Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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The Drosophila melanogaster | PIF1 is a 5' to 3' DNA helicase that can unwind double-stranded DNA and disrupt nucleic acid-protein complexes. In Saccharomyces cerevisiae, Pif1 plays important roles in mitochondrial and nuclear genome maintenance, telomere length regulation, unwinding of G-quadruplex structures, and DNA synthesis during break-induce... | ['Animals', 'BRCA2 Protein', 'DNA Helicases', 'DNA Replication', 'DNA-Directed DNA Polymerase', 'Drosophila Proteins', 'Drosophila melanogaster', 'Recombinational DNA Repair', 'Stress, Physiological'] | 31,537,623 | [['B01.050'], ['D12.776.313.249', 'D12.776.624.776.101', 'D12.776.660.105'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['G02.111.225', 'G05.226'], ['D08.811.913.696.445.308.300'], ['D12.776.093.500.462'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G02.111.222.700', 'G05.219.700', 'G05.728.615.612'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Targeting protein tyrosine phosphatase ó after myocardial infarction restores cardiac sympathetic innervation and prevents arrhythmias. | Millions of people suffer a myocardial infarction (MI) every year, and those who survive have increased risk of arrhythmias and sudden cardiac death. Recent clinical studies have identified sympathetic denervation as a predictor of increased arrhythmia susceptibility. Chondroitin sulfate proteoglycans present in the ca... | ['Animals', 'Arrhythmias, Cardiac', 'Calcium', 'Electrocardiography', 'Female', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Transgenic', 'Myocardial Infarction', 'Peptides', 'Receptor-Like Protein Tyrosine Phosphatases, Class 2', 'Receptors, Adrenergic, beta', 'Sympathetic Nervous System'] | 25,639,594 | [['B01.050'], ['C14.280.067', 'C23.550.073'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['B01.050.050.136.500', 'B01.050.150.900.649.3... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term safety and clinical effectiveness of controlled-release metoclopramide in cancer-associated dyspepsia syndrome: a multicentre evaluation. | Patients with cancer frequently report gastrointestinal symptoms such as anorexia, early satiety, nausea, vomiting, and bloating. A reduction of the severity of some of these symptoms would benefit the patient by enhancing quality of life and improving their treatment. Forty-eight patients (25 female and 23 male; mean ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Anorexia', 'Antiemetics', 'Delayed-Action Preparations', 'Dopamine Antagonists', 'Dyspepsia', 'Female', 'Humans', 'Male', 'Metoclopramide', 'Middle Aged', 'Nausea', 'Neoplasms', 'Syndrome', 'Treatment Outcome', 'Vomiting'] | 12,164,105 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C23.888.821.108'], ['D27.505.696.663.050.030', 'D27.505.954.427.095', 'D27.505.954.483.200'], ['D26.255.210', 'E02.319.300.253'], ['D27.505.519.625.150.175', 'D27.505.696.577.150.175'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Patient information and obtaining informed consent in laparoscopic surgery]. | Since the advent of laparoscopic surgery, the number of suits against surgeons has risen. One of the most frequent complaints is the lack of sufficient information. Physicians in France have a formal obligation to provide information in the contractual legal context established since 1936. This notion has been confirme... | ['Cognition', 'Forecasting', 'France', 'Freedom', 'Humans', 'Informed Consent', 'Laparoscopy', 'Patient Education as Topic', 'Physician-Patient Relations', 'Probability', 'Risk Factors', 'Writing'] | 9,773,003 | [['F02.463.188'], ['I01.320'], ['Z01.542.286'], ['I01.880.604.473.380', 'N03.706.437.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.473.650.718', 'I01.880.604.583.427', 'N03.706.437.650.312', 'N03.706.535.489'], ['E01.370.388.250.520', 'E04.502.250.520'], ['I02.233.332.500', 'N02.421.726.407.680'... | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases. | Germ-line transformation via transposable elements is a powerful tool to study gene function in Drosophila melanogaster. However, some inherent characteristics of transposon-mediated transgenesis limit its use for transgene analysis. Here, we circumvent these limitations by optimizing a phiC31-based integration system.... | ['Animals', 'Attachment Sites, Microbiological', 'Base Sequence', 'Computational Biology', 'Cytogenetic Analysis', 'Drosophila melanogaster', 'Gene Targeting', 'Gene Transfer Techniques', 'Integrases', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Sequence Analysis, DNA', 'Transformation, Genetic', 'Transgen... | 17,360,644 | [['B01.050'], ['G05.360.340.024.079'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['H01.158.273.180', 'L01.313.124'], ['E01.370.225.500.385', 'E05.200.500.385', 'E05.242.385', 'E05.393.285'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['E05.393.335'], ['E05.393.350'], ['D08.811.739.500'], ['L0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
The fine venous architecture of the major duodenal papilla in human beings. | After injecting Indian ink or sulphate of barium backwards into the venous trunks that drain the 2nd portion of the duodenum, the author describes 3 venous networks, continuous to the major papilla and which differ in their topography and morphology of their nets. From the functional point of view, he believes that the... | ['Ampulla of Vater', 'Humans', 'Veins'] | 2,260,760 | [['A03.159.183.079.300.950', 'A03.556.124.684.124.236', 'A03.556.875.249.160', 'A03.734.667.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.908']] | ['Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preclinical MRI: Studies of the irradiated brain. | Radiation therapy (RT) plays a central role in the treatment of primary brain tumors. However, despite recent advances in RT treatment, local recurrences following therapy remain common. Radiation necrosis (RN) is a severe, late complication of radiation therapy in the brain. RN is a serious clinical problem often asso... | ['Animals', 'Antibodies, Blocking', 'Biomarkers', 'Brain', 'Brain Neoplasms', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Mice', 'Necrosis', 'Neoplasm Recurrence, Local', 'Nerve Tissue Proteins', 'Neuroprotective Agents', 'Radiation Injuries, Experimental', 'Radiation-Protective Agen... | 29,705,034 | [['B01.050'], ['D12.776.124.486.485.114.143', 'D12.776.124.790.651.114.143', 'D12.776.377.715.548.114.143'], ['D23.101'], ['A08.186.211'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Recurrence rates after treatment of breast cancer with standard radiotherapy with or without additional radiation. | BACKGROUND: Radiotherapy prevents local recurrence of breast cancer after breast-conserving surgery. We evaluated the effect of a supplementary dose of radiation to the tumor bed on the rates of local recurrence among patients who received radiotherapy after breast-conserving surgery for early breast cancer.METHODS: Af... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Breast Neoplasms', 'Combined Modality Therapy', 'Dose-Response Relationship, Radiation', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Mastectomy, Segmental', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Quality... | 11,794,170 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C04.588.180', 'C17.800.090.500'], ['E02.186'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Projections of the somatosensory areas of the cerebral cortex into the thalamic nuclei]. | Results of morphological studies of degenerated fibers indicated that the first somatosensory area of the cortex was connected by the descending cortico-thalamic fibers with the posterior ventral nucleus of the thalamus. The second somatosensory area was simultaneously connected with the caudal portion of the posterior... | ['Afferent Pathways', 'Animals', 'Cats', 'Cerebral Cortex', 'Electrocoagulation', 'Nerve Degeneration', 'Somatosensory Cortex', 'Thalamic Nuclei', 'Time Factors'] | 1,227,606 | [['A08.612.220'], ['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['A08.186.211.200.885.287.500'], ['E02.154.402', 'E04.014.170.402'], ['C23.550.737'], ['A08.186.211.200.885.287.500.670.675', 'A08.186.211.200.885.287.500.814.906'], ['A08.186.211.200.317.826.701'], ['G01.910.857']] | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fire performance of LNG carriers insulated with polystyrene foam. | Analysis of the response of a liquid-full Moss Sphere LNG tank insulated with polystyrene foam to an engulfing LNG fire indicates that current regulatory requirements for pressure relief capacity sufficient to prevent tank rupture are inadequate. The inadequacy of the current requirements stems primarily from two facto... | ['Fossil Fuels', 'Polystyrenes'] | 18,372,107 | [['D20.345', 'N06.230.132.258'], ['D02.455.426.559.389.150.750.800.830', 'D05.750.716.579', 'D25.720.716.579', 'J01.637.051.720.716.579']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Changes in the corpora cavernosa penis in patients with a traumatic lesion of the urethral canal]. | Contrast investigations of corpus cavernosum penis (CCP) have been performed in 42 patients with urethral traumas. A hip-bone fracture and urethral injury were associated with CCP rupture in 76% of the cases. Sexual dysfunction was registered in all the patients, a complete erectile failure occurred in 57.2% of them. I... | ['Adolescent', 'Adult', 'Aged', 'Diatrizoate Meglumine', 'Erectile Dysfunction', 'Humans', 'Male', 'Middle Aged', 'Penis', 'Posture', 'Radiography', 'Rupture', 'Time Factors', 'Urethra'] | 7,941,160 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D02.033.800.813.550.500', 'D02.241.223.100.400.880.270.500', 'D02.455.426.559.389.127.375.880.270.500', 'D09.067.342.600.500', 'D09.853.813.550.500'], ['C12.294.644.486', 'F03.835.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A05... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Arm-domain interactions in AraC. | N-terminal deletions extending beyond the sixth amino acid of the Escherichia coli regulator of the l-arabinose operon, AraC, were found to generate constitutive regulatory behavior of the promoter pBAD. Mutagenesis of the DNA coding for the first 20 amino acids of the protein and screening for constitutives yielded mu... | ['AraC Transcription Factor', 'Arabinose', 'Bacterial Proteins', 'Base Sequence', 'DNA Primers', 'DNA, Bacterial', 'Escherichia coli', 'Escherichia coli Proteins', 'Models, Genetic', 'Models, Molecular', 'Molecular Sequence Data', 'Mutagenesis', 'Mutagenesis, Site-Directed', 'Nucleic Acid Conformation', 'Operon', 'Poin... | 9,600,837 | [['D12.776.097.049', 'D12.776.260.703.099', 'D12.776.930.780.500'], ['D09.947.875.627.166'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.212'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Predicting relationship stability among midlife African American couples. | OBJECTIVE: This study examined predictors of relationship stability over 5 years among heterosexual cohabiting and married African American couples raising an elementary-school-age child. The vulnerability-stress-adaptation model of relationships (Karney & Bradbury, 1995) guided the investigation. Contextual variables ... | ['Adult', 'African Americans', 'Child', 'Educational Status', 'Family Characteristics', 'Female', 'Humans', 'Male', 'Marriage', 'Models, Psychological', 'Parents'] | 22,004,304 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.406'], ['N01.824.196'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.315.500.500', 'I01.240.361.500.500', 'I01.880.853... