Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
The effects of indomethacin on refractoriness following exercise both with and without a bronchoconstrictor response. | Repeated exercise tests demonstrate refractoriness to the development of exercise-induced asthma (EIA). It is unclear whether it is the initial exercise per se or the resulting bronchoconstriction that causes the attenuated response to the second exercise challenge. This study was designed to determine whether the repo... | ['Adolescent', 'Asthma, Exercise-Induced', 'Bronchoconstriction', 'Double-Blind Method', 'Exercise Test', 'Female', 'Forced Expiratory Volume', 'Hot Temperature', 'Humans', 'Humidity', 'Indomethacin', 'Male', 'Premedication', 'Prostaglandins', 'Reproducibility of Results'] | 7,713,200 | [['M01.060.057'], ['C08.127.108.110', 'C08.674.095.110', 'C20.543.480.680.095.110'], ['G09.772.705.700.080'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['G01.906.595... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A role for clonal inactivation in T cell tolerance to Mls-1a. | Clonal deletion plays a major part in the maintenance of natural self-tolerance in both normal and transgenic mice. Self antigens that are expressed in the thymus result in the physical elimination of autoreactive thymocytes at a particular stage in their development. For example, the majority V beta 6- and V beta 8.1-... | ['Animals', 'Autoantigens', 'CD4-Positive T-Lymphocytes', 'Clone Cells', 'Immune Tolerance', 'Mice', 'Mice, Transgenic', 'Minor Histocompatibility Loci', 'Receptors, Antigen, T-Cell', 'Receptors, Antigen, T-Cell, alpha-beta', 'T-Lymphocytes', 'Thymus Gland'] | 1,971,916 | [['B01.050'], ['D23.050.422'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.251.353'], ['G12.535.425'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['G05.360.340.024.380.625', 'G12.500.53... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Smell impairment in chronic rhinosinusitis – evaluation of endoscopic sinus surgery results and review of literature concerning olfactory function predictors. | INTRODUCTION: Endoscopic sinus surgery (ESS) is the treatment of choice for patients with chronic rhinosinusitis (CRS) refractory to medical therapy. ESS successfully reduces most symptoms of CRS, but its effect on olfaction is always uncertain.AIM OF THE STUDY: The aim of this study was to assess the influence of sinu... | ['Chronic Disease', 'Endoscopy', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Olfaction Disorders', 'Otorhinolaryngologic Surgical Procedures', 'Recovery of Function', 'Rhinitis', 'Sinusitis', 'Smell', 'Treatment Outcome'] | 25,753,166 | [['C23.550.291.500'], ['E01.370.388.250', 'E04.502.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.751.600', 'C23.888.592.763.550'], ['E04.580'], ['G16.757'], ['C01.748.674', 'C08.460.799', 'C08.730.674', 'C09.6... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Blood coagulation and fibrinolysis after confinement hypokinesia. | Our previous studies dealt with the dynamics of the fluid-coagulant equilibrium in rats after confinement hypokinesia (CHK) for 1, 2 and 3 weeks obtained by placing them in small cages permitting only slight movements for spontaneous feeding. We found an acceleration of blood coagulation and fibrinolysis, with a maxima... | ['Adrenal Glands', 'Adrenalectomy', 'Animals', 'Blood Coagulation', 'Corticosterone', 'Fibrinolysis', 'Platelet Count', 'Rats', 'Restraint, Physical', 'Stress, Physiological', 'Time Factors'] | 3,148,938 | [['A06.300.071'], ['E04.270.115'], ['B01.050'], ['G09.188.390.150'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['G09.188.390.150.390'], ['E01.370.225.500.195.107.740', 'E01.370.225.625.107.700', 'E01.370.225.625.625.625', 'E05.200.500.195.107.740', 'E05.200.625.107.700', 'E05.200.625.625.625', 'E05.24... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The virulence of trimethoprim-resistant thymine-requiring strains of Salmonella. | A thymine-requiring (thy-), trimethoprim-resistant (tmpr) mutant isolated from the faeces of chickens experimentally infected with salmonella typhimurium and treated with mixture of trimethoprim and sulphadiazine was less virulent for chickens than the parent strain and a thy+tmps revertant prepared in vitro from the m... | ['Administration, Oral', 'Animals', 'Chickens', 'Digestive System', 'Drug Resistance, Microbial', 'Feces', 'Injections, Subcutaneous', 'Mice', 'Mutation', 'Salmonella', 'Salmonella typhimurium', 'Thymine', 'Trimethoprim', 'Virulence'] | 1,107,416 | [['E02.319.267.100'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A03'], ['G06.225', 'G07.690.773.984.269'], ['A12.459'], ['E02.319.267.530.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['G05.365.590'], ['B03.440.450.425.800', 'B03.660.250.150.710'], ['B03.440.450.425.800.200.82... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dibutyl phthalate biodegradation by the white rot fungus, Polyporus brumalis. | In this study, white rot fungus, Polyporus brumalis, was applied to degrade dibutyl phthalate (DBP), a major environmental pollutant. The degradation potential and resulting products were evaluated with HPLC and GC/MS. As DBP concentration increased to 250, 750, and 1,250 microM, the mycelial growth of P. brumalis was ... | ['Basidiomycota', 'Biodegradation, Environmental', 'Dibutyl Phthalate'] | 17,221,890 | [['B01.300.179'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D02.241.223.805.225']] | ['Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Generation of a Quantitative Luciferase Reporter for Sox9 SUMOylation. | Sox9 is a master transcription factor for chondrogenesis, which is essential for chondrocyte proliferation, differentiation, and maintenance. Sox9 activity is regulated by multiple layers, including post-translational modifications, such as SUMOylation. A detection method for visualizing the SUMOylation in live cells i... | ['Animals', 'Cell Differentiation', 'Chondrocytes', 'Chondrogenesis', 'Gene Expression Regulation', 'Gene Expression Regulation, Developmental', 'HEK293 Cells', 'Humans', 'Promoter Regions, Genetic', 'SOX9 Transcription Factor', 'SUMO-1 Protein', 'Sumoylation'] | 32,070,068 | [['B01.050'], ['G04.152'], ['A11.329.171'], ['G07.345.500.325.377.625.180', 'G11.427.578.180'], ['G05.308'], ['G05.308.310'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['D12.776.260.719.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quality assurance for care of the dying: engaging with clinical services to facilitate a regional cross-sectional survey of bereaved relatives' views. | BACKGROUND: Globally, having the 'patient and /or family voice' engaged when measuring quality of care for the dying is fundamentally important. This is particularly pertinent within the United Kingdom, where changes to national guidance about care provided to dying patients has heightened the importance of quality ass... | ['Adult', 'Aged', 'Aged, 80 and over', 'Attitude to Health', 'Bereavement', 'Communication', 'Cross-Sectional Studies', 'Family', 'Female', 'Hospice Care', 'Hospitals', 'Humans', 'Male', 'Middle Aged', 'Patient Participation', 'Quality Assurance, Health Care', 'Surveys and Questionnaires', 'Terminal Care', 'United King... | 30,305,082 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.150', 'N05.300.150'], ['F01.470.142'], ['F01.145.209', 'L01.143'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.829.263', 'I01.880.853.150'], ['E02.760.905.400', 'N02.421.585.905.400'], ['N02.278.421'], ['B... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
A tomato chloroplast-targeted DnaJ protein protects Rubisco activity under heat stress. | Photosynthesis is one of the biological processes most sensitive to heat stress in plants. Carbon assimilation, which depends on ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco), is one of the major sites sensitive to heat stress in photosynthesis. In this study, the roles of a tomato (Solanum lycopersicum) ch... | ['Carbon Dioxide', 'Chlorophyll', 'Chloroplasts', 'HSP40 Heat-Shock Proteins', 'HSP70 Heat-Shock Proteins', 'Hot Temperature', 'Lycopersicon esculentum', 'Photosynthesis', 'Plant Leaves', 'Plant Proteins', 'Plants, Genetically Modified', 'Reactive Oxygen Species', 'Ribulose-Bisphosphate Carboxylase', 'Stress, Physiolog... | 25,801,077 | [['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['A11.284.430.214.190.875.700.140'], ['D12.776.580.216.292'], ['D12.776.580.216.375'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Antioxidant effectiveness as influenced by phenolic content of fresh orange juices. | Several fresh orange juices, obtained from five different Citrus sinensis (L.) Osbeck varieties (three pigmented varieties, Moro, Sanguinello, and Tarocco, and two blond varieties, Valencia late and Washington navel), were subjected to antioxidant profile determination (including total polyphenols, flavanones, anthocya... | ['Antioxidants', 'Beverages', 'Free Radicals', 'Fruit', 'Phenols', 'Regression Analysis'] | 10,552,879 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G07.203.100', 'J02.200'], ['D01.339', 'D02.389'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['D02.455.426.559.389.657'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Leukemic pneumonitis as a poor prognostic factor in chronic myelomonocytic leukemia. | We report the case of a 69-year-old man with chronic myelomonocytic leukemia (CMML) that was complicated by fatal respiratory failure. Bilateral pulmonary infiltrates were demonstrated by chest roentgenograms and worsened with an increase in the leukocyte count. Postmortem examination confirmed the presence of leukemic... | ['Aged', 'Humans', 'Leukemia, Myelomonocytic, Chronic', 'Leukocyte Count', 'Male', 'Prognosis', 'Pulmonary Fibrosis'] | 1,620,981 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.522', 'C15.378.190.615.510'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.195.107.595', 'G04.140.107.595', 'G09.188.105.595'], ['E01.789'], ['C08.381.765']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Management and clinical outcomes of transfusion-dependent thalassaemia major in an Australian tertiary referral clinic. | OBJECTIVE: To evaluate the management, clinical outcomes and adherence to chelation therapy in adult transfusion-dependent patients with thalassaemia major.DESIGN, SETTING AND PARTICIPANTS: We reviewed all transfusion-dependent adults with thalassaemia major (n = 44) attending the Haematology Department at the Prince o... | ['Adult', 'Age Factors', 'Australia', 'Cardiomyopathies', 'Deferiprone', 'Deferoxamine', 'Diabetes Mellitus', 'Drug Prescriptions', 'Erythrocyte Transfusion', 'Female', 'Ferritins', 'Hepatitis B', 'Hepatitis C', 'Humans', 'Hypogonadism', 'Hypothyroidism', 'Iron Chelating Agents', 'Male', 'Middle Aged', 'Outcome Assessm... | 18,205,577 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['Z01.639.100', 'Z01.678.100.373'], ['C14.280.238'], ['D03.383.725.791.298'], ['D02.092.570.394.265', 'D02.241.511.372.265'], ['C18.452.394.750', 'C19.246'], ['E02.319.307', 'N02.421.668.778.500'], ['E02.095.135.140.275'], ['D12.776.157.427.249', 'D12.776.556.57... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Comminuted supracondylar humeral fractures repaired with a modified type I external skeletal fixator construct. | Highly comminuted supracondylar humeral fractures were stabilised in six large-breed dogs with a modified type I external fixator using a craniomedial acrylic connecting column and an intramedullary pin which was incorporated into the connecting frame. This construct provided sufficient stability to allow satisfactory ... | ['Animals', 'Bone Nails', 'Dog Diseases', 'Dogs', 'External Fixators', 'Fracture Fixation', 'Humeral Fractures', 'Treatment Outcome', 'Weight-Bearing'] | 9,846,315 | [['B01.050'], ['E07.695.370.249', 'E07.858.442.660.460.249', 'E07.858.690.725.460.249'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['E04.555.300'], ['C26.088.390', 'C26.404.500'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['G01.374... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effectiveness, safety/tolerability of OBV/PTV/r ± DSV in patients with HCV genotype 1 or 4 with/without HIV-1 co-infection, chronic kidney disease (CKD) stage IIIb-V and dialysis in Spanish clinical practice - Vie-KinD study. | BACKGROUND AND AIMS: Limited data are available on the effectiveness and tolerability of direct-acting antivirals (DAAs) therapies in the real world for HCV-infected patients with comorbidities. This study aimed to describe the effectiveness of OBV/PTV/r ± DSV (3D/2D regimen) with or without ribavirin (RBV) in HCV or H... | ['Aged', 'Anilides', 'Antiviral Agents', 'Carbamates', 'Coinfection', 'Drug Therapy, Combination', 'Female', 'Genotype', 'HIV Infections', 'HIV-1', 'Hepacivirus', 'Hepatitis C, Chronic', 'Humans', 'Macrocyclic Compounds', 'Male', 'Middle Aged', 'Renal Dialysis', 'Renal Insufficiency, Chronic', 'Retrospective Studies', ... | 31,550,267 | [['M01.060.116.100'], ['D02.065.199', 'D02.092.146.113'], ['D27.505.954.122.388'], ['D02.241.081.251'], ['C01.218'], ['E02.319.310'], ['G05.380'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B04.820.650.589.650.350.400'], ['B04.450.380', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Propargyl 1,2-orthoesters for a catalytic and stereoselective synthesis of pyrimidine nucleosides. | Pyrimidine nucleosides are synthesized by using propargyl 1,2-orthoesters and Au(III) salt as a catalyst. Strategically positioned 1,2-orthoesters are found to yield only 1,2-trans nucleosides and enable preparation of 2'-OH containing pyrimidine nucleosides. The glycosyl donor employed in this study is stable and easi... | ['Catalysis', 'Esters', 'Pargyline', 'Pyrimidine Nucleosides', 'Stereoisomerism'] | 25,539,179 | [['G02.130'], ['D02.241.400'], ['D02.092.200.650', 'D02.455.426.559.389.140.210.650'], ['D03.383.742.680', 'D13.570.685'], ['G02.607.445.682']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of the protein-coding gene content of Chlamydia trachomatis and Protochlamydia amoebophila using a Raspberry Pi computer. | BACKGROUND: To demonstrate the bioinformatics capabilities of a low-cost computer, the Raspberry Pi, we present a comparison of the protein-coding gene content of two species in phylum Chlamydiae: Chlamydia trachomatis, a common sexually transmitted infection of humans, and Candidatus Protochlamydia amoebophila, a rece... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Chlamydia trachomatis', 'Chlamydiales', 'Computational Biology', 'Exodeoxyribonuclease V', 'Gene Expression', 'Membrane Proteins', 'Microcomputers', 'Molecular Sequence Annotation', 'Molecular Sequence Data', 'Open Reading Frames', 'Protein Interaction Mapping', 'Sequence ... | 26,462,790 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['B03.440.190.190.190.750'], ['B03.440.190'], ['H01.158.273.180', 'L01.313.124'], ['D08.811.277.352.335.375.750'], ['G05.297'], ['D12.776.543'], ['L01.224.230.260.550'], ['E05.393.760.479', 'L01.453.245.667.580'], ['L01.453.245.667'], ['G05.360.335.760.640',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Algal extracellular products suppress Anabaena flos-aquae heterocyst spacing. | Intra- and interspecific chemical signals allow bacteria to respond to environmental conditions by regulating gene transcription. In cyanobacteria, gene products and the presence of fixed nitrogen regulate heterocyst frequency. In this paper, we describe a chemical made by a green alga, Chlamydomonas reinhardtii, that ... | ['Anabaena', 'Animals', 'Chlamydomonas reinhardtii', 'Phenotype', 'Phytoplankton', 'Plant Extracts', 'Population Dynamics', 'Water Microbiology'] | 11,984,639 | [['B03.280.100', 'B03.440.475.100.100', 'B03.585.051'], ['B01.050'], ['B01.650.940.150.385.650'], ['G05.695'], ['B05.080.500.600'], ['D20.215.784.500', 'D26.667'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['H01.158.273.540.274.777', 'N06.850.425.450']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Comparison of acute toxic effects of intraperitoneally injected nitromethane and nitroethane in rats. | Male 3-month-old Wistar rats dosed i.p. with 200 mg/kg of nitromethane or -ethane showed increased acid proteinase activity in the brain 4 h after the injection. The change was accompanied by a marginal increase in the cerebral glutathione concentration. Nitroethane caused enhanced epoxide hydrolase and UDP-glucuronosy... | ['7-Alkoxycoumarin O-Dealkylase', 'Alkanes', 'Animals', 'Brain', 'Ethane', 'Glutathione', 'Injections, Intraperitoneal', 'Liver', 'Male', 'Methane', 'NADPH-Ferrihemoprotein Reductase', 'Nitroparaffins', 'Oxygenases', 'Rats', 'Time Factors'] | 6,815,833 | [['D08.811.682.690.708.170.010.024'], ['D02.455.326.146'], ['B01.050'], ['A08.186.211'], ['D02.455.326.146.379'], ['D12.644.456.448'], ['E02.319.267.530.490'], ['A03.620'], ['D02.455.326.146.571'], ['D08.811.682.608.191.500'], ['D02.455.326.146.672', 'D02.640.720'], ['D08.811.682.690'], ['B01.050.150.900.649.313.992.63... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Agreement of the Resting Distal to Aortic Coronary Pressure With the Instantaneous Wave-Free Ratio. | BACKGROUND: Recently, 2 randomized controlled trials showed that the instantaneous wave-free ratio (iFR), a resting coronary physiological index, is noninferior to fractional flow reserve for guiding revascularization. The resting distal to aortic coronary pressure (Pd/Pa) measured at rest is another adenosine-free ind... | ['Aged', 'Blood Pressure', 'Blood Pressure Determination', 'Coronary Circulation', 'Coronary Vessels', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Reference Standards'] | 29,050,557 | [['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140', 'E01.370.600.100'], ['G09.330.100.324'], ['A07.015.114.269', 'A07.015.908.194'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A case of biliary cystadenocarcinoma arising in the liver with a congenital retention of indocyanine green. | A case of biliary cystadenocarcinoma that occurred in a 45-year-old woman is reported. Ultrasonography and computed tomography clearly revealed papillary projections in the cyst of the liver. Percutaneous transhepatic cystography showed connection between the cyst and the common bile duct. The tumor was surgically rese... | ['Adenocarcinoma, Mucinous', 'Adenocarcinoma, Papillary', 'Biliary Tract Neoplasms', 'Cystadenocarcinoma', 'Female', 'Humans', 'Indocyanine Green', 'Liver Neoplasms', 'Middle Aged', 'Neoplasms, Multiple Primary'] | 1,332,426 | [['C04.557.470.200.025.075', 'C04.557.470.590.075'], ['C04.557.470.200.025.085'], ['C04.588.274.120', 'C06.130.320', 'C06.301.120'], ['C04.557.470.200.025.480', 'C04.557.470.590.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['M01.060.... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Use of a heptane-isopropanol system for extraction of primary lipid peroxidation products]. | Products of different lipids oxidation were studied for the peculiarities of their distribution in the extracting system heptane--isopropanol widely used in spectrophotometric determination of primary products of peroxide oxidation of lipids. It is shown that hydroperoxides of phospholipids and their reduction products... | ['1-Propanol', 'Heptanes', 'Lipid Peroxides'] | 2,028,525 | [['D02.033.755.600'], ['D02.455.326.146.485'], ['D01.248.497.158.685.750.637', 'D01.339.431.374.637', 'D01.650.550.750.600', 'D02.389.338.450', 'D10.440']] | ['Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A cohort study of enfuvirtide immunological and virological efficacy in clinical practice. | The aim of the study was to evaluate, under routine circumstances, the immunological and virological efficacy of antiretroviral regimens containing enfuvirtide in multi-class experienced HIV-1 infected patients. This retrospective monocentric study analyzed the clinical, immunological, and virological data of 18 HIV-1 ... | ['Adult', 'Aged', 'CD4 Lymphocyte Count', 'Cohort Studies', 'Drug Resistance, Viral', 'Enfuvirtide', 'Female', 'HIV Envelope Protein gp41', 'HIV Fusion Inhibitors', 'HIV Infections', 'HIV-1', 'Hospitals, Teaching', 'Humans', 'Male', 'Middle Aged', 'Mutation', 'Peptide Fragments', 'Protein Structure, Tertiary', 'RNA, Vi... | 16,927,284 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.500.150', 'G04.140.107.595.500.150', 'G09.188.105.595.500.150'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Occurrence and distribution of capB in Antarctic microorganisms and study of its structure and regulation in the Antarctic biodegradative Pseudomonas sp. 30/3. | The analysis of the cold-shock domain (CSD)-encoding genes, capB and cspA, by PCR amplification showed presence of capB in all 18 Antarctic Pseudomonas isolates, but the absence of cspA. Nucleotide sequence analysis of capB ORF from a biodegradative Pseudomonas 30/3 and its regulatory sequences including the promoter a... | ["5' Untranslated Regions", 'Acclimatization', 'Amino Acid Sequence', 'Antarctic Regions', 'Bacterial Proteins', 'Base Sequence', 'Carrier Proteins', 'Cold Climate', 'DNA Primers', 'DNA, Bacterial', 'Gene Expression Regulation, Bacterial', 'Genes, Bacterial', 'Heat-Shock Proteins', 'Immunohistochemistry', 'Molecular Se... | 20,091,073 | [['D13.444.735.544.875.885', 'D13.444.735.790.878.885', 'G05.360.340.024.220.880.885', 'G05.360.340.024.340.137.910.885'], ['G07.025.133', 'G16.012.500.133'], ['G02.111.570.060', 'L01.453.245.667.060'], ['Z01.158'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.157'], ['G16.500.2... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
