Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Regeneration of aged DMF for use in solid-phase peptide synthesis. | Dimethylformamide (DMF), which is still the most commonly used solvent for Fmoc-SPPS, has the potential for degradation over time on exposure to air (and water vapour) and storage, to give dimethylamine and formic acid impurities. In particular, dimethylamine can lead to unwanted deprotection of the fluorenylmethyloxyc... | ['Dimethylamines', 'Dimethylformamide', 'Drug Stability', 'Equipment Reuse', 'Fluorenes', 'Formates', 'Kinetics', 'Nitrogen', 'Oxidation-Reduction', 'Resins, Synthetic', 'Solid-Phase Synthesis Techniques', 'Solvents', 'Sonication'] | 30,585,396 | [['D02.092.668.387'], ['D02.065.463.387', 'D02.241.081.420.500.387'], ['E05.916.330'], ['E05.328', 'N06.850.585'], ['D02.455.426.559.847.389', 'D04.615.389'], ['D02.241.081.420'], ['G01.374.661', 'G02.111.490'], ['D01.268.604', 'D01.362.625'], ['G02.700', 'G03.295.531'], ['D05.750.716.822', 'D25.339.816', 'D25.720.716.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Optimisation of a double-centrifugation method for preparation of canine platelet-rich plasma. | BACKGROUND: Platelet-rich plasma (PRP) has been expected for regenerative medicine because of its growth factors. However, there is considerable variability in the recovery and yield of platelets and the concentration of growth factors in PRP preparations. The aim of this study was to identify optimal relative centrifu... | ['Animals', 'Becaplermin', 'Cell Separation', 'Centrifugation', 'Dogs', 'Male', 'Platelet-Rich Plasma', 'Proto-Oncogene Proteins c-sis'] | 28,651,609 | [['B01.050'], ['D12.644.276.910.650.500', 'D12.776.260.690.500', 'D12.776.467.910.650.500', 'D23.529.910.650.500'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E05.181'], ['B01.050.150.900.649.313.750.250.216.200'], ['A12.207.152.693.600', 'A12.207.270.695.600', 'A15.145.693.600'], ['D12.644.276.910.65... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Warm white light from Y4MgSi3O13:Bi3+, Eu3+ nanophosphor for white light-emitting diodes. | Y(4)MgSi(3)O(13):Bi(3+), Eu(3+) nanophosphors have been prepared by a facile sol-gel method. The products have been characterized by X-ray diffraction, field-emission scanning electron microscopy and fluorescence measurements. The results show that the nanophosphors are of single phase hexagonal Y(4)MgSi(3)O(13) with s... | ['Bismuth', 'Europium', 'Fluorescence', 'Light', 'Lighting', 'Microscopy, Electron, Scanning', 'Nanostructures', 'Phase Transition', 'Silicates', 'X-Ray Diffraction'] | 19,615,932 | [['D01.268.271.245', 'D01.268.556.100', 'D01.496.749.305.245', 'D01.552.544.100'], ['D01.268.558.362.468', 'D01.552.550.399.468'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['N06.230.150.410'], ['E01.370.350.515.402.541', 'E05.5... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Aflatoxin levels in sunflower seeds and cakes collected from micro- and small-scale sunflower oil processors in Tanzania. | Aflatoxin, a mycotoxin found commonly in maize and peanuts worldwide, is associated with liver cancer, acute toxicosis, and growth impairment in humans and animals. In Tanzania, sunflower seeds are a source of snacks, cooking oil, and animal feed. These seeds are a potential source of aflatoxin contamination. However, ... | ['Aflatoxins', 'Food Contamination', 'Food Microbiology', 'Helianthus', 'Plant Oils', 'Seeds', 'Sunflower Oil', 'Tanzania'] | 28,419,131 | [['D03.383.663.283.119', 'D03.633.100.150.119', 'D23.946.587.142'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['B01.650.940.800.575.912.250.100.400'], ['D... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Repair of burns of the scrotum using a gracilis myocutaneous flap. | An unusual case of isolated burns of the scrotum reconstructed by a unilateral gracilis myocutaneous flap is reported because of its clinical rarity. | ['Adult', 'Burns', 'Humans', 'Male', 'Scrotum', 'Surgical Flaps'] | 2,757,768 | [['M01.060.116'], ['C26.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.360.444.661'], ['A10.850.710', 'E07.862.710']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Enhancing generalized teaching strategy use in daily routines by parents of children with autism. | PURPOSE: The purpose of this study was to examine the effects of facilitating generalized use of teaching strategies by parents of children with autism within daily routines.METHOD: Five preschool children with autism participated in intervention with a parent within daily routines in the family's home. Parents learned... | ['Activities of Daily Living', 'Autistic Disorder', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Language Therapy', 'Male', 'Parents', 'Reproducibility of Results', 'Speech Production Measurement', 'Teaching', 'Videotape Recording'] | 16,787,891 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['F03.625.164.113.500'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.169.063.500.727.344', 'E02.831.727.344'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['E05.318.370.725'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 |
Detoxication disturbances and uncoupling effects in vitro of some chlorinated guaiacols, catechols and benzoquinones. | The effects of chlorinated guaiacols, catechols and benzoquinones - earlier identified in discharges from pulp and paper mills -- on oxidative phosphorylation in mitochondria and on detoxication mechanisms in microsomes have been investigated. The same biological systems have been used in testing outgoing water from a ... | ['Animals', 'Catechols', 'Chloranil', 'Glutamates', 'Guaiacol', 'Inactivation, Metabolic', 'Malates', 'Male', 'Microsomes, Liver', 'Mitochondria, Liver', 'Oxygen Consumption', 'Quinones', 'Rats', 'Uncoupling Agents', 'Water Pollutants', 'Water Pollutants, Chemical'] | 7,428,119 | [['B01.050'], ['D02.455.426.559.389.657.166'], ['D02.806.250.210'], ['D12.125.067.625', 'D12.125.119.409'], ['D02.355.601.536', 'D02.355.726.453', 'D02.455.426.559.389.657.166.453', 'D02.455.426.559.389.657.654.453'], ['G03.171.450', 'G03.787.225.450', 'G07.690.725.225.450'], ['D02.241.081.337.463', 'D02.241.511.505'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An analysis of current source density profiles activated by local stimulation in the mouse auditory cortex in vitro. | To examine local network properties of the mouse auditory cortex in vitro, we recorded extracellular spatiotemporal laminar profiles driven by short electric local stimulation on a planar multielectrode array substrate. The recorded local field potentials were subsequently evaluated using current source density (CSD) a... | ['Aging', 'Animals', 'Auditory Cortex', 'Cluster Analysis', 'Electric Stimulation', 'Evoked Potentials, Auditory, Brain Stem', 'Linear Models', 'Male', 'Mice, Inbred C57BL', 'Mice, Mutant Strains', 'Microelectrodes', 'Principal Component Analysis', 'Signal Processing, Computer-Assisted', 'Tissue Culture Techniques'] | 28,119,054 | [['G07.345.124'], ['B01.050'], ['A08.186.211.200.885.287.500.814.249', 'A08.186.211.200.885.287.500.863.297'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.723.402'], ['G07.265.216.500.370.300', 'G07.888.250.300', 'G11.561.200.500.370.300'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E0... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Berchemiosides A-C, 2-Acetoxy-ù-phenylpentaene Fatty Acid Triglycosides from the Unripe Fruits of Berchemia berchemiifolia. | Three compounds in a new class of 2-acetoxy-ù-phenylpentaene fatty acid triglycosides, berchemiosides A-C (1-3), and a biosynthetically related phenolic glycoside (4) were isolated from the unripe fruits of Berchemia berchemiifolia, along with three flavonoid 5-O-diglycosides (5-7) and three known flavonoids (8-10). Th... | ['Fatty Acids, Unsaturated', 'Flavonoids', 'Fruit', 'Glycosides', 'Molecular Structure', 'Nuclear Magnetic Resonance, Biomolecular', 'Rhamnaceae', 'Stereoisomerism', 'Structure-Activity Relationship', 'Xanthine Oxidase'] | 28,972,762 | [['D10.251.355'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['D09.408'], ['G02.111.570', 'G02.466'], ['E05.196.867.519.550'], ['B01.650.940.800.575.912.250.859.937.437'], ['G02.607.445.682'], ['G02.111.830', 'G07.690.773.997'], ['D08.811.682.047.928']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Endocardial irregularities of the left atrial roof as seen on coronary CT angiography. | OBJECTIVE: To describe and characterize morphological characteristics of endocardial irregularities in the roof of the left atrium as seen on coronary CT angiography.METHODS: We retrospectively evaluated the left atrium in 50 consecutive coronary CT patients with multiplanar reformatting, volume rendering, and virtual ... | ['Coronary Angiography', 'Diverticulum', 'Female', 'Heart Atria', 'Humans', 'Image Processing, Computer-Assisted', 'Male', 'Middle Aged', 'Retrospective Studies', 'Tomography, X-Ray Computed'] | 18,463,987 | [['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C06.405.205.282.750', 'C23.300.415'], ['A07.541.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Human tissue factor pathway inhibitor-2 is internalized by cells and translocated to the nucleus by the importin system. | Tissue factor pathway inhibitor-2 (TFPI-2) is a serine proteinase inhibitor that induces caspase-mediated apoptosis when offered to a variety of tumor cells. In order to investigate the mechanism of TFPI-2-induced apoptosis, we initially studied the uptake and trafficking of TFPI-2 by HT-1080 cells. Exogenously offered... | ['Aorta', 'Apoptosis', 'Capillaries', 'Cell Line', 'Cell Line, Tumor', 'Cell Nucleus', 'Endothelium, Vascular', 'Fibrosarcoma', 'Glycoproteins', 'Humans', 'Karyopherins', 'Kidney', 'Kinetics', 'Microscopy, Confocal', 'Plasmids', 'Polymerase Chain Reaction', 'Recombinant Proteins', 'Skin', 'Transfection'] | 19,103,149 | [['A07.015.114.056'], ['G04.146.954.035'], ['A07.015.461.165'], ['A11.251.210'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A07.015.700.500', 'A10.272.491.355'], ['C04.557.450.565.590.350', 'C04.557.450.795.350'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.3... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Auditory evoked potentials in postconcussive syndrome. | The neuropsychiatric sequelae of minor head trauma have been the source of controversy. Most clinical and imaging studies have shown no alteration after concussion, but neuropsychological and neuropathological abnormalities have been reported. Some changes in neurophysiologic diagnostic tests have been described in pos... | ['Adult', 'Brain Concussion', 'Evoked Potentials, Auditory', 'Female', 'Humans', 'Male', 'Middle Aged', 'Reaction Time'] | 8,985,672 | [['M01.060.116'], ['C10.228.140.199.444.250', 'C10.900.300.087.235.250', 'C10.900.300.350.300', 'C26.915.300.200.194.250', 'C26.915.300.450.500', 'C26.974.382.200'], ['G07.265.216.500.370', 'G07.888.250', 'G11.561.200.500.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.796.817', 'F02.... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Student coping strategies and perceptions of fieldwork. | A questionnaire, the revised Ways of Coping Checklist, was sent to all professional (entry-level) graduate students in the United States in one academic year during their second fieldwork level II experience to determine what coping strategies they used during their fieldwork experience. Information was also gathered r... | ['Adaptation, Psychological', 'Adult', 'Education, Graduate', 'Female', 'Humans', 'Internship, Nonmedical', 'Male', 'Occupational Therapy', 'Problem Solving', 'Social Support', 'Speech Therapy', 'Students'] | 8,506,935 | [['F01.058'], ['M01.060.116'], ['I02.358.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.750'], ['E02.760.169.063.500.489', 'E02.831.489', 'H02.010.500'], ['F02.463.425.725', 'F02.463.785.810'], ['I01.880.853.500.600'], ['E02.760.169.063.500.727.552', 'E02.831.727.552'], ['M01.848']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