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Cloning, high-yield expression in Escherichia coli, and purification of biologically active HIV-1 Tat protein. | We have established an expression system for full-length HIV-1 transactivator (Tat) protein in Escherichia coli. By constructing a synthetic gene for high level expression in enteric bacteria, the recombinant protein can be obtained in high yield. Fusion of the Tat sequence to an N-terminal histidine tag allows the rap... | ['Amino Acid Sequence', 'Base Sequence', 'Cloning, Molecular', 'Disulfides', 'Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Gene Expression', 'Gene Products, tat', 'Genes, Reporter', 'Genetic Vectors', 'HIV-1', 'Isopropyl Thiogalactoside', 'Luciferases', 'Magnetic Resonance Spectroscopy', 'Mass Spectrometr... | 8,812,837 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['E05.196.401.402', 'E05.301.300.319'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.297'], ['D12.776.260.755.1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The potentiation of estrogen on insulin-like growth factor I action in MCF-7 human breast cancer cells includes cell cycle components. | To gain insight into the mechanisms involved in the cross-talk between IGF-1 receptor (IGF-1R) and estrogen receptor signaling pathways, we used MCF-7-derived cells (SX13), which exhibit a 50% reduction in IGF-1R expression. Growth of NEO cells (control MCF-7 cells) was stimulated by both IGF-1 and estradiol (E2), and ... | ['Breast Neoplasms', 'Cell Cycle Proteins', 'Cell Division', 'Cyclin D1', 'Cyclin E', 'Drug Synergism', 'Estradiol', 'Female', 'Genes, Reporter', 'Humans', 'Immunoblotting', 'Insulin-Like Growth Factor I', 'Mitogen-Activated Protein Kinases', 'Phosphatidylinositol 3-Kinases', 'Phosphorylation', 'Protein-Serine-Threonin... | 10,967,123 | [['C04.588.180', 'C17.800.090.500'], ['D12.776.167'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D12.644.360.262.150.100', 'D12.776.167.218.150.100', 'D12.776.476.262.150.100', 'D12.776.624.664.700.100'], ['D12.644.360.262.180', 'D12.776.167.218.180', 'D12.776.476.262.180'], ['G07.690.7... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A membrane-associated dimer of acetylcholinesterase from Xenopus skeletal muscle is solubilized by phosphatidylinositol-specific phospholipase C. | The susceptibility to phosphatidylinositol-specific phospholipase C of the membrane associated acetylcholinesterase (AChE) forms of Xenopus laevis skeletal muscle was examined. This treatment released almost all the detergent-soluble AChE species from muscle homogenates. Sucrose gradient analysis showed that the releas... | ['Acetylcholinesterase', 'Animals', 'Membrane Proteins', 'Muscles', 'Solubility', 'Type C Phospholipases', 'Xenopus laevis'] | 3,412,641 | [['D08.811.277.352.100.170.176'], ['B01.050'], ['D12.776.543'], ['A02.633', 'A10.690'], ['G02.805'], ['D08.811.277.352.640.700.700'], ['B01.050.150.900.090.180.610.500.562']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluating seasonal changes of cone photoreceptor structure in the 13-lined ground squirrel. | Cone photoreceptors of the 13-lined ground squirrel (13-LGS) undergo reversible structural changes during hibernation, including cone outer segment disc degeneration and inner segment mitochondria depletion. Here, we evaluated cone structure with adaptive optics scanning light ophthalmoscopy (AOSLO) before, during, and... | ['Animals', 'Female', 'Hibernation', 'Male', 'Microscopy, Electron, Transmission', 'Ophthalmoscopy', 'Photoperiod', 'Retinal Cone Photoreceptor Cells', 'Sciuridae', 'Seasons'] | 30,826,354 | [['B01.050'], ['G07.110.232.889.500', 'G07.410.421.889.500', 'G16.012.500.535.889.500'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['E01.370.380.560'], ['G01.910.675'], ['A08.675.650.850.625.670.100', 'A08.675.650.915.937.670.100', 'A08.800.950.937.670.100', 'A09.371.729.831.625.670.100', 'A11.671.650.850.625.670... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Ethnic Differences in Trabecular Bone Score. | Trabecular bone score (TBS), a noninvasive textural analysis of the lumbar spine dual-energy X-ray absorptiometry (DXA) image, has been shown to predict fractures in Caucasian (CA) populations but has not been thoroughly studied in African-American (AA) populations. The aim of this study was to compare the TBS in AAs a... | ['Absorptiometry, Photon', 'Acetabulum', 'Adult', 'African Americans', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Bone Density', 'Cancellous Bone', 'European Continental Ancestry Group', 'Female', 'Femur Neck', 'Glucocorticoids', 'Humans', 'Lumbar Vertebrae', 'Middle Aged', 'Osteoporotic Fractures', 'Prevalence', 'Ri... | 27,160,503 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['A02.835.232.043.825.108'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G11.427.100'], ['A10.165.265.414'], ['M01.686.508.400'], ['A02.835.232.043.150.510'], ['D06.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Parenteral nutrition-induced gallbladder disease: a reason for early cholecystectomy. | Patients who receive long-term parenteral nutrition have an increased incidence of both calculous and acalculous cholecystitis. In an attempt to establish guidelines for the clinical management of patients with TPN-induced gallbladder disease, we have reviewed the records of 35 patients who have undergone cholecystecto... | ['Adult', 'Child', 'Child, Preschool', 'Cholecystectomy', 'Cholecystitis', 'Cholelithiasis', 'Female', 'Gallbladder Diseases', 'Humans', 'Infant', 'Male', 'Parenteral Nutrition', 'Parenteral Nutrition, Total', 'Postoperative Complications', 'Retrospective Studies', 'Ultrasonography'] | 6,430,112 | [['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['E04.210.120.172'], ['C06.130.564.263'], ['C06.130.409'], ['C06.130.564'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E02.421.505', 'E02.642.500.505'], ['E02.421.505.575', 'E02.642.500.505.750'], ['C23.550.767'], ['E05.318.372.500.500.500... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Renal secretion and hepatic clearance of human multiple renin forms. | Human active renin can be separated into at least five forms by isoelectric focusing. The present study assessed the preferential renal secretion and hepatic degradation of renin forms in humans. The renin form profile of secreted renal renin was determined before transplant in an ex vivo kidney donor perfusion system ... | ['Adult', 'Cadaver', 'Humans', 'Hypertension', 'Isoelectric Focusing', 'Kidney Transplantation', 'Liver', 'Osmolar Concentration', 'Reference Values', 'Renin', 'Tissue Donors'] | 2,246,033 | [['M01.060.116'], ['C23.550.260.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E05.196.401.663', 'E05.301.300.663'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['A03.620'], ['G02.640'], ['E05.978.810'], ['D08.811.277.656.074.500.780', 'D08.811.277.656.300.048.780', 'D08.811.277.6... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Combined effects of trans-10,cis-12 conjugated linoleic acid, propionate, and acetate on milk fat yield and composition in dairy cows. | Diets inducing milk fat depression (MFD) are known to alter ruminal lipid metabolism, leading to the formation of specific isomers [such as trans-10,cis-12 conjugated linoleic acid (CLA)] that inhibit milk fat synthesis in lactating dairy cows. However, ruminal outflow of these isomers does not fully account for the de... | ['Acetates', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Cattle', 'Diet', 'Dietary Fats', 'Duodenum', 'Fatty Acids', 'Female', 'Food Additives', 'Lactation', 'Linoleic Acids, Conjugated', 'Milk', 'Propionates', 'Rumen'] | 21,426,996 | [['D02.241.081.018', 'D10.251.400.045'], ['G07.203.650.161'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G07.203.650.240'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['A03.556.124.684.124', 'A03.556.875.249'], ['D10.251'], ['D27.720.372.300', 'G07.203.300.514.500', 'J02.500.514.500'], ['G08.686.52... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Value of panel reactive antibodies (PRA) as a guide to the treatment of hyperimmunized patients in renal transplantation. | Patient presensitization represents a considerable problem in candidacy for renal transplantation. While it is well known that hyperimmunized patients--panel reactive antibody (PRA) higher than 60%--create difficulties in donor matching and have a worse outcome than non-hyperimmunized patients, less information is avai... | ['Adolescent', 'Adult', 'Antilymphocyte Serum', 'Blood Transfusion', 'Child', 'Child, Preschool', 'Cytotoxicity, Immunologic', 'Female', 'Follow-Up Studies', 'Graft Survival', 'Histocompatibility Testing', 'Humans', 'Immunosuppressive Agents', 'Infant', 'Isoantibodies', 'Kidney Transplantation', 'Male', 'Middle Aged', ... | 14,621,731 | [['M01.060.057'], ['M01.060.116'], ['A12.207.152.846.500.203', 'D12.776.124.486.485.114.573.203', 'D12.776.124.790.651.114.573.203', 'D12.776.377.715.548.114.573.203', 'D20.215.401.203'], ['E02.095.135'], ['M01.060.406'], ['M01.060.406.448'], ['G12.287'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The Maori, behavior, modern diets and colorectal cancers. | Variation in diet and the rates of colorectal cancers have confounded researchers in recent years. Comparisons of populations in different geographic locations and of different ethnic origins have shown considerable differences in disease frequency, location and relation to diet. This paper revisits an earlier comparis... | ['Colorectal Neoplasms', 'Defecation', 'Diet', 'Feces', 'Female', 'Humans', 'Male', 'New Zealand', 'Oceanic Ancestry Group', 'Posture', 'Urination'] | 22,799,394 | [['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['G10.261.165'], ['G07.203.650.240'], ['A12.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.639.760.747', 'Z01.678.100.747'], ['M01.686.508.600'], ['G11.427.695'... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
[Study on ecoregion techniques of lake nutrients in Yunnan-Guizhou plateau Lake regions]. | The primary objective of this research is to present an ecoregion model based on the principle components analysis (PCA), the cluster analysis (CA), the discriminant analysis (DA) and the spatial autocorrelation analysis (SAA), which were applied to establish the ecorigion of lake nutrients in Yunnan-Guizhou Plateau La... | ['Altitude', 'China', 'Cluster Analysis', 'Ecology', 'Ecosystem', 'Environmental Monitoring', 'Eutrophication', 'Fresh Water', 'Water Pollution'] | 21,250,439 | [['G16.500.275.058', 'N06.230.058'], ['Z01.252.474.164'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['H01.158.273.248', 'H01.277.249'], ['G16.500.275.157', 'N06.230.124'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G16.500.285'], ['G16.500.275.280', 'N06.230.232'], ['N06.850.460.790']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
