Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
An additive/subtractive genotypic score as a determinant of the virological response to didanosine in HIV-1 infected patients. | OBJECTIVE: To assess the genotypic determinants of the virological response (VR) to didanosine (ddI) in nucleoside reverse transcriptase inhibitors (NRTI)-experienced patients.METHODS: Human immunodeficiency virus type 1 (HIV-1) genotype was determined at baseline in 74 ddI-naive-patients with baseline viral load >500 ... | ['Algorithms', 'Anti-HIV Agents', 'Didanosine', 'Drug Resistance, Viral', 'Genotype', 'HIV Infections', 'HIV-1', 'Humans', 'Multivariate Analysis', 'Mutation', 'RNA, Viral', 'Retrospective Studies', 'Reverse Transcriptase Inhibitors', 'Time Factors', 'Viral Load'] | 16,513,416 | [['G17.035', 'L01.224.050'], ['D27.505.954.122.388.077.088'], ['D03.633.100.759.590.616.130', 'D13.570.230.500.090', 'D13.570.583.616.130', 'D13.570.800.573.130'], ['G06.225.420', 'G06.920.225', 'G07.690.773.984.269.420'], ['G05.380'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.4... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Mortality in Glasgow and Edinburgh: a paradigm of inequality in health. | STUDY OBJECTIVE: The aim was to describe, predict, and interpret mortality in Glasgow and Edinburgh.DESIGN: The study was an analysis of all cause and cause specific mortality data for quinquennia based on census years between 1931 and 1981, linking age and sex specific mortality rates by year of birth, for people dyin... | ['Adult', 'Age Factors', 'Aged', 'Cross-Sectional Studies', 'Disease Susceptibility', 'Female', 'Health Promotion', 'Humans', 'Male', 'Middle Aged', 'Mortality', 'Risk Factors', 'Scotland', 'Sex Factors', 'Socioeconomic Factors'] | 1,479,319 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C23.550.291.687', 'G07.100.250'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.30... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Keratopathy associated with intracorneal glass. | A progressive nonedematous keratopathy developed in a 36-year-old patient after she was struck in the eye by glass fragments. Biopsy material that was examined by electron microscopy and electron beam microanalysis demonstrated the presence of intracorneal glass fragments, which could not be detected clinically. Retain... | ['Adult', 'Cornea', 'Corneal Diseases', 'Corneal Injuries', 'Electron Probe Microanalysis', 'Eye Foreign Bodies', 'Female', 'Glass', 'Humans', 'Microscopy, Electron'] | 7,236,088 | [['M01.060.116'], ['A09.371.060.217'], ['C11.204'], ['C10.900.300.284.250.124', 'C11.204.284', 'C11.297.374', 'C26.915.300.425.250.124'], ['E01.370.350.515.402.250', 'E05.196.867.800.360', 'E05.595.402.250', 'E05.799.830.360'], ['C10.900.300.284.250.260', 'C26.392.421', 'C26.915.300.425.250.260'], ['J01.637.437'], ['B0... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
A case of survival after cardiac arrest and 3½ hours of resuscitation. | Although survival rates after cardiac arrest remain low, new techniques are improving patients' outcomes. We present the case of a 40-year-old man who survived a cardiac arrest that lasted approximately 3½ hours. Resuscitation was performed with strict adherence to American Heart Association/American College of Cardiol... | ['Adult', 'Cardiopulmonary Resuscitation', 'Extracorporeal Membrane Oxygenation', 'Heart Arrest', 'Heart Transplantation', 'Heart-Assist Devices', 'Humans', 'Hypothermia, Induced', 'Kidney Transplantation', 'Length of Stay', 'Male', 'Renal Insufficiency', 'Survivors', 'Time Factors', 'Treatment Outcome'] | 24,808,789 | [['M01.060.116'], ['E02.365.647.110'], ['E02.880.301', 'E04.292.451'], ['C14.280.383'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.258.750'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bacterial lipopolysaccharide (LPS)-specific antibodies in commercial human immunoglobulin preparations: superior antibody content of an IgM-enriched product. | The anti-LPS antibody content of commercial intravenous immunoglobulins was examined by quantitative ELISA using LPS preparations from Escherichia coli, Klebsiella and Pseudomonas aeruginosa O serotypes occurring most frequently in gram-negative septicaemia. Three IgG products from different manufacturers and one IgM-e... | ['Antibodies, Bacterial', 'Drug Contamination', 'Humans', 'Immunoglobulin M', 'Lipopolysaccharides'] | 9,472,665 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['N06.850.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.574', 'D12.776.124.790.651.114.619.574', 'D12.776.377.715.548.114.619.574'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Roll up nanowire battery from silicon chips. | Here we report an approach to roll out Li-ion battery components from silicon chips by a continuous and repeatable etch-infiltrate-peel cycle. Vertically aligned silicon nanowires etched from recycled silicon wafers are captured in a polymer matrix that operates as Li(+) gel-electrolyte and electrode separator and peel... | ['Copper', 'Electric Power Supplies', 'Electrodes', 'Electronics', 'Equipment Design', 'Lithium', 'Metal Nanoparticles', 'Nanotechnology', 'Nanowires', 'Polymers', 'Refuse Disposal', 'Silicon'] | 22,949,696 | [['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['E07.305.124'], ['E07.305.250'], ['H01.671.293'], ['E05.320'], ['D01.268.549.450', 'D01.268.557.290', 'D01.552.528.480', 'D01.552.547.290'], ['J01.637.512.600.500'], ['H01.603', 'J01.897.520.600'], ['J01.637.512.925'], ['D05.750', 'D25.720', 'J01.637.051.720'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Pathological evaluation of differentiated thyroid cancer in patients with positive serum thyroglobulin and negative iodine scan. | OBJECTIVE: There is no investigation that emphasizes the pathology of DTC (differentiated thyroid cancer) patients with positive Tg and negative iodine scan. The present study was performed to assess the pathology of these patients.MATERIALS AND METHODS: In this retrospective study, the records of 500 patients with dif... | ['Adolescent', 'Adult', 'Aged', 'Carcinoma', 'Carcinoma, Papillary', 'Female', 'Humans', 'Iodine Radioisotopes', 'Male', 'Middle Aged', 'Radiopharmaceuticals', 'Thyroglobulin', 'Thyroid Cancer, Papillary', 'Thyroid Neoplasms', 'Thyroidectomy', 'Whole Body Imaging', 'Young Adult'] | 25,010,624 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['M01.060.116.630'], ['D27.505.259.843', 'D27.505.519.871', 'D27.720.470.410.65... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cells. | A defect in RelB, a member of the Rel/nuclear factor (NF)-kappa B family of transcription factors, affects antigen presenting cells and the formation of lymphoid organs, but its role in T lymphocyte differentiation is not well characterized. Here, we show that RelB deficiency in mice leads to a selective decrease of NK... | ['Animals', 'Antigens, CD1', 'Antigens, CD1d', 'Cell Differentiation', 'Cells, Cultured', 'Chimera', 'Fibroblasts', 'Hyaluronan Receptors', 'Killer Cells, Natural', 'Lymphotoxin beta Receptor', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'NF-kappa B', "Peyer's Patches", 'Protein-Serine-Threonine Kinases', 'Proto-On... | 12,810,685 | [['B01.050'], ['D23.050.301.264.035.100', 'D23.050.301.264.894.080', 'D23.101.100.110.100', 'D23.101.100.894.080'], ['D23.050.301.264.035.100.500', 'D23.050.301.264.894.080.500', 'D23.101.100.110.100.500', 'D23.101.100.894.080.500'], ['G04.152'], ['A11.251'], ['B05.200'], ['A11.329.228'], ['D09.698.735.200.625', 'D12.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fabrication of conductive membrane in a polymeric electric field gradient focusing microdevice. | A novel approach to integrating a buffer ion-permeable membrane in a poly(glycidyl methacrylate-co-methyl methacrylate) micro electric field gradient focusing (muEFGF) device is described. A weir structure on which the membrane was positioned was fabricated between the separation channel and field gradient-generating c... | ['Electricity', 'Membranes, Artificial', 'Microwaves', 'Polymers'] | 16,808,478 | [['G01.358.500.249'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['D05.750', 'D25.720', 'J01.637.051.720']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Risk of cirrhosis and primary liver cancer in alpha 1-antitrypsin deficiency. | Previous reports have suggested an association between homozygous alpha 1-antitrypsin deficiency, cirrhosis, and primary liver cancer. To assess the risk of these complications we conducted a retrospective study based on 17 autopsied cases of alpha 1-antitrypsin deficiency identified during the period 1963 to 1982 in t... | ['Aged', 'Female', 'Humans', 'Liver Cirrhosis', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Retrospective Studies', 'Risk', 'Sweden', 'alpha 1-Antitrypsin Deficiency'] | 3,485,248 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.355.412'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Vaginal cervico-isthmic cerclage versus McDonald cerclage in women with a previous failure of prophylactic cerclage: A retrospective study. | AIM: Compare preterm births before 30 weeks of gestation in women with a previous failed McDonald cerclage that benefit from another McDonald cerclage (or simplified Shirodkar cerclage) or a vaginal cervico-isthmic cerclage.METHODS: Women with a cerclage performed at the end of the first trimester of a singleton pregna... | ['Adult', 'Cerclage, Cervical', 'Cervix Uteri', 'Female', 'Humans', 'Pregnancy', 'Premature Birth', 'Retreatment', 'Retrospective Studies', 'Treatment Outcome', 'Uterine Cervical Incompetence', 'Vagina'] | 28,697,395 | [['M01.060.116'], ['E04.520.100'], ['A05.360.319.679.256'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['C13.703.420.491.500'], ['E02.887'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Gastro-oesophageal reflux in pregnancy. Altered function of the barrier to reflux in asymptomatic women during early pregnancy. | The object of this study was to investigate the effect of early pregnancy on the competence of the barrier to gastro-oesophageal reflux (GOR). Oesophageal manometry and prolonged intra-oesophageal pH monitoring were carried out in 12 asymptomatic pregnant women and in 7 non-pregnant women. There was no significant diff... | ['Adult', 'Esophagogastric Junction', 'Female', 'Gastroesophageal Reflux', 'Humans', 'Hydrogen-Ion Concentration', 'Manometry', 'Pregnancy', 'Pregnancy Complications', 'Pregnancy Trimester, First', 'Pressure'] | 6,538,697 | [['M01.060.116'], ['A03.556.875.500.414', 'A03.556.875.875.330'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E05.559'], ['G08.686.784.769'], ['C13.703'], ['G08.686.707.408'], ['G01.374.715']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An open letter to my daughter. | The author writes a poignant "open" letter to her daughter about her experience with breast cancer, the family legacy of breast cancer, and the impact of learning there is a BRCA1 mutation in the family. | ['Adaptation, Psychological', 'Breast Neoplasms', 'Decision Making', 'Female', 'Genes, BRCA1', 'Genetic Predisposition to Disease', 'Genetic Testing', 'Humans', 'Mastectomy', 'Mother-Child Relations'] | 18,354,837 | [['F01.058'], ['C04.588.180', 'C17.800.090.500'], ['F02.463.785.373'], ['G05.360.340.024.340.375.249.100', 'G05.360.340.024.340.415.400.100'], ['C23.550.291.687.500', 'G05.380.355'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cortical auditory steady-state responses to low modulation rates. | This paper describes low-frequency auditory steady-state responses (ASSRs) to speech-weighted noise stimuli. The effect of modulation frequency was evaluated within the frequency range below 40 Hz. Furthermore, objective ASSR measures were related to speech understanding performance in normal-hearing and hearing-impair... | ['Acoustic Stimulation', 'Adult', 'Aged', 'Auditory Perception', 'Brain', 'Electroencephalography', 'Evoked Potentials', 'Hearing Disorders', 'Humans', 'Loudness Perception', 'Middle Aged', 'Pattern Recognition, Physiological', 'Psychoacoustics', 'Signal Detection, Psychological', 'Speech', 'Speech Perception', 'Time F... | 19,842,813 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.116'], ['M01.060.116.100'], ['F02.463.593.071', 'G07.888.125'], ['A08.186.211'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['C09.218.458', 'C10.597.751.418', 'C23.888.592.763.393'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