Interactive effects of water limitation and elevated temperature on the physiology, development and fitness of diverse accessions of Brachypodium distachyon. | An enduring question in plant physiology and evolution is how single genotypes of plants optimize performance in diverse, often highly variable, environments. We grew 35 natural accessions of the grass Brachypodium distachyon in four environments in the glasshouse, contrasting soil water deficit, elevated temperature a... | ['Biodiversity', 'Brachypodium', 'Climate', 'Genotype', 'Inheritance Patterns', 'Models, Biological', 'Quantitative Trait, Heritable', 'Soil', 'Temperature', 'Water'] | 27,864,966 | [['G16.500.275.157.049', 'N06.230.124.049'], ['B01.650.940.800.575.912.250.822.072'], ['G16.500.275.071', 'N06.230.300.100.250'], ['G05.380'], ['G05.420'], ['E05.599.395'], ['G05.420.720'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Perceptions of the value of hospital residency and clinical medicine in dental education. | A survey of the outlook of 81 participating dental undergraduates concerning the value of a general hospital residency programme has been compared with the perceptions of 240 graduate health professionals (dental and medical practitioners, registered nurses and others). There is convincing statistical evidence of pan-p... | ['Curriculum', 'Education, Dental', 'Education, Medical', 'Humans', 'Internship and Residency', 'Interprofessional Relations', 'New South Wales', 'Surveys and Questionnaires'] | 2,775,022 | [['I02.158'], ['I02.358.274'], ['I02.358.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['F01.829.401.205'], ['Z01.639.100.750', 'Z01.678.100.373.750'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Radiographic analysis of deep cervical abscesses. | Correlation of the radiographic examination and the clinical evaluation of deep cervical abscesses contributes to the surgical program for exposure and drainage. The deep cervical spaces are analyzed with reference to local anatomy, sources of infection, potential for lateral and vertical extension, and identification ... | ['Abscess', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neck', 'Tomography, X-Ray Computed'] | 1,416,641 | [['C01.830.025', 'C23.550.470.756.100'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A01.598'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.37... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Notes on a nodular disease of the intestine of the open-billed stork--(Anastomus oscitans) caused by Chaunouephalus ferox. | An account is given of the pathology of open-billed storks, Anastomus oscitans, suggested that the parasitic trematodes host. of nodular lesions in the small intestine caused by Chaunocephalus ferox. It is lead an entirely histiozoic life in this | ['Animals', 'Animals, Zoo', 'Bird Diseases', 'Birds', 'Female', 'Intestines', 'Male', 'Trematoda', 'Trematode Infections'] | 16,509,132 | [['B01.050'], ['B01.050.050.448'], ['C22.131'], ['B01.050.150.900.248'], ['A03.556.124'], ['B01.050.500.500.736.715'], ['C01.610.335.865']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Restorative considerations in the dental treatment of the older patient. | The older person and his or her dentition will have a clinical presentation and a reaction to treatment that is influenced by his or her unique blend of aging and disease processes. Changes seen in enamel, dentin, pulp, and cementum of the older patient are described in terms of their causes and the impacts of the chan... | ['Acid Etching, Dental', 'Aged', 'Aging', 'Chronic Disease', 'Dental Bonding', 'Dental Care for Aged', 'Dental Cementum', 'Dental Enamel', 'Dental Pulp', 'Dental Restoration, Permanent', 'Dentin', 'Female', 'Humans', 'Male', 'Patient Care Planning', 'Stress, Physiological', 'Tooth Diseases'] | 11,199,635 | [['E06.931.475.111'], ['M01.060.116.100'], ['G07.345.124'], ['C23.550.291.500'], ['E06.095'], ['E06.170.100', 'N02.421.240.190.210'], ['A14.549.167.646.267', 'A14.549.167.900.250'], ['A14.549.167.900.255'], ['A14.549.167.900.260'], ['E06.323.428', 'E06.780.346.737', 'E07.695.190.190'], ['A14.549.167.900.280'], ['B01.05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Steroid regulation of somatostatin mRNA in the rat hypothalamus. | The participation of gonadal steroid hormones in the regulation of the expression of the somatostatin gene in the hypothalamus and cerebral cortex was studied by using a quantitative densitometric hybridization assay which allows the direct measurement of specific somatostatin mRNA levels. The levels of somatostatin mR... | ['Animals', 'Female', 'Gonadal Steroid Hormones', 'Hypothalamus', 'Male', 'Nucleic Acid Hybridization', 'RNA, Messenger', 'Rats', 'Rats, Inbred Strains', 'Somatostatin'] | 2,897,361 | [['B01.050'], ['D06.472.334.851'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['E05.393.661', 'G02.111.611'], ['D13.444.735.544'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D06.472.699.327.700.875', 'D06.472.699.587.780', 'D12.644... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Is tensegrity a unifying concept of protein folds? | We suggest that the three-dimensional architecture of globular proteins can be described in terms of tensegrets, i.e. structural elements that are held together through attractive and repulsive forces. Hard elements of tensegrets are represented by secondary structure elements, i.e. alpha-helices and beta-strands, whil... | ['Fullerenes', 'Models, Molecular', 'Myoglobin', 'Protein Folding'] | 12,527,354 | [['D01.268.150.250', 'J01.637.512.600.612.350'], ['E05.599.595'], ['D12.776.210.500.588', 'D12.776.422.316.940'], ['G01.154.651', 'G02.111.688']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Inhibition of DNA polymerase alpha by gossypol. | Our earlier studies have shown that gossypol is a specific inhibitor of DNA synthesis in cultured cells at low doses. In an attempt to determine the mechanism for the inhibition of DNA synthesis by gossypol we observed that gossypol does not interact with DNA per se but may affect some of the enzymes involved in DNA re... | ['DNA Polymerase I', 'DNA Polymerase II', 'DNA Polymerase III', 'Dithiothreitol', 'Ferrous Compounds', 'Free Radicals', 'Gossypol', 'Humans', 'Kinetics', 'Thymidine', 'Tritium'] | 3,697,356 | [['D08.811.913.696.445.308.300.225'], ['D08.811.913.696.445.308.300.230'], ['D08.811.913.696.445.308.300.235'], ['D02.033.800.196', 'D02.886.740.224', 'D09.853.196'], ['D01.490.200'], ['D01.339', 'D02.389'], ['D02.455.849.765.444'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D03.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Induction of hepatic microsomal drug-metabolizing enzymes by inhibitors of 5-lipoxygenase (5-LO): studies in rats and 5-LO knockout mice. | The effect of 5-lipoxygenase (5-LO) inhibitors on the hepatic microsomal mixed-function oxidase (MFO) system of rodents was investigated. After establishing the relative in vitro and in vivo potencies of the 3 test compounds, male Crl:CD (SD) BR rats received CJ-11,802 (0, 10, 50, or 200 mg/kg/day), zileuton (0, 10, 60... | ['Animals', 'Arachidonate 5-Lipoxygenase', 'Cytochrome P-450 Enzyme System', 'Dose-Response Relationship, Drug', 'Enzyme Induction', 'Hydroxyurea', 'Lipoxygenase Inhibitors', 'Liver', 'Male', 'Mice', 'Mice, Inbred DBA', 'Mice, Knockout', 'Microsomes, Liver', 'NADH Dehydrogenase', 'Organ Size', 'Pyrans', 'Quinolones', '... | 11,509,739 | [['B01.050'], ['D08.811.682.690.416.583.500.055', 'D12.776.556.579.374.568.500.020'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['G07.690.773.875', 'G07.690.936.500'], ['G05.308.320.200'], ['D02.065.950.395'], ['D27.505.519.389.480'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Is a two-week trial of oral prednisolone predictive of target lung function in pediatric asthma? | We used a 2-week trial of prednisolone to determine "target" lung function for subsequent asthma therapy. The aim of this study was to evaluate whether some children exceed their "target" forced expired volume in 1 sec (FEV1) on subsequent visits in the following year, and whether this is associated with particular cli... | ['Adolescent', 'Anti-Inflammatory Agents', 'Asthma', 'Basement Membrane', 'Child', 'Drug Administration Schedule', 'Female', 'Follow-Up Studies', 'Humans', 'Lung', 'Male', 'Prednisolone', 'Respiratory Function Tests', 'Treatment Outcome'] | 15,765,544 | [['M01.060.057'], ['D27.505.954.158'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['A10.272.220', 'A10.615.179'], ['M01.060.406'], ['E02.319.283'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A simple and defined method to study calcification by isolated matrix vesicles. Effect of ATP and vesicle phosphatase. | A simplified and defined system was developed to study in vitro calcium phosphate deposition by isolated matrix vesicles from rabbit growth plate cartilage, and to examine the relationship between vesicle phosphatase and calcium deposition. Samples of suspended vesicles containing 25 microgram of protein, were incubate... | ['Adenine Nucleotides', 'Adenosine Triphosphatases', 'Adenosine Triphosphate', 'Animals', 'Bone Matrix', 'Calcification, Physiologic', 'Calcium', 'Hot Temperature', 'Magnesium', 'Phosphates', 'Phosphoric Monoester Hydrolases', 'Potassium', 'Rabbits', 'Sodium'] | 200,279 | [['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['D08.811.277.040.025'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A10.165.265.166'], ['G07.345.155.500', 'G07.345.500.325.377.625.050.500.175', 'G11.427.578.050.500.175'], ['D01.268.552.100', 'D01.55... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pancreatic transplantation using the duct occlusion technique. | Since 1979, the Munich Group has gathered experience with 100 consecutive pancreas transplants using the duct occlusion technique. At the present time, 40 of the pancreas grafts (44%) and 56 of the renal grafts (65%) of 90 patients who received both a pancreas and a kidney are still functioning. The mortality rate of 1... | ['Cyclosporins', 'Diabetes Mellitus, Type 1', 'Diabetic Neuropathies', 'Diabetic Retinopathy', 'Germany, West', 'Graft Survival', 'Humans', 'Insulin', 'Insulin Secretion', 'Kidney Transplantation', 'Pancreas', 'Pancreas Transplantation', 'Pancreatic Ducts', 'Phenylpropanolamine'] | 3,154,496 | [['D04.345.566.235', 'D12.644.641.235'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C10.668.829.300', 'C19.246.099.937'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['Z01.586.350'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.6... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
