Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Systemic absorption of gentamicin in the management of active mucosal chronic otitis media. | A prospective study was performed on patients with active mucosal chronic otitis media who were being treated with the gentamicin-containing preparation Gentisone HC. In 27 patients plasma gentamicin levels were measured. Detectable levels were found in 7/27 (26%). Pre- and post-treatment audiometry was performed on 16... | ['Absorption', 'Adult', 'Anti-Bacterial Agents', 'Chronic Disease', 'Female', 'Gentamicins', 'Humans', 'Male', 'Otitis Media', 'Perilymph', 'Prospective Studies'] | 10,542,926 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['M01.060.116'], ['D27.505.954.122.085'], ['C23.550.291.500'], ['D09.408.051.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C09.218.705.663'], ['A12.207.270.517.678'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
REFERENCE UPDATE and REFERENCE MANAGER: personal computer programs for locating and managing references. | REFERENCE UPDATE (a trademark of Research Information Systems, Inc.) is a diskette-based service which provides subscribers with a weekly update on the latest publications in biology and medicine. REFERENCE MANAGER (a registered trademark of Research Information Systems, Inc.) is a microcomputer-based software package ... | ['Bibliographies as Topic', 'Database Management Systems', 'Software'] | 2,698,652 | [['L01.178.682.099', 'L01.453.183'], ['L01.224.068', 'L01.224.900.280', 'N04.452.515.110'], ['L01.224.900']] | ['Information Science [L]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Long-term survival of a patient with multiple abdominal metastasis from endometrial carcinoma treated with multi-portal conformal re-irradiation and chemotherapy. | A patient with recurrent endometrial cancer with multiple abdominal and pelvic tumoral masses was treated with re-irradiation combined with liposomal doxorubicin and oxaliplatin. A multiple field conformal technique was used to deliver a highly accelerated and hypofractionated scheme (15 fractions of 3.5 Gy, within 19 ... | ['Abdominal Neoplasms', 'Combined Modality Therapy', 'Endometrial Neoplasms', 'Female', 'Humans', 'Middle Aged', 'Radiotherapy, Conformal', 'Survival Analysis', 'Time Factors', 'Tomography, X-Ray Computed'] | 21,460,607 | [['C04.588.033'], ['E02.186'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.815.635.700', 'L01.313.500.750.100.710.600.550'], ['E05.318.740.998', 'N05.715.360.750.795', 'N06.850.520.830.998'], ['G01.910.857... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Histocompatibility antigens in multiple sclerosis in children]. | A phenotyping was done in respect of HLA system in 14 children with documented multiple sclerosis (MS), 20 children with potential MS, and 42 their near relations. HLA-B12 antigen was recordable with high frequency (RR = 6.29; P < 0.025) while HLA-B18 with low one (P < 0.01) as compared to normal subjects both among pa... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Female', 'Genetic Predisposition to Disease', 'HLA Antigens', 'Histocompatibility Antigens Class I', 'Humans', 'Male', 'Multiple Sclerosis', 'Phenotype', 'Risk'] | 9,844,877 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['C23.550.291.687.500', 'G05.380.355'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['D12.776.395.550.489', 'D12.776.543.550.439', 'D23.050.301.500.100', 'D23.050.705.552.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.114.375.50... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hematologic and bone marrow changes in children with protein-energy malnutrition. | BACKGROUND: All systems in an organism are affected by protein-energy malnutrition (PEM), but one of the worst affected is the hematopoietic system. Today PEM remains a very serious problem in developing countries. We examined the relationships between clinical features, hematological, and bone marrow changes with seve... | ['Anemia', 'Blood Proteins', 'Bone Marrow', 'Child Nutrition Disorders', 'Child, Preschool', 'Female', 'Folic Acid', 'Humans', 'Infant', 'Infant Nutrition Disorders', 'Iron', 'Male', 'Protein Deficiency', 'Turkey', 'Vitamin B 12'] | 23,987,917 | [['C15.378.071'], ['D12.776.124'], ['A15.382.216'], ['C18.654.180'], ['M01.060.406.448'], ['D03.633.100.733.631.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C18.654.422'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['C18.654.521.500.708'], ['Z01.252.245.500.850'], ['D03.383... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
[Geographic patterns and ecological factors correlates of snake species richness in China]. | Understanding large-scale geographic patterns of species richness as well its underlying mechanisms are among the most significant objectives of macroecology and biogeography. The ecological hypothesis is one of the most accepted explanations of this mechanism. Here, we studied the geographic patterns of snakes and inv... | ['Animals', 'Biodiversity', 'China', 'Ecosystem', 'Environment', 'Population Dynamics', 'Rain', 'Snakes', 'Temperature'] | 22,855,440 | [['B01.050'], ['G16.500.275.157.049', 'N06.230.124.049'], ['Z01.252.474.164'], ['G16.500.275.157', 'N06.230.124'], ['G16.500.275', 'N06.230'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['G16.500.175.859', 'G16.500.275.063.725.395', 'G16.500.750.775.450', 'N06.230.300.100.725.450', 'N06.230.520'], ['B01.050... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Ursolic acid derivative ameliorates streptozotocin-induced diabestic bone deleterious effects in mice. | OBJECTIVE: This study was performed to investigate bone deteriorations of diabetic mice in response to the treatment of ursolic acid derivative (UAD).METHODS: The biomarkers in serum and urine were measured, tibias were taken for the measurement on gene and protein expression and histomorphology analysis, and femurs we... | ['Animals', 'Bone Density', 'Calcium', 'Diabetes Mellitus, Experimental', 'Femur', 'Insulin', 'Insulin-Like Growth Factor I', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Osteoprotegerin', 'RANK Ligand', 'Tibia', 'Triterpenes'] | 26,097,549 | [['B01.050'], ['G11.427.100'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['A02.835.232.043.150'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Atypical intradermal smooth-muscle neoplasm]. | BACKGROUND: We report herein a case of atypical intradermal smooth-muscle neoplasm.PATIENT AND METHODS: A 58-year-old man presented with a painless pinkish-white chest nodule ongoing for two years. Histopathology revealed a proliferation of intradermal smooth-muscle cells. Some atypia and 5 mitoses were seen in the mos... | ['Biopsy', 'Diagnosis, Differential', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Skin Neoplasms', 'Smooth Muscle Tumor', 'Thorax', 'Treatment Outcome'] | 28,242,098 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789'], ['C04.588.805', 'C17.800.882'], ['C04.557.450.590.800'], ['A01.923.761'], ['E01.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
17â-Estradiol enhances sulforaphane cardioprotection against oxidative stress. | The lower incidence of ischemic heart disease in female with respect to male gender suggests the possibility that female sex hormones could have specific effects in cardiovascular protection. 17â-Estradiol is the predominant premenopausal circulating form of estrogen and has a protective role on the cardiovascular syst... | ['Animals', 'Antioxidants', 'Cardiotonic Agents', 'Drug Synergism', 'Enzymes', 'Estradiol', 'Estrogen Receptor alpha', 'Estrogen Receptor beta', 'Hydrogen Peroxide', 'Isothiocyanates', 'Microscopy, Electron, Transmission', 'Myocytes, Cardiac', 'Oxidative Stress', 'Proto-Oncogene Proteins c-akt', 'Rats, Sprague-Dawley',... | 28,110,122 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D27.505.954.411.222', 'D27.720.799.080'], ['G07.690.773.968.477'], ['D08.811'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D12.776.826.750.350.174'], ['D12.776.826.750.350.262'], ['D01.248.497.158.685.750.424', 'D01.339.431.37... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
It's only in your head: expectancy of aversive auditory stimulation modulates stimulus-induced auditory cortical alpha desynchronization. | Increasing evidence underlines the functional importance of non-phase-locked cortical oscillatory rhythms. Among the different oscillations, alpha (8-12 Hz) has been shown to be modulated by anticipation or attention, suggesting a top-down influence. However, most studies to date have been conducted in the visual modal... | ['Acoustic Stimulation', 'Adult', 'Auditory Cortex', 'Auditory Perception', 'Cortical Synchronization', 'Female', 'Humans', 'Male', 'Young Adult'] | 22,209,810 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.116'], ['A08.186.211.200.885.287.500.814.249', 'A08.186.211.200.885.287.500.863.297'], ['F02.463.593.071', 'G07.888.125'], ['E01.370.376.300.437.500', 'E01.370.405.245.575.500', 'G07.265.256.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress. | Exposure of yeast to increases in extracellular osmolarity activates the Hog1 mitogen-activated protein kinase (MAPK), which is essential for the induction of gene expression required for cell survival upon osmotic stress. Several genes are regulated in response to osmotic stress by Sko1, a transcriptional repressor of... | ['Amino Acid Sequence', 'Basic-Leucine Zipper Transcription Factors', 'Cyclic AMP-Dependent Protein Kinases', 'DNA-Binding Proteins', 'Fungal Proteins', 'Gene Expression Regulation, Fungal', 'Genes, Reporter', 'Immunoblotting', 'Mitogen-Activated Protein Kinases', 'Molecular Sequence Data', 'Mutation', 'Nuclear Protein... | 11,230,135 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.260.108', 'D12.776.930.127'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['D12.776.260'], ['D12.776.354'], ['G05.308.330'], ['G05.360.340.024.340.435'], ['E05.478.566.320', 'E05.601.470.320'], ['D08.811.913.696.620.682.70... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The effect of non-antihypertensive doses of angiotensin converting enzyme inhibitor on myocardial necrosis and hypertrophy in young rats with renovascular hypertension. | In renovascular hypertensive rats, low doses of angiotensin converting enzyme (ACE) inhibitors have been found to prevent myocardial hypertrophy independent of blood pressure level. This finding would suggest humoral rather than mechanical control of myocyte growth. The aim of this study was to examine the effect of no... | ['Angiotensin-Converting Enzyme Inhibitors', 'Animals', 'Blood Pressure', 'Cardiomegaly', 'Dose-Response Relationship, Drug', 'Hypertension, Renovascular', 'Hypertrophy, Left Ventricular', 'Male', 'Necrosis', 'Organ Size', 'Ramipril', 'Rats', 'Rats, Wistar'] | 10,469,264 | [['D27.505.519.389.745.085'], ['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C14.280.195', 'C23.300.775.250'], ['G07.690.773.875', 'G07.690.936.500'], ['C12.777.419.331.490', 'C13.351.968.419.331.490', 'C14.907.489.631.485'], ['C14.280.195.400', 'C23.300.775.250.400'], ['C23.550.717'], ['E01.370.600.115.100... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The control of ichthyophthiriasis by a medicated food containing quinine: efficacy tests and ultrastructure investigations. | The present report demonstrates that a medicated food containing quinine kills the skin-inhabiting trophozoite stage of Ichthyophthirius multifiliis in ornamental fish. Artificially infected swordtails. (Xiphophorus helleri), black mollies (Poecilia sphenops), and black neons (Hyphessobrycon herbertaxelrodi) were used ... | ['Administration, Oral', 'Animals', 'Antiprotozoal Agents', 'Ciliophora Infections', 'Fish Diseases', 'Fishes', 'Hymenostomatida', 'Microscopy, Electron', 'Quinine'] | 8,897,504 | [['E02.319.267.100'], ['B01.050'], ['D27.505.954.122.250.100'], ['C01.610.752.200'], ['C22.362'], ['B01.050.150.900.493'], ['B01.043.185.650.375'], ['E01.370.350.515.402', 'E05.595.402'], ['D03.132.206.719', 'D03.605.687.762', 'D03.633.100.810.762']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A web-based normative data tool for assessing cognitive performance in healthy older Australians. | A decline in cognition greater than expected with ageing and accompanied by subjective cognitive concerns or functional changes may be indicative of a dementing disorder. The capacity to correctly identify cognitive decline relies on comparisons with normative data from a suitably matched healthy reference group with r... | ['Aged', 'Aged, 80 and over', 'Australia', 'Cognition Disorders', 'Databases, Factual', 'Female', 'Humans', 'Internet', 'Male', 'Middle Aged', 'Neuropsychological Tests'] | 21,401,481 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.639.100', 'Z01.678.100.373'], ['F03.615.250'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['M01.060.116.630'], ['F04.711.513']] | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Cefoperazone-sulbactam for treatment of intra-abdominal infections: results from a randomized, parallel group study in India. | BACKGROUND: Combinations of a third-generation cephalosporin and metronidazole, with or without an aminoglycoside, often are used for the treatment of intra-abdominal infections in surgical settings. Simpler regimens that preserve an adequate spectrum of coverage, but allow easier administration and have fewer side eff... | ['Abdominal Abscess', 'Adolescent', 'Adult', 'Aged', 'Amikacin', 'Anti-Bacterial Agents', 'Cefoperazone', 'Ceftazidime', 'Child', 'Drug Therapy, Combination', 'Female', 'Gram-Negative Bacteria', 'Gram-Negative Bacterial Infections', 'Humans', 'India', 'Male', 'Metronidazole', 'Middle Aged', 'Peritonitis', 'Sulbactam', ... | 18,570,578 | [['C01.830.025.020'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D09.408.051.476.060'], ['D27.505.954.122.085'], ['D02.065.589.099.249.150.160', 'D02.886.665.074.150.160', 'D03.633.100.300.249.150.160'], ['D02.065.589.099.249.210.150', 'D02.886.665.074.210.150', 'D03.633.100.300.249.210.150'], ['M01.060.4... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mutations in the TAR hairpin affect the equilibrium between alternative conformations of the HIV-1 leader RNA. | The HIV-1 untranslated leader RNA can adopt two mutually exclusive conformations that represent alternative secondary structures. This leader RNA can fold either an extended duplex through long-distance base pairing or a branched conformation in which the RNA locally folds into hairpin structures. Both leader RNA confo... | ['Base Pairing', 'Base Sequence', 'Dimerization', 'HIV Long Terminal Repeat', 'HIV-1', 'Magnesium', 'Molecular Sequence Data', 'Mutation', 'Nucleic Acid Conformation', 'Nucleic Acid Denaturation', 'RNA Stability', 'RNA, Messenger', 'RNA, Viral', 'Sodium', 'Temperature', 'Thermodynamics'] | 11,410,668 | [['G02.111.570.820.486.100', 'G02.111.611.500', 'G05.360.580.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.206', 'G03.230'], ['G02.111.570.080.708.850.400', 'G05.360.080.708.850.400'], ['B04.820.650.589.650.350.400'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['L01.453.245.667... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
A model of pulsatile flow in a uniform deformable vessel. | Simulations of blood flow in natural and artificial conduits usually require large computers for numerical solution of the Navier-Stokes equations. Often, physical insight into the fluid dynamics is lost when the solution is purely numerical. An alternative to solving the most general form of the Navier-Stokes equation... | ['Animals', 'Blood Circulation', 'Blood Flow Velocity', 'Blood Pressure', 'Blood Vessels', 'Carotid Arteries', 'Dogs', 'Models, Cardiovascular', 'Movement', 'Regional Blood Flow', 'Rheology', 'Stress, Mechanical'] | 1,733,987 | [['B01.050'], ['G09.330.100'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07.015'], ['A07.015.114.186'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.599.395.161'], ['G07.568', 'G11.427.410'], ['G09.330.100.780'], ['E05.830', 'H01.671.808'], ['G01.374.835']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Longitudinal evaluation of liver stiffness in three pediatric patients with veno-occlusive disease. | Liver stiffness measurement by transient elastography is a non-invasive ultrasound-based technique used mainly for the evaluation of liver fibrosis in patients with chronic liver diseases. Some authors have suggested that it could be useful in the assessment of hepatic complications during hematopoietic stem cell trans... | ['Adolescent', 'Child', 'Elasticity Imaging Techniques', 'Female', 'Hematopoietic Stem Cell Transplantation', 'Hepatic Veno-Occlusive Disease', 'Humans', 'Liver'] | 31,081,161 | [['M01.060.057'], ['M01.060.406'], ['E01.370.350.850.270'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['C06.552.360', 'C14.907.460'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Medullary sponge kidney and urolithiasis. | A review of the urographic findings in 200 patients with renal colic due to urolithiasis demonstrated radiological evidence of medullary sponge kidney in 34, an incidence of 17%. In the majority, the diagnosis was readily made and the changes were bilateral and extensive. This relatively high incidence suggests that me... | ['Colic', 'Female', 'Humans', 'Kidney Calculi', 'Kidney Diseases', 'Male', 'Medullary Sponge Kidney', 'Radiography'] | 7,083,742 | [['C16.614.166'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.600.500', 'C12.777.967.249.500', 'C12.777.967.500.503', 'C13.351.968.419.600.500', 'C13.351.968.967.249.500', 'C13.351.968.967.500.503', 'C23.300.175.850.550'], ['C12.777.419', 'C13.351.968.419'], ['C12.777.419.403.500', 'C13.351.968.419.4... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Plasma beta-amyloid (A beta) 40 concentration, lipid status and age in humans. | The circulation constitutes a potential source of the beta-amyloid (A beta) protein deposited cerebrally in Alzheimer's disease (AD). Cardiovascular risk factors, including hyperlipidaemia, may be involved in the pathogenesis of AD. Plasma A beta 40 was measured by radioimmunoassay in normal and hyperlipidaemic subject... | ['Adult', 'Aged', 'Aging', 'Amyloid beta-Peptides', 'Female', 'Humans', 'Hyperlipidemias', 'Male', 'Middle Aged', 'Peptide Fragments', 'Radioimmunoassay', 'Statistics as Topic'] | 15,308,295 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.584.500.500'], ['M01.060.116.630'], ['D12.644.541'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['E05.318.740', 'H01.548.8... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Orbital infection as a complication of sinusitis: are diagnostic and treatment trends changing? | Orbital infection has long been the most common complication of sinusitis. In light of our increased knowledge of sinusitis, improved diagnostic tools, and new pharmacologic and surgical treatments, we investigated whether trends in diagnosis and treatment are changing. We reviewed the charts of all 43 patients who had... | ['Abscess', 'Adolescent', 'Adult', 'Bacterial Infections', 'Cellulitis', 'Child', 'Child, Preschool', 'Cohort Studies', 'Endoscopy', 'Female', 'Follow-Up Studies', 'Forecasting', 'Humans', 'Infant', 'Male', 'Orbital Diseases', 'Retrospective Studies', 'Risk Assessment', 'Severity of Illness Index', 'Sinusitis', 'Treatm... | 12,472,030 | [['C01.830.025', 'C23.550.470.756.100'], ['M01.060.057'], ['M01.060.116'], ['C01.150.252'], ['C01.800.130', 'C01.830.200', 'C17.300.185', 'C23.550.470.756.200'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.388.250', 'E04.502.250'], ['E05... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The structure of the perivascular compartment in the old canine brain: a case study. | Dilatation of periarteriolar spaces in MRI of the ageing human brains occurs in white matter (WM), basal ganglia and midbrain but not in cerebral cortex. Perivenous collagenous occurs in periventricular but not in subcortical WM.Here we test the hypotheses that (a) the capacity for dilatation of periarteriolar spaces c... | ['Aging', 'Animals', 'Arterioles', 'Brain', 'Dogs', 'White Matter'] | 28,982,724 | [['G07.345.124'], ['B01.050'], ['A07.015.114.060', 'A07.015.461.080'], ['A08.186.211'], ['B01.050.150.900.649.313.750.250.216.200'], ['A08.186.211.204', 'A08.186.854.880']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Laboratory tests for identification or exclusion of heparin induced thrombocytopenia: HIT or miss? | Heparin induced thrombocytopenia (HIT) is a potentially fatal condition that arises subsequent to formation of antibodies against complexes containing heparin, usually platelet-factor 4-heparin ("anti-PF4-heparin"). Assessment for HIT involves both clinical evaluation and, if indicated, laboratory testing for confirmat... | ['Antibodies', 'Clinical Laboratory Techniques', 'Diagnostic Errors', 'Heparin', 'Humans', 'Platelet Activation', 'Sensitivity and Specificity', 'Thrombocytopenia'] | 29,164,662 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E01.370.225', 'E05.200'], ['E01.354', 'N02.421.450.280'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.188.390.600'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Production of small nano-sized particles by complex formation between polycations and linearized plasmid DNA at a low pH. | We report on the technical advance of linearized pDNA (pDNA(linear)) above the circular one (pDNA(circ)) for preparation of small-sized DNA/polycation complexes (DPC) at a low pH. Also, the resistance of the DPC formed with pDNA(linear) against poly-L-asparagine indicates that effective ion-pairing occurred between the... | ['DNA', 'DNA, Circular', 'Hydrogen-Ion Concentration', 'Nanostructures', 'Peptides', 'Plasmids', 'Polyamines', 'Polyelectrolytes'] | 23,684,164 | [['D13.444.308'], ['D13.444.308.283', 'G02.111.570.820.486.212', 'G05.360.580.156'], ['G02.300'], ['J01.637.512'], ['D12.644'], ['G05.360.600'], ['D02.092.782'], ['D01.248.700', 'D05.750.230']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
