis of Gene Expression Profiles of Human Dental Fluorosis and Kashin-Beck Disease. | To explore the pathologies of Kashin-Beck disease (KBD) and KBD accompanied with dental fluorosis (DF), we conducted a comparative analysis of gene expression profiles. 12 subjects were recruited, including 4 KBD patients, 4 patients with KBD and DF and 4 healthy subjects. Genome-wide expression profiles from their per... | ['Case-Control Studies', 'Fluorosis, Dental', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Humans', 'Kashin-Beck Disease', 'Reproducibility of Results', 'Transcriptome'] | 29,317,700 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C07.793.330'], ['E05.393.332'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.099.708.534'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['G02.111.873.750', 'G05.297.700.750'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of sevoflurane anaesthesia on renal function. | The effects of sevoflurane on renal function were investigated in 34 patients anaesthetized with sevoflurane. Based on preoperative serum creatinine levels, patients were classified into three groups: Group 1 (n = 25) had normal renal function (serum creatinine < 1.0 mg/dl); Group 2 (n = 5) had slight renal dysfunction... | ['Adult', 'Aged', 'Anesthetics, Inhalation', 'Blood Urea Nitrogen', 'Creatinine', 'Ethers', 'Female', 'Humans', 'Kidney', 'Male', 'Methyl Ethers', 'Middle Aged', 'Postoperative Period', 'Renal Insufficiency', 'Sevoflurane'] | 9,100,163 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.277.100.035.060', 'D27.505.954.427.210.100.035.060'], ['E01.370.225.124.100.115', 'E01.370.390.400.100', 'E05.200.124.100.115'], ['D03.383.129.308.207'], ['D02.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['D02.355.601'], ['M01.060.116.630... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The core domain of retrotransposon integrase in Hordeum: predicted structure and evolution. | Propagation of long terminal repeat (LTR)-bearing retrotransposons and retroviruses requires integrase (IN, EC 2.7.7.-), encoded by the retroelements themselves, which mediates the insertion of cDNA copies back into the genome. An active retrotransposon family, BARE-1, comprises approximately 7% of the barley (Hordeum ... | ['Amino Acid Sequence', 'Base Sequence', 'Cloning, Molecular', 'DNA Primers', 'Evolution, Molecular', 'Hordeum', 'Integrases', 'Molecular Sequence Data', 'Protein Structure, Secondary', 'Protein Structure, Tertiary', 'Retroelements', 'Sequence Homology, Amino Acid'] | 9,729,878 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.045.250', 'G16.075.250'], ['B01.650.940.800.575.912.250.822.481'], ['D08.811.739.500'], ['L01.453.245.667'], ['G02.111.570.820.709.60... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Ranitidine does not affect chlormethiazole or indocyanine green disposition. | Cimetidine has been shown to inhibit hepatic mixed-function oxidase activity and to lower hepatic blood flow. It is not known whether these effects are related to its H2-receptor antagonism or to its intrinsic structure. Ranitidine is a more potent H2-receptor antagonist and differs structurally from cimetidine. In our... | ['Adult', 'Chlormethiazole', 'Drug Interactions', 'Female', 'Furans', 'Humans', 'Indocyanine Green', 'Liver', 'Male', 'Ranitidine'] | 6,307,580 | [['M01.060.116'], ['D02.886.675.180', 'D03.383.129.708.180'], ['G07.690.773.968'], ['D03.383.312'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.400'], ['A03.620'], ['D03.383.312.750']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dynamic analysis of vascular morphogenesis using transgenic quail embryos. | BACKGROUND: One of the least understood and most central questions confronting biologists is how initially simple clusters or sheet-like cell collectives can assemble into highly complex three-dimensional functional tissues and organs. Due to the limits of oxygen diffusion, blood vessels are an essential and ubiquitous... | ['Animals', 'Animals, Genetically Modified', 'Blood Vessels', 'Cell Line', 'Cell Movement', 'Endothelial Cells', 'Humans', 'Mice', 'Models, Animal', 'Morphogenesis', 'Neovascularization, Physiologic', 'Quail'] | 20,856,866 | [['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['A07.015'], ['A11.251.210'], ['G04.198', 'G07.568.500.180'], ['A11.436.