[Optimization immobilizing activated carbon and bacteria by sodium alginate and its character of adsorption of Pb2+]. | Through the immobilized biosorption of activated carbon and Paenibacillus polymyxa GA1 by sodium alginate, this paper take advantage of the orthogonal experiment to investigate the adsorption characteristics of sodium alginate. According to the research, the optimal preparation conditions were as following: the mass fr... | ['Adsorption', 'Alginates', 'Biodegradation, Environmental', 'Charcoal', 'Environmental Pollutants', 'Glucuronic Acid', 'Hexuronic Acids', 'Immobilization', 'Lead', 'Paenibacillus'] | 21,250,452 | [['G01.030', 'G02.020'], ['D09.698.068'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D01.268.150.150'], ['D27.888.284'], ['D02.241.081.844.915.162.249', 'D02.241.152.811.162.500', 'D02.241.511.902.915.162.500', 'D09.811.922.162.500'], ['D02.241.081.844.915.400', 'D02.241.152.811.400', 'D02.241.511.902.915.400', ... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The role of tissue factor and P-selectin in the procoagulant response that occurs in the first month after on-pump and off-pump coronary artery bypass grafting. | BACKGROUND: It has been previously shown that a persistent (up to 1 month) prothrombotic status occurs after coronary bypass surgery performed both on pump and off pump. To assess the pathways involved in the occurrence of postoperative prothrombotic state, in this study we evaluated plasma, monocyte-bound, and platele... | ['Aged', 'Blood Coagulation', 'Coronary Artery Bypass', 'Coronary Artery Bypass, Off-Pump', 'Female', 'Humans', 'Male', 'Middle Aged', 'P-Selectin', 'Thromboplastin', 'Time Factors'] | 16,307,999 | [['M01.060.116.100'], ['G09.188.390.150'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E04.100.376.719.332.199', 'E04.100.814.868.750.199', 'E04.928.220.520.220.189'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D12.776.395.550.200.700.775', 'D12.776.395.550.625.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ultrasound-guided miduterine cavity embryo transfer is associated with a decreased incidence of retained embryos in the transfer catheter. | After initiating a policy of ultrasound-guided miduterine cavity embryo transfer (ET) on August 1, 2001, the incidence of retained embryos in the transfer catheter declined significantly from 4.2% (46 of 1,101 ETs) during the time interval January 1, 2000 to July 31, 2001, to 0.7% (6 of 908 ETs) during the time interva... | ['Catheterization', 'Confidence Intervals', 'Embryo Transfer', 'Embryo, Mammalian', 'Endosonography', 'Female', 'Humans', 'Incidence', 'Multivariate Analysis', 'Odds Ratio', 'Pregnancy', 'Retrospective Studies', 'Uterus'] | 16,275,257 | [['E02.148', 'E05.157'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E02.875.800.500', 'E05.820.800.500'], ['A16.254'], ['E01.370.350.850.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.98... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Longitudinal versus radial effects of hydroxypropylmethylcellulose on gastrointestinal glucose absorption in dogs. | Many water soluble fibers have been shown to favorably affect the postprandial glucose profile in humans. Hydroxypropylmethylcellulose (HPMC), a fiber which has been shown to increase glucose tolerance in dogs and noninsulin dependent diabetics, was chosen to study the luminal interactions which mediate this effect. Th... | ['Animals', 'Blood Glucose', 'Dietary Fiber', 'Dogs', 'Female', 'Gastrointestinal Transit', 'Glucose', 'Hypromellose Derivatives', 'Intestinal Absorption', 'Methylcellulose', 'Osmolar Concentration', 'Solutions', 'Viscosity'] | 10,379,044 | [['B01.050'], ['D09.947.875.359.448.500'], ['D09.301.416', 'G07.203.300.400', 'J02.500.400'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.372.310', 'G10.261.360.525'], ['D09.947.875.359.448'], ['D05.750.078.562.180.357', 'D09.698.365.180.455', 'D25.720.099.500.719', 'J01.637.051.720.099.500.719'], ['G03.015.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Risks and rewards of using prepaid vs. postpaid incentive checks on a survey of physicians. | BACKGROUND: Survey researchers use monetary incentives as a strategy to motivate physicians' survey participation. Experiments from general population surveys demonstrate that prepaid incentives increase response rates and lower survey administration costs relative to postpaid incentives. Experiments comparing these tw... | ['Adult', 'Cost-Benefit Analysis', 'Female', 'Humans', 'Male', 'Middle Aged', 'Motivation', 'Patient Participation', 'Patient Selection', 'Physicians', 'Reimbursement, Incentive', 'Reward', 'Risk Factors', 'Surveys and Questionnaires', 'Time Factors'] | 30,305,049 | [['M01.060.116'], ['N03.219.151.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.658', 'F01.752.543.500.750'], ['F01.100.150.750.500.620', 'F01.145.488.887.500.620', 'N02.421.143.212.300', 'N03.540.245.360.300', 'N05.300.150.800.500.620'], ['E05.581.500.653', 'N04.590.731'], ['M01.526.... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Asymmetric and Diffuse Uptake of Left Femur in a 3-Year-Old Child Bone Scan: An Unusual Aspect in Acute Lymphoblastic Leukemia. | Acute leukemia is a severe disease frequently encountered in childhood, often diagnosed in later stages because of nonspecific symptoms. It is known to produce uptake in bone scan, and previously described patterns have shown symmetrical abnormalities. However, we report the unusual aspect of the bone scan in a 3-year-... | ['Child, Preschool', 'Femur', 'Humans', 'Male', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'Radionuclide Imaging', 'Radiopharmaceuticals'] | 26,447,375 | [['M01.060.406.448'], ['A02.835.232.043.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.428.600', 'C15.604.515.560.600', 'C20.683.515.528.600'], ['E01.370.350.710', 'E01.370.384.730'], ['D27.505.259.843', 'D27.505.519.871', 'D27.720.470.410.650']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Randomized controlled trial of an implantable continuous hemodynamic monitor in patients with advanced heart failure: the COMPASS-HF study. | OBJECTIVES: The purpose of this study was to determine whether a heart failure (HF) management strategy using continuous intracardiac pressure monitoring could decrease HF morbidity.BACKGROUND: Patients with HF may experience frequent decompensations that require hospitalization despite intensive treatment and follow-u... | ['Adult', 'Aged', 'Blood Pressure Determination', 'Blood Pressure Monitors', 'Female', 'Heart Failure', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Monitoring, Physiologic', 'Prostheses and Implants', 'Severity of Illness Index', 'Single-Blind Method', 'Ventricular Pressure'] | 18,342,224 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.370.140', 'E01.370.600.100'], ['E07.230.740.100'], ['C14.280.434'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.520'], ['E07.695'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.52... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Choice of operative procedure in early gastric cancer]. | Early gastric cancer, i.e., a tumor of intestinal or diffuse cell type confined to the mucosa or submucosa, has so far been found in only 6% of all cases of gastric carcinoma in Europe, whereas the Japanese report a percentage of 30%. This tumor stage has a very good prognosis with a survival rate of 95% or 87%. If the... | ['Humans', 'Stomach Neoplasms'] | 7,169,900 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.249.767', 'C06.405.748.789']] | ['Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stakeholder perceptions of a total market approach to family planning in Viet Nam. | Viet Nam has high modern contraceptive prevalence (68%), with most services received through the public sector. As the country transitions to middle-income status, Viet Nam's donors have ceased donations of contraceptive supplies, causing a large projected shortfall in the family planning budget. In response, the Minis... | ['Adolescent', 'Adult', 'Contraception', 'Delivery of Health Care', 'Family Planning Services', 'Goals', 'Health Policy', 'Health Services Accessibility', 'Humans', 'Middle Aged', 'Privatization', 'Public-Private Sector Partnerships', 'Surveys and Questionnaires', 'Vietnam', 'Young Adult'] | 21,111,350 | [['M01.060.057'], ['M01.060.116'], ['E02.875.194'], ['N04.590.374', 'N05.300'], ['N02.421.143.401', 'N02.421.800.249'], ['F01.658.500'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Platelet monoamine oxidase in chronic schizophrenic patients. | The authors investigated platelet monoamine (MAO) activity in 40 chronic schizophrenic patients, 55 normal control subjects, and 16 hospitalized control subjects. The mean platelet MAO activity for the chronic schizophrenic patients was significantly lower than the mean in either control group. There were no significan... | ['Adult', 'Blood Platelets', 'Chronic Disease', 'Hospitalization', 'Humans', 'Male', 'Monoamine Oxidase', 'Schizophrenia', 'Schizophrenia, Paranoid'] | 618,534 | [['M01.060.116'], ['A11.118.188', 'A15.145.229.188'], ['C23.550.291.500'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.682.664.750'], ['F03.700.750'], ['F03.700.750.600']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Life course theory as a framework to examine becoming a mother of a medically fragile preterm infant. | Life course theory, a sociological framework, was used to analyze the phenomenon of becoming a mother, with longitudinal narrative data from 34 women who gave birth prematurely after a high-risk pregnancy, and whose infant became medically fragile. Women faced challenges of mistimed birth and mothering a technologicall... | ['Adaptation, Psychological', 'Adolescent', 'Adult', 'Biomedical Technology', 'Chronic Disease', 'Decision Making', 'Female', 'Human Development', 'Humans', 'Infant, Newborn', 'Infant, Premature', 'Internal-External Control', 'Longitudinal Studies', 'Male', 'Models, Psychological', 'Mother-Child Relations', 'Object Att... | 18,726,937 | [['F01.058'], ['M01.060.057'], ['M01.060.116'], ['J01.897.120.050'], ['C23.550.291.500'], ['F02.463.785.373'], ['F01.525', 'G07.345.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['F01.829.379'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.5... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'G... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Hind limb proportions and kinematics: are small primates different from other small mammals? | Similar in body size, locomotor behaviour and morphology to the last common ancestor of Primates, living small quadrupedal primates provide a convenient model for investigating the evolution of primate locomotion. In this study, the hind limb kinematics of quadrupedal walking in mouse lemurs, brown lemurs, cotton-top t... | ['Age Factors', 'Animals', 'Biological Evolution', 'Biomechanical Phenomena', 'Body Weights and Measures', 'Female', 'Hindlimb', 'Locomotion', 'Male', 'Mammals', 'Models, Theoretical', 'Species Specificity'] | 16,109,897 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['G05.045', 'G16.075'], ['G01.154.090', 'G01.374.089'], ['E01.370.600.115.100', 'E05.041.124', 'G07.100.100'], ['A13.473'], ['G07.568.500', 'G11.427.410.568'], ['B01.050.150.900.649'], ['E05.599'], ['G16.824']] | ['Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Operative lengthening of the femur. | Femoral lengthening with the aid of the apparatus described in this article can be accomplished safely and predictably. However, it is not without considerations and problems which must be fully understood and appreciated. The healing process requires months to years; with a cooperative patient and a diligent attentive... | ['Adolescent', 'Bone Lengthening', 'Child', 'Female', 'Femur', 'Hip Dislocation', 'Humans', 'Knee', 'Leg Length Inequality', 'Male', 'Postoperative Care', 'Postoperative Complications', 'Time Factors'] | 729,276 | [['M01.060.057'], ['E04.555.120'], ['M01.060.406'], ['A02.835.232.043.150'], ['C05.550.518.384', 'C26.289.384', 'C26.531.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.450'], ['C05.116.099.655', 'C23.300.808'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.722.700'], ['C23.550.767'], ['G01.910.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Head injuries following television-related accidents in the pediatric population. | OBJECT: Current data indicate the rate of head injuries in children caused by falling televisions is increasing. The authors describe these injuries and the cost incurred by them.METHODS: In a single-institution retrospective review, all children treated for a television-related injury at LeBonheur Children's Hospital,... | ['Accidents, Home', 'Age Distribution', 'Arkansas', 'Brain Concussion', 'Catchment Area, Health', 'Child', 'Child, Preschool', 'Cost of Illness', 'Female', 'Glasgow Coma Scale', 'Head Injuries, Closed', 'Hospitalization', 'Hospitals, Pediatric', 'Humans', 'Infant', 'Male', 'Mississippi', 'Missouri', 'Retrospective Stud... | 25,084,085 | [['N06.850.135.217'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['Z01.107.567.875.750.110'], ['C10.228.140.199.444.250', 'C10.900.300.087.235.250', 'C10.900.300.350.300', 'C26.915.300.200.194.250', 'C26.915.300.450.500', 'C26.974.382.200'], ['N01.224.791.200', 'N03.349.650.095', 'N06.850.505.400.800.200'],... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
The use of peritoneal dialysis as a means of supplying nutrients. | The aim of this study is to demonstrate the possibility of using the peritoneal route for carrying out periodical dialysis (PPD) together with supplying amino acids (AA's) for nutritional purposes and, at the same time, to determine the influence of the pattern of the mixture of AA's used for this purpose. In order to ... | ['Acute Kidney Injury', 'Amino Acids', 'Catheters, Indwelling', 'Humans', 'Kidney Failure, Chronic', 'Peritoneal Dialysis'] | 3,570,454 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['D12.125'], ['E07.132.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E02.870.300.650', 'E02.912.800.650']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electrical source localization of human movement-related cortical potentials. | Movement-related cortical potentials (MRCP) of healthy humans were analyzed with a brain electrical source analysis program for modelling equivalent electrical dipoles in order to suggest the generators of the MRCP. Both right and left voluntary self-paced index finger movements were performed by 14 subjects and MRCP w... | ['Adult', 'Brain Mapping', 'Cerebral Cortex', 'Electroencephalography', 'Electromyography', 'Electrophysiology', 'Female', 'Fingers', 'Humans', 'Male', 'Models, Biological', 'Motor Cortex', 'Movement', 'Somatosensory Cortex'] | 8,206,807 | [['M01.060.116'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['E01.370.376.300', 'E01.370.405.245'], ['E01.370.405.255', 'E01.370.530.255'], ['H01.158.344.528', 'H01.158.782.236'], ['A01.378.800.667.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Analysis of transcripts of genes located within the HLA-D region in B cells from an HLA-severe combined immunodeficiency individual. | The mRNA levels of LMP7, HLA-DMA, and HLA-DMB genes, all located within the HLA-D region, were analyzed in the "bare lymphocyte" line SJO, which had been shown to be characterized by a transcription defect of class II genes (DP, DQ, and DR). This was done using semiquantitative PCR amplification of cDNA generated from ... | ['Base Sequence', 'Cell Line', 'Genes, MHC Class II', 'HLA-D Antigens', 'Humans', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'RNA, Messenger', 'Severe Combined Immunodeficiency'] | 8,106,283 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['G05.360.340.024.340.610.600', 'G05.360.340.024.380.500.600', 'G12.500.500.600'], ['D12.776.395.550.509.400', 'D12.776.543.550.440.400', 'D23.050.301.500.400.400', 'D23.050.301.500.450.400', 'D23.050.705.552.410.400', 'D23.050.705.552.450.400... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The presence of high-grade prostatic intraepithelial neoplasia or atypia on prostate biopsy does not adversely affect prostatectomy outcomes for patients otherwise eligible for active surveillance. | OBJECTIVE: To investigate if the presence of concomitant high-grade prostatic intraepithelial neoplasia (HGPIN) or atypical small acinar proliferation (ASAP) on biopsy increases the risk of occult adverse pathology in patients otherwise suitable for active surveillance (AS).METHODS: Patients with D'Amico low-risk prost... | ['Aged', 'Analysis of Variance', 'Biopsy, Needle', 'Cohort Studies', 'Disease-Free Survival', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Grading', 'Neoplasm Invasiveness', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Patient Selection', 'Prognosis', 'Prospective St... | 25,288,572 | [['M01.060.116.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['E05.318.372.500.750', 'N05.715.360.330.500.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Native chicken gizzard tropomyosin is predominantly a beta gamma-heterodimer. | Unmodified chicken gizzard tropomyosin (TM) has been fractionated into its two major isoforms beta and gamma, by chromatofocussing in the presence of 9 M urea and dithiothrieitol. Treatment of the native protein with several bifunctional N-hydroxysuccinimide esters gave the beta gamma-heterodimer as the major cross-lin... | ['Animals', 'Chickens', 'Chromatography, High Pressure Liquid', 'Dithiothreitol', 'Electrophoresis, Polyacrylamide Gel', 'Gizzard, Avian', 'Isoelectric Focusing', 'Macromolecular Substances', 'Temperature', 'Tropomyosin'] | 3,745,212 | [['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.196.181.400.300'], ['D02.033.800.196', 'D02.886.740.224', 'D09.853.196'], ['E05.196.401.402', 'E05.301.300.319'], ['A13.853.355'], ['E05.196.401.663', 'E05.301.300.663'], ['D05'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Extraction and GLC analysis of pyrithyldione in highly putrified human postmortem samples. | Pyrithyldione was isolated from highly putrified human brain and small intestine samples by ether extraction followed by alumina column cleanup. The total yield was 90+/- 5%. No derivatization was necessary prior to GLC analysis. | ['Autopsy', 'Chromatography, Gas', 'Forensic Medicine', 'Humans', 'Hypnotics and Sedatives', 'Methods', 'Postmortem Changes', 'Pyridones'] | 966,162 | [['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E05.196.181.349'], ['H02.403.330', 'I01.198.780.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.277.350', 'D27.505.954.427.210.350'], ['E05.581'], ['C23.550.260.224.617'], ['D03.383.725.791']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Restricted feedback control in discrete-time dynamical systems with memory. | When an equilibrium state of a physical or biological system suffers a loss of stability (e.g., via a bifurcation), it may be both possible and desirable to stabilize the equilibrium via closed-loop feedback control. Significant effort has been devoted towards using such control to prevent oscillatory or chaotic behavi... | ['Action Potentials', 'Animals', 'Computer Simulation', 'Feedback, Physiological', 'Heart Conduction System', 'Heart Rate', 'Humans', 'Models, Cardiovascular'] | 24,827,309 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['L01.224.160'], ['G07.410.732'], ['A07.541.409'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.161']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Diurnal variations in insulin secretion and insulin sensitivity in aged subjects. | Glucose tolerance tends to decrease in healthy aged subjects without family history of diabetes. Either reduced insulin secretion or insulin resistance may be responsible. Insulin secretion and insulin sensitivity were studied in 7 aged subjects (68-75 years) and 8 young controls (21-27 years). A 1-mg i.v. glucagon and... | ['Adult', 'Age Factors', 'Aged', 'Arginine', 'Blood Glucose', 'Circadian Rhythm', 'Fatty Acids, Nonesterified', 'Glucagon', 'Humans', 'Insulin', 'Insulin Secretion', 'Kinetics'] | 7,004,042 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D09.947.875.359.448.500'], ['G07.180.562.190'], ['D10.251.310'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of facility characteristics on the social adjustment of mentally ill residents of board-and-care homes. | Data from a survey of 851 mentally ill residents of 210 board-and-care homes in seven states were used to assess the extent to which facility characteristics such as size, rate of resident turnover, operation for profit, cost of care, staffing ratios, and location of the home encourage resident activity or permit resid... | ['Activities of Daily Living', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cost-Benefit Analysis', 'Data Collection', 'Female', 'Halfway Houses', 'Health Facilities', 'Health Facility Environment', 'Humans', 'Male', 'Mental Disorders', 'Middle Aged', 'Psychological Tests', 'Social Adjustment', 'Statistics as T... | 3,147,941 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N03.219.151.125'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['J03.775.450'], ['N02.278'], ['N02.278.220', 'N05.300.430.400'], ['B01.05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occup... | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