The N-terminal portion of domain E of retinoic acid receptors alpha and beta is essential for the recognition of retinoic acid and various analogs. | Utilizing a strategy involving domain exchange between retinoic acid receptors alpha and beta (RAR alpha and RAR beta) and monitoring the transcriptional activity of the resulting chimeric receptors with receptor-selective retinoids, we identified a 70-aa region within the N-terminal portion of the RAR alpha and -beta ... | ['Amino Acid Sequence', 'Binding Sites', 'Cloning, Molecular', 'Consensus Sequence', 'Escherichia coli', 'HeLa Cells', 'Humans', 'Kinetics', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Protein Structure, Secondary', 'Receptors, Retinoic Acid', 'Recombinant Fusion Proteins', 'Retinoic Acid Receptor alpha', ... | 7,892,182 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['E05.393.220'], ['G02.111.570.580.175'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['L01.453.24... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Promoter polymorphism MMP-1 (-1607 2G/1G) and MMP-3 (-1612 5A/6A) in development of HAND and modulation of pathogenesis of HAND. | The pathogenesis of HIV-associated neurocognitive disorder (HAND) is modulated by host genetic susceptibility factors such as Matrix metalloproteinases (MMPs). Promoter polymorphism of MMP-1 and MMP-3 may modify the expression of the gene. Hence, we evaluated the association of MMP-1-16072G/1G and MMP-3-1612 5A/6A poly... | ['AIDS Dementia Complex', 'Adult', 'Alleles', 'Case-Control Studies', 'Disease Progression', 'Female', 'Gene Expression', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Haplotypes', 'Humans', 'Male', 'Matrix Metalloproteinase 1', 'Matrix Metalloproteinase 3', 'Middle Aged', 'Odds Ratio', 'Polymorphism, Single ... | 29,358,561 | [['C01.221.250.875.049', 'C01.221.812.640.400.070', 'C01.778.640.400.070', 'C01.925.782.815.616.400.049', 'C01.925.813.400.070', 'C10.228.140.380.070', 'C20.673.480.070', 'F03.615.400.050'], ['M01.060.116'], ['G05.360.340.024.340.030'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C2... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Adjuvant regional arterial port chemotherapy after resection of colorectal liver metastases]. | Between 1986 and 1995 we performed radical hepatic resections (R0 resections) in 109 patients with hepatic metastases following colorectal carcinoma. In 50 patients a hepatic arterial port device was implanted for adjuvant regional chemotherapy (HAI). Mitomycin C, 5-fluorouracil, and since 1993 folinic acid have been a... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Combined Chemotherapy Protocols', 'Catheters, Indwelling', 'Chemotherapy, Adjuvant', 'Colorectal Neoplasms', 'Combined Modality Therapy', 'Female', 'Fluorouracil', 'Humans', 'Infusions, Intra-Arterial', 'Leucovorin', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Mitom... | 9,738,219 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E07.132.500'], ['E02.186.170', 'E02.319.170'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bacterial consortium proteomics under 4-chlorosalicylate carbon-limiting conditions. | In this study, the stable consortium composed by Pseudomonas reinekei strain MT1 and Achromobacter xylosoxidans strain MT3 (cell numbers in proportion 9:1) was under investigation to reveal bacterial interactions that take place under severe nutrient-limiting conditions. The analysis of steady states in continuous cult... | ['Achromobacter denitrificans', 'Bacterial Outer Membrane Proteins', 'Bacterial Proteins', 'Catechol 1,2-Dioxygenase', 'Hydrolases', 'Ketol-Acid Reductoisomerase', 'Metabolic Networks and Pathways', 'Metabolome', 'Mixed Function Oxygenases', 'Oxidative Stress', 'Peptide Elongation Factors', 'Proteome', 'Pseudomonas', '... | 19,382,143 | [['B03.440.400.425.115.030.120', 'B03.660.075.090.344.030.120'], ['D12.776.097.120', 'D12.776.543.100'], ['D12.776.097'], ['D08.811.682.690.416.277'], ['D08.811.277'], ['D08.811.682.047.820.487'], ['G03.493'], ['G03.500'], ['D08.811.682.690.708'], ['G03.673', 'G07.775.750'], ['D12.776.835.700'], ['D12.776.817'], ['B03.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Chromium and atherosclerosis]. | The authors report numerous experimental and clinical studies relating deficiency of chromium in the organism and atherosclerosis. They hope new researches to compute the pool of chromium in the organism and the validity and possibility to utilize this oligoelement in prevention of atherosclerosis. | ['Animals', 'Arteriosclerosis', 'Chromium', 'Humans', 'Insulin', 'Lipids'] | 3,537,981 | [['B01.050'], ['C14.907.137.126'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D10']] | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Results of facial nerve decompression. | To evaluate the benefit of facial nerve decompression for Bell's palsy and Hunt's syndrome, prognoses of patients who underwent surgery were compared with those of patients treated conservatively. Facial nerve decompression was slightly effective only in the Bell's palsy patients having 95-100% maximal nerve degenerati... | ['Electrodiagnosis', 'Facial Muscles', 'Facial Nerve', 'Facial Paralysis', 'Humans', 'Movement', 'Myoclonic Cerebellar Dyssynergia', 'Nerve Degeneration', 'Prognosis'] | 3,166,576 | [['E01.370.405'], ['A02.633.567.400', 'A14.363'], ['A08.800.050.050.275', 'A08.800.050.600.149', 'A08.800.800.060.275', 'A08.800.800.120.250'], ['C07.465.327', 'C10.597.622.214', 'C23.888.592.636.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410'], ['C10.228.140.252.700.250', 'C10.228.854... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Health symptoms in relation to temperature, humidity, and self-reported perceptions of climate in New York City residential environments. | Little monitoring has been conducted of temperature and humidity inside homes despite the fact that these conditions may be relevant to health outcomes. Previous studies have observed associations between self-reported perceptions of the indoor environment and health. Here, we investigate associations between measured ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Health Status', 'Heat Stress Disorders', 'Housing', 'Humans', 'Humidity', 'Microclimate', 'Middle Aged', 'New York City', 'Perception', 'Respiratory Tract Infections', 'Seasons', 'Self Report', 'Sleep', 'Symptom Assessment', 'Temperature... | 28,108,783 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['C26.522'], ['J03.340', 'N01.224.791.400', 'N06.230.150.360', 'N06.850.505.400.800.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G16.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, a... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Effects of sodium intake on lactation and Na levels in body fluids of Blackface ewes. | 1. A low-sodium diet was given to Blackface ewes over two reproductive seasons; the diet provided 3-7 mmol Na daily, except for the period of lactation, when Na intake was increased to around 11 mmol/d. The diet of the control ewes was supplemented with sodium chloride to provide the recommended allowance of about ten ... | ['Animals', 'Body Fluids', 'Female', 'Lactation', 'Milk', 'Osmolar Concentration', 'Potassium', 'Pregnancy', 'Sheep', 'Sodium', 'Sodium, Dietary'] | 3,676,195 | [['B01.050'], ['A12.207'], ['G08.686.523', 'G08.686.702.500'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525'], ['G02.640'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['G08.686.784.769'], ['B01.050.150.900.649.313.500.380.791'], ... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Therapeutic response of rosacea to dobesilate. | Despite an incomplete understanding of the pathogenesis of rosacea, therapeutic modalities continue to expand. The principal subtype of rosacea includes erythematotelangiestatic rosacea, which is characterized by uncontrolled angiogenesis. Angiogenic growth factors such as fibroblast growth factors (FGF) and vascular e... | ['Administration, Topical', 'Adult', 'Angiogenesis Inhibitors', 'Calcium Dobesilate', 'Female', 'Fibroblast Growth Factors', 'Humans', 'Ointments', 'Rosacea'] | 16,287,608 | [['E02.319.267.120'], ['M01.060.116'], ['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['D02.455.426.559.389.097.120', 'D02.886.645.600.080.050.100.075'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.255.640'], ['C17.800.716... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Folate and vitamin B6 rapidly normalize endothelial dysfunction in children with type 1 diabetes mellitus. | BACKGROUND: Endothelial dysfunction, a precursor of vascular disease, begins early in type 1 diabetes mellitus and is associated with folate status.METHODS: A randomized, double-blind, placebo-controlled study of folate (5 mg daily) and vitamin B6 (100 mg daily) in 124 children with type 1 diabetes determined the immed... | ['Adolescent', 'Brachial Artery', 'Child', 'Diabetes Mellitus, Type 1', 'Double-Blind Method', 'Endothelium, Vascular', 'Female', 'Folic Acid', 'Hematinics', 'Humans', 'Male', 'Multivariate Analysis', 'Regional Blood Flow', 'Research Design', 'Ultrasonography', 'Vitamin B 6', 'Vitamin B Complex'] | 16,818,571 | [['M01.060.057'], ['A07.015.114.139'], ['M01.060.406'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['A07.015.700.500', 'A10.272.491.355'], ['D03.633.100.733.631.400'], ['D27.505.954.502.543'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[Accuracy of three-step diagnosis in discriminating subtypes of acute ischemic stroke]. | The aim of this study is to evaluate the accuracy of three-step diagnosis in discriminating subtypes of acute ischemic stroke. A total of 120 consecutive patients with first-ever ischemic stroke, admitted to one general hospital, were prospectively studied. In the first step (within 24 hours of clinical onset), the fir... | ['Adult', 'Aged', 'Aged, 80 and over', 'Brain Ischemia', 'Cerebral Infarction', 'Female', 'Humans', 'Male', 'Middle Aged'] | 9,146,068 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300.150', 'C14.907.253.092'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['B01.050.150.900.649.313.988.400.112.40... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Alkaloid analysis by high-performance liquid chromatography-solid phase extraction-nuclear magnetic resonance: new strategies going beyond the standard. | The hyphenated technique HPLC-SPE-NMR is an important tool for rapid dereplication of complex mixtures of in particular small molecules and has been successfully employed in natural product research. However, positively charged alkaloids at low pH are often poorly trapped on the generally used SPE cartridge limiting th... | ['Alkaloids', 'Chromatography, High Pressure Liquid', 'Huperzia', 'Magnetic Resonance Spectroscopy', 'Menispermaceae', 'Plant Extracts', 'Solid Phase Extraction'] | 23,195,707 | [['D03.132'], ['E05.196.181.400.300'], ['B01.650.940.800.575.525.333'], ['E05.196.867.519'], ['B01.650.940.800.575.912.250.725'], ['D20.215.784.500', 'D26.667'], ['E05.196.155.800']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid determination of trans-resveratrol in red wine by solid-phase microextraction with on-fiber derivatization and multidimensional gas chromatography-mass spectrometry. | There has been considerable public interest and a growing number of scientific studies linking certain phenolic compounds in grapes and wines, particularly trans-resveratrol (trans-3,5,4'-trihydroxystilbene, TRA), to human health benefits. Typical TRA concentrations in wine are very low. It is a polar compound with ver... | ['Gas Chromatography-Mass Spectrometry', 'Linear Models', 'Reproducibility of Results', 'Resveratrol', 'Sensitivity and Specificity', 'Solid Phase Microextraction', 'Stereoisomerism', 'Stilbenes', 'Temperature', 'Time Factors', 'Wine'] | 19,081,100 | [['E05.196.181.349.500', 'E05.196.566.500'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['D02.455.426.559.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Directed evolution of an extremely stable fluorescent protein. | In this paper we describe the evolution of eCGP123, an extremely stable green fluorescent protein based on a previously described fluorescent protein created by consensus engineering (CGP: consensus green protein). eCGP123 could not be denatured by a standard thermal melt, preserved almost full fluorescence after overn... | ['Amino Acid Sequence', 'Base Sequence', 'Evolution, Molecular', 'Green Fluorescent Proteins', 'Molecular Sequence Data', 'Mutation', 'Protein Engineering', 'Sequence Analysis, DNA', 'Temperature'] | 19,364,809 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045.250', 'G16.075.250'], ['D12.776.532.265'], ['L01.453.245.667'], ['G05.365.590'], ['E05.393.420.601'], ['E05.393.760.700'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
