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A pilot study of patient-specific cardiovascular MDCT dose maps and their utility in estimating patient-specific organ and effective doses in obese patients. | BACKGROUND: Estimates of effective dose (E) for cardiovascular CT are obtained from a scanner-provided dose metric, the dose-length product (DLP), and a conversion factor. These estimates may not adequately represent the risk of a specific scan to obese adults.OBJECTIVE: Our objective was to create dose maps sensitive ... | ['Aorta, Thoracic', 'Aortography', 'Body Mass Index', 'Cardiovascular Diseases', 'Computed Tomography Angiography', 'Coronary Angiography', 'Coronary Vessels', 'Humans', 'Monte Carlo Method', 'Multidetector Computed Tomography', 'Obesity', 'Patient-Specific Modeling', 'Phantoms, Imaging', 'Phlebography', 'Pilot Project... | 26,853,972 | [['A07.015.114.056.372'], ['E01.370.350.700.060.070', 'E01.370.370.050.070'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C14'], ['E01.370.350.350.810.335', 'E01.370.350.567.250', 'E01.370.350.600.350.700.810.335', 'E01.370.350.700.700.810.335', 'E01.370.350.700.810.8... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
How singleton breech babies at term are born in France: a survey of data from the AUDIPOG network. | Based on data from the AUDIPOG sentinel network between 1994 and 2010, we can say that the rate of singleton breech presentation at term is 3% and remains unchanged despite an external cephalic version rate of 35%. The total cesarean section rate is currently 75%. This rate increased by nearly 20% after the Hannah publ... | ['Adult', 'Birth Weight', 'Breech Presentation', 'Cesarean Section', 'Delivery Rooms', 'Episiotomy', 'Female', 'France', 'Humans', 'Infant, Newborn', 'Intensive Care, Neonatal', 'Pregnancy', 'Term Birth', 'Version, Fetal', 'Young Adult'] | 25,801,722 | [['M01.060.116'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['C13.703.420.183', 'G08.686.520.150', 'G08.686.784.769.326.520.150'], ['E04.520.252.500'], ['N02.278.388.150'], ['E04.520.252.750'], ['Z01.542.286'], ['B01.050.150.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Detection of antibodies against Trypanosoma cruzi in Somoto, Nicaragua, using indirect ELISA and IFI on blood samples on filter paper]. | We standardized a solid-phase enzyme-linked immunosorbent assay (ELISA) in order to study the presence of Trypanosoma cruzi antibodies in asymptomatic persons who live in an area of Nicaragua endemic for Chagas' disease. The test was standardized to analyze filter-paper blood samples, which are easy to transport. In th... | ['Adolescent', 'Adult', 'Age Distribution', 'Animals', 'Antibodies, Protozoan', 'Chagas Disease', 'Child', 'Child, Preschool', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Filtration', 'Fluorescent Antibody Technique, Indirect', 'Humans', 'Infant', 'Infant, Newborn', 'Leishmaniasis, Cutaneous', 'Leishmaniasis, Visce... | 11,209,254 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['B01.050'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['C01.610.752.300.900.200', 'C01.920.625'], ['M01.060.406'], ['M01.060.406.448'], ['E05.478.566.350.170', 'E05.478.566.380... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Electron microscopy procedure influences detection of rotaviruses. | Technical parameters of electron microscope staining procedures (type of stain, pH of stain, and time of staining) influence particle integrity for three groups of rotaviruses. Simian rotavirus SA11 (group A), Chinese adult diarrhea rotavirus and porcine rotavirus-like agent (group B), and porcine pararotavirus (group ... | ['Animals', 'Gastroenteritis', 'Humans', 'Hydrogen-Ion Concentration', 'Microscopy, Electron', 'Molybdenum', 'Organometallic Compounds', 'Phosphotungstic Acid', 'Rotavirus', 'Rotavirus Infections', 'Staining and Labeling'] | 2,444,622 | [['B01.050'], ['C06.405.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E01.370.350.515.402', 'E05.595.402'], ['D01.268.556.555', 'D01.268.956.500', 'D01.552.544.555'], ['D02.691'], ['D01.029.260.700.675.750', 'D01.695.625.675.750', 'D01.940.700'], ['B04.820.223.719.790'], ['C01.925.782.791.814']... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Spanish health care system: lessons for newly industrialized countries. | This article summarizes the organization, financing, and delivery of health care services in Spain, and discusses the elements that made it possible to maintain high levels of health among the population, while spending comparatively fewer resources on the health care system than most industrialized countries. The case... | ['Delivery of Health Care', 'Developed Countries', 'Efficiency, Organizational', 'Financing, Government', 'Global Health', 'Health Care Rationing', 'Health Expenditures', 'Health Status Indicators', 'Health Workforce', 'Hospitals, Public', 'National Health Programs', 'Primary Health Care', 'Public Health Administration... | 10,538,719 | [['N04.590.374', 'N05.300'], ['I01.615.500.250'], ['N04.452.209.500'], ['N03.219.521.346'], ['H02.403.371', 'N01.400.337'], ['I01.261.750.500', 'N03.349.270', 'N05.300.430.375'], ['N03.219.151.450', 'N05.300.385'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['N02.350', 'N... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
The FGF2 gene in a myopia animal model and human subjects. | PURPOSE: Fibroblast growth factor-2 (FGF2) has been implied in the development of myopia according to previous studies investigating FGF2 in the sclera and retinal pigment epithelium. This study measured retinal FGF2 gene expression in an animal model and also tested for the association between single nucleotide polymo... | ['Adolescent', 'Adult', 'Animals', 'Axial Length, Eye', 'Biometry', 'Case-Control Studies', 'Disease Models, Animal', 'Female', 'Fibroblast Growth Factor 2', 'Gene Expression', 'Genotype', 'Guinea Pigs', 'Humans', 'Male', 'Middle Aged', 'Myopia', 'Polymorphism, Single Nucleotide', 'RNA, Messenger', 'Refraction, Ocular'... | 22,393,273 | [['M01.060.057'], ['M01.060.116'], ['B01.050'], ['A09.371.199', 'E01.370.600.115.100.660.500'], ['E05.318.740.225', 'N06.850.505.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.62... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
High-yield isolation of protoplasts from microgram amounts of shoot meristematic tissues and rapid DNA content determination by flow cytometry. | This paper describes a novel approach to rapid cell-cycle analysis of shoot meristematic cells. The method involves fixation and disaggregation of meristems into protoplast suspension and flow-cytometric analysis of these protoplasts stained with fluorescent dyes. We have developed a procedure for a high-yield isolatio... | ['Cell Cycle', 'Cell Fractionation', 'Cell Nucleus', 'DNA', 'Flow Cytometry', 'Plant Cells', 'Plants', 'Protoplasts', 'Species Specificity'] | 1,959,553 | [['G04.144'], ['E05.242.251'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D13.444.308'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['A11.750'], ['B01.650'], ['A11.789'], ['G16.824'... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Volume electron microscopy of the distribution of synapses in the neuropil of the juvenile rat somatosensory cortex. | Knowing the proportions of asymmetric (excitatory) and symmetric (inhibitory) synapses in the neuropil is critical for understanding the design of cortical circuits. We used focused ion beam milling and scanning electron microscopy (FIB/SEM) to obtain stacks of serial sections from the six layers of the juvenile rat (p... | ['Animals', 'Animals, Newborn', 'Dendrites', 'Dendritic Spines', 'Male', 'Microscopy, Electron', 'Neuropil', 'Rats', 'Somatosensory Cortex', 'Statistics, Nonparametric', 'Synapses'] | 28,721,455 | [['B01.050'], ['B01.050.050.282'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['A08.675.256.200', 'A11.284.180.225.169', 'A11.671.240.169'], ['E01.370.350.515.402', 'E05.595.402'], ['A08.637.500', 'A08.675.703', 'A11.650.500', 'A11.671.685'], ['B01.050.150.900.649.313.992.635.505.700'], ['A08.186.211.200.885.28... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pancreatic juice cytology for monitoring pancreatic grafts in the early postoperative period. | Thirty-one pancreas transplant recipients were monitored by pancreatic juice cytology in the early postoperative period. An increase in the total amount of cells and, in particular, signs of immunoactivation with the appearance of two or more blast-transformed cells per specimen were taken as evidence of acute rejectio... | ['Adolescent', 'Adult', 'Amylases', 'Antigens, Differentiation, T-Lymphocyte', 'Bacteria', 'CD3 Complex', 'Female', 'Fungi', 'Graft Rejection', 'Humans', 'Lymphocytes', 'Male', 'Middle Aged', 'Pancreas Transplantation', 'Pancreatic Juice', 'Receptors, Antigen, T-Cell'] | 1,381,177 | [['M01.060.057'], ['M01.060.116'], ['D08.811.277.450.066'], ['D23.050.301.264.894', 'D23.101.100.894'], ['B03'], ['D23.050.301.264.894.095', 'D23.101.100.894.095'], ['B01.300'], ['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Predicting breast cancer risk using personal health data and machine learning models. | Among women, breast cancer is a leading cause of death. Breast cancer risk predictions can inform screening and preventative actions. Previous works found that adding inputs to the widely-used Gail model improved its ability to predict breast cancer risk. However, these models used simple statistical architectures and ... | ['Aged', 'Breast Neoplasms', 'Female', 'Health Records, Personal', 'Humans', 'Machine Learning', 'Middle Aged', 'ROC Curve', 'Risk Assessment'] | 31,881,042 | [['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.308.940.968.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G17.035.250.500', 'L01.224.050.375.530'], ['M01.060.116.630'], ['E05.318.370.800.750', 'E05.318.740.872.750', 'N05.715.360.325.700.680', 'N06.850.520.445.800.750'], ['E05.318.740.600... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Reliability of laser Doppler, near-infrared spectroscopy and Doppler ultrasound for peripheral blood flow measurements during and after exercise in the heat. | This study examined the test-retest reliability of near-infrared spectroscopy (NIRS), laser Doppler flowmetry (LDF) and Doppler ultrasound to assess exercise-induced haemodynamics. Nine men completed two identical trials consisting of 25-min submaximal cycling at first ventilatory threshold followed by repeated 30-s bo... | ['Adult', 'Exercise', 'Exercise Test', 'Hemodynamics', 'Hemoglobinometry', 'Hot Temperature', 'Humans', 'Laser-Doppler Flowmetry', 'Leg', 'Male', 'Muscle, Skeletal', 'Oxygen Consumption', 'Regional Blood Flow', 'Reproducibility of Results', 'Skin', 'Spectroscopy, Near-Infrared', 'Ultrasonography, Doppler'] | 27,649,579 | [['M01.060.116'], ['G11.427.410.698.277', 'I03.350'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['G09.330.380'], ['E01.370.225.625.410', 'E05.200.625.410'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Affective experience and motivated behavior in schizophrenia spectrum disorders: Evidence from clinical and nonclinical samples. | OBJECTIVE: Individuals with schizophrenia have been found to exhibit emotion-behavior decoupling, particularly with respect to anticipated, rather than experienced events. However, previous research has focused on how emotion valence translates into motivated behavior, ignoring the fact that emotion arousal should also... | ['Adult', 'Anhedonia', 'Anticipation, Psychological', 'Emotions', 'Female', 'Humans', 'Male', 'Middle Aged', 'Motivation', 'Pleasure', 'Schizophrenia', 'Schizotypal Personality Disorder'] | 26,986,747 | [['M01.060.116'], ['C10.597.606.057', 'C23.888.592.604.039', 'F01.700.039'], ['F02.463.093'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.658', 'F01.752.543.500.750'], ['F01.470.867', 'F02.830.816.492'], ['F03.700.750'], ['F03.675.725']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evaluation of interferences between dengue vaccine serotypes in a monkey model. | Interferences between different antigens in the same vaccine formulation have been reported for some vaccines (e.g., polio vaccines, live attenuated dengue vaccine candidates). We examined interferences between the four serotypes of ChimeriVax dengue vaccines (CYDs) in a monkey model when present within a tetravalent f... | ['Animals', 'Antibodies, Viral', 'Cell Line', 'Chlorocebus aethiops', 'Dengue', 'Dengue Vaccines', 'Dengue Virus', 'Disease Models, Animal', 'Humans', 'Immunization Schedule', 'Immunization, Secondary', 'Macaca fascicularis', 'Male', 'Neutralization Tests', 'Serotyping', 'Vaccination', 'Vero Cells', 'Viral Interference... | 19,190,230 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['C01.920.500.270', 'C01.925.081.270', 'C01.925.782.350.250.214', 'C01.925.782.417.214'], ['D20.215.894.899.162'], ['B04.820.578.344.350.