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Time course of left atrial reverse remodelling after mitral valve surgery and the impact of left ventricular global longitudinal strain in patients with chronic severe mitral regurgitation. | OBJECTIVES: We aimed to investigate the time course of left atrial (LA) reverse remodelling (LARR) after mitral valve (MV) surgery in patients with chronic severe mitral regurgitation (MR) and examine the impact of left ventricular (LV) mechanical function on LARR.METHODS: A total of 140 patients (73 males, age 54 ± 16... | ['Aged', 'Atrial Remodeling', 'Cardiac Surgical Procedures', 'Chronic Disease', 'Echocardiography, Doppler', 'Female', 'Heart Ventricles', 'Humans', 'Male', 'Middle Aged', 'Mitral Valve Insufficiency', 'Multivariate Analysis', 'Time Factors'] | 27,600,909 | [['M01.060.116.100'], ['C23.300.052', 'C23.550.113', 'G09.330.040.800'], ['E04.100.376', 'E04.928.220'], ['C23.550.291.500'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Endovascular therapy for visceral artery aneurysms. | BACKGROUND: The aim of this study was to report outcome and complications of endovascular therapy for visceral artery aneurysms (VAA).METHODS: Forty endovascular procedures for VAAs were performed in 33 patients between 2009 and 2014.RESULTS: The main indications was size (N.=15), bleeding (N.=14) and mycotic aneurysm ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aneurysm, False', 'Aneurysm, Infected', 'Blood Vessel Prosthesis Implantation', 'Computed Tomography Angiography', 'Drainage', 'Embolization, Therapeutic', 'Endovascular Procedures', 'Female', 'Humans', 'Male', 'Middle Aged', 'Registries', 'Retrospective Studies', 'Risk Factors',... | 26,418,142 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.055.090'], ['C01.069', 'C14.907.055.131'], ['E04.100.814.868.500', 'E04.650.200'], ['E01.370.350.350.810.335', 'E01.370.350.567.250', 'E01.370.350.600.350.700.810.335', 'E01.370.350.700.700.810.335', 'E01.370.350.700.810.810.568', 'E01.370.350.82... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
New Optical Imaging Reporter-labeled Anaplastic Thyroid Cancer-Derived Extracellular Vesicles as a Platform for In Vivo Tumor Targeting in a Mouse Model. | Extracellular vesicles (EVs), originating from multivesicular bodies by invagination of the endosomal membrane, are communication channels between distant cells. They are natural carriers of exogeneous cellular materials and have been exploited as drug delivery carriers in various diseases. Here, we found that tumor ce... | ['Animals', 'Antineoplastic Agents', 'Cell Line, Tumor', 'Disease Models, Animal', 'Drug Carriers', 'Extracellular Vesicles', 'Female', 'Genes, Reporter', 'Humans', 'Imidazoles', 'Luciferases, Renilla', 'Luminescent Agents', 'Mice', 'Mice, Nude', 'Optical Imaging', 'Pyrazines', 'Thyroid Carcinoma, Anaplastic', 'Thyroid... | 30,201,988 | [['B01.050'], ['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D26.255.260', 'E02.319.300.380'], ['A11.284.295.588'], ['G05.360.340.024.340.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.129.308'], ['D08.811.682.517.875', 'D12.776.532.510.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Pathogenic A2V Mutant Exhibits Distinct Aggregation Kinetics, Metal Site Structure, and Metal Exchange of the Cu2+ | A prominent current hypothesis is that impaired metal ion homeostasis may contribute to Alzheimer's disease (AD). We elucidate the interaction of Cu2+ with wild-type (WT) Aâ1-40 and the genetic variants A2T and A2V which display increasing pathogenicity as A2T<WT<A2V. Cu2+ significantly extends the lag phase in aggrega... | ['Alzheimer Disease', 'Amyloid beta-Peptides', 'Circular Dichroism', 'Copper', 'Electron Spin Resonance Spectroscopy', 'Humans', 'Kinetics', 'Microscopy, Atomic Force', 'Mutagenesis, Site-Directed', 'Peptide Fragments'] | 28,815,875 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['E05.196.867.151'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['E05.196.867.519.274'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['E... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of human immunodeficiency virus biomarkers: inferences from interval and clinical cohort studies. | INTRODUCTION: Among individuals infected with the human immunodeficiency virus (HIV), biomarkers that predict mortality are also used to determine the time when antiretroviral therapy is initiated. No studies have evaluated the impact of the frequency of marker measurements for either their predictive value of mortalit... | ['AIDS Serodiagnosis', 'Adult', 'Biomarkers', 'CD4 Lymphocyte Count', 'Cohort Studies', 'Female', 'HIV-1', 'Hemoglobins', 'Humans', 'Male', 'Middle Aged', 'Proportional Hazards Models', 'Prospective Studies', 'RNA, Viral', 'Surveys and Questionnaires'] | 19,478,669 | [['E01.370.225.812.735.060', 'E01.370.225.875.408.500', 'E05.200.812.735.060', 'E05.200.875.408.500', 'E05.478.594.760.060'], ['M01.060.116'], ['D23.101'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pediatric peritoneal dialysis in Korea: practical solutions to the problems of peritoneal dialysis for children. | PURPOSE: To find and solve the common problems of peritoneal dialysis (PD) by analyzing the clinical data of pediatric PD performed in Korea.METHODS: We looked at 264 cases of continuous ambulatory peritoneal dialysis (CAPD) and acute PD that were performed in 18 institutions of pediatric nephrology in Korea from Novem... | ['Adolescent', 'Child', 'Child, Preschool', 'Female', 'Growth', 'Humans', 'Kidney Failure, Chronic', 'Korea', 'Male', 'Peritoneal Dialysis', 'Peritoneal Dialysis, Continuous Ambulatory', 'Peritonitis', 'Retrospective Studies', 'Time Factors'] | 10,406,570 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['G07.345.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['Z01.252.474.557', 'Z01.586.407'], ['E02.870.300.650', 'E02.912.800.650'], ['E02.760.106.500', 'E02.870.300.650.500', 'E02.912.800.650.50... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Psychiatric disorder in Canberra. A standardised study of prevalence. | A standardised survey of prevalence has been carried out in a general population. The epidemiological method employed is innovative in its use of two established instruments, the GHQ and the PSE, harnessed together in a two-phase design. 756 persons were interviewed, giving a response rate of 85% in phase 1. 157 were t... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Australia', 'Cross-Sectional Studies', 'Family Characteristics', 'Female', 'Humans', 'Interviews as Topic', 'Male', 'Mental Disorders', 'Methods', 'Middle Aged', 'Sampling Studies', 'Sex Factors', 'Surveys and Questionnaires'] | 316,261 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Homogeneous electrogenerated chemiluminescence immunoassay for the detection of biomarkers by magnetic preconcentration on a magnetic electrode. | A homogeneous electrogenerated chemiluminescence (ECL) immunoassay for highly sensitive quantification of specific biomarkers based on immunomagnetic beads and homogeneous detection on a magnetic electrode was developed, for the first time. The magnetic electrode is made of a glassy carbon electrode and a series of rin... | ['Biomarkers', 'Biosensing Techniques', 'Electrodes', 'Immunoassay', 'Limit of Detection', 'Luminescence', 'Magnetics'] | 31,062,061 | [['D23.101'], ['E05.601.043'], ['E07.305.250'], ['E05.478.566', 'E05.601.470'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G01.750.250.650.665', 'G01.750.770.578.665'], ['H01.671.493']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Low Serum Levels of Prealbumin, Retinol Binding Protein, and Retinol Are Frequent in Adult Type 1 Diabetic Patients. | Aim. To determine the serum prealbumin (PA), retinol binding protein (RBP), and retinol levels in adult patients with type 1 diabetes (T1D) and to analyze some factors related to those levels. Methods. A total of 93 patients (47 women) were studied. Age, gender, BMI, duration of diabetes, chronic complications, HbA1c, ... | ['Adult', 'Age Factors', 'Body Mass Index', 'Creatinine', 'Diabetes Complications', 'Diabetes Mellitus, Type 1', 'Female', 'Humans', 'Kidney Function Tests', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Prealbumin', 'Retinol-Binding Proteins, Cellular', 'Triglycerides', 'Vitamin A'] | 28,018,921 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D03.383.129.308.207'], ['C19.246.099'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.390.400'], [... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Optimal separable algorithms to compute the reverse euclidean distance transformation and discrete medial axis in arbitrary dimension. | In binary images, the Distance Transformation (DT) and the geometrical skeleton extraction are classic tools for shape analysis. In this paper, we present time optimal algorithms to solve the reverse Euclidean distance transformation and the reversible medial axis extraction problems for d-dimensional images. We also p... | ['Algorithms', 'Artificial Intelligence', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Information Storage and Retrieval', 'Numerical Analysis, Computer-Assisted', 'Pattern Recognition, Automated', 'Signal Processing, Computer-Assisted'] | 17,224,614 | [['G17.035', 'L01.224.050'], ['G17.035.250', 'L01.224.050.375'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.400', 'L01.224.308.410'], ['L01.313.500.750.280', 'L01.470'], ['L01.224.680.700'], ['L01.399.750'], ['L01.224.800']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Paenibacillus polymyxa antagonizes oomycete plant pathogens Phytophthora palmivora and Pythium aphanidermatum. | AIM: To find sustainable alternatives to the application of synthetic chemicals for oomycete pathogen suppression.METHODS AND RESULTS: Here, we present experiments on an Arabidopsis thaliana model system in which we studied the antagonistic properties of rhizobacterium Paenibacillus polymyxa strains towards the oomycet... | ['Arabidopsis', 'Biofilms', 'Paenibacillus', 'Pest Control, Biological', 'Phytophthora', 'Plant Diseases', 'Plant Roots', 'Pythium', 'Seedlings', 'Soil Microbiology', 'Spores, Fungal'] | 19,226,403 | [['B01.650.940.800.575.912.250.157.100'], ['A20.593', 'G06.120'], ['B03.300.390.400.645', 'B03.353.500.645', 'B03.510.100.645', 'B03.510.415.400.645', 'B03.510.460.410.645'], ['N06.850.780.200.650.650'], ['B01.750.580.715'], ['G15.610'], ['A18.400'], ['B01.750.580.750'], ['A18.550', 'B01.650.819'], ['H01.158.273.540.27... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Explanatory models of somatoform disorder patients attending a psychiatry outpatient clinic: a study from North India. | BACKGROUND: The symptoms of somatoform disorders are very distressing to the sufferer as well as pose significant burden on the health-care delivery system. Although the nature of symptoms is physical, the underlying mechanisms are not clearly understood.OBJECTIVE: The purpose of this study was to assess the explanator... | ['Adult', 'Attitude to Health', 'Educational Status', 'Female', 'Humans', 'India', 'Interviews as Topic', 'Male', 'Models, Psychological', 'Religion and Psychology', 'Sex Factors', 'Somatoform Disorders'] | 24,029,246 | [['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['N01.824.196'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['E05.599.695'], ['F02.880', 'K01.844.664'], ['N05.715.350.675', 'N06.850.490.875'], ['F03.875']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