[Severe obstructive sleep apnea-hypopnea syndrome with latent renal dysfunction: analysis of 238 cases]. | OBJECTIVE: To evaluate the association between severity of obstructive sleep apnea hypopnea syndrome (OSAHS) without chronic kidney disease (CKD) and serum cystatin C.METHODS: A total of 238 patients with snoring during sleep admitted between January 2012 and June 2015 underwent full-night polysomnography for diagnosis... | ['Blood Glucose', 'Cystatin C', 'Humans', 'Hypoxia', 'Kidney Diseases', 'Leukocyte Count', 'Polysomnography', 'Sleep', 'Sleep Apnea, Obstructive', 'Snoring', 'Superoxide Dismutase'] | 27,063,159 | [['D09.947.875.359.448.500'], ['D12.776.215.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.079'], ['C12.777.419', 'C13.351.968.419'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.195.107.595', 'G04.140.107.595', 'G09.188.105... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Network analysis of ChIP-Seq data reveals key genes in prostate cancer. | BACKGROUND: Prostate cancer (PC) is the second most common cancer among men in the United States, and it imposes a considerable threat to human health. A deep understanding of its underlying molecular mechanisms is the premise for developing effective targeted therapies. Recently, deep transcriptional sequencing has be... | ['Binding Sites', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Male', 'Prostatic Neoplasms', 'Protein Interaction Maps'] | 25,183,411 | [['G02.111.570.120'], ['E05.393.332'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['G03.493.750']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of microRNA profile in mammary tissue of dairy and beef breed heifers. | MicroRNAs (miRNAs) are small non-coding RNAs that participate in the regulation of gene expression. Their role during mammary gland development is still largely unknown. In this study, we performed a microarray analysis to identify miRNAs associated with high mammogenic potential of the bovine mammary gland. We identif... | ['Animals', 'Cattle', 'Dairying', 'Female', 'Mammary Glands, Animal', 'MicroRNAs', 'Polymerase Chain Reaction', 'Red Meat', 'Signal Transduction', 'Stem Cell Niche', 'Stem Cells'] | 26,060,050 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['J01.040.246'], ['A10.336.482', 'A13.589'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['E05.393.620.500'], ['G07.203.300.600.813', 'J02.500.600.813'], ['G02.111.820', 'G04.835'], ['G04.366.249'], ['A11.872']] | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Multiple pre- and postreceptor defects in pseudohypoparathyroidism (a multicenter study with twenty four patients). | Three different pathophysiological mechanisms are probably responsible for hereditary pseudohypoparathyroidism: 1) a defect at the prereceptor-level, 2) a defective membrane N-protein accounting for diminished second messenger production, and 3) a defect in the cytosolic response to the hormone. In a cooperative, study... | ['Adolescent', 'Adult', 'Alkaline Phosphatase', 'Calcium', 'Child', 'Child, Preschool', 'Cyclic AMP', 'Female', 'GTP-Binding Proteins', 'Humans', 'Male', 'Parathyroid Hormone', 'Phosphates', 'Prolactin', 'Pseudohypoparathyroidism', 'Receptors, Cell Surface', 'Receptors, Parathyroid Hormone', 'Vitamin D'] | 3,001,127 | [['M01.060.057'], ['M01.060.116'], ['D08.811.277.352.650.035'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['M01.060.406'], ['M01.060.406.448'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['B01.050.150.900... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A novel hypothesis concerning the mechanisms of activation, and of control, of periodontal bone loss. | Chronic inflammatory periodontitis fulfills the classical definition of an infectious disease in that it is a disease of the host caused by the activities of one or more parasites. Typically, the etiology of an infectious disease has been defined as the specific microbe which incites the disease process, even though th... | ['Alveolar Bone Loss', 'Dinoprostone', 'Humans', 'Lipopolysaccharides', 'Models, Biological', 'Neutrophils', 'Periodontitis'] | 1,890,968 | [['C05.116.264.150', 'C07.465.714.354.500'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['E05.599.395'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Southern states receive insufficient ADAP money. North Carolina, Alabama face crises. | While the HIV epidemic has shifted toward poor, rural southern areas, the funding mechanism behind the AIDS Drug Assistance Program favors states with large urban areas where the epidemic first erupted decades ago, Southern AIDS advocates say. Even in states where legislatures contribute a large portion of the ADAP bud... | ['Alabama', 'Anti-HIV Agents', 'Budgets', 'Eligibility Determination', 'HIV Infections', 'Humans', 'Medical Assistance', 'North Carolina', 'Patient Advocacy', 'Waiting Lists'] | 15,300,945 | [['Z01.107.567.875.075.100', 'Z01.107.567.875.750.100'], ['D27.505.954.122.388.077.088'], ['N03.219.463.060'], ['N04.452.264'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.346.5... | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Psychological and family functioning and quality of life in adolescents with cystic fibrosis. | BACKGROUND: The life expectancy of individuals with CF has increased to 33 years. Thus, issues such as quality of life and psychological well-being, previously thought to be of lesser importance than physical well-being, are now recognised as significant factors. This study examined the interrelationships between quali... | ['Adolescent', 'Cystic Fibrosis', 'Family', 'Humans', 'Quality of Life', 'Social Support'] | 15,914,095 | [['M01.060.057'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['I01.880.853.500.600']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Postnatal Hyperplasic Effects of ActRIIB Blockade in a Severely Dystrophic Muscle. | The efficacy of two ActRIIB ligand-trapping agents (RAP-031 and RAP-435) in treating muscular dystrophy was examined by determining their morphological effects on the severely dystrophic triangularis sterni (TS) muscle of the mdx mouse, a model for Duchenne muscular dystrophy. These agents trap all endogenous ligands t... | ['Activin Receptors, Type II', 'Animals', 'Animals, Newborn', 'Body Weight', 'Cell Nucleus', 'Hyperplasia', 'Ligands', 'Mice, Inbred mdx', 'Muscle Fibers, Skeletal', 'Muscle, Skeletal', 'Muscular Dystrophy, Animal'] | 27,859,236 | [['D08.811.913.696.620.682.700.062.750', 'D12.776.543.750.750.400.820.500.750'], ['B01.050'], ['B01.050.050.282'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['C23.550.444'], ['D27.720.470.480']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Navigating virginities: enactment of sexual agency among Arab women in the USA. | People interpret virginity in a variety of ways with different implications for sexual identity and behaviour. In Arab societies, heterosexuality and compulsory virginity before marriage are traditionally understood as ideals for a 'good' Arab girl, a 'good' Arab family and, consequently, a 'good' Arab society. In this... | ['Adult', 'Arabs', 'Culture', 'Female', 'Humans', 'Interpersonal Relations', 'Interviews as Topic', 'Lebanon', 'Marriage', 'Pennsylvania', 'Qualitative Research', 'Sexual Abstinence', 'Sexual Behavior', 'Sexuality', 'Syria'] | 30,646,837 | [['M01.060.116'], ['M01.686.754.167'], ['I01.076.201.450', 'I01.880.853.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['Z01.252.245.500.450'], ['F01.829.263.315.500.500', 'I01.240.361.500.500', 'I01.880.853.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Phenomena ... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Rethinking Chronic Obstructive Pulmonary Disease. Chronic Pulmonary Insufficiency and Combined Cardiopulmonary Insufficiency. | Almost 70 years ago, Drs. Baldwin, Cournand, and Richards defined chronic pulmonary insufficiency by the presence of respiratory symptoms, radiologic evidence of pulmonary emphysema on chest radiography, and physiologic gas trapping. A decade later, airflow obstruction on spirometry was added to the definition and insu... | ['Forced Expiratory Volume', 'Humans', 'Lung', 'Pulmonary Disease, Chronic Obstructive', 'Pulmonary Emphysema', 'Pulmonary Heart Disease', 'Smoking', 'Spirometry', 'Tomography, X-Ray Computed', 'Ventricular Function, Right'] | 29,461,894 | [['E01.370.386.700.660.230', 'G09.772.650.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['C08.381.495.389'], ['C08.381.495.389.750'], ['C14.280.832'], ['F01.145.805'], ['E01.370.386.700.750'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Q-ACP: a questionnaire for evaluating visual and gestural complaints in patients with posterior cortical atrophy]. | INTRODUCTION: Posterior cortical atrophy (PCA) is a clinical neurodegenerative syndrome associated with atrophy in parieto-occipital cortices, and characterized by prominent disorders of higher visual processing, affecting both dorsal and ventral streams.METHODS: We used a questionnaire (Q-ACP) specifically designed to... | ['Aged', 'Agraphia', 'Alzheimer Disease', 'Atrophy', 'Caregivers', 'Cerebral Cortex', 'Demography', 'Female', 'Functional Laterality', 'Gestures', 'Humans', 'Male', 'Middle Aged', 'Neurodegenerative Diseases', 'Neuropsychological Tests', 'Psychomotor Performance', 'Reading', 'Space Perception', 'Surveys and Questionnai... | 21,429,543 | [['M01.060.116.100'], ['C10.597.606.150.500.050', 'C23.888.592.604.150.500.050'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['C23.300.070'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['A08.186.211.200.885.287.500'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['F02.830.297.425', 'G11.561.225.42... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Separation of four flavonol glycosides from Solanum rostratum Dunal using aqueous two-phase flotation followed by preparative high-performance liquid chromatography. | Aqueous two-phase flotation followed by preparative high-performance liquid chromatography was used to separate four flavonol glycosides from Solanum rostratum Dunal. In the aqueous two-phase flotation section, the effects of sublation solvent, solution pH, (NH4 )2 SO4 concentration in aqueous solution, cosolvent, N2 f... | ['Chemistry Techniques, Analytical', 'Chromatography, High Pressure Liquid', 'Flavonols', 'Glycosides', 'Magnetic Resonance Spectroscopy', 'Solanum'] | 27,868,353 | [['E05.196'], ['E05.196.181.400.300'], ['D03.383.663.283.266.450.284', 'D03.633.100.150.266.450.284'], ['D09.408'], ['E05.196.867.519'], ['B01.650.940.800.575.912.250.908.500.725']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intrinsic membrane properties underlying spontaneous tonic firing in neostriatal cholinergic interneurons. | Neostriatal cholinergic interneurons produce spontaneous tonic firing in the absence of synaptic input. Perforated patch recording and whole-cell recording combined with calcium imaging were used in vitro to identify the intrinsic membrane properties underlying endogenous excitability. Spontaneous firing was driven by ... | ['Action Potentials', 'Animals', 'Apamin', 'Calcium', 'Calcium Channel Blockers', 'Cell Membrane', 'Female', 'In Vitro Techniques', 'Interneurons', 'Large-Conductance Calcium-Activated Potassium Channels', 'Male', 'Neostriatum', 'Patch-Clamp Techniques', 'Potassium Channel Blockers', 'Potassium Channels', 'Potassium Ch... | 11,069,957 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['D20.888.065.115.060', 'D23.946.833.065.115.060'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['A11.284.149'], ['E05.481'], ['A08.675.358', 'A11.671.358'], ['D12.776.1... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hexosamine-containing macromolecules in human colon carcinomas. | Normal, transitional, and carcinoma areas of five colons resected for carcinoma were examined morphologically, histochemically, and biochemically. The transitional area contained a larger amount of non-sulphated acid mucin than the normal mucosa as verified histochemically. Normal mucosa contained mainly sulphated muci... | ['Adenocarcinoma', 'Chondroitin Sulfates', 'Colonic Neoplasms', 'Dermatan Sulfate', 'Fucose', 'Galactosamine', 'Galactose', 'Glucosamine', 'Glycopeptides', 'Glycosaminoglycans', 'Heparitin Sulfate', 'Hexosamines', 'Histocytochemistry', 'Humans', 'Hyaluronic Acid', 'Intestinal Mucosa', 'Macromolecular Substances', 'Mole... | 834,971 | [['C04.557.470.200.025'], ['D09.698.373.200.300'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['D09.698.373.200.380'], ['D09.254.488'], ['D09.067.342.356'], ['D09.947.875.359.377'], ['D09.067.342.531'], ['D09.400.420', 'D1... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Mitochondrial shape and function in trypanosomes requires the outer membrane protein, TbLOK1. | In an RNAi library screen for loss of kinetoplast DNA (kDNA), we identified an uncharacterized Trypanosoma brucei protein, named TbLOK1, required for maintenance of mitochondrial shape and function. We found the TbLOK1 protein located in discrete patches in the mitochondrial outer membrane. Knock-down of TbLOK1 in proc... | ['DNA, Kinetoplast', 'Humans', 'Membrane Proteins', 'Mitochondria', 'Protozoan Proteins', 'Trypanosoma brucei brucei', 'Trypanosomiasis, African'] | 23,336,702 | [['D13.444.308.283.225.200', 'D13.444.308.442.