DNA analysis cervical and vaginal cancer cells during radiotherapy by rapid high-resolution cytometry. | The DNA content of the nuclei of cancer cells of 12 cases of cervical cancer and 2 cases of vaginal cancer, treated with radiotherapy, were studied in 50 specimens. Specimens were taken from each case before radiotherapy and at the totals of 1,000 rad, 2,000 rad, 3,000 rad and 4,500 rad (or 5,000 rad). All specimens we... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Squamous Cell', 'DNA, Neoplasm', 'Dose-Response Relationship, Radiation', 'Female', 'Flow Cytometry', 'Humans', 'Middle Aged', 'Predictive Value of Tests', 'Radiotherapy Dosage', 'Uterine Cervical Neoplasms', 'Vaginal Neoplasms'] | 3,385,280 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D13.444.308.425'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Clonal analysis of CD4+ T helper cell subsets that induce the monocyte procoagulant response. | Monocyte procoagulant inducing factor (MPIF) is a T helper cell-derived cytokine that may play a collaborative role in the expression of cell-mediated immune responses. We have attempted to elucidate whether there is a relationship between MPIF-producing T cell clones and currently proposed subsets of murine T helper c... | ['Animals', 'Biological Factors', 'Blood Coagulation Factors', 'CD4-Positive T-Lymphocytes', 'Cells, Cultured', 'Clone Cells', 'Concanavalin A', 'Cytokines', 'Immunity, Cellular', 'In Vitro Techniques', 'Interleukin-2', 'Interleukin-4', 'Mice', 'Mice, Inbred Strains', 'T-Lymphocytes, Helper-Inducer', 'Time Factors'] | 1,971,532 | [['B01.050'], ['D23'], ['D12.776.124.125', 'D23.119'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.251'], ['A11.251.353'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G12.450.050.400'], ['E05.481'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The role of geriatric assessment units in caring for the elderly: an analytic review. | Specialized geriatric assessment units (GAUs) have been established across North America in response to the growing recognition of the many unmet needs of the frail elderly and the conviction that GAUs can have major beneficial impacts. Although their structures and objectives vary considerably, GAUs are generally desi... | ['Aged', 'Geriatrics', 'Health Facilities', 'Health Status', 'Hospital Units', 'Humans', 'North America', 'Patient Care Team'] | 7,096,923 | [['M01.060.116.100'], ['H02.403.355'], ['N02.278'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['N02.278.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567'], ['N04.590.715']] | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Adherence of staphylococcus aureus to influenza A virus-infected Madin-Darby canine kidney cell cultures. | Madin-Darby canine kidney cells infected with influenza A virus (strains PR8, FM1, Jap 305, and Tex 1) were tested with nine strains of Staphylococcus aureus and group B Streptococcus type Ic to determine whether mammalian cells become susceptible to bacterial adherence as a result of virus infection. Bacterial adheren... | ['Adhesiveness', 'Animals', 'Binding Sites', 'Cells, Cultured', 'Dogs', 'Influenza A virus', 'Kidney', 'Orthomyxoviridae Infections', 'Radioimmunoassay', 'Staphylococcus aureus', 'Temperature', 'Time Factors', 'Trypsin'] | 7,216,481 | [['G02.860.139'], ['B01.050'], ['G02.111.570.120'], ['A11.251'], ['B01.050.150.900.649.313.750.250.216.200'], ['B04.820.480.968.405.400'], ['A05.810.453'], ['C01.925.782.620'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.510.100.750.750.100'... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Statistical models and time series forecasting of sulfur dioxide: a case study Tehran. | This study performed a time-series analysis, frequency distribution and prediction of SO(2) levels for five stations (Pardisan, Vila, Azadi, Gholhak and Bahman) in Tehran for the period of 2000-2005. Most sites show a quite similar characteristic with highest pollution in autumn-winter time and least pollution in sprin... | ['Air Pollutants', 'Environmental Monitoring', 'Forecasting', 'Iran', 'Models, Statistical', 'Sulfur Dioxide'] | 18,612,833 | [['D27.888.284.101'], ['N06.850.460.350.080', 'N06.850.780.375'], ['I01.320'], ['Z01.252.245.500.350'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['D01.362.810', 'D01.650.550.850.925', 'D01.875.825.925']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Kinetics of P-glycoprotein-mediated efflux of paclitaxel. | Paclitaxel is a substrate of the mdr1 P-glycoprotein (Pgp). The objective of the present study was to determine the kinetics of the Pgp-mediated efflux and its contribution to the overall efflux of paclitaxel at the clinically achievable concentration range of 1 to 1500 nM. Human breast carcinoma BC19 cells that were d... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Algorithms', 'Antineoplastic Agents, Phytogenic', 'Breast Neoplasms', 'Female', 'Genes, MDR', 'Humans', 'Models, Biological', 'Paclitaxel', 'Reproducibility of Results', 'Transfection', 'Tumor Cells, Cultured'] | 11,504,826 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['G17.035', 'L01.224.050'], ['D27.505.954.248.179'], ['C04.588.180', 'C17.800.090.500'], ['G05.360.340.024.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Age differences in hostility among middle-aged and older adults. | Multiple measures of hostility were administered to middle-aged and older volunteers. There was a positive association between age and self-report measures reflecting hostile beliefs about others, including cynicism and suspiciousness. There was a weak inverse relationship between age and self-report measures of the ov... | ['Adult', 'Aged', 'Aging', 'Anger', 'Female', 'Gender Identity', 'Hostility', 'Humans', 'Interpersonal Relations', 'Irritable Mood', 'Male', 'Middle Aged', 'Personality Assessment'] | 8,461,112 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['F01.470.093'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['F01.470.596'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F01.470.047.110'], ['M01.060.116.630'], ['F04.513']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Infectious clone construction of dengue virus type 2, strain Jamaican 1409, and characterization of a conditional E6 mutation. | A full-length infectious cDNA clone (ic) was constructed from the genome of the dengue virus type 2 (DENV-2) Jamaica83 1409 strain, pBAC1409ic, by using a bacterial artifical chromosome plasmid system. Infectious virus was generated and characterized for growth in cell culture and for infection in Aedes aegypti mosquit... | ['Aedes', 'Amino Acid Substitution', 'Animals', 'Cell Line', 'Chromosomes, Artificial, Bacterial', 'Cloning, Molecular', 'DNA, Complementary', 'DNA, Viral', 'Dengue Virus', 'Genome, Viral', 'Giant Cells', 'Macaca mulatta', 'Mutation', 'RNA, Viral', 'Sequence Analysis, DNA', 'Transfection', 'Viral Envelope Proteins'] | 16,847,122 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['A11.251.210'], ['A11.284.187.178.170', 'A11.284.187.190.170', 'A20.812.170', 'G05.360.162.178.170', 'G05.360.162.190.170', 'G05.360.337.249.170'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.50... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long noncoding RNA Gm6135 functions as a competitive endogenous RNA to regulate toll-like receptor 4 expression by sponging miR-203-3p in diabetic nephropathy. | We aim to explore the relationship between Gm6135 and diabetic nephropathy. We detected the relative expression levels of Gm6135 and toll-like receptor 4 (TLR4) in diabetic nephropathy mice and high-glucose-cultured mouse mesangial cells SV40-MES-13 by the quantitative reverse transcription-polymerase chain reaction (q... | ['Animals', 'Apoptosis', 'Cell Line, Tumor', 'Cell Proliferation', 'Diabetic Nephropathies', 'Down-Regulation', 'Kidney', 'Mesangial Cells', 'Mice', 'MicroRNAs', 'RNA, Long Noncoding', 'RNA, Small Interfering', 'Toll-Like Receptor 4'] | 30,295,314 | [['B01.050'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C12.777.419.192', 'C13.351.968.419.192', 'C19.246.099.875'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['A05.810.453'], ['A05.810.453.324.359.620', 'A05.810.453.736.520.620', 'A11.329.228.950'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chronic administration of amiodarone and thyroid function: a follow-up study. | In order to evaluate the effects of amiodarone on thyroid function in chronically treated patients, 43 consecutive patients, who had been taking a mean weekly dose of 1420 +/- 488 mg for more than 9 months (mean 16.5 months), were studied. In a first evaluation, three patients with hypothyroidism and two with hyperthyr... | ['Adult', 'Aged', 'Amiodarone', 'Benzofurans', 'Chronic Disease', 'Coronary Disease', 'Female', 'Follow-Up Studies', 'Goiter', 'Heart Failure', 'Heart Valve Diseases', 'Humans', 'Hyperthyroidism', 'Hypothyroidism', 'Male', 'Middle Aged', 'Thyroid Function Tests', 'Thyroid Gland'] | 6,496,285 | [['M01.060.116'], ['M01.060.116.100'], ['D03.633.100.127.075'], ['D03.633.100.127'], ['C23.550.291.500'], ['C14.280.647.250', 'C14.907.585.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C19.874.283'], ['C14.280.434'], ['C14.280.484'], ['B01.050.150.900.649.313.988.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Glutamine synthetase regulation, adenylylation state, and strain specificity analyzed by polyacrylamide gel electrophoresis. | We used polyacrylamide gel electrophoresis to examine the regulation and adenylylation states of glutamine synthetases (GSs) from Escherichia coli (GS(E)) and Klebsiella aerogenes (GS(K)). In gels containing sodium dodecyl sulfate (SDS), we found that GS(K) had a mobility which differed significantly from that of GS(E)... | ['Adenosine Monophosphate', 'Alleles', 'Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Glutamate-Ammonia Ligase', 'Klebsiella pneumoniae', 'Mutation', 'Species Specificity'] | 33,958 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Non-invasive urodynamic approach to the diagnosis, treatment and follow-up of voiding disorders in pediatric patients]. | The authors reports their experience on 248 patients affected by minctional disorders isolated or related to UTI (upper tract infections) and VUR (vesico-ureteral reflux). All the patients were assessed throught a predominantly non invasive diagnostic approach which included: pediatric urologic examination with aimed a... | ['Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Urinary Retention', 'Urinary Tract Infections', 'Urodynamics', 'Vesico-Ureteral Reflux'] | 12,916,438 | [['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.934.880', 'C13.351.968.934.880'], ['C01.915', 'C12.777.892', 'C13.351.968.892'], ['G08.852.898'], ['C12.777.829.920', 'C13.351.968.829.920']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Pharmacological evaluation of Mongolian medicine Syringa pinnatifolia fraction I against acute myocardial ischemia in mice]. | Syringa pinnatifolia Hemsl.( SP) is a representative Mongolian folk medicine with the effects of inhibiting Heyi related diseases,clearing heat and relieving pain. It has been used for the treatment of Heyi-induced heart tingling,heart palpitations,upset,insomnia and other symptoms. Total ethanol extract( T) and major ... | ['Animals', 'Cyclooxygenase 1', 'Cyclooxygenase 2', 'Heart', 'Medicine, Mongolian Traditional', 'Membrane Proteins', 'Mice', 'Myocardial Ischemia', 'Myocardium', 'Plant Extracts', 'Syringa', 'Tumor Suppressor Protein p53'] | 32,237,363 | [['B01.050'], ['D08.811.600.720.500'], ['D08.811.600.720.750'], ['A07.541'], ['E02.190.488.585.850', 'I01.076.201.450.654.558.750'], ['D12.776.543'], ['B01.050.150.900.649.313.992.635.505.500'], ['C14.280.647', 'C14.907.585'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D20.215.784.500', 'D26.667'], ['B01.650.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