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Differential expression of the angiogenic Tie receptor family in arthritic and normal synovial tissue. | Angiopoietins (Ang) are vascular endothelial cell-specific growth factors that play important roles principally during the later stages of angiogenesis. We have compared the distribution of the receptor tyrosine kinase (Tie) and the Ang ligands in synovial tissues from normal subjects and those with rheumatoid arthriti... | ['Angiopoietin-1', 'Angiopoietin-2', 'Arthritis, Rheumatoid', 'Cells, Cultured', 'Endothelium', 'Fibroblasts', 'Humans', 'Immunoenzyme Techniques', 'Macrophages', 'Membrane Glycoproteins', 'Osteoarthritis', 'Proteins', 'RNA, Messenger', 'Receptor Protein-Tyrosine Kinases', 'Receptor, TIE-1', 'Receptor, TIE-2', 'Recepto... | 12,010,571 | [['D12.644.276.100.100.100', 'D12.776.467.100.100.100', 'D23.529.100.100.100'], ['D12.644.276.100.100.200', 'D12.776.467.100.100.200', 'D23.529.100.100.200'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['A11.251'], ['A10.272.491'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The score for allergic rhinitis (SFAR): a simple and valid assessment method in population studies. | BACKGROUND: No validated assessment of allergic rhinitis (AR) is presently available that can be used in population studies in the absence of medical diagnosis and of objective measurements of allergy. To compensate for this lack, a quantitative Score For Allergic Rhinitis (SFAR) ranging between 0 and 16 has been devel... | ['Adolescent', 'Adult', 'Age Factors', 'False Positive Reactions', 'Female', 'France', 'Humans', 'Male', 'Predictive Value of Tests', 'ROC Curve', 'Random Allocation', 'Rhinitis, Allergic, Perennial', 'Rhinitis, Allergic, Seasonal', 'Sensitivity and Specificity', 'Skin Tests'] | 11,929,412 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.354.506'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E05.318.370.800.750', 'E05.318.740.872.750', 'N05.715.360.325.700.680', 'N06.850.... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cadmium transport in isolated perfused rat liver: zinc-cadmium competition. | The hypothesis that one component of cadmium uptake by rat hepatocytes involves a mediated transport pathway normally operative for zinc transport was tested in the isolated perfused rat liver preparation. Excess zinc in the perfusion medium suppressed cadmium uptake as indicated by the decrease in the normalized clear... | ['Animals', 'Biological Transport, Active', 'Cadmium', 'In Vitro Techniques', 'Kinetics', 'Liver', 'Male', 'Perfusion', 'Rats', 'Zinc'] | 426,045 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of quercetin as a potential drug in osteosarcoma treatment. | BACKGROUND: Osteosarcoma is the most common malignant bone tumor in children and young adults. Since the introduction of chemotherapy, the 5-year survival rate of patients with non-metastatic osteosarcoma is ~70%. The main problems in osteosarcoma therapy are the occurrence of metastases, severe side-effects and chemor... | ['Antioxidants', 'Apoptosis', 'Blotting, Western', 'Bone Neoplasms', 'Cell Adhesion', 'Cell Cycle', 'Cell Movement', 'Cell Proliferation', 'Flow Cytometry', 'Humans', 'Osteosarcoma', 'Quercetin', 'Tumor Cells, Cultured', 'Wound Healing'] | 23,564,766 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C04.588.149', 'C05.116.231'], ['G04.022'], ['G04.144'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['E0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Liver cirrhosis caused by alpha-1-antitrypsin deficiency]. | The authors present 2 patients with cirrhosis of the liver associated with alpha-1-antitrypsin deficiency. The patients are two children (brother and sister aged 4 and 13). The manifestation of the disease in these two children was a prolonged neonatal icterus. The symptoms of a decompensated cirrhosis of the liver app... | ['Child', 'Child, Preschool', 'Female', 'Humans', 'Liver Cirrhosis', 'Male', 'Phenotype', 'alpha 1-Antitrypsin', 'alpha 1-Antitrypsin Deficiency'] | 2,787,094 | [['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.355.412'], ['G05.695'], ['D12.644.861.035', 'D12.776.124.050.070', 'D12.776.124.790.106.085', 'D12.776.377.715.085.085', 'D12.776.395.068', 'D12.776.872.035'], ['C06.552.074', 'C08.381.112', 'C16.320.060', '... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Long-Term Follow-Up after Surgery for Congenital and Developmental Cataracts. | PURPOSE: To evaluate long-term functional outcomes after surgery for congenital and developmental cataracts.METHODS: In this retrospective interventional study, patients with congenital and developmental cataracts observed from 1996 to 2013 were included. Traumatic cataracts and cataracts secondary to other pathologies... | ['Aphakia, Postcataract', 'Cataract', 'Cataract Extraction', 'Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Lens Implantation, Intraocular', 'Male', 'Myopia', 'Pseudophakia', 'Retrospective Studies', 'Strabismus', 'Vision, Binocular', 'Visual Acuity'] | 25,323,995 | [['C11.510.103.110'], ['C11.510.245'], ['E04.540.825.249'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E04.540.825.600'], ['C11.744.636'], ['C23.888.681'], ['E05.318.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prognostic significance of peanut agglutinin binding in childhood acute lymphoblastic leukemia. | We previously reported the favorable prognosis associated with positive peanut agglutinin (PNA) binding in childhood T cell acute lymphoblastic leukemia (ALL), and hypothesized that this may be related to glucocorticoid sensitivity (Veerman et al. Cancer Res 1985, 45: 1890). The purposes of this prospective study invol... | ['Adolescent', 'Antineoplastic Agents, Hormonal', 'Antineoplastic Combined Chemotherapy Protocols', 'Arachis', 'Bone Marrow', 'Child', 'Child, Preschool', 'Dexamethasone', 'Drug Resistance, Neoplasm', 'Female', 'Humans', 'Immunophenotyping', 'Infant', 'Injections, Spinal', 'Lectins', 'Leukemia-Lymphoma, Adult T-Cell', ... | 8,618,446 | [['M01.060.057'], ['D27.505.954.248.169'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['B01.650.940.800.575.912.250.401.077'], ['A15.382.216'], ['M01.060.406'], ['M01.060.406.448'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['G07.690.773.984.395'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Combining DC algorithms (DCAs) and decomposition techniques for the training of nonpositive-semidefinite kernels. | Today, decomposition methods are one of the most popular methods for training support vector machines (SVMs). With the use of kernels that do not satisfy Mercer's condition, new techniques must be designed to handle nonpositive-semidefinite kernels resulting to this choice. In this work we incorporate difference of con... | ['Algorithms', 'Artificial Intelligence', 'Computer Simulation', 'Models, Theoretical', 'Pattern Recognition, Automated'] | 18,990,641 | [['G17.035', 'L01.224.050'], ['G17.035.250', 'L01.224.050.375'], ['L01.224.160'], ['E05.599'], ['L01.399.750']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Regional left atrial function differentiation in patients with constrictive pericarditis and restrictive cardiomyopathy: a study using speckle tracking echocardiography. | Left atrial (LA) function plays an important role in the maintenance of cardiac output. However, whether assessment of regional LA myocardial dysfunction is useful for differentiating between CP and restrictive cardiomyopathy (RCM) remains unclear. Thirty-five patients with CP, 30 patients with RCM, and 30 healthy volu... | ['Adult', 'Atrial Function, Left', 'Biomechanical Phenomena', 'Cardiomyopathy, Restrictive', 'Case-Control Studies', 'Diagnosis, Differential', 'Echocardiography', 'Female', 'Heart Atria', 'Humans', 'Male', 'Middle Aged', 'Myocardial Contraction', 'Pericarditis, Constrictive', 'Predictive Value of Tests', 'Prospective ... | 26,245,471 | [['M01.060.116'], ['G09.330.040.100'], ['G01.154.090', 'G01.374.089'], ['C14.280.238.160'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.171'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['A07.541.358'], ['B01.050.150.900.649.313.988.400.112.400.400'],... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
IL-6 increases muscle insulin sensitivity only at superphysiological levels. | Exercise induces an increase in glucose transport in muscle. As the acute increase in glucose transport reverses, it is replaced by an increase in insulin sensitivity. Interleukin-6 (IL-6) increases with exercise and has been reported to activate AMP-activated protein kinase (AMPK). Based on this information, we hypoth... | ['AMP-Activated Protein Kinases', 'Animals', 'Biological Transport', 'Dose-Response Relationship, Drug', 'Enzyme Activation', 'Forelimb', 'Glucose', 'Hindlimb', 'Insulin', 'Interleukin-6', 'Male', 'Multienzyme Complexes', 'Muscle, Skeletal', 'Protein-Serine-Threonine Kinases', 'Rats', 'Rats, Wistar', 'Time Factors'] | 17,327,367 | [['D08.811.913.696.620.682.700.085', 'D12.644.360.062', 'D12.776.476.062'], ['B01.050'], ['G03.143'], ['G07.690.773.875', 'G07.690.936.500'], ['G02.111.263', 'G03.328'], ['A13.395'], ['D09.947.875.359.448'], ['A13.473'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D12.644.276.374.465.224', 'D12.77... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genetic Diversity and Population Structure in South African, French and Argentinian Angora Goats from Genome-Wide SNP Data. | The Angora goat populations in Argentina (AR), France (FR) and South Africa (SA) have been kept geographically and genetically distinct. Due to country-specific selection and breeding strategies, there is a need to characterize the populations on a genetic level. In this study we analysed genetic variability of Angora ... | ['Animals', 'Argentina', 'Chromosomes, Mammalian', 'France', 'Genetic Markers', 'Genetic Variation', 'Genetics, Population', 'Genome', 'Goats', 'Linkage Disequilibrium', 'Polymorphism, Single Nucleotide', 'Population Density', 'Principal Component Analysis', 'Reproducibility of Results', 'South Africa', 'Statistics as ... | 27,171,175 | [['B01.050'], ['Z01.107.757.077'], ['A11.284.187.520', 'G05.360.162.520'], ['Z01.542.286'], ['D23.101.387', 'G05.695.450'], ['G05.365'], ['H01.158.273.343.335'], ['G05.360.340'], ['B01.050.150.900.649.313.500.380.513'], ['G05.348.500'], ['G05.365.795.598'], ['N01.224.600', 'N06.850.505.400.600'], ['E05.318.740.562'], [... | ['Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Comparative genomic analysis of two-component regulatory proteins in Pseudomonas syringae. | BACKGROUND: Pseudomonas syringae is a widespread bacterial plant pathogen, and strains of P. syringae may be assigned to different pathovars based on host specificity among different plant species. The genomes of P. syringae pv. syringae (Psy) B728a, pv. tomato (Pto) DC3000 and pv. phaseolicola (Pph) 1448A have been re... | ['Bacterial Proteins', 'Chemotactic Factors', 'Chromosome Mapping', 'Gene Expression Regulation, Bacterial', 'Genome, Bacterial', 'Histidine Kinase', 'Host-Parasite Interactions', 'Models, Biological', 'Multigene Family', 'Protein Kinases', 'Pseudomonas syringae', 'Transcription Factors'] | 17,971,244 | [['D12.776.097'], ['D23.125'], ['E05.393.183'], ['G05.308.300'], ['G05.360.340.358.207'], ['D08.811.913.696.620.682.424'], ['G16.527.200.400'], ['E05.599.395'], ['G05.360.340.024.340.645'], ['D08.811.913.696.620.682'], ['B03.440.400.425.625.625.770', 'B03.660.250.580.590.770'], ['D12.776.930']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Age-related changes in the antioxidative potential of cerebral microvessels. | To determine if aging in rats is associated with increased susceptibility of cerebral microvessels to oxidative damage microvessels from the cerebrum of 4-, 12-, 18- and 26-month-old male Fischer 344 rats were studied. The malondialdehyde (MDA) (micrograms/mg protein) content of cerebral microvessels from 12-month-old ... | ['Aging', 'Amidines', 'Animals', 'Antioxidants', 'Free Radicals', 'Lipid Peroxidation', 'Male', 'Malondialdehyde', 'Microcirculation', 'Phycoerythrin', 'Prosencephalon', 'Rats', 'Rats, Inbred F344'] | 7,728,528 | [['G07.345.124'], ['D02.078'], ['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D01.339', 'D02.389'], ['G02.111.515', 'G03.295.531.587'], ['D02.047.700'], ['G09.330.100.645'], ['D05.500.562.488.490.500.500.777', 'D08.811.600.710.490.500.500.777', 'D12.776.765.665', 'D23.767.705'], ['A08.186... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association between EPCs count and rate of coronary revascularization in asymptomatic type 2 diabetic patients. | Coronary arterial disease (CAD) is common in diabetic patients, and endothelial progenitor cells (EPCs) are considered a surrogate marker for CAD, but controversies regarding this issue still remain. We investigated the potential clinical role of EPCs during coronary screening in asymptomatic type 2 diabetic patients s... | ['Adult', 'Aged', 'Asymptomatic Diseases', 'Case-Control Studies', 'Cell Count', 'Coronary Angiography', 'Coronary Artery Disease', 'Diabetes Mellitus, Type 2', 'Diabetic Angiopathies', 'Endothelial Cells', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myocardial Revascularization', 'Stem Cells'] | 22,160,247 | [['M01.060.116'], ['M01.060.116.100'], ['C23.550.291.187'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of unesterified cholesterol on the compartmentation of a fluorescent cholesteryl ester in a lipoprotein-like lipid microemulsion. | The access of enzymes and lipid transfer proteins to neutral lipids located predominantly in the core compartment of lipoproteins may be determined to some degree by the solubility of the neutral lipids in the surface monolayer of phospholipid. This report concerns the hypothesis that unesterfied cholesterol can affect... | ['Cholesterol', 'Cholesterol Esters', 'Dimyristoylphosphatidylcholine', 'Emulsions', 'Esterification', 'Lipid Metabolism', 'Lipoproteins', 'Membranes', 'Microscopy, Electron', 'Particle Size', 'Solubility', 'Spectrometry, Fluorescence'] | 1,527,474 | [['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.222.284.200', 'D04.210.500.247.808.197.200', 'D10.570.938.208.250'], ['D10.570.755.375.760.400.800.200'], ['D20.280.260', 'D26.255.165.260'], ['G02.111.270', 'G02.607.250', 'G03.344'], ['G03.458'], ['D10.532', 'D12.776.521'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Changes in Medical Documentation over the Last Five Decades. | In medical documentation, standardized coding schemes are used to facilitate sharing, transformation and reusability of data. First, classification systems coding schemes have been introduced. While classification systems are mainly used for statistical purposes, individual care documentation moves towards the use of n... | ['Current Procedural Terminology', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Information Management', 'International Classification of Diseases', 'Medical Records Systems, Computerized', 'Medical Records, Problem-Oriented', 'Vocabulary, Controlled'] | 18,376,052 | [['L01.453.245.945.160'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.399'], ['L01.453.245.945.400'], ['E05.318.308.940.968.625', 'L01.313.500.750.300.695', 'N04.452.859.564.650', 'N05.715.360.300.715.500.530', 'N06.850.520.308.940.968.625'], ['E05.318.308.940.968.55... | ['Information Science [L]', 'Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Exposing the body--baring the soul. | It is often considered important that clothing should not be visible in a good medical photograph. Medical illustrators offer the clinical professionalism to allow most of their patients to feel comfortable being photographed. For some patients, however, consenting to medical photography involves more than a temporary ... | ['Autopsy', 'Culture', 'Human Body', 'Humans', 'Patient Rights', 'Photography', 'Religion'] | 12,150,030 | [['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['I01.076.201.450', 'I01.880.853.100'], ['I01.076.201.450.560', 'K01.093.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.473.650', 'N03.706.437.650'], ['E01.370.350.600', 'E05.712'], ['K01.844']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Expenditures on Complementary Health Approaches: United States, 2012. | OBJECTIVE: This report presents estimates of expenditures on complementary health approach use among the U.S. population. Estimates are presented for adults and children separately and combined, as well as stratified by type of approach and family income.METHODS: Combined data from 44,743 individuals aged 4 years and o... | ['Adolescent', 'Adult', 'Child', 'Complementary Therapies', 'Financing, Personal', 'Humans', 'Nutrition Surveys', 'United States', 'Young Adult'] | 27,352,222 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E02.190'], ['N03.219.559'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980.485', 'N05.715.360.300.800.469', 'N06.850.505.616', 'N06.850.520.308.980.469'], ['Z01.107.567.875'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Investigation of Saliva as an Alternative to Plasma Monitoring of Voriconazole. | BACKGROUND AND OBJECTIVES: Therapeutic drug monitoring (TDM) of voriconazole is increasingly being implemented in clinical practice. However, as blood sampling can be difficult in paediatric and ambulatory patients, a non-invasive technique for TDM is desirable. The aim of this study was to compare the pharmacokinetics... | ['Administration, Intravenous', 'Adult', 'Aged', 'Antifungal Agents', 'Aspergillosis', 'Drug Monitoring', 'Female', 'Humans', 'Male', 'Middle Aged', 'Saliva', 'Voriconazole'] | 25,910,879 | [['E02.319.267.082'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.136'], ['C01.150.703.080'], ['E01.370.520.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A12.200.666'], ['D03.383.129.799.950']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The neuronal reactions of the nucleus solitarius in response to stimulation of the gastric mechanoreceptors]. | Mechanical stimulation of the cat stomach revealed two groups of neuronal responses in the solitary tract's nucleus: phasic and tonic those. The neurons with phasic responses were found mainly in the caudal portion of the nucleus and could be regarded as representing stomach's mechanoreceptors. The neurons with tonic e... | ['Animals', 'Brain Mapping', 'Cats', 'Evoked Potentials', 'Mechanoreceptors', 'Medulla Oblongata', 'Microelectrodes', 'Neurons', 'Physical Stimulation', 'Stomach'] | 1,666,588 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['G07.265.216.500', 'G11.561.200.500'], ['A08.675.650.915.750', 'A08.800.950.750', 'A11.671.650.915.750'], ['A08.186.211.132.810.591.500'], ['E07.305.250.500'], ['A08.675', 'A11.671'... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of multisection CT angiography in the evaluation of vertebrobasilar vasospasm in patients with subarachnoid hemorrhage. | BACKGROUND AND PURPOSE: Optimal means for assessing cerebral vasospasm, mainly at the vertebrobasilar system, have not been established. The purpose of this study was to evaluate the role of multisection CT angiography (MCTA) in the detection and quantification of vertebrobasilar vasospasm (VBS) indicated on transcrani... | ['Adolescent', 'Adult', 'Aged', 'Basilar Artery', 'Blood Flow Velocity', 'Cerebral Angiography', 'Cerebral Hemorrhage, Traumatic', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Intracranial Arteriovenous Malformations', 'Male', 'Middle Aged', 'Postoperative Complications', 'R... | 15,502,127 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A07.015.114.106'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['C10.228.140.199.275.300', 'C10.228.140.300.53... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Search for association between suicide attempt and serotonergic polymorphisms. | Serotonergic neurotransmission has been implicated in suicidal behavior. Polymorphisms in the genes coding for tryptophan hydroxylase, serotonin receptor 2A and serotonin transporter were investigated in a sample of suicide attempters (n = 165) and healthy control subjects (n = 99). No significant differences were foun... | ['Adjustment Disorders', 'Alleles', 'Carrier Proteins', 'Depression', 'Europe', 'European Continental Ancestry Group', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Membrane Glycoproteins', 'Membrane Transport Proteins', 'Nerve Tissue Proteins', 'Odds Ratio', 'Personality Disorders', 'Polymorphism, Restri... | 10,909,124 | [['F03.950.500'], ['G05.360.340.024.340.030'], ['D12.776.157'], ['F01.145.126.350'], ['Z01.542'], ['M01.686.508.400'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.395.550', 'D12.776.543.550'], ['D12.776.157.530', 'D12.776.543.585'], ['D12.776.631'], ['... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Evaluation of IDI-MRDA assay on a collection of community-acquired methicillin-resistant Staphylococcus aureus isolates and on carriage specimens]. | UNLABELLED: The efficacy of infection control measures against MRSA is linked to the rapid detection of MRSA. With the conventional diagnosis by culture the response delays vary from 48 to 72 hours. In contrast molecular techniques give results within hours.OBJECTIVE: The objective of the present study is to perform th... | ['Culture Media', 'False Positive Reactions', 'Humans', 'Methicillin Resistance', 'Polymerase Chain Reaction', 'Predictive Value of Tests', 'Staphylococcal Infections', 'Staphylococcus aureus'] | 17,913,391 | [['D27.720.470.305', 'E07.206'], ['E01.354.506'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G06.099.225.500.600.525', 'G06.225.347.500.600.525', 'G07.690.773.984.269.347.500.600.525'], ['E05.393.620.500'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['C01.150.252.410.868'], [... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Coronary angiography by means of the percutaneous transbrachial approach. | A simplified method of coronary angiography was performed by means of the percutaneous transbrachial approach with a 5-F catheter designed for selective cannulation of the right and left coronary arteries. On 70 serial coronary angiograms, visualization of the coronary arteries was sufficient in all cases with no major... | ['Angiography', 'Brachial Artery', 'Catheterization, Peripheral', 'Coronary Angiography', 'Humans'] | 2,028,007 | [['E01.370.350.700.060', 'E01.370.370.050'], ['A07.015.114.139'], ['E02.148.224', 'E04.100.814.529.937', 'E04.502.382.937', 'E05.157.375'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A right atrial mass and a pseudomass. | Right atrial (RA) masses are rare entities often detected incidentally during imaging studies. Leading etiologies of right atrial masses are tumor, thrombi, and vegetations. We present two cases of right atrial masses, a cardiac lipoma and an artifact. Clinical and echocardiographic characteristics of benign cardiac tu... | ['Aged', 'Artifacts', 'Cardiac Surgical Procedures', 'Diagnosis, Differential', 'Echocardiography', 'Heart Neoplasms', 'Humans', 'Lipoma', 'Magnetic Resonance Imaging', 'Male'] | 15,901,299 | [['M01.060.116.100'], ['E05.047'], ['E04.100.376', 'E04.928.220'], ['E01.171'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C04.588.894.309', 'C14.280.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.550.400'], ['E01.370.350.825.500']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Clinical Value of Squamous Cell Carcinoma Antigen (SCCAg) in Anal Cancer - A Single-Center Retrospective Analysis. | AIM: To assess the clinical value of squamous cell carcinoma antigen (SCCAg) in anal cancer for chemoradiotherapy (CRT) patients.PATIENTS AND METHODS: In 24 patients with SCC of the anus, SCCAg was determined before CRT and at every follow-up visit.RESULTS: 16/24 (66.7%) had normal SCCAg and 11/16 (68.8%) achieved comp... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antigens, Neoplasm', 'Anus Neoplasms', 'Chemoradiotherapy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Retrospective Studies', 'Serpins'] | 27,272,844 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.050.285'], ['C04.588.274.476.411.307.790.040', 'C06.301.371.411.307.790.040', 'C06.405.249.411.307.790.040', 'C06.405.469.491.307.790.040', 'C06.405.469.860.101.163', 'C06.405.469.860.180.500.040'], ['E02.186.079', 'E02.319.164', 'E02.815.160'], ['B0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Heat denaturation of hemocytocardiotoxin from the venom of the Central Asian cobra]. | It has been stated that boiled for three hours haemocytocardiotoxin (HT) from cobra poison loses "direct" hemolytic activity and is unable to potentiate a haemolytic effect of phospholipase A. Surface activity of HT does not change. It is shown that in the course of heat denaturation the aggregation of toxin molecules ... | ['Animals', 'Cobra Cardiotoxin Proteins', 'Elapid Venoms', 'Hot Temperature', 'Luminescence', 'Phospholipases', 'Protein Denaturation'] | 911,899 | [['B01.050'], ['D12.776.831.222', 'D20.888.850.325.180', 'D23.946.833.850.325.180'], ['D20.888.850.325', 'D23.946.833.850.325'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G01.75... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Structural and functional aspects of Bufo americanus spermatozoa: effects of inactivation and reactivation. | Very little is known about the effects of manipulating toad sperm activity in vitro, and such information is important in the development of a genetic resource bank for bufonid species. The specific objectives of this study were to: 1). identify the optimal inactivation and reactivation solutions for toad spermatozoa c... | ['Animals', 'Bufonidae', 'Isotonic Solutions', 'Male', 'Mitochondria', "Ringer's Solution", 'Sperm Motility', 'Spermatozoa', 'Time Factors'] | 12,541,301 | [['B01.050'], ['B01.050.150.900.090.180.210'], ['D26.776.498'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D26.776.498.750'], ['E01.370.225.992.812', 'E05.200.992.812', 'G04.198.750'], ['A05.360.490.890', 'A11.497.760'], ['G01.910.857']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Suppression of plasma estrogen levels by letrozole and anastrozole is related to body mass index in patients with breast cancer. | PURPOSE: To investigate whether suppression of plasma estradiol and estrone sulfate levels by the aromatase inhibitors (AIs) anastrozole and letrozole is related to body mass index (BMI) in postmenopausal women with early estrogen receptor (ER) -positive breast cancer. Recent studies have reported that the AI anastrozo... | ['Aged', 'Aged, 80 and over', 'Anastrozole', 'Antineoplastic Agents, Hormonal', 'Aromatase Inhibitors', 'Body Mass Index', 'Breast Neoplasms', 'Estrogens', 'Estrone', 'Female', 'Humans', 'Letrozole', 'Middle Aged', 'Neoplasms, Hormone-Dependent', 'Nitriles', 'Postmenopause', 'Triazoles'] | 22,802,308 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D02.626.218', 'D03.383.129.799.275'], ['D27.505.954.248.169'], ['D27.505.519.389.870.300', 'D27.505.696.399.450.327.149', 'D27.505.696.399.450.855.300'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C04.588.180', 'C17.80... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The influence of sex hormones on anterior cruciate ligament rupture: female study. | PURPOSE: The purpose of this study was to determine the difference in the concentrations of testosterone, 17-â estradiol and progesterone between female patients with and without ACL rupture and the possible effect of these hormones on generalised joint laxity.METHODS: Female subjects with non-contact knee joint injury... | ['Adolescent', 'Adult', 'Anterior Cruciate Ligament', 'Anterior Cruciate Ligament Injuries', 'Athletic Injuries', 'Estradiol', 'Female', 'Follicular Phase', 'Gonadal Steroid Hormones', 'Humans', 'Joint Instability', 'Knee Injuries', 'Knee Joint', 'Menstrual Cycle', 'Progesterone', 'Risk Factors', 'Rupture', 'Saliva', '... | 24,832,697 | [['M01.060.057'], ['M01.060.116'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['C26.558.554.213'], ['C26.115'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G08.686.605.310'], ['D06.472.334.851'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['C26.558.554'], ['A... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization of the Oxygen Transmission Rate of Oak Wood Species Used in Cooperage. | The oxygen that wine receives while aged in barrels is of interest because it defines the reactions that occur during aging and, therefore, the final properties of the wine. This study is intended to make up for the lack of information concerning the oxygen permeability of eight different woods of Quercus alba L. and Q... | ['Food Packaging', 'Kinetics', 'Oxygen', 'Permeability', 'Quercus', 'Wine', 'Wood'] | 28,040,893 | [['J01.576.423.200.375', 'J01.576.423.850.600', 'J01.576.761.400'], ['G01.374.661', 'G02.111.490'], ['D01.268.185.550', 'D01.362.670'], ['G02.723'], ['B01.650.940.800.575.912.250.859.750.300.500'], ['G07.203.100.100.900', 'G07.203.200.887', 'J02.200.100.900', 'J02.350.887'], ['A18.450.500.500', 'J01.637.241.900']] | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Study of structural changes in chromatin in the presence of mono- and divalent cations by means of flow linear dichroism]. | The chromatin structure in solution was studied by the flow linear dichroism method (LD) in a wide range of ionic strengths. It was found that the increasing of the ionic strength from 0.25 mM EDTA, pH 7.0 to 100 mM NaCl leads to a manifold decrease of the LD amplitude of chromatin and inversion of the LD sign from neg... | ['Animals', 'Cations, Divalent', 'Cations, Monovalent', 'Cattle', 'Chromatin', 'Kinetics', 'Models, Structural', 'Osmolar Concentration', 'Spectrum Analysis', 'Thymus Gland'] | 7,144,752 | [['B01.050'], ['D01.248.497.300.333'], ['D01.248.497.300.459'], ['B01.050.150.900.649.313.500.380.271'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['G01.374.661', 'G02.111.490'], ['J01.897.280.500.545', 'L01.178.820.090.545'], ['G02.640'], ['E05.196.867'], ['A10.549.750', 'A15.382.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Nicotinic acid reduction of plasma volume loss after thermal trauma. | Intravenous administration of nicotinic acid to the anesthetized dog prior to thermal trauma reduced plasma loss at 10 minutes after burn from 7 milliliters per kilogram to less than 2 millimeters per kilogram. During the next 50 minutes plasma loss was the same in treated and untreated animals. An additional dose of n... | ['Animals', 'Burns', 'Capillary Permeability', 'Dogs', 'Fatty Acids, Nonesterified', 'Female', 'Male', 'Nicotinic Acids', 'Plasma Volume', 'Prostaglandins'] | 1,251,199 | [['B01.050'], ['C26.200'], ['G03.143.330', 'G09.330.165'], ['B01.050.150.900.649.313.750.250.216.200'], ['D10.251.310'], ['D03.066.515', 'D03.383.725.547'], ['G09.188.130.610', 'G09.330.380.092.610'], ['D10.251.355.255.550', 'D23.469.050.175.725']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of the Internal Bed Regulation Committees from hospitals of a Southern Brazilian city. | OBJECTIVE: To evaluate the composition of the Internal Regulation Committees created in hospitals of a capital city.METHODS: A cross-sectional descriptive study assessing the structure, processes and results of each Committee.RESULTS: The main reasons for implementing the committees were legal issues and overcrowding i... | ['Advisory Committees', 'Bed Occupancy', 'Brazil', 'Hospital Administration', 'Hospital Bed Capacity', 'Humans', 'Patient Admission'] | 29,091,157 | [['N03.706.742.500'], ['N02.278.050'], ['Z01.107.757.176'], ['H02.309', 'N02.278.216.500', 'N04.452.442.452'], ['N02.278.306.472'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.600', 'N02.421.585.400.600']] | ['Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Diagnostic accuracy of clinical examination and magnetic resonance imaging for common articular wrist pathology. | The authors retrospectively compared the diagnostic accuracy of clinical examination and magnetic resonance imaging for intra-articular wrist pathology (triangular fibrocartilage complex, lunotriquetral and scapholunate injuries), using wrist arthroscopy as the gold standard. Sixty-six patients had clinical examination... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Female', 'Humans', 'Joint Diseases', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Physical Examination', 'Sensitivity and Specificity', 'Wrist Joint', 'Young Adult'] | 24,205,765 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E01.370.600'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N0... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Upgrading the Gleason score in extended prostate biopsy: implications for treatment choice. | PURPOSE: To determine the incidence of overestimation of Gleason score (GS) in extended prostate biopsy, and consequently circumventing unnecessary aggressive treatment.METHODS AND MATERIALS: This is a retrospective study of 464 patients who underwent prostate biopsy and radical prostatectomy between January 2001 and N... | ['Adult', 'Aged', 'Biopsy, Needle', 'Chi-Square Distribution', 'Humans', 'Male', 'Middle Aged', 'Prostate', 'Prostatectomy', 'Prostatic Neoplasms', 'Regression Analysis', 'Retrospective Studies', 'Statistics, Nonparametric', 'Tumor Burden'] | 18,774,658 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effect of moderate weight loss on overnight growth hormone and cortisol secretion in healthy female volunteers. | The effects of moderate weight loss on overnight growth hormone and cortisol secretion were determined in 11 healthy women volunteers who lost an average of 3.1 kg in weight after undertaking a 1000-kcal diet for 3 weeks. There was a reduction in sleep-related growth hormone secretion and an increase in the value of th... | ['Adult', 'Circadian Rhythm', 'Diet, Reducing', 'Electroencephalography', 'Female', 'Growth Hormone', 'Humans', 'Hydrocortisone', 'Sleep Stages', 'Weight Loss'] | 2,522,119 | [['M01.060.116'], ['G07.180.562.190'], ['E02.642.249.285', 'G07.203.650.240.285'], ['E01.370.376.300', 'E01.370.405.245'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['F02... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