2-Arylindenes and 2-arylindenones: molecular structures and considerations in the binding orientation of unsymmetrical nonsteroidal ligands to the estrogen receptor. | We have studied how 2-arylindene systems, unsymmetrical nonsteroidal estrogens, orient themselves within the binding site of the estrogen receptor, relative to estradiol, by making a comprehensive comparison of the binding affinity of 16 analogues. These analogues are representatives of two major classes, those substit... | ['Animals', 'Cytosol', 'Estrogens', 'Female', 'Indenes', 'Molecular Structure', 'Rats', 'Receptors, Estrogen', 'Spectrometry, Fluorescence', 'Stereoisomerism', 'Structure-Activity Relationship', 'Thermodynamics', 'Uterus', 'X-Ray Diffraction'] | 2,769,689 | [['B01.050'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D27.505.696.399.472.277'], ['D02.455.426.559.847.486', 'D04.615.486'], ['G02.111.570', 'G02.466'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.826.750.350', 'D12.776.930.778.350'], ['E05.196.712.516.600.676', 'E05.196.867.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fumarate is the cause of the apparent ping-pong kinetics of dopamine beta-hydroxylase. | The kinetic mechanism of dopamine beta-hydroxylase (dopamine beta-monooxygenase EC 1.14.17.1) was studied either in the absence or the presence of the nonessential activator fumarate. In the absence of fumarate, intersecting initial velocity patterns were obtained, consistent with a sequential mechanism. In the presenc... | ['Adrenal Glands', 'Animals', 'Cattle', 'Dopamine beta-Hydroxylase', 'Fumarates', 'Kinetics', 'Tyramine'] | 4,084,318 | [['A06.300.071'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D08.811.682.690.708.292'], ['D02.241.081.337.302'], ['G01.374.661', 'G02.111.490'], ['D02.092.211.215.811']] | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mental action simulation synchronizes action-observation circuits across individuals. | A frontoparietal action-observation network (AON) has been proposed to support understanding others' actions and goals. We show that the AON "ticks together" in human subjects who are sharing a third person's feelings. During functional magnetic resonance imaging, 20 volunteers watched movies depicting boxing matches p... | ['Adult', 'Brain', 'Emotions', 'Female', 'Humans', 'Individuality', 'Magnetic Resonance Imaging', 'Male', 'Mental Processes', 'Middle Aged', 'Nerve Net', 'Observational Studies as Topic', 'Photic Stimulation', 'Young Adult'] | 24,431,433 | [['M01.060.116'], ['A08.186.211'], ['F01.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.488'], ['E01.370.350.825.500'], ['F02.463'], ['M01.060.116.630'], ['A08.511'], ['E05.318.372.250.500', 'N05.715.360.330.250.500', 'N06.850.520.450.250.500'], ['E05.723.729'], ['M01.060.116.815']] | ['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Role of renal interstitial pressure as a mediator of sodium retention during systemic blockade of nitric oxide. | The role of renal interstitial pressure was examined in mediating the sodium retention induced by blockade of nitric oxide synthesis. The effects of intravenous NG-nitro-L-arginine-methyl ester (L-NAME), a synthesis inhibitor, on renal hemodynamics, renal interstitial hydrostatic pressure, and sodium and lithium excret... | ['Animals', 'Arginine', 'Diuresis', 'Extracellular Space', 'Glomerular Filtration Rate', 'Hemodynamics', 'Hydrostatic Pressure', 'Kidney', 'Lithium', 'Male', 'NG-Nitroarginine Methyl Ester', 'Natriuresis', 'Nitric Oxide', 'Rats', 'Rats, Sprague-Dawley', 'Renal Circulation', 'Sodium'] | 8,505,106 | [['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['G08.852.179'], ['A10.082.500', 'A11.284.295'], ['E01.370.390.400.300', 'G08.852.357'], ['G09.330.380'], ['G01.374.715.352'], ['A05.810.453'], ['D01.268.549.450', 'D01.268.557.290', 'D01.552.528.480', 'D01.552.547.290'], ['D12.125.068.050.525', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glucose 6-phosphate dehydrogenase deficiency enhances germ cell apoptosis and causes defective embryogenesis in Caenorhabditis elegans. | Glucose 6-phosphate dehydrogenase (G6PD) deficiency, known as favism, is classically manifested by hemolytic anemia in human. More recently, it has been shown that mild G6PD deficiency moderately affects cardiac function, whereas severe G6PD deficiency leads to embryonic lethality in mice. How G6PD deficiency affects o... | ['Amino Acid Sequence', 'Animals', 'Apoptosis', 'Caenorhabditis elegans', 'Caenorhabditis elegans Proteins', 'DNA Damage', 'Embryonic Development', 'Germ Cells', 'Glucosephosphate Dehydrogenase', 'Glucosephosphate Dehydrogenase Deficiency', 'Humans', 'Hydrogen Peroxide', 'MAP Kinase Kinase 1', 'Mice', 'Mitogen-Activate... | 23,640,458 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G04.146.954.035'], ['B01.050.500.500.294.400.875.660.250.250'], ['D12.776.419.500'], ['G05.200'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['A05.360.490', 'A11.497'], ['D08.811.682.047.150.300'], ['C15.378.071.141.150.480', 'C16.320.070.480', 'C16.320.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Label-free and enzyme-free colorimetric detection of microRNA by catalyzed hairpin assembly coupled with hybridization chain reaction. | In this study, a simple, label-free, and enzyme-free colorimetric biosensor has been developed for amplified detection of let-7a microRNA (miRNA) on the basis of dual signal amplification strategy. The sensing system mainly consists of four unlabeled hairpin probes termed H1, H2, H3, and H4. Upon sensing of the target ... | ['Benzothiazoles', 'Biosensing Techniques', 'Colorimetry', 'Coloring Agents', 'DNA, Catalytic', 'G-Quadruplexes', 'Humans', 'Hydrogen Peroxide', 'Limit of Detection', 'Lung', 'MicroRNAs', 'Nucleic Acid Hybridization', 'Sulfonic Acids'] | 26,985,582 | [['D03.383.129.708.089', 'D03.633.100.185'], ['E05.601.043'], ['E05.196.922.250'], ['D27.720.233'], ['D08.811.165', 'D08.811.913.696.445.735.265', 'D13.444.308.243'], ['G02.111.570.820.486.550', 'G05.360.580.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', '... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Entomological investigation following the resurgence of human visceral leishmaniasis in southern Algeria. | Visceral and cutaneous leishmaniasis are the main endemic vector born diseases in Algeria. In the Hoggar region (extreme south of the country) human visceral leishmaniasis (HVL) is known to be sporadic but during the last decade the number of cases has increased significantly. In 2010, a peak of HVL cases was registere... | ['Adolescent', 'Algeria', 'Animals', 'Child', 'Child, Preschool', 'Communicable Diseases, Emerging', 'Entomology', 'Female', 'Humans', 'Infant', 'Insect Vectors', 'Insecta', 'Leishmaniasis, Visceral', 'Male', 'Retrospective Studies', 'Young Adult'] | 23,920,502 | [['M01.060.057'], ['Z01.058.266.104'], ['B01.050'], ['M01.060.406'], ['M01.060.406.448'], ['C01.221.500', 'C23.550.291.531.750'], ['H01.158.273.943.409'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['B01.050.500.131.617'], ['C01.610.752.... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Generation of destabilized herpes simplex virus type 1 thymidine kinase as transcription reporter for PET reporter systems in molecular genetic imaging. | UNLABELLED: Herpes simplex virus type 1 thymidine kinase (HSV1-TK) is a widely used reporter for in vivo noninvasive monitoring of therapeutic gene expression, immune cell trafficking, and protein-protein interactions in various animal systems. However, the stability of HSV1-TK limits its application in studies that re... | ['Animals', 'Cell Line', 'Cycloheximide', 'Doxycycline', 'Enzyme Stability', 'Female', 'Genes, Reporter', 'Herpesvirus 1, Human', 'Humans', 'Mice', 'Mutation', 'Nuclear Localization Signals', 'Ornithine Decarboxylase', 'Positron-Emission Tomography', 'Proteasome Endopeptidase Complex', 'Thymidine Kinase', 'Transcriptio... | 18,077,523 | [['B01.050'], ['A11.251.210'], ['D03.383.621.808.240'], ['D02.455.426.559.847.562.900.200', 'D04.615.562.900.200'], ['E05.916.360', 'G02.111.700.500'], ['G05.360.340.024.340.435'], ['B04.280.382.100.750.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['G05.365.590'],... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anti-Respiratory Syncytial Virus Compounds from Two Endophytic Fungi Isolated from Nigerian Medicinal Plants. | Background: Respiratory syncytial virus (RSV) is known to cause severe respiratory infections particularly in infants younger than 2 years of age. The only approved drug, ribavirin, is expensive and is not likely to improve therapeutic outcome, thereby necessitating the search for safer and more potent alternatives fro... | ['Antiviral Agents', 'Cells, Cultured', 'Colletotrichum', 'Humans', 'Microbial Sensitivity Tests', 'Nigeria', 'Plants, Medicinal', 'Respiratory Syncytial Viruses', 'Xylariales'] | 27,463,031 | [['D27.505.954.122.388'], ['A11.251'], ['B01.300.381.235'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['Z01.058.290.190.565'], ['B01.650.560'], ['B04.820.480.937.600.670.600.750'], ['B01.300.107.950']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