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.598'], ['G07.345.500'], ['G09.330.630'], ['B01.050.150.900.248.350.650']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treatment of porcine Pseudomonas ARDS with combination drug therapy. | A combination drug therapy (Poly-5: ibuprofen 12.5 mg/kg, methylprednisolone 30 mg/kg, cimetidine 150 mg, diphenhydramine 10 mg/kg, and ketanserin 0.2 mg/kg) given at 20 and 120 minutes after starting continuous intravenous Pseudomonas (Ps, 5 X 10(8) CFU/20 kg/min) was studied in three groups of swine: saline control (... | ['Animals', 'Blood Pressure', 'Capillary Permeability', 'Cardiac Output', 'Cimetidine', 'Diphenhydramine', 'Drug Combinations', 'Drug Therapy, Combination', 'Extracellular Space', 'Ibuprofen', 'Ketanserin', 'Lung', 'Methylprednisolone', 'Pseudomonas Infections', 'Respiratory Distress Syndrome', 'Serotonin', 'Swine'] | 3,694,722 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G03.143.330', 'G09.330.165'], ['E01.370.370.380.150', 'G09.330.380.124'], ['D02.078.370.200', 'D03.383.129.308.130'], ['D02.092.471.320', 'D02.455.426.559.389.115.250'], ['D26.310'], ['E02.319.310'], ['A10.082.500', 'A11.284.295'], ['D02.241.223.701.430'], ['D... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intracellular and extracellular acid-base status as a function of temperature in the freshwater channel catfish, Ictalurus punctatus. | The relationship between acid-base status and temperature was studied in the channel catfish, Ictalurus punctatus. The change in blood pH with temperature had a slope of -0.0132/degrees C and involved both a decrease in total CO2 at higher temperatures, and a significant rise in arterial PCO2. The acid-base changes in ... | ['Acclimatization', 'Acid-Base Equilibrium', 'Animals', 'Carbon Dioxide', 'Fishes', 'Gills', 'Hydrogen-Ion Concentration', 'Kidney', 'Temperature'] | 6,813,417 | [['G07.025.133', 'G16.012.500.133'], ['G02.111.007', 'G02.300.176', 'G03.030', 'G07.410.110', 'G09.188.050'], ['B01.050'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['B01.050.150.900.493'], ['A13.421'], ['G02.300'], ['A05.810.453'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Resonance based respiratory sound decomposition aiming at localization of crackles in noisy measurements. | In this work, resonance based decomposition of lung sounds that aims to separate wheeze, crackle and vesicular sounds into three individual channels while automatically localizing crackles for both synthetic and real data is presented. Previous works focus on stationary-non stationary discrimination to separate crackle... | ['Auditory Threshold', 'Auscultation', 'Humans', 'Respiratory Sounds', 'Signal Processing, Computer-Assisted', 'Signal-To-Noise Ratio', 'Sound'] | 28,269,094 | [['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['E01.370.600.060'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.779', 'E01.370.386.720', 'G09.772.775'], ['L01.224.800'], ['E05.318.370.800.875', 'E05.318.740.872.875', 'G17.800.500', 'N05.715.360.325.700.840', 'N05.715.360.750.725.... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
An easy method to demonstrate the cruciate ligaments by double contrast arthrography. | A reproducible technique which does not require special equipment for demonstrating the cruciate ligaments by double contrast arthrography is described. The positive contrast medium coats the synovial surfaces of the ligaments, i.e., the anterior aspect of the anterior cruciate ligament and the posterior aspect of the ... | ['Humans', 'Knee', 'Ligaments, Articular', 'Methods', 'Radiography'] | 628,763 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.450'], ['A02.513.514', 'A02.835.583.512', 'A10.165.669.514'], ['E05.581'], ['E01.370.350.700']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Freezing-assisted intracellular drug delivery to multidrug resistant cancer cells. | The efficacy of chemotherapy is significantly impaired by the multidrug resistance (MDR) of cancer cells. The mechanism of MDR is associated with the overexpression of certain adenosine triphosphate-binding cassette protein transporters in plasma membranes, which actively pump out cytotoxic drugs from the intracellular... | ['Antineoplastic Agents', 'Cell Line, Tumor', 'Cell Survival', 'Drug Delivery Systems', 'Drug