[Methodology for a rational approach to endodontic cavity access and canal preparation. Endodontic cavity access and pretreatment]. | The purpose of this study was to develop a protocol which allows for improved access cavity preparation in all clinical circumstances. From radiographic and clinical evaluation a systematic organization of 10 burs was found to be optimal for all cases encountered. This standard arrangement makes burs available for use ... | ['Dental Cavity Preparation', 'Dental Pulp Cavity', 'Humans', 'Root Canal Therapy'] | 2,633,269 | [['E06.931.325'], ['A14.549.167.900.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E06.397.778']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Support for an expanded tripartite influence model with gay men. | This study investigated whether an expanded tripartite influence model would represent gay men's experiences. This model was extended by adding partners and gay community involvement as sources of social influence and considering dual body image pathways (muscularity and body fat dissatisfaction) to muscularity enhance... | ['Adipose Tissue', 'Adolescent', 'Adult', 'Body Image', 'Culture', 'Family', 'Homosexuality, Male', 'Humans', 'Internal-External Control', 'Male', 'Middle Aged', 'Models, Psychological', 'Sexual Partners', 'Social Conformity', 'Social Environment', 'Social Facilitation', 'Somatotypes', 'Students', 'Young Adult'] | 22,036,192 | [['A10.165.114'], ['M01.060.057'], ['M01.060.116'], ['F01.752.747.792.110', 'F02.463.593.112'], ['I01.076.201.450', 'I01.880.853.100'], ['F01.829.263', 'I01.880.853.150'], ['F01.145.802.975.500.600', 'G08.686.867.500.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['M01.060.116.630'], ['E05.599... | ['Anatomy [A]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Incidence of gastrointestinal illness following wet weather recreational exposures: Harmonization of quantitative microbial risk assessment with an epidemiologic investigation of surfers. | We modeled the risk of gastrointestinal (GI) illness associated with recreational exposures to marine water following storm events in San Diego County, California. We estimated GI illness risks via quantitative microbial risk assessment (QMRA) techniques by consolidating site specific pathogen monitoring data of stormw... | ['California', 'Environmental Monitoring', 'Humans', 'Incidence', 'Recreation', 'Risk Assessment', 'Water Microbiology', 'Water Movements', 'Weather'] | 28,558,279 | [['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['N06.850.460.350.080', 'N06.850.780.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['I03.450.642'], ['E05.318.740.600.800.715', 'N04.452.87... | ['Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
No effects of pulsed radio frequency electromagnetic fields on melatonin, cortisol, and selected markers of the immune system in man. | There is growing public concern that radio frequency electromagnetic fields may have adverse biological effects. In the present study eight healthy male students were tested to see whether or not radio frequency electromagnetic fields as used in modern digital wireless telecommunication (GSM standard) have noticeable e... | ['Adult', 'Biomarkers', 'Circadian Rhythm', 'Electromagnetic Fields', 'Humans', 'Hydrocortisone', 'Immunoglobulin A', 'Male', 'Melatonin', 'Neopterin', 'Radio Waves', 'Reference Values', 'Saliva', 'Time Factors'] | 11,298,390 | [['M01.060.116'], ['D23.101'], ['G07.180.562.190'], ['G01.358.500.260', 'G01.358.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.790.651.114.619.026', 'D12.776.377.715.548.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
CXCR3 and heparin binding sites of the chemokine IP-10 (CXCL10). | The chemokine IP-10 (interferon-inducible protein of 10 kDa, CXCL10) binds the G protein-coupled receptor CXCR3, which is found mainly on activated T cells and NK cells, and plays an important role in Th1-type inflammatory diseases. IP-10 also binds to glycosaminoglycans (GAGs), an interaction thought to be important f... | ['Amino Acid Sequence', 'Animals', 'Binding Sites', 'Chemokine CXCL10', 'Chemokines, CXC', 'Chemotaxis', 'Heparin', 'Humans', 'Mice', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Mutation', 'Protein Binding', 'Protein Conformation', 'Receptors, CXCR3', 'Receptors, Chemokine'] | 12,571,234 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['D12.644.276.374.200.120.500', 'D12.776.467.374.200.120.500', 'D23.125.300.120.500', 'D23.469.200.120.500', 'D23.529.374.200.120.500'], ['D12.644.276.374.200.120', 'D12.776.467.374.200.120', 'D23.125.300.120', 'D23.469.200.120', 'D23.529.37... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
An educational tool for understanding the cardiopulmonary changes associated with aging. | Normal aging is associated with cardiac, vascular, and pulmonary adaptations that significantly affect the individual's ability to maintain homeostasis. To understand the changes associated with aging, we developed a laboratory exercise that compares and contrasts the cardiopulmonary responses to exercise in a young an... | ['Adult', 'Aged', 'Aging', 'Cardiovascular Physiological Phenomena', 'Education, Medical', 'Evaluation Studies as Topic', 'Humans', 'Physiology', 'Teaching Materials'] | 7,998,611 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['G09.330'], ['I02.358.399'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.158.782'], ['L01.178.820']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Serotype and genotype analysis of dengue virus by sequencing followed by phylogenetic analysis using samples from three mini outbreaks-2007-2009 in Pakistan. | BACKGROUND: Since the first reported outbreak of dengue hemorrhagic fever in Pakistan, several mini outbreaks have erupted in the region. Dengue virus serotype 3 (DEN-3) was first documented in 2005 outbreak in Karachi. Reports show that serotype 3 is prevalent in Lahore since 2008. Serotype 2 (DEN-2) is the major circ... | ['Bacterial Typing Techniques', 'Dengue Virus', 'Disease Outbreaks', 'Genotype', 'Humans', 'Molecular Sequence Data', 'Pakistan', 'Phylogeny', 'Polymerase Chain Reaction', 'Serotyping', 'Severe Dengue', 'Viral Proteins'] | 21,906,394 | [['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['B04.820.578.344.350.270'], ['N06.850.290'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['Z01.252.245.723'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.620.500'], ['E01.370.225.812.742', 'E01.370.225.875.150.125.890'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Cytokines in pericardial effusion of patients with inflammatory pericardial disease. | BACKGROUND: The role of inflammatory and angiogenic cytokines in patients with inflammatory pericardial effusion still remains uncertain.METHODS: We assessed pericardial and serum levels of VEGF, bFGF, IL-1â and TNF-á by ELISA in patients with inflammatory pericardial effusion (PE) of autoreactive (n = 22) and viral (n... | ['Aged', 'Coronary Artery Bypass', 'Cytokines', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Fibroblast Growth Factor 2', 'Humans', 'Immunoassay', 'Inflammation', 'Interleukin-1beta', 'Male', 'Middle Aged', 'Pericardial Effusion', 'Pericardium', 'Tumor Necrosis Factor-alpha', 'Vascular Endothelial Growth Factor A'] | 22,577,248 | [['M01.060.116.100'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Lacrimal involvement of non-Hodgkin's lymphomas and lymphomas of combined mucosal-lymphoid tissue]. | Three cases of extranodal non-Hodgkin's lymphoma affecting the lacrymal glands are reported. Analysis suggests that these belong to the group of lymphomas affecting the mucosa (MALT). | ['Aged', 'B-Lymphocytes', 'Cheek', 'Facial Neoplasms', 'Female', 'Humans', 'Immunoglobulin M', 'Lacrimal Apparatus Diseases', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Lymphoma, B-Cell', 'Male', 'Middle Aged', 'Neoplasms, Multiple Primary'] | 2,130,454 | [['M01.060.116.100'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A01.456.505.173', 'A14.194'], ['C04.588.443.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.574', 'D12.776.124.790.651.114.619.574', 'D12... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Utilization and growth patterns of sacroiliac joint injections from 2000 to 2011 in the medicare population. | BACKGROUND: The high prevalence of persistent low back pain and growing number of diagnostic and therapeutic modalities employed to manage chronic low back pain and the subsequent impact on society and the economy continue to hold sway over health care policy. Among the multiple causes responsible for chronic low bac... | ['Age Distribution', 'Humans', 'Low Back Pain', 'Medicare', 'Pain Management', 'Population Groups', 'Sacroiliac Joint', 'United States', 'Zygapophyseal Joint'] | 23,877,461 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.107.400'], ['N03.219.521.346.506.564.663', 'N03.219.521.576.343.840', 'N03.706.615.696'], ['E02.745', 'N04.590.607.500'], ['M01.686', 'N01.224.708'], ['A02.835.583.707'], ['Z01.107.567.875'], ['A02... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Anticonvulsant activity of azirino[1,2-d][1,4]benzodiazepines and related 1,4-benzodiazepines in mice. | The anticonvulsant properties of several 1,4-benzodiazepine and azirino[1,2-d][1,4]benzodiazepine (ABDZ) derivatives were studied after intraperitoneal (IP) administration in DBA/2 mice (a strain genetically susceptible to sound-induced seizures) and in Swiss mice. The anticonvulsant effects were evaluated on seizures ... | ['Animals', 'Anticonvulsants', 'Benzodiazepines', 'Carbolines', 'Cell Line', 'Convulsants', 'Flumazenil', 'GABA Modulators', 'Male', 'Membranes', 'Mice', 'Mice, Inbred DBA', 'Movement', 'Pentylenetetrazole', 'Radioligand Assay', 'Receptors, GABA-A', 'Seizures'] | 9,264,104 | [['B01.050'], ['D27.505.954.427.080'], ['D03.633.100.079.080'], ['D03.383.725.150', 'D03.633.100.473.155', 'D03.633.300.154'], ['A11.251.210'], ['D27.505.696.282.224', 'D27.505.954.427.220.224'], ['D03.633.100.079.080.070.305'], ['D27.505.519.625.240.500', 'D27.505.696.577.240.500'], ['A10.615'], ['B01.050.150.900.649.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Successful Treatment of a Late Diagnosed Esophageal Perforation with Mediastinitis and Pericardial Abscess. | We herein report a case of late diagnosed thoracic esophageal perforation. A 60-year-old man was diagnosed as an esophageal perforation with mediastinitis and pericardial abscess by detailed history taking, chest computed tomography, esophagoscopy and inflammatory findings in his blood test. Surgical drainage of medias... | ['Abscess', 'Delayed Diagnosis', 'Esophageal Perforation', 'Humans', 'Male', 'Mediastinitis', 'Middle Aged', 'Pericarditis'] | 30,501,839 | [['C01.830.025', 'C23.550.470.756.100'], ['E01.110', 'E02.760.273', 'N02.421.585.273'], ['C06.405.117.468', 'C26.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.846.187.790'], ['M01.060.116.630'], ['C14.280.720']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular cloning of a cDNA encoding mouse A15, a member of the transmembrane 4 superfamily, and its preferential expression in brain neurons. | A15, a member of the transmembrane 4 superfamily (TM4SF), was isolated by differential screening of the cDNAs that are preferentially expressed on immature T cells. As a first step in the study of the biological function of the A15 molecule, we isolated cDNAs encoding the entire coding region of mouse A15. Nucleotide s... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Brain Chemistry', 'Cloning, Molecular', 'DNA, Complementary', 'Male', 'Membrane Proteins', 'Mice', 'Mice, Inbred C57BL', 'Molecular Sequence Data', 'Nerve Tissue Proteins', 'Neurons', 'RNA, Messenger'] | 10,617,319 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.150', 'G03.185'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D12.776.543'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Strain-dependent genomic factors affect allergen-induced airway hyperresponsiveness in mice. | Asthma is etiologically and clinically heterogeneous, making the genomic basis of asthma difficult to identify. We exploited the strain-dependence of a murine model of allergic airway disease to identify different genomic responses in the lung. BALB/cJ and C57BL/6J mice were sensitized with the immunodominant allergen ... | ['Airway Resistance', 'Allergens', 'Animals', 'Antigens, Dermatophagoides', 'Arthropod Proteins', 'Asthma', 'Bronchial Hyperreactivity', 'Bronchial Provocation Tests', 'Bronchoconstriction', 'Bronchoconstrictor Agents', 'Cysteine Endopeptidases', 'Cytokines', 'Disease Models, Animal', 'Gene Expression Profiling', 'Gene... | 21,378,263 | [['E01.370.386.700.050', 'G09.772.060'], ['D23.050.063'], ['B01.050'], ['D23.050.181'], ['D12.776.093'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C08.127.210'], ['E01.370.386.700.125'], ['G09.772.705.700.080'], ['D27.505.696.663.050.100', 'D27.505.954.796.170'], ['D08.811.277.656.262.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Markedly improving survival of neuroblastoma: a 30-year analysis of 1,646 patients. | We sought to define current incidence trends and outcomes for pediatric patients with neuroblastoma. The SEER registry was queried from 1973 to 2002. Overall, 1,646 patients with neuroblastoma were identified. The annual incidence has remained unchanged at 0.9 per 100,000. The median age of the population was 1 year, w... | ['Chi-Square Distribution', 'Female', 'Humans', 'Incidence', 'Infant', 'Infant, Newborn', 'Least-Squares Analysis', 'Male', 'Neuroblastoma', 'Prognosis', 'Proportional Hazards Models', 'SEER Program', 'Survival Rate', 'United States'] | 17,476,512 | [['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.703'], ['M01.060.703.520'], ['E05.318.740.750.400', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Collaborative hospital orientation: simulation as a teaching strategy. | For nurses, the stress caused by entering a new place of employment may give rise to insecurity and a lack of confidence. Lack of confidence in one's nursing skills can affect performance and, ultimately, patient care and safety. In healthcare, growing fiscal constraints have resulted in lost resources, and support for... | ['Academic Medical Centers', 'Clinical Competence', 'Communication', 'Cooperative Behavior', 'Curriculum', 'Hospitals, University', 'Humans', 'Inservice Training', 'Interdisciplinary Communication', 'Nursing Staff, Hospital', 'Ontario', 'Patient Simulation', 'Personnel Selection', 'Preceptorship', 'Quality Assurance, H... | 24,860,953 | [['N02.278.020'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['F01.145.209', 'L01.143'], ['F01.145.813.115'], ['I02.158'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.574'], ['F01.829.401.205.249', 'L01.143.865.500'], ['M01.526.485.680.490', 'M01.526.48... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Patients' profiles in end stage coronary artery disease. Indications for treatment with transmyocardial laser revascularisation. | There is a subgroup of patients with coronary artery disease who are refractory to the therapeutical methods so far applied. We report on 128 patients who fulfill this definition and have therefore undergone pure transmyocardial laser revascularisation (TMLR) or transmyocardial laser revascularisation in combination wi... | ['Aged', 'Cardiac Output, Low', 'Chronic Disease', 'Coronary Disease', 'Diagnostic Imaging', 'Female', 'Heart Failure', 'Hemodynamics', 'Humans', 'Laser Therapy', 'Male', 'Middle Aged', 'Myocardial Revascularization', 'Myocardium', 'Patient Selection', 'Prognosis', 'Recurrence', 'Treatment Failure'] | 9,285,237 | [['M01.060.116.100'], ['C14.280.148', 'C23.888.192'], ['C23.550.291.500'], ['C14.280.647.250', 'C14.907.585.250'], ['E01.370.350'], ['C14.280.434'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['M01.060.116.630'], ['E04.100.376.719', 'E04.928.220.520'], ['A02.633.580', ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Two separate outbreaks of Salmonella enteritidis phage type 14b food poisoning linked to the consumption of the same type of frozen food. | OBJECTIVES: To ascertain, using a combination of epidemiological, environmental and microbiological methods of investigation, a possible link between two outbreaks of salmonella food poisoning.METHODS: Case-control studies were carried out on the known at-risk populations. Environmental investigations took place in the... | ['Adult', 'Aged', 'Aged, 80 and over', 'Bacteriophage Typing', 'Case-Control Studies', 'Cooking', 'Disease Outbreaks', 'Eggs', 'Electrophoresis, Gel, Pulsed-Field', 'Female', 'Frozen Foods', 'Humans', 'Male', 'Middle Aged', 'Restaurants', 'Salmonella Food Poisoning', 'Salmonella enteritidis', 'Seafood', 'Surveys and Qu... | 16,879,847 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.875.150.125.150', 'E05.200.875.150.125.150'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['J01.576.423.200.200'], ['N06.850.290'], ['G07.203.300.470', 'J02.500.470'], ['E05.196.401.220', 'E05.301.300.220'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
A prospective, single-blind, randomized controlled trial of antiseptic cream for recurrent epistaxis in childhood. | Epistaxis is common in children. Trials show antiseptic cream is as effective as cautery, but it is not known whether either is better than no treatment. We wished to know the efficacy of cream in children with recurrent epistaxis. The design was a single-blind, prospective, randomized controlled trial set in the Otola... | ['Administration, Topical', 'Adolescent', 'Anti-Infective Agents, Local', 'Child', 'Child, Preschool', 'Chlorhexidine', 'Drug Combinations', 'Epistaxis', 'Female', 'Humans', 'Male', 'Neomycin', 'Ointments', 'Prospective Studies', 'Recurrence', 'Single-Blind Method'] | 11,843,924 | [['E02.319.267.120'], ['M01.060.057'], ['D27.505.954.122.187'], ['M01.060.406'], ['M01.060.406.448'], ['D02.078.370.141.100'], ['D26.310'], ['C08.460.261', 'C09.603.261', 'C23.550.414.712', 'C23.888.852.040'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.408.051.623'], ['D26.255.640'], ['E05.318.372.500.750.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Causes of death and relative survival of older women after a breast cancer diagnosis. | PURPOSE: To understand the impact of breast cancer on older women's survival, we compared survival of older women diagnosed with breast cancer with matched controls. METHODS Using the linked 1992 to 2003 Surveillance, Epidemiology, and End Results (SEER) -Medicare data set, we identified women age 67 years or older who... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Carcinoma, Intraductal, Noninfiltrating', 'Case-Control Studies', 'Cause of Death', 'Comorbidity', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Life Expectancy', 'Mammography', 'Medicare', 'Neoplasm Staging', 'Odds Ratio', 'Prognosis', 'Proportional Haz... | 21,402,602 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.275', 'C04.557.470.200.240.187.250', 'C04.557.470.615.275'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.308.985.550.250', 'N01.22... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
MRI-based breast volumetry-evaluation of three different software solutions. | As lipofilling of the female breast is becoming more popular in plastic surgery, the use of MRI to assess breast volume has been employed to control postoperative results. Therefore, we sought to evaluate the accuracy of magnetic resonance imaging (MRI)-based breast volumetry software tools by comparing the measurement... | ['Breast', 'Breast Implants', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Linear Models', 'Magnetic Resonance Imaging', 'Middle Aged', 'Silicones', 'Software Validation', 'Treatment Outcome'] | 20,066,465 | [['A01.236'], ['E07.695.140'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Effects of intensive counseling on client outcome in a methadone maintenance program. | This program evaluation examines intensification of rehabilitation services in an existing Methadone Maintenance Treatment Program (MMTP). The investigation includes a description of initial organizational problems, of the strategy and tactics used, and of formal and informal forces used to implement specific changes. ... | ['Adult', 'Counseling', 'Employment', 'Female', 'Goals', 'Heroin Dependence', 'Humans', 'Male', 'Methadone', 'Outcome and Process Assessment, Health Care', 'Social Adjustment'] | 7,275,394 | [['M01.060.116'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['N01.824.245'], ['F01.658.500'], ['C25.775.643.500.400', 'F03.900.647.500.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.522.675'], ['N04.761.559', 'N05.715.360.575'], ['F01.145.813.621']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Uterine arterial embolization for the treatment of diffuse leiomyomatosis. | Diffuse leiomyomatosis of the uterus is an extremely rare condition and presents as a diffuse involvement of the myometrium by numerous leiomyomata. Despite patients being in only the third or fourth decades of life, all previously reported patients with this condition have undergone hysterectomy because myomectomy is ... | ['Adult', 'Angiography', 'Arteries', 'Embolization, Therapeutic', 'Female', 'Humans', 'Leiomyomatosis', 'Magnetic Resonance Imaging', 'Radiography, Interventional', 'Uterine Neoplasms', 'Uterus'] | 12,761,320 | [['M01.060.116'], ['E01.370.350.700.060', 'E01.370.370.050'], ['A07.015.114'], ['E02.520.360', 'E02.926.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.590.450.465'], ['E01.370.350.825.500'], ['E01.370.350.700.725', 'E04.502.780'], ['C04.588.945.418.948', 'C13.351.500.852.762', 'C13.351.937.418.87... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The uncertainty of the pendulum method for the determination of the moment of inertia. | The purpose of this study was to quantify the uncertainty of the pendulum method for determining the moment of inertia of an object using various suspension distances. Experimental data were collected on a known geometric solid and partial differential equations were derived to calculate the uncertainty. Repeated measu... | ['Acceleration', 'Animals', 'Anthropometry', 'Biomechanical Phenomena', 'Body Size', 'Computer Simulation', 'Extremities', 'Humans', 'Joints', 'Models, Biological', 'Organ Size', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 16,442,329 | [['G01.482.107'], ['B01.050'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['G01.154.090', 'G01.374.089'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['L01.224.160'], ['A01.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583'], ['E05.599.395'], ['E... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Photoenhanced oxidative DNA cleavage with non-heme iron(II) complexes. | The DNA cleavage activity of iron(II) complexes of a series of monotopic pentadentate N,N-bis(2-pyridylmethyl)-N-bis(2-pyridyl)methylamine (N4Py)-derived ligands (1-5) was investigated under laser irradiation at 473, 400.8, and 355 nm in the absence of a reducing agent and compared to that under ambient lighting. A sig... | ['DNA Cleavage', 'DNA, Bacterial', 'Escherichia coli', 'Ferrous Compounds', 'Lasers', 'Ligands', 'Oxidation-Reduction', 'Photochemical Processes'] | 21,058,672 | [['G02.111.210', 'G05.193'], ['D13.444.308.212'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D01.490.200'], ['E07.632.490', 'E07.710.520'], ['D27.720.470.480'], ['G02.700', 'G03.295.531'], ['G02.740']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tauroursodeoxycholic acid mobilizes alpha-PKC after uptake in human HepG2 hepatoma cells. | BACKGROUND: Tauroursodeoxycholic acid (TUDCA) may exert anticholestatic effects via Ca(++)- and alpha-protein kinase C (alpha-PKC)-dependent apical vesicular insertion of canalicular transporters in cholestatic hepatocytes (Hepatology 2001; 33: 1206-16). Tauroursodeoxycholic acid is mainly taken up into liver cells by ... | ['Biological Transport', 'Carrier Proteins', 'Cell Fractionation', 'Hepatocytes', 'Humans', 'Isoenzymes', 'Membrane Transport Proteins', 'Organic Anion Transporters, Sodium-Dependent', 'Protein Kinase C', 'Protein Kinase C-alpha', 'Symporters', 'Taurochenodeoxycholic Acid', 'Tetradecanoylphorbol Acetate', 'Transfection... | 12,059,989 | [['G03.143'], ['D12.776.157'], ['E05.242.251'], ['A11.436.