KeaA, a Dictyostelium Kelch-domain protein that regulates the response to stress and development. | BACKGROUND: The protein kinase YakA is responsible for the growth arrest and induction of developmental processes that occur upon starvation of Dictyostelium cells. yakA- cells are aggregation deficient, have a faster cell cycle and are hypersensitive to oxidative and nitrosoative stress. With the aim of isolating memb... | ['Cell Cycle', 'Cyclic AMP', 'Cytoskeletal Proteins', 'Dictyostelium', 'Protozoan Proteins', 'Signal Transduction', 'Stress, Physiological'] | 20,670,432 | [['G04.144'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D12.776.220'], ['B01.046.550.200.300'], ['D12.776.820'], ['G02.111.820', 'G04.835'], ['G07.775']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of oral metronidazole on the endocrine milieu and sebum excretion rate. | As part of a study of the mechanism of metronidazole's efficacy in the treatment of acne and rosacea, its effects on the endocrine milieu and sebum excretion rate were assessed. Thirteen healthy males received oral metronidazole treatment (500 mg/day) for 4 weeks. Serum sex hormone levels were determined in all 13 subj... | ['Administration, Oral', 'Adult', 'Gonadal Steroid Hormones', 'Humans', 'Lipid Metabolism', 'Male', 'Metronidazole', 'Sebum', 'Skin'] | 1,293,188 | [['E02.319.267.100'], ['M01.060.116'], ['D06.472.334.851'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.458'], ['D02.640.672.500', 'D03.383.129.308.658.500'], ['A12.200.702'], ['A17.815']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The problem of aeration of the ear during closed techniques (author's transl)]. | One of the major problem in otology today is maintaining aerated middle space when there is malfunction of the eustachian tube. The "closed technical" preserved the anatomy of the external and middle ears, but unknown the persistent non function of the eustachian tube. Also, in cholesteatoma a permanent aerating tube i... | ['Adult', 'Ear', 'Humans', 'Male', 'Ventilation'] | 7,469,279 | [['M01.060.116'], ['A01.456.313', 'A09.246'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.230.150.520']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Activity and polymorphisms of butyrylcholinesterase in a Polish population. | Butyrylcholinesterase (BChE) activity assay and inhibitor phenotyping can help to identify individuals at risk of prolonged paralysis following the administration of neuromuscular blocking agents, like succinylcholine, pesticides and nerve agents. In this study, the activity of BChE and its sensitivity to inhibition by... | ["3' Untranslated Regions", "5' Untranslated Regions", 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Butyrylcholinesterase', 'Child', 'Child, Preschool', 'Dibucaine', 'European Continental Ancestry Group', 'Exons', 'Female', 'Fluorides', 'Genotype', 'Humans', 'Introns', 'Male', 'Middle Aged', 'Nucleic Acid Confo... | 27,109,752 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['D13.444.735.544.875.885', 'D13.444.735.790.878.885', 'G05.360.340.024.220.880.885', 'G05.360.340.024.340.137.910.885'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.08... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Clinical and pathological characteristics of extramammary Paget's disease: report of 246 Chinese male patients. | Extramammary Paget's disease (EMPD) is a rare cutaneous neoplasm. The aim of this study was to elaborate the clinical and pathological features of Chinese EMPD male patients. The study comprised 246 patients with EMPD at our institute from January 1993 to December 2012. Scrotum was the most common initial site. The ave... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'China', 'Humans', 'Male', 'Middle Aged', 'Paget Disease, Extramammary', 'Prognosis', 'Prostate-Specific Antigen', 'Scrotum', 'Skin Neoplasms'] | 26,722,523 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.470.200.025.660', 'C04.557.470.615.660'], ['E01.789'], ['D08.811.277.656.300.760.442.750', 'D08.811.277.656.959.350.442.750', 'D12.776.866... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Factors affecting C3 in intestinal schistosomiasis. | Complement component C3 was investigated in sera of a group of schistosomal patients free from obvious nephritis. C3 was studied in relation to S. mansoni egg count, presence of HBsAg, and liver functions. C3 level was low in schistosomal patients than normal individuals. Levels were low in both HBsAg --ve and HBsAG +v... | ['Adolescent', 'Adult', 'Blood Proteins', 'Child', 'Complement C3', 'Hepatitis B Surface Antigens', 'Humans', 'Middle Aged', 'Schistosomiasis mansoni'] | 8,308,353 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124'], ['M01.060.406'], ['D12.776.124.050.140', 'D12.776.124.486.274.250'], ['D23.050.327.495.500.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C01.610.335.865.859.576', 'C01.920.922.576']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Drug-resistant tuberculosis--current dilemmas, unanswered questions, challenges, and priority needs. | Tuberculosis was declared a global emergency by the World Health Organization (WHO) in 1993. Following the declaration and the promotion in 1995 of directly observed treatment short course (DOTS), a cost-effective strategy to contain the tuberculosis epidemic, nearly 7 million lives have been saved compared with the pr... | ['Adult', 'Africa', 'Antitubercular Agents', 'Child', 'Communicable Disease Control', 'Directly Observed Therapy', 'Drug Administration Schedule', 'Drug Resistance, Multiple, Bacterial', 'Endemic Diseases', 'Global Health', 'Health Policy', 'Humans', 'Mycobacterium tuberculosis', 'Patient Rights', 'Time Factors', 'Tube... | 22,476,720 | [['M01.060.116'], ['Z01.058'], ['D27.505.954.122.085.255'], ['M01.060.406'], ['N06.850.780.200'], ['F01.100.150.750.500.600.500.500', 'F01.145.488.887.500.600.500.500', 'N05.300.150.800.500.600.500.500'], ['E02.319.283'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ... | ['Named Groups [M]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]... | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Enhanced contraceptive response by co-immunization of DNA and protein vaccines encoding the mouse zona pellucida 3 with minimal oophoritis in mouse ovary. | Zona pellucida 3 (ZP3) acts as the primary sperm receptor, induces autoantibody that can prevent oocyte fertilization and has been proposed as a vaccine candidate for contraception in humans. Due to the elicited autoreactive T cell inflammation that causes ovarian destruction, ZP3-based vaccine with removed T epitopes ... | ['Animals', 'Base Sequence', 'Contraception', 'DNA Primers', 'Female', 'Mice', 'Mice, Inbred C57BL', 'Ovary', 'Vaccines, DNA', 'Zona Pellucida'] | 17,957,814 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E02.875.194'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['A05.360.319.114.630', 'A05.360.576.497'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Immunohistochemical localization of glutathione S-transferase alpha and pi in human esophageal squamous epithelium, Barrett's epithelium and carcinoma. | High tissue levels of glutathione S-transferases (GSTs), a family of detoxification enzymes, are inversely correlated with cancer risk in the human gastrointestinal tract. Patients with Barrett's esophagus, wherein squamous epithelium is replaced by columnar epithelium, have an increased risk for developing esophageal ... | ['Adenocarcinoma', 'Adult', 'Aged', 'Barrett Esophagus', 'Carcinoma, Squamous Cell', 'Epithelium', 'Esophageal Neoplasms', 'Female', 'Glutathione S-Transferase pi', 'Glutathione Transferase', 'Humans', 'Immunohistochemistry', 'Isoenzymes', 'Male', 'Middle Aged', 'Precancerous Conditions'] | 10,391,093 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['C04.834.154', 'C06.405.117.102'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['A10.272'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['D08.811.913.225.500.500'], ['D08.811.913.225.500'], ['B0... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Immunofluorescent reactions with microfilariae: 1. Diagnostic evaluation. | Microfilariae have been evaluated as antigen for the indirect immunofluorescent test in the diagnosis of filariasis. Sonicated, unlike whole, microfilariae present no problems in handling on a slide. The cytoplasmic antigen that is exposed by sonication, unlike the sheath or cuticular antigen, reacts with filariasis se... | ['Antigens', 'Brugia', 'Complement Fixation Tests', 'Dirofilaria immitis', 'Filariasis', 'Filarioidea', 'Fluorescent Antibody Technique', 'Humans', 'Microfilariae', 'Species Specificity'] | 339,419 | [['D23.050'], ['B01.050.500.500.294.400.937.463.088'], ['E01.370.225.812.735.150', 'E05.200.812.735.150', 'E05.478.594.760.150'], ['B01.050.500.500.294.400.937.463.230.300'], ['C01.610.335.508.700.750.361'], ['B01.050.500.500.294.400.937.463'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The learning curve associated with the epidural technique using the Episure™ AutoDetect™ versus conventional glass syringe: an open-label, randomized, controlled, crossover trial of experienced anesthesiologists in obstetric patients. | BACKGROUND: The Episure™ AutoDetect™ (spring-loaded) syringe has been observed to successfully identify the epidural space in 2 pilot studies. In this study we evaluated the impact of the spring-loaded syringe on the establishment of successful epidural labor analgesia (primary outcome), elapsed time for catheter place... | ['Adult', 'Anesthesia, Epidural', 'Anesthesiology', 'Catheterization', 'Clinical Competence', 'Confidence Intervals', 'Cross-Over Studies', 'Double-Blind Method', 'Female', 'Humans', 'Learning Curve', 'Pain Measurement', 'Pregnancy', 'Syringes'] | 23,223,103 | [['M01.060.116'], ['E03.155.086.131'], ['H02.403.066'], ['E02.148', 'E05.157'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Comparison of three modes of measuring stress, coping, and humor in school-age children. | Computer-assisted administration of surveys is gaining popularity among many researchers, but the equivalence of this method to more traditional approaches such as using paper and pencil has not been determined for many commonly used questionnaires, particularly among school-age children. This study examined systematic... | ['Adaptation, Psychological', 'Attitude to Health', 'Child', 'Cultural Diversity', 'Data Collection', 'Electronic Data Processing', 'Factor Analysis, Statistical', 'Female', 'Humans', 'Male', 'Multivariate Analysis', 'Nursing Assessment', 'Nursing Evaluation Research', 'Nursing Methodology Research', 'Psychology, Child... | 17,086,782 | [['F01.058'], ['F01.100.150', 'N05.300.150'], ['M01.060.406'], ['I01.076.201.450.350', 'I01.880.853.100.450'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['L01.224.085'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Humanities... | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Treatment of metastatic spinal cord compression: an unsettled issue. | Spinal cord compression as an oncological complication is presented. The benefits of radiation therapy, as either an alternative or an addition to surgery, are discussed, as well as the most frequently affected sites of cord compression. | ['Combined Modality Therapy', 'Humans', 'Spinal Cord Compression', 'Spinal Neoplasms'] | 6,716,506 | [['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.854.761', 'C26.819.678'], ['C04.588.149.828', 'C05.116.231.828', 'C05.116.900.801']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A novel eIF4E-interacting protein that forms non-canonical translation initiation complexes. | Translation is a fundamental step in gene expression that regulates multiple developmental and stress responses. One key step of translation initiation is the association between eIF4E and eIF4G. This process is regulated in different eukaryotes by proteins that bind to eIF4E; however, evidence of eIF4E-interacting pro... | ['Arabidopsis', 'Arabidopsis Proteins', 'Binding Sites', 'Eukaryotic Initiation Factor-4E', 'Eukaryotic Initiation Factor-4G', 'Eukaryotic Initiation Factors', 'Protein Binding', 'Protein Biosynthesis', 'Protein Domains', 'RNA, Messenger'] | 31,819,221 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G02.111.570.120'], ['D12.776.157.725.750.374', 'D12.776.835.725.868.500.750'], ['D12.776.835.725.868.500.875'], ['D12.776.835.725.868'], ['G02.111.679', 'G03.808'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['G02.111.570.820.709.275.750', 'G02.11... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Proton accumulation and ATPase activity in Golgi apparatus-enriched vesicles from rat liver. | We have studied the mechanism by which liver Golgi apparatus maintains the acidity of its contents, using a subcellular fraction from rat liver highly enriched in Golgi marker enzymes. Proton accumulation (measured by quenching of acridine-orange fluorescence) and anion-dependent ATPase were characterized and compared.... | ['Adenosine Triphosphatases', 'Animals', 'Chlorides', 'Golgi Apparatus', 'Ions', 'Liver', 'Male', 'Nitrates', 'Nucleotides', 'Protons', 'Rats', 'Rats, Inbred Strains'] | 1,847,895 | [['D08.811.277.040.025'], ['B01.050'], ['D01.210.450.150', 'D01.248.497.158.215'], ['A11.284.430.214.190.875.336'], ['D01.248.497'], ['A03.620'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['D09.408.620', 'D13.695'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['B01... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Blood transfusion and renal allograft survival. | Thirty-two first renal transplantations with cadaveric allografts were reviewed to see how many of the recipients had received blood transfusions preoperatively. There was a significant difference in transplant survival between patients who had and patients who had not received blood transfusion before transplantation;... | ['Blood Transfusion', 'Cadaver', 'Female', 'Graft Survival', 'Humans', 'Kidney Transplantation', 'Male', 'Transplantation, Homologous'] | 339,996 | [['E02.095.135'], ['C23.550.260.224'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['E04.936.864']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cerebrovascular pattern improved by ozone autohemotherapy: an entropy-based study on multiple sclerosis patients. | Ozone major autohemotherapy is effective in reducing the symptoms of multiple sclerosis (MS) patients, but its effects on brain are still not clear. In this work, we have monitored the changes in the cerebrovascular pattern of MS patients and normal subjects during major ozone autohemotherapy by using near-infrared spe... | ['Adult', 'Blood Flow Velocity', 'Brain', 'Brain Mapping', 'Cerebrovascular Circulation', 'Entropy', 'Female', 'Humans', 'Male', 'Multiple Sclerosis', 'Oxygen Consumption', 'Ozone', 'Spectroscopy, Near-Infrared', 'Thermodynamics', 'Treatment Outcome'] | 27,734,309 | [['M01.060.116'], ['E01.370.370.130', 'G09.330.380.630.080'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['G09.330.100.159'], ['G01.906.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['G03.680'], ['D... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Peptide inhibitors of MK2 show promise for inhibition of abdominal adhesions. | BACKGROUND: Abdominal adhesions are a common side effect of surgical procedures with complications including infertility, chronic pain, and bowel obstruction, which may lead to the need for surgical lyses of the adhesions. Mitogen-activated protein kinase-activated protein kinase 2 (MK2) has been implicated in several ... | ['Abdomen', 'Animals', 'Cell-Penetrating Peptides', 'Cells, Cultured', 'Dose-Response Relationship, Drug', 'Epithelial Cells', 'Humans', 'Hydroxyproline', 'Inhibitory Concentration 50', 'Interleukin-1beta', 'Interleukin-6', 'Intracellular Signaling Peptides and Proteins', 'Models, Animal', 'Protein Kinase Inhibitors', ... | 21,492,875 | [['A01.923.047'], ['B01.050'], ['D12.644.098'], ['A11.251'], ['G07.690.773.875', 'G07.690.936.500'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.125.072.401.623.478'], ['E05.940.350', 'G07.690.936.563'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500.400.600', 'D12.776.467.374.465.010.600'... | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Maternal depression during pregnancy and offspring depression in adulthood: role of child maltreatment. | BACKGROUND: Studies have shown that maternal depression during pregnancy predicts offspring depression in adolescence. Child maltreatment is also a risk factor for depression.AIMS: To investigate (a) whether there is an association between offspring exposure to maternal depression in pregnancy and depression in early a... | ['Adolescent', 'Adult', 'Adult Survivors of Child Abuse', 'Child', 'Child Abuse', 'Child, Preschool', 'Depression, Postpartum', 'Depressive Disorder', 'Female', 'Humans', 'Longitudinal Studies', 'Pregnancy', 'Pregnancy Complications', 'Prenatal Exposure Delayed Effects', 'Prospective Studies', 'Young Adult'] | 26,045,352 | [['M01.060.057'], ['M01.060.116'], ['M01.135.500', 'M01.860.300.500'], ['M01.060.406'], ['I01.198.240.856.350.250', 'I01.880.735.900.350.250'], ['M01.060.406.448'], ['C13.703.844.253', 'F03.600.300.350'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Pulmonary emphysema and hepatic involvement by alpha-1 antitrypsin deficiency in two adults with a PiZ phenotype (author's transl)]. | Two unreleated adult males were found to be suffering from an association of pan-lobular severe emphysema and hepatomegally of unknown origin which led to the discovery of a marked deficit in alpha-1 antitrypsin (A1-AT) in relation to a PiZ phenotype. Liver biopsy revealed cirrhosis with portal fibrosis in one case and... | ['Adult', 'Hepatomegaly', 'Humans', 'Liver', 'Male', 'Middle Aged', 'Pedigree', 'Phenotype', 'Protease Inhibitors', 'Pulmonary Emphysema', 'alpha 1-Antitrypsin Deficiency'] | 307,225 | [['M01.060.116'], ['C06.552.416', 'C23.300.775.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['M01.060.116.630'], ['E05.393.673'], ['G05.695'], ['D27.505.519.389.745'], ['C08.381.495.389.750'], ['C06.552.074', 'C08.381.112', 'C16.320.060', 'C23.550.325.500.500']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A novel pyrolytic carbon implant for hallux rigidus: a cadaveric study. | BACKGROUND: The aim of this cadaveric study was to assess the technical feasibility of inserting a novel interpositional pyrolytic carbon coated implant in the first MTP joint, determine the best surgical procedure for the implantation, and evaluate the dynamic behavior of the joint after surgery.METHODS: The marble im... | ['Cadaver', 'Carbon', 'Hallux Rigidus', 'Humans', 'Prostheses and Implants', 'Prosthesis Design'] | 21,783,081 | [['C23.550.260.224'], ['D01.268.150'], ['C05.330.488.310', 'C05.550.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695'], ['E05.320.550', 'E07.695.680']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Novel Approach for Measuring and Communicating State Health Trends Over Time. | OBJECTIVE: To develop a method to assess long-term and recent progress for leading health indicators in Wisconsin.METHODS: Data from state and national sources were compiled. Baseline (10-year) trends for 20 health indicators were measured and compared to the Healthy People 2020 improvement standard of 1% per year. Add... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Continental Population Groups', 'Female', 'Health Status Disparities', 'Health Status Indicators', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Socioeconomic Factors', 'Wisconsin'] | 26,854,311 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['M01.686.508'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Rotavirus disrupts calcium homeostasis by NSP4 viroporin activity. | Many viruses alter intracellular calcium homeostasis. The rotavirus nonstructural protein 4 (NSP4), an endoplasmic reticulum (ER) transmembrane glycoprotein, increases intracellular levels of cytoplasmic Ca(2+) ([Ca(2+)]cyto) through a phospholipase C-independent pathway, which is required for virus replication and mor... | ['Animals', 'Calcium', 'Cell Line', 'Cytoplasm', 'DNA Mutational Analysis', 'Endoplasmic Reticulum', 'Glycoproteins', 'Homeostasis', 'Humans', 'Models, Biological', 'Models, Chemical', 'Porins', 'Protein Structure, Tertiary', 'Rotavirus', 'Toxins, Biological', 'Viral Nonstructural Proteins', 'Virulence Factors'] | 21,151,776 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251.210'], ['A11.284.430.214'], ['E05.393.760.700.300'], ['A11.284.430.214.190.875.248'], ['D09.400.430', 'D12.776.395'], ['G07.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['E05.599.495'], ['D12.776.157.530.400.500',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessing the Relationship of Mammographic Breast Density and Proliferative Breast Disease. | Increased breast density and a history of benign breast biopsy are both considered risk factors for developing breast cancer. Understanding the specifics of these risk factors and their relationship to each other can lead to a better understanding of a patient's propensity for breast cancer development and improved sur... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biopsy', 'Breast Density', 'Breast Diseases', 'Calcinosis', 'Female', 'Humans', 'Mammography', 'Middle Aged', 'Postmenopause', 'Premenopause'] | 27,261,096 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.370.600.115.275', 'G07.100.138'], ['C17.800.090'], ['C18.452.174.130'], ['B01.050.150.900.649.313.988.400.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cloning, expression, and localization of a new member of a Paracentrotus lividus cell surface multigene family. | We have isolated and characterized a cDNA clone corresponding to a new member of bep (butanol, extracted, proteins) Paracentrotus lividus multigene family coding for cell surface proteins. The cDNA, called bep3, encodes a 370 amino acid protein and shares the same structural organization in the coding region with other... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Blotting, Southern', 'Cloning, Molecular', 'DNA', 'Gene Expression', 'Membrane Proteins', 'Molecular Sequence Data', 'Multigene Family', 'RNA, Messenger', 'Sea Urchins'] | 8,722,690 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['E05.393.220'], ['D13.444.308'], ['G05.297'], ['D12.776.543'], ['L01.453.245.667'], ['G05.360.340.024.340.645'], ['D13.444.735.544'], ['B01.050.500... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Fast state-space methods for inferring dendritic synaptic connectivity. | We present fast methods for filtering voltage measurements and performing optimal inference of the location and strength of synaptic connections in large dendritic trees. Given noisy, subsampled voltage observations we develop fast l1-penalized regression methods for Kalman state-space models of the neuron voltage dyna... | ['Algorithms', 'Computer Simulation', 'Dendrites', 'Models, Neurological', 'Neurons', 'Synapses'] | 24,077,932 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['E05.599.395.642'], ['A08.675', 'A11.671'], ['A08.850', 'A11.284.149.165.420.780']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Induction of ornithine decarboxylase activity in rat glandular stomach mucosa by bile acids. | A single oral instillation of 1.5 g/kg body weight of sodium taurocholate resulted in a rapid, transient stimulation of ornithine decarboxylase activity in rat glandular stomach mucosa, reaching a peak (10 times the control value) 4 to 6 hr after sodium taurocholate treatment and returning to the control level within 4... | ['Animals', 'Bile Acids and Salts', 'Dose-Response Relationship, Drug', 'Gastric Mucosa', 'Male', 'Ornithine Decarboxylase', 'Rats', 'Rats, Inbred Strains', 'Time Factors'] | 3,093,422 | [['B01.050'], ['D04.210.500.105'], ['G07.690.773.875', 'G07.690.936.500'], ['A03.556.875.875.440', 'A10.615.550.291'], ['D08.811.520.224.125.425'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['G01.910.857']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A review of domestic dogs' (Canis familiaris) human-like behaviors: or why behavior analysts should stop worrying and love their dogs. | Dogs likely were the first animals to be domesticated and as such have shared a common environment with humans for over ten thousand years. Only recently, however, has this species' behavior been subject to scientific scrutiny. Most of this work has been inspired by research in human cognitive psychology and suggests t... | ['Animals', 'Behavior, Animal', 'Cognition', 'Cues', 'Dogs', 'Human-Animal Bond', 'Humans', 'Love'] | 18,422,021 | [['B01.050'], ['F01.145.113'], ['F02.463.188'], ['F02.463.425.234'], ['B01.050.150.900.649.313.750.250.216.200'], ['F01.145.496.