[A clinical case of complicated tuberculosis in an infant from perinatal contact with HIV infection]. | The paper describes a case of tuberculosis of intrathoracic lymph nodes in a baby born to a HIV-infected mother. The baby developed a severe tuberculous process complicated by bronchopulmonary lesion and by the ulcerofistular form of bronchial tuberculosis accompanied by bacterial isolation. The infant had been in cont... | ['Adult', 'Antitubercular Agents', 'Disease Progression', 'Female', 'HIV', 'HIV Infections', 'Humans', 'Infant', 'Male', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Radiography, Thoracic', 'Tuberculin Test', 'Tuberculosis, Lymph Node'] | 16,318,264 | [['M01.060.116'], ['D27.505.954.122.085.255'], ['C23.550.291.656'], ['B04.820.650.589.650.350'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G08.686.784.769'], ['C01.674', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Changes in dendritic axial resistance alter synaptic integration in cerebellar Purkinje cells. | The ability of neurons to process synaptic inputs depends critically on their passive electrical properties. The intracellular resistivity, R(i), is one of the parameters that determine passive properties, yet few experiments have explored how changes in R(i) might affect synaptic integration. In this work, I addressed... | ['Animals', 'Dendrites', 'Female', 'Glass', 'Male', 'Models, Biological', 'Pressure', 'Purkinje Cells', 'Rats', 'Rats, Wistar', 'Synapses', 'Synaptic Potentials'] | 21,354,392 | [['B01.050'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['J01.637.437'], ['E05.599.395'], ['G01.374.715'], ['A08.186.211.132.810.428.200.212.600', 'A08.675.784', 'A11.671.784'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['A08.850', 'A11.284.149.165.420.780'],... | ['Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Wide inter-individual variability of bispectral index and spectral entropy at loss of consciousness during increasing concentrations of dexmedetomidine, propofol, and sevoflurane. | BACKGROUND: The bispectral index (BIS) and the spectral entropy (state entropy, SE, and response entropy, RE) are depth-of-anaesthesia monitors derived from EEG and have been developed to measure the effects of anaesthetics on the cerebral cortex. We studied whether they can differentiate consciousness from unconscious... | ['Adult', 'Anesthesia Recovery Period', 'Anesthesia, General', 'Anesthetics, Inhalation', 'Anesthetics, Intravenous', 'Consciousness Monitors', 'Data Interpretation, Statistical', 'Dexmedetomidine', 'Dose-Response Relationship, Drug', 'Entropy', 'Humans', 'Hypnotics and Sedatives', 'Male', 'Methyl Ethers', 'Propofol', ... | 21,733,891 | [['M01.060.116'], ['E03.160', 'E04.614.750.055', 'N02.421.585.753.750.055'], ['E03.155.197'], ['D27.505.696.277.100.035.060', 'D27.505.954.427.210.100.035.060'], ['D27.505.696.277.100.035.075', 'D27.505.954.427.210.100.035.075'], ['E07.858.195'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.36... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Gallium arsenide differentially affects processing of phagolysosomal targeted antigen by macrophages. | Gallium arsenide, a semiconductor utilized in the electronics industry, causes immunosuppression in animals. The chemical's effect on macrophages to process antigen for activating pigeon cytochrome-specific helper T cell hybridoma was investigated. Mice were administered 200 mg/kg gallium arsenide or vehicle intraperit... | ['Animals', 'Antigen-Presenting Cells', 'Arsenicals', 'Cell Line', 'Columbidae', 'Cytochalasin D', 'Cytochrome c Group', 'Female', 'Gallium', 'Hybridomas', 'Lysosomes', 'Macrophages', 'Macrophages, Peritoneal', 'Mice', 'Mice, Inbred Strains', 'Phagocytosis', 'Phagosomes', 'Spleen', 'T-Lymphocytes'] | 9,500,519 | [['B01.050'], ['A11.066', 'A15.382.066'], ['D01.075', 'D02.129'], ['A11.251.210'], ['B01.050.150.900.248.165.150'], ['D03.633.100.473.231.450', 'D23.946.587.370.450'], ['D08.244.286', 'D12.776.422.220.286'], ['D01.268.556.289', 'D01.552.544.289'], ['A11.251.353.485', 'A11.251.600.485'], ['A11.284.430.214.190.875.190.55... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metastasis of carcinoma to hemangioblastoma cerebelli: case report. | A patient with a long-standing posterior fossa tumor developed symptoms that it was growing rapidly. The increasing growth resulted from secondary prostatic carcinoma complicating the cystic cerebellar hemangioblastoma. | ['Aged', 'Carcinoma', 'Cerebellar Neoplasms', 'Hemangiosarcoma', 'Humans', 'Male', 'Neoplasm Metastasis', 'Prostatic Neoplasms'] | 3,226,519 | [['M01.060.116.100'], ['C04.557.470.200'], ['C04.588.614.250.195.411.211', 'C10.228.140.211.500.200', 'C10.228.140.252.200', 'C10.551.240.250.400.300'], ['C04.557.450.795.390', 'C04.557.645.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650', 'C23.550.727.650'], ['C04.588.945.440.770', 'C12.294.260.7... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Functional morphology of the maxillo-mandibular system in the mini-Lewe minipig. 4. Functional analysis of the masticatory muscles at various ages]. | The percentage of dry weight distribution of the jaw muscles is described, and muscle growth is calculated by means of second degree homogeneous linear differential equations with constant coefficients. The components of the chewing muscles are calculated from the parallelogram of forces on the basis of their dry weigh... | ['Aging', 'Animals', 'Masticatory Muscles', 'Maxillofacial Development', 'Organ Size', 'Swine', 'Swine, Miniature'] | 3,314,594 | [['G07.345.124'], ['B01.050'], ['A02.633.567.600', 'A14.530'], ['G07.345.500.325.377.625.050.500.478', 'G11.427.578.050.500.478'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690'], ['B01.050.150.900.649.313.500.880'], ['B01.050.150.900.649.313.500.880.399.800']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-Term Therapy Outcomes When Treating Chronic Kidney Disease Patients with Paricalcitol in German and Austrian Clinical Practice (TOP Study). | Paricalcitol is approved for prevention and therapy of secondary hyperparathyroidism (sHPT) in patients with chronic kidney disease (CKD), with only short-term data in clinical routine settings. A 12-month observational study was conducted in Germany and Austria (90 centers, 761 patients) from 2008 to 2013. Laboratory ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Austria', 'Biomarkers', 'Bone Density Conservation Agents', 'Calcium', 'Ergocalciferols', 'Female', 'Germany', 'Humans', 'Hyperparathyroidism, Secondary', 'Kidney Failure, Chronic', 'Kidney Function Tests', 'Male', 'Middle Aged', 'Phosphorus', 'Renal Dialysis', 'Renal Insufficien... | 28,956,807 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.542.088'], ['D23.101'], ['D27.505.696.242'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D04.210.500.247.222.474', 'D04.210.500.247.808.412', 'D04.210.500.812.768.462', 'D10.570.938.439'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.4... | ['Named Groups [M]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Clarification of the peripherally located F-actin network around the primary afferent neurons. | The primary afferent neurons are enriched for F-actin in the peripheries, giving rise to ring-like appearances when stained with fluorescence probes for actin. A variety of data, mainly obtained from in vitro experiments, suggested that the satellite cell (SC) envelopes around sensory neurons may be a candidate for the... | ['Actins', 'Animals', 'Connective Tissue', 'Female', 'Ganglia, Spinal', 'Microscopy, Electron, Transmission', 'Nerve Growth Factors', 'Nerve Net', 'Neural Cell Adhesion Molecules', 'Rats', 'Rats, Sprague-Dawley', 'S100 Calcium Binding Protein beta Subunit', 'S100 Proteins', 'Sensory Receptor Cells'] | 21,459,082 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['A10.165'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['D12.644.276.860', 'D12.776.467.860', 'D12.776.631.600', 'D23.529.850'], ['A08.511'], ['D12.776.395.550.20... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Repetitive sessions of tDCS to improve naming in post-stroke aphasia: Insights from an individual patient data (IPD) meta-analysis. | OBJECTIVES: Small clinical trials reported that repetitive sessions of tDCS could improve naming abilities in post-stroke aphasia. However, systematic meta-analyses found no effect, but all of these analyses pooled data from both single and repetitive sessions at the group level. The aim of this paper was to perform a ... | ['Aphasia', 'Databases, Bibliographic', 'Female', 'Humans', 'Male', 'Names', 'Outcome Assessment, Health Care', 'Stroke', 'Transcranial Direct Current Stimulation'] | 29,439,369 | [['C10.597.606.150.500.800.100', 'C23.888.592.604.150.500.800.100'], ['L01.313.500.750.300.188.300', 'L01.470.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.559.598.400.556'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['C10.228.140.300.775', 'C14.907.253.855'], ['E02.331.750'... | ['Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[Spontaneous cholecystocutaneous fistula]. | INTRODUCTION: Spontaneous cholecystocutaneous fistula is now a rare entity due to the advent of antibiotics, ultrasonography, and safe and early surgical treatment of biliary tract diseases. Such a case is reporting here, revealed by the systematic histological examination of the skin biopsy.OBSERVATION: A 65 year-old ... | ['Aged', 'Cutaneous Fistula', 'Gallbladder Diseases', 'Humans', 'Inflammation', 'Intestinal Fistula', 'Male'] | 15,988,360 | [['M01.060.116.100'], ['C17.800.135', 'C23.300.575.150'], ['C06.130.564'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['C06.267.550', 'C06.405.469.471', 'C23.300.575.185.550']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The chemical nature of the polar functional group of oxidized acyl chain uniquely modifies the physicochemical properties of oxidized phospholipid-containing lipid particles. | Oxidative modification of phospholipids generates a variety of oxidized phospholipid (Ox-PL) species which differ considerably in their chemical compositions and molecular structures. Recent results suggest that even closely related Ox-PL species can have considerably different biological effects. However, the molecula... | ['Fatty Acids', 'Membranes, Artificial', 'Oxidation-Reduction', 'Phospholipids'] | 23,673,722 | [['D10.251'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['G02.700', 'G03.295.531'], ['D10.570.755']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Impact of gynecological screening in Lynch syndrome carriers with an MSH2 mutation. | Lifetime risk of developing endometrial cancer in Lynch syndrome carriers is very high and females are also at an increased risk of developing ovarian cancer. The aim of the study was to determine the impact of gynecological screening in MSH2 mutation carriers. Gynecological cancer incidence and overall survival was co... | ['Adult', 'Aged, 80 and over', 'Case-Control Studies', 'Colonoscopy', 'Colorectal Neoplasms, Hereditary Nonpolyposis', 'Endometrial Neoplasms', 'Female', 'Follow-Up Studies', 'Genetic Testing', 'Genital Neoplasms, Female', 'Gynecological Examination', 'Humans', 'Middle Aged', 'MutS Homolog 2 Protein', 'Mutation', 'Ovar... | 22,775,459 | [['M01.060.116'], ['M01.060.116.100.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C04.588.274.476.411.307.190', 'C04.700.250', 'C06.301.371.411.307.190', 'C06.405.249.4... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Glial aromatization decreases neural injury in the zebra finch (Taeniopygia guttata): influence on apoptosis. | Emerging evidence suggests a neuroprotective role for oestrogens following damage to the vertebrate brain. Aromatase (oestrogen synthase) is rapidly transcribed and translated in glial cells around areas of neural damage in several vertebrates. However, the potential neuroprotection afforded by locally up-regulated gli... | ['Animals', 'Apoptosis', 'Aromatase', 'Brain Injuries', 'Down-Regulation', 'Enzyme Inhibitors', 'Fadrozole', 'Male', 'Neuroglia', 'Neurons', 'Songbirds', 'Wounds, Penetrating'] | 15,271,060 | [['B01.050'], ['G04.146.954.035'], ['D08.244.453.489.500', 'D08.244.453.915.099', 'D08.811.682.690.708.170.447.500', 'D08.811.682.690.708.170.915.099', 'D12.776.422.220.453.489.500', 'D12.776.422.220.453.915.099'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['G02.111.240', 'G05.308.200', 'G07.690.773.93... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of the bifunctional Bacillus subtilis TatAd protein in Escherichia coli reveals distinct TatA/B-family and TatB-specific domains. | In the Tat protein export pathway of Gram-negative bacteria, TatA and TatB are homologous proteins that carry out distinct and essential functions in separate sub-complexes. In contrast, Gram-positive Tat systems usually lack TatB and the TatA protein is bifunctional. We have used a mutagenesis approach to delineate Ta... | ['Amino Acid Motifs', 'Amino Acid Sequence', 'Amino Acid Substitution', 'Bacillus subtilis', 'Bacterial Proteins', 'Escherichia coli', 'Genetic Complementation Test', 'Membrane Transport Proteins', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Protein Interaction Domains and Motifs', 'Protein Transport', 'S... | 21,479,530 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['B03... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Psychological characteristics of Swedish mandatory enlisted soldiers volunteering and not volunteering for international missions: an exploratory study. | The purpose of this study was to assess personality traits, psychological fitness, and hardiness among conscript soldiers volunteering for international missions (n = 146), by comparing them with conscripts from the same year class and unit who did not apply for international missions (n = 275). The sample consisted of... | ['Adaptation, Psychological', 'Career Choice', 'Character', 'Female', 'Humans', 'Internationality', 'Male', 'Military Personnel', 'Resilience, Psychological', 'Self Efficacy', 'Surveys and Questionnaires', 'Sweden', 'Volunteers', 'Young Adult'] | 23,833,893 | [['F01.058'], ['F02.463.785.373.346.400'], ['F01.752.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615'], ['M01.526.625'], ['F02.940'], ['F01.752.747.792.700'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['Z01.542.816.500'], ['M01.955'], ['M01.060.116.815']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Sub-unit structure and specificity of methionyl-transfer-ribonucleic acid synthetase from Escherichia coli. | 1. The purification of methionyl-transfer-RNA synthetase from Escherichia coli by a modified technique gives a 16% yield of a protein that appears homogeneous by the criteria of disc gel electrophoresis, ultracentrifugation and end-group analysis. 2. The molecular weight is 96000 and the protein consists of two sub-uni... | ['Amino Acid Sequence', 'Electrophoresis, Disc', 'Escherichia coli', 'Kinetics', 'Ligases', 'Malates', 'Methionine', 'Methods', 'Molecular Weight', 'RNA, Messenger', 'Ultracentrifugation'] | 4,874,971 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.401.402.236', 'E05.301.300.319.403'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G01.374.661', 'G02.111.490'], ['D08.811.464'], ['D02.241.081.337.463', 'D02.241.511.505'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.166.676'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Chronic multisymptom illness among female Veterans deployed to Iraq and Afghanistan. | BACKGROUND: Chronic multisymptom illness (CMI) may be more prevalent among female Operation Enduring Freedom/Operation Iraqi Freedom/Operation New Dawn (OEF/OIF/OND) deployed Veterans due to deployment-related experiences.OBJECTIVES: To investigate CMI-related diagnoses among female OEF/OIF/OND Veterans.RESEARCH DESIGN... | ['Adolescent', 'Adult', 'Afghan Campaign 2001-', 'Chronic Disease', 'Fatigue Syndrome, Chronic', 'Female', 'Fibromyalgia', 'Humans', 'Iraq War, 2003-2011', 'Irritable Bowel Syndrome', 'Middle Aged', 'Prevalence', 'Risk Factors', 'United States', 'Veterans'] | 25,767,968 | [['M01.060.057'], ['M01.060.116'], ['I01.880.735.950.250.094', 'K01.400.504.984.124'], ['C23.550.291.500'], ['C01.925.330', 'C05.651.310', 'C10.228.440.600', 'C10.668.364'], ['C05.651.324', 'C05.799.321', 'C10.668.491.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.735.950.250.782', 'K01.400.504.984.2... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Coronavirus neurovirulence correlates with the ability of the virus to induce proinflammatory cytokine signals from astrocytes and microglia. | The molecular and cellular basis of coronavirus neurovirulence is poorly understood. Since neurovirulence may be determined at the early stages of infection of the central nervous system (CNS), we hypothesize that it may depend on the ability of the virus to induce proinflammatory signals from brain cells for the recru... | ['Animals', 'Astrocytes', 'Cells, Cultured', 'Coronavirus', 'Cytokines', 'Gene Expression Regulation', 'Inflammation Mediators', 'Mice', 'Mice, Inbred C57BL', 'Microglia', 'Oligonucleotide Array Sequence Analysis', 'RNA, Messenger', 'Virulence', 'Virus Replication'] | 15,016,862 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['A11.251'], ['B04.820.578.500.540.150'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G05.308'], ['D23.469'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['A08.637.400', 'A11.6... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Studies on Chlamydomonas chloroplast transformation: foreign DNA can be stably maintained in the chromosome. | As shown originally by Boynton and co-workers (Boynton, J.E., Gillham, N.W., Harris, E.H., Hosler, J.P., Johnson, A.M., Jones, A.R., Randolph-Anderson, B.L., Robertson, D., Klein, T.M., Shark, K.B., and Sanford, J.C. [1988]. Science 240, 1534-1538), a nonphotosynthetic, acetate-requiring mutant strain of Chlamydomonas ... | ['Animals', 'Base Sequence', 'Chlamydomonas reinhardtii', 'Chloroplasts', 'Chromosomes', 'Cloning, Molecular', 'DNA, Recombinant', 'Genetic Complementation Test', 'Molecular Sequence Data', 'Repetitive Sequences, Nucleic Acid', 'Restriction Mapping', 'Transformation, Genetic'] | 2,535,460 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.650.940.150.385.650'], ['A11.284.430.214.190.875.700.140'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['E05.393.220'], ['D13.444.308.460'], ['E05.393.281.526'], ['L01.453.245.667'], ['G02.111.570.080.708', 'G05.360.080.7... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Precision of progesterone measurements with the use of automated immunoassay analyzers and the impact on clinical decisions for in vitro fertilization. | OBJECTIVE: To compare the precision of progesterone measurements obtained with the use of immunoassays and of liquid chromatography-tandem mass spectrometry (LC-MS/MS).DESIGN: Comparative study.SETTING: Academic, private practice, and in vitro fertilization (IVF) research centers.PATIENT(S): A total of 189 human serum ... | ['Automation, Laboratory', 'Biomarkers', 'Chromatography, Liquid', 'Equipment Design', 'Female', 'Fertilization in Vitro', 'Humans', 'Immunoassay', 'Infertility', 'Laboratory Proficiency Testing', 'Observer Variation', 'Ovulation Induction', 'Patient Selection', 'Predictive Value of Tests', 'Pregnancy', 'Pregnancy Rate... | 24,661,729 | [['E05.064', 'J01.897.104.416'], ['D23.101'], ['E05.196.181.400'], ['E05.320'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['C12.294.365', 'C13.351.500.365'], ['J01.897.608.500', 'N04.761.700.512'], ['E01.354.753', 'N02.421.450.600', 'N05.715... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Expression of the soluble vascular endothelial growth factor receptor-1 in cutaneous melanoma: role in tumour progression. | BACKGROUND: Vascular endothelial growth factor (VEGF)-A, placenta growth factor (PlGF) and their corresponding membrane receptors are involved in autocrine and paracrine regulation of melanoma growth and metastasis. Besides the membrane receptors, a soluble form of the VEGF receptor (VEGFR)-1 (sVEGFR-1) has been identi... | ['Cell Line, Tumor', 'Disease Progression', 'Humans', 'Immunohistochemistry', 'Melanoma', 'Neoplasm Proteins', 'Polymerase Chain Reaction', 'Skin Neoplasms', 'Vascular Endothelial Growth Factor Receptor-1'] | 21,198,538 | [['A11.251.210.190', 'A11.251.860.180'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512... | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Expression and significance of Tim-3 on peripheral blood monocytes in patients with chronic hepatitis B]. | OBJECTIVE: To detect T cell immunoglobulin and mucin domain-containing molecule 3(Tim-3) expression on peripheral blood monocyts (PBMs) and explore its effect on inflammatory cytokines production of PBMs in patients with chronic hepatitis B (CHB).METHODS: The expression of Tim-3 protein and mRNA on PBM subsets was resp... | ['Adolescent', 'Adult', 'Aged', 'Alanine Transaminase', 'Cytokines', 'Female', 'Galectins', 'Hepatitis A Virus Cellular Receptor 2', 'Hepatitis B, Chronic', 'Humans', 'Immunophenotyping', 'Leukocytes, Mononuclear', 'Lipopolysaccharide Receptors', 'Male', 'Membrane Proteins', 'Middle Aged', 'RNA, Messenger', 'Receptors,... | 23,837,986 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D08.811.913.477.700.100'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D12.776.503.307'], ['D12.776.395.550.479', 'D12.776.465.798', 'D12.776.543.550.437', 'D12.776.543.750.830.219'], ['C01.221.250.500.100', 'C01.925.256.430.400.100', 'C01.925.440.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Characterisation of the Novel Mixed Mu-NOP Peptide Ligand Dermorphin-N/OFQ (DeNo). | INTRODUCTION: Opioid receptors are currently classified as Mu (ì), Delta (ä), Kappa (ê) plus the opioid related nociceptin/orphanin FQ (N/OFQ) peptide receptor (NOP). Despite compelling evidence for interactions and benefits of targeting more than one receptor type in producing analgesia, clinical ligands are Mu agonis... | ['Animals', 'CHO Cells', 'Calcium', 'Cricetulus', 'Guinea Pigs', 'HEK293 Cells', 'Humans', 'Male', 'Opioid Peptides', 'Peptides', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Opioid', 'Receptors, Opioid, mu'] | 27,272,042 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['B01.050.150.900.649.313.992.550'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.400.575', 'D12.776.631.650.575... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Investigations on the endoparasitic fauna of domestic cats in eastern Brandenburg]. | The internal organs of 155 cats originating from 3 different territories in the eastern part of Brandenburg state were examined for parasites between 1993 and 1995. Parasites were found in 85% of cats. Parasites with the highest prevalence were Toxocara mystax (45%), Hydatigera taeniaeformis (22%), Ancylostoma tubaefor... | ['Animals', 'Animals, Domestic', 'Cat Diseases', 'Cats', 'Germany', 'Parasitic Diseases', 'Parasitic Diseases, Animal', 'Prevalence'] | 9,139,627 | [['B01.050'], ['B01.050.050.116'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['Z01.542.315'], ['C01.610'], ['C01.610.701', 'C22.674'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750']] | ['Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Inhibition of photosystem II by formate. Possible evidence for a direct role of bicarbonate in photosynthetic oxygen evolution. | In broken chloroplasts the presence of 100 mM sodium formate at pH 8.2 will specifically lengthen the Photosystem II relaxation times of the reactions S'2 leads to S3 and S'3 leads to S0. Rates of reactions S'0 leads to S1 and S'1 leads to S2 remain unaffected. Evidence is presented which indicates the discrimination a... | ['Bicarbonates', 'Chemical Phenomena', 'Chemistry', 'Formates', 'Oxygen', 'Photosynthesis', 'Plants'] | 7,426,637 | [['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['G02'], ['H01.181'], ['D02.241.081.420'], ['D01.268.185.550', 'D01.362.670'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G03.800.700', 'G15.568'], ['B01.650']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of a Zebrafish S1500+ Sentinel Gene Set for High-Throughput Transcriptomics. | Sentinel gene sets have been developed with the purpose of maximizing the information from targeted transcriptomic platforms. We recently described the development of an S1500+ sentinel gene set, which was built for the human transcriptome, utilizing a data- and knowledge-driven hybrid approach to select a small subset... | ['Animals', 'Computational Biology', 'Databases, Genetic', 'Gene Expression Profiling', 'High-Throughput Nucleotide Sequencing', 'Reproducibility of Results', 'Transcriptome', 'Zebrafish'] | 31,188,086 | [['B01.050'], ['H01.158.273.180', 'L01.313.124'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['E05.393.332'], ['E05.393.760.319'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['G02.111.873.750', 'G05.297.700.750', 'G05.360.920'], ['B01.050.150.900.493.200.244.828']... | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Overview of suspected adverse reactions to veterinary medicinal products reported in South Africa (March 2003 - February 2004). | The Veterinary Pharmacovigilance and Medicines Information Centre is responsible for the monitoring of veterinary adverse drug reactions in South Africa. An overview of reports of suspected adverse drug reactions received by the centre during the period March 2003 to February 2004 is given. A total of 20 reports was re... | ['Adverse Drug Reaction Reporting Systems', 'Animal Diseases', 'Animals', 'Animals, Domestic', 'Animals, Wild', 'South Africa', 'Veterinary Drugs'] | 15,906,455 | [['E05.337.800.120', 'N02.421.668.320.120'], ['C22'], ['B01.050'], ['B01.050.050.116'], ['B01.050.050.300'], ['Z01.058.290.175.735'], ['D26.939']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Ruptured intracranial aneurysms: factors affecting the rate and outcome of endovascular treatment complications in a series of 782 patients (CLARITY study). | PURPOSE: To analyze the clinical and anatomic factors that affect the occurrence and outcome of complications (thromboembolic events and intraoperative rupture) in the endovascular treatment of ruptured intracranial aneurysms in a large multicenter series, the CLARITY study (Clinical and Anatomic Results in the Treatme... | ['Adult', 'Aged', 'Aged, 80 and over', 'Aneurysm, Ruptured', 'Angioplasty, Balloon', 'Chi-Square Distribution', 'Embolization, Therapeutic', 'Female', 'France', 'Humans', 'Intracranial Aneurysm', 'Logistic Models', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prospective Studies', 'Risk Factors', 'Stents', 'T... | 20,720,074 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.055.185'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E02.520.360', 'E02.926.500'], ['Z01.542.286'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Endometrial injury for patients with endometriosis and polycystic ovary syndrome undergoing medically assisted reproduction: current data and a protocol. | We propose a study protocol capable of improving clinical outcomes following medically assisted reproduction (MAR) in infertile women with endometriosis and polycystic ovary syndrome (PCOS). The proposed research derives from the published evidence on the positive impact from endometrial injury (EI) and the beneficial ... | ['Adult', 'Endometriosis', 'Endometrium', 'Female', 'Humans', 'Infertility, Female', 'Ovulation Induction', 'Polycystic Ovary Syndrome', 'Pregnancy', 'Pregnancy Outcome', 'Prospective Studies', 'Reproductive Techniques, Assisted'] | 30,144,383 | [['M01.060.116'], ['C13.351.500.163'], ['A05.360.319.679.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['E02.875.800.984', 'E05.820.800.984'], ['C04.182.612.765', 'C13.351.500.056.630.580.765', 'C19.391.630.580.765'], ['G08.686.784.769'], ['E01.789.700', 'G08.686.784.769.496'], ['E05.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of exchange transfusion on elimination of antibiotics in premature infants. | Although the use of exchange transfusion has become routine in intensive care nurseries, little information is available on drug loss resulting from exchange transfusion. The aim of this study was to review the effect of exchange transfusion on the elimination of some antibiotics in premature infants according to the r... | ['Anti-Bacterial Agents', 'Exchange Transfusion, Whole Blood', 'Humans', 'Hyperbilirubinemia', 'Infant, Newborn', 'Infant, Premature'] | 8,191,611 | [['D27.505.954.122.085'], ['E02.095.135.469'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.429'], ['M01.060.703.520'], ['M01.060.703.520.520']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Innate immune response and disease resistance in Carassius auratus by triherbal solvent extracts. | This study reports the effect of aqueous, ethanol and methanol triherbal solvent extract from Azadirachta indica, Ocimum sanctum and Curcuma longa on innate immune mechanisms such as phagocytosis activity, respiratory burst activity, alternative complement activity and lysozyme activity and disease resistance in goldfi... | ['Aeromonas hydrophila', 'Animals', 'Azadirachta', 'Complement System Proteins', 'Curcuma', 'Fish Diseases', 'Goldfish', 'Gram-Negative Bacterial Infections', 'Immunity, Innate', 'Magnoliopsida', 'Muramidase', 'Ocimum', 'Phagocytosis', 'Plant Extracts', 'Respiratory Burst'] | 19,616,631 | [['B03.440.450.019.025.380'], ['B01.050'], ['B01.650.940.800.575.912.250.715.124'], ['D12.776.124.486.274'], ['B01.650.940.800.575.912.250.618.937.900.166'], ['C22.362'], ['B01.050.150.900.493.200.244.248.480'], ['C01.150.252.400'], ['G12.450.564'], ['B01.650.940.800.575.912.250'], ['D08.811.277.450.642'], ['B01.650.94... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Postprostatectomy target-normal structure overlap volume differences using computed tomography and radioimmunoscintigraphy images for radiotherapy treatment planning. | PURPOSE: The purpose of this study was to analyze regions of uptake in normal structures on postprostatectomy radioimmunoscintigraphy (RIS) images by evaluating differences in the overlap volumes of prostate fossa clinical target volume (CTV) and planning target volume (PTV) using correlative computed tomography (CT) i... | ['Humans', 'Male', 'Postoperative Care', 'Prostatectomy', 'Prostatic Neoplasms', 'Radiation Dosage', 'Radioimmunodetection', 'Radiometry', 'Radiotherapy Planning, Computer-Assisted', 'Retrospective Studies', 'Subtraction Technique', 'Tomography, X-Ray Computed'] | 16,495,731 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.731.700', 'E04.604.500', 'N02.421.585.722.700'], ['E04.950.774.860.625'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['E01.370.350.710.710', 'E01.370.384.730.710', 'E05.4... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Physical ill health, disability, dependence and depression: results from the 2007 national survey of psychiatric morbidity among adults in England. | BACKGROUND: The relationship between physical ill health, disability, and depression is not straightforward. Both cross-sectional and longitudinal studies have clearly shown that medical illness and physical disability are strongly associated with depression.OBJECTIVE: To test the hypothesis that disability is associat... | ['Activities of Daily Living', 'Adolescent', 'Adult', 'Aged', 'Depression', 'Depressive Disorder', 'Disability Evaluation', 'Disabled Persons', 'England', 'Female', 'Health', 'Health Status', 'Humans', 'Interviews as Topic', 'Male', 'Middle Aged', 'Prevalence', 'Severity of Illness Index', 'Young Adult'] | 22,429,544 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['F01.145.126.350'], ['F03.600.300'], ['E01.370.400'], ['M01.150'], ['Z01.542.363.300'], ['N01.400'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
[Retreatment after PRK for low and medium myopia. Results and study of contrast sensitivity]. | PURPOSE: To examine the results of retreatment with eximer laser photorefractive keratectomy (PRK) on refraction, visual acuity, haze, and contrast sensitivity.PATIENTS AND METHODS: Excimer laser photorefractive keratectomy was performed in 18 patients, once for one eye and twice for the other eye due to undercorrectio... | ['Adult', 'Contrast Sensitivity', 'Female', 'Humans', 'Lasers, Excimer', 'Male', 'Myopia', 'Photorefractive Keratectomy', 'Reoperation', 'Visual Acuity'] | 10,794,980 | [['M01.060.116'], ['E01.370.380.850.950.500', 'F02.463.593.778.435.110', 'F02.463.593.932.281', 'F02.463.593.932.901.500', 'G14.940.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.490.244', 'E07.710.520.244'], ['C11.744.636'], ['E02.594.480.875', 'E04.014.520.480.875', 'E04.378.500.875', 'E04.540.825.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Respiratory regulation in bronchial asthma]. | The aim of this study was to determine the changes in respiratory regulation in patients with bronchial asthma in different phases of the disease and after pharmacological bronchodilation. This study was carried out on 10 healthy volunteers and 35 asthmatics. In order to assess the changes in respiratory regulation the... | ['Adult', 'Asthma', 'Female', 'Humans', 'Hypercapnia', 'Male', 'Middle Aged', 'Respiration', 'Respiratory Function Tests'] | 2,631,048 | [['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.544'], ['M01.060.116.630'], ['G09.772.705'], ['E01.370.386.700']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Developmental programming of aortic and renal structure in offspring of rats fed fat-rich diets in pregnancy. | Evidence from human and animal studies suggests that maternal nutrition can induce developmental programming of adult hypertension in offspring. We have previously described a model of maternal dietary imbalance in Sprague-Dawley rats whereby administration of a maternal diet rich in animal lard programmes the developm... | ['Animal Nutritional Physiological Phenomena', 'Animals', 'Animals, Newborn', 'Aorta, Abdominal', 'Dietary Fats', 'Female', 'Kidney', 'Male', 'Maternal-Fetal Exchange', 'Nutritional Physiological Phenomena', 'Pregnancy', 'Pregnancy, Animal', 'Prenatal Exposure Delayed Effects', 'Prenatal Nutritional Physiological Pheno... | 15,774,514 | [['G07.203.650.161'], ['B01.050'], ['B01.050.050.282'], ['A07.015.114.056.205'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['A05.810.453'], ['G08.686.784.769.455'], ['G07.203.650'], ['G08.686.784.769'], ['G08.686.784.769.498'], ['C13.703.824.500'], ['G07.203.650.566.624', 'G08.686.784.769.600'], ['B01.050.150.