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.348', 'D12.776.800.300'], ['D12.776.157.530', 'D12.776.543.585'], ['D12.776.157.530.450.074.500.687', 'D12.776.543.585.450.074.500.812'], ['D08.811.913.696.620.682.700.725'], ['D08.811.913.696.620... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spanish Jesuits in the Philippines: geophysical research and synergies between science, education and trade, 1865-1898. | In 1865, Spanish Jesuits founded the Manila Observatory, the earliest of the Far East centres devoted to typhoon and earthquake studies. Also on Philippine soil and under the direction of the Jesuits, in 1884 the Madrid government inaugurated the first Meteorological Service in the Spanish Kingdom, and most probably in... | ['Colonialism', 'Commerce', 'Education', 'Geological Phenomena', 'Geology', 'History, 19th Century', 'Meteorology', 'Philippines', 'Religious Personnel', 'Spain'] | 25,470,886 | [['I01.696.116'], ['J01.219'], ['I02'], ['G01.311'], ['H01.277.562'], ['K01.400.504.937'], ['H01.277.687', 'H01.671.547'], ['Z01.252.145.671', 'Z01.639.790'], ['M01.526.799'], ['Z01.542.846']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Humanities [K]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 |
Deep infection after total hip replacement: a method for national incidence surveillance. | OBJECTIVE: The purpose of this study was to estimate the incidence of deep periprosthetic joint infections (PJIs) after primary total hip replacement (THR) in Sweden prior to the introduction of a national initiative to reduce these infections.DESIGN: Prospective open cohort study with 2 years follow-up of each subject... | ['Adult', 'Anti-Bacterial Agents', 'Arthroplasty, Replacement, Hip', 'Female', 'Follow-Up Studies', 'Hip Prosthesis', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Prospective Studies', 'Prosthesis-Related Infections', 'Reoperation', 'Risk Factors', 'Severity of Illness Index', 'Staphylococcal Infections', 'Staphyloco... | 25,419,771 | [['M01.060.116'], ['D27.505.954.122.085'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Fucoxanthin induces apoptosis in human cervical cancer cell line HeLa via PI3K/Akt pathway. | Cervical cancer (CC) is a malignant neoplasm arising from cells originating in the cervix uteri, among the top causes of death from cancer in women. In a gene expression profiling study of metabolic response to treatment, PI3K/Akt signaling pathway are associated with the development of CC. A common mechanism of Akt ac... | ['Adenosine Triphosphate', 'Animals', 'Apoptosis', 'Blotting, Western', 'Cell Proliferation', 'Female', 'Flow Cytometry', 'HeLa Cells', 'Humans', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'NF-kappa B', 'Oxygen Consumption', 'Phosphatidylinositol 3-Kinase', 'Phosphorylation', 'Proto-Oncogene Proteins c-akt', 'Signal ... | 25,113,250 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['G04.146.954.035'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.161.750', 'G07.345.249.410.750'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The stream/bounce effect occurs for luminance- and disparity-defined motion targets. | We generalised the stream/bounce effect to dynamic random element displays containing luminance- or disparity-defined targets. Previous studies investigating audio-visual interactions in this context have exclusively employed motion sequences with luminance-defined disks or squares and have focused on properties of the... | ['Acoustic Stimulation', 'Analysis of Variance', 'Auditory Perception', 'Contrast Sensitivity', 'Discrimination, Psychological', 'Humans', 'Motion Perception', 'Optical Illusions', 'Photic Stimulation', 'Vision, Ocular'] | 22,896,912 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F02.463.593.071', 'G07.888.125'], ['E01.370.380.850.950.500', 'F02.463.593.778.435.110', 'F02.463.593.932.281', 'F02.463.593.932.901.500', 'G14.940.500'], ['F02.463.593.257'], ['B01.050.150.900.649.313.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A refined, efficient mean solvation force model that includes the interior volume contribution. | A refined implicit aqueous solvation model is proposed for the simulation of biomolecules without the explicit inclusion of the solvent degrees of freedom. The mean force due to solvation is approximated by the derivative of a simple analytic function of the solvent accessible surface area combined with two atomic solv... | ['Animals', 'Computer Simulation', 'Humans', 'Models, Chemical', 'Models, Molecular', 'Proteins', 'Solvents', 'Thermodynamics', 'Water'] | 21,434,626 | [['B01.050'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.495'], ['E05.599.595'], ['D12.776'], ['D27.720.844'], ['G01.906'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Double concentric craniotomy for a craniocerebral penetrating nail. Case report and technical note. | BACKGROUND: Craniocerebral penetrating injuries from nail-gun accidents are rare and usually are discovered immediately after the trauma. Several surgical procedures have been described to extract a foreign body that is infixed in the skull and has penetrated the surrounding structures; blind extraction, craniectomy, a... | ['Accidents, Occupational', 'Adult', 'Brain Injuries', 'Craniotomy', 'Foreign Bodies', 'Humans', 'Male', 'Motor Cortex', 'Radiography', 'Seizures', 'Skull', 'Treatment Outcome'] | 16,231,428 | [['N06.850.135.240'], ['M01.060.116'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['E04.525.190'], ['C26.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['E01.370.350.700'], ['C10.597.742', 'C23.888.592.742'], ['A02.... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A Macrophage Migration Inhibitory Factor Polymorphism Is Associated with Autoimmune Hepatitis Severity in US and Japanese Patients. | BACKGROUND: The pathogenesis of autoimmune hepatitis (AIH) is incompletely understood. Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine implicated in the pathophysiology of multiple autoimmune diseases. We recently reported that MIF expression was increased in a US AIH cohort. MIF expression in ... | ['Adrenal Cortex Hormones', 'Adult', 'Alanine Transaminase', 'Antigens, Differentiation, B-Lymphocyte', 'Asian Continental Ancestry Group', 'Case-Control Studies', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Genetic Predisposition to Disease', 'Hepatitis, Autoimmune', 'Histocompatibility Antigens Class II', 'Humans... | 27,696,094 | [['D06.472.040'], ['M01.060.116'], ['D08.811.913.477.700.100'], ['D23.050.301.264.051', 'D23.101.100.150'], ['M01.686.508.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.36... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Moringa oleifera stem extract protect skin keratinocytes against oxidative stress injury by enhancement of antioxidant defense systems and activation of PPARá. | Oxidative stress is an important cause of skin injury induced by UVB radiation. Moringa oleifera also known as horseradish tree or drumstick tree, have multiple nutraceutical or pharmacological functions. However, whether Moringa oleifera protects skin against oxidative stress injury remains unknown. To investigate the... | ['Animals', 'Antioxidants', 'Catalase', 'Cell Death', 'Cell Line', 'Cytoprotection', 'Epidermis', 'Female', 'Humans', 'Hydrogen Peroxide', 'Keratinocytes', 'Mice, Inbred BALB C', 'Molecular Docking Simulation', 'Moringa oleifera', 'Oxidative Stress', 'PPAR alpha', 'Plant Extracts', 'Plant Stems', 'Protective Agents', '... | 30,077,837 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D08.811.682.732.332'], ['G04.146'], ['A11.251.210'], ['G07.690.773.500'], ['A10.272.497', 'A17.815.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Role of pharmacokinetic effects in the potentiation of morphine analgesia by L-type calcium channel blockers in mice. | The present study was designed to investigate the pharmacokinetic interaction of morphine with three classes of L-type calcium channel blockers (CCB) and its relationship to morphine-induced mechanical antinociception in mice. The CCB classes were benzothiazepine (diltiazem), dihydropyridine (nimodipine), and phenylalk... | ['Analgesia', 'Animals', 'Area Under Curve', 'Brain', 'Brain Chemistry', 'Calcium Channel Blockers', 'Calcium Channels, L-Type', 'Diltiazem', 'Dose-Response Relationship, Drug', 'Drug Synergism', 'Injections, Subcutaneous', 'Male', 'Mice', 'Mice, Inbred ICR', 'Morphine', 'Nimodipine', 'Pain', 'Pain Measurement', 'Physi... | 15,037,808 | [['E03.091'], ['B01.050'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['A08.186.211'], ['G02.111.150', 'G03.185'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['D12.776.157.530.400.150.400', 'D12.776.543.550.450.150.400', 'D12.776.543.585.400.150.400'], ['D0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Conditional probability in the diagnosis of coronary artery disease: a future tool for eliminating unnecessary testing? | Approximately 30% of the 300,000 coronary arteriograms done annually in the United States yield normal results. To see if the use of conditional probability in the diagnosis of coronary artery disease (CAD) could aid in predicting these normal results, we retrospectively assessed 96 patients with chest pain but without... | ['Angiography', 'Bayes Theorem', 'Computers', 'Coronary Angiography', 'Coronary Disease', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Software'] | 6,688,479 | [['E01.370.350.700.060', 'E01.370.370.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['L01.224.230.260'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250', 'C14.907.585.250'], ['B01.050.150.900.649.313.988.400.112... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Strategic Grassland Bird Conservation throughout the Annual Cycle: Linking Policy Alternatives, Landowner Decisions, and Biological Population Outcomes. | Grassland bird habitat has declined substantially in the United States. Remaining grasslands are increasingly fragmented, mostly privately owned, and vary greatly in terms of habitat quality and protection status. A coordinated strategic response for grassland bird conservation is difficult, largely due to the scope an... | ['Agriculture', 'Animal Migration', 'Animals', 'Birds', 'Computer Simulation', 'Conservation of Natural Resources', 'Decision Making', 'Grassland', 'Population Dynamics', 'Public Policy', 'Seasons', 'United States'] | 26,569,108 | [['J01.040'], ['F01.145.113.069.500'], ['B01.050'], ['B01.050.150.900.248'], ['L01.224.160'], ['J01.256', 'N06.230.080'], ['F02.463.785.373'], ['G16.500.275.157.531', 'N06.230.124.390'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['I01.655.500.608', 'I01.880.604.825.608', 'N03.623.500.608'], ['G01.910.645.6... | ['Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 |