Resistance, Multiple', 'Drug Resistance, Neoplasm', 'Freezing', 'Humans', 'Neoplasms'] | 19,640,149 | [['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['E02.319.300'], ['G07.690.773.984.300'], ['G07.690.773.984.395'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dental health knowledge in a group of Latin American refugees in Sweden. | Sixty-nine Latin American refugees with a mean age of 31 years participated in this study. The knowledge about dental health before and after reading a self-instructional manual in Spanish was tested by questionnaires. The test persons were also interviewed about their dietary habits. The results showed an improvement ... | ['Adult', 'Chile', 'Dietary Carbohydrates', 'Feeding Behavior', 'Female', 'Health Education, Dental', 'Humans', 'Latin America', 'Male', 'Manuals as Topic', 'Middle Aged', 'Programmed Instructions as Topic', 'Refugees', 'Sweden'] | 2,603,129 | [['M01.060.116'], ['Z01.107.757.235'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['I02.233.332.374', 'N02.421.726.407.457', 'N06.890.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.424'], ['L01.178.682.192.609', 'L01.178.820.500'], ['M01.060.... | ['Named Groups [M]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Neurocomputational mechanisms of adaptive learning in social exchanges. | Prior work on prosocial and self-serving behavior in human economic exchanges has shown that counterparts' high social reputations bias striatal reward signals and elicit cooperation, even when such cooperation is disadvantageous. This phenomenon suggests that the human striatum is modulated by the other's social value... | ['Adaptation, Psychological', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Altruism', 'Cooperative Behavior', 'Corpus Striatum', 'Feedback, Psychological', 'Female', 'Humans', 'Interpersonal Relations', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Reinforcement, Psychology', 'Young Adult'] | 30,756,349 | [['F01.058'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.145.813.090'], ['F01.145.813.115'], ['A08.186.211.200.885.287.249.487'], ['F01.058.288', 'F04.754.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['F... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Epithelial to mesenchymal transition in Cyclosporine A-induced rat gingival overgrowth. | BACKGROUND AND OBJECTIVE: Epithelial-mesenchymal transition (EMT) has been proved to occur in drug-induced gingival overgrowth. However, the specific pathogenic mechanism remains uncertain. The aim of this study is to examine the expression of EMT markers in cyclosporine A (CsA)-induced gingival overgrowth in rat model... | ['Animals', 'Biomarkers', 'Blotting, Western', 'Cyclosporine', 'Cytokines', 'Disease Models, Animal', 'Epithelial-Mesenchymal Transition', 'Gingival Overgrowth', 'Immunoenzyme Techniques', 'Male', 'Polymerase Chain Reaction', 'Rats', 'Rats, Sprague-Dawley'] | 28,472,720 | [['B01.050'], ['D23.101'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G04.356.500'], ['C07.465.714.258.428'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Universities in capacity building in sustainable development: focus on solid waste management and technology. | This paper analyses some of the higher education and research capacity building experiences gained from 1998-2006 by Danish and Malaysian universities. The focus is on waste management, directly relating to both the environmental and socio-economic dimensions of sustainable development. Primary benefits, available as a... | ['Conservation of Natural Resources', 'Denmark', 'Global Health', 'Health Services Research', 'Humans', 'Malaysia', 'Program Evaluation', 'Refuse Disposal', 'Time Factors', 'Universities', 'Waste Management'] | 17,612,324 | [['J01.256', 'N06.230.080'], ['Z01.542.816.124'], ['H02.403.371', 'N01.400.337'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.145.487'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['N06.850.780.200.800.800.700', 'N06.850.860.510.900.600'], ['G01.... | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