CpG island-mediated global gene regulatory modes in mouse embryonic stem cells. | Both transcriptional and epigenetic regulations are fundamental for the control of eukaryotic gene expression. Here we perform a compendium analysis of >200 large sequencing data sets to elucidate the regulatory logic of global gene expression programs in mouse embryonic stem (ES) cells. We define four major classes of... | ['Animals', 'Base Sequence', 'Cell Line', 'CpG Islands', 'DNA Methylation', 'DNA-Binding Proteins', 'Embryonic Stem Cells', 'Enhancer Elements, Genetic', 'Gene Expression Regulation', 'Genes, Regulator', 'Mice', 'Polycomb-Group Proteins', 'Promoter Regions, Genetic', 'Proto-Oncogene Proteins c-myc', 'Sequence Analysis,... | 25,405,324 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['D12.776.260'], ['A11.872.700.250'], ['G02.111.570.080.689.330', 'G05.360.080.689.33... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Assessment of neutrophil chemotaxis and random migration in children with thalassemia major. | Neutrophil chemotaxis and random migration were evaluated in 21 patients with thalassemia major and 21 healthy controls by a filter technique (Boyden chamber). Chemotactic and random migrations in patient group were found to be defective, which may partially account for the increased susceptibility to infection occasio... | ['Blood Transfusion', 'Cell Movement', 'Chemotaxis, Leukocyte', 'Child', 'Child, Preschool', 'Deferoxamine', 'Disease Susceptibility', 'Female', 'Ferritins', 'Humans', 'Iron', 'Male', 'Neutrophils', 'Reference Values', 'Siderophores', 'Splenectomy', 'Transferrin', 'beta-Thalassemia'] | 8,735,339 | [['E02.095.135'], ['G04.198', 'G07.568.500.180'], ['G04.198.424.233'], ['M01.060.406'], ['M01.060.406.448'], ['D02.092.570.394.265', 'D02.241.511.372.265'], ['C23.550.291.687', 'G07.100.250'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.412', 'D01.268.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Adenomatous polyposis coli influences micronuclei induction by PhIP and acrylamide in mouse erythrocytes. | Micronucleus (MN) induction in erythrocytes of multiple intestinal neoplasia (Min) mice with heterozygous Apc mutation was measured after s.c. injections of acrylamide, glycidamide, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and colchicine, and compared with wild-type (wt) mice. Since Apc influences microtu... | ['Acrylamide', 'Adenomatous Polyposis Coli', 'Adenomatous Polyposis Coli Protein', 'Animals', 'Colchicine', 'Cytarabine', 'DNA Adducts', 'Epoxy Compounds', 'Erythrocytes', 'Female', 'Flow Cytometry', 'Hydroxyurea', 'Imidazoles', 'Injections, Subcutaneous', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Mutant Strains', '... | 15,668,113 | [['D02.065.122.015', 'D02.241.081.069.094.015'], ['C04.557.470.035.215.100', 'C04.588.274.476.411.307.089', 'C04.700.100', 'C06.301.371.411.307.090', 'C06.405.249.411.307.090', 'C06.405.469.158.356.090', 'C06.405.469.491.307.090', 'C06.405.469.578.249', 'C16.320.700.100'], ['D05.500.117.249', 'D12.776.220.040', 'D12.77... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serum factors for opsonisation of non-typable Haemophilus influenzae. | Neutrophil chemiluminescence was used to assess the opsonins required for phagocytosis of non-typable Haemophilus influenzae isolated from sputum samples of patients with hypogammaglobulinaemia. Immunoglobulin was the major opsonin, whereas complement was relatively unimportant. Evidence was found for a heat-labile ops... | ['Agammaglobulinemia', 'Complement System Proteins', 'Fibronectins', 'Haemophilus influenzae', 'Humans', 'Immunoglobulin G', 'Luminescent Measurements', 'Neutrophils', 'Opsonin Proteins', 'Phagocytosis', 'Tuftsin', 'gamma-Globulins'] | 2,410,618 | [['C15.378.147.142', 'C15.604.515.032', 'C20.673.088'], ['D12.776.124.486.274'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776.543.550.350', 'D12.776.860.300.450'], ['B03.440.450.600.450.330', 'B03.660.250.550.290.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Archaeal Communities in a Heterogeneous Hypersaline-Alkaline Soil. | In this study the archaeal communities in extreme saline-alkaline soils of the former lake Texcoco, Mexico, with electrolytic conductivities (EC) ranging from 0.7 to 157.2 dS/m and pH from 8.5 to 10.5 were explored. Archaeal communities in the 0.7 dS/m pH 8.5 soil had the lowest alpha diversity values and were dominate... | ['Biodiversity', 'Cluster Analysis', 'DNA, Archaeal', 'Halobacteriaceae', 'Hydrogen-Ion Concentration', 'Mexico', 'Molecular Sequence Data', 'Phylogeny', 'Salinity', 'Sequence Analysis, DNA', 'Sequence Homology', 'Soil', 'Soil Microbiology'] | 26,074,731 | [['G16.500.275.157.049', 'N06.230.124.049'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['D13.444.308.180'], ['B02.200.400.400'], ['G02.300'], ['Z01.107.567.589'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G02.640.500'], ['E05.393.760.700'], ['G02.111.810', 'G05.810'], ['... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
The RhoA GTPase-activating protein DLC2 modulates RhoA activity and hyperalgesia to noxious thermal and inflammatory stimuli. | Deleted in liver cancer 2 (DLC2) is a novel Rho GTPase-activating protein that regulates RhoA activity. DLC2 is ubiquitously expressed in most tissues, including the brain, spinal cord and peripheral nerves, and is thought to be involved in actin cytoskeletal reorganization. Unlike DLC1-deficient mice, DLC2-deficient m... | ['Animals', 'Brain', 'GTPase-Activating Proteins', 'Hyperalgesia', 'Inflammation', 'MAP Kinase Signaling System', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Signal Transduction', 'Spinal Cord', 'Sural Nerve', 'Tumor Suppressor Proteins', 'rhoA GTP-Binding Protein'] | 22,204,965 | [['B01.050'], ['A08.186.211'], ['D12.644.360.325.150', 'D12.776.476.325.150'], ['C10.597.751.791.400', 'C23.888.592.763.770.400'], ['C23.550.470'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The evolution of portal hypertension surgery: lessons from 1000 operations and 50 Years' experience. | HYPOTHESIS: Surgery for portal hypertension has evolved widely in the past decades. Selection criteria and the type of operations have evolved because of the appearance of other therapeutic alternatives, such as pharmacotherapy, endoscopic therapy, transjugular intrahepatic portosystemic shunt, and liver transplantatio... | ['Gastrointestinal Hemorrhage', 'Humans', 'Hypertension, Portal', 'Portasystemic Shunt, Surgical', 'Retrospective Studies', 'Time Factors'] | 11,115,336 | [['C06.405.227', 'C23.550.414.788'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.494'], ['E04.035.760', 'E04.100.814.868.937'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Clinical features of patients bearing central nervous system hemangioblastoma in von Hippel-Lindau disease. | BACKGROUND: Central nervous system (CNS) hemangioblastoma (HB) is one of the most common manifestations in von Hippel-Lindau disease (VHL), but large-scale studies on clinical features of CNS HB in VHL are scarce.METHODS: On the basis of the results of a questionnaire, we collected data of VHL patients with CNS HB.RESU... | ['Adolescent', 'Adult', 'Age of Onset', 'Aged', 'Central Nervous System Neoplasms', 'Child', 'Cohort Studies', 'Female', 'Health Status Indicators', 'Hemangioblastoma', 'Humans', 'Male', 'Middle Aged', 'Quality of Life', 'Young Adult', 'von Hippel-Lindau Disease'] | 23,080,552 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.116.100'], ['C04.588.614.250', 'C10.551.240'], ['M01.060.406'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The autonomous innervation of the porcine testis in the period from birth to adulthood. | The innervation of the porcine testis was studied in 20 pigs, aged from 3 days to 2.5 years, and revealed remarkable changes in the period from birth to adulthood. Testes in piglets of 3 to 5 weeks have the most intense and most constant innervation, which reaches the gonad by three different routes: the funicular, cau... | ['Acetylcholinesterase', 'Aging', 'Animals', 'Animals, Newborn', 'Autonomic Nervous System', 'Calcitonin Gene-Related Peptide', 'Immunohistochemistry', 'Male', 'Neuropeptide Y', 'Neuropeptides', 'Substance P', 'Swine', 'Testis', 'Vasoactive Intestinal Peptide'] | 9,587,638 | [['D08.811.277.352.100.170.176'], ['G07.345.124'], ['B01.050'], ['B01.050.050.282'], ['A08.800.050'], ['D12.644.400.097', 'D12.776.631.650.097'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
HTLV-I-associated myelopathy associated with blood transfusion in the United States: epidemiologic and molecular evidence linking donor and recipient. | Six months after receiving 58 units of blood components, a 65-year-old white man from New York City, with no other risk factors for human T-lymphotropic virus type I (HTLV-I) infection, developed HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Investigation of blood donors identified a 25-year-old ... | ['Adult', 'Aged', 'Antibodies, Viral', 'Base Sequence', 'Blood Donors', 'Cloning, Molecular', 'Epidemiologic Methods', 'Female', 'Genes, Viral', 'Human T-lymphotropic virus 1', 'Humans', 'Male', 'Paraparesis, Tropical Spastic', 'Polymerase Chain Reaction', 'Probability', 'Transfusion Reaction', 'United States'] | 1,992,361 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['M01.898.313'], ['E05.393.220'], ['E05.318', 'N06.850.520'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Treatment of patients with advanced gastric carcinoma with the combination of etoposide plus oral tegafur modulated by uracil and leucovorin. A phase II study of the ONCOPAZ Cooperative Group. | BACKGROUND: Both the biochemical modulation and the continuous administration of 5-fluorouracil (5-FU) have achieved promising results in patients with gastric carcinoma. Conversely, several studies on gastric carcinoma have demonstrated that the combination of etoposide (VP-16), leucovorin (LV), and 5-FU (ELF) is effi... | ['Administration, Oral', 'Adult', 'Aged', 'Ambulatory Care', 'Anemia', 'Antidotes', 'Antimetabolites, Antineoplastic', 'Antineoplastic Agents, Phytogenic', 'Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma', 'Diarrhea', 'Drug Administration Schedule', 'Etoposide', 'Fluorouracil', 'Humans', 'Injections, Intra... | 8,673,994 | [['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['E02.760.106', 'N02.421.585.106'], ['C15.378.071'], ['D27.505.696.706.037', 'D27.720.799.037'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['D27.505.954.248.179'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.55... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cycloleucine (1-amino-cyclopentane carboxylic acid): tubular reabsorption and inhibitory effect on amino acid transport in the rat kidney. (Microperfusion experiments). | Renal tubular reabsorption of cycloleucine (1-amino-cyclopentane carboxylic acid) was studied in vivo et situ by continuous microperfusion of single proximal tubules of the rat. The results show: a) cycloleucine is reabsorbed rapidly compared with other amino acids b) this reabsorption is saturable and can be inhibited... | ['Absorption', 'Amino Acids', 'Animals', 'Antineoplastic Agents', 'Arginine', 'Biological Transport', 'Cell Membrane Permeability', 'Cyclopentanes', 'Glycine', 'Kidney Tubules, Proximal', 'Kinetics', 'Male', 'Oligomycins', 'Perfusion', 'Phenylalanine', 'Rats'] | 1,168,338 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['D12.125'], ['B01.050'], ['D27.505.954.248'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['G03.143'], ['G03.143.335', 'G04.175'], ['D02.455.426.392.368.450'], ['D12.125.481'], ['A05.810.453.736.560.570'], ['G01.374.661', 'G02.111.490... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Griscelli syndrome. | An eight month old male infant presented with recurrent infections and partial albinism. Initially a possibility of Chediak Higashi syndrome (CHS) was considered, but a negative investigative work up prompted us to look for an alternate diagnosis. A literature search revealed that Griscelli syndrome (GS) has overlappin... | ['Chediak-Higashi Syndrome', 'Diagnosis, Differential', 'Hepatomegaly', 'Humans', 'Immunologic Deficiency Syndromes', 'Infant', 'Male', 'Pancytopenia', 'Piebaldism', 'Splenomegaly'] | 15,053,385 | [['C11.270.040.772', 'C15.378.553.774.257', 'C16.320.798.375', 'C20.673.774.257', 'C20.673.795.375'], ['E01.171'], ['C06.552.416', 'C23.300.775.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.673'], ['M01.060.703'], ['C15.378.700'], ['C16.320.290.040.600', 'C16.320.565.100.102.600', 'C16.320.850.080.600',... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A reversibly unfolding fragment of P22 tailspike protein with native structure: the isolated beta-helix domain. | The homotrimeric tailspike endorhamnosidase of phage P22 has been used to compare in vivo and in vitro folding pathways and the influence of single amino acid substitutions thereon. Its main structural motif, which contains the known folding mutation sites, consists of three large right-handed parallel beta-helices. A ... | ['Bacteriophage P22', 'Circular Dichroism', 'Glycoside Hydrolases', 'Kinetics', 'Models, Molecular', 'O Antigens', 'Oligosaccharides', 'Peptide Fragments', 'Protein Folding', 'Protein Structure, Secondary', 'Protein Structure, Tertiary', 'Receptors, Virus', 'Recombinant Proteins', 'Spectrometry, Fluorescence', 'Ultrace... | 9,636,063 | [['B04.123.150.700.070', 'B04.123.706.070', 'B04.280.090.700.070'], ['E05.196.867.151'], ['D08.811.277.450'], ['G01.374.661', 'G02.111.490'], ['E05.599.595'], ['D09.698.718.450.600', 'D10.494.600', 'D23.050.161.616.525.600', 'D23.946.123.329.500.600'], ['D09.698.629'], ['D12.644.541'], ['G01.154.651', 'G02.111.688'], [... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Repetitive Behaviors in Frontotemporal Dementia: Compulsions or Impulsions? | OBJECTIVE: The presence of repetitive behaviors is one of the core criteria for behavioral variant frontotemporal dementia (bvFTD). Patients with bvFTD often have perseverative, stereotyped, or compulsive-ritualistic behavior as an early aspect of their disorder. It is unclear whether such behaviors are related to comp... | ['Aged', 'Compulsive Behavior', 'Female', 'Frontotemporal Dementia', 'Hoarding', 'Humans', 'Male', 'Middle Aged', 'Obsessive-Compulsive Disorder', 'Retrospective Studies', 'Stereotyped Behavior'] | 30,537,913 | [['M01.060.116.100'], ['F01.145.527.100'], ['C10.228.140.380.266.299', 'C10.574.950.300.299', 'C18.452.845.800.300.299', 'F03.615.400.380.299'], ['F01.145.493'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F03.080.600'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Microwave resonance therapy in the combined treatment of gastric polyposis]. | A study of 70 patients with polyps and polyposis of the stomach indicates that the use of microwave electromagnetic radiation of low intensity associated with polypectomy increases significantly the treatment and improves the immediate and long-term results. Microwave resonance therapy possesses a regulating action, no... | ['Adult', 'Aged', 'Combined Modality Therapy', 'Electrosurgery', 'Female', 'Gastroscopy', 'Histocytochemistry', 'Humans', 'Lymphocytes', 'Male', 'Microwaves', 'Middle Aged', 'Polyps', 'Stomach Neoplasms'] | 2,330,701 | [['M01.060.116'], ['M01.060.116.100'], ['E02.186'], ['E04.262'], ['E01.370.372.250.250.325', 'E01.370.388.250.250.250.320', 'E04.210.240.250.320', 'E04.502.250.250.250.320'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Current status of hematopoietic stem cell transplantation in Taiwan. | In Taiwan, hematopoietic SCT (HSCT) has been used to treat patients with hematological diseases since 1983. Since then, more than 2200 patients have undergone HSCT in 15 large hospitals. The disease entities included acute leukemia in 37% of cases, non-Hodgkin's lymphoma in 26%, CML in 10%, multiple myeloma in 7% and s... | ['Graft vs Host Disease', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Taiwan', 'Tissue Donors'] | 18,724,286 | [['C20.452'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.872', 'Z01.639.850'], ['M01.898']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Assessing the renal toxicity of Capstone depleted uranium oxides and other uranium compounds. | The primary target for uranium toxicity is the kidney. The most frequently used guideline for uranium kidney burdens is the International Commission on Radiological Protection value of 3 microg U g(-1) kidney, a value that is based largely upon chronic studies in animals. In the present effort, a risk model equation wa... | ['Aerosols', 'Air Pollution, Radioactive', 'Algorithms', 'Beta Particles', 'Computer Simulation', 'Firearms', 'Gulf War', 'Humans', 'Incidence', 'Kidney Diseases', 'Military Personnel', 'Occupational Exposure', 'Oxides', 'Radiation Injuries', 'Radiation Monitoring', 'Radioactive Waste', 'Risk Assessment', 'Risk Factors... | 19,204,490 | [['D20.280.055', 'D26.255.165.055'], ['N06.850.460.100.110', 'N06.850.810.080'], ['G17.035', 'L01.224.050'], ['G01.750.750.125'], ['L01.224.160'], ['J01.637.870.350'], ['I01.880.735.950.250.657', 'K01.400.504.968.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', ... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]',... | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Efficacy and safety of standardized extract of Trigonella foenum-graecum L seeds as an adjuvant to L-Dopa in the management of patients with Parkinson's disease. | The objective of this study is to evaluate disease modifying efficacy and safety of a standardized extract of Trigonella foenum-graecum L, Fenugreek (IBHB) (family Fabaceae) as a nutritional adjuvant to Levo-dopa (L-Dopa) in Parkinson's disease (PD) patients. We conducted double-blind placebo-controlled proof of concep... | ['Adjuvants, Pharmaceutic', 'Aged', 'Dihydroxyphenylalanine', 'Double-Blind Method', 'Female', 'Humans', 'Levodopa', 'Male', 'Middle Aged', 'Parkinson Disease', 'Plant Extracts', 'Seeds', 'Trigonella'] | 23,512,705 | [['D26.650.064', 'D27.720.744.064'], ['M01.060.116.100'], ['D02.092.311.200', 'D02.455.426.559.389.657.166.175.200', 'D12.125.072.050.685.400', 'D12.125.072.050.875.130'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.311... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Early anti-inflammatory intervention ameliorates axial disease in the proteoglycan-induced spondylitis mouse model of ankylosing spondylitis. | BACKGROUND: Ankylosing spondylitis (AS) is characterised by immune-mediated arthritis and osteoproliferation, ultimately leading to joint ankylosis. Whether inflammation is necessary for osteoproliferation is controversial, fuelled by the unclear efficacy of anti-inflammatory treatments on radiographic progression. In ... | ['Animals', 'Anti-Inflammatory Agents', 'Disease Models, Animal', 'Drug Administration Schedule', 'Drug Therapy, Combination', 'Etanercept', 'Female', 'Humans', 'Mice', 'Mice, Inbred BALB C', 'Prednisolone', 'Proteoglycans', 'Spondylitis, Ankylosing'] | 28,558,827 | [['B01.050'], ['D27.505.954.158'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.319.283'], ['E02.319.310'], ['D12.644.541.500.697.624', 'D12.776.124.486.485.538.500.624', 'D12.776.124.486.485.680.697.624', 'D12.776.124.790.651.538.500.624', 'D12.776.124.790.651.680.660.624', 'D12.776.377.715.548.538.500.624', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Oxidation behavior and kinetics of representative VOCs emitted from petrochemical industry over CuCeOx composite oxides]. | CuCeOx composite catalysts were synthesized via coprecipitation (COP-CuCeO,) and incipient impregnation (IMP-CuCeOx) methods, respectively. The physicochemical properties of the samples were characterized by XRD, low-temperature N2 sorption, H2-TPR and O2-TPD. The influences of reactant composition and concentration, r... | ['Air Pollutants', 'Benzene', 'Catalysis', 'Extraction and Processing Industry', 'Hexanes', 'Kinetics', 'Models, Chemical', 'Oxidation-Reduction', 'Oxides', 'Petroleum', 'Toluene', 'Volatile Organic Compounds'] | 24,640,915 | [['D27.888.284.101'], ['D02.455.426.559.389.023'], ['G02.130'], ['J01.576.655.875'], ['D02.455.326.146.500'], ['G01.374.661', 'G02.111.490'], ['E05.599.495'], ['G02.700', 'G03.295.531'], ['D01.248.497.158.685', 'D01.650.550'], ['D20.345.630', 'N06.230.132.258.630'], ['D02.455.426.559.389.832'], ['D02.974']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The effect of synthetic peptides corresponding to Fc sequences in human IgG1 on various steps in the B cell activation pathway. | The influence of synthetic peptides comprising sequences in the exposed positions of the Fc region of human IgG 1 was tested on B lymphocyte activation. CH 2 domain peptides having an inhibitory effect on antibody-dependent cellular cytotoxicity, as well as the whole Fc fragment, induced the appearance of the early sig... | ['Amino Acid Sequence', 'B-Lymphocytes', 'HLA-DR Antigens', 'Humans', 'Immunoglobulin Fc Fragments', 'Immunoglobulin G', 'Immunoglobulin M', 'Leukocyte Migration-Inhibitory Factors', 'Lymphocyte Activation', 'Molecular Sequence Data', 'Peptides', 'Pokeweed Mitogens', 'Thymidine'] | 3,280,328 | [['G02.111.570.060', 'L01.453.245.667.060'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D12.776.395.550.509.400.440', 'D12.776.543.550.440.400.440', 'D23.050.301.500.400.400.440', 'D23.050.301.500.450.400.440', 'D23.050.705.552.410.400.440'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Can Positron Emission Tomography and Computed Tomography Be a Substitute for Bone Marrow Biopsy in Detection of Bone Marrow Involvement in Patients with Hodgkin's or Non-Hodgkin's Lymphoma? | INTRODUCTION: Positron emission tomography and computed tomography (PET/CT) has become an important part of staging and treatment evaluation algorithms of lymphoma. We aimed to compare the results of PET/CT with bone marrow biopsy (BMB) with respect to bone marrow involvement (BMI) in patients with Hodgkin's lymphoma (... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Biopsy', 'Bone Marrow', 'Bone Marrow Examination', 'Female', 'Hodgkin Disease', 'Humans', 'Lymphoma, Non-Hodgkin', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Positron Emission Tomography Computed Tomography', 'Reproducibility of Results', 'Retrospective Studies', '... | 25,912,844 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A15.382.216'], ['E01.370.225.625.135', 'E05.200.625.135'], ['C04.557.386.355', 'C15.604.515.56... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Transthoracic approach in surgery of the kidneys]. | Under analysis were clinical observations of 37 patients who were subjected to transthoracal nephrectomy. Positive sides and advantages of transthoracal nephrectomies were noted. Preliminary embolization of the arterial bed of the kidney was shown to be not expedient in the surgical procedure in question. It is emphasi... | ['Diaphragm', 'Humans', 'Intercostal Muscles', 'Kidney Diseases', 'Nephrectomy', 'Postoperative Care', 'Suture Techniques'] | 3,068,884 | [['A02.633.567.900.