Survival of patients with type 1 diabetes receiving renal replacement therapy in 1980-2007. | OBJECTIVE: Risks of end-stage renal disease and premature death in patients with type 1 diabetes have declined over the past decades. Data on the survival of patients receiving renal replacement therapy (RRT) are, however, limited. We investigated whether survival of patients with type 1 diabetes receiving RRT has impr... | ['Adult', 'Diabetes Mellitus, Type 1', 'Female', 'Humans', 'Male', 'Middle Aged', 'Renal Replacement Therapy'] | 20,435,795 | [['M01.060.116'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.870']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A vesicular stomatitis virus (cytomegalovirus) pseudotype and its use in neutralization tests. | Infection with vesicular stomatitis virus (VSV) of human diploid cells preinfected with the AD-169 strain of human cytomegalovirus (CMV) resulted in the formation of a VSV (CMV) pseudotype. Its formation was favored by increasing the bicarbonate content in doubly-infected cultures. The pseudotype was capable of infecti... | ['Adult', 'Antibodies, Viral', 'Child', 'Complement Fixation Tests', 'Cytomegalovirus', 'Humans', 'Mutation', 'Neutralization Tests', 'Phenotype', 'Vesicular stomatitis Indiana virus', 'Viral Proteins'] | 227,814 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Bacterial contamination of hair washing liquids]. | To determine the extent of contamination by bacteria of hair-washing shampoo and rinse used professionally at barber shops and hair-dressing saloons, quantitative isolation of bacteria were performed by using a total of 39 samples of shampoo and rinse fluid obtained from 17 facilities. It was found that a maximal numbe... | ['Bacteria', 'Cross Infection', 'Gram-Negative Bacteria', 'Hair Preparations', 'Humans'] | 8,151,142 | [['B03'], ['C01.248', 'C23.550.291.875.500'], ['B03.440'], ['D27.720.269.430'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Knowledge about affective disorders and outcome of depression. | BACKGROUND: For affective disorders, imparting information about the illness has become standard treatment. Despite the great clinical relevance of knowledge about depression, few empirical studies on this subject have been carried out. The aim of the study was to identify the prognostic value of knowledge about affect... | ['Adult', 'Aged', 'Attitude to Health', 'Awareness', 'Chronic Disease', 'Depressive Disorder, Major', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Mood Disorders', 'Patient Education as Topic', 'Recurrence', 'Surveys and Questionnaires'] | 17,383,010 | [['M01.060.116'], ['M01.060.116.100'], ['F01.100.150', 'N05.300.150'], ['F02.463.188.150'], ['C23.550.291.500'], ['F03.600.300.375'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F03.600'], ['I02.233.33... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Isolation of proteolytic rumen bacteria by use of selective medium containing leaf fraction 1 protein (ribulosebisphosphate carboxylase). | The principle proteolytic bacteria isolated from bovine rumen contents by virtue of the ability to obtain nitrogen from the proteolysis of leaf fraction 1 protein (ribulosebisphosphate carboxylase, EC 4.1.1.39) were identified as Streptococcus bovis and Butyrivibrio spp. Substitution of fresh fodder, rich in soluble pr... | ['Animals', 'Caseins', 'Cattle', 'Culture Media', 'Gram-Negative Anaerobic Bacteria', 'Plant Proteins', 'Ribulose-Bisphosphate Carboxylase', 'Rumen', 'Streptococcus'] | 6,881,961 | [['B01.050'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['B01.050.150.900.649.313.500.380.271'], ['D27.720.470.305', 'E07.206'], ['B03.440.425'], ['D12.776.765'], ['D08.811.520.224.125.800', 'D12.776.765.199.499'], ['A13.869.804'], ['B03.353.750.737.872', 'B03.510.400.800.872', 'B03.510.550.737.872']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structure and functions of endotoxin-binding peptides derived from CAP18. | CAP18 (cationic antimicrobial protein, 18kDa) is a 142 amino acid protein originally isolated from rabbit granulocytes using agglutination of LPS-coated erythrocytes as an assay. CAP-18 is composed of an N-terminal domain of unknown function (CAP181-105) and a C-terminal LPS-binding domain (CAP18106-142). Synthetic CAP... | ['Acute-Phase Proteins', 'Amino Acid Sequence', 'Animals', 'Anti-Bacterial Agents', 'Antimicrobial Cationic Peptides', 'Carrier Proteins', 'Cathelicidins', 'DNA, Complementary', 'Endotoxins', 'Humans', 'In Vitro Techniques', 'Lipopolysaccharides', 'Male', 'Membrane Glycoproteins', 'Mice', 'Mice, Inbred C57BL', 'Molecul... | 8,524,937 | [['D12.776.124.050'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D27.505.954.122.085'], ['D12.644.050', 'D12.776.543.695.054'], ['D12.776.157'], ['D12.644.050.099', 'D12.776.543.695.054.099'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D23.946.123.329'], ['B01.050.1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The Saccharomyces cerevisiae DNA polymerase alpha catalytic subunit interacts with Cdc68/Spt16 and with Pob3, a protein similar to an HMG1-like protein. | We have used DNA polymerase alpha affinity chromatography to identify factors involved in eukaryotic DNA replication in the yeast Saccharomyces cerevisiae. Two proteins that bound to the catalytic subunit of DNA polymerase alpha (Pol1 protein) are encoded by the essential genes CDC68/SPT16 and POB3. The binding of both... | ['Alleles', 'Amino Acid Sequence', 'Base Sequence', 'Carrier Proteins', 'Cell Cycle', 'Cell Cycle Proteins', 'Cell Survival', 'DNA Polymerase I', 'DNA Polymerase II', 'DNA Replication', 'DNA, Fungal', 'DNA-Binding Proteins', 'Fungal Proteins', 'High Mobility Group Proteins', 'Molecular Sequence Data', 'Precipitin Tests... | 9,199,353 | [['G05.360.340.024.340.030'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.157'], ['G04.144'], ['D12.776.167'], ['G04.346'], ['D08.811.913.696.445.308.300.225'], ['D08.811.913.696.445.308.300.230'], ['G02.111.225', 'G05.226'], ['D13.444.308.300'], ['D1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Partial liberalization of visiting policies and ICU staff: a before-and-after study. | PURPOSE: To investigate possible psychological distress among staff after partial liberalization of visiting policies in intensive care units (ICUs).METHODS: We surveyed eight Italian ICUs planning to increase daily visiting to at least 8 h. Participants completed the Maslach-Jackson Burnout Inventory and the State-Tra... | ['Adult', 'Burnout, Professional', 'Female', 'Health Personnel', 'Humans', 'Intensive Care Units', 'Italy', 'Male', 'Middle Aged', 'Organizational Policy', 'Stress, Psychological', 'Surveys and Questionnaires', 'Visitors to Patients', 'Workforce'] | 24,013,436 | [['M01.060.116'], ['C24.580.500', 'F01.145.126.990.367.500', 'F02.830.900.333.500'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['Z01.542.489'], ['M01.060.116.630'], ['I01.655.500.550', 'I01.880.604.825.550', 'N03.623.500.550'], ['F01.145.126.990', 'F02.830.900'], ... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A novel high-content flow cytometric method for assessing the viability and damage of rat retinal ganglion cells. | PURPOSE: The aim of the study was to develop a high-content flow cytometric method for assessing the viability and damage of small, medium, and large retinal ganglion cells (RGCs) in N-methyl-D-aspartic acid (NMDA)-injury model.METHODS/RESULTS: Retinal toxicity was induced in rats by intravitreal injection of NMDA and ... | ['Animals', 'Cell Survival', 'Flow Cytometry', 'N-Methylaspartate', 'Rats', 'Retinal Ganglion Cells', 'Vitreous Body'] | 22,457,807 | [['B01.050'], ['G04.346'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['D12.125.067.500.400', 'D12.125.119.170.400'], ['B01.050.150.900.649.313.992.635.505.700'], ['A08.675.650.850.875', 'A09.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Non-invasive brain stimulation improves object-location learning in the elderly. | Remembering the location of objects, an integral part of everyday life, is known to decline with advancing age and early in the course of neurodegenerative dementia. Here, we aimed to test if object-location learning and its retention could be modified by noninvasive brain stimulation. In a group of 20 elderly (mean ag... | ['Female', 'Humans', 'Learning', 'Male', 'Middle Aged', 'Pattern Recognition, Visual', 'Space Perception', 'Spatial Behavior', 'Task Performance and Analysis', 'Transcranial Magnetic Stimulation', 'Treatment Outcome'] | 21,684,040 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['M01.060.116.630'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F02.463.593.778'], ['F01.145.875'], ['F02.784.412.846', 'F02.784.692.746', 'F02.808.600'], ['E02.621.820'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Myocardial hypertrophy in patients with hypertensive disease: the role of genetic polymorphism of beta-adrenoreactive structures]. | Aim of the study was investigation of association of polymorphic markers Gly389Arg and Ser49Gly of ADRB1 gene, Gly1l6Arg and Glu27Gln of ADRB2 gene, Trp64Arg of ADRB3 gene, and 825 of GNB3 gene with structural and functional peculiarities of the left ventricular (LV) myocardium in patients with hypertensive disease. We... | ['Alleles', 'DNA', 'Female', 'Genetic Predisposition to Disease', 'Genotype', 'Heart Ventricles', 'Heterotrimeric GTP-Binding Proteins', 'Humans', 'Hypertension', 'Hypertrophy, Left Ventricular', 'Male', 'Middle Aged', 'Myocardium', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'Protein Subunits', 'Receptors, A... | 20,144,152 | [['G05.360.340.024.340.030'], ['D13.444.308'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['A07.541.560'], ['D08.811.277.040.330.300.200', 'D12.644.360.360', 'D12.776.157.325.332', 'D12.776.476.375', 'D12.776.543.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C14.280.195.400', 'C23... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Too short stature, too many stigmata. | Dyskeratosis congenita (DC) is a rare disease characterised by bone marrow failure and skin manifestations. Patients with DC may exhibit short stature that is not usually related to growth hormone (GH) deficiency. Replacement treatment with GH should be done cautiously as it can predispose to haematological malignancy.... | ['Bone Marrow Transplantation', 'Cell Cycle Proteins', 'Child', 'Dyskeratosis Congenita', 'Heterozygote', 'Human Growth Hormone', 'Humans', 'Male', 'Nuclear Proteins', 'Polymorphism, Single Nucleotide'] | 22,798,484 | [['E02.095.147.725.040', 'E04.936.580.040'], ['D12.776.167'], ['M01.060.406'], ['C15.378.190.223.500.750', 'C16.131.831.150', 'C16.320.322.108', 'C16.320.850.235', 'C17.800.804.150', 'C17.800.827.235'], ['G05.380.383'], ['D06.472.699.631.525.425.875', 'D12.644.548.691.525.425.875'], ['B01.050.150.900.649.313.988.400.11... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mutational analysis of Greek patients with suspected hereditary neuropathy with liability to pressure palsies (HNPP): a 15-year experience. | There has been limited information from population studies regarding the overall frequency of the common 1.5-Mb 17p11.2 deletion and even scarcer data regarding the overall frequency of PMP22 micromutations in patients with a clinical suspicion of hereditary neuropathy with liability to pressure palsies (HNPP). We have... | ['Adolescent', 'Adult', 'Aged', 'Arthrogryposis', 'Child', 'Chromosome Deletion', 'Chromosomes, Human, Pair 17', 'DNA Mutational Analysis', 'Female', 'Greece', 'Hereditary Sensory and Motor Neuropathy', 'Humans', 'Male', 'Middle Aged', 'Mutation', 'Myelin Proteins', 'Phenotype', 'Smith-Magenis Syndrome', 'Young Adult'] | 26,110,377 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C05.550.150', 'C05.651.102', 'C05.660.077', 'C16.131.621.077'], ['M01.060.406'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['A11.284.187.520.300.415.425... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Primary total hip arthroplasty with Duraloc cup in patients younger than 50 years: a 5- to 7-year follow-up study. | We evaluated the clinical and radiographic results of 67 (64 patients) cementless Duraloc-300 cups for young active patients after a mean follow-up period of 6.2 years. The preoperative mean Harris hip score improved from 46.24 to 96.5 points at 5 years. The survivorship of the cup, using radiographically confirmed ase... | ['Acetabulum', 'Adult', 'Arthroplasty, Replacement, Hip', 'Biocompatible Materials', 'Female', 'Follow-Up Studies', 'Hip Joint', 'Hip Prosthesis', 'Humans', 'Joint Diseases', 'Male', 'Middle Aged', 'Osteolysis', 'Polyethylenes', 'Radiography', 'Young Adult'] | 19,195,836 | [['A02.835.232.043.825.108'], ['M01.060.116'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A02.835.583.411'], ['E07.695.400.400'], ['B01.050.150.900.649.... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