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D12.776.820'], ['B01.268.475.868.887.080'], ['C01.610.752.300.900.719', 'C01.920.937']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distinct roles of RalA and RalB in the progression of cytokinesis are supported by distinct RalGEFs. | The Ras family G-proteins RalA and RalB make critical non-overlapping contributions to the generation of a tumorigenic regulatory network, supporting bypass of the normal restraints on both cell proliferation and survival. The Sec6/8 complex, or exocyst, has emerged as a principal direct effector complex for Ral GTPase... | ['Cell Nucleus', 'Cell Proliferation', 'Cell Survival', 'Cytokinesis', 'Gene Expression Regulation', 'HeLa Cells', 'Humans', 'Kinetics', 'Mitosis', 'Models, Biological', 'Vesicular Transport Proteins', 'ral GTP-Binding Proteins', 'ral Guanine Nucleotide Exchange Factor', 'ras Proteins'] | 18,756,269 | [['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['G04.144.220.250'], ['G05.308'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['G04.144.220.220.781', 'G05.113.220... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metadherin/Astrocyte elevated gene-1 positively regulates the stability and function of forkhead box M1 during tumorigenesis. | Background: Forkhead box M1 (FOXM1) is overexpressed and activates numerous oncoproteins in tumors. However, the mechanism by which the FOXM1 protein aberrantly accumulates in human cancer remains uncertain. This study was designed to clarify the upstream signaling pathway(s) that regulate FOXM1 protein stability and t... | ['Animals', 'Apoptosis', 'Astrocytes', 'Cadherins', 'Cell Adhesion Molecules', 'Cell Proliferation', 'Cell Transformation, Neoplastic', 'Forkhead Box Protein M1', 'Gene Expression Regulation, Neoplastic', 'Glioblastoma', 'Humans', 'Membrane Proteins', 'Mice', 'Protein Stability', 'RNA-Binding Proteins', 'Signal Transdu... | 27,923,917 | [['B01.050'], ['G04.146.954.035'], ['A08.637.200', 'A11.650.200'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.697.098.500', 'C23.550.727.098.500'], ['D12.776.260.950.249.0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of mineral water on metabolic processes]. | The paper comparatively analyzes the effect of the mineral water "Penta" on the biochemical parameters of blood and urine, which characterize the functional activity of renal metabolic processes. A group comprising 10 examinees without renal disease took water by the routine mineral water scheme for 4 days. Comparison ... | ['Azotemia', 'Female', 'Humans', 'Kidney Calculi', 'Male', 'Mineral Waters', 'Oxalates', 'Time Factors', 'Uric Acid'] | 16,925,059 | [['C12.777.419.936.231', 'C13.351.968.419.936.231', 'C23.550.145'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.600.500', 'C12.777.967.249.500', 'C12.777.967.500.503', 'C13.351.968.419.600.500', 'C13.351.968.967.249.500', 'C13.351.968.967.500.503', 'C23.300.175.850.550'], ['D01.045.250.875.600', 'D01... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Outcomes and predictors of T3a prostate cancer treated by permanent interstitial brachytherapy combined with external radiotherapy and hormone therapy]. | OBJECTIVE: To evaluate the outcomes of T3a prostate cancer treated by permanent interstitial brachytherapy combined with external radiotherapy and hormone therapy, and analyse the influence of preoperative factors on prognosis.METHODS: From January 2003 to December 2008, 38 pactients with T3a prostate cancer aged from ... | ['Aged', 'Aged, 80 and over', 'Brachytherapy', 'Combined Modality Therapy', 'Hormones', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Prognosis', 'Prostate-Specific Antigen', 'Prostatic Neoplasms', 'Radiotherapy', 'Survival Rate', 'Treatment Outcome'] | 25,573,217 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.815.150'], ['E02.186'], ['D06.472', 'D27.505.696.399.472'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['E01.789'], ['D08.811.277.656.300.760.442.750', 'D08.811.277.656.959.350.442.750', 'D12.776.866.249.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Morphologic analysis of normal human lumbar dorsal root ganglion by 3D MR imaging. | BACKGROUND AND PURPOSE: The dorsal root ganglion (DRG) of the spinal nerve has been considered a key structure in the mechanism of low-back pain and radicular symptoms. The purpose of this study was to clarify the normal morphologic features and variations of the lumbar DRGs in a healthy population by using 3D MR imagi... | ['Adolescent', 'Adult', 'Aged', 'Female', 'Ganglia, Spinal', 'Humans', 'Imaging, Three-Dimensional', 'Lumbosacral Region', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Reference Values'] | 17,110,675 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['A01.923.176.519'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E05.978.810']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Modification of interpretive breakpoints for netilmicin disk susceptibility tests with Pseudomonas aeruginosa. | Regression analysis of data correlating 30-micrograms netilmicin disk zone diameters with microdilution MICs, obtained by testing close-interval dilution steps, was performed with 77 selected strains of Pseudomonas aeruginosa, each tested in three independent laboratories. A zone of greater than or equal to 15 mm corre... | ['Drug Resistance, Microbial', 'Gentamicins', 'Microbial Sensitivity Tests', 'Netilmicin', 'Pseudomonas aeruginosa'] | 6,425,354 | [['G06.225', 'G07.690.773.984.269'], ['D09.408.051.374'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D09.408.051.374.785.525'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Real-time estimation of FLE statistics for 3-D tracking with point-based registration. | Target registration error (TRE) has become a widely accepted error metric in point-based registration since the error metric was introduced in the 1990s. It is particularly prominent in image-guided surgery (IGS) applications where point-based registration is used in both image registration and optical tracking. In poi... | ['Algorithms', 'Anisotropy', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Models, Theoretical', 'Monte Carlo Method', 'Reproducibility of Results'] | 19,336,301 | [['G17.035', 'L01.224.050'], ['G01.590.040', 'G02.050'], ['L01.224.308'], ['E01.370.350.400', 'L01.224.308.410'], ['E05.599'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Preliminary study of the clinical value of colposcopy in diagnosing vagina invasion in cervical cancer]. | Objective: To explore the preliminary clinical values of colposcopy in the diagnosis of vaginal invasion in cervical cancer. Methods: A retrospective review of the clinical records of patients (31 cases) with cervical cancer treated in Xuzhou Cancer Hospital from April 2015 to August 2019. For those with early-stage ce... | ['Biopsy', 'Colposcopy', 'Female', 'Humans', 'Pregnancy', 'Retrospective Studies', 'Uterine Cervical Neoplasms', 'Vagina', 'Vaginal Neoplasms', 'Vaginal Smears'] | 32,464,720 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.370.378.150', 'E01.370.388.250.150', 'E04.502.250.150', 'E04.520.150', 'E04.950.300.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['E05.318... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Determination of advanced glycation end-products on IgG in liver cirrhosis. | BACKGROUND/AIMS: Our previous report showed that IgG levels are strongly correlated with the indocyanine green (ICG) retention rate in patients with liver cirrhosis (LC). This correlation suggests that hyperglobulinemia in LC could be explained by impairment of hepatic removal function. To estimate IgG turnover in LC, ... | ['Aged', 'Arthritis, Rheumatoid', 'Female', 'Glycation End Products, Advanced', 'Humans', 'Immunoglobulin G', 'Liver Cirrhosis', 'Lupus Erythematosus, Systemic', 'Lysine', 'Male', 'Middle Aged'] | 20,214,227 | [['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D12.776.643.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['C06.552.630', 'C23.550.355.412'], ['C17.300.480',... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of cyclosporin A and some derivatives in Litomosoides carinii-infected Mastomys natalensis. | Litomosoides carinii-infected Mastomys natalensis were treated 85 days post infection with cyclosporin A (CyA) or 8 derivatives with different immunosuppressive capacities. CyA (oral doses of 5 X 25 mg/kg, 5 X 50 mg/kg, 5 X 80 mg/kg on consecutive days) reduced parasitaemia levels in a dose dependent way, beginning 3 w... | ['Animals', 'Cyclosporins', 'Filariasis', 'Filarioidea', 'Immunosuppression', 'Microfilariae', 'Muridae'] | 3,437,108 | [['B01.050'], ['D04.345.566.235', 'D12.644.641.235'], ['C01.610.335.508.700.750.361'], ['B01.050.500.500.294.400.937.463'], ['E02.095.465.425.450', 'E05.478.610'], ['B01.050.500.500.294.400.937.463.470', 'B05.525'], ['B01.050.150.900.649.313.992.635']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Surface induced collapse of Aâ1-42 with the F19A replacement following adsorption on a single walled carbon nanotube. | Spontaneous adsorption of the Aâ peptide on the surface of a single-walled carbon nanotube, resulting in the prevention of its intrinsic propensity to form collapsed states, could be a plausible means to hinder the peptide's initial nucleation and self-assembly. We report here the effects of sharply reducing both aroma... | ['Adsorption', 'Amyloid beta-Peptides', 'Mutation', 'Nanotubes, Carbon', 'Peptide Fragments', 'Surface Properties', 'Thermodynamics'] | 24,231,630 | [['G01.030', 'G02.020'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['G05.365.590'], ['D01.268.150.250.500', 'J01.637.512.850.500'], ['D12.644.541'], ['G02.860'], ['G01.906']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Dendrimeric coating of glass slides for sensitive DNA microarrays analysis. | Successful use and reliability of microarray technology is highly dependent on several factors, including surface chemistry parameters and accessibility of cDNA targets to the DNA probes fixed onto the surface. Here, we show that functionalisation of glass slides with homemade dendrimers allow production of more sensit... | ['DNA, Complementary', 'Oligonucleotide Array Sequence Analysis', 'Oligonucleotide Probes', 'Phosphorus', 'Polymers', 'Polymorphism, Single Nucleotide', 'Propylamines', 'Sensitivity and Specificity', 'Silanes', 'Surface Properties'] | 12,907,740 | [['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['D13.444.600.601', 'D27.505.259.750.600.650', 'D27.720.470.530.600.650'], ['D01.268.666'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['G05.365.795.598'], ['D02.092.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Comparison of intubating conditions after rocuronium or vecuronium when the timing of intubation is judged by clinical criteria. | The onset of action and intubating conditions after rocuronium 0.6 mg kg-1 or vecuronium 0.1 mg kg-1 were compared in a randomized, double-blind study when the timing of tracheal intubation was determined by clinical judgment alone. Times to laryngoscopy and completion of intubation were mean 89 (SD 20) s and 119 (28) ... | ['Adult', 'Androstanols', 'Double-Blind Method', 'Humans', 'Intubation, Intratracheal', 'Laryngoscopy', 'Neuromuscular Blockade', 'Neuromuscular Nondepolarizing Agents', 'Rocuronium', 'Time Factors', 'Vecuronium Bromide'] | 9,602,591 | [['M01.060.116'], ['D04.210.500.054.040'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['E01.370.386.460', 'E01.370.388.250.525', 'E04.502.250.525', 'E04.580.373'], ['E03.706', 'E05.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