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.470.734']] | ['Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mass media messages and reproductive behaviour in Nigeria. | This paper examines the effects of exposure to mass media messages promoting family planning on the reproductive behaviour of married women in Nigeria using cross-sectional data. Longitudinal data are also used to ensure that exposure to media messages pre-dates the indicators of reproductive behaviour. Cross-sectional... | ['Adolescent', 'Adult', 'Cross-Sectional Studies', 'Developing Countries', 'Family Characteristics', 'Family Planning Services', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Infant, Newborn', 'Longitudinal Studies', 'Mass Media', 'Middle Aged', 'Nigeria', 'Pregnancy', 'Socioeconomic Factors'] | 8,935,878 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.615.500.300'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['N02.421.143.401', 'N02.421.800.249'], ['F01.100.150.500', 'N05.300.150.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
I-motif DNA structures are formed in the nuclei of human cells. | Human genome function is underpinned by the primary storage of genetic information in canonical B-form DNA, with a second layer of DNA structure providing regulatory control. I-motif structures are thought to form in cytosine-rich regions of the genome and to have regulatory functions; however, in vivo evidence for the... | ['Cell Cycle', 'Cell Nucleus', 'DNA', 'Genome, Human', 'HeLa Cells', 'Humans', 'Hydrogen-Ion Concentration', 'Immunoglobulin Fragments', 'MCF-7 Cells', 'Nucleic Acid Conformation', 'Promoter Regions, Genetic', 'Telomere'] | 29,686,376 | [['G04.144'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D13.444.308'], ['G05.360.340.350'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['D12.644.541.500', 'D12.776.124.486.485.680', 'D12.776.124.790.651.680', 'D12.776.377.715.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
geneAttribution: trait agnostic identification of candidate genes associated with noncoding variation. | Motivation: We have developed geneAttribution, an R package that assigns candidate causal gene(s) to a risk variant identified by a genetic association study such as a GWAS. The method combines user-supplied functional annotation such as expression quantitative trait loci (eQTL) or Hi-C genome conformation data and rep... | ['Genetic Association Studies', 'Genome, Human', 'Humans', 'Phenotype', 'Polymorphism, Genetic', 'Promoter Regions, Genetic', 'Quantitative Trait Loci', 'Software'] | 28,035,029 | [['E05.393.385'], ['G05.360.340.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.695'], ['G05.365.795'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['G05.360.340.024.380.937'], ['L01.224.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Alterations in neuronal survival and glial reactions after axotomy by ceftriaxone and minocycline in the mouse hypoglossal nucleus. | Some antibiotics are suggested to exert neuroprotective effects via regulation of glial responses. Attenuation of microglial activation by minocycline prevents neuronal death in a variety of experimental models for neurological diseases, such as cerebral ischemia, Parkinson's and Huntington's disease. Ceftriaxone delay... | ['Animals', 'Astrocytes', 'Axotomy', 'Ceftriaxone', 'Cell Survival', 'Disease Models, Animal', 'Drug Evaluation, Preclinical', 'Drug Interactions', 'Glial Fibrillary Acidic Protein', 'Hypoglossal Nerve Injuries', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Microglia', 'Minocycline', 'Motor Neuron Disease', 'Nerve Tissue Pro... | 21,970,974 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['E04.525.210.158'], ['D02.065.589.099.249.190.190.155', 'D02.886.665.074.190.190.155', 'D03.633.100.300.249.190.190.155'], ['G04.346'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.290.750', 'E05.337.550'], ['G07.690.773.968'], ['D05.750.078.593.400', 'D12.776.220.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Pentratricopeptide Repeat Protein Pigment-Defective Mutant2 is Involved in the Regulation of Chloroplast Development and Chloroplast Gene Expression in Arabidopsis. | The development of functional chloroplasts, which is assisted by a series of nuclear-encoded auxiliary protein factors, is essential for plant autotrophic growth and development. To understand the molecular mechanisms underlying chloroplast development, we isolated and characterized a pigment-defective mutant, pdm2, an... | ['Arabidopsis', 'Arabidopsis Proteins', 'Chloroplasts', 'Gene Expression Regulation, Plant', 'Gene Knockdown Techniques', 'Genes, Chloroplast', 'Mutation', 'Plants, Genetically Modified', 'Plastids', 'RNA Editing', 'Seeds'] | 28,158,776 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['A11.284.430.214.190.875.700.140'], ['G05.308.375'], ['E05.393.335.500'], ['G05.360.340.024.340.225', 'G05.420.275.249'], ['G05.365.590'], ['B01.650.520', 'B05.620.600'], ['A11.284.430.214.190.875.700'], ['G02.111.760.250', 'G03.839.250', 'G05.308.700.250'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Histochemical and biochemical research on the pallial gland of Lithophaga (Lithodomus) lithophaga L. | Histomorphological staining demonstrated 2 types of cells in the pallial gland of the mantle of Lithodomus lithophaga: gland cells containing glycolipoprotein and interstitial cells, containing lipid droplets. Biochemical analysis aiming at separate and evaluate lipidic and peptidic components were carried out by lipid... | ['Amino Acids', 'Animals', 'Bivalvia', 'Carbohydrates', 'Glycogen', 'Glycosaminoglycans', 'Histocytochemistry', 'Lipids', 'Proteins'] | 132,075 | [['D12.125'], ['B01.050'], ['B01.050.500.644.080'], ['D09'], ['D05.750.078.562.388', 'D09.698.365.388'], ['D09.698.373'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['D10'], ['D12.776']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Role of angiotensin II receptor type 2 in predicting biochemical recurrence in the treatment of prostate cancer]. | AIM: To identify markers for predicting aggressive forms of prostate cancer.MATERIALS AND METHODS: The study retrospectively evaluated expression of angiotensin II type 2 receptors (AT2-R) in prostate needle biopsy tissue from patients with and without biochemical recurrence after combined hormone and radiation therapy... | ['Aged', 'Biomarkers, Tumor', 'Humans', 'Male', 'Neoplasm Recurrence, Local', 'Prostate', 'Prostatic Neoplasms', 'Receptor, Angiotensin, Type 2'] | 28,248,050 | [['M01.060.116.100'], ['D23.101.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.655', 'C23.550.727.655'], ['A05.360.444.575', 'A10.336.707'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['D12.776.543.750.695.047.687', 'D12.776.543.750.750.130.875']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Incorporating Group Medical Visits into Primary Healthcare: Are There Benefits? | OBJECTIVE: Group medical visits (GMVs) have been touted as an innovation to effectively and efficiently provide primary healthcare (PHC) services. The purpose of this paper is to report whether GMVs have tangible benefits for providers and patients.METHODS: This descriptive study included in-depth interviews with patie... | ['Adult', 'Aged', 'Aged, 80 and over', 'Attitude to Health', 'British Columbia', 'Canada', 'Chronic Disease', 'Delivery of Health Care', 'Female', 'Group Processes', 'Health Personnel', 'Health Services, Indigenous', 'Humans', 'Indians, North American', 'Male', 'Middle Aged', 'Patient Satisfaction', 'Patient-Centered C... | 26,742,114 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.150', 'N05.300.150'], ['Z01.107.567.176.160'], ['Z01.107.567.176'], ['C23.550.291.500'], ['N04.590.374', 'N05.300'], ['F01.829.316'], ['M01.526.485', 'N02.360'], ['N02.421.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.150.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[A distinctive scheme of amino acid replacement was evolved for the generation of diversity, among hypervariable positions (author's transl)]. | The diversity of amino acid residues, at a same position when comparing several aligned polypeptide sequences, may be translated as follows. The way along which a given amino acid, A, is replaced--in average--by another amino acid, B, is characterized by a coefficient linked with the pair A-B. Thus, one given amino aci... | ['Amino Acid Sequence', 'Amino Acids', 'Genetic Variation', 'Immunoglobulin Heavy Chains', 'Immunoglobulin Light Chains', 'Statistics as Topic'] | 6,784,660 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125'], ['G05.365'], ['D12.776.124.486.485.705.500', 'D12.776.124.790.651.705.500', 'D12.776.377.715.548.705.500'], ['D12.776.124.486.485.705.750', 'D12.776.124.790.651.705.750', 'D12.776.377.715.548.705.750'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Flight variability in the woodwasp Sirex noctilio (Hymenoptera: Siricidae): an analysis of flight data using wavelets. | We describe flight variability in the woodwasp Sirex noctilio Fabricius, 1793 (Hymenoptera: Siricidae) by studying tethered females in a flight mill device and analyzing output data by a time series methodology. Twenty-eight wasps were flown during 24 h-long periods, under controlled temperature and lighting conditions... | ['Animals', 'Body Weight', 'Female', 'Flight, Animal', 'Wasps'] | 19,218,525 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G11.427.410.568.304', 'G11.427.410.698.416'], ['B01.050.500.131.617.720.500.500.875.900']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Successful treatment of cryptococcal meningitis with amphotericin B colloidal dispersion: report of four cases. | Four patients with cryptococcal meningitis were treated with amphotericin B colloidal dispersion because of nephrotoxicity from prior treatment with conventional amphotericin B. The limited experience presented here suggests that amphotericin B colloidal dispersion is efficacious for the treatment of cryptococcal menin... | ['AIDS-Related Opportunistic Infections', 'Amphotericin B', 'Antifungal Agents', 'Colloids', 'Diabetes Mellitus, Type 2', 'Heart Transplantation', 'Humans', 'Liver Diseases', 'Male', 'Meningitis, Cryptococcal', 'Middle Aged', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'Suspensions'] | 8,585,754 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['D02.540.576.500.500'], ['D27.505.954.122.136'], ['D20.280', 'D26.255.165'], ['C18.452.394.750.149', 'C19.246.300'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['B01.050.150.