The neural basis of motivational influences on cognitive control. | Cognitive control mechanisms support the deliberate regulation of thought and behavior based on current goals. Recent work suggests that motivational incentives improve cognitive control and has begun to elucidate critical neural substrates. We conducted a quantitative meta-analysis of neuroimaging studies of motivated... | ['Brain', 'Executive Function', 'Functional Neuroimaging', 'Humans', 'Motivation', 'Nerve Net', 'Reward'] | 30,120,846 | [['A08.186.211'], ['F02.463.217'], ['E01.370.350.578.875', 'E01.370.376.537.625', 'E05.629.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['A08.511'], ['F02.463.425.770.836']] | ['Anatomy [A]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19 : A Randomized Trial. | BACKGROUND: No effective oral therapy exists for early coronavirus disease 2019 (COVID-19).OBJECTIVE: To investigate whether hydroxychloroquine could reduce COVID-19 severity in adult outpatients.DESIGN: Randomized, double-blind, placebo-controlled trial conducted from 22 March through 20 May 2020. (ClinicalTrials.gov:... | ['Adult', 'Antimalarials', 'Betacoronavirus', 'COVID-19', 'Coronavirus Infections', 'Double-Blind Method', 'Female', 'Follow-Up Studies', 'Humans', 'Hydroxychloroquine', 'Male', 'Middle Aged', 'Outpatients', 'Pandemics', 'Pneumonia, Viral', 'Retrospective Studies', 'Risk Factors', 'SARS-CoV-2', 'Time Factors'] | 32,673,060 | [['M01.060.116'], ['D27.505.954.122.250.100.085'], ['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['C01.925.782.600.550.200'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Progesterone and caspase-3 activation in equine cyclic corpora lutea. | Soon after ovulation, the newly formed corpus luteum (CL) starts secreting progesterone (P(4)), necessary for implantation. The CL, an ovarian transient endocrine organ, undergoes growth and regression throughout its life span. The objective of this study was to evaluate if caspase-3 mediates cell death in the equine c... | ['Animals', 'Caspase 3', 'Corpus Luteum', 'Estrous Cycle', 'Female', 'Horses', 'Immunohistochemistry', 'Progesterone'] | 17,635,775 | [['B01.050'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['A05.360.319.114.630.278', 'A06.300.312.497.278'], ['G08.686.195'], ['B01.050.150.900.649.313.984.235.472'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A European survey on public health policies for managing cases of meningococcal disease and their contacts. | In 2007, a European survey was conducted to compare national policies on public health management of cases of meningococcal disease and their contacts. The results revealed differences in definitions of close contacts and prophylactic regimens between countries. These differences can be attributed to a lack of evidence... | ['Contact Tracing', 'Disease Notification', 'Disease Outbreaks', 'Europe', 'Health Care Surveys', 'Health Policy', 'Humans', 'Meningococcal Infections', 'Population Surveillance'] | 18,445,439 | [['E05.318.270', 'N06.850.520.270', 'N06.850.780.200.225'], ['E05.318.362', 'N06.850.520.373', 'N06.850.780.200.262'], ['N06.850.290'], ['Z01.542'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.62... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Evidence for a downward secular trend in age of menarche in a rural Gambian population. | Menarcheal age is a key indicator of female maturity and development. Studies in many countries have reported a downward secular trend in age of menarche over the past century. This study presents data gained using the 'status quo' method and interval regression to estimate median menarcheal age of girls in a rural Gam... | ['Adolescent', 'African Continental Ancestry Group', 'Age Distribution', 'Child', 'Cross-Sectional Studies', 'Female', 'Gambia', 'Humans', 'Menarche', 'Reproductive History', 'Rural Population', 'Socioeconomic Factors', 'Young Adult'] | 20,465,526 | [['M01.060.057'], ['M01.686.508.100'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.406'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['Z01.058.290.190.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.760.410', 'G08.686.841.374.410'], ['E01.370.51... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Clinical features of sporadic Campylobacter infections in Norway. | To assess risk factors and clinical impact of campylobacteriosis in Norway, a case-control study of sporadic cases of infection with thermotolerant Campylobacter spp. was conducted. This report describes: (1) the frequency and duration of signs and symptoms, antimicrobial treatment, hospitalization, and faecal carriage... | ['Abdominal Pain', 'Adolescent', 'Adult', 'Aged', 'Anti-Infective Agents', 'Campylobacter Infections', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Diarrhea', 'Feces', 'Female', 'Fever', 'Hospitalization', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Norway', 'Travel'] | 1,287,808 | [['C23.888.592.612.054', 'C23.888.821.030'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122'], ['C01.150.252.400.177'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['C23.888.821.214'], ['A12.459'], ['C23.888.119.344'], ['... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Plasmin-mediated activation of pandemic H1N1 influenza virus hemagglutinin is independent of the viral neuraminidase. | Influenza virus is well recognized to modulate host tropism and pathogenesis based on mutations in the proteolytic cleavage site of the viral hemagglutinin (HA), which activates HA and exposes the fusion peptide for membrane fusion. Instead of the conventional trypsin-mediated cleavage event, modification of the cleava... | ['Amino Acid Sequence', 'Animals', 'Fibrinolysin', 'Hemagglutinin Glycoproteins, Influenza Virus', 'Humans', 'Influenza A Virus, H1N1 Subtype', 'Influenza, Human', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Molecular Sequence Data', 'Neuraminidase', 'Pandemics', 'Protein Processing, Post-Translational', 'Sequence Alignmen... | 23,449,787 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D08.811.277.656.300.760.330', 'D08.811.277.656.959.350.330'], ['D12.776.964.970.880.345.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.405.400.214'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['B01.050.150.900.649.313.99... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Evaluating distance functions for clustering tandem repeats. | Tandem repeats are an important class of DNA repeats and much research has focused on their efficient identification, their use in DNA typing and fingerprinting, and their causative role in trinucleotide repeat diseases such as Huntington Disease, myotonic dystrophy, and Fragile-X mental retardation. We are interested ... | ['Algorithms', 'Base Sequence', 'Chromosome Mapping', 'Cluster Analysis', 'Computational Biology', 'Consensus Sequence', 'Entropy', 'Humans', 'Reproducibility of Results', 'Sequence Homology, Nucleic Acid', 'Tandem Repeat Sequences'] | 16,362,901 | [['G17.035', 'L01.224.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.183'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['H01.158.273.180', 'L01.313.124'], ['G02.111.570.580.175'], ['G01.906.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.725', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Polycationic peptide guided spherical ordered self-assembly of biomacromolecules. | Achieving effective controllable delivery of therapeutic biomacromolecules for long action without new molecular entities generation or carriers employed offers a promising alternative and significant clinical benefit. We show here that recombinant human interferon-alpha (rhIFN) can form a three dimensional ordered str... | ['Circular Dichroism', 'Enzyme-Linked Immunosorbent Assay', 'Humans', 'Interferon-alpha', 'Peptides', 'Polyamines', 'Polyelectrolytes', 'Recombinant Proteins', 'X-Ray Diffraction'] | 22,958,981 | [['E05.196.867.151'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890.250', 'D12.776.467.374.440.890.250', 'D23.529.374.440.890.250'], ['D12.644'], ['D02.092.782'], ['D01.248.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predictive Factor of Conversion to Laparotomy in Minimally Invasive Surgical Staging for Endometrial Cancer. | OBJECTIVE: The aim of the study was to identify risk factors associated with laparotomy conversion during total laparoscopic hysterectomy for endometrial cancer.METHODS: This is a retrospective study examining endometrial cancer cases that underwent hysterectomy-based surgical staging initiated via conventional laparos... | ['Adult', 'Aged', 'Conversion to Open Surgery', 'Endometrial Neoplasms', 'Endometrium', 'Female', 'Humans', 'Laparotomy', 'Middle Aged', 'Neoplasm Staging', 'Retrospective Studies'] | 26,569,058 | [['M01.060.116'], ['M01.060.116.100'], ['E04.502.250.155'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['A05.360.319.679.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.406'], ['M01.060.116.630'], ['E01.789.625'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