bFGF promotes the survival of entorhinal layer II neurons after perforant path axotomy. | Infusion of basic fibroblast growth factor (bFGF) prevents the loss of cholinergic neurons in the septum/diagonal band of broca following fimbria-fornix transection. However, an in vivo test of whether bFGF will also rescue injured non-cholinergic or cortical neurons has not been carried out. Previous studies have show... | ['Animals', 'Axons', 'Cell Survival', 'Fibroblast Growth Factor 2', 'Hippocampus', 'Male', 'Neural Pathways', 'Neurons', 'Rats', 'Rats, Sprague-Dawley'] | 1,446,240 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['G04.346'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['A08.612'], ['A08.675', 'A11.671'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid identification of cervus | A rapid PCR technology was developed to differentiate Cervus antlers species and adulteration based on the difference in mitochondrial genome. Three specifically designed primer sets were confirmed to have high inter-species specificity and good intra-species stability. Limits of detection were estimated to be 1 ng of ... | ['Animals', 'Antlers', 'DNA Primers', 'Deer', 'Drug Contamination', 'Genome, Mitochondrial', 'Medicine, Chinese Traditional', 'Polymerase Chain Reaction', 'Time Factors'] | 30,663,383 | [['B01.050'], ['A13.507.288'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['B01.050.150.900.649.313.500.380.373'], ['N06.850.360'], ['G05.360.340.360'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['E05.393.620.500'], ['G01.910.857']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Radiotherapy-induced Cherenkov luminescence imaging in a human body phantom. | Radiation therapy produces Cherenkov optical emission in tissue, and this light can be utilized to activate molecular probes. The feasibility of sensing luminescence from a tissue molecular oxygen sensor from within a human body phantom was examined using the geometry of the axillary lymph node region. Detection of reg... | ['Humans', 'Image Processing, Computer-Assisted', 'Optical Imaging', 'Phantoms, Imaging', 'Radiotherapy', 'Signal-To-Noise Ratio'] | 29,560,623 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.589', 'E05.642'], ['E07.671'], ['E02.815'], ['E05.318.370.800.875', 'E05.318.740.872.875', 'G17.800.500', 'N05.715.360.325.700.840', 'N05.715.360.750.725.750', 'N06.850.520.445.800.875', 'N06.850.520.830.872.750']] | ['Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
TM2D3 rs675436 or FGFR2 rs755793 polymorphisms and susceptibility to Epstein-Barr virus-associated tumors in Chinese Han population. | Epstein-Barr virus (EBV) is etiologically linked to nasopharyngeal carcinoma, lymphoma, and gastric carcinoma. The aim of this study was to assess the association of TM2 domain containing 3 (TM2D3) and fibroblast growth factor receptor 2 (FGFR2) SNPs rs675436 and rs755793 with susceptibility to EBV-associated tumors in... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Asian Continental Ancestry Group', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Epstein-Barr Virus Infections', 'Female', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Humans', 'Lymphoma', 'Male', 'Middle Aged', 'Nasopharyngeal Carcin... | 29,446,487 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.686.508.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['C01.925.256.466.313', 'C01.925.928.313'], ['E05.393.385'], ['C23.550.291.687.500', 'G05.380.355'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Symmetric corticobasal degeneration (S-CBD). | BACKGROUND: Corticobasal degeneration (CBD) is a neurodegenerative disease characterized pathologically by neuronal loss, gliosis and tau deposition in neocortex, basal ganglia and brainstem. Typical clinical presentation is known as corticobasal syndrome (CBS) and involves the core features of progressive asymmetric r... | ['Aged', 'Aged, 80 and over', 'Basal Ganglia', 'Cerebral Cortex', 'Disease Progression', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neurodegenerative Diseases', 'Neuropsychological Tests', 'Radiography', 'Retrospective Studies'] | 20,018,548 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A08.186.211.200.885.287.249'], ['A08.186.211.200.885.287.500'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C10.574'], ['F04.711.513'], ['E01.370.350.700'], ['E05.318.372.500.500.500', 'E05.318.372... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Histone deacetylase 2 in the mouse hippocampus: attenuation of age-related increase by caloric restriction. | The aging process in the hippocampus is associated with aberrant epigenetic marks, such as DNA methylation and histone tail alterations. Recent evidence suggests that caloric restriction (CR) can potentially delay the aging process, while upregulation of antioxidants may also have a beneficial effect in this respect. W... | ['Aging', 'Animals', 'Caloric Restriction', 'Hippocampus', 'Histone Deacetylase 2', 'Male', 'Mice'] | 24,093,534 | [['G07.345.124'], ['B01.050'], ['E02.642.249.200', 'G07.203.650.240.340.150'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D08.811.277.087.520.500.200', 'D08.811.277.087.520.750.200', 'D08.811.600.620.200', 'D08.811.600.795.200'], ['B01.050.150.900.649.313.992.635.505.500']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A multivariate model of patients' satisfaction with treatment for posttraumatic stress disorder. | Prior studies have concluded that patients' pretreatment characteristics contribute more to their satisfaction with mental health treatment than any other domain. We expand the representation of treatment characteristics in an examination of satisfaction across both inpatient and outpatient settings. Data were drawn fr... | ['Adult', 'Humans', 'Inpatients', 'Male', 'Middle Aged', 'Models, Psychological', 'Multivariate Analysis', 'Outpatients', 'Patient Satisfaction', 'Prognosis', 'Social Support', 'Stress Disorders, Post-Traumatic', 'Treatment Outcome', 'Veterans'] | 12,602,657 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['M01.060.116.630'], ['E05.599.695'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['M01.643.630'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Total synthesis of the biscarbazole alkaloids murrafoline A-D by a domino sonogashira coupling/claisen rearrangement/electrocyclization reaction. | Why take things one step at a time? Aryl-pyran-linked biscarbazole alkaloids of the murrafoline group (see crystal structure of murrafoline A; dark gray: C, red: O, blue: N) were accessed readily by a novel domino reaction sequence involving Sonogashira coupling, a Claisen rearrangement, and electrocyclization. The one... | ['Alkaloids', 'Carbazoles', 'Catalysis', 'Crystallography, X-Ray', 'Cyclization', 'Molecular Structure', 'Stereoisomerism'] | 24,006,179 | [['D03.132'], ['D03.633.100.473.144', 'D03.633.300.148'], ['G02.130'], ['E05.196.309.742.225'], ['G02.111.180', 'G02.607.133', 'G03.208'], ['G02.111.570', 'G02.466'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Upregulation of HIV-1 replication in chronically infected cells by ingenol derivatives. | We have previously reported that ingenol derivatives are highly potent inhibitors of human immunodeficiency virus type 1 (HIV-1) replication in acutely infected cells. In this study, however, we have found that some ingenol derivatives strongly enhance the replication of HIV-1 in chronically infected cells at nanomolar... | ['Butyrates', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Diterpenes', 'HIV Core Protein p24', 'HIV-1', 'Humans', 'NF-kappa B', 'Protein Kinase C', 'Up-Regulation', 'Virus Replication'] | 9,856,087 | [['D02.241.081.114', 'D10.251.400.143'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['D02.455.849.291'], ['D12.776.964.775.350.362.500', 'D12.776.964.775.562.750.500', 'D12.776.964.970.600.850.350.362.500', 'D23.050.327.520.300'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.31... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevention of re-fractures of both bones of the forearm in children. | PURPOSE: The aim of this study was to observe if the re-fracture rate after forearm both bones was decreased by protecting the forearm with a preventive brace for 6 months following the fracture and by ceasing all physical activities.METHODS: We performed a retrospective study in 75 consecutive cases of diaphyseal frac... | ['Braces', 'Casts, Surgical', 'Child', 'Child, Preschool', 'Closed Fracture Reduction', 'Diaphyses', 'Female', 'Forearm Injuries', 'Humans', 'Immobilization', 'Infant', 'Male', 'Radius Fractures', 'Recurrence', 'Retrospective Studies', 'Return to Sport', 'Secondary Prevention', 'Ulna Fractures'] | 29,182,132 | [['E07.858.442.743.319'], ['E07.858.442.660.430.500', 'E07.858.690.725.430.500'], ['M01.060.406'], ['M01.060.406.448'], ['E04.555.300.150'], ['A02.835.232.169'], ['C26.088.268'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.472'], ['M01.060.703'], ['C26.088.268.556', 'C26.404.562'], ['C23.550.291.937'], ['E05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[The Rapeutic principles in malignant rectal polyps based on late results]. | The late results of various treatment of 114 patients with malignant rectal polyps were found to be similar over a 5-25-year follow-up. On this basis, the following principles of therapy were established: 1. All rectal polyps should be removed completely. 2. Local removal of a malignant polyp, looking macroscopically b... | ['Humans', 'Intestinal Polyps', 'Methods', 'Neoplasm Recurrence, Local', 'Postoperative Complications', 'Rectal Neoplasms', 'Time Factors'] | 837,781 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.825.411'], ['E05.581'], ['C04.697.655', 'C23.550.727.655'], ['C23.550.767'], ['C04.588.274.476.411.307.790', 'C06.301.371.411.307.790', 'C06.405.249.411.307.790', 'C06.405.469.491.307.790', 'C06.405.469.860.180.500'], ['G01.910.857']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A quality by design approach for longitudinal quality attributes. | The concept of quality by design (QbD) as published in ICH-Q8 is currently one of the most recurrent topics in the pharmaceutical literature. This guideline recommends the use of information and prior knowledge gathered during pharmaceutical development studies to provide a scientific rationale for the manufacturing pr... | ['Bayes Theorem', 'Biopharmaceutics', 'Chemistry, Pharmaceutical', 'Data Interpretation, Statistical', 'Delayed-Action Preparations', 'Guidelines as Topic', 'Kinetics', 'Models, Statistical', 'Quality Control', 'Solubility', 'Tablets', 'Technology, Pharmaceutical', 'Time Factors'] | 25,360,720 | [['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['H01.158.703.003', 'H02.628.049'], ['H01.158.703.007', 'H01.181.466'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['D26.255.210', 'E02.319.300.253'], ['N04.761.700.350', 'N0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Effect of hemin on the physiology and virulence of Bacteroides gingivalis W50. | Bacteroides gingivalis W50 was grown in a chemostat under steady-state conditions at pH 7.5 +/- 0.2 and a constant growth rate of 6.9 h for periods of up to 6 weeks (146 bacterial generations) in a complex medium. Hemin was capable of limiting the growth of cells up to a concentration of approximately 0.5 micrograms/ml... | ['Animals', 'Bacteroides', 'Culture Media', 'Fatty Acids', 'Heme', 'Hemin', 'Mice', 'Skin Diseases'] | 3,699,884 | [['B01.050'], ['B03.440.080.094.152', 'B03.440.425.410.194.152'], ['D27.720.470.305', 'E07.206'], ['D10.251'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['D03.383.129.578.840.500.640.587.462', 'D03.633.400.909.500.640.587.462', 'D04.345.783.500... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Advanced practice in pediatric nursing: blending roles. | In the past, pediatric advanced practice nurse's roles were the Clinical Nurse Specialist (CNS) in the inpatient setting and the Nurse Practitioner (NP) in the outpatient setting. With health care system changes, such as the shifting and blurring boundaries between inpatient and outpatient care, changes were required i... | ['Ambulatory Care', 'Chicago', 'Clinical Competence', 'Curriculum', 'Education, Nursing, Graduate', 'Evidence-Based Medicine', 'Hospitalization', 'Humans', 'Intensive Care, Neonatal', 'Job Description', 'Models, Educational', 'Models, Nursing', 'Needs Assessment', 'Nurse Clinicians', 'Nurse Practitioners', 'Nursing Edu... | 11,326,400 | [['E02.760.106', 'N02.421.585.106'], ['Z01.107.567.875.350.350.200', 'Z01.107.567.875.510.350.200', 'Z01.433.305'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.158'], ['I02.358.337.450', 'I02.358.462.565'], ['H02.249.750', 'H02.403.200.400'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.98... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Information needs and experiences: an audit of UK cancer patients. | As part of a multi-centred UK study evaluating multidisciplinary team communication, the information needs, decision making preferences and information experiences of 394 cancer patients were audited. A majority of patients (342/394, 87%) wanted all possible information, both good and bad news. Assuming that all clinic... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Attitude to Health', 'Communication', 'Decision Making', 'Female', 'Humans', 'Male', 'Middle Aged', 'Needs Assessment', 'Neoplasms', 'Nursing Audit', 'Nursing Methodology Research', 'Patient Care Team', 'Patient Education as Topic', "Physician's Role", 'Power, Psyc... | 16,376,146 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.100.150', 'N05.300.150'], ['F01.145.209', 'L01.143'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I02.594', 'N03.349.380.565', 'N05.300.537'], ['C04'], ['N04.761... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
The mutational specificity of simulated sunlight at the aprt locus in rodent cells. | To elucidate the nature of sunlight mutagenesis in mammalian cells, the mutational specificity of simulated solar light (SSL) has been established at the Chinese hamster ovary adenine phosphoribosyltransferase (aprt) locus. Among a collection of 36 independent SSL-induced mutations, the majority were single or tandem d... | ['Adenine Phosphoribosyltransferase', 'Animals', 'Base Sequence', 'CHO Cells', 'Chromosome Mapping', 'Cricetinae', 'Genes, p53', 'Molecular Sequence Data', 'Mutation', 'Sunlight', 'Ultraviolet Rays'] | 8,055,636 | [['D08.811.913.400.725.100'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.200', 'A11.436.155'], ['E05.393.183'], ['B01.050.150.900.649.313.992.635.075.250'], ['G05.360.340.024.340.375.249.385', 'G05.360.340.024.340.415.400.385'], ['L01.453.245.667'], ['G05.365.590'], ['G01.358.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Chemokine receptor CCR-5 inhibitors produced by Chaetomium globosum. | Two novel chemokine receptor CCR-5 inhibitors, Sch 210971 (1) and Sch 210972 (2), were isolated from the fungal fermentation broth of Chaetomium globosum by normal- and reversed-phase HPLC purifications. The structure determination of 1 and 2 was accomplished on the basis of UV, MS, and NMR spectral data analyses inclu... | ['Anti-HIV Agents', 'Arizona', 'CCR5 Receptor Antagonists', 'Chaetomium', 'Crystallography, X-Ray', 'Heterocyclic Compounds, 4 or More Rings', 'Humans', 'Inhibitory Concentration 50', 'Molecular Structure', 'Plant Leaves', 'Spectrometry, Mass, Electrospray Ionization'] | 16,872,138 | [['D27.505.954.122.388.077.088'], ['Z01.107.567.875.760.100'], ['D27.505.519.275', 'D27.505.954.122.388.077.088.104'], ['B01.300.107.800.150'], ['E05.196.309.742.225'], ['D03.633.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.940.350', 'G07.690.936.563'], ['G02.111.570', 'G02.466'], ['A18.024.812'], ['E0... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Joint attention and symbolic play in young children with autism: a randomized controlled intervention study. | BACKGROUND: Delays and deficits in joint attention and symbolic play constitute two important developmental problems in young children with autism. These areas of deficit have been well studied in autism but have rarely been the focus of treatment efforts (see Kasari, Freeman, & Paparella, 2001). In this study, we exam... | ['Adult', 'Attention', 'Autistic Disorder', 'Caregivers', 'Child', 'Child, Preschool', 'Communication', 'Female', 'Humans', 'Interpersonal Relations', 'Male', 'Play and Playthings', 'Social Behavior', 'Symbolism'] | 16,712,638 | [['M01.060.116'], ['F02.830.104.214'], ['F03.625.164.113.500'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['M01.060.406'], ['M01.060.406.448'], ['F01.145.209', 'L01.143'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['I03.450.642.693'], ['F01.145.813'], ['K01.400.899', 'K01.752.798']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
p53 activates the PANK1/miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins. | The tumor suppressor p53 is a central regulator of cell-cycle arrest and apoptosis by acting as a transcription factor to regulate numerous genes. We identified all human p53-regulated mRNAs by microarray analyses and searched for protein-coding genes which contain intronic miRNAs. Among others, this analysis yielded t... | ['Cell Cycle', 'Cell Cycle Proteins', 'Cell Line', 'Computational Biology', 'Cyclin-Dependent Kinase 6', 'DNA Damage', 'Down-Regulation', 'Gene Expression Regulation', 'Genetic Loci', 'Humans', 'Introns', 'MicroRNAs', 'Phosphotransferases (Alcohol Group Acceptor)', 'Promoter Regions, Genetic', 'Protein Biosynthesis', '... | 20,833,636 | [['G04.144'], ['D12.776.167'], ['A11.251.210'], ['H01.158.273.180', 'L01.313.124'], ['D08.811.913.696.620.682.700.646.500.937', 'D12.644.360.250.515', 'D12.776.167.200.515', 'D12.776.476.250.515'], ['G05.200'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G05.308'], ['G05.360.340.024.380'], ['B01.050.150.900.64... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Characterisation of tissue shrinkage during microwave thermal ablation. | PURPOSE: The aim of this study was to characterise changes in tissue volume during image-guided microwave ablation in order to arrive at a more precise determination of the true ablation zone.MATERIALS AND METHODS: The effect of power (20-80 W) and time (1-10 min) on microwave-induced tissue contraction was experimenta... | ['Animals', 'Cattle', 'Liver', 'Microwaves', 'Muscles', 'Phantoms, Imaging', 'Turkeys'] | 25,323,026 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A03.620'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['A02.633', 'A10.690'], ['E07.671'], ['B01.050.150.900.248.350.800', 'B01.050.150.900.248.690.800']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Screening of stress enhancer based on analysis of gene expression profiles: enhancement of hyperthermia-induced tumor necrosis by an MMP-3 inhibitor. | To improve the therapeutic benefit of hyperthermia, we examined changes of global gene expression after heat shock using DNA microarrays consisting of 12 814 clones. HeLa cells were treated for 1 h at 44 degrees C and RNA was extracted from the cells 0, 3, 6, and 12 h after heat shock. The 664 genes that were up or dow... | ['Cell Survival', 'DNA-Binding Proteins', 'Early Growth Response Protein 1', 'Gene Expression Regulation, Neoplastic', 'Genes, fos', 'Genes, jun', 'HeLa Cells', 'Hot Temperature', 'Humans', 'Immediate-Early Proteins', 'Kinetics', 'Matrix Metalloproteinase Inhibitors', 'Multigene Family', 'Oligonucleotide Array Sequence... | 12,841,876 | [['G04.346'], ['D12.776.260'], ['D12.776.260.158.500', 'D12.776.460.525.500', 'D12.776.930.213.500'], ['G05.308.370'], ['G05.360.340.024.340.375.500.791.330'], ['G05.360.340.024.340.375.500.791.365'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Anti-Mycobacterium avium activity of quinolones: in vitro activities. | The MICs of 88 quinolones against 14 selected reference and clinical strains of Mycobacterium avium-M. intracellular complex were determined. Agents tested included ciprofloxacin, sparfloxacin (PD 131501), and 86 other experimental quinolones. Test strains were selected to represent various susceptibilities to ciproflo... | ['Anti-Infective Agents', 'Ciprofloxacin', 'Drug Resistance, Microbial', 'Humans', 'Microbial Sensitivity Tests', 'Mycobacterium avium Complex'] | 8,239,587 | [['D27.505.954.122'], ['D03.633.100.810.835.322.186'], ['G06.225', 'G07.690.773.984.269'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['B03.510.024.962.500.720.100', 'B03.510.460.400.410.552.552.720.100']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gingival recession treatment with connective tissue grafts in smokers and non-smokers. | BACKGROUND: Cigarette smoking can adversely affect the results of many periodontal procedures. The purpose of this study was to determine whether cigarette smoking affects wound healing of subepithelial connective tissue grafts.METHODS: Seventeen systemically healthy patients with 22 Miller Class I or II mucogingival d... | ['Adult', 'Connective Tissue', 'Cotinine', 'Female', 'Gingiva', 'Gingival Recession', 'Gingivoplasty', 'Humans', 'Male', 'Middle Aged', 'Periodontal Index', 'Prospective Studies', 'Saliva', 'Smoking', 'Wound Healing'] | 16,805,676 | [['M01.060.116'], ['A10.165'], ['D03.383.773.812.180'], ['A14.549.167.646.480'], ['C07.465.714.258.447', 'C07.465.714.354.625'], ['E04.545.355', 'E06.645.355', 'E06.721.384'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.980.438.300.725', 'E06.208.720', 'E06.721.658', 'N05.715.360... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dual delivery of BMP-2 and bFGF from a new nano-composite scaffold, loaded with vascular stents for large-size mandibular defect regeneration. | The aim of this study was to investigate the feasibility and advantages of the dual delivery of bone morphogenetic protein-2 (BMP-2) and basic fibroblast growth factor (bFGF) from nano-composite scaffolds (PLGA/PCL/nHA) loaded with vascular stents (PLCL/Col/nHA) for large bone defect regeneration in rabbit mandibles. T... | ['Alginates', 'Alkaline Phosphatase', 'Animals', 'Biocompatible Materials', 'Blood Vessel Prosthesis', 'Bone Density', 'Bone Morphogenetic Protein 2', 'Bone Regeneration', 'Cattle', 'Cell Proliferation', 'Drug Delivery Systems', 'Fibroblast Growth Factor 2', 'Glucuronic Acid', 'Hexuronic Acids', 'Hydrogel, Polyethylene... | 23,778,088 | [['D09.698.068'], ['D08.811.277.352.650.035'], ['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['E07.695.110'], ['G11.427.100'], ['D12.644.276.954.200.200', 'D12.776.467.942.200.200', 'D23.529.942.200.200'], ['G11.427.213.140', 'G16.762.150.150'], ['B01.050.150.900.649.313.500.380.271'], ['G04.161.750',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