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[New method of diminishing cyst cavities]. | For diminishing the cyst cavity after cystectomia the following method is being suggested: The cyst sack is removed as usual after forming a trapezium-like muco-periostyle soft flat tissue by means of a vestibular bone opening. Foremost and furthest to the opening other openings are bored into the bone. Then "U" like s... | ['Cysts', 'Humans', 'Suture Techniques'] | 2,699,961 | [['C04.182', 'C23.300.306'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.987.775']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Intravaginal culture and embryo transfer. A new method for the fertilization of human oocytes]. | This technique was developed at the University Clinic of Port-Royal. It corresponds to the intravaginal culture of embryos and their transfer into the uterus. After ovocyte stimulation, most often by Clomid HMG, the follicles are aspirated under laparoscopic or sonographic control 34 to 36 hours after HCG. After being ... | ['Adult', 'Embryo Transfer', 'Female', 'Fertilization in Vitro', 'Humans', 'Infertility, Female', 'Pregnancy'] | 3,432,897 | [['M01.060.116'], ['E02.875.800.500', 'E05.820.800.500'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['G08.686.784.769']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Magnitude of sedentary behavior and associated factors among secondary school adolescents in Debre Berhan town, Ethiopia. | BACKGROUND: Sedentary life style is becoming increasingly common in this industrial age due to changes on the way people manufacture, transport and communicate. Sedentary lifestyle is associated with chronic diseases (diabetes, cardiovascular disease, and cancer), depression, obesity and premature mortality. The object... | ['Adolescent', 'Adolescent Behavior', 'Cross-Sectional Studies', 'Ethiopia', 'Female', 'Humans', 'Male', 'Risk Factors', 'Schools', 'Sedentary Behavior', 'Socioeconomic Factors', 'Students'] | 31,959,154 | [['M01.060.057'], ['F01.145.022'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.058.290.120.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.72... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Anaesthetic management of congenital laryngeal web presenting with acute upper airway obstruction. | This is a case of failed intubation in a child of 15 months due to presence of laryngeal web. The airway was maintained by Cole Neonatal tube size 2 mm held at the available orifice of the glottis with maintenance of spontaneous respiration under general anesthesia till emergency tracheostomy was performed. | ['Acute Disease', 'Airway Obstruction', 'Anesthesia', 'Humans', 'Infant', 'Intubation, Intratracheal', 'Larynx'] | 20,803,862 | [['C23.550.291.125'], ['C08.618.846.185'], ['E03.155'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['A04.329']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Autopsy findings in 42 consecutive patients with idiopathic pulmonary fibrosis. | Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive lung disease that commonly results in respiratory failure and death. However, the cause of death in these patients has not previously been fully defined. The current study reviews the clinical records and pathological findings of 42 consecutive patients ... | ['Aged', 'Aged, 80 and over', 'Autopsy', 'Cause of Death', 'Cohort Studies', 'Female', 'Humans', 'Lung', 'Male', 'Middle Aged', 'Minnesota', 'Pulmonary Fibrosis', 'Retrospective Studies'] | 18,256,070 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Geographicals [Z]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[The antisera avidity]. | In a LN-equivalence point titration system the modulation of immune complex formation of high avide antisera by specific and unspecific factors is measurable. Protamine-Cl is a potent enhancer of complex formation. | ['Animals', 'Antibody Affinity', 'Antigen-Antibody Complex', 'Humans', 'Immune Sera', 'Lasers', 'Nephelometry and Turbidimetry', 'Polyethylene Glycols', 'Protamines', 'Rabbits'] | 6,534,843 | [['B01.050'], ['G12.040', 'G12.122.125'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.114.573', 'D... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Physiological responses of coccolithophores to abrupt exposure of naturally low pH deep seawater. | Upwelling is the process by which deep, cold, relatively high-CO2, nutrient-rich seawater rises to the sunlit surface of the ocean. This seasonal process has fueled geoengineering initiatives to fertilize the surface ocean with deep seawater to enhance productivity and thus promote the drawdown of CO2. Coccolithophores... | ['Adaptation, Physiological', 'Carbon Dioxide', 'Haptophyta', 'Hydrogen-Ion Concentration', 'Seawater'] | 28,750,008 | [['G07.025', 'G16.012.500'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['B01.400'], ['G02.300'], ['G16.500.275.725.500']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diversity of bovine rumen methanogens In vitro in the presence of condensed tannins, as determined by sequence analysis of 16S rRNA gene library. | Molecular diversity of rumen archaeal populations from bovine rumen fluid incubated with or without condensed tannins was investigated using 16S rRNA gene libraries. The predominant order of rumen archaea in the 16S rRNA gene libraries of the control and condensed tannins treatment was found to belong to a novel group ... | ['Animals', 'Archaea', 'Cattle', 'DNA, Archaeal', 'DNA, Ribosomal', 'Gene Library', 'Genes, rRNA', 'Genetic Variation', 'Methane', 'Methanobacteriales', 'Methanomicrobiales', 'Methanosarcinales', 'Molecular Sequence Data', 'Proanthocyanidins', 'RNA, Ribosomal, 16S', 'Rumen', 'Sequence Analysis, DNA'] | 21,717,338 | [['B01.050'], ['B02'], ['B01.050.150.900.649.313.500.380.271'], ['D13.444.308.180'], ['D13.444.308.475'], ['G05.360.325'], ['G05.360.340.024.340.645.750'], ['G05.365'], ['D02.455.326.146.571'], ['B02.200.492'], ['B02.200.705'], ['B02.200.765'], ['L01.453.245.667'], ['D03.383.663.283.266.450.700', 'D03.633.100.150.266.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Biometric Identification from Human Aesthetic Preferences. | In recent years, human-machine interactions encompass many avenues of life, ranging from personal communications to professional activities. This trend has allowed for person identification based on behavior rather than physical traits to emerge as a growing research domain, which spans areas such as online education, ... | ['Biometric Identification', 'Esthetics', 'Gene Expression Regulation', 'Humans', 'Image Processing, Computer-Assisted', 'Models, Theoretical', 'Support Vector Machine'] | 32,093,028 | [['E05.318.740.225.500', 'N04.452.910.099'], ['F02.463.785.477', 'K01.752.210'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E05.599'], ['G17.035.250.500.500.500', 'L01.224.050.375.530.500.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Java Web Start based software for automated quantitative nuclear analysis of prostate cancer and benign prostate hyperplasia. | BACKGROUND: Androgen acts via androgen receptor (AR) and accurate measurement of the levels of AR protein expression is critical for prostate research. The expression of AR in paired specimens of benign prostate and prostate cancer from 20 African and 20 Caucasian Americans was compared to demonstrate an application of... | ['Algorithms', 'Artificial Intelligence', 'Biomarkers, Tumor', 'Cell Nucleus', 'Humans', 'Image Interpretation, Computer-Assisted', 'Male', 'Programming Languages', 'Prostatic Hyperplasia', 'Prostatic Neoplasms', 'Receptors, Androgen', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Software'] | 15,888,205 | [['G17.035', 'L01.224.050'], ['G17.035.250', 'L01.224.050.375'], ['D23.101.140'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['L01.224.900.780'], ['C12.294.565.500'], ['C04.588.945.440.770', 'C12... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Reducing dietary salt intake: an important public health strategy in Switzerland]. | Current dietary salt (sodium chloride) intake largely exceeds physiological needs (about 1.5 g salt per day, or 550 mg sodium per day) in most countries (> 8 g salt per day). The main sources of dietar salt intake are breads, cheeses, products derived from meat and ready-to-eat meals. On average, a high-salt diet is as... | ['Adult', 'Aged', 'Cardiovascular Diseases', 'Food', 'Humans', 'Hypertension', 'Middle Aged', 'Preventive Medicine', 'Public Health', 'Social Medicine', 'Sodium Chloride, Dietary', 'Surveys and Questionnaires', 'Switzerland'] | 20,373,695 | [['M01.060.116'], ['M01.060.116.100'], ['C14'], ['G07.203.300', 'J02.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['H02.403.720.750'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['H02.403.800'], ['D01.857.650.705', 'D01.857.875.705'], ['E05.318.308.980', 'N05.715.360.300... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 |
A possible relation between pressure loading and thickened leaflets of the aortic valve: a model simulation. | A much smaller percentage of thickened leaflets of the aortic valve have been found in the right or left coronary leaflet than in the noncoronary leaflet. This study investigated the pressure loading transferring to the leaflets of the aortic valve and their effects on the valvular thickening. A simple ascending aorta ... | ['Aorta', 'Aortic Valve', 'Blood Pressure', 'Coronary Vessels', 'Diastole', 'Humans', 'Hypertrophy', 'Models, Cardiovascular', 'Pulsatile Flow', 'Sinus of Valsalva'] | 7,858,777 | [['A07.015.114.056'], ['A07.541.510.110'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07.015.114.269', 'A07.015.908.194'], ['G09.330.580.295', 'G11.427.494.554.250', 'G11.427.494.570.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.775'], ['E05.599.395.161'], ['G01.482.620', 'G09.330.380.630.555'],... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hydrocephalus. | In treating patients with hydrocephalus, cerebral ventricular shunts and their complications are often encountered by the primary care provider. Caring for these patients can provoke anxiety and doubt in those who have had little exposure in dealing with shunts. Becoming familiar with the clinical findings, etiology, a... | ['Cerebrospinal Fluid Shunts', 'Humans', 'Hydrocephalus'] | 11,892,883 | [['E04.035.188', 'E04.525.170'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.602']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The nuclear oestrogen receptor in the female rat. Effects of oestradiol administration during the oestrous cycle on the uterus and contrasting effects of progesterone on the uterus and hypothalamus. | Oestradiol administration to immature or ovariectomized rats has been reported to increase the uterine content of long-term nuclear oestrogen receptors. However, in the intact adult female rat, oestradiol administration did not increase the concentration of long-term nuclear oestrogen receptors at all phases of the oes... | ['Animals', 'Castration', 'Cell Nucleus', 'Estradiol', 'Estrus', 'Female', 'Hypothalamus', 'Pregnancy', 'Progesterone', 'Rats', 'Rats, Inbred Strains', 'Receptors, Estrogen', 'Uterus'] | 7,198,913 | [['B01.050'], ['E04.270.282', 'E04.950.165'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G08.686.195.500'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['G08.686.784.769'], ['D04.210.500.745.745.654.829', 'D06.472.334.734.623', 'D06.472.334.851.