LINGO-1 antagonist promotes functional recovery and axonal sprouting after spinal cord injury. | LINGO-1 is a CNS-specific protein and a functional component of the NgR1/p75/LINGO-1 and NgR1/TAJ(TROY)/LINGO-1 signaling complexes that mediate inhibition of axonal outgrowth. These receptor complexes mediate the axonal growth inhibitory effects of Nogo, myelin-associated glycoprotein (MAG) and oligodendrocyte-myelin ... | ['Analysis of Variance', 'Animals', 'Apoptosis', 'Axons', 'Caspase 3', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Forelimb', 'Humans', 'Immunohistochemistry', 'In Situ Nick-End Labeling', 'MAP Kinase Kinase 4', 'Membrane Proteins', 'Nerve Regeneration', 'Nerve Tissue Proteins', 'Organogenesis', 'Pro... | 17,011,208 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G04.146.954.035'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Frequency, timing, and course of depressive symptomatology after whiplash. | STUDY DESIGN: Population-based incidence cohort.OBJECTIVE: To report the incidence, timing, and course of depressive symptoms after whiplash.SUMMARY OF BACKGROUND DATA: Evidence is conflicting about the frequency, time of onset, and course of depressive symptoms after whiplash.METHODS: Adults making an insurance claim ... | ['Accidents, Traffic', 'Adult', 'Canada', 'Chronic Disease', 'Cohort Studies', 'Depression', 'Female', 'Humans', 'Insurance, Accident', 'Male', 'Mental Disorders', 'Middle Aged', 'Recurrence', 'Surveys and Questionnaires', 'Time Factors', 'Whiplash Injuries'] | 16,845,342 | [['N06.850.135.392'], ['M01.060.116'], ['Z01.107.567.176'], ['C23.550.291.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.409'], ['F03'], ['M01.060.116.630'], ['C23.550.291.937'], ['E05.318.... | ['Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Exploring the experiences of nurses studying professional doctorates. | Recently there has been a rapid increase in the number of professional doctorates being undertaken in the UK. Nursing doctorates in particular are relatively new to the UK and therefore little is known about nurses' experiences of them, especially from a qualitative perspective. The aim of this study was to explore the... | ['Adaptation, Psychological', 'Data Collection', 'Education, Nursing, Graduate', 'Humans', 'Leadership', "Nurse's Role", 'Nursing Education Research', 'Nursing Methodology Research', 'Students, Nursing', 'United Kingdom'] | 23,905,230 | [['F01.058'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['I02.358.337.450', 'I02.358.462.565'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.609'], ['F01.829.316.616.625.450', 'N05.300.100.337'], ['H01.770.644.145.390.413', 'H02.478.395.413', 'I02.358.462.612', 'N04.590.233.508... | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
â-catenin directly sequesters adipocytic and insulin sensitizing activities but not osteoblastic activity of PPARã2 in marrow mesenchymal stem cells. | Lineage allocation of the marrow mesenchymal stem cells (MSCs) to osteoblasts and adipocytes is dependent on both Wnt signaling and PPARã2 activity. Activation of PPARã2, an essential regulator of energy metabolism and insulin sensitivity, stimulates adipocyte and suppresses osteoblast differentiation and bone formatio... | ['Adipocytes', 'Anilides', 'Animals', 'Bone Marrow Cells', 'Cell Differentiation', 'Cell Line', 'Gene Expression Regulation', 'Gene Silencing', 'Insulin', 'Lithium Chloride', 'Mesenchymal Stem Cells', 'Mice', 'Mutation', 'Osteoblasts', 'PPAR gamma', 'Protein Stability', 'Proteolysis', 'RNA Interference', 'Rosiglitazone... | 23,272,157 | [['A11.329.114'], ['D02.065.199', 'D02.092.146.113'], ['B01.050'], ['A11.148', 'A15.378.316'], ['G04.152'], ['A11.251.210'], ['G05.308'], ['G05.308.203.374'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D01.210.450.150.450', 'D01.510.500'], ['A11.329.830.500', 'A11.872.590.500'], ['B01.050.150.900... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Status of SARS-CoV-2 in cerebrospinal fluid of patients with COVID-19 and stroke. | BACKGROUND: Emergence of the novel corona virus (severe acute respiratory syndrome (SARS)-CoV-2) in December 2019 has led to the COVID-19 pandemic. The extent of COVID-19 involvement in the central nervous system is not well established, and the presence or the absence of SARS-CoV-2 particles in the cerebrospinal fluid... | ['Adult', 'Betacoronavirus', 'COVID-19', 'Coronavirus Infections', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pandemics', 'Pneumonia, Viral', 'SARS-CoV-2', 'Stroke'] | 32,354,770 | [['M01.060.116'], ['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['C01.925.782.600.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N06.850.290.200.6... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Assessing fitness to detain in police custody. | This article outlines the role of the custody nurse in assessing an individual's fitness to be detained. It addresses all aspects of the assessment, including consent, responsibilities and the structure of the clinical examination. It explores ways to ensure that the detainee's rights and welfare are maintained and the... | ['Humans', 'Nursing Staff', 'Police', 'Prisoners', 'Risk Assessment', 'United Kingdom'] | 26,554,997 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.680', 'N02.360.680'], ['M01.526.373.750', 'M01.526.760'], ['M01.729'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['Z01.542.363']] | ['Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The first community-based sexually transmitted disease/HIV intervention trial for female sex workers in China. | OBJECTIVES: This study was the first community-based intervention to test feasibility and effectiveness of an intervention targeting sex workers in China.DESIGN: Prospective, community-based, pre/post-intervention trial.METHOD: Thirty establishments in Chengjiang, 34 in Ruili and 23 in Longchuan were selected for the s... | ['Adolescent', 'Adult', 'Audiovisual Aids', 'Cartoons as Topic', 'China', 'Condoms', 'Feasibility Studies', 'Female', 'HIV Infections', 'Health Education', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Middle Aged', 'Pamphlets', 'Program Evaluation', 'Risk-Taking', 'Sex Work', 'Sexually Transmitted Diseases', 'So... | 18,172,397 | [['M01.060.057'], ['M01.060.116'], ['J01.897.280.500', 'L01.178.820.090'], ['K01.093.206.332'], ['Z01.252.474.164'], ['E07.190.270.150'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.81... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Humanities [K]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and P... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Changes in the number of active sweat glands (palmar sweat index, PSI) during a distressing film. | Changes of the number of active palmar sweat glands (palmar sweat index, PSI) as assessed by the plastic finger-print method were studied in two groups of female students (n = 21 each). In both samples experiments involved an initial adaptation period, several relaxation phases and an activation period (presentation of... | ['Adult', 'Arousal', 'Fear', 'Female', 'Galvanic Skin Response', 'Heart Rate', 'Humans', 'Motion Pictures', 'Sweat Glands', 'Sweating'] | 8,003,589 | [['M01.060.116'], ['F02.830.104', 'G11.561.035'], ['F01.470.361'], ['E05.796.332', 'F02.830.702.315', 'F04.669.332', 'G07.265.563', 'G13.750.415'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.897.280.500.598', 'K01.093.545', 'L01.178.590.500', 'L01.178.820.090.598'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Humanities [K]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 |
Artificial Organelles: Reactions inside Protein-Polymer Supramolecular Assemblies. | Reactions inside confined compartments at the nanoscale represent an essential step in the development of complex multifunctional systems to serve as molecular factories. In this respect, the biomimetic approach of combining biomolecules (proteins, enzymes, mimics) with synthetic membranes is an elegant way to create f... | ['Nanotechnology', 'Organelles', 'Permeability', 'Polymers', 'Proteins'] | 27,363,371 | [['H01.603', 'J01.897.520.600'], ['A11.284.430.214.190.875'], ['G02.723'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['D12.776']] | ['Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Circadian Activity Rhythms and Sleep in Nurses Working Fixed 8-hr Shifts. | Shift work is associated with adverse health outcomes. The aim of this study was to explore the effects of shift work on circadian activity rhythms (CARs) and objective and subjective sleep quality in nurses. Female day-shift (n = 16), evening-shift (n = 6), and night-shift (n = 13) nurses wore a wrist actigraph to mon... | ['Actigraphy', 'Adult', 'Circadian Rhythm', 'Female', 'Humans', 'Nurses', 'Sleep', 'Work Schedule Tolerance'] | 25,332,463 | [['E01.370.520.049', 'E05.003.500'], ['M01.060.116'], ['G07.180.562.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.650', 'N02.360.650'], ['F02.830.855', 'G11.561.803'], ['I03.946.225.375', 'N04.452.677.650.375']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Non-steroidal anti-inflammatory drugs, Cyclooxygenase-2 inhibitors and paracetamol use in Queensland and in the whole of Australia. | BACKGROUND: Cross national drug utilization studies can provide information about different influences on physician prescribing. This is important for medicines with issues around safety and quality of use, like non selective non-steroidal anti-inflammatory drugs (ns-NSAIDs) and cyclo-oxygenase-2 (COX-2) inhibitors. To... | ['Acetaminophen', 'Adolescent', 'Adult', 'Aged', 'Anti-Inflammatory Agents, Non-Steroidal', 'Australia', 'Cyclooxygenase 2 Inhibitors', 'Drug Utilization', 'Female', 'Humans', 'Male', 'Middle Aged', 'Musculoskeletal Diseases', "Practice Patterns, Physicians'", 'Queensland'] | 18,816,393 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['Z01.639.100', 'Z01.678.100.373'], ['D27.505.519.389.310.500', 'D27.505.696.663.850.014.040.500.500.500', 'D27.505.954.158.030.5... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase. | Autophagy is essential for cellular survival and energy homeostasis under nutrient deprivation. Despite the emerging importance of nuclear events in autophagy regulation, epigenetic control of autophagy gene transcription remains unclear. Here, we report fasting-induced Fibroblast Growth Factor-21 (FGF21) signaling act... | ['Animals', 'Autophagy', 'Epigenesis, Genetic', 'Fasting', 'Fatty Liver', 'Fibroblast Growth Factors', 'Hepatocytes', 'Humans', 'Jumonji Domain-Containing Histone Demethylases', 'Lipolysis', 'Liver', 'Male', 'Membrane Proteins', 'Mice', 'Mice, Knockout', 'Mice, Obese', 'PPAR alpha', 'Phosphorylation', 'Protein Binding'... | 32,042,044 | [['B01.050'], ['G04.011'], ['G05.308.203'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['C06.552.241'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['A11.436.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.682.662.582.475.500', 'D08.811.682.690.416.388'], ['G02.111.5... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The cost of immunosuppressive therapies currently used in patients with thyroid eye disease. | Thyroid eye disease (TED) is an inflammatory condition of the orbit occurring in patients with autoimmune disease. In patients with mild TED, the most important therapeutic measure is reassurance. In severe cases, immunosuppressive therapy is the mainstay of treatment and around 10 immunosuppressive regimens have been ... | ['Drug Costs', 'Europe', 'Graves Disease', 'Humans', 'Immunosuppressive Agents', 'Treatment Outcome'] | 15,762,038 | [['N03.219.151.400.350', 'N05.300.375.300'], ['Z01.542'], ['C11.675.349.500', 'C19.874.283.605', 'C19.874.397.370', 'C20.111.555'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Phase-contrast MRI volume flow--a comparison of breath held and navigator based acquisitions. | BACKGROUND: Magnetic Resonance Imaging (MRI) 2D phase-contrast flow measurement has been regarded as the gold standard in blood flow measurements and can be performed with free breathing or breath held techniques. We hypothesized that the accuracy of flow measurements obtained with segmented phase-contrast during breat... | ['Aged', 'Aged, 80 and over', 'Cardiac-Gated Imaging Techniques', 'Contrast Media', 'Coronary Disease', 'Echocardiography', 'Electrocardiography', 'Female', 'Humans', 'Magnetic Resonance Imaging, Cine', 'Male', 'Middle Aged', 'Respiratory-Gated Imaging Techniques'] | 27,021,353 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350.130.500'], ['D27.505.259.500', 'D27.720.259'], ['C14.280.647.250', 'C14.907.585.250'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.37... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dorsal laminectomy in the adult mouse: a model for nervous system research. | Animal strains with specific genetic mutations can serve as powerful tools to study normal and pathologic cellular and molecular processes. The mammalian species with the largest number of known genetic mutations is the mouse. In spinal cord research, mice have not been used as extensively as other species because of t... | ['Animals', 'Disease Models, Animal', 'Laminectomy', 'Male', 'Mice', 'Mice, SCID', 'Spinal Cord', 'Spinal Cord Injuries'] | 8,699,828 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.718.563', 'E04.188.400', 'E04.525.450', 'E04.555.350'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.780'], ['A08.186.854'], ['C10.228.854.763', 'C10.900.850', 'C26.819']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses. | Interleukin 17 (IL-17)-producing T helper 17 cells (T(H)-17 cells) have been described as a T helper cell subset distinct from T helper type 1 (T(H)1) and T(H)2 cells, with specific functions in antimicrobial defense and autoimmunity. The factors driving human T(H)-17 differentiation remain controversial. Using a syste... | ['Cell Differentiation', 'Cytokines', 'Humans', 'Interleukin-17', 'Interleukin-23', 'T-Lymphocytes, Helper-Inducer', 'Transforming Growth Factor beta'] | 18,454,150 | [['G04.152'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.517', 'D12.776.467.374.465.517', 'D23.529.374.465.517'], ['D12.644.276.374.465.759', 'D12.776.467.374.465.759', 'D23.529.374.465.550'], ['A11.118.637.555.567.550.500.400', 'A11.118... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The descending branch of the lateral circumflex femoral artery as an alternative conduit for coronary artery bypass grafting: Experience from an anatomical, radiological and histological study. | The descending branch of the lateral circumflex femoral artery (DBLCFA) has been suggested as an option for use in coronary artery bypass grafting (CABG). Our aim was to combine radiological examination, surgical and anatomical preparation, and histological assessment of the DBLCFA to map its variability and to assess ... | ['Aged', 'Computed Tomography Angiography', 'Coronary Artery Bypass', 'Female', 'Femoral Artery', 'Humans', 'Male', 'Middle Aged', 'Reference Values'] | 27,213,916 | [['M01.060.116.100'], ['E01.370.350.350.810.335', 'E01.370.350.567.250', 'E01.370.350.600.350.700.810.335', 'E01.370.350.700.700.810.335', 'E01.370.350.700.810.810.568', 'E01.370.350.825.810.810.499'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['A07.015.114.351'], ['B01.050.150.900.649.313.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Human umbilical cord-derived mesenchymal stem cells downregulate inflammatory responses by shifting the Treg/Th17 profile in experimental colitis. | BACKGROUND/AIMS: The aim of this study was to evaluate the effect and mechanisms of human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) on immune responses in murine colitis.METHODS: Mice with dextran sulfate sodium (DSS)-induced colitis were injected intraperitoneally with hUC-MSCs or human bone marrow-deri... | ['Animals', 'Cell Proliferation', 'Colitis', 'Cytokines', 'Dextran Sulfate', 'Disease Models, Animal', 'Down-Regulation', 'Female', 'Flow Cytometry', 'Humans', 'Inflammation', 'Lymph Nodes', 'Mesenchymal Stem Cell Transplantation', 'Mesenchymal Stem Cells', 'Mice', 'Mice, Inbred C57BL', 'Mucous Membrane', 'Spleen', 'T-... | 24,280,970 | [['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['C06.405.205.265', 'C06.405.469.158.188'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D09.698.365.272.300'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['E01.370.225.500.363.342', 'E01.370.225.500... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Follow-up and counselling after pelvic inflammatory disease: CNGOF and SPILF Pelvic Inflammatory Diseases Guidelines]. | OBJECTIVES: To determine the procedures for follow-up and counselling of patients after pelvic inflammatory disease (PID).METHODS: A search in the Cochrane database, PubMed, and Google was performed using keywords related to follow-up and PID to identify reports published between 1990 and 2018. All studies published in... | ['Chlamydia trachomatis', 'Condoms', 'Contraception', 'Counseling', 'Female', 'Follow-Up Studies', 'Humans', 'Infertility, Female', 'Mycoplasma genitalium', 'Neisseria gonorrhoeae', 'Pelvic Inflammatory Disease', 'Pelvic Pain', 'Recurrence', 'Risk Factors', 'Sexually Transmitted Diseases', 'Vagina'] | 30,878,686 | [['B03.440.190.190.190.750'], ['E07.190.270.150'], ['E02.875.194'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['B03.440.860.580... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Play therapy and children with disabilities. | Play therapy allows children with developmental and health disabilities to discover what physical and emotional strengths they have in relation to their disabilities. Play therapy may be directive or nondirective, emotionally or physically focused. Suggestions for specific activities are presented for providing play th... | ['Child', 'Disabled Persons', 'Humans', 'Internal-External Control', 'Play Therapy', 'Play and Playthings', 'Self Concept'] | 8,119,836 | [['M01.060.406'], ['M01.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['E02.190.888.625', 'F04.754.664'], ['I03.450.642.693'], ['F01.752.747.792']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Safe abortions in an illegal context: perceptions from service providers in Belgium. | Until April 1990 abortion was illegal in Belgium all circumstances. However, a small group of health professionals had long provided high-quality abortion services in outpatient facilities and in hospitals. This study is a qualitative analysis of perceptions among providers of safe abortion in Belgium before and after ... | ['Abortion Applicants', 'Abortion, Criminal', 'Abortion, Induced', 'Adolescent', 'Adult', 'Attitude of Health Personnel', 'Belgium', 'Contraception Behavior', 'Cross-Cultural Comparison', 'Female', 'Gestational Age', 'Humans', 'Male', 'Patient Care Team', 'Pregnancy', 'Pregnancy in Adolescence', 'Religion and Medicine'... | 8,351,696 | [['M01.050'], ['I01.198.240.089'], ['E04.520.050'], ['M01.060.057'], ['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['Z01.542.115'], ['F01.145.688.500', 'G08.686.784.891.500'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Effects of repeated social stress on leukocyte distribution in bone marrow, peripheral blood and spleen. | Leukocyte trafficking between the various body compartments has an important surveillance function that ensures the detection of antigen and enables the immune system to initiate a rapid and effective response. Repeated social defeat of group-housed male mice induced by daily, acute encounters with an aggressive conspe... | ['Analysis of Variance', 'Animals', 'Behavior, Animal', 'Bone Marrow', 'Erythrocytes', 'Flow Cytometry', 'Leukocytes', 'Lymphocytes', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Monocytes', 'Social Behavior', 'Spleen', 'Stress, Psychological', 'Time Factors'] | 14,975,591 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['F01.145.113'], ['A15.382.216'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Rofecoxib, a COX-2 inhibitor, does not inhibit human gastric mucosal prostaglandin production. | BACKGROUND & AIMS: Rofecoxib, an inhibitor of the inducible cyclooxygenase (COX)-2 enzyme, appears not to cause acute gastroduodenal injury or chronic ulceration. To attribute this to COX-2 selectivity with sparing of gastric mucosal prostaglandin synthesis requires direct proof.METHODS: Twenty-four healthy, nonsmoking... | ['Adult', 'Cross-Over Studies', 'Cyclooxygenase 1', 'Cyclooxygenase 2', 'Cyclooxygenase 2 Inhibitors', 'Cyclooxygenase Inhibitors', 'Double-Blind Method', 'Female', 'Gastric Mucosa', 'Humans', 'Isoenzymes', 'Lactones', 'Lipopolysaccharides', 'Male', 'Membrane Proteins', 'Naproxen', 'Prostaglandin-Endoperoxide Synthases... | 11,231,941 | [['M01.060.116'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D08.811.600.720.500'], ['D08.811.600.720.750'], ['D27.505.519.389.310.500', 'D27.505.696.663.850.014.040.500.500.500', 'D27.505.954.158.030.500.500', 'D27.505.954.329.030.500.500'], ['D27.505.519.389.310', 'D27.505.696.663.850.014.04... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Memory disorders and deep structures of the brain]. | Clinical and neuropsychologic examination of 141 patients with arteriovenous malformations (AVM) was examined according to A.R.Lurye method. AVM of caudate nucleus were found in 27 patients, of thalamus in 34 ones, of hippocampal formation in 39 individuals, of gyrus cinguli in 41 cases. 102 patients were operated. Bot... | ['Adolescent', 'Adult', 'Caudate Nucleus', 'Child', 'Female', 'Gyrus Cinguli', 'Hippocampus', 'Humans', 'Intracranial Arteriovenous Malformations', 'Male', 'Memory Disorders', 'Middle Aged', 'Neuropsychological Tests', 'Thalamus'] | 10,533,246 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211.200.885.287.249.487.550.184'], ['M01.060.406'], ['A08.186.211.180.590.500', 'A08.186.211.200.885.287.500.382.500'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.520', 'C10.500.190.500', 'C1... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Family practitioners' intervention against smoking in Germany and the UK: does remuneration affect preventive activity? | The effect of different systems of remuneration on preventive activity of family practitioners (FPs) were studied. Interventions against smoking were compared in FPs' practices in Germany and the UK. Almost 800 consecutively attending patients were included in a cross-sectional survey. Smoking prevalence was remarkably... | ['Cross-Sectional Studies', 'Family Practice', 'Germany', 'Humans', 'Logistic Models', 'Odds Ratio', 'Prevalence', 'Smoking', 'Smoking Cessation', 'Smoking Prevention', 'United Kingdom'] | 8,806,158 | [['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['H02.403.340.500'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450', 'N... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