West Nile virus infection in a sun conure (Aratinga solstitialis). | A 2-year-old sun conure (Aratinga solstitialis) was examined because of acute lethargy and depression. Physical examination revealed severe weakness with ventroflexion of the head and neck and seizure episodes precipitated by handling. Empirical and supportive care was instituted, and serial diagnostic testing revealed... | ['Animals', 'Bird Diseases', 'Cerebrum', 'Psittaciformes', 'West Nile Fever', 'West Nile virus'] | 19,014,098 | [['B01.050'], ['C22.131'], ['A08.186.211.200.885.287'], ['B01.050.150.900.248.710'], ['C01.207.245.340.300.887', 'C01.207.399.750.300.887', 'C01.920.500.343.950', 'C01.925.081.343.950', 'C01.925.182.525.300.850', 'C01.925.782.310.950', 'C01.925.782.350.250.900', 'C10.228.140.430.520.750.300.887', 'C10.228.228.245.340.3... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Abnormalities of growth in 7- to 18-year-old psychiatric patients. | The growth curves of all nonimmigrant school-age children living in one district of Malm?, Sweden and treated at the Department of Child and Youth Psychiatry during 1983 were investigated. The study group consisted of 40 children. Twenty-five of these children (63%) showed abnormal growth compared to 6 children (15%) w... | ['Adolescent', 'Child', 'Female', 'Food', 'Growth Disorders', 'Humans', 'Male', 'Mental Disorders', 'Psychotic Disorders'] | 2,925,582 | [['M01.060.057'], ['M01.060.406'], ['G07.203.300', 'J02.500'], ['C23.550.393'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['F03.700.675']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Minute lesions of esophageal cancer. | Fifty-four cases of minute esophageal cancer (1 cm or less in the greatest dimension) were collected and analyzed. Of these 67% were mucosal cancer and 28% were submucosal cancer. Prognosis was anticipated to be good as there was only one case of lymph node metastasis and three of vascular invasion. A lesion of 1 cm ca... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Squamous Cell', 'Esophageal Neoplasms', 'Esophagoscopy', 'Female', 'Humans', 'Male', 'Middle Aged'] | 3,451,335 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['E01.370.372.250.250.275', 'E01.370.388.250.250.250.260', 'E04.210.240.250.260', 'E04.502.250.250.250.260'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A mechanistic individual-based model of the feeding processes for Oikopleura dioica. | A mechanistic physiological model of the appendicularian Oikopleura dioica has been built to represent its three feeding processes (filtration, ingestion and assimilation). The mathematical formulation of these processes is based on laboratory observations from the literature, and tests different hypotheses. This model... | ['Animals', 'Computer Simulation', 'Eating', 'Feces', 'Feeding Behavior', 'Food', 'Intestinal Absorption', 'Models, Biological', 'Urochordata'] | 24,223,782 | [['B01.050'], ['L01.224.160'], ['G07.203.650.283', 'G10.261.330'], ['A12.459'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['G07.203.300', 'J02.500'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500', 'G07.690.725.015.500.374.500', 'G10.261.353.500'], ['E05.599.395'], ['B01.050.150.2... | ['Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Lasy-Seq: a high-throughput library preparation method for RNA-Seq and its application in the analysis of plant responses to fluctuating temperatures. | RNA-Seq is a whole-transcriptome analysis method used to research biological mechanisms and functions but its use in large-scale experiments is limited by its high cost and labour requirements. In this study, we have established a high-throughput and cost-effective RNA-Seq library preparation method that does not requi... | ['Adaptation, Physiological', 'Arabidopsis', 'DNA, Plant', 'Gene Library', 'Polymerase Chain Reaction', 'RNA, Messenger', 'RNA, Plant', 'RNA, Ribosomal', 'RNA-Seq', 'Reverse Transcription', 'Temperature', 'Transcriptome'] | 31,068,632 | [['G07.025', 'G16.012.500'], ['B01.650.940.800.575.912.250.157.100'], ['D13.444.308.435'], ['G05.360.325'], ['E05.393.620.500'], ['D13.444.735.544'], ['D13.444.735.635'], ['D13.444.735.686'], ['E05.393.332.250', 'E05.393.760.319.500', 'E05.393.760.710.500'], ['G02.111.873.500', 'G05.297.700.500'], ['G01.906.595', 'G16.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The state of infant oral healthcare knowledge and awareness: disparity among parents and healthcare professionals. | Provision of infant oral health (IOH) care is a challenging issue in the rural areas of our country due to lack of pedodontists and other dental workforces. To overcome these barriers it is essential to call the medical and other healthcare professionals to provide IOH care in joint collaboration with dental profession... | ['Attitude of Health Personnel', 'Cross-Sectional Studies', 'Dental Care for Children', 'Health Knowledge, Attitudes, Practice', 'Humans', 'India', 'Infant', 'Minority Groups', 'Parents', 'Pediatric Dentistry', 'Preventive Dentistry', 'Rural Population', 'Students, Dental', 'Students, Medical', 'Surveys and Questionnai... | 19,414,973 | [['F01.100.050', 'N05.300.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E06.170.152', 'N02.421.240.190.215'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['M01.060.703'], ['I01.880.853.300'], ['F01.829.263.500.32... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Prevalence of crowded optic discs in adult Chinese. The Beijing Eye Study. | BACKGROUND: To determine the prevalence of crowded optic discs and their associations with ocular and general parameters.METHODS: The Beijing Eye Study included 4,439 subjects out of 5,324 subjects invited to participate (response rate 83.4%) with an age of 40+ years. The present investigation consisted of 8,594 eyes (... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Asian Continental Ancestry Group', 'China', 'Eye Abnormalities', 'Female', 'Humans', 'Intraocular Pressure', 'Male', 'Middle Aged', 'Optic Disk', 'Prevalence', 'Visual Acuity', 'Visual Fields'] | 18,389,273 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.686.508.200'], ['Z01.252.474.164'], ['C11.250', 'C16.131.384'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['M01.060.116.630'], ['A08.800.800.120.680.660', 'A09.371.729.690'], ['E05.318.308.9... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Retrieval of intraperitoneal Penrose drain under transvaginal endoscopic guidance. | BACKGROUND: One of the unfortunate complications associated with the use of Penrose drains is slipping down of the drain into the peritoneal cavity because of incomplete placement of skin sutures to secure the drain.CASE: A 49-year-old woman with the International Federation of Gynecology and Obstetrics (FIGO) stage II... | ['Drainage', 'Endoscopy', 'Female', 'Foreign Bodies', 'Humans', 'Hysterectomy', 'Middle Aged', 'Ovarian Neoplasms', 'Ovariectomy'] | 16,542,713 | [['E02.309', 'E04.237'], ['E01.370.388.250', 'E04.502.250'], ['C26.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['M01.060.116.630'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.630.705'], ['E04.270.282.685', 'E04.950.165.685', 'E04.950.30... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A mechanistic investigation of the EDWARDS INTUITY Elite valve's hemodynamic performance. | OBJECTIVE: Rapid deployment surgical aortic valve replacement has emerged as an alternative to the contemporary sutured valve technique. A difference in transvalvular pressure has been observed clinically between RD-SAVR and contemporary SAVR. A mechanistic inquiry into the impact of the rapid deployment valve inflow f... | ['Aortic Valve', 'Aortic Valve Stenosis', 'Bioprosthesis', 'Heart Valve Prosthesis', 'Heart Valve Prosthesis Implantation', 'Hemodynamics', 'Humans', 'Prosthesis Design', 'X-Ray Microtomography'] | 31,250,203 | [['A07.541.510.110'], ['C14.280.484.048.750', 'C14.280.955.249'], ['E07.695.100'], ['E07.695.310'], ['E04.100.376.485', 'E04.650.410', 'E04.928.220.410'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.320.550', 'E07.695.680'], ['E01.370.350.700.810.810.900', 'E01.370.350.825.810.810.900']] | ['Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The coated vesicle vacuolar (H+)-ATPase associates with and is phosphorylated by the 50-kDa polypeptide of the clathrin assembly protein AP-2. | We have previously noted a 50-kDa polypeptide (p50) co-purifying with preparations of the bovine brain clathrin-coated vesicle vacuolar (H+)-ATPase (V-ATPase) (Zhang, J., Myers, M., and Forgac, M. (1992) J. Biol. Chem. 267, 9773-9778). We show that p50 is also immunoprecipitated with the V-ATPase, further suggesting it... | ['Adaptor Protein Complex 2', 'Adaptor Protein Complex mu Subunits', 'Adaptor Proteins, Vesicular Transport', 'Adenosine Triphosphate', 'Amino Acid Sequence', 'Animals', 'Brain', 'Cattle', 'Chromatography, Affinity', 'Coated Pits, Cell-Membrane', 'Electrophoresis, Polyacrylamide Gel', 'Ethylmaleimide', 'Macromolecular ... | 8,486,617 | [['D12.776.543.990.150.200'], ['D12.776.543.990.150.500.500'], ['D12.776.543.990.150'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A08.186.211'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.181.400.170'], ['A11.284.149... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Evidence for spinal conditioning in intact rats. | Prior work suggests that spinal systems are sensitive to the stimulus relationships that underlie Pavlovian conditioning. We studied this phenomenon in Sprague-Dawley rats by pairing a vibrotactile conditioned stimulus (CS) with a tailshock unconditioned stimulus (US). Experiment 1 showed that spinal rats exhibit diffe... | ['Animals', 'Association Learning', 'Behavior, Animal', 'Conditioning, Classical', 'Male', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley', 'Spinal Cord', 'Stereotaxic Techniques', 'Touch', 'Vibration'] | 9,013,502 | [['B01.050'], ['F02.463.425.069.296'], ['F01.145.113'], ['F02.463.425.179.308'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['A08.186.854'], ['E04.525.800', 'E05.873'], ['F02.830.816.... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
An assessment of stigma and human right violations among men who have sex with men in Abuja, Nigeria. | BACKGROUND: There have been several barriers in effectively engaging men who have sex with men for STI/HIV prevention and treatment programming in Nigeria including social stigma, policies, and laws criminalizing same-sex practices. The objective of this study was to describe the human rights context for MSM in Abuja a... | ['Adult', 'Disclosure', 'HIV Infections', 'Homosexuality, Male', 'Human Rights', 'Humans', 'Male', 'Nigeria', 'Prevalence', 'Risk-Taking', 'Sexual Behavior', 'Sexually Transmitted Diseases', 'Social Stigma', 'Surveys and Questionnaires'] | 30,832,654 | [['M01.060.116'], ['F01.829.401.046', 'I01.880.604.583.080.134', 'L01.143.335'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['F01.145.802.975.500.600', 'G08.686.867.500.600'], ['I01.880.604.473', 'N03.706.437'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Quantitative analysis of Doppler waveform of hepatic veins for assessment of hepatic functional reserve. | BACKGROUND/AIMS: The Doppler waveform of hepatic veins in healthy humans is a triphasic waveform (two negative waves and one positive). Recent studies emphasize the role of Doppler ultrasonography in the evaluation of liver cirrhosis. The analysis of the Doppler waveform of hepatic veins might be a useful and non-invas... | ['Adult', 'Aged', 'Carcinoma, Hepatocellular', 'Female', 'Fibrosis', 'Hepatectomy', 'Hepatic Veins', 'Humans', 'Liver', 'Liver Function Tests', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Necrosis', 'Prospective Studies', 'Pulsatile Flow', 'Ultrasonography, Doppler, Pulsed'] | 17,419,256 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['C23.550.355'], ['E04.210.556'], ['A07.015.908.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['E01.370.372.460'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Distal radius osteotomy with intramedullary fixation for the treatment of Kienbock disease. | Symptomatic Kienbock disease with ulnar-negative variance is commonly treated with a distal radius shortening osteotomy. Traditionally, the osteotomy is stabilized using dorsal or volar plating. Use of an intramedullary implant to stabilize the osteotomy in the treatment of this condition is demonstrated in this articl... | ['Adult', 'Bone Plates', 'Female', 'Follow-Up Studies', 'Fracture Fixation, Intramedullary', 'Humans', 'Internal Fixators', 'Male', 'Middle Aged', 'Osteonecrosis', 'Osteotomy', 'Pain Measurement', 'Radiography', 'Radius', 'Range of Motion, Articular', 'Recovery of Function', 'Risk Assessment', 'Sampling Studies', 'Trea... | 22,913,997 | [['M01.060.116'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.555.300.