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Podoplanin promotes progression of malignant pleural mesothelioma by regulating motility and focus formation. | Malignant pleural mesothelioma (MPM) is characterized by dissemination and aggressive growth in the thoracic cavity. Podoplanin (PDPN) is an established diagnostic marker for MPM, but the function of PDPN in MPM is not fully understood. The purpose of this study was to determine the pathogenetic function of PDPN in MPM... | ['Adaptor Proteins, Signal Transducing', 'Animals', 'Blotting, Western', 'Cadherins', 'Cell Line, Tumor', 'Cell Movement', 'Disease Progression', 'Humans', 'Immunohistochemistry', 'Ki-67 Antigen', 'Membrane Glycoproteins', 'Mesothelioma', 'Mice, SCID', 'Phosphoproteins', 'Pleural Neoplasms', 'RNA Interference', 'Signal... | 28,182,302 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.18... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Endoscopic adenoidectomy in a case of Scheie syndrome (MPS I S). | The mucopolysaccharidoses (MPS) are a heterogeneous group of relatively rare, progressive, inherited lysosomal storage disorders, characterized by a deficiency of lysosomal enzymes which are responsible for the stepwise degradation of glycosaminoglycans. Their deficiency leads to the accumulation of glycosaminoglycans ... | ['Adenoidectomy', 'Adenoids', 'Child', 'Endoscopy', 'Female', 'Humans', 'Hypertrophy', 'Mucopolysaccharidosis I'] | 9,725,536 | [['E04.580.068'], ['A04.623.557.500', 'A10.549.100', 'A14.724.557.500', 'A15.382.520.604.100'], ['M01.060.406'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.775'], ['C16.320.565.202.715.640', 'C16.320.565.595.600.640', 'C17.300.550.575.640', 'C18.452.648.202.715.640', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of hypocholesterolemia and chronic hormonal stimulation on sterol and steroid metabolism in a Leydig cell tumor. | The studies presented herein were done to investigate the effects of drug-induced hypocholesterolemia and chronic hormonal stimulation on cholesterol metabolism and steroid biosynthesis in a functional Leydig cell tumor. It was found that 4-aminopyrazolo(3,4-d)-pyrimidine (4-APP)-induced hypocholesterolemia had no effe... | ['Adenine', 'Animals', 'Cholesterol', 'Chorionic Gonadotropin', 'Dyslipidemias', 'Kinetics', 'Leydig Cell Tumor', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Neoplasms, Experimental', 'Steroids', 'Sterols', 'Testicular Neoplasms'] | 7,320,635 | [['D03.633.100.759.138'], ['B01.050'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['C18.452.584.500'], ['G01.374.661', 'G02.111.490'], ['C04.557.475.750.847.249', 'C04.588.322.762.500.249', 'C04.588... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The spleen plays a central role in primary humoral alloimmunization to transfused mHEL red blood cells. | BACKGROUND: Several differences exist between antigens on transfused red blood cells (RBCs) and other immunogens, including anatomical compartmentalization. Whereas antigens from microbial pathogens and solid organ transplants drain into local lymph nodes, circulating RBCs remain segregated in the peripheral circulatio... | ['Animals', 'Antigen-Presenting Cells', 'CD4-Positive T-Lymphocytes', 'Chickens', 'Erythrocyte Transfusion', 'Erythrocytes', 'Immunity, Humoral', 'Immunization', 'Lymphocyte Activation', 'Mice', 'Mice, Transgenic', 'Muramidase', 'Spleen'] | 19,413,728 | [['B01.050'], ['A11.066', 'A15.382.066'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E02.095.135.140.275'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G12.450.050.420'], ['E02.095.465.425.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Synthesis, structure and biological evaluation of novel bicyclic nitroimidazole derivatives. | A new series of 3-hydroxy-8-nitroimidazo[5,1-b]-1,4,5,6-tetrahydropyrimidine systems, being potential tuberculostatic agents, were synthesized. These products are close structural analogs of the basic structure of the known antitubercular bicyclic nitroimidazooxazine PA-824. The structures of the products obtained were... | ['Antitubercular Agents', 'Bridged Bicyclo Compounds, Heterocyclic', 'Crystallography, X-Ray', 'Microbial Sensitivity Tests', 'Molecular Structure', 'Mycobacterium tuberculosis', 'Nitroimidazoles', 'Structure-Activity Relationship'] | 22,266,946 | [['D27.505.954.122.085.255'], ['D03.605.084'], ['E05.196.309.742.225'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['G02.111.570', 'G02.466'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['D02.640.672', 'D03.383.129.308.658'], ['G02.111.830', 'G07.690.773.997']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
6-Ketoprostaglandin F1 alpha, prostaglandins E2, F2 alpha and thromboxane B2 production by endothelial cells, smooth muscle cells and fibroblasts cultured from piglet aorta. | After [3H]arachidonic acid labeling, cyclooxygenase products were qualitatively analysed in the media of each cultured vascular cell type by reverse-phase high-performance liquid chromatography (rp-HPLC). The prostaglandin E2, prostaglandin F2 alpha, 6-ketoprostaglandin F1 alpha and thromboxane B2 detected in the rp-HP... | ['6-Ketoprostaglandin F1 alpha', 'Animals', 'Aorta', 'Arachidonic Acid', 'Arachidonic Acids', 'Cells, Cultured', 'Dinoprost', 'Dinoprostone', 'Endothelium', 'Fibroblast Growth Factors', 'Fibroblasts', 'Growth Substances', 'Kinetics', 'Muscle, Smooth, Vascular', 'Peptides', 'Prostaglandin-Endoperoxide Synthases', 'Prost... | 6,214,281 | [['D10.251.355.255.550.400.350', 'D10.251.355.325.450', 'D23.469.050.175.725.400.350'], ['B01.050'], ['A07.015.114.056'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['D10.251.355.255.100', 'D10.251.355.310.166'], ['A11.251'], ['D10.251.355.255.550.400.200', 'D23.469.050.175.725.400.200'], ['D10.251.355.255... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Targeting the cytosolic innate immune receptors RIG-I and MDA5 effectively counteracts cancer cell heterogeneity in glioblastoma. | Cellular heterogeneity, for example, the intratumoral coexistence of cancer cells with and without stem cell characteristics, represents a potential root of therapeutic resistance and a significant challenge for modern drug development in glioblastoma (GBM). We propose here that activation of the innate immune system b... | ['Antineoplastic Agents', 'Apoptosis', 'Brain Neoplasms', 'Cell Line, Tumor', 'Cytosol', 'DEAD Box Protein 58', 'DEAD-box RNA Helicases', 'Glioblastoma', 'Humans', 'Immunity, Innate', 'Interferon-Induced Helicase, IFIH1', 'Ligands', 'Signal Transduction', 'Stem Cells'] | 23,390,110 | [['D27.505.954.248'], ['G04.146.954.035'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D08.811.913.696.445.735.720.249.750'], ['D08.811.913.696.445.735.720.249'], ['C04.557.465.625.600.380... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Analgesics in geriatric patients. Adverse side effects and interactions]. | Pain is a widespread symptom in clinical practice. Older adults and chronically ill patients are particularly affected. In multimorbid geriatric patients, pharmacological pain treatment is an extension of a previously existing multimedication. Besides the efficacy of pain treatment, drug side effects and drug-drug inte... | ['Aged', 'Aged, 80 and over', 'Analgesics', 'Antidepressive Agents', 'Chemical and Drug Induced Liver Injury', 'Drug Interactions', 'Female', 'Humans', 'Male', 'Serotonin Syndrome'] | 26,152,872 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['D27.505.954.427.700.122'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['G07.690.773.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C25.100.875']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A panel data analysis of the relationships of nursing home staffing levels and standards to regulatory deficiencies. | OBJECTIVE: To examine the relationships between nursing staffing levels and nursing home deficiencies.METHODS: This panel data analysis employed random-effect models that adjusted for unobserved, nursing home-specific heterogeneity over time. Data were obtained from California's long-term care annual cost report data a... | ['Aged', 'Aged, 80 and over', 'California', 'Health Care Surveys', 'Homes for the Aged', 'Humans', 'Nursing Homes', 'Nursing Staff', 'Quality Indicators, Health Care', 'Quality of Health Care', 'Reference Standards', 'Safety Management', 'Workforce'] | 19,181,692 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['J03.775.462', 'N02.278.825.462'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.825.610']... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Differentiating sibling species of Zeugodacus caudatus (Insecta: Tephritidae) by complete mitochondrial genome. | Zeugodacus caudatus is a pest of pumpkin flowers. It has a Palearctic and Oriental distribution. We report here the complete mitochondrial genome of the Malaysian and Indonesian samples of Z. caudatus determined by next-generation sequencing of genomic DNA and determine their taxonomic status as sibling species and phy... | ['Animals', 'Genetic Structures', 'Genetic Variation', 'Genome Size', 'Genome, Mitochondrial', 'High-Throughput Nucleotide Sequencing', 'Indonesia', 'Malaysia', 'Male', 'Open Reading Frames', 'Phylogeny', 'Siblings', 'Tephritidae'] | 27,502,829 | [['B01.050'], ['G05.360'], ['G05.365'], ['G05.360.340.037'], ['G05.360.340.360'], ['E05.393.760.319'], ['Z01.252.145.380', 'Z01.639.580'], ['Z01.252.145.487'], ['G05.360.335.760.640', 'G05.360.340.024.340.137.650'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['F01.829.263.500.490', 'I01.880.853.150.500.505', 'M01.781']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 |