THE EFFECT OF SEROTONIN 5-HT1A, 5-HT2 RECEPTOR LIGANDS, KETOPROFEN AND THEIR COMBINATION IN MODELS OF INDUCED PAIN IN MICE. | The present study was carried out to investigate the effects of the 7-(3-chlorophenyl)piperazinylalkyl derivatives of 8-alkoxypurine-2,6-dione (compounds 1-4) in two animal models of induced pain and to compare their effects with ketoprofen and with their combination. All experiments were performed on albino mice. Mice... | ['Analgesics', 'Animals', 'Disease Models, Animal', 'Drug Therapy, Combination', 'Ketoprofen', 'Male', 'Mice', 'Pain', 'Receptor, Serotonin, 5-HT1A', 'Receptors, Serotonin, 5-HT2'] | 26,642,666 | [['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.319.310'], ['D02.241.223.701.480'], ['B01.050.150.900.649.313.992.635.505.500'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['D12.776.543.750.670.800.100.100', 'D12.776.543.750.695.800.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gastric lipase secretion in children with gastritis. | Gastric lipase is one of the prepancreatic lipases found in some mammalian species and in humans. Our knowledge of the hormonal regulation of gastric lipase secretion in children and adolescents is still very limited. The aim of this study was to compare the activity of human gastric lipase (HGL) in gastric juice in he... | ['Adolescent', 'Body Mass Index', 'Body Weight', 'Case-Control Studies', 'Cholecystokinin', 'Fasting', 'Gastric Inhibitory Polypeptide', 'Gastritis', 'Gastrointestinal Tract', 'Glucagon-Like Peptide 1', 'Helicobacter Infections', 'Humans', 'Hydrogen-Ion Concentration', 'Lipase', 'Young Adult'] | 23,899,880 | [['M01.060.057'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D06.472.31... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The postman always rings twice: two cases of shotgun deaths associated with an unconventional home security alarm system. | Injury and death cases caused by booby traps are not common in forensic medicine practice. Besides, installation of booby traps including firearms is generally for suicidal and rarely for homicidal purposes. Although few patents were described about home security alarm system that were created by firearms in the United... | ['Accidents, Home', 'Aged', 'Female', 'Forensic Medicine', 'Humans', 'Male', 'Photography', 'Security Measures', 'Wounds, Gunshot'] | 24,781,392 | [['N06.850.135.217'], ['M01.060.116.100'], ['H02.403.330', 'I01.198.780.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600', 'E05.712'], ['N04.452.910'], ['C26.986.900']] | ['Health Care [N]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Point-of-care, smartphone-based, dual-modality, dual-view, oral cancer screening device with neural network classification for low-resource communities. | Oral cancer is a growing health issue in a number of low- and middle-income countries (LMIC), particularly in South and Southeast Asia. The described dual-modality, dual-view, point-of-care oral cancer screening device, developed for high-risk populations in remote regions with limited infrastructure, implements autofl... | ['Cloud Computing', 'Early Detection of Cancer', 'Humans', 'Mobile Applications', 'Mouth Neoplasms', 'Neural Networks, Computer', 'Optical Imaging', 'Point-of-Care Systems', 'Poverty', 'Sensitivity and Specificity', 'Smartphone'] | 30,517,120 | [['L01.224.097'], ['E01.390.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.900.685'], ['C04.588.443.591', 'C07.465.530'], ['G17.485', 'L01.224.050.375.605'], ['E01.370.350.589', 'E05.642'], ['N04.452.442.452.452.680', 'N04.452.515.360.652', 'N04.590.874'], ['I01.880.735.634', 'I01.880.853.996.535', '... | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Urinary tract infection caused by Hansenula anomala. | A case of urinary tract infection due to Hansenula anomala is reported. The infection occurred in a cadaver kidney transplant patient who was receiving immuno-suppression therapy. Survey of the literature revealed that human infections due to this organism are rare and its causal relationship in urinary tract infection... | ['Adult', 'Humans', 'Immunosuppression', 'Kidney Transplantation', 'Male', 'Mycoses', 'Opportunistic Infections', 'Pichia', 'Saccharomycetales', 'Urinary Tract Infections'] | 3,065,645 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.450', 'E05.478.610'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['C01.150.703'], ['C01.597', 'C01.610.684', 'C01.925.597'], ['B01.300.107.795.700', 'B01.300.930.600'], ['B01.300.107.795'], ['C01.915', 'C12.777.892', 'C13.3... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Activity and toxicity of carboplatin and iproplatin in relapsed high-grade glioma. | A total of 15 patients with relapsed high-grade glioma were treated with carboplatin (400 mg/m2) or iproplatin (300 mg/m2). All had received previous radiotherapy, and 12 had previously undergone chemotherapy. One of the ten patients treated with carboplatin and one of the five treated with iproplatin achieved a partia... | ['Adult', 'Aged', 'Antineoplastic Agents', 'Brain Neoplasms', 'Carboplatin', 'Glioma', 'Humans', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Organoplatinum Compounds', 'Remission Induction', 'Thrombocytopenia', 'Vomiting'] | 2,013,119 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['D02.257.125'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.65... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Characterization of the F198S prion protein mutation: enhanced glycosylation and defective refolding. | Prion diseases are associated with the accumulation of a misfolded, protease resistant form of the prion protein, PrPres. In humans there are a variety of different prion related diseases that are sporadic, inherited, or acquired by infection. Gerstmann-Straussler-Sheinker syndrome (GSS) is an inherited prion disease i... | ['Amyloid', 'Binding Sites', 'Brain', 'Cell Extracts', 'DNA Mutational Analysis', 'DNA Primers', 'Endopeptidase K', 'Gerstmann-Straussler-Scheinker Disease', 'Glycosylation', 'Humans', 'Immunoprecipitation', 'Point Mutation', 'PrPSc Proteins', 'Prions', 'Protein Conformation', 'Protein Folding', 'Protein Precursors', '... | 15,851,854 | [['D05.500.049', 'D12.776.049'], ['G02.111.570.120'], ['A08.186.211'], ['D20.777.162'], ['E05.393.760.700.300'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D08.811.277.656.300.760.247', 'D08.811.277.656.959.350.247'], ['C01.207.800.350', 'C10.228.228.800.350', 'C10.574.500.425', 'C10.574.843.400', 'C... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessing the efficacy of rescue equipment in lifeguard resuscitation efforts for drowning. | PURPOSE: The whole drowning process usually occurs within seconds to a few minutes. An early rescue may stop and/or prevent most medical complications. Fins, rescue tube, and rescue board (RB) are the equipment most frequently used by lifeguards. Our objective was to compare, in a water rescue quasiexperimental trial, ... | ['Adult', 'Body Mass Index', 'Cardiopulmonary Resuscitation', 'Emergency Responders', 'Equipment and Supplies', 'Fatigue', 'Female', 'Humans', 'Male', 'Manikins', 'Near Drowning', 'Physical Exertion', 'Rescue Work', 'Safety', 'Spain', 'Task Performance and Analysis', 'Time Factors', 'Treatment Outcome'] | 26,782,793 | [['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E02.365.647.110'], ['M01.526.373'], ['E07'], ['C23.888.369'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.897.280.500.545.129.400', 'L01.178.820.090.545.129.400'], ['C26.304.500', 'N06.850.135.69... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 |
Identification of TDRP1 gene and its association with pig reproduction traits. | This study was performed to identify and characterize the pig TDRP1 gene and to investigate its association with reproduction traits. The obtained pig TDRP1 cDNA (713 base pair [bp]) comprises a 561-bp open reading frame, which encodes a peptide of 187 amino acids. The identities of pig TDRP1 cDNA were 84.6%, 75.7%, an... | ['Alleles', 'Animals', 'Female', 'Genome', 'Male', 'Nuclear Proteins', 'Organ Specificity', 'Polymorphism, Single Nucleotide', 'RNA, Messenger', 'Reproduction', 'Sus scrofa'] | 21,823,921 | [['G05.360.340.024.340.030'], ['B01.050'], ['G05.360.340'], ['D12.776.660'], ['G07.650'], ['G05.365.795.598'], ['D13.444.735.544'], ['G08.686.784'], ['B01.050.150.900.649.313.500.880.399']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bladder shape and racial origin. | The shape of the full bladder was studied during the course of 70 consecutive normal intravenous urograms. A conical or pear-shaped bladder was more frequently seen in patients of black African origin than in white Northern Europeans and more frequently in males than in females. This configuration was found in the abse... | ['Adult', 'African Continental Ancestry Group', 'Continental Population Groups', 'European Continental Ancestry Group', 'Female', 'Humans', 'Male', 'Radiography', 'Sex Factors', 'Ureter', 'Urinary Bladder'] | 4,064,527 | [['M01.060.116'], ['M01.686.508.100'], ['M01.686.508'], ['M01.686.508.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700'], ['N05.715.350.675', 'N06.850.490.875'], ['A05.810.776'], ['A05.810.890']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of methods of measuring glomerular and nutrient blood flow in rat kidneys. | In normal rats, glomerular plasma flow rates (GPF) were estimated from the uptake of microspheres, and single-nephron filtration rates were estimated by Hanssen's technique in order to calculate single-nephron filtration fractions (SNFF) for outer (C1), middle, (C2), and deep (C3) nephrons. With large microspheres (15 ... | ['Animals', 'Female', 'Glomerular Filtration Rate', 'Inulin', 'Kidney', 'Methods', 'Microspheres', 'Rats', 'Regional Blood Flow', 'Rubidium', 'p-Aminohippuric Acid'] | 727,280 | [['B01.050'], ['E01.370.390.400.300', 'G08.852.357'], ['D05.750.078.562.855.750', 'D09.301.915.750', 'D09.698.350.500', 'D09.698.365.855.750'], ['A05.810.453'], ['E05.581'], ['E07.565'], ['B01.050.150.900.649.313.992.635.505.700'], ['G09.330.100.780'], ['D01.268.549.650', 'D01.268.556.800', 'D01.552.528.759', 'D01.552.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Polyol concentrations in the fluid compartments of the human conceptus during the first trimester of pregnancy: maintenance of redox potential in a low oxygen environment. | Polyols are sugar alcohols formed by the reduction of aldoses and ketoses. Production is favored under conditions of low oxygenation, when it may provide an alternative means to production of lactate for regulating the oxidation-reduction balance of pyridine nucleotides. Polyols also act as important organic osmolytes ... | ['Embryo, Mammalian', 'Female', 'Fetus', 'Fructose', 'Galactose', 'Gestational Age', 'Glucose', 'Glycerol', 'Humans', 'Inositol', 'Mannose', 'Oxidation-Reduction', 'Oxygen Consumption', 'Polymers', 'Pregnancy', 'Pregnancy Trimester, First', 'Sorbitol'] | 15,562,012 | [['A16.254'], ['A16.378'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['D09.947.875.359.377'], ['G07.345.500.325.235.968', 'G08.686.320'], ['D09.947.875.359.448'], ['D02.033.800.875.500', 'D09.853.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.033.800.519', 'D09.853.519'], ['D09.947.875.359.588'... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