The secondary sex ratio, paternal age, maternal age and birth order in Japan. | The simultaneous effects of several variables on the secondary sex ratio have been examined using data from over 3.7 million births which occurred in Japan during 1975--6. A weak and negative association between sex ratio and birth order was observed but it was not significant in the statistical sense. A negative effec... | ['Adolescent', 'Adult', 'Birth Order', 'Female', 'Humans', 'Japan', 'Male', 'Maternal Age', 'Middle Aged', 'Models, Biological', 'Paternal Age', 'Regression Analysis', 'Sex Ratio'] | 475,333 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exit from mitosis induced by a calcium transient: the relation to the MPF and InsP3 dynamics. | Cells divide only after passing through a control point in late G1. This passage is followed by the accumulation of the mitotic cyclin which binds to p34cdc2, allowing for the subsequent phosphorylation and dephosphorylation of the latter protein. It is the active MPF, i.e. the phosphorylated mitotic cyclin-p34cdc2 kin... | ['Animals', 'CDC2 Protein Kinase', 'Calcium', 'Cyclins', 'Cytosol', 'Inositol 1,4,5-Trisphosphate', 'Kinetics', 'Mathematics', 'Mitosis', 'Models, Biological', 'Phosphorylation'] | 7,888,611 | [['B01.050'], ['D08.811.913.696.620.682.700.646.500.500.250', 'D08.811.913.696.620.682.700.646.500.984.500', 'D12.644.360.250.067.249', 'D12.644.360.250.580.500', 'D12.776.167.200.067.249', 'D12.776.167.200.580.500', 'D12.776.476.250.067.249', 'D12.776.476.250.580.500', 'D12.776.744.360'], ['D01.268.552.100', 'D01.552.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Myoepithelial sialadenitis versus low-grade non-Hodgkin's lymphoma of the salivary gland in FNAB: is discrimination by means of an image processing system possible? | The diagnosis of myoepithelial sialadenitis (MESA) in fine needle aspiration biopsy may be difficult. There is a dense lymphocytic infiltration in the gland and discrimination between a hyperimmune reaction and a low grade non-Hodgkin's lymphoma (NHL) of B-cell origin may be impossible. To get additional diagnostically... | ['Biopsy, Needle', 'Decision Trees', 'Diagnosis, Computer-Assisted', 'Diagnosis, Differential', 'Humans', 'Image Processing, Computer-Assisted', 'Lymphoma, Non-Hodgkin', 'Myoepithelioma', 'Salivary Gland Neoplasms', 'Sialadenitis'] | 10,757,047 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['G17.162.500'], ['E01.158', 'L01.313.500.750.100.158'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
What is the role of human contamination by environmental chemicals in the development of type 1 diabetes? | The increasing incidence of type 1 diabetes (T1D) in children around the world is unexplained. Even though various environmental chemicals have been linked to the development of type 2 diabetes as well as other autoimmune diseases, the possibility that environmental chemicals may contribute to the development of T1D ha... | ['Autoimmunity', 'California', 'Cross-Sectional Studies', 'Diabetes Mellitus, Type 1', 'Endocrine Disruptors', 'Environmental Exposure', 'Humans', 'Organic Chemicals', 'Risk Factors'] | 21,502,091 | [['G12.450.192'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['D27.505.696.353', 'D27.888.141'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02'... | ['Phenomena and Processes [G]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Metastatic neuroblastoma in the mandible. Report of a case. | The case reported here is that of a metastatic neuroblastoma of the mandible in a 5-year-old boy. This kind of metastasis in the mandible is very rare. Osteolytic jaw defects and unexplainable looseness of the deciduous molars in children should induce a thorough examination with the possibility of a metastatic maligno... | ['Child, Preschool', 'Humans', 'Male', 'Mandibular Neoplasms', 'Neoplasm Metastasis', 'Neuroblastoma'] | 1,061,918 | [['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.149.721.450.583', 'C05.116.231.754.450.583', 'C05.500.499.583', 'C05.500.607.442', 'C07.320.515.583', 'C07.320.610.583'], ['C04.697.650', 'C23.550.727.650'], ['C04.557.465.625.600.590.650.550', 'C04.557.470.670.590.650.550', 'C04.557.580.6... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sine ars scientia nihil est: Leonardo da Vinci and beyond. | The aim of this article is to reflect on the relationship between art and science so far as it concerns a symposium on neurosciences. We undertake a historical overview of that relationship, paying particular attention to the sui generis case of Leonardo da Vinci, who very often is regarded as the man who worked on art... | ['Art', 'Epilepsy', 'Famous Persons', 'History, 15th Century', 'History, 16th Century', 'History, Ancient', 'History, Medieval', 'Humans', 'Neurosciences'] | 18,840,546 | [['K01.093'], ['C10.228.140.490'], ['K01.517.211.506', 'M01.228'], ['K01.400.475.500'], ['K01.400.475.750'], ['K01.400.470'], ['K01.400.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.158.610']] | ['Humanities [K]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[A case of Pneumocystis carinii pneumonia during treatment for miliary tuberculosis]. | A 30-year old man of Myanmar origin was admitted to our hospital because of productive cough, anorexia, weight loss and fever. Sputum smear was strongly positive for M. tuberculosis (Gaffky 6) and sputum culture proved M. tuberculosis. Caseous necrosis with Langhans giant cells was observed in the biopsied specimens of... | ['Adult', 'Humans', 'Male', 'Pneumonia, Pneumocystis', 'Tuberculosis, Miliary'] | 12,607,338 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.703.534.700', 'C01.150.703.770.700', 'C01.748.435.700', 'C01.748.610.675', 'C08.381.472.700', 'C08.381.677.675', 'C08.730.435.700', 'C08.730.610.675'], ['C01.150.252.410.040.552.846.764']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The cingulum and cingulate U-fibers in children and adolescents with autism spectrum disorders. | The cingulum is the major fiber system connecting the cingulate and surrounding medial cortex and medial temporal lobe internally and with other brain areas. It is important for social and emotional functions related to core symptomatology in autism spectrum disorders (ASDs). While the cingulum has been examined in aut... | ['Adolescent', 'Autism Spectrum Disorder', 'Brain Mapping', 'Child', 'Diffusion Tensor Imaging', 'Female', 'Gyrus Cinguli', 'Humans', 'Male', 'Nerve Fibers', 'White Matter'] | 30,941,791 | [['M01.060.057'], ['F03.625.164.113'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['M01.060.406'], ['E01.370.350.578.750', 'E01.370.350.825.500.150.500', 'E01.370.376.537.500', 'E05.629.750'], ['A08.186.211.180.590.500', 'A08.186.211.200.885.287.500.382.500'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prevalence of head deformities in preterm infants at term equivalent age. | INTRODUCTION: Due to a rising number of head deformities in healthy newborns, there has been an increasing interest in nonsynostotic head deformities in children over recent years. Although preterm infants are more likely to have anomalous head shapes than term newborns, there is limited data available on early prevale... | ['Age Factors', 'Cephalometry', 'Cohort Studies', 'Cross-Sectional Studies', 'Germany', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Odds Ratio', 'Plagiocephaly', 'Prevalence', 'Statistics, Nonparametric'] | 24,016,482 | [['N05.715.350.075', 'N06.850.490.250'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A Retrospective Study of Cognitive Improvement Following Electroconvulsive Therapy in Schizophrenia Inpatients. | OBJECTIVES: Findings on the cognitive effect of electroconvulsive therapy (ECT) in individuals with schizophrenia have brought mixed results, with few recent studies beginning to report cognitive improvements after treatment. Cognitive change in inpatients with schizophrenia who were referred for an acute course of ECT... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Attention', 'Cognition', 'Electroconvulsive Therapy', 'Executive Function', 'Female', 'Humans', 'Inpatients', 'Male', 'Mental Status and Dementia Tests', 'Middle Aged', 'Predictive Value of Tests', 'Retrospective Studies', 'Schizophrenia', 'Schizophrenic Psychology'... | 30,628,992 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F02.830.104.214'], ['F02.463.188'], ['F04.570.200.583', 'F04.669.224.300'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['F04.711.513.603'], ['M01.060.116.630'], ['E05.318.370.800.650', 'N05.715.360... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Benign breast disease and cancer. | We report the necessity for thoroughly understanding the physiopathology of benign breast lesions in order to treat each type of lesion adequately. Three groups of women are outlined as a practical approach to this problem. Subadipose mastectomy is proposed to treat heteronodular mastopathy. This operation is compared ... | ['Breast', 'Breast Diseases', 'Breast Neoplasms', 'Female', 'Humans', 'Mastectomy'] | 1,205,685 | [['A01.236'], ['C17.800.090'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.466']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Why is D-serine nephrotoxic and alpha-aminoisobutyric acid protective? | D-Serine selectively causes necrosis of S(3) segments of proximal tubules in rats. This leads to aminoaciduria and glucosuria. Coinjection of the nonmetabolizable amino acid alpha-aminoisobutyric acid (AIB) prevents the tubulopathy. D-serine is selectively reabsorbed in S(3), thereby gaining access to peroxisomal D-ami... | ['Amino Acids', 'Aminoisobutyric Acids', 'Animals', 'D-Amino-Acid Oxidase', 'Dose-Response Relationship, Drug', 'Glucose', 'Glutathione', 'Glycosuria', 'Hydrogen Peroxide', 'Injections, Intraperitoneal', 'Insulin', 'Kidney', 'Kidney Diseases', 'Kidney Tubules, Proximal', 'Loop of Henle', 'Male', 'Oxidation-Reduction', ... | 17,429,029 | [['D12.125'], ['D02.241.081.114.968.249', 'D12.125.070.075', 'D12.125.190.055'], ['B01.050'], ['D08.811.682.664.500.125'], ['G07.690.773.875', 'G07.690.936.500'], ['D09.947.875.359.448'], ['D12.644.456.448'], ['C12.777.934.363', 'C13.351.968.934.363', 'C18.452.394.937'], ['D01.248.497.158.685.750.424', 'D01.339.431.374... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Focal 18F-NaF PET Prostate Activity in the Setting of Prostate Adenocarcinoma. | A 72-year-old man with a family history of prostate cancer and initial diagnosis of favorable intermediate risk prostate cancer via biopsy in 2017 elected for active surveillance. Two years later, he underwent prostate biopsy showing intermediate-risk cT1c Nx Mx lesion with Gleason score 3 + 4 = 7 (5 core positive). Tr... | ['Adenocarcinoma', 'Aged', 'Androgen Antagonists', 'Biopsy', 'Fluorine Radioisotopes', 'Humans', 'Male', 'Neoplasm Grading', 'Positron-Emission Tomography', 'Prostate-Specific Antigen', 'Prostatic Neoplasms', 'Sodium Fluoride', 'Ultrasonography'] | 32,404,713 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['D06.347.065', 'D27.505.696.399.450.065'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D01.496.749.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789.612'],... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