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.567.900.500'], ['C12.777.419', 'C13.351.968.419'], ['E04.950.774.435'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.722.700'], ['E04.987.775']] | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Universal and rapid salt-extraction of high quality genomic DNA for PCR-based techniques. | A very simple, fast, universally applicable and reproducible method to extract high quality megabase genomic DNA from different organisms is described. We applied the same method to extract high quality complex genomic DNA from different tissues (wheat, barley, potato, beans, pear and almond leaves as well as fungi, in... | ['Animals', 'DNA', 'DNA, Plant', 'Decapoda', 'Grasshoppers', 'Polymerase Chain Reaction', 'Sodium Chloride', 'Time Factors'] | 9,358,185 | [['B01.050'], ['D13.444.308'], ['D13.444.308.435'], ['B01.050.500.131.365.190'], ['B01.050.500.131.617.678.369'], ['E05.393.620.500'], ['D01.210.450.150.875', 'D01.857.650'], ['G01.910.857']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Muscle-bone characteristics in children with Prader-Willi syndrome. | BACKGROUND: A decrease in muscle mass, low motor performance, and normal lumbar spine bone mineral density (BMD) have been reported in children with Prader-Willi syndrome (PWS). However, these data are limited by the fact that PWS children (who have short stature) were compared to age-matched healthy or obese individua... | ['Absorptiometry, Photon', 'Adolescent', 'Body Height', 'Bone Density', 'Bone and Bones', 'Case-Control Studies', 'Child', 'Exercise Test', 'Female', 'Humans', 'Male', 'Motor Activity', 'Muscle, Skeletal', 'Organ Size', 'Prader-Willi Syndrome'] | 22,162,467 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.057'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['G11.427.100'], ['A02.835.232', 'A10.165.265'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['E01.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Long-term sequelae of malignant tumors in childhood: consequences of late side-effects]. | 110 children with malignant diseases (leukemia excepted) who survived 5-20 years (median 9) post-therapy were followed (1996-1998). Median age during follow-up was 15 years (range 5-23). The most common malignancies were brain tumors, lymphoma, retinoblastoma and Wilm's tumor. The 174 late side-effects included endocri... | ['Adolescent', 'Adult', 'Antineoplastic Agents', 'Brain Neoplasms', 'Child', 'Child, Preschool', 'Eye Neoplasms', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Kidney Neoplasms', 'Lymphoma', 'Male', 'Mental Disorders', 'Neoplasms', 'Nervous System Diseases', 'Radiotherapy', 'Retinoblastoma', 'Survivors', 'Time Fa... | 11,242,936 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.248'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['M01.060.406'], ['M01.060.406.448'], ['C04.588.364', 'C11.319'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The role of peritoneoscopy (laparoscopy) in the evaluation of the acute abdomen in critically ill patients. | Emergency peritoneoscopy (laparoscopy) to evaluate a suspected intraabdominal catastrophe was performed in ten critically ill patients over a 3-year period. The examination was negative in six cases, thereby avoiding celiotomy in this high-risk group. The examination was positive in four cases and, on this basis, celio... | ['Abdomen, Acute', 'Aged', 'Emergencies', 'Female', 'Humans', 'Laparoscopy', 'Male', 'Middle Aged'] | 1,465,726 | [['C23.888.592.612.054.200', 'C23.888.821.030.249'], ['M01.060.116.100'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630']] | ['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Depletion of B cells induces remission of autoimmune hepatitis in mice through reduced antigen presentation and help to T cells. | UNLABELLED: Autoimmune hepatitis (AIH) is known as a T cell-mediated disease. However, AIH patients refractory to conventional treatment have been successfully treated with anti-CD20-mediated B-cell depletion. The aim of this project was to understand the immunological changes underlying the AIH remission caused by B-c... | ['Animals', 'Antigen Presentation', 'Antigens, CD20', 'Autoantigens', 'B-Lymphocytes', 'Cytokines', 'Hepatitis, Autoimmune', 'Lymphocyte Activation', 'Lymphocyte Depletion', 'Mice', 'Mice, Inbred C57BL', 'T-Lymphocytes'] | 26,175,263 | [['B01.050'], ['G12.119', 'G12.450.050.400.070'], ['D23.050.301.264.035.120', 'D23.050.301.264.051.120', 'D23.101.100.110.120', 'D23.101.100.150.120'], ['D23.050.422'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D12.644.276.374', 'D12.776.4... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The theoretical limits of watermark spread spectrum sequence. | At present, the spread spectrum (SS) sequences used in watermark include i.i.d. random sequences and the sequences used in SS communications. They appear earlier than digital watermark. Almost no researchers pay attention to whether they are really fit for watermark. In this paper, we compare the SS watermark channel a... | ['Algorithms', 'Models, Theoretical'] | 24,790,566 | [['G17.035', 'L01.224.050'], ['E05.599']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Two methods for determining erucic acid in edible fats and oils: results from a collaborative study on a rapid, open-tubular (capillary) GLC method and comparison with an isolation TLC procedure. | The results of an international collaborative study for the determination of 5% erucic acid in four samples of edible fats and oils with differing levels of 22:1 isomers other than erucic acid, based on the use of wall-coated (SILAR-5CP) open-tubular gas-liquid chromatography, are examined. The same samples had been an... | ['Autoanalysis', 'Chemical Phenomena', 'Chemistry', 'Chromatography, Gas', 'Chromatography, Thin Layer', 'Dietary Fats', 'Erucic Acids', 'Fatty Acids, Unsaturated', 'Oils'] | 6,833,445 | [['E05.059'], ['G02'], ['H01.181'], ['E05.196.181.349'], ['E05.196.181.400.537'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D10.251.355.325.300'], ['D10.251.355'], ['D10.627']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Prevention of infantile spasms relapse: Zonisamide and topiramate provide no benefit. | OBJECTIVE: There is scant evidence to guide the management of infantile spasms after successful response to initial therapies. There is significant risk of relapse, largely because effective pharmacologic treatments cannot be continued long term because of concern for significant adverse events. Zonisamide (ZNS) and to... | ['Cohort Studies', 'Electroencephalography', 'Female', 'Fructose', 'Humans', 'Infant', 'Isoxazoles', 'Male', 'Recurrence', 'Spasms, Infantile', 'Statistics, Nonparametric', 'Survival Analysis', 'Topiramate', 'Video Recording', 'Vigabatrin', 'Zonisamide'] | 27,312,124 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.376.300', 'E01.370.405.245'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D03.383.129.385'], ['C23.550.291.937'], ['C10.228.140.490.375.760', 'C10.228.140.490... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Content of gentiopicroside and loganic acid in Radix gentianae and their fingerprints]. | To develop a HPLC-DAD-ESI-TOF/MS analysis method for the determination of gentiopicroside and loganic acid in Radix gentianae samples and for the research of their fingerprints. The samples were extracted using ASE for 10 min under 100 degrees C and 9.65 MPa, and divided into water phase and chloroform phase and analyz... | ['Chromatography, High Pressure Liquid', 'Ecosystem', 'Gentiana', 'Glucosides', 'Iridoid Glucosides', 'Iridoids', 'Plant Roots', 'Plants, Medicinal', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Spectrometry, Mass, Electrospray Ionization'] | 17,703,785 | [['E05.196.181.400.300'], ['G16.500.275.157', 'N06.230.124'], ['B01.650.940.800.575.912.250.456.750.391'], ['D09.408.348'], ['D02.455.426.392.368.450.675.500.500.500', 'D02.455.849.575.188.500.500.500', 'D03.383.663.491.500.500', 'D09.408.348.387', 'D09.408.423.500'], ['D02.455.426.392.368.450.675.500', 'D02.455.849.57... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The auricular myocardiocytes of the heart constitute an endocrine organ. Characterization of a porcine cardiac peptide hormone, cardiodilatin-126. | A peptide hormone was extracted from the porcine right atrium following a bioassay for differential vasorelaxant effects on smooth muscle strips from aorta and renal and inferior mesenteric arteries. The isolation procedure included several steps of gel-permeation and ion-exchange chromatography, and high performance l... | ['Amino Acid Sequence', 'Animals', 'Aorta', 'Atrial Natriuretic Factor', 'Chromatography, High Pressure Liquid', 'Endocrine Glands', 'Glomerular Filtration Rate', 'Heart Atria', 'Kidney', 'Mesenteric Arteries', 'Microscopy, Electron', 'Muscle Proteins', 'Myocardium', 'Swine', 'Vasodilation'] | 6,549,270 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A07.015.114.056'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['E05.196.181.400.300'], ['A06.300'], ['E01.370.390.400.300', 'G08.852.357'], ['A07.541.358'], ['A05.810.453'], ['A07.015.114.565'], ['E01.370.350.515.402', 'E05.595.402'], ['D12.776.210.500'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Clinical characteristics and survival of patients with surgically resected, incidentally detected lung cancer. | BACKGROUND: There is little information on the clinical characteristics and outcomes of patients with surgically resected, incidentally detected lung cancers. Our hypothesis was that among patients with surgically resected non-small cell lung cancer (NSCLC), incidentally detected cancers were common, were less likely t... | ['Carcinoma, Non-Small-Cell Lung', 'Humans', 'Incidental Findings', 'Lung Neoplasms', 'Survival Analysis'] | 17,410,027 | [['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.410'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E05.318.740.998', 'N05.715.360.750.795', 'N06.850.520.830.998']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of community-based HIV counselling and testing (CBCT) through index client tracing and other modalities: Outcomes in 13 South African high HIV prevalence districts by gender and age. | BACKGROUND: To increase HIV case finding in a Community-based HIV counselling and testing (CBCT) programme, an index client tracing modality was implemented to target index clients' sexual network and household members.OBJECTIVE: To compare index client tracing modality's outcomes with other CBCT recruitment modalities... | ['Adolescent', 'Adult', 'Age Distribution', 'Child', 'Child, Preschool', 'Counseling', 'Female', 'HIV Infections', 'Humans', 'Infant', 'Male', 'Mass Screening', 'Middle Aged', 'Prevalence', 'Residence Characteristics', 'Sex Distribution', 'Young Adult'] | 31,490,938 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.406'], ['M01.060.406.448'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480']... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