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.370', 'E07.858.442.660.460', 'E07.858.690.725.460'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sex Differences in Long-Term Mortality After Stroke in the INSTRUCT (INternational STRoke oUtComes sTudy): A Meta-Analysis of Individual Participant Data. | BACKGROUND: Women are reported to have greater mortality after stroke than men, but the reasons are uncertain. We examined sex differences in mortality at 1 and 5 years after stroke and identified factors contributing to these differences.METHODS AND RESULTS: Individual participant data for incident strokes were obtain... | ['Age Factors', 'Aged', 'Australasia', 'Caribbean Region', 'Europe', 'Female', 'Health Status Disparities', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Odds Ratio', 'Prognosis', 'Risk Assessment', 'Risk Factors', 'Severity of Illness Index', 'Sex Factors', 'South America', 'Stroke', 'Time Factors'] | 28,228,454 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['Z01.678.100'], ['Z01.107.084'], ['Z01.542'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.... | ['Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Beauty is in the belief of the beholder: cognitive influences on the neural response to facial attractiveness. | Judgments of facial attractiveness are central to decision-making in various domains, but little is known about the extent to which they are malleable. In this study, we used EEG/ERP methods to examine two novel influences on neural and subjective responses to facial attractiveness: an observer's expectation and repeti... | ['Adolescent', 'Beauty', 'Brain', 'Cognition', 'Decision Making', 'Electroencephalography', 'Evoked Potentials', 'Face', 'Female', 'Humans', 'Judgment', 'Male', 'Self Report', 'Young Adult'] | 27,522,090 | [['M01.060.057'], ['F02.463.785.477.304', 'K01.752.210.304'], ['A08.186.211'], ['F02.463.188'], ['F02.463.785.373'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.785.626'], ['E05.318.308.980.500', 'N05.715.360... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enhanced tolerance to drought and salt stresses in transgenic faba bean (Vicia faba L.) plants by heterologous expression of the PR10a gene from potato. | KEY MESSAGE: We report for the first time that expression of potato PR10a gene in faba bean causes enhanced tolerance to drought and salinity. Grain legumes such as soybean (Glycine max L. Merrill), pea (Pisum sativum L.) and faba bean (Vicia faba L.) are staple sources of protein for human and animal nutrition. Among ... | ['Agrobacterium tumefaciens', 'Droughts', 'Gene Expression Regulation, Plant', 'Hydro-Lyases', 'Plant Proteins', 'Plants, Genetically Modified', 'Promoter Regions, Genetic', 'Salt Tolerance', 'Solanum tuberosum', 'Stress, Physiological', 'Vicia faba'] | 23,455,709 | [['B03.440.400.425.700.024.050', 'B03.660.050.662.024.500'], ['G16.500.175.781', 'G16.500.750.775.154', 'N06.230.100.230.150'], ['G05.308.375'], ['D08.811.520.241.300'], ['D12.776.765'], ['B01.650.520', 'B05.620.600'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['G07.025.133.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Characterization the role of a UFC homolog, AtAuxRP3, in the regulation of Arabidopsis seedling growth and stress response. | Auxin is a well-known, crucial regulator of the entire plant lifecycle, not only orchestrating many aspects of plant growth and development, but also playing various roles in biotic and abiotic stress. This study reports the isolation and functional characterization of a DUF-966 domain-containing gene, At3g46110, re-na... | ['Arabidopsis', 'Arabidopsis Proteins', 'Gene Expression Regulation, Plant', 'Indoleacetic Acids', 'Membrane Proteins', 'Plant Growth Regulators', 'Plants, Genetically Modified', 'Seedlings', 'Signal Transduction'] | 31,207,460 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G05.308.375'], ['D03.066.288', 'D03.633.100.473.404'], ['D12.776.543'], ['D27.505.696.377.760'], ['B01.650.520', 'B05.620.600'], ['A18.550', 'B01.650.819'], ['G02.111.820', 'G04.835']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intermediate fibrosis staging in hepatitis C: a problem not overcome by optimal samples or pathologists' expertise. | BACKGROUND AND AIMS: The prediction of intermediate stage of fibrosis in chronic hepatitis C represents a prognostic factor for disease progression. Studies evaluating biopsy performance in intermediate stage considering current patterns of liver samples and pathologists' variability are scarce. We aimed to evaluate th... | ['Biopsy, Needle', 'Clinical Competence', 'Cross-Sectional Studies', 'Diagnostic Errors', 'Hepatitis C, Chronic', 'Humans', 'Liver', 'Liver Cirrhosis', 'Observer Variation', 'Predictive Value of Tests', 'Reproducibility of Results', 'Severity of Illness Index'] | 26,256,893 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
TESE: generating specific protein structure test set ensembles. | UNLABELLED: TESE is a web server for the generation of test sets of protein sequences and structures fulfilling a number of different criteria. At least three different use cases can be envisaged: (i) benchmarking of novel methods; (ii) test sets tailored for special needs and (iii) extending available datasets. The CA... | ['Computational Biology', 'Databases, Protein', 'Internet', 'Models, Molecular', 'Protein Conformation', 'Proteins'] | 18,796,478 | [['H01.158.273.180', 'L01.313.124'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['L01.224.230.110.500'], ['E05.599.595'], ['G02.111.570.820.709'], ['D12.776']] | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Epidemiology of canine babesiosis in relation to the activity of Dermacentor reticulatus in southern Jura (France). | Dates of onset of canine babesiosis within a hyperendemic focus in France (Rhone Valley, south of Jura and north of the Alps) were compared to the seasonal population level of the adult stage of Dermacentor reticulatus over a 12-month period (December 1982-November 1983). Cases of babesiosis occurred in spring and fall... | ['Animals', 'Arachnid Vectors', 'Babesiosis', 'Dermacentor', 'Dog Diseases', 'Dogs', 'France', 'Seasons'] | 1,893,798 | [['B01.050'], ['N06.850.335.188.100.100', 'N06.850.520.203.375.100.100'], ['C01.610.701.688.122', 'C01.610.752.075', 'C01.610.752.625.122', 'C01.920.930.182', 'C22.674.710.122'], ['B01.050.500.131.166.132.832.400.200'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['Z01.542.286'], ['G01.910.645.661', 'G16.... | ['Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Stochastic simulations of mixed-lipid compartments: from self-assembling vesicles to self-producing protocells. | The computational platform ENVIRONMENT, developed to simulate stochastically reaction systems in varying compartmentalized conditions [Mavelli and Ruiz-Mirazo: Philos Trans R Soc Lond B Biol Sci 362:1789-1802, 2007; Physical Biology 7(3): 036002, 2010], is here applied to study the dynamic properties and stability of m... | ['Algorithms', 'Artificial Cells', 'Computational Biology', 'Computer Simulation', 'Cytoplasmic Vesicles', 'Kinetics', 'Lipids', 'Membrane Lipids', 'Models, Biological', 'Monte Carlo Method', 'Osmosis', 'Permeability', 'Phospholipids', 'Stochastic Processes'] | 21,431,610 | [['G17.035', 'L01.224.050'], ['J01.637.051.479.258', 'J01.637.087.500.254'], ['H01.158.273.180', 'L01.313.124'], ['L01.224.160'], ['A11.284.430.214.190.875.190'], ['G01.374.661', 'G02.111.490'], ['D10'], ['D10.570'], ['E05.599.395'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Medical cost impact of intrathecal baclofen therapy for severe spasticity. | OBJECTIVES: To evaluate the economic effects of intrathecal baclofen (ITB) for patients with severe spasticity based on costs of care before and after implantation of an intrathecal drug delivery system.MATERIALS AND METHODS: An actuarial projection of post-implant experience in the absence of ITB intervention was used... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Baclofen', 'Cost-Benefit Analysis', 'Databases, Factual', 'Drug Delivery Systems', 'Female', 'Health Care Costs', 'Humans', 'Male', 'Middle Aged', 'Muscle Relaxants, Central', 'Muscle Spasticity', 'Retrospective Studies', 'Time Factors', 'Young Adult'] | 25,145,312 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['D02.241.081.114.500.350.100'], ['N03.219.151.125'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E02.319.300'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], [... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Autism spectrum disorder, flea and tick medication, and adjustments for exposure misclassification: the CHARGE (CHildhood Autism Risks from Genetics and Environment) case-control study. | BACKGROUND: The environmental contribution to autism spectrum disorders (ASD) is largely unknown, but household pesticides are receiving increased attention. We examined associations between ASD and maternally-reported use of imidacloprid, a common flea and tick treatment for pets.METHODS: Bayesian logistic models were... | ['Animals', 'Bayes Theorem', 'Bias', 'Case-Control Studies', 'Child Development Disorders, Pervasive', 'Child, Preschool', 'Environmental Exposure', 'Female', 'Humans', 'Imidazoles', 'Logistic Models', 'Male', 'Neonicotinoids', 'Nitro Compounds', 'Odds Ratio', 'Pesticides', 'Pregnancy', 'Prenatal Exposure Delayed Effec... | 24,456,651 | [['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['N05.715.350.150', 'N06.850.490.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['F03.625.164'], ['M01.060.406.448'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Multidimensional on-line screening for ligands to the alpha3beta4 neuronal nicotinic acetylcholine receptor using an immobilized nicotinic receptor liquid chromatographic stationary phase. | The alpha3beta4 subtype of the neuronal nicotinic acetylcholine receptor (nAChR) subtype was immobilized on a liquid chromatographic support and the resulting column used for the rapid and direct on-line screening for nAChR ligands. A multidimensional chromatographic system was developed consisting of the immobilized r... | ['Chromatography, Liquid', 'Ligands', 'Mass Spectrometry', 'Receptors, Nicotinic'] | 12,016,027 | [['E05.196.181.400'], ['D27.720.470.480'], ['E05.196.566'], ['D12.776.157.530.400.400.100.500', 'D12.776.543.550.450.500.100.500', 'D12.776.543.585.400.500.100.500', 'D12.776.543.750.130.687', 'D12.776.543.750.720.360.550']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Small choroidal melanoma with massive extraocular extension: invasion through posterior scleral emissary channels. | Massive orbital extension arising from a small posterior pole uveal melanoma is rare. A 75-year-old male followed for an asymptomatic choroidal nevus developed a two and a half month history of mild decrease in visual acuity. Upon clinical examination minimal enlargement of the tumor with surrounding serous retinal det... | ['Aged', 'Choroid Neoplasms', 'Eye Enucleation', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Melanoma', 'Neoplasm Invasiveness', 'Orbit', 'Orbital Neoplasms', 'Radiography', 'Radiotherapy, Adjuvant', 'Treatment Outcome'] | 12,678,398 | [['M01.060.116.100'], ['C04.588.364.978.223', 'C11.319.494.198', 'C11.941.160.238', 'C11.941.855.198'], ['E04.540.429'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['C04.697.645', 'C23.550.727.645'], ['A02.835.232.