Square wave voltammetry based on determination of copper (II) ions by polyluteolin- and polykaempferol-modified electrodes. | Applicability of square wave voltammetry for the determination of Cu(II) ions by PolyLut/GC and PolyKae/GC electrodes was evaluated in this study. For this luteolin and kaempferol were electrochemically polymerized on glassy carbon (GC) electrode surface in order to get polyluteolin and polykaempferol-modified glassy c... | ['Carbon', 'Copper', 'Electrochemistry', 'Electrodes', 'Flavonoids', 'Glass', 'Kaempferols', 'Luteolin', 'Phenols', 'Polymers', 'Polyphenols', 'Surface Properties'] | 21,726,733 | [['D01.268.150'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['H01.181.529.307'], ['E07.305.250'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['J01.637.437'], ['D03.383.663.283.266.450.284.388', 'D03.633.100.150.266.450.284.388'], ['D03.383.663.283.266.450.260.555', 'D03.633.100.150.266.450... | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Use of a simple body-monitoring system in a pilot study on workers exposed to unsealed gamma-ray emitting material. | A portable body-monitoring system developed by the board uses two detectors, one for whole-body measurements and one for thyroid measurements. It can detect most commonly used gamma-ray emitting nuclides down to levels below those of interest for radiological protection purposes. The system has been used at 11 establis... | ['Gamma Rays', 'Humans', 'Pilot Projects', 'Radiation Monitoring', 'Thyroid Gland', 'Whole-Body Counting'] | 6,775,682 | [['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E05.799.638', 'N06.850.780.375.700', 'N06.850.810.370'], ['A06.300.900'], ['E05.799.950']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Localization of acetylated alpha-tubulin in Tritrichomonas foetus and Trichomonas vaginalis. | We used monoclonal antibodies specific for acetylated and nonacetylated alpha-tubulin to detect and to localize microtubules containing acetylated alpha-tubulin (stable microtubules) in the pathogenic protozoa Tritrichomonas foetus and Trichomonas vaginalis. SDS-PAGE analysis showed that tubulin is a major protein of b... | ['Acetylation', 'Animals', 'Antibodies, Monoclonal', 'Colchicine', 'Electrophoresis, Polyacrylamide Gel', 'Fluorescent Antibody Technique', 'Immunoblotting', 'Immunohistochemistry', 'Microscopy, Electron', 'Microtubules', 'Trichomonas vaginalis', 'Tritrichomonas', 'Tubulin', 'Vinblastine'] | 3,066,505 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D03.132.225'], ['E05.196.401.402', 'E05.301.300.319'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Biological indicators with a prognostic significance in neuroblastoma in children]. | Thanks to the recent progress made concerning the biology of neuroblastoma, we can now define with greater accuracy the progression and prognosis of these tumours. Several biologic profiles distinguish the neuroblastoma at stage IV-S, the prognosis of which is usually good, thus providing it with a true biological iden... | ['Catecholamines', 'Child', 'Child, Preschool', 'DNA, Neoplasm', 'Ferritins', 'Gangliosides', 'Humans', 'Infant', 'Neoplasm Staging', 'Neuroblastoma', 'Phosphopyruvate Hydratase', 'Prognosis'] | 3,359,058 | [['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['M01.060.406'], ['M01.060.406.448'], ['D13.444.308.425'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['D09.400.410.420.025.475', 'D10.390.470.025.475', 'D10.570.877.360.025.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E01.789.625']... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Apoptotic response of spermatogenic cells to the germ cell mutagens etoposide, adriamycin, and diepoxybutane. | In testis, apoptosis is a way to eliminate damaged germ cells during their development. In this study, we evaluated the ability of three germ cell mutagens to induce apoptosis (or programmed cell death) at specific stages of rat seminiferous epithelial cycle. These chemicals include the cancer chemotherapy drugs etopos... | ['Animals', 'Antibiotics, Antineoplastic', 'Antineoplastic Agents, Phytogenic', 'Apoptosis', 'Cyclin-Dependent Kinase Inhibitor p21', 'Cyclins', 'Doxorubicin', 'Epoxy Compounds', 'Etoposide', 'Gene Expression', 'Male', 'Mutagens', 'Nuclear Proteins', 'Paraffin Embedding', 'Proto-Oncogene Proteins', 'Proto-Oncogene Prot... | 9,544,191 | [['B01.050'], ['D27.505.954.248.106'], ['D27.505.954.248.179'], ['G04.146.954.035'], ['D12.644.360.225.500', 'D12.776.157.687.250', 'D12.776.167.187.500', 'D12.776.476.225.500', 'D12.776.624.776.355.500', 'D12.776.660.720.250'], ['D12.644.360.262', 'D12.776.167.218', 'D12.776.476.262'], ['D02.455.426.559.847.562.050.20... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prognosticators in recurrent breast cancer. A 15-year experience with irradiation. | After initial surgery, 133 breast cancer patients, who did not receive postoperative radiation or chemotherapy, were subsequently irradiated for recurrences in the Department of Radiation Oncology, University of Maryland Hospital. All patients have been followed for a minimum of 5 years after the treatment of recurrenc... | ['Adult', 'Aged', 'Breast Neoplasms', 'Carcinoma, Intraductal, Noninfiltrating', 'Combined Modality Therapy', 'Female', 'Humans', 'Lymphatic Metastasis', 'Mastectomy', 'Menopause', 'Middle Aged', 'Neoplasm Metastasis', 'Neoplasm Recurrence, Local', 'Prognosis', 'Radiotherapy Dosage', 'Retrospective Studies', 'Time Fact... | 6,327,002 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.275', 'C04.557.470.200.240.187.250', 'C04.557.470.615.275'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['E04.466'], ['G08.686.157.500', 'G08.686.841.249.500'],... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An evidence-based guideline for the management of heavy menstrual bleeding. Working Party for Guidelines for the Management of Heavy Menstrual Bleeding. | AIMS: The objective of this guideline is to provide evidence-based recommendations for the management of regular heavy menstrual bleeding in women with no detectable pathology.METHODS: A multidisciplinary working party was formed which met on four occasions over a 12 month period. The evidence from randomised controlle... | ['Adult', 'Algorithms', 'Anti-Inflammatory Agents, Non-Steroidal', 'Contraceptives, Oral', 'Evidence-Based Medicine', 'Female', 'Humans', 'Menorrhagia', 'Middle Aged', 'Progesterone'] | 10,391,640 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D27.505.696.875.360.276.210', 'D27.505.954.705.360.276.210'], ['H02.249.750', 'H02.403.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.852.691.449', 'C23.550.414.9... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 |
[Treatment of 63 advanced ovarian carcinomas]. | 62 patients with advanced epithelial ovarian adenocarcinoma (37 stage III, 4 stage IV and 22 recurrent lesions) were treated in our hospital from 1977 to 1981, 38 patients underwent surgery. 25 with inoperable tumor initially received preoperative chemotherapy (VCF protocol: vincristine + cyclophosphamide + fluorouraci... | ['Adenocarcinoma', 'Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Combined Modality Therapy', 'Cyclophosphamide', 'Female', 'Fluorouracil', 'Humans', 'Middle Aged', 'Ovarian Neoplasms', 'Vincristine'] | 3,452,529 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.186'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.322.455', 'C13.351.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Two ears and two (or more?) devices: a pediatric case study of bilateral profound hearing loss. | Advances in technology and expanding candidacy guidelines have motivated many clinics to consider children with precipitously sloping high-frequency hearing loss as candidates for cochlear implants (CIs). A case study is presented of a pediatric CI patient whose hearing thresholds were preserved within 10 dB of preimpl... | ['Audiometry', 'Auditory Pathways', 'Auditory Threshold', 'Child', 'Child, Preschool', 'Cochlear Implantation', 'Cochlear Implants', 'Combined Modality Therapy', 'Correction of Hearing Impairment', 'Emotions', 'Female', 'Hearing Aids', 'Hearing Loss, High-Frequency', 'Humans', 'Perceptual Masking', 'Persons With Hearin... | 19,447,765 | [['E01.370.382.375.060'], ['A08.612.220.110'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['M01.060.406'], ['M01.060.406.448'], ['E04.580.450.220', 'E04.650.220'], ['E07.305.250.319.381.500.500', 'E07.695.150', 'E07.695.202.381.500.500', 'E07.814.458.150'], ['E02.186'], ['E02.760.169.063.500.200... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Four-year follow-up of women who were diagnosed to have postpartum urinary retention. | OBJECTIVE: The purpose of this study was to evaluate the long-term prevalence of urinary incontinence in women with postpartum urinary retention.STUDY DESIGN: A telephone interview was conducted by contacting a cohort of 691 women who delivered vaginally 4 years ago, of which 101 women had been diagnosed as having post... | ['Female', 'Follow-Up Studies', 'Humans', 'Logistic Models', 'Prevalence', 'Puerperal Disorders', 'Time Factors', 'Urinary Incontinence, Stress', 'Urinary Retention'] | 12,237,642 | [['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450', 'N05.715.360.750.695.470', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Intraventricular pressure gradients in heart failure. | The aim of the present study was to characterize intraventricular pressure gradients (IVPGs) in an animal model of chronic heart failure. New Zealand rabbits were treated with doxorubicin (heart failure group, n=5) or saline (control group, n=5) and instrumented with pressure catheters placed in the apex and outflow-tr... | ['Animals', 'Chronic Disease', 'Diastole', 'Disease Models, Animal', 'Doxorubicin', 'Heart Failure', 'Rabbits', 'Systole', 'Time Factors', 'Ultrasonography', 'Ventricular Dysfunction, Left', 'Ventricular Function, Left', 'Ventricular Pressure'] | 24,020,813 | [['B01.050'], ['C23.550.291.500'], ['G09.330.580.295', 'G11.427.494.554.250', 'G11.427.494.570.295'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['C14.280.434'], ['B01.050.150.900.649.313.968.700'], ['G09.330.580.880', 'G... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Being victims or beneficiaries? Perspectives on female genital cutting and reinfibulation in Sudan. | Female Genital Mutilation (FGM) or the more value neutral term, Female Genital Cutting (FGC) is widely practised in northern Sudan, where around 90% of women undergo the most extensive form of FGC, infibulation. One new approach to combating FGC in Sudan is to acknowledge the previously hidden form of FGC, reinfibulati... | ['Circumcision, Female', 'Culture', 'Female', 'Humans', 'Male', 'Perception', 'Sex Factors', 'Sexual Behavior', 'Sudan', "Women's Health"] | 17,217,115 | [['E02.218.085.165', 'E04.085.165', 'E04.950.300.200', 'I01.076.201.450.199'], ['I01.076.201.450', 'I01.880.853.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593'], ['N05.715.350.675', 'N06.850.490.875'], ['F01.145.802'], ['Z01.058.290.120.760'], ['N01.400.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Contortrostatin, a homodimeric disintegrin, binds to integrin alphavbeta5. | Contortrostatin is a homodimeric disintegrin from snake venom. We have shown that contortrostatin binds to integrins alphaIIbbeta3, alpha5beta1, and alphavbeta3. We now use several criteria to demonstrate the binding of contortrostatin to alphavbeta5. First, incubation of T24 cells, which express alphavbeta3 and alphav... | ['Agkistrodon', 'Animals', 'Binding Sites', 'Cell Adhesion', 'Dimerization', 'Disintegrins', 'Humans', 'Integrins', 'Kinetics', 'Neoplasm Invasiveness', 'Radioligand Assay', 'Receptors, Vitronectin', 'Tumor Cells, Cultured', 'Urinary Bladder Neoplasms', 'Viper Venoms'] | 10,623,623 | [['B01.050.150.900.833.672.125.937.240.250'], ['B01.050'], ['G02.111.570.120'], ['G04.022'], ['G02.206', 'G03.230'], ['D12.644.138'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543.750.705.408'], ['G01.374.661', 'G02.111.490'], ['C04.697.645', 'C23.550.727.645'], ['E01.370.225.985', 'E01.370.374.650', '... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adverse obstetric outcomes at term after hysteroscopic metroplasty. | STUDY OBJECTIVE: To estimate obstetrical complications at term after hysteroscopic metroplasty for septate uterus.DESIGN: A retrospective comparative study (Canadian Task Force classification II-2).SETTING: La Conception Hospital, Department of Obstetrics and Gynecology, Marseille, France.PATIENTS AND INTERVENTIONS: Th... | ['Adult', 'Breech Presentation', 'Case-Control Studies', 'Cesarean Section', 'Female', 'Gynecologic Surgical Procedures', 'Humans', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Pregnancy', 'Retrospective Studies', 'Risk', 'Uterus', 'Young Adult'] | 19,573,822 | [['M01.060.116'], ['C13.703.420.183', 'G08.686.520.150', 'G08.686.784.769.326.520.150'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E04.520.252.500'], ['E04.950.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520.460'], ['M01.060.703.520'], ['G08.686.784.769']... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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