In Rhodobacter sphaeroides, chemotactic operon 1 regulates rotation of the flagellar system 2. | Rhodobacter sphaeroides is able to assemble two different flagella, the subpolar flagellum (Fla1) and the polar flagella (Fla2). In this work, we report the swimming behavior of R. sphaeroides Fla2(+) cells lacking each of the proteins encoded by chemotactic operon 1. A model proposing how these proteins control Fla2 r... | ['Bacterial Proteins', 'Chemotaxis', 'Flagella', 'Gene Expression Regulation, Bacterial', 'Operon', 'Rhodobacter sphaeroides'] | 21,949,068 | [['D12.776.097'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['A11.284.180.290'], ['G05.308.300'], ['G05.360.340.024.686', 'G05.360.340.358.207.500'], ['B03.440.623.700', 'B03.660.050.750.700.700']] | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Life course variation in the relation between maternal marital status and preterm birth. | PURPOSE: Maternal marriage is protective against preterm birth (PTB), whereas advanced maternal age is associated with increased PTB risk. Because relations between social factors and health may vary during the life course, we assessed how the relation between marital status and PTB risk may change with maternal age.ME... | ['Adult', 'Birth Certificates', 'Educational Status', 'Female', 'Humans', 'Logistic Models', 'Marital Status', 'Maternal Age', 'Michigan', 'Odds Ratio', 'Parity', 'Pregnancy', 'Premature Birth', 'Risk Factors', 'Social Environment', 'Young Adult'] | 22,285,870 | [['M01.060.116'], ['E05.318.308.940.250', 'L01.399.250.900.250', 'N04.452.859.132', 'N05.715.360.300.715.175', 'N06.850.520.308.940.250'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Gene expression abnormalities in histologically normal breast epithelium from patients with luminal type of breast cancer. | The gene expression profile of breast cancer has been described as a great breakthrough on the way to comprehend differences in cancer origin, behavior and therapy. However, gene expression profile in histologically normal epithelium (HNEpi) which could harbor genetic abnormalities predisposing breast tissue to develop... | ['Biomarkers, Tumor', 'Breast', 'Breast Neoplasms', 'Epithelium', 'ErbB Receptors', 'Female', 'Genes, Neoplasm', 'Genetic Predisposition to Disease', 'Humans', 'Kallikreins', 'Nerve Tissue Proteins', 'Prognosis', 'Receptors, Nerve Growth Factor', 'Secretoglobins', 'Transcriptome'] | 25,407,308 | [['D23.101.140'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['A10.272'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['G05.360.340.024.340.375'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.7... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Grp1 plays a key role in linking insulin signaling to glut4 recycling. | The glucose transporter type 4 (glut4) is critical for metabolic homeostasis. Insulin regulates glut4 by modulating its expression on the cell surface. This regulation is mainly achieved by targeting the endocytic recycling of glut4. We identify general receptor for 3-phosphoinositides 1 (Grp1) as a guanine nucleotide ... | ['ADP-Ribosylation Factors', 'Animals', 'Glucose Transporter Type 4', 'Hypoglycemic Agents', 'Insulin', 'Mice', 'NIH 3T3 Cells', 'Phosphorylation', 'Proto-Oncogene Proteins c-akt', 'Receptors, Cytoplasmic and Nuclear', 'Signal Transduction'] | 22,609,160 | [['D08.811.277.040.330.300.400.100', 'D12.644.360.525.100', 'D12.776.157.325.515.100', 'D12.776.476.525.100'], ['B01.050'], ['D12.776.157.530.500.500.937', 'D12.776.157.530.937.563.937', 'D12.776.543.585.500.500.937', 'D12.776.543.585.937.625.937'], ['D27.505.696.422'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mucin gene expression and mouse middle ear epithelium. | OBJECTIVES: To investigate the expression of recently identified human mucin genes in an in vitro model of cultured mouse middle ear epithelial cells (MMEEC).METHODS: MMEEC were established, RNA was extracted and primers were designed for RT-PCR to assess for expression of mucin genes Muc1, Muc2, Muc3, Muc4, Muc5AC, Mu... | ['Animals', 'Cells, Cultured', 'Ear, Middle', 'Epithelial Cells', 'Gene Expression Regulation', 'Humans', 'In Vitro Techniques', 'Mice', 'Models, Animal', 'Mucins', 'Otitis Media', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sensitivity and Specificity'] | 20,846,498 | [['B01.050'], ['A11.251'], ['A09.246.397'], ['A11.436'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.598'], ['D12.776.395.560.631'], ['C09.218.705.663'], ['E05.393.620.500.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Worldwide Effects of Coronavirus Disease Pandemic on Tuberculosis Services, January-April 2020. | Coronavirus disease has disrupted tuberculosis services globally. Data from 33 centers in 16 countries on 5 continents showed that attendance at tuberculosis centers was lower during the first 4 months of the pandemic in 2020 than for the same period in 2019. Resources are needed to ensure tuberculosis care continuity ... | ['Betacoronavirus', 'COVID-19', 'Continuity of Patient Care', 'Coronavirus Infections', 'Facilities and Services Utilization', 'Global Health', 'Humans', 'Pandemics', 'Pneumonia, Viral', 'SARS-CoV-2', 'Tuberculosis'] | 32,917,293 | [['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['C01.925.782.600.550.200'], ['E05.318.740.388', 'H01.548.832.625', 'N04.452... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[Detection of urinary polyamine by a new enzymatic differential assay. (II). Comparison with conventional method]. | A new method of determining urinary polyamine concentration was compared with other techniques, namely, high pressure liquid chromatography (HPLC) and a polyamine test-enzyme kit. The values obtained by the new method, HPLC, and polyamine test-enzyme kit correlated well for all the fractions: diamine, spermidine and sp... | ['Chromatography, High Pressure Liquid', 'Diamines', 'Humans', 'Methods', 'Oxidoreductases Acting on CH-NH Group Donors', 'Polyamines', 'Reagent Kits, Diagnostic', 'Spermidine', 'Spermine'] | 3,728,239 | [['E05.196.181.400.300'], ['D02.092.782.258'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['D08.811.682.662'], ['D02.092.782'], ['D27.505.259.875', 'D27.720.470.410.680', 'E07.720'], ['D02.092.211.415.701.801', 'D02.092.782.677'], ['D02.092.211.415.701.801.821', 'D02.092.782.802']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Outcome of very-low-birth-weight infants who received epinephrine in the delivery room. | BACKGROUND: In recent years, there has been an increase in the number of very low birth weight (VLBW) infants and an improvement in their survival. However, there are no specific recommendations regarding the use of resuscitative efforts for VLBW infants, and there is scant data in the literature on morbidity and morta... | ['Cardiopulmonary Resuscitation', 'Delivery Rooms', 'Epinephrine', 'Female', 'Follow-Up Studies', 'Heart Arrest', 'Humans', 'Infant, Newborn', 'Infant, Very Low Birth Weight', 'Intensive Care Units, Neonatal', 'Male', 'Retrospective Studies', 'Sympathomimetics', 'Treatment Outcome'] | 21,272,985 | [['E02.365.647.110'], ['N02.278.388.150'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C14.280.383'], ['B01.050.150.900.649.313.988.400.112.40... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mapping of functional regions in the amino-terminal portion of the herpes simplex virus ICP27 regulatory protein: importance of the leucine-rich nuclear export signal and RGG Box RNA-binding domain. | Infected-cell protein 27 (ICP27) is an essential herpes simplex virus type 1 (HSV-1) regulatory protein that activates a subset of viral delayed-early and late genes, at least in part through posttranscriptional mechanisms. Previous studies have shown that the amino (N)-terminal half of the protein contains important f... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Binding Sites', 'Cell Nucleus', 'Chlorocebus aethiops', 'DNA Replication', 'DNA, Viral', 'Gene Expression', 'Genes, Viral', 'Immediate-Early Proteins', 'Leucine', 'Molecular Sequence Data', 'Mutation', 'Peptide Mapping', 'Protein Structure, Tertiary', 'RNA, Viral', '... | 12,414,929 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['G02.111.225', 'G05.226'], ['D13.444.308.568'], ['G05.297'], ['G05.360.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Functional consequence of a novel Y129C mutation in a patient with two contradictory melanocortin-2-receptor mutations. | CONTEXT: Familial glucocorticoid deficiency (FGD) is a rare autosomal recessive disease, characterised by isolated glucocorticoid deficiency in the absence of mineralocorticoid deficiency. Inactivating mutations in the ACTH receptor (melanocortin-2-receptor, MC2R) are well described and account for approximately 25% of... | ['Adrenocorticotropic Hormone', 'Alleles', 'Animals', 'Blotting, Western', 'CHO Cells', 'Cell Line', 'Cricetinae', 'Cricetulus', 'DNA Mutational Analysis', 'Humans', 'Immunoprecipitation', 'Infant, Newborn', 'Microscopy, Confocal', 'Mutation', 'Protein Folding', 'Receptor, Melanocortin, Type 2', 'Receptors, Cell Surfac... | 19,151,134 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['G05.360.340.024.340.030'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Alterations of interferon production in a mouse model of thermal injury. | The effect of thermal injury on the response of interferon (IFN) production in vivo and in vitro after stimulation with eight representative inducers was investigated in a mouse model. The response of mice to immune IFN (IFN-gamma) inducers, staphylococcal enterotoxin A, concanavalin A, and a specific antigen for BCG-s... | ['Animals', 'Burns', 'Concanavalin A', 'Disease Models, Animal', 'Immune Tolerance', 'Interferon Inducers', 'Interferons', 'Mice', 'Mice, Inbred BALB C', 'Newcastle disease virus', 'Poly I-C', 'Staphylococcal Protein A', 'Time Factors', 'Tuberculin'] | 6,181,145 | [['B01.050'], ['C26.200'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G12.535.425'], ['D27.505.696.477.828'], ['D12.644.276.374.440', 'D12.776.467.374.440', 'D23.529.374.440'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Rotator cuff ruptures with predominant involvement of the subscapular tendon]. | Among the all rotator cuff tears, the subscapularis lesions are quite rare. But a careful analysis leads to recognize them specially in case of antero-medial impingement between the coracoid process and the head of the humerus. This study of 25 observations where the rupture of the subscapularis was the predominant les... | ['Adult', 'Aged', 'Female', 'Humans', 'Male', 'Middle Aged', 'Rotator Cuff', 'Rotator Cuff Injuries', 'Shoulder Injuries', 'Tendon Injuries'] | 7,805,504 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.567.912', 'A02.880.700'], ['C26.761.340', 'C26.803.063', 'C26.874.400'], ['C26.803'], ['C26.874']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Recruitment and retention of GI nurses: hiring, firing, and surviving. | Nursing turnover is costly for GI units, both financially and emotionally. The emphasis at Duke University Medical Center is changing from recruitment of GI nurses to searching for methods of retaining staff and building team morale. Recruitment and retention survey results are discussed in this article and retention s... | ['Career Mobility', 'Endoscopy, Gastrointestinal', 'Hospital Units', 'Job Satisfaction', 'Nursing Staff, Hospital', 'Personnel Management', 'Personnel Turnover', 'Surveys and Questionnaires', 'Workforce'] | 8,218,449 | [['N01.824.245.175', 'N01.824.547.330'], ['E01.370.372.250.250', 'E01.370.388.250.250.250', 'E04.210.240.250', 'E04.502.250.250.250'], ['N02.278.388'], ['F02.784.692.425'], ['M01.526.485.680.490', 'M01.526.485.740.523', 'N02.360.680.490', 'N02.360.740.523'], ['N04.452.677'], ['N04.452.677.680'], ['E05.318.308.980', 'N0... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Named Groups [M]'] | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Liver Transplantation and Abuse of Drugs and Alcohol: A Correlation Between Scales of the MMPI-2. | BACKGROUND: Clinical practice requires an accurate psychological assessment of subjects with clinical history of alcohol abuse and/or substance abuse (abuse history [AH]) for therapeutic choice. This study aims to identify significant correlations between the Minnesota Multiphasic Personality Inventory (MMPI)-2 scales ... | ['Alcoholism', 'Female', 'Humans', 'Liver Transplantation', 'MMPI', 'Male', 'Middle Aged', 'Patient Compliance', 'Personality', 'Substance-Related Disorders', 'Surveys and Questionnaires', 'Waiting Lists'] | 27,109,962 | [['C25.775.100.250', 'F03.900.100.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['F04.711.647.513.607'], ['M01.060.116.630'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600'], ['F01.752'], ['C25.775'... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Yellow fever outbreak affecting Alouatta populations in southern Brazil (Rio Grande do Sul State), 2008-2009. | The natural transmission cycle of Yellow Fever (YF) involves tree hole breeding mosquitoes and a wide array of nonhuman primates (NHP), including monkeys and apes. Some Neotropical monkeys (howler monkeys, genus Alouatta) develop fatal YF virus (YFV) infections similar to those reported in humans, even with minimum exp... | ['Alouatta', 'Animals', 'Brazil', 'Disease Outbreaks', 'Female', 'Humans', 'Male', 'Monkey Diseases', 'Yellow Fever'] | 22,020,690 | [['B01.050.150.900.649.313.988.400.600.075.050.075'], ['B01.050'], ['Z01.107.757.176'], ['N06.850.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C22.735.500'], ['C01.920.500.980', 'C01.925.081.980', 'C01.925.782.350.250.980', 'C01.925.782.417.881']] | ['Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Right heart free-floating thrombus in a pregnant woman with massive pulmonary embolism: a case of 'emboli in transit'. | The mainstay of treatment for massive pulmonary embolism in nonpregnant individuals is urgent thrombolytic therapy, but experience with these drugs in pregnancy is limited. We report a case of a 36-year-old woman at 27 weeks' gestation who was admitted with a massive, life-threatening pulmonary embolism. The diagnosis ... | ['Adult', 'Cesarean Section', 'Echocardiography', 'Female', 'Humans', 'Pregnancy', 'Pulmonary Embolism', 'Thrombolytic Therapy', 'Thrombosis', 'Tissue Plasminogen Activator', 'Treatment Outcome'] | 21,135,590 | [['M01.060.116'], ['E04.520.252.500'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['C08.381.746', 'C14.907.355.350.700'], ['E02.319.913'], ['C14.907.355.830'], ['D08.811.277.656.300.760.875', 'D08.811.277.656.959.350.875',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Electrophysiological correlates of voice memory for young and old speakers in young and old listeners. | Faces of one's own-age group are easier to recognize than other-age faces. Using behavioral measures and EEG, we studied whether an own-age bias (OAB) also exists in voice memory. Young (19 - 26 years) and old (60-75 years) participants studied young (18-25 years) and old (60-77 years) unfamiliar voices from short sent... | ['Adult', 'Aged', 'Aging', 'Auditory Perception', 'Correlation of Data', 'Electroencephalography', 'Evoked Potentials', 'Female', 'Hearing', 'Humans', 'Male', 'Memory', 'Middle Aged', 'Recognition, Psychology', 'Time Factors', 'Voice', 'Young Adult'] | 28,802,769 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['F02.463.593.071', 'G07.888.125'], ['H01.548.832.500'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['F02.830.816.263', 'G07.888.500', 'G11.561.790.263'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Cognitive abilities and lipomyelomeningocele. | Ten children with lipomyelomeningocele were evaluated with the WISC--R, the Wide Range Achievement Test--Revised, the Developmental Test of Visual-motor Integration, and the Child Behavior Checklist. These children were consecutive referrals to a birth defects clinic. Unlike their meningomyelocele counterparts, as a gr... | ['Child', 'Cognition Disorders', 'Educational Status', 'Female', 'Humans', 'Intelligence', 'Lipoma', 'Lumbar Vertebrae', 'Male', 'Meningomyelocele', 'Neuropsychological Tests', 'Sacrum', 'Spina Bifida Occulta', 'Spinal Neoplasms'] | 8,234,598 | [['M01.060.406'], ['F03.615.250'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.543'], ['C04.557.450.550.400'], ['A02.835.232.834.519'], ['C10.500.680.610', 'C16.131.666.680.610'], ['F04.711.513'], ['A02.835.232.834.717'], ['C10.500.680.800.750', 'C16.131.666.680.800.750'], ['C04.588.149.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Candidate gene analysis for determinacy in pigeonpea (Cajanus spp.). | KEY MESSAGE: We report a likely candidate gene, CcTFL1, for determinacy in pigeonpea through candidate gene sequencing analysis, mapping, QTL analysis together with comparative genomics and expression profiling. Pigeonpea (Cajanus cajan) is the sixth most important legume crop grown on ~5 million hectares globally. Det... | ['Base Sequence', 'Cajanus', 'Chromosome Mapping', 'Comparative Genomic Hybridization', 'Flowers', 'Gene Expression Profiling', 'Genes, Plant', 'Genetic Linkage', 'Genotype', 'Molecular Sequence Data', 'Phaseolus', 'Phenotype', 'Polymorphism, Single Nucleotide', 'Quantitative Trait Loci', 'Soybeans'] | 25,331,300 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.650.940.800.575.912.250.401.094'], ['E05.393.183'], ['E05.393.285.240', 'E05.393.520.500', 'E05.393.661.187'], ['A18.024.249.500'], ['E05.393.332'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.348'], ['G05.380'], ['L01.453.245.667'], ['B01.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Assessment of unmet needs and the lack of generalizability in the design of randomized controlled trials for scleroderma treatment. | OBJECTIVE: To determine the generalizability of randomized controlled trials (RCTs) in the treatment of systemic sclerosis (SSc) using the Canadian Scleroderma Research Group (CSRG) database.METHODS: We identified articles related to SSc published from 1958 to 2006. Key points on trial design were recorded. The inclusi... | ['Data Interpretation, Statistical', 'Female', 'Humans', 'Male', 'Middle Aged', 'Randomized Controlled Trials as Topic', 'Research Design', 'Scleroderma, Systemic', 'Treatment Outcome'] | 18,438,906 | [['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365.500'], ['E05.581.500', 'H01.770.644.728'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Role of reactive oxygen species (ROS) in Mycobacterium bovis bacillus Calmette Gu?rin-mediated up-regulation of the human cathelicidin LL-37 in A549 cells. | The human cathelicidin LL-37 is one of the major antimicrobial peptides of the non-specific innate immune system in Mycobacterium tuberculosis infection. Its expression has been reported in epithelial cells infected with mycobacteria. However, the underlying molecular mechanisms by which Mycobacterium bovis bacillus Ca... | ['Antimicrobial Cationic Peptides', 'Cell Line', 'Epithelial Cells', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Humans', 'Mycobacterium bovis', 'Reactive Oxygen Species', 'Reverse Transcriptase Polymerase Chain Reaction', 'Up-Regulation'] | 19,729,059 | [['D12.644.050', 'D12.776.543.695.054'], ['A11.251.210'], ['A11.436'], ['E05.393.332'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.510.024.962.500.402', 'B03.510.460.400.410.552.552.402'], ['D01.339.431', 'D01.650.775'], ['E05.393.620.500.725'], ['G02.111.905', 'G05.308.850', 'G07.690.773.998']... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunohistochemical molecular gene expression profile of metastatic brain tumor as a potent personalized medicine. | Recent progress in molecule-targeting therapy may yield personalized therapeutic strategies for patients with metastatic brain tumors (MBT), the most frequently encountered intracranial tumors. For this purpose, we investigated the molecular expression profile of MBT to establish the pathological basis for personalized... | ['Aged', 'Aged, 80 and over', 'Antineoplastic Agents, Alkylating', 'Brain', 'Brain Neoplasms', 'DNA Modification Methylases', 'DNA Repair Enzymes', 'Dacarbazine', 'ErbB Receptors', 'Female', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', '... | 23,180,004 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.519.124.035', 'D27.505.954.248.150', 'D27.888.569.035.035'], ['A08.186.211'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['D08.811.150.240', 'D08.811.913.555.500.350'], ['D08.811.074'], ['D02.925.200', 'D03.383.129.308.240'], ['D08.811.913.696... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Physical activity, symptoms of chest pain and dyspnea in patients with ischemic heart disease in relation to age before and two years after coronary artery bypass grafting. | BACKGROUND: To describe limitation of physical activity, cause of limitation of physical activity and symptoms of dyspnea and chest pain in relation to age before and 2 years after coronary artery bypass grafting (CABG).METHODS: All patients from Western Sweden who underwent CABG without concomitant procedures during 3... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Angina Pectoris', 'Coronary Artery Bypass', 'Dyspnea', 'Exercise', 'Exercise Tolerance', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Myocardial Ischemia', 'Prospective Studies', 'Surveys and Questionnaires', 'Time Factors'] | 11,292,928 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['C08.618.326', 'C23.888.852.371'], ['G11.427.410.698.277', 'I03.350'], ['G11.... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Expression and activation of insulin receptor substrate-1 in endometrial carcinoma]. | OBJECTIVE: To investigate the mRNA, protein expression and tyrosine phosphorylation of insulin receptor substrate-1 (IRS-1) in endometrial carcinoma.METHODS: Sixty-three endometrial carcinoma (EC) patients, 21 endometrial atypical hyperplasia (AHE) patients and 22 normal control (NE) entered this study. Their clinical ... | ['Adenocarcinoma', 'C-Peptide', 'Case-Control Studies', 'Endometrial Hyperplasia', 'Endometrial Neoplasms', 'Endometrium', 'Female', 'Humans', 'Insulin Receptor Substrate Proteins', 'Lymphatic Metastasis', 'Middle Aged', 'Neoplasm Staging', 'Phosphorylation', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Re... | 19,035,139 | [['C04.557.470.200.025'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C13.351.500.852.228'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['A05.360.319.679.490'], ['B01.050.150.900.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
FABP2, LEPR223, LEP656, and FTO Polymorphisms: Effect on Weight Loss 2 Years After Bariatric Surgery. | PURPOSE: Differences in weight loss outcomes after bariatric surgery may be related to individual preoperative characteristics. The aim of this study was to evaluate the potential effect of fatty acid binding protein-2 (rs1799883), leptin receptor (LEP223, rs1137101 and LEP656, rs1805094), and fat mass and obesity-rela... | ['Adult', 'Alpha-Ketoglutarate-Dependent Dioxygenase FTO', 'Bariatric Surgery', 'Brazil', 'Fatty Acid-Binding Proteins', 'Genotype', 'Humans', 'Middle Aged', 'Obesity, Morbid', 'Prospective Studies', 'Receptors, Leptin', 'Weight Loss'] | 29,744,713 | [['M01.060.116'], ['D08.811.074.062.968', 'D08.811.682.662.582.242', 'D08.811.682.690.416.139.992'], ['E02.650.500.062', 'E04.062'], ['Z01.107.757.176'], ['D12.776.157.170'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C18.654.726.500.700', 'C23.888.144.699.500.500', 'E01.370.60... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Lipoatrophia semicircularis in the male. Coincidence of arterial variations and micro-traumas as a possible disease cause]. | Semicircular lipoatrophy is a new entity with horizontal depressions involving half the circumference of thigh, on the antero-lateral aspect. After seven female patients we observed this condition for the first time in the male. Therefore semicircular lipoatrophy is not specific to the female. The cause could not be de... | ['Adipose Tissue', 'Adult', 'Arteries', 'Atrophy', 'Chronic Disease', 'Diagnosis, Differential', 'Humans', 'Male', 'Regional Blood Flow', 'Skin Diseases', 'Thigh'] | 659,107 | [['A10.165.114'], ['M01.060.116'], ['A07.015.114'], ['C23.300.070'], ['C23.550.291.500'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.330.100.780'], ['C17.800'], ['A01.378.610.750']] | ['Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Kinetic Characterization of PA1225 from Pseudomonas aeruginosa PAO1 Reveals a New NADPH:Quinone Reductase. | The pa1225 gene of Pseudomonas aeruginosa strain PAO1 was cloned, and the resulting enzyme (PA1225) was purified and revealed to be an NADPH:quinone reductase. By using kinetics, fluorescence, and mass spectrometric analyses, PA1225 was shown to utilize FAD to transfer a hydride ion from NADPH to quinones. The enzyme c... | ['Benzoquinones', 'Flavins', 'Kinetics', 'NAD', 'NAD(P)H Dehydrogenase (Quinone)', 'NADP', 'Oxidation-Reduction', 'Oxidoreductases', 'Pseudomonas aeruginosa', 'Quinones'] | 29,715,013 | [['D02.806.250'], ['D03.633.100.733.315', 'D03.633.300.507', 'D08.211.474', 'D23.767.405'], ['G01.374.661', 'G02.111.490'], ['D03.633.100.759.646.138.694', 'D08.211.589', 'D13.695.667.138.694', 'D13.695.827.068.694'], ['D08.811.682.608.800.500'], ['D03.633.100.759.646.138.749', 'D08.211.625', 'D13.695.667.138.749', 'D1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fluorescence turn-on detection of glucose via the Ag nanoparticle mediated release of a perylene probe. | A novel fluorescence turn-on strategy for glucose sensing is demonstrated. The fluorescence of a perylene probe could be quenched by the silver nanoparticles (Ag NPs). The Ag NPs could be etched by H2O2 generated from the enzymatic oxidation of glucose. And efficient probe fluorescence recovery was detected. | ['Chemistry Techniques, Analytical', 'Fluorescent Dyes', 'Glucose', 'Hydrogen Peroxide', 'Metal Nanoparticles', 'Oxidation-Reduction', 'Perylene', 'Silver', 'Spectrometry, Fluorescence'] | 25,763,414 | [['E05.196'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D09.947.875.359.448'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['J01.637.512.600.500'], ['G02.700', 'G03.295.531'], ['D02.455.426.559.847.149.700', 'D02.455.426.559.847.680.500', 'D04.615.149.700', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Cross-regulation in Vibrio parahaemolyticus: compensatory activation of polar flagellar genes by the lateral flagellar regulator LafK. | Gene organization and hierarchical regulation of the polar flagellar genes of Vibrio parahaemolyticus, Vibrio cholerae, and Pseudomonas aeruginosa appear highly similar, with one puzzling difference. Two sigma(54)-dependent regulators are required to direct different classes of intermediate flagellar gene expression in... | ['Amino Acid Sequence', 'Bacterial Proteins', 'DNA-Binding Proteins', 'DNA-Directed RNA Polymerases', 'Flagella', 'Gene Expression Regulation, Bacterial', 'Molecular Sequence Data', 'Mutation', 'Pseudomonas aeruginosa', 'RNA Polymerase Sigma 54', 'Sigma Factor', 'Vibrio cholerae', 'Vibrio parahaemolyticus'] | 15,175,315 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['D12.776.260'], ['D08.811.913.696.445.735.270'], ['A11.284.180.290'], ['G05.308.300'], ['L01.453.245.667'], ['G05.365.590'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050'], ['D08.811.913.696.445.735.270.887', 'D12.776.097.698'], ['D12.776.930.80... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Pallor of the optic papilla--an early sign of glaucoma. A clinical controlled study of optic disk pallor and papillar cupping in glaucoma simplex, ocular hypertension and normal eyes with the optic nerve head analyzer]. | Double examinations of 99 eyes (34 healthy, 12 with ocular hypertension, 53 with primary open-angle glaucoma) were performed with the Optic Nerve Head Analyzer to evaluate whether an increase in disk pallor or in the cup-disk ratio (CDR) is the earlier sign of glaucoma. In eyes with primary open-angle glaucoma the CDR ... | ['Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Middle Aged', 'Ocular Hypertension', 'Optic Disk'] | 2,761,191 | [['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['M01.060.116.630'], ['C11.525'], ['A08.800.800.120.680.660', 'A09.371.729.690']] | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Silicon Alleviates Changes in the Source-Sink Relationship of Wheat Plants Infected by Pyricularia oryzae | Blast, caused by Pyricularia oryzae, has become a devastating disease on wheat in several countries worldwide. Growers need alternative methods for blast management, and silicon (Si) stands out for its potential to decrease the intensity of important diseases in several crops. This study investigated the effect of Si o... | ['Ascomycota', 'Chlorophyll A', 'Photosynthesis', 'Plant Diseases', 'Plant Leaves', 'Silicon', 'Triticum'] | 30,794,486 | [['B01.300.107'], ['D03.383.129.578.840.374.140', 'D03.633.400.909.374.140', 'D04.345.783.374.140'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G03.800.700', 'G15.568'], ['G15.610'], ['A18.024.812'], ['D01.268.513.937'], ['B01.650.940.800.575.912.250.822.918']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
On the role of the two extracytoplasmic substrate-binding domains in the ABC transporter OpuA. | Members of two transporter families of the ATP-binding cassette (ABC) superfamily use two or even four extracytoplasmic substrate-binding domains (SBDs) for transport. We report on the role of the two SBDs in the translocation cycle of the ABC transporter OpuA from Lactococcus lactis. Heterooligomeric OpuA complexes wi... | ['ATP-Binding Cassette Transporters', 'Adenosine Triphosphatases', 'Bacterial Proteins', 'Betaine', 'Lactococcus lactis', 'Protein Structure, Tertiary'] | 14,609,945 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D08.811.277.040.025'], ['D12.776.097'], ['D02.092.877.883.077', 'D02.675.276.125'], ['B03.353.750.737.500.400', 'B03.510.400.800.500.400', 'B03.510.550.737.500.400'], ['G02.111.570.820.709.610']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of acetylcholine on time-dependent currents in sheep cardiac Purkinje fibers. | Voltage clamp experiments were carried out on sheep Purkinje fibers to determine the effect of Ach on the time-dependent currents. On the pacemaker current (iK2) Ach 10(-6) mol . l(-1) had the following effects: shift of the activation curve by a few mV in the depolarizing direction, without change in the rectifier rat... | ['Acetylcholine', 'Animals', 'Electrophysiology', 'Heart Conduction System', 'In Vitro Techniques', 'Kinetics', 'Purkinje Fibers', 'Sheep', 'Time Factors'] | 7,191,987 | [['D02.092.211.111'], ['B01.050'], ['H01.158.344.528', 'H01.158.782.236'], ['A07.541.409'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['A07.541.409.683'], ['B01.050.150.900.649.313.500.380.791'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A 23-year review of the management of acute retention of urine: progressing or regressing? | A retrospective review of all patients in Oxford under the care of one consultant urologist (GJF) who presented on alternate years over a 23-year period with acute retention of urine was undertaken. Data were collected on the: (i) number of patients discharged from hospital with an in-dwelling catheter; (ii) duration o... | ['Acute Disease', 'Aged', 'Aged, 80 and over', 'Catheters, Indwelling', 'Humans', 'Male', 'Medical Audit', 'Middle Aged', 'Prostatectomy', 'Prostatic Hyperplasia', 'Retrospective Studies', 'Time Factors', 'Urinary Catheterization', 'Urinary Retention', 'Waiting Lists'] | 11,041,033 | [['C23.550.291.125'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E07.132.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.250.500', 'N05.700.175.500'], ['M01.060.116.630'], ['E04.950.774.860.625'], ['C12.294.565.500'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Renal transplantation in HIV-infected patients in Spain]. | HIV infection has experienced dramatic improvement in morbidity and mortality with the highly active antiretroviral therapy (HAART). This prompted a reevaluation of organ-solid transplantation as a treatment option for HIV-infected patients. Some trials in the United States have shown that one- and 2-year graft and pat... | ['Adult', 'Anti-HIV Agents', 'Antiretroviral Therapy, Highly Active', 'CD4 Lymphocyte Count', 'Drug Interactions', 'Female', 'Follow-Up Studies', 'Graft Rejection', 'HIV Infections', 'HIV Protease Inhibitors', 'Humans', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Life Expectancy', 'Male', 'Middle Aged', 'Post... | 16,649,432 | [['M01.060.116'], ['D27.505.954.122.388.077.088'], ['E02.319.310.075'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.500.150', 'G04.140.107.595.500.150', 'G09.188.105.595.500.150'], ['G07.690.773.968'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Turbinate-septal suture for middle turbinate medialization: a prospective randomized trial. | OBJECTIVES/HYPOTHESIS: One of the primary goals of endoscopic sinus surgery (ESS) is to create widely patent paranasal sinus ostia, but lateralization of the middle turbinate (MT) after ESS can obstruct otherwise patent ethmoid and maxillary sinuses. The aim of this study was to evaluate the effectiveness of turbinate-... | ['Adolescent', 'Adult', 'Bandages', 'Double-Blind Method', 'Endoscopy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nasal Septum', 'Paranasal Sinuses', 'Postoperative Complications', 'Prospective Studies', 'Reoperation', 'Rhinitis', 'Sinusitis', 'Suture Techniques', 'Tissue Adhesions', 'Tomography, X-Ray Computed', 'Tu... | 25,041,807 | [['M01.060.057'], ['M01.060.116'], ['E07.101'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A04.531.591'], ['A04.531.621'], ['C23.550.767'], ['E05.318.372.500.750.625', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
DNA image cytometric measurement as a surrogate end point biomarker in a phase I trial of alpha-difluoromethylornithine for cervical intraepithelial neoplasia. | Cervical intraepithelial neoplasia grade 3 (CIN 3) is considered a high-risk precursor of invasive cervical cancer. alpha-Difluoromethylornithine (DFMO) is a promising antiproliferative chemopreventive agent. The purpose of this study was to evaluate image cytometric measurement of nuclear DNA (ICM-DNA) as a surrogate ... | ['Adult', 'Anticarcinogenic Agents', 'Antineoplastic Agents', 'Cervical Intraepithelial Neoplasia', 'Clinical Trials, Phase I as Topic', 'DNA, Neoplasm', 'Eflornithine', 'Female', 'Humans', 'Image Cytometry', 'Image Processing, Computer-Assisted', 'Statistics, Nonparametric', 'Uterine Cervical Neoplasms'] | 9,332,769 | [['M01.060.116'], ['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['D27.505.954.248'], ['C04.557.470.200.240.250'], ['E05.318.372.250.250.200', 'N05.715.360.330.250.250.200', 'N06.850.520.450.250.250.200'], ['D13.444.308.425'], ['D12.125.068.665.340', 'D12.125.095.765.340'], ['B01.050.150.900.649.313... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The far side: the meta functions of humanitarianism in a globalised world. | This paper explores the meta functions of humanitarianism--that is, the functions that, as an ideology, a movement and a profession, it performs, wittingly or unwittingly, in the early twenty-first century. The term humanitarianism is used as shorthand to encompass a complex set of currents of thought, actions and inst... | ['Altruism', 'Capitalism', 'Colonialism', 'Disaster Planning', 'Humans', 'Internationality', 'Interpersonal Relations', 'Motivation', 'Organizations', 'Philosophy', 'Politics', 'Relief Work', 'Rescue Work'] | 20,132,266 | [['F01.145.813.090'], ['I01.261.100', 'I01.696.100'], ['I01.696.116'], ['N06.230.100.035'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615'], ['F01.829.401'], ['F01.658', 'F01.752.543.500.750'], ['N03.540'], ['K01.752'], ['I01.738'], ['I01.880.787.839', 'N06.230.100.300'], ['N06.230.100.350']] | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
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