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Systemic Inflammatory Response Syndrome and Outcomes in Intracerebral Hemorrhage. | BACKGROUND: To identify the patients at greatest odds for systemic inflammatory response syndrome (SIRS) and examine the association between SIRS and outcomes in patients presenting with intracerebral hemorrhage (ICH).METHODS: We retrospectively reviewed consecutive patients presenting to a tertiary care center from 20... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cerebral Hemorrhage', 'Female', 'Humans', 'Male', 'Middle Aged', 'Outcome Assessment, Health Care', 'Retrospective Studies', 'Systemic Inflammatory Response Syndrome', 'Young Adult'] | 26,920,909 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['E05.318.372.500.500.500', 'E05.318.372.500... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Bt crops: predicting effects of escaped transgenes on the fitness of wild plants and their herbivores. | One prominent concern about genetically modified crops is the possibility of environmental impacts from the movement of fitness-enhancing traits to wild plant populations. Decisions to deregulate Bt crops in the USA have relied strongly on arguments that these crops will not interbreed with wild relatives in the permit... | ['Animals', 'Bacillus thuringiensis', 'Bacterial Toxins', 'Biological Evolution', 'Databases, Factual', 'Ecology', 'Forecasting', 'Insect Control', 'Lepidoptera', 'Models, Theoretical', 'Plants, Edible', 'Plants, Genetically Modified', 'Risk Assessment', 'Safety'] | 15,612,280 | [['B01.050'], ['B03.300.390.400.158.218.800', 'B03.353.500.100.218.800', 'B03.510.100.100.218.800', 'B03.510.415.400.158.218.800', 'B03.510.460.410.158.218.800'], ['D23.946.123'], ['G05.045', 'G16.075'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['H01.158.273.248', 'H01.277.249'], ['I01.320'], ['N06.850.780.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Factors shaping the confocal image of the calcium spark in cardiac muscle cells. | The interpretation of confocal line-scan images of local [Ca2+]i transients (such as Ca2+ sparks in cardiac muscle) is complicated by uncertainties in the position of the origin of the Ca2+ spark (relative to the scan line) and by the dynamics of Ca(2+)-dye interactions. An investigation of the effects of these complic... | ['Animals', 'Calcium', 'Computer Simulation', 'Heart Ventricles', 'Kinetics', 'Mammals', 'Microscopy, Confocal', 'Models, Cardiovascular', 'Models, Theoretical', 'Myocardium', 'Sarcoplasmic Reticulum', 'Time Factors'] | 8,968,567 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['L01.224.160'], ['A07.541.560'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649'], ['E01.370.350.515.395', 'E05.595.395'], ['E05.599.395.161'], ['E05.599'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['A10.690.552.500.500.850', 'A11.28... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Wild-type p53 gene transfer inhibits neointima formation in human saphenous vein by modulation of smooth muscle cell migration and induction of apoptosis. | Patency of autologous human saphenous vein coronary artery bypass grafts (CABG) is compromised by intimal thickening and superimposed atherosclerosis, caused by migration of vascular smooth muscle cells (SMC) to the intima where they proliferate. Here, using adenoviral transfer, we have targeted SMCs using wild-type p5... | ['Adenoviridae', 'Apoptosis', 'Cell Division', 'Cell Movement', 'Coronary Artery Bypass', 'Gene Expression Regulation', 'Gene Transfer Techniques', 'Genes, p53', 'Genetic Therapy', 'Genetic Vectors', 'Humans', 'Muscle, Smooth, Vascular', 'Organ Culture Techniques', 'Saphenous Vein', 'Tumor Suppressor Protein p53', 'Tun... | 11,406,761 | [['B04.280.030'], ['G04.146.954.035'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.198', 'G07.568.500.180'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['G05.308'], ['E05.393.350'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415.400.385'], ['... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reduced E-Cadherin and Aberrant â-Catenin Expression are Associated With Advanced Disease in Signet-Ring Cell Carcinomas. | Signet-ring cell carcinomas (SRCCs) tend to present at higher stages and thus are generally associated with a worse prognosis. It has been postulated that a deficiency of E-cadherin may be causal in the pathogenesis of SRCC in animal models. In this study, we systemically analyzed the expression of E-cadherin and â-cat... | ['Cadherins', 'Carcinoma, Signet Ring Cell', 'Female', 'Humans', 'Male', 'Middle Aged', 'beta Catenin'] | 26,808,130 | [['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['C04.557.470.200.025.415', 'C04.557.470.590.415'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D12.776.091.249', 'D12.776.220.145.500', 'D12.776.930.130']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Isoflurane alone versus small dose propofol with isoflurane for removal of laryngeal mask airway in children-a randomized controlled trial. | OBJECTIVE: To compare the safety of laryngeal mask airway removal using two different deep anaesthesia techniques in paediatric patients.METHODS: The Randomized Control Trial was conducted at Aga Khan University Hospital, Karachi, from April 2012 to November 2013, and comprised patients aged 2-10 years scheduled for in... | ['Airway Extubation', 'Anesthesia, General', 'Anesthetics, General', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Isoflurane', 'Laryngeal Masks', 'Male', 'Pakistan', 'Propofol'] | 31,740,862 | [['E02.041.249', 'E05.008'], ['E03.155.197'], ['D27.505.696.277.100.035', 'D27.505.954.427.210.100.035'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.355.601.570'], ['E02.041.500.475', 'E02.585.578.475', 'E05.497.578.475', 'E07.700.500.450', 'J01.637.708.560.782.450'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 |
CD49d and CD26 are independent prognostic markers for disease progression in patients with chronic lymphocytic leukemia. | CLL is characterized by extremely variable clinical course. Several prognostic factors can predict disease progression and therapeutic outcomes in those patients. The aim was to evaluate the use of CD49d and CD26 as independent prognostic markers in CLL patients. The present study measured surface expression of CD49d a... | ['ADP-ribosyl Cyclase 1', 'Aged', 'Biomarkers, Tumor', 'Dipeptidyl Peptidase 4', 'Disease Progression', 'Female', 'Humans', 'Immunophenotyping', 'Integrin alpha4', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Patient Outcome Assessment', 'Prognosis', 'ZAP-70 Protein-Tyrosine Kin... | 26,142,332 | [['D08.811.277.450.430.400.060.500', 'D12.776.543.550.045'], ['M01.060.116.100'], ['D23.101.140'], ['D08.811.277.656.350.350.126', 'D08.811.277.656.959.250', 'D23.050.301.264.894.160', 'D23.101.100.894.160'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.447', 'E05.200.812.447'... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pyrone glycosides from Acosmium panamense (Benth.) Yacovlev. | Besides caffeic acid three pyrones have been isolated from aquous bark extracts from Acosmium panamense and their structures were determined using spectroscopical methods. Besides the already described desmethylyangonine its O4'-mono as well as the di(1-6)glucoside are found the first time. | ['Fabaceae', 'Gas Chromatography-Mass Spectrometry', 'Glycosides', 'Magnetic Resonance Spectroscopy', 'Molecular Conformation', 'Molecular Structure', 'Plant Stems', 'Pyrones'] | 14,577,622 | [['B01.650.940.800.575.912.250.401'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D09.408'], ['E05.196.867.519'], ['G02.111.570.820'], ['G02.111.570', 'G02.466'], ['A18.024.937'], ['D03.383.663.718']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A new sedation technique with propofol during spinal anesthesia]. | We compared our new sedation technique with propofol during spinal anesthesia (Group B, n = 50) with a previously described method by Mackenzie et al. (Group A, n = 20). In Group A, propofol was started at a rate of 6 mg.kg-1.h-1 for 10 minutes, followed by continuous infusion at a rate of 4 mg.kg-1.h-1 till the end of... | ['Adolescent', 'Adult', 'Anesthesia, Spinal', 'Conscious Sedation', 'Female', 'Humans', 'Hypnotics and Sedatives', 'Male', 'Middle Aged', 'Propofol', 'Time Factors'] | 10,933,024 | [['M01.060.057'], ['M01.060.116'], ['E03.155.086.331'], ['E03.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.277.350', 'D27.505.954.427.210.350'], ['M01.060.116.630'], ['D02.455.426.559.389.657.773'], ['G01.910.857']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Preoperative management for tricuspid regurgitation in hypoplastic left heart syndrome. | BACKGROUND: Tricuspid regurgitation (TR) is an important finding in hypoplastic left heart syndrome (HLHS). The aim of the present study was to investigate changes in the degree of TR after the preoperative management of HLHS with mechanical ventilation, and whether the improvement of TR under preoperative management w... | ['Cardiac Surgical Procedures', 'Female', 'Humans', 'Hypoplastic Left Heart Syndrome', 'Infant', 'Infant, Newborn', 'Male', 'Prognosis', 'Respiration, Artificial', 'Retrospective Studies', 'Tricuspid Valve Insufficiency', 'Ultrasonography'] | 19,419,498 | [['E04.100.376', 'E04.928.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.240.400.625', 'C14.280.400.625', 'C16.131.240.400.625'], ['M01.060.703'], ['M01.060.703.520'], ['E01.789'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bone marrow adipocytes promote tumor growth in bone via FABP4-dependent mechanisms. | Incidence of skeletal metastases and death from prostate cancer greatly increases with age and obesity, conditions which increase marrow adiposity. Bone marrow adipocytes are metabolically active components of bone metastatic niche that modulate the function of neighboring cells; yet the mechanisms of their involvement... | ['Adipocytes', 'Animals', 'Bone Marrow', 'Bone Neoplasms', 'Cell Growth Processes', 'Cell Line, Tumor', 'Fatty Acid-Binding Proteins', 'Humans', 'Interleukin-1beta', 'Male', 'Mice', 'PPAR gamma', 'Prostatic Neoplasms', 'Transfection', 'Tumor Cells, Cultured', 'Up-Regulation'] | 24,240,026 | [['A11.329.114'], ['B01.050'], ['A15.382.216'], ['C04.588.149', 'C05.116.231'], ['G04.161', 'G07.345.249.410'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.776.157.170'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010.600', 'D12.644.276.374.500.400.600', 'D12.776.467.374.465.010.600', 'D12... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cell stimulation with optically manipulated microsources. | Molecular gradients are important for various biological processes including the polarization of tissues and cells during embryogenesis and chemotaxis. Investigations of these phenomena require control over the chemical microenvironment of cells. We present a technique to set up molecular concentration patterns that ar... | ['Cell Movement', 'Cell Polarity', 'Humans', 'N-Formylmethionine Leucyl-Phenylalanine', 'Neutrophils', 'Optics and Photonics'] | 19,915,561 | [['G04.198', 'G07.568.500.180'], ['G04.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.030.676.450.440', 'D12.125.072.050.685.445', 'D12.125.142.666.500', 'D12.125.166.676.450.440', 'D12.644.456.400', 'D23.125.685'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', ... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
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