DNA microstructure based on self-assembly of 4-sticky-end Holliday junctions in aqueous solution. | Liverwort-like DNA microscale structures consist of 4-sticky-end Holiday junctions as DNA bricks that can be used in nanotechnology and nanobiotechnology to direct the self-assembly of nanomachines as well as DNA assembly. Previously it has not been possible to obtain such DNA microscale structural forms, but herein we... | ['Base Sequence', 'DNA, Cruciform', 'Microscopy, Atomic Force', 'Microscopy, Confocal', 'Nanostructures', 'Nanotechnology', 'Solutions', 'Spectrometry, Fluorescence', 'Water'] | 17,450,823 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.295', 'G02.111.570.820.486.325', 'G05.360.580.325'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['E01.370.350.515.395', 'E05.595.395'], ['J01.637.512'], ['H01.603', 'J01.897.520.600'], ['D26.776'], ['E05.196.712.516.600.676', 'E05.196.867.72... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Deoxyribonucleic acid strand breaks during drying of Escherichia coli on a hydorohobic filter membrane. | Cells of Escherichia coli mounted on a hydrophobic filter membrane were dried under various vapor pressures. A mutant defective in deoxyribonucleic acid repair (uvrA recA) was more sensitive to drying at a water activity of 0.53 or below than the parent strain but not at a water activity of 0.75 and above. Sucrose grad... | ['DNA Repair', 'DNA, Bacterial', 'Desiccation', 'Escherichia coli', 'Micropore Filters', 'Mutation', 'Nucleic Acid Denaturation', 'Water'] | 373,625 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Absolute bioavailability of theophylline (Euphylline)]. | The pharmacokinetics and bioavailability of theophylline have been investigated in eight healthy subjects following application of the drug in form of a tablet, a retard tablet (enteric-coated), and a suppository (Euphyllin) in comparison with an intravenous preparation. Peak plasma concentrations were measured 1.5 hou... | ['Adult', 'Biological Availability', 'Delayed-Action Preparations', 'Drug Evaluation', 'Female', 'Half-Life', 'Humans', 'Male', 'Suppositories', 'Tablets', 'Theophylline'] | 7,450,653 | [['M01.060.116'], ['G03.787.151', 'G07.690.725.129'], ['D26.255.210', 'E02.319.300.253'], ['E05.290.625', 'E05.337.425'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.255.785'], ['D26.255.830'], ['D03.132.960.751', 'D03.633.100.759.758.824.751']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An analogue of piperonyl butoxide facilitates the characterisation of metabolic resistance. | BACKGROUND: Previous work has demonstrated that piperonyl butoxide (PBO) not only inhibits microsomal oxidases but also resistance-associated esterases. The ability to inhibit both major metabolic resistance enzymes makes it an ideal synergist to enhance xenobiotics but negates the ability to differentiate which enzyme... | ['Animals', 'Enzyme Inhibitors', 'Esterases', 'Hemiptera', 'Insect Proteins', 'Insecticide Resistance', 'Pesticide Synergists', 'Piperonyl Butoxide'] | 18,951,417 | [['B01.050'], ['D27.505.519.389'], ['D08.811.277.352'], ['B01.050.500.131.617.412'], ['D12.776.093.500'], ['G07.690.773.984.491'], ['D27.720.031.700.748', 'D27.888.723.748'], ['D03.383.246.118.600', 'D03.633.100.115.600']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hypophosphatasia: validation and expansion of the clinical nosology for children from 25 years experience with 173 pediatric patients. | Hypophosphatasia (HPP) is caused by loss-of-function mutation(s) within the gene TNSALP that encodes the "tissue-nonspecific" isoenzyme of alkaline phosphatase (TNSALP). In HPP, inorganic pyrophosphate, an inhibitor of mineralization and substrate for TNSALP, accumulates extracellularly often leading to rickets or oste... | ['Adolescent', 'Alkaline Phosphatase', 'Child', 'Child, Preschool', 'DNA Mutational Analysis', 'Female', 'Humans', 'Hypophosphatasia', 'Infant', 'Male', 'Mutation', 'Young Adult'] | 25,731,960 | [['M01.060.057'], ['D08.811.277.352.650.035'], ['M01.060.406'], ['M01.060.406.448'], ['E05.393.760.700.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.320.565.618.482', 'C18.452.648.618.482'], ['M01.060.703'], ['G05.365.590'], ['M01.060.116.815']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Effect of lactobacillus immunotherapy on genital infections in women (Solco Trichovac/Gynatren)]. | In view of the high cure rates of Trichomonas vaginitis after vaccination with the immunotherapeutic drug Solco Trichovac Gynatren, the therapeutic efficacy of this regimen in nonspecific vaginitis was investigated. 94 patients were treated in a multicentre study. Concurrent with a decrease of pathogens, the growth of ... | ['Adult', 'Aged', 'Bacterial Vaccines', 'Female', 'Humans', 'Hydrogen-Ion Concentration', 'Immunotherapy', 'Lactobacillus', 'Middle Aged', 'Vaginitis'] | 6,565,612 | [['M01.060.116'], ['M01.060.116.100'], ['D20.215.894.135'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E02.095.465.425'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475', 'B03.510.550.450.475'], ['M01.060.116.630'], ['C13.351.500.894.906']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Carotid artery stiffness in patients with end-stage renal disease: no effect of long-term homocysteine-lowering therapy. | BACKGROUND: The excess of cardiovascular disease in end-stage renal disease (ESRD) patients is unexplained, but could relate to altered intrinsic vascular wall properties, such as increased arterial stiffness, which could be mediated by hyperhomocysteinemia. We investigated potential determinants of carotid artery stif... | ['Age Factors', 'Analysis of Variance', 'Biomarkers', 'Blood Pressure', 'Brachial Artery', 'Carotid Artery, Common', 'Compliance', 'Endothelins', 'Homocysteine', 'Humans', 'Kidney Failure, Chronic', 'Pyridoxine', 'Regression Analysis', 'Renal Dialysis', 'Vasodilation', 'Vitamin B 12', 'von Willebrand Factor'] | 10,661,480 | [['N05.715.350.075', 'N06.850.490.250'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D23.101'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07.015.114.139'], ['A07.015.114.186.200'], ['G01.374.590.210'], ['D12.644.276.400', 'D12.776.467.400', 'D23.529.400'], ['D02.886.030.498', 'D12.125.166.... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Quinolinic acid-induced lesions of the rat striatum: quantitative autoradiographic binding assessment. | Injection of the excitatory amino-acid analog quinolinic acid into the striatum of rats produces neuropathological and neurochemical alterations that are reminiscent of those observed in Huntington's disease. In the present study, we evaluated quinolinic acid-induced striatal changes using quantitative autoradiographic... | ['Animals', 'Autoradiography', 'Benzazepines', 'Binding, Competitive', 'Cholinergic Agents', 'Corpus Striatum', 'Disease Models, Animal', 'Dizocilpine Maleate', 'Dopamine Antagonists', 'Dopamine Uptake Inhibitors', 'Excitatory Amino Acid Antagonists', 'Hemicholinium 3', 'Huntington Disease', 'Isoquinolines', 'Male', 'M... | 9,471,103 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['D03.633.100.079'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D27.505.519.625.120', 'D27.505.696.577.120'], ['A08.186.211.200.885.287.249.487'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.455.426.559.847.181.384.380', 'D0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Fibrous bone dysplasia and ossifying bone fibroma in the orbital and periorbital region with special reference to CT]. | Fibro-osseous conditions affecting the craniofacial bones pose a complex diagnostic problem. Differentiation between monostotic fibrous dysplasia (FD) and ossifying fibroma (OF) is only possible by correlation of clinical, radiographical and histopathological features. CT was superior to conventional radiography/polyto... | ['Adolescent', 'Adult', 'Child', 'Female', 'Fibroma', 'Fibrous Dysplasia of Bone', 'Humans', 'Male', 'Neoplasm Recurrence, Local', 'Orbital Neoplasms', 'Ossification, Heterotopic', 'Osteoma', 'Skull Neoplasms', 'Tomography, X-Ray Computed'] | 2,999,897 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['C04.557.450.565.590.340'], ['C05.116.099.708.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.655', 'C23.550.727.655'], ['C04.588.149.721.656', 'C04.588.364.659', 'C05.116.231.754.659', 'C11.319.457', 'C11.675.659'], ['C23.550.751'], ['C04.557.450.5... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Late Glacial Demographic Expansion Motivates a Clock Overhaul for Population Genetics. | The molecular clock hypothesis is fundamental in evolutionary biology as by assuming constancy of the molecular rate it provides a timeframe for evolution. However, increasing evidence shows time dependence of inferred molecular rates with inflated values obtained using recent calibrations. As recent demographic calibr... | ['Climate Change', 'Evolution, Molecular', 'Genetics, Population', 'Phylogeny', 'Population Dynamics', 'Time Factors'] | 26,683,588 | [['G16.500.175.374'], ['G05.045.250', 'G16.075.250'], ['H01.158.273.343.335'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['G01.910.857']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Bis-(3'-5')-cyclic dimeric GMP regulates antimicrobial peptide resistance in Pseudomonas aeruginosa. | Bis-(3'-5')-cyclic dimeric GMP (c-di-GMP) is an intracellular second messenger that controls the lifestyles of many bacteria. A high intracellular level of c-di-GMP induces a biofilm lifestyle, whereas a low intracellular level of c-di-GMP stimulates dispersal of biofilms and promotes a planktonic lifestyle. Here, we u... | ['Anti-Bacterial Agents', 'Bacterial Proteins', 'Biofilms', 'Colistin', 'Cyclic GMP', 'Drug Resistance, Bacterial', 'Gene Expression Profiling', 'Gene Expression Regulation, Bacterial', 'Genes, Reporter', 'Green Fluorescent Proteins', 'Plankton', 'Proteomics', 'Pseudomonas aeruginosa', 'Second Messenger Systems'] | 23,403,434 | [['D27.505.954.122.085'], ['D12.776.097'], ['A20.593', 'G06.120'], ['D04.345.566.780.110', 'D10.477.750.110', 'D12.644.050.600.110', 'D12.644.641.780.110', 'D12.776.543.695.054.600.110'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['G06.099.225', 'G06.225.347', 'G0... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Hypsilara breweri n.sp. from Venezuela: description of new species with notes on the morphology and phylogenetic relationships of the genus (Coleoptera: Elmidae: Larainae). | A new species of the genus Hypsilara Maier & Spangler, 2011, collected in the Eastern Venezuela, is described and illustrated. We provide habitus photographs, detail drawings of both male and female genitalia, and description of some morphological features, which were omitted in the description of the genus. Included a... | ['Animal Distribution', 'Animals', 'Coleoptera', 'Female', 'Male', 'Phylogeny', 'Species Specificity', 'Venezuela'] | 26,097,972 | [['F01.145.113.069', 'G16.049'], ['B01.050'], ['B01.050.500.131.617.720.500.500.375'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G16.824'], ['Z01.107.757.943']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Effects of dietary Mn-methionine supplementation on the egg quality of laying hens. | This study was conducted to investigate the effects of dietary manganese-methionine (Mn-Met) supplementation on the egg quality of laying hens. A total of 480 Jinghong-1 strain layers aged 53 wk were divided into 5 groups with 6 replicates of 16 layers. Birds in the control group were fed a diet supplemented with 60 mg... | ['Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Chickens', 'Diet', 'Dietary Supplements', 'Dose-Response Relationship, Drug', 'Egg Shell', 'Female', 'Methionine', 'Organometallic Compounds', 'Ovum', 'Random Allocation'] | 29,077,932 | [['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G07.203.650.240'], ['G07.203.300.456', 'J02.500.456'], ['G07.690.773.875', 'G07.690.936.500'], ['A13.316'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Changes in proteomic features induced by insulin on vascular smooth muscle cells from spontaneous hypertensive rats in vitro. | Hyperinsulinemia is a risk factor in atherosclerosis formation that it stimulated vascular smooth muscle cells (VSMCs) proliferation and migration. To understand the underlying molecular mechanism involved in the processes of cellular response to insulin, VSMCs from Wistar-Kyoto rat (WKY) and spontaneous hypertensive r... | ['Animals', 'Cell Movement', 'Cell Proliferation', 'Cytoskeleton', 'Gene Expression Profiling', 'Insulin', 'Male', 'Muscle, Smooth, Vascular', 'Phenotype', 'Proteomics', 'Rats', 'Rats, Inbred SHR'] | 20,803,099 | [['B01.050'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.284.430.214.190.750'], ['E05.393.332'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['G05.695'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
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