KCl cotransport in HbAA and HbSS red cells: activation by intracellular acidity and disappearance during maturation. | Low intracellular pH was shown to be a potent activator of the KCl cotransport system in HbSS red cells, and in reticulocyte-rich fractions of HbAA red cells. Rheological experiments indicated that cell dehydration via the KCl cotransporter in response to low pH decreased the filterability of HbSS red cells. In vitro m... | ['Anemia, Sickle Cell', 'Biological Transport', 'Bumetanide', 'Carrier Proteins', 'Choline', 'Dehydration', 'Erythrocyte Aging', 'Erythrocyte Deformability', 'Erythrocyte Volume', 'Hemochromatosis', 'Humans', 'Hydrogen-Ion Concentration', 'Intracellular Fluid', 'Osmolar Concentration', 'Ouabain', 'Potassium Chloride', ... | 1,805,601 | [['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['G03.143'], ['D02.065.884.150', 'D02.241.223.100.050.300.200', 'D02.455.426.559.389.127.020.452.500', 'D02.886.590.700.150'], ['D12.776.157'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'],... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antioxidant enzymes levels in children with juvenile rheumatoid arthritis. | UNLABELLED: Pathogenic mechanism of chronic inflammation is associated with increased production of superoxide anion and hydrogen peroxide. In the neutralization process of that anions, superoxid dismutase (SOD), catalase (CAT), and glutation peroxidase (GPx) are key enzymes. Aim of study consists of establishing of so... | ['Adolescent', 'Arthritis, Juvenile', 'Biomarkers', 'Catalase', 'Child', 'Child, Preschool', 'Glutathione Peroxidase', 'Humans', 'Sensitivity and Specificity', 'Superoxide Dismutase'] | 12,092,181 | [['M01.060.057'], ['C05.550.114.122', 'C05.799.056', 'C17.300.775.049', 'C20.111.198'], ['D23.101'], ['D08.811.682.732.332'], ['M01.060.406'], ['M01.060.406.448'], ['D08.811.682.732.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Radioadaptation in Indian muntjac fibroblast cells induced by low intensity laser irradiation. | Earlier reports have indicated that an adaptive, protective response to ionizing radiation is inducible by pre-treatment with low intensity laser irradiation (LILI). We have investigated the potential of LILI to induce an adaptive response against the damaging effects of ionizing radiation in Indian muntjac fibroblasts... | ['Animals', 'Cell Cycle', 'Cell Survival', 'Cells, Cultured', 'Chromosome Aberrations', 'Comet Assay', 'DNA Damage', 'Deer', 'Dose-Response Relationship, Radiation', 'Fibroblasts', 'Lasers', 'Okadaic Acid', 'Radiation Tolerance'] | 10,526,215 | [['B01.050'], ['G04.144'], ['G04.346'], ['A11.251'], ['C23.550.210', 'G05.365.590.175'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.940.560.150'], ['G05.200'], ['B01.050.150.900.649.313.500.380.373'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.81... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Research on the methods for inter-class distinctive feature selection for leucocyte recognition based on attribute hierarchical relationship]. | To increase efficiency of automated leucocyte pattern recognition using lower feature dimensions, a novel inter-class distinctive feature selection method for chromatic leucocyte images was proposed based on attribute hierarchical relationship. According to the attribute constraints in formal concept analysis, we estab... | ['Humans', 'Leukocytes', 'Pattern Recognition, Automated'] | 25,868,230 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637', 'A15.145.229.637', 'A15.382.490'], ['L01.399.750']] | ['Organisms [B]', 'Anatomy [A]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Characterization of ent-kaurene synthase and kaurene oxidase involved in gibberellin biosynthesis from Scoparia dulcis. | Gibberellins (GAs) are ubiquitous diterpenoids in higher plants, whereas some higher plants produce unique species-specific diterpenoids. In GA biosynthesis, ent-kaurene synthase (KS) and ent-kaurene oxidase (KO) are key players which catalyze early step(s) of the cyclization and oxidation reactions. We have studied th... | ['Alkyl and Aryl Transferases', 'Cytochrome P-450 Enzyme System', 'Gibberellins', 'Plant Proteins', 'Scoparia'] | 29,340,903 | [['D08.811.913.225'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['D02.455.849.291.239.500'], ['D12.776.765'], ['B01.650.940.800.575.912.250.583.700.850']] | ['Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
MLC results among unrelated can be predicted. | Typing for LD determinants which has been practicable for some time is shown to be very predictive for the MLC response between unrelated, since LD identical individuals-selected and paired solely on the basis of LD typing-mutually show very low or no MLC reaction. | ['Female', 'Genotype', 'HLA Antigens', 'Haploidy', 'Histocompatibility Antigens', 'Homozygote', 'Humans', 'Lymphocyte Culture Test, Mixed', 'Lymphocytes', 'Male'] | 125,470 | [['G05.380'], ['D23.050.301.500.450', 'D23.050.705.552.450'], ['G05.700.456'], ['D23.050.301.500', 'D23.050.705.552'], ['G05.380.554'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.385.475', 'E05.200.812.385.475', 'E05.478.594.385.429'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nanofluidic redox cycling amplification for the selective detection of catechol. | We have developed a chip-based nanofluidic device to amplify the electrochemical signal of catechols by orders of magnitude. The amplification is based on rapid redox cycling between plane parallel electrodes inside a nanochannel. We show that it is possible to monitor the signal of only a few hundred molecules residin... | ['Ascorbic Acid', 'Biosensing Techniques', 'Catecholamines', 'Catechols', 'Electrochemistry', 'Electrodes', 'Microfluidic Analytical Techniques', 'Oxidation-Reduction', 'Sensitivity and Specificity', 'Silver', 'Silver Compounds'] | 18,193,890 | [['D02.241.081.844.107', 'D02.241.511.902.107', 'D09.811.100'], ['E05.601.043'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['D02.455.426.559.389.657.166'], ['H01.181.529.307'], ['E07.305.250'], ['E05.588.465'], ['G02.700', 'G03.295.531'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Syntheses, crystal structures and antimicrobial activities of 6-coordinate antimony(III) complexes with tridentate 2-acetylpyridine thiosemicarbazone, bis(thiosemicarbazone) and semicarbazone ligands. | Five novel antimony(III) complexes with the mono- and bis(thiosemicarbazone) ligands of 2N1S or 4N2S donor atoms, N'-[1-(2-pyridyl)ethylidene]morpholine-4-carbothiohydrazide (Hmtsc, L1) and bis[N'-[1-(2-pyridyl)ethylidene]]-1,4-piperazinedicarbothiohydrazide (H(2)ptsc, L7), and the tridentate semicarbazone ligand of 2N... | ['Anti-Infective Agents', 'Antimony', 'Crystallography, X-Ray', 'Ligands', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Semicarbazones', 'Spectrophotometry, Infrared'] | 16,546,259 | [['D27.505.954.122'], ['D01.268.513.124', 'D01.268.556.050', 'D01.552.544.050'], ['E05.196.309.742.225'], ['D27.720.470.480'], ['E05.196.867.519'], ['E05.599.595'], ['D02.845.746'], ['E05.196.712.726.676', 'E05.196.867.826.676']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of anti-E6 pegylated lipoplexes for mucosal application in the context of cervical preneoplastic lesions. | Cervical cancer induced by human papillomavirus (HPV) is the fourth highest mortality causing cancer in women despite the use of prophylactic vaccines. E6 targeting represents an attractive strategy to treat this cancer. Indeed, oncoprotein E6 is produced by keratinocytes infected by HPV and is partially responsible fo... | ['Cations', 'Cell Survival', 'Cervical Intraepithelial Neoplasia', 'Cervix Mucus', 'DNA-Binding Proteins', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Liposomes', 'Oncogene Proteins, Viral', 'RNA, Messenger', 'RNA, Small Interfering', 'Structure-Activity Relationship', 'Tumor Cells, Cultured', 'Tumor Suppr... | 25,701,628 | [['D01.248.497.300'], ['G04.346'], ['C04.557.470.200.240.250'], ['A12.200.503.339'], ['D12.776.260'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['D12.776.624.664.520', 'D12.776.964.700'], ['D... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Orthosiphon stamineus Extracts Inhibits Proliferation and Induces Apoptosis in Uterine Fibroid Cells | Objectives: The effects of water and 50% ethanolic-water extracts of Orthosiphon stamineus Benth (OS) on cell
proliferation and apoptotic activity against uterine leiomyosarcoma (SK-UT-1) cells were investigated. Methods:
Anti-proliferation effect was evaluated through cell cycle analysis whereas apoptotic activity was... | ['Apoptosis', 'Cell Cycle Checkpoints', 'Cell Line', 'Cell Proliferation', 'Down-Regulation', 'Female', 'Humans', 'Leiomyoma', 'Leiomyosarcoma', 'Orthosiphon', 'Plant Extracts', 'Proto-Oncogene Proteins c-bcl-2', 'Uterine Neoplasms'] | 30,360,599 | [['G04.146.954.035'], ['G04.144.109'], ['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.590.450'], ['C04.557.450.590.455', 'C04.557.450.795.455'], ['B01.650.940.800.575.912.250.583.520.729'], ['D20.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The detection of rubella-specific IgM by an immunosorbent assay with solid-phase attachment of red cells (SPARC). | An immunosorbent assay using solid-phase attachment of red cells (SPARC) was used for the detection of rubella-specific IgM. The method is described and the results compared with those obtained by the IgM antibody capture radioimmunoassay (MACRIA). One hundred and ninety-nine sera were investigated for the presence of ... | ['Antibodies, Viral', 'Evaluation Studies as Topic', 'Humans', 'Immunoglobulin G', 'Immunoglobulin M', 'Immunosorbent Techniques', 'Radioimmunoassay', 'Rheumatoid Factor', 'Rubella virus'] | 7,045,216 | [['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['D12.776.124.486.485.114.619.574', ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Pathogenesis of central mechanisms of speech function disorders in children with alalia]. | A study of special synchronization of brain biopotentials in EEG registrations by a correlational analysis permitted to establish that in children with alalia there was a complex defect in intercentral relations of the associative infraparietal areas with auditory, visual and motor analyzers in the left hemisphere. In ... | ['Brain Mapping', 'Cerebral Cortex', 'Child, Preschool', 'Cortical Synchronization', 'Electroencephalography', 'Humans', 'Speech Disorders'] | 998,102 | [['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['M01.060.406.448'], ['E01.370.376.300.437.500', 'E01.370.405.245.575.500', 'G07.265.256.249'], ['E01.370.376.300', 'E01.370.405.