Bioactive phenolic compounds from a medicinal lichen, Usnea longissima. | Natural products, longissiminone A (1) and longissiminone B (2), were isolated along with a known compound, glutinol (3), from a medicinal lichen, Usnea longissima. The structures of compounds 1 and 2 were determined with the help of spectroscopic studies. Compound 1 was found to possess potent anti-inflammatory activi... | ['Anti-Inflammatory Agents, Non-Steroidal', 'Benzene Derivatives', 'Cell Survival', 'Dose-Response Relationship, Drug', 'Humans', 'Molecular Structure', 'Neutrophils', 'Triterpenes', 'Usnea'] | 16,102,789 | [['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D02.455.426.559.389'], ['G04.346'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570', 'G02.466'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.58... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The effect of stimulation of the ocular muscles on the formation of visual responses in the cat lateral geniculate body]. | It has been shown in acute experiments on anesthetized cats that stimulation of the ocular muscles by single current pulse caused different changes in formation of negative and positive components of the visual response of the lateral geniculate nucleus. It was established that character of those changes depended on th... | ['Animals', 'Cats', 'Electric Stimulation', 'Evoked Potentials, Visual', 'Geniculate Bodies', 'Oculomotor Muscles', 'Photic Stimulation', 'Reaction Time', 'Saccades', 'Time Factors', 'Visual Perception'] | 1,922,564 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['E05.723.402'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['A08.186.211.200.317.826.701.444'], ['A02.633.567.700'], ['E05.723.729'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['G14.350.500'], ['G01.910.857'], ['F02.463.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dynamics of a lipid bilayer induced by electric fields. | The dynamics of a lipid bilayer of 1-palmitoyl-2-oleoyl-glycero-3-phospho-ethanolamine, POPE, is investigated under the effect of two electric field intensities. The box of 720 lipids and 13,458 water molecules-plus boundary conditions-undergoes similar re-organizational dynamics in the presence of fields of 0.35 V nm(... | ['Electricity', 'Kinetics', 'Lipid Bilayers', 'Molecular Dynamics Simulation', 'Phosphatidylethanolamines', 'Water'] | 21,468,426 | [['G01.358.500.249'], ['G01.374.661', 'G02.111.490'], ['D10.570.510', 'J01.637.087.500.510'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D10.570.755.375.760.400.840'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Epidemiology of hypertension associated with diabetes mellitus. | The clinical impression of an association between hypertension and diabetes mellitus has not been consistently confirmed by epidemiological studies. The variety of methodological problems in this area of research includes the choice of appropriate patient and control groups, the measurement techniques used, and conside... | ['Adult', 'Antihypertensive Agents', 'Diabetes Complications', 'Diabetes Mellitus', 'Epidemiologic Methods', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Risk'] | 4,077,239 | [['M01.060.116'], ['D27.505.954.411.162'], ['C19.246.099'], ['C18.452.394.750', 'C19.246'], ['E05.318', 'N06.850.520'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600.800']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Non-random, individual-specific methylation profiles are present at the sixth CTCF binding site in the human H19/IGF2 imprinting control region. | Expression of imprinted genes is classically associated with differential methylation of specific CpG-rich DNA regions (DMRs). The H19/IGF2 locus is considered a paradigm for epigenetic regulation. In mice, as in humans, the essential H19 DMR--target of the CTCF insulator--is located between the two genes. Here, we per... | ['Binding Sites', 'CCCTC-Binding Factor', 'CpG Islands', 'DNA Methylation', 'DNA-Binding Proteins', 'Female', 'Gene Expression', 'Genomic Imprinting', 'Genotype', 'Humans', 'Infant, Newborn', 'Inheritance Patterns', 'Insulin-Like Growth Factor II', 'Male', 'Models, Genetic', 'Pedigree', 'Placenta', 'Polymerase Chain Re... | 17,012,269 | [['G02.111.570.120'], ['D12.776.157.687.157', 'D12.776.260.120', 'D12.776.660.235.050', 'D12.776.660.720.157', 'D12.776.664.235.050', 'D12.776.930.780.563'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['D12.776.260'], ... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Primaquine metabolism by human liver microsomes: effect of other antimalarial drugs. | A number of drugs have been studied for their effect on the metabolism of the antimalarial drug primaquine by human liver microsomes (N = 4) in vitro. The only metabolite generated was identified as carboxyprimaquine by co-chromatography with the authentic standard. Ketoconazole, a known inhibitor of cytochrome P450 is... | ['Antimalarials', 'Cytochrome P-450 Enzyme Inhibitors', 'Cytochrome P-450 Enzyme System', 'Drug Interactions', 'Humans', 'Isoenzymes', 'Kinetics', 'Microsomes, Liver', 'NADP', 'Primaquine'] | 1,510,705 | [['D27.505.954.122.250.100.085'], ['D27.505.389.500', 'D27.505.519.389.335'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['G07.690.773.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.348', 'D12.776.800.300'], ['G01.374.661', 'G02.111.490'], ['A11.284.835.540.541'], ['D03.633.10... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Measurement of azygos venous blood flow by a continuous thermal dilution technique: an index of blood flow through gastroesophageal collaterals in cirrhosis. | A method to quantitate blood flow through the gastroesophageal collaterals in portal hypertensive patients was developed. Since gastroesophageal collaterals drain into the azygos system, it is postulated that measurement of blood flow in the azygos vein should provide a quantitative measurement of gastroesophageal coll... | ['Azygos Vein', 'Blood Flow Velocity', 'Esophageal and Gastric Varices', 'Gastrointestinal Hemorrhage', 'Humans', 'Hypertension, Portal', 'Liver Cirrhosis, Alcoholic', 'Regional Blood Flow', 'Stomach', 'Thermodilution', 'Valsalva Maneuver', 'Varicose Veins'] | 6,609,870 | [['A07.015.908.106'], ['E01.370.370.130', 'G09.330.380.630.080'], ['C06.405.117.240', 'C06.552.494.414'], ['C06.405.227', 'C23.550.414.788'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.494'], ['C06.552.630.380', 'C06.552.645.590', 'C23.550.355.412.380', 'C25.775.100.087.645.550'], ['G09.330.100.780'], [... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of routine intraoperative transesophageal echocardiography on surgical management. | OBJECTIVE: To assess the effects of routine intraoperative transesophageal echocardiography (TEE) on surgical management of patients undergoing all types of cardiac surgery.DESIGN: Prospective, observational.SETTING: A single-institution, clinical investigation, university-affiliated hospital.PARTICIPANTS: Two hundred ... | ['Cardiac Surgical Procedures', 'Decision Making', 'Echocardiography, Transesophageal', 'Heart Valve Diseases', 'Humans', 'Intraoperative Care', 'Mitral Valve', 'Prospective Studies', 'Tricuspid Valve'] | 18,068,055 | [['E04.100.376', 'E04.928.220'], ['F02.463.785.373'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['C14.280.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.731.400', 'E04.604.249', 'N02.421.585.722.400'], ['A07.541.510.507'], ['E05.318.372.500.750.625', 'N05.715.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Beware the rooster: smokeless tobacco companies who claim they want to help. | It should not be assumed that smokeless tobacco manufacturers share our public health goals | ['Advertising', 'Goals', 'Humans', 'Public Health', 'Tobacco Industry', 'Tobacco, Smokeless'] | 14,660,754 | [['J01.219.687.274', 'L01.143.050'], ['F01.658.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['J01.576.655.968'], ['J01.637.767.844.500']] | ['Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
[The selenium content of food products and the blood of inhabitants of Norilsk]. | The intake of trace element selenium by Norilsk citizens was assessed by its levels in the serum, food and soil. It was found that soil and food made in the Norilsk region are rich in selenium, its serum concentration in the population is normal (102 micrograms/l). References to such values for the Moscow and Zaporoje ... | ['Female', 'Food Analysis', 'Humans', 'Male', 'Russia', 'Selenium', 'Soil'] | 1,462,516 | [['E05.362', 'J01.576.423.850.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.122.500', 'Z01.542.248.775'], ['D01.268.185.850', 'D01.578.700'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice. | OBJECTIVE AND DESIGN: Cystic fibrosis transmembrane conductance regulator (CFTR) regulates infection and inflammation. In this study, we investigated whether a lack of functional CFTR in neutrophils would promote lipopolysaccharide (LPS)-induced lung inflammation and injury.MATERIALS AND METHODS: CFTR-inhibited or F508... | ['Animals', 'Bronchoalveolar Lavage Fluid', 'Cells, Cultured', 'Cystic Fibrosis Transmembrane Conductance Regulator', 'Lipopolysaccharides', 'Lung', 'Mice', 'Mice, Knockout', 'NF-kappa B', 'Neutrophils', 'Pneumonia'] | 21,301,926 | [['B01.050'], ['E05.927.100.500'], ['A11.251'], ['D12.776.157.530.100.304.500', 'D12.776.157.530.400.175.125', 'D12.776.157.530.450.074.500.500.500.500', 'D12.776.543.550.450.175.125', 'D12.776.543.585.100.304.500', 'D12.776.543.585.400.175.125', 'D12.776.543.585.450.074.500.500.500.500'], ['D09.400.500', 'D09.698.718.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of carbon source succession on laccase activity in the co-culture process of Ganoderma lucidum and a yeast. | In the present paper, the mechanism of overproduction of laccase by microbe interaction was investigated in the co-culture process of Ganoderma lucidum and Candida sp. HSD07A. The results show that nitrogen source, sulfur source, hydrolytic enzymes and inducers do not have the significant influence on laccase activity,... | ['Biotechnology', 'Candida', 'Carbon', 'Coculture Techniques', 'Culture Media', 'Fermentation', 'Glucose', 'Glycerol', 'Laccase', 'Reishi'] | 22,112,763 | [['H01.158.550', 'J01.897.120'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['D01.268.150'], ['E05.481.500.374'], ['D27.720.470.305', 'E07.206'], ['G02.111.158.249', 'G03.191.249'], ['D09.947.875.359.448'], ['D02.033.800.875.500', 'D09.853.875.500'], ['D08.811.682.494'], ['B01.300.179.120.760.338.70... | ['Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
RREB1-induced upregulation of the lncRNA AGAP2-AS1 regulates the proliferation and migration of pancreatic cancer partly through suppressing ANKRD1 and ANGPTL4. | Long noncoding RNAs (lncRNAs) have been reported to be involved in a variety of human diseases, including cancers. However, their mechanisms have not yet been fully elucidated. We investigated lncRNA changes that may be associated with pancreatic cancer (PC) by analyzing published microarray data, and identified AGAP2-... | ['Angiopoietin-like 4 Protein', 'Animals', 'Carcinoma, Pancreatic Ductal', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'DNA-Binding Proteins', 'Female', 'Heterografts', 'Humans', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Middle Aged', 'Muscle Proteins', 'Nuclear Proteins', 'Pancreatic Neoplasms', 'Pr... | 30,814,490 | [['D12.644.276.100.050.500', 'D12.776.467.100.050.500', 'D23.529.100.050.500'], ['B01.050'], ['C04.557.470.200.025.232.750', 'C04.557.470.615.132.750', 'C04.588.274.761.750', 'C04.588.322.475.750', 'C06.301.761.750', 'C06.689.667.625', 'C19.344.421.750'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Identification of different molecular forms of human airway lysozyme. | Human airway lysozyme (HAL) was separated into fractions of distinct molecular forms using a Mono S cation-exchange column on a fast-protein liquid chromatography system. This new and rapid (30 min) purification procedure of human lysozyme enabled the preparation of fractions, highly enriched in different isoenzymes of... | ['Chromatography, Ion Exchange', 'Isoenzymes', 'Lung', 'Molecular Weight', 'Muramidase', 'Sputum', 'Trachea'] | 3,565,753 | [['E05.196.181.400.383'], ['D08.811.348', 'D12.776.800.300'], ['A04.411'], ['G02.494'], ['D08.811.277.450.642'], ['A12.200.808'], ['A04.889']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.