An investigation of the pre-injury risk factors associated with children who experience traumatic brain injury. | BACKGROUND AND OBJECTIVE: Traumatic brain injury (TBI) is a frequently occurring event in childhood that may have significant ongoing effects. Little is known about the child and family characteristics that predispose children to these injuries. A greater understanding of the risk factors associated with childhood TBI ... | ['Adolescent', 'Adult', 'Brain Injuries', 'Child', 'Child Behavior Disorders', 'Child of Impaired Parents', 'Child, Preschool', 'Depression', 'Epidemiologic Methods', 'Family Characteristics', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Maternal Age', 'New Zealand', 'Parenting', 'Sex Factors', 'Socioecono... | 20,179,033 | [['M01.060.057'], ['M01.060.116'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['M01.060.406'], ['F03.625.141'], ['M01.106'], ['M01.060.406.448'], ['F01.145.126.350'], ['E05.318', 'N06.850.520'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Tacrine improves working memory deficit caused by permanent occlusion of bilateral common carotid arteries in rats. | Effect of tacrine, a cholinesterase inhibitor, on spatial acquisition deficit caused by permanent occlusion of bilateral common carotid arteries (2VO) was examined by using the conventional 8-arm and the 4-arm baited radial maze tasks in rats. Daily administration of tacrine (0.1 and 0.3 mg/kg, i.p.) 1 month after 2VO ... | ['Animals', 'Carotid Artery, Common', 'Carotid Stenosis', 'Cholinesterase Inhibitors', 'Disease Models, Animal', 'Injections, Intraperitoneal', 'Ligation', 'Male', 'Maze Learning', 'Memory', 'Memory Disorders', 'Nootropic Agents', 'Rats', 'Rats, Wistar', 'Spatial Behavior', 'Tacrine'] | 9,469,652 | [['B01.050'], ['A07.015.114.186.200'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.319.267.530.490'], ['E04.426'], ['F02.463.425.874.500'], ['F02.463.425.540'], ... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fates of the blastomeres of the 32-cell stage Pleurodeles waltl embryo. | Cell fate of the blastomeres at the 32-cell stage in the Pleurodeles waltl embryo was analyzed by injection of rhodamine or fluorescein lysinated-dextran (RLDx or FLDx). At the tailbud stage, the progeny of each blastomere contributed to more than one germ layer with unequal distribution along the anteroposterior and d... | ['Animals', 'Blastomeres', 'Cell Line', 'Dextrans', 'Fluorescein-5-isothiocyanate', 'Fluorescent Dyes', 'Pleurodeles', 'Ranidae', 'Rhodamines', 'Xenopus'] | 9,389,450 | [['B01.050'], ['A11.872.700.250.130', 'A16.094'], ['A11.251.210'], ['D05.750.078.562.272', 'D09.698.365.272'], ['D02.455.426.779.347.400', 'D02.500.375.250', 'D02.886.250.250', 'D03.633.300.953.275.400', 'D04.711.347.400'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.090.608.700.540'], ['B01.050.1... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Secure searching of biomarkers through hybrid homomorphic encryption scheme. | BACKGROUND: As genome sequencing technology develops rapidly, there has lately been an increasing need to keep genomic data secure even when stored in the cloud and still used for research. We are interested in designing a protocol for the secure outsourcing matching problem on encrypted data.METHOD: We propose an effi... | ['Biomarkers', 'Cloud Computing', 'Computer Security', 'Data Mining', 'Genomics'] | 28,786,366 | [['D23.101'], ['L01.224.097'], ['L01.224.134', 'N04.452.910.200'], ['L01.313.500.750.280.199', 'L01.470.625'], ['H01.158.273.180.350', 'H01.158.273.343.350']] | ['Chemicals and Drugs [D]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Age, growth and reproductive biology of threatened westslope cutthroat trout Oncorhynchus clarkii lewisi inhabiting small mountain streams. | Age, growth and reproductive characteristics of six westslope cutthroat trout Oncorhynchus clarkii lewisi populations were studied in the south-western Rocky Mountains in Alberta, Canada. Sagittal otoliths were collected from 605 fish ranging in size from 36 to 250 mm (fork length). The maximum detected age (13 years f... | ['Age Factors', 'Animal Distribution', 'Animals', 'Canada', 'Female', 'Male', 'Oncorhynchus', 'Reproduction', 'Rivers'] | 30,198,205 | [['N05.715.350.075', 'N06.850.490.250'], ['F01.145.113.069', 'G16.049'], ['B01.050'], ['Z01.107.567.176'], ['B01.050.150.900.493.817.750.705.580', 'B01.050.150.900.493.817.750.825.580'], ['G08.686.784'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650']] | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[Confounding bias due to indication and severity in observational studies]. | Observational studies are subject to biases that may lead to misinterpretation of the results. This study aimed to determine the influence of omeprazole treatment on the duration of sick leave in patients with ankle sprains treated with non-steroidal anti-inflammatory drugs. We used the Ibermutuamur database. Contrary ... | ['Adult', 'Ankle Injuries', 'Anti-Inflammatory Agents, Non-Steroidal', 'Bias', 'Confounding Factors, Epidemiologic', 'Female', 'Humans', 'Male', 'Omeprazole', 'Retrospective Studies', 'Severity of Illness Index', 'Sick Leave', 'Sprains and Strains'] | 21,376,428 | [['M01.060.116'], ['C26.558.100'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['N05.715.350.150', 'N06.850.490.500'], ['N05.715.350.240', 'N06.850.490.718'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.640.074.500', 'D03.383.725.024.500', 'D03.633.100.103.034.500']... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Genotyping of Toxoplasma gondii strain directly from human CSF samples of congenital toxoplasmosis clinical case. | This report describes a case of congenital toxoplasmosis in a newborn in Southern Italy. A pregnant mother had been admitted at the 20th week of her pregnancy on account of pharyngodynia and laterocervical lymphadenopathy. Although serological testing of the mother's serum documented a seroconversion with positive IgG ... | ['Adult', 'Antibodies, Protozoan', 'Base Sequence', 'Cerebrospinal Fluid', 'DNA, Protozoan', 'Female', 'Genotype', 'Genotyping Techniques', 'Humans', 'Immunoglobulin G', 'Immunoglobulin M', 'Infant, Newborn', 'Polymerase Chain Reaction', 'Polymorphism, Restriction Fragment Length', 'Pregnancy', 'Toxoplasma', 'Toxoplasm... | 28,368,078 | [['M01.060.116'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A12.207.270.210'], ['D13.444.308.442'], ['G05.380'], ['E05.393.442'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
A novel role of hippocalcin in bFGF-induced neurite outgrowth of H19-7 cells. | Hippocalcin is a Ca2+-binding protein that is expressed mainly in pyramidal nerve cells of the hippocampus. However, its functions and mechanism in the brain remain unclear. To elucidate the role of hippocalcin, we used a conditionally immortalized hippocampal cell line (H19-7) and showed that bFGF treatment increased ... | ['Animals', 'Basic Helix-Loop-Helix Transcription Factors', 'Calcium', 'Cell Line, Transformed', 'Chelating Agents', 'Egtazic Acid', 'Enzyme Activation', 'Enzyme Inhibitors', 'Estrenes', 'Fibroblast Growth Factor 2', 'Gene Expression Regulation', 'Hippocalcin', 'Hippocampus', 'Nerve Tissue Proteins', 'Neurites', 'Neuro... | 18,183,620 | [['B01.050'], ['D12.776.260.103', 'D12.776.930.125'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251.210.172'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D02.092.782.258.368.257', 'D02.241.081.018.269'], ['G02.111.263', 'G03.328'], ['D27.505.519.389'], ['D04.210.500.365.415'], ['D12.644.276.624.12... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Attention-sensitive visual event-related potentials elicited by kinetic forms. | Previous event-related potential (ERP) studies have shown that selectively attending to a relevant stimulus feature was associated with selection negativity (SN) components. The present study aimed at investigating the ERP indices of attentional selection based on forms defined by motion (kinetic forms). ERPs were reco... | ['Adult', 'Attention', 'Behavior', 'Brain', 'Brain Mapping', 'Electroencephalography', 'Evoked Potentials', 'Form Perception', 'Humans', 'Male', 'Photic Stimulation'] | 10,210,623 | [['M01.060.116'], ['F02.830.104.214'], ['F01.145'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['F02.463.593.373', 'F02.463.593.778.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genetics of fibrin clot structure: a twin study. | Coronary artery thrombosis following plaque rupture is an important feature of myocardial infarction, and studies have highlighted the role of coagulation in this condition. Although genetic and environmental influences on the variance in coagulation protein concentrations have been reported, there are no data on the h... | ['Adolescent', 'Adult', 'Aged', 'Blood Coagulation', 'Coronary Vessels', 'Diseases in Twins', 'Environment', 'Factor XIII', 'Female', 'Fibrin', 'Fibrinogen', 'Humans', 'Middle Aged', 'Multivariate Analysis', 'Phenotype', 'Thrombosis', 'Time Factors', 'Twins, Dizygotic', 'Twins, Monozygotic'] | 14,604,965 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G09.188.390.150'], ['A07.015.114.269', 'A07.015.908.194'], ['C23.550.291.750'], ['G16.500.275', 'N06.230'], ['D08.622.505', 'D12.776.124.125.475', 'D12.776.811.243.505', 'D23.119.475'], ['D12.776.124.270'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prospective In Vivo Comparison of Damaged and Healthy-Appearing Articular Cartilage Specimens in Patients With Femoroacetabular Impingement: Comparison of T2 Mapping, Histologic Endpoints, and Arthroscopic Grading. | PURPOSE: To describe T2 mapping values in arthroscopically determined International Cartilage Repair Society (ICRS) grades in damaged and healthy-appearing articular cartilage waste specimens from arthroscopic femoroacetabular impingement (FAI) treatment. Furthermore, we sought to compare ICRS grades of the specimens w... | ['Adult', 'Arthroscopy', 'Cartilage Diseases', 'Cartilage, Articular', 'Case-Control Studies', 'Female', 'Femoracetabular Impingement', 'Hip Joint', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Prospective Studies', 'Young Adult'] | 27,132,779 | [['M01.060.116'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['C05.182', 'C17.300.182'], ['A02.165.407.150', 'A02.835.583.192'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C05.550.384', 'C23.550.347'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Why we use AT.Lisa multifocals? | In this paper, the authors try to motivate their preference for implanting AT.Lisa Multifocals from all other premium IOL's from the market. It is emphasized, through clinical examples, that their choice comes after a long experience with this type of mul- tifocals IOL's. We make a short presentation of this particular... | ['Contrast Sensitivity', 'Humans', 'Lens Implantation, Intraocular', 'Lenses, Intraocular', 'Patient Satisfaction', 'Phacoemulsification', 'Prosthesis Design'] | 25,842,626 | [['E01.370.380.850.950.500', 'F02.463.593.778.435.110', 'F02.463.593.932.281', 'F02.463.593.932.901.500', 'G14.940.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.540.825.600'], ['E07.632.500.460', 'E07.695.460'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Development of mortality statistics at governmental hospitals, Egypt. | Mortality statistics are of crucial importance to epidemiological research. Sources of mortality data in Egypt are many. The first records are hospital records, which submit its data to health office records and lastly civil register office records. Hospital records include hospital death notification certificate and h... | ['Data Collection', 'Egypt', 'Hospital Mortality', 'Hospitals, Public', 'Humans'] | 17,219,903 | [['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['Z01.058.266.317'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['N02.278.421.510'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.