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.150.500.800'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Parish nursing: nurturing body, mind, spirit, and community. | Parish nursing is a model of nursing care that focuses on health promotion and disease prevention within a faith community. A descriptive study was conducted in the intermountain West to determine how faith communities form parish nursing programs and what their effect is. Thirteen congregations representing eight deno... | ['Cooperative Behavior', 'Health Promotion', 'Health Services Research', 'Holistic Nursing', 'Humans', 'Idaho', 'Preventive Health Services', 'Religion and Medicine', 'Spirituality'] | 12,588,425 | [['F01.145.813.115'], ['I02.233.332.445', 'N02.421.726.407.579'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['H02.478.676.313', 'K01.752.712.708', 'N02.421.533.282'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.560.380'], ['N02.421.726'], ['K01.844.619'], ['F02.880.705', 'K01.844.664.500... | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Humanities [K]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Atypical Clinical Presentation of Xeroderma Pigmentosum in a Patient Harboring a Novel Missense Mutation in the XPC Gene: The Importance of Clinical Suspicion. | BACKGROUND: Xeroderma pigmentosum (XP) is a genodermatosis caused by abnormal DNA repair. XP complementation group C (XPC) is the most frequent type in Mediterranean countries. We describe a case with a novel mutation in the XPC gene.CASE: A healthy Caucasian male patient was diagnosed with multiple primary melanomas. ... | ['Adult', 'DNA Mutational Analysis', 'DNA, Neoplasm', 'DNA-Binding Proteins', 'Dermoscopy', 'Diagnosis, Differential', 'Follow-Up Studies', 'Humans', 'Male', 'Microscopy, Confocal', 'Mutation, Missense', 'Xeroderma Pigmentosum'] | 26,278,556 | [['M01.060.116'], ['E05.393.760.700.300'], ['D13.444.308.425'], ['D12.776.260'], ['E01.370.350.515.277.250', 'E05.595.185.250'], ['E01.171'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.395', 'E05.595.395']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Chronic toxic effects of aluminum on nervous system in rabbits]. | Twenty-one male rabbits were administered with alum (aluminum potassium sulfate) for 32 weeks to study the accumulative toxic effects of aluminum in food additives on central nervous system. Results showed aluminum levels in blood and brain tissue of the animals increased significantly with intake of alum (P < 0.01). B... | ['Alum Compounds', 'Aluminum', 'Animals', 'Brain', 'Male', 'Rabbits', 'Spinal Cord'] | 7,842,872 | [['D01.056.025', 'D01.875.800.800.850.025'], ['D01.268.557.050', 'D01.552.547.050'], ['B01.050'], ['A08.186.211'], ['B01.050.150.900.649.313.968.700'], ['A08.186.854']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Scalable asymmetric total syntheses of (+)-Psoracorylifol B and (+)-ent-Psoracorylifol C. | The first, asymmetric total syntheses of potent antimicrobial Psoracorylifol B (>1.3 g obtained, dr 10.5:1) with a 9.4% overall yield on a gram scale in 14 steps and ent-Psoracorylifol C with a 4.3% yield in 16 steps were achieved. The key features of our synthesis include (i) sequential, rarely explored Achmatowicz re... | ['Anti-Infective Agents', 'Bridged Bicyclo Compounds, Heterocyclic', 'Crystallography, X-Ray', 'Cyclization', 'Magnetic Resonance Spectroscopy', 'Molecular Structure'] | 24,819,702 | [['D27.505.954.122'], ['D03.605.084'], ['E05.196.309.742.225'], ['G02.111.180', 'G02.607.133', 'G03.208'], ['E05.196.867.519'], ['G02.111.570', 'G02.466']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Microfludic platforms for the evaluation of anti-platelet agent efficacy under hyper-shear conditions associated with ventricular assist devices. | Thrombus formation is a major adverse event affecting patients implanted with ventricular assist devices (VADs). Despite anti-thrombotic drug administration, thrombotic events remain frequent within the first year post-implantation. Platelet activation (PA) is an essential process underling thrombotic adverse events in... | ['Adenosine', 'Aspirin', 'Drug Evaluation, Preclinical', 'Heart-Assist Devices', 'Lab-On-A-Chip Devices', 'Platelet Aggregation Inhibitors', 'Shear Strength', 'Sonication', 'Ticagrelor'] | 28,869,117 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['D02.455.426.559.389.657.410.595.176'], ['E05.290.750', 'E05.337.550'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['E07.305.343.500'], ['D27.505.954.502.780'], ['G01.374.820'], ['E05.848'], ['D03.633.100.759.590.138.806', 'D13.570.583... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Confocal laser scanning microscopy using dialkylcarbocyanine dyes for cell tracing in hard and soft biomaterials. | The aim of this work was to study, in vitro, cell colonization of two biomaterials currently used for bone and cartilage repair, this step being important to understand the function of engineered tissues. Current methods that use histological approaches are not always suited to tissue-engineering analysis. We, therefor... | ['Animals', 'Biocompatible Materials', 'Bone Substitutes', 'Carbocyanines', 'Cartilage', 'Cattle', 'Ceramics', 'Chondrocytes', 'Collagen', 'Fibroblasts', 'Fluorescent Dyes', 'Hardness', 'Humans', 'Materials Testing', 'Microscopy, Confocal'] | 16,924,608 | [['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D25.130.325', 'J01.637.051.130.325'], ['D02.455.326.397.300'], ['A02.165', 'A10.165.382'], ['B01.050.150.900.649.313.500.380.271'], ['J01.637.153'], ['A11.329.171'], ['D05.750.078.280', 'D12.776.860.300.250'], ['A11.329.228'], ['D27.720.233.348', 'D27.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Biliverdin reductase: a major physiologic cytoprotectant. | Bilirubin, an abundant pigment that causes jaundice, has long lacked any clear physiologic role. It arises from enzymatic reduction by biliverdin reductase of biliverdin, a product of heme oxygenase activity. Bilirubin is a potent antioxidant that we show can protect cells from a 10,000-fold excess of H2O2. We report t... | ['Antioxidants', 'Bilirubin', 'Biliverdine', 'Glutathione', 'HeLa Cells', 'Heme Oxygenase (Decyclizing)', 'Humans', 'Hydrogen Peroxide', 'Models, Biological', 'Oligonucleotide Array Sequence Analysis', 'Oxidation-Reduction', 'Oxidoreductases', 'Oxidoreductases Acting on CH-CH Group Donors', 'RNA Interference', 'Reactiv... | 12,456,881 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['D03.383.129.578.840.249.184.200', 'D03.633.400.909.249.184.200', 'D04.345.783.249.184.200', 'D23.767.193.184.200'], ['D12.644.456.448'], ['A11.251.210.1... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Global venous function correlates better than duplex derived reflux to clinical class in the evaluation of chronic venous disease. | AIM: To compare the symptoms and signs of patients with chronic venous disease with the objective results of duplex ultrasound and plethysmography (foot volumetry).METHODS: One hundred and one patients with symptomatic chronic venous disease were investigated with duplex ultrasound and foot volumetry. Patients were cla... | ['Adult', 'Aged', 'Chronic Disease', 'Female', 'Femoral Vein', 'Foot', 'Humans', 'Male', 'Middle Aged', 'Plethysmography', 'Popliteal Vein', 'Saphenous Vein', 'Severity of Illness Index', 'Statistics as Topic', 'Sweden', 'Ultrasonography, Doppler, Duplex', 'Venous Insufficiency'] | 12,865,884 | [['M01.060.116'], ['M01.060.116.100'], ['C23.550.291.500'], ['A07.015.908.314'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.370.610'], ['A07.015.908.641'], ['A07.015.908.819'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.5... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Lifespan changes in working memory in fragile X premutation males. | Fragile X syndrome is the world's most common hereditary cause of developmental delay in males and is now well characterized at the biological, brain and cognitive levels. The disorder is caused by the silencing of a single gene on the X chromosome, the FMR1 gene. The premutation (carrier) status, however, is less well... | ['Adolescent', 'Adult', 'Aged', 'Aging', 'Fragile X Mental Retardation Protein', 'Fragile X Syndrome', 'Heterozygote', 'Humans', 'Intelligence Tests', 'Linear Models', 'Male', 'Memory, Short-Term', 'Middle Aged', 'Neuropsychological Tests', 'Principal Component Analysis', 'Surveys and Questionnaires', 'Trinucleotide Re... | 19,114,290 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['D12.776.157.725.061', 'D12.776.631.299', 'D12.776.664.962.124'], ['C10.597.606.360.455.500', 'C16.131.260.830.300', 'C16.320.180.830.300', 'C16.320.322.500.500', 'C16.320.400.525.500'], ['G05.380.383'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The formate channel FocA exports the products of mixed-acid fermentation. | Formate is a major metabolite in the anaerobic fermentation of glucose by many enterobacteria. It is translocated across cellular membranes by the pentameric ion channel/transporter FocA that, together with the nitrite channel NirC, forms the formate/nitrite transporter (FNT) family of membrane transport proteins. Here... | ['Anions', 'Bacterial Proteins', 'Biological Transport', 'Electric Conductivity', 'Fermentation', 'Formates', 'Hydrogen-Ion Concentration', 'Ion Channel Gating', 'Ion Channels', 'Lipid Bilayers', 'Membrane Potentials', 'Salmonella typhimurium'] | 22,847,446 | [['D01.248.497.158'], ['D12.776.097'], ['G03.143'], ['G01.358.500.249.277'], ['G02.111.158.249', 'G03.191.249'], ['D02.241.081.420'], ['G02.300'], ['G02.111.820.400', 'G04.835.400', 'G07.265.625'], ['D12.776.157.530.400', 'D12.776.543.550.450', 'D12.776.543.585.400'], ['D10.570.510', 'J01.637.087.500.510'], ['G01.154.5... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Adaptability - building an academic workforce with GPs. | The University of Wollongong Graduate School of Medicine (UWGSM) opened in 2007. This is one of a new wave of medical schools to enable the more than doubling of the number of medical students graduating in the period from 2006-2014. However, this rapid expansion has exposed a relative paucity of experienced medical ac... | ['Education, Medical', 'Faculty, Medical', 'General Practitioners', 'Humans', 'New South Wales', 'Physicians, Women', 'Schools, Medical', 'Students, Medical', 'Teaching', 'Workforce'] | 21,301,685 | [['I02.358.399'], ['M01.526.485.375', 'M01.526.702.250.373', 'N02.360.375'], ['M01.526.485.810.485', 'N02.360.810.485'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.639.100.750', 'Z01.678.100.373.750'], ['M01.526.485.810.820', 'M01.975.790', 'N02.360.810.820'], ['I02.783.495.552', 'N02.278.020.578'], ['M01.8... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Positive Illusions? The Accuracy of Academic Self-Appraisals in Adolescents With ADHD. | OBJECTIVE: Children with attention deficit/hyperactivity disorder (ADHD) overestimate their academic competencies (AC) relative to performance and informant indicators (i.e., positive illusory bias; PIB). Do adolescents with ADHD exhibit this PIB and does it render self-views inaccurate? We examined the magnitude of th... | ['Achievement', 'Adolescent', 'Aptitude', 'Attention Deficit Disorder with Hyperactivity', 'Case-Control Studies', 'Executive Function', 'Female', 'Humans', 'Illusions', 'Male', 'Parents', 'Self Concept', 'Self Report', 'Self-Assessment'] | 26,645,302 | [['F01.658.059', 'F02.784.629.054'], ['M01.060.057'], ['F02.784.629.131'], ['F03.625.094.150'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.762.400', 'C23.888.592.604.764.400', 'F01.700.750.400', 'F02.463.... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Influence of exogenous interleukin-2 concentration on the isolation of human immunodeficiency virus. | A significant increase (P = 0.015) in the HIV isolation rate from plasma samples was achieved by use of 10 U/ml exogenous interleukin-2 compared to 20 U/ml. The sensitivity rose from 0% to 29% in patients negative for p24 core antigen (P = 0.031) and from 71% to 86% in patients positive for p24 core antigen in plasma (... | ['Acquired Immunodeficiency Syndrome', 'Cells, Cultured', 'DNA, Viral', 'Enzyme-Linked Immunosorbent Assay', 'Flow Cytometry', 'HIV Core Protein p24', 'HIV Infections', 'HIV-1', 'Humans', 'Interleukin-2', 'Leukocytes, Mononuclear', 'Microbiological Techniques', 'Polymerase Chain Reaction', 'Sensitivity and Specificity'... | 7,783,684 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['A11.251'], ['D13.444.308.568'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], [... | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of arteriovenous fistulas on cardiac oxygen supply and demand. | BACKGROUND: Arteriovenous (AV) fistulas used for hemodialysis access may affect cardiac load by increasing the preload while decreasing the afterload. In dogs, AV fistulas have also been shown to affect coronary perfusion negatively. We investigated the net effect of AV fistulas on cardiac oxygen supply and demand.METH... | ['Adult', 'Aged', 'Arteriovenous Shunt, Surgical', 'Coronary Circulation', 'Female', 'Heart', 'Heart Rate', 'Humans', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Oxygen Consumption', 'Stroke Volume', 'Vascular Resistance'] | 10,231,470 | [['M01.060.116'], ['M01.060.116.100'], ['E04.035.087', 'E04.100.814.868.249'], ['G09.330.100.324'], ['A07.541'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['M01.060.116.630'], ['G03.680'], ['E01.370.370.380.15... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Tibolone's effect on retinal and ophthalmic arteries flowmetry]. | PURPOSE: to evaluate the effect of tibolone use on doppler-velocimetric parameters of ophthalmic and retinal arteries.METHODS: clinical, prospective, longitudinal, randomized, placebo-controlled, triple-blind study, in which among 100 menopausal women, 50 have used 2.5 mg of the active principle tibolone (Tib Group) an... | ['Double-Blind Method', 'Estrogen Receptor Modulators', 'Female', 'Humans', 'Laser-Doppler Flowmetry', 'Middle Aged', 'Norpregnenes', 'Ophthalmic Artery', 'Prospective Studies', 'Retinal Artery'] | 19,148,430 | [['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D06.347.360', 'D27.505.696.399.450.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.370.475', 'E05.830.500'], ['M01.060.116.630'], ['D04.210.500.668.651.693'], ['A07.015.114.622'], ['E05.318.372.500.750.625', 'N05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bimanual coordination and corpus callosum microstructure in young adults with traumatic brain injury: a diffusion tensor imaging study. | Bimanual actions are ubiquitous in daily life. Many coordinated movements of the upper extremities rely on precise timing, which requires efficient interhemispheric communication via the corpus callosum (CC). As the CC in particular is known to be vulnerable to traumatic brain injury (TBI), furthering our understanding... | ['Adolescent', 'Adult', 'Brain Injuries', 'Cohort Studies', 'Corpus Callosum', 'Diffusion Tensor Imaging', 'Female', 'Functional Laterality', 'Humans', 'Male', 'Motor Skills', 'Movement Disorders', 'Young Adult'] | 21,501,046 | [['M01.060.057'], ['M01.060.116'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['A08.186.211.200.885.800.750'], ['E01.370.350.578.750', 'E01.370.350.825.500.150.500', 'E01.370.376.537.500', 'E05.629.750'], ['F02.830.297.425', ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Henoch-Sch?nlein purpura: a case with atypical presentation. | We report on a case of Henoch-Sch?nlein purpura (HSP) with pulmonary hemorrhage and severe renal involvement. The patient also had active carditis related to acute rheumatic fever. He died despite intensive treatment. Regarding this case, we discuss the pathogenesis and clinical findings of pulmonary hemorrhage and act... | ['Adolescent', 'Hemorrhage', 'Humans', 'Immunoglobulin A', 'Lung Diseases', 'Male', 'Myocarditis', 'Purpura, Schoenlein-Henoch', 'Streptococcal Infections', 'Streptococcus pyogenes'] | 16,180,001 | [['M01.060.057'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.790.651.114.619.026', 'D12.776.377.715.548.114.619.026'], ['C08.381'], ['C14.280.238.625'], ['C14.907.940.777', 'C15.378.100.802.375', 'C15.378.463.515.580', 'C20.543.520.600', 'C23.550.4... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Division of stellate reticulocytes in rat liver following vagotomy]. | The authors studied the 24-hour variations of mitoses in the stellate reticuloendothelial intralobular blood capillaries of rats under normal conditions and after bilateral subphrenic vagotomy. The greatest number of mitoses was noted in all the animals in the morning hours--3 to 7 a.m. A gradual decrease in the number... | ['Animals', 'Capillaries', 'Circadian Rhythm', 'Laparotomy', 'Liver', 'Mitosis', 'Mononuclear Phagocyte System', 'Rats', 'Vagotomy'] | 884,305 | [['B01.050'], ['A07.015.461.165'], ['G07.180.562.190'], ['E04.406'], ['A03.620'], ['G04.144.220.220.781', 'G05.113.220.781'], ['A15.382.670'], ['B01.050.150.900.649.313.992.635.505.700'], ['E04.525.210.105.600.850']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endovascular stent graft repair of thoracic aortic mural thrombus in a patient with polycythemia vera: a word of caution. | Thoracic aortic mural thrombus (TAMT) is a rare pathology and potential source of cerebral, visceral, and peripheral emboli. We present a 62-year-old male in a hypercoagulable state due to primary polycythemia vera (PV) developed TAMT and catastrophic thromboembolisms despite aggressive medical and surgical management.... | ['Aorta, Thoracic', 'Aortic Diseases', 'Aortography', 'Blood Coagulation', 'Blood Vessel Prosthesis', 'Blood Vessel Prosthesis Implantation', 'Echocardiography, Transesophageal', 'Endovascular Procedures', 'Humans', 'Male', 'Middle Aged', 'Polycythemia Vera', 'Risk Assessment', 'Risk Factors', 'Thromboembolism', 'Throm... | 24,569,113 | [['A07.015.114.056.372'], ['C14.907.109'], ['E01.370.350.700.060.070', 'E01.370.370.050.070'], ['G09.188.390.150'], ['E07.695.110'], ['E04.100.814.868.500', 'E04.650.200'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['E04.100.814.529', 'E04.502.382'], ['B01.050.150.900.649.313.98... | ['Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comprehensive assessment the expression of core elements related to IGFIR/PI3K pathway in granulosa cells of women with polycystic ovary syndrome. | OBJECTIVE: Polycystic ovary syndrome (PCOS) is the most common multisystem endocrinopathy in women, characterized by chronic hyperandrogenism, ovulatory dysfunction, and polycystic ovaries. But its etiology remains elusive. A plethora of information suggests phosphatidylinositol-3-kinase (PI3K) pathway is key to the pa... | ['Adult', 'Blotting, Western', 'Case-Control Studies', 'Female', 'Follicular Fluid', 'Gene Expression', 'Granulosa Cells', 'Humans', 'Ovulation Induction', 'Phosphatidylinositol 3-Kinases', 'Polycystic Ovary Syndrome', 'RNA, Messenger', 'Receptor, IGF Type 1', 'Receptors, Somatomedin', 'Reverse Transcriptase Polymerase... | 30,594,023 | [['M01.060.116'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A05.360.319.114.630.535.150', 'A06.300.312.497.535.150', 'A12.207.270.340'], ['G05.297'], ['A05.360.319.114.630.535.200'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Increased frequency of micronuclei in immature seminal germinal cells of male workers exposed to aromatic hydrocarbons. | The aim of the present work was to investigate whether there is an association between the presence of micronuclei in immature seminal germinal cells and occupational exposure to aromatic hydrocarbons in the workplace. We concluded that exposure of the workers to hydrocarbons in their workplace increased the frequency ... | ['Adult', 'Air Pollutants, Occupational', 'Humans', 'Hydrocarbons, Aromatic', 'Male', 'Micronuclei, Chromosome-Defective', 'Occupational Exposure', 'Spermatozoa', 'Statistics, Nonparametric'] | 16,169,433 | [['M01.060.116'], ['D27.888.284.101.268'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559'], ['A11.284.430.106.570', 'A11.284.430.214.190.875.117.570', 'C23.550.210.570', 'G05.365.590.175.570'], ['N06.850.460.350.600'], ['A05.360.490.890', 'A11.497.760'], ['E05.318.740.995', 'N05.715.360.750.760', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The Use of Peripherally Inserted Central Catheter in Amyotrophic Lateral Sclerosis Patients at a Later Stage. | BACKGROUND/AIMS: To describe the use of peripherally inserted central catheter (PICC), in amyotrophic lateral sclerosis (ALS) at a later stage.METHODS: Twenty-five ALS patients in the later stages of the disease underwent PICC insertion followed by parenteral nutrition (PN). For all of them, gastrostomy was non-feasibl... | ['Adult', 'Amyotrophic Lateral Sclerosis', 'Catheterization, Central Venous', 'Catheterization, Peripheral', 'Female', 'Humans', 'Male', 'Middle Aged', 'Parenteral Nutrition'] | 27,978,519 | [['M01.060.116'], ['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['E02.148.224', 'E04.100.814.529.937', 'E04.502.382.937', 'E05.157.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Influence of axial deformities on the LDH isoenzyme of cartilage and synovial membrane in gonarthrosis]. | Varus or valgus deformities and metabolic alterations of the articular cartilage and synovialis of patients with gonarthrosis (n = 67) had been analysed. The increase of axial deviation went together with a significant change of the LDH-activity of the cartilage. The increasing activity of the LDHH-subunits depending o... | ['Aged', 'Cartilage, Articular', 'Female', 'Humans', 'Isoenzymes', 'Knee Joint', 'L-Lactate Dehydrogenase', 'Male', 'Middle Aged', 'Osteoarthritis', 'Stress, Physiological', 'Synovial Membrane'] | 6,649,923 | [['M01.060.116.100'], ['A02.165.407.150', 'A02.835.583.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.348', 'D12.776.800.300'], ['A02.835.583.475'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['M01.060.116.630'], ['C05.550.114.606', 'C05.799.613'], ['G07.775'], ['A02.835.583.443.800']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Prevention of the development of spontaneous hypertension in rats by captopril (SQ 14,225). | Indirect systolic blood pressure (SBP) was monitored in male, weanling, spontaneously hypertensive rats (SHR) maintained on water for 16 weeks (group A) or on captopril therapy (100 mg/kg/day in drinking water) for 4 (group B), 8 (group C), 12 (group D), 16 (group E) weeks. Weanling SHR of group A developed typical, ti... | ['Animals', 'Blood Pressure', 'Body Weight', 'Captopril', 'Drinking Behavior', 'Heart Rate', 'Hypertension', 'Male', 'Proline', 'Rats', 'Time Factors'] | 393,524 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
3D correlative electron microscopy reveals continuity of Brucella | Entry of the facultative intracellular pathogen Brucella into host cells results in the formation of endosomal Brucella-containing vacuoles (eBCVs) that initially traffic along the endocytic pathway. eBCV acidification triggers the expression of a type IV secretion system that translocates bacterial effector proteins i... | ['Animals', 'Brucella abortus', 'Brucella melitensis', 'Cytoplasm', 'Endoplasmic Reticulum', 'HeLa Cells', 'Host-Pathogen Interactions', 'Humans', 'Mice', 'Microscopy, Electron, Scanning', 'Trophoblasts', 'Type IV Secretion Systems', 'Vacuoles'] | 29,361,547 | [['B01.050'], ['B03.440.400.425.215.500.100', 'B03.660.050.070.100.100'], ['B03.440.400.425.215.500.500', 'B03.660.050.070.100.500'], ['A11.284.430.214'], ['A11.284.430.214.190.875.248'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['G06.462', 'G16.527.200'], ['B01.050.150.900.649.313.988.400.112.400... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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