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Impact of Excessive Weight Gain on Cardiovascular Outcomes in Type 1 Diabetes: Results From the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study. | OBJECTIVE: Intensive treatment (INT) of type 1 diabetes reduces the incidence of cardiovascular disease (CVD) events compared with conventional treatment (CONV), but it also results in more weight gain. Our objective was to examine whether excessive weight gain from INT of type 1 diabetes is independently associated wi... | ['Adult', 'Body Mass Index', 'Cardiovascular Diseases', 'Diabetes Mellitus, Type 1', 'Female', 'Follow-Up Studies', 'Humans', 'Hypoglycemic Agents', 'Incidence', 'Insulin', 'Male', 'Proportional Hazards Models', 'Risk Factors', 'Treatment Outcome', 'Weight Gain'] | 29,138,273 | [['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C14'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prediction of residual disease after primary cytoreductive surgery for advanced-stage ovarian cancer: accuracy of clinical judgment. | OBJECTIVES: Treatment of patients with an advanced-stage epithelial ovarian cancer (EOC) is based on cytoreductive surgery and platinum-based chemotherapy. Amount of residual disease after primary cytoreductive surgery is an important prognostic factor. The objectives of the present study were to evaluate the accuracy ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma', 'Clinical Competence', 'Decision Support Techniques', 'Disease Progression', 'Female', 'Gynecologic Surgical Procedures', 'Humans', 'Judgment', 'Middle Aged', 'Neoplasm Staging', 'Neoplasm, Residual', 'Observer Variation', 'Ovarian Neoplasms', 'Predictiv... | 19,955,927 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['E05.245', 'L01.313.500.750.190'], ['C23.550.291.656'], ['E04.950.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.785.626'], ['M01.060.116.630'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
A Super-Resolution Probe To Monitor HNO Levels in the Endoplasmic Reticulum of Cells. | Selective detection of nitroxyl (HNO), which has recently been identified as a reactive nitrogen species, is a challenging task. We report a BODIPY-based luminescence ON reagent for detection of HNO in aqueous solution and in live RAW 264.7 cells, based on the soft nucleophilicity of the phosphine oxide functionality t... | ['Animals', 'Artemia', 'Endoplasmic Reticulum', 'Fluorescent Dyes', 'Mice', 'Nitrogen Oxides', 'Optical Imaging', 'RAW 264.7 Cells'] | 29,069,900 | [['B01.050'], ['B01.050.500.131.365.060.050'], ['A11.284.430.214.190.875.248'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['D01.362.635', 'D01.625.550', 'D01.650.550.587'], ['E01.370.350.589', 'E05.642'], ['A11.251.210.172.875', 'A11.733.397.815']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cholesteatoma in children: histopathologic findings in middle ear ossicles. | Middle ear ossicles removed during ear surgery in 40 patients were examined in order to compare the histopathologic changes in children with those observed in adults. Bone resorption, mainly localized at the level of the periosteum and haversian canals in adults, was much more extensive in children. Replacement of bone... | ['Adolescent', 'Adult', 'Bone Resorption', 'Child', 'Cholesteatoma, Middle Ear', 'Chronic Disease', 'Disease Progression', 'Ear Ossicles', 'Granulation Tissue', 'Granulocytes', 'Haversian System', 'Humans', 'Lymphocytes', 'Macrophages', 'Mast Cells', 'Osteitis', 'Osteoclasts', 'Otitis Media', 'Periosteum', 'Plasma Cell... | 8,587,786 | [['M01.060.057'], ['M01.060.116'], ['C05.116.264', 'G11.427.213.150'], ['M01.060.406'], ['C09.218.200', 'C17.800.428.260.300'], ['C23.550.291.500'], ['C23.550.291.656'], ['A09.246.397.247'], ['A10.165.450'], ['A11.118.637.415', 'A11.148.350', 'A11.627.340', 'A15.145.229.637.415', 'A15.378.316.340', 'A15.382.490.315'], ... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The association between IGF-I/IGFBP-3 and subclinical end points: epidemiology faces the limits. | BACKGROUND: The variation in laboratory measurements represents a challenge in clinical practice and epidemiological research. The use of different analytical platforms might have led to different results, which were often discussed in the interpretation of conflicting results. We aim to study the impact of two differe... | ['Adult', 'Aged', 'Asymptomatic Diseases', 'Cardiovascular Diseases', 'Endpoint Determination', 'Epidemiologic Research Design', 'Female', 'Genome-Wide Association Study', 'Humans', 'Immunoassay', 'Insulin-Like Growth Factor Binding Protein 3', 'Insulin-Like Growth Factor I', 'Male', 'Middle Aged', 'Polymorphism, Singl... | 24,823,454 | [['M01.060.116'], ['M01.060.116.100'], ['C23.550.291.187'], ['C14'], ['E05.315'], ['E05.318.370', 'N05.715.360.325', 'N06.850.520.445'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['B01.050.150.900.649.313.988.400.11... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Postmastectomy breast reconstruction in Connecticut: trends and predictors. | Using the population-based Connecticut Tumor Registry, postmastectomy breast reconstruction was examined in the 10,756 breast cancers in Connecticut women (including 10,133 in white women and 554 in black women) diagnosed from 1988 to 1995. Reconstruction increased from 6.4 percent of cancers in 1988 to 9.1 percent in ... | ['Adult', 'African Americans', 'Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Connecticut', 'Female', 'Humans', 'Logistic Models', 'Mammaplasty', 'Mastectomy', 'Middle Aged', 'Odds Ratio', 'Poverty'] | 10,456,516 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['Z01.107.567.875.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Statistical controversies in clinical research: scientific and ethical problems with adaptive randomization in comparative clinical trials. | BACKGROUND: In recent years, various outcome adaptive randomization (AR) methods have been used to conduct comparative clinical trials. Rather than randomizing patients equally between treatments, outcome AR uses the accumulating data to unbalance the randomization probabilities in favor of the treatment arm that curre... | ['Bayes Theorem', 'Bias', 'Computer Simulation', 'Humans', 'Random Allocation', 'Randomized Controlled Trials as Topic', 'Statistics as Topic'] | 25,979,922 | [['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['N05.715.350.150', 'N06.850.490.500'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['E05.318.372.250.250.365.500', 'N05.715.360.330... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Autologous platelet concentrate for the treatment of full-thickness macular holes. | BACKGROUND: To improve the anatomic success rate in the surgery of full-thickness macular holes, we tested, in a prospective pilot study, the effects of autologous platelet concentrate deposited on the macula at the end of surgery.METHODS: Two consecutive groups of patients were compared. Twenty eyes (group 1, mean sym... | ['Adult', 'Aged', 'Blood Platelets', 'Fluorescein Angiography', 'Fundus Oculi', 'Humans', 'Injections', 'Middle Aged', 'Pilot Projects', 'Prognosis', 'Prospective Studies', 'Retinal Perforations', 'Visual Acuity', 'Vitrectomy'] | 8,543,204 | [['M01.060.116'], ['M01.060.116.100'], ['A11.118.188', 'A15.145.229.188'], ['E01.370.370.050.350', 'E01.370.380.250'], ['A09.371.729.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530'], ['M01.060.116.630'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E01.7... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Phosphorylation of the adenovirus DNA-binding protein and epitope mapping of monoclonal antibodies against it. | To facilitate structure/function studies of the adenovirus type 2 or 5 single-stranded DNA binding protein (DBP), the epitopes of five anti-DBP monoclonal antibodies were mapped. Antibodies 37-3, 38-2, and B6 mapped between DBP residues 131-174 which corresponds to the host-range or hinge region of the molecule. The ep... | ['Adenovirus E2 Proteins', 'Adenoviruses, Human', 'Animals', 'Antibodies, Monoclonal', 'Antibodies, Viral', 'Antibody Specificity', 'Cells, Cultured', 'DNA-Binding Proteins', 'Epitopes', 'Haplorhini', 'Humans', 'Phosphorylation', 'Phosphoserine', 'Serine'] | 7,504,365 | [['D12.776.260.060', 'D12.776.624.664.520.045.060', 'D12.776.964.700.045.060', 'D23.050.327.045.060'], ['B04.280.030.500.350'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cerebral blood flow in chronic cocaine users: a study with positron emission tomography. | Occurrence of cerebrovascular accidents has been associated with cocaine abuse. We investigated the relative distribution of cerebral blood flow (CBF) in groups of chronic cocaine users, and of normal controls. Relative CBF was measured using positron emission tomography and 15 oxygen-labelled water. The cocaine users ... | ['Adult', 'Brain', 'Cerebrovascular Circulation', 'Cocaine', 'Frontal Lobe', 'Humans', 'Male', 'Substance-Related Disorders', 'Tomography, Emission-Computed'] | 3,262,397 | [['M01.060.116'], ['A08.186.211'], ['G09.330.100.159'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C25.775', 'F03.900'], ['E01.370.350.350.800', 'E01.370.350.600.350.800', 'E01.370.350.... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reward-priming of location in visual search. | Existing visual search research has demonstrated that the receipt of reward will be beneficial for subsequent perceptual and attentional processing of features that have characterized targets, but detrimental for processing of features that have characterized irrelevant distractors. Here we report a similar effect of r... | ['Humans', 'Reward', 'Vision, Ocular'] | 25,080,218 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.770.836'], ['F02.830.816.964', 'G02.111.820.480.900', 'G04.835.480.900', 'G11.561.790.964', 'G14.935']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characteristics of residents who thrive in nursing home environments: a cross-sectional study. | AIM: To describe what characterizes residents with higher levels compared with those with lower levels of thriving in nursing homes using the Thriving of Older People Assessment Scale.BACKGROUND: Thriving is conceptualized as people's experiences of well-being in relation to the environment where they live. Thriving ha... | ['Activities of Daily Living', 'Aged', 'Cross-Sectional Studies', 'Female', 'Humans', 'Length of Stay', 'Male', 'Nursing Homes', 'Quality of Life', 'Sweden'] | 27,144,469 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['N02.278.825.610'], ['I01.800', 'K01.752.400.750', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Biofunctionalization of polyelectrolyte microcapsules with biotinylated polyethylene glycol-grafted liposomes. | Hollow polyelectrolyte microcapsules (PEMC) are prepared using layer-by-layer self-assembly of polyelectrolytes on melamine formaldehyde templates, followed by template dissolution, and subsequent coating with biotinylated polyethylene glycol-grafted liposomes. These potential site-specific carrier systems show a high ... | ['Artificial Cells', 'Avidin', 'Biocompatible Materials', 'Biomimetics', 'Biotin', 'Biotinylation', 'Capsules', 'Drug Carriers', 'Electrolytes', 'Flow Cytometry', 'Humans', 'Liposomes', 'Microscopy, Atomic Force', 'Microscopy, Fluorescence', 'Polyethylene Glycols', 'Triazines'] | 21,557,479 | [['J01.637.051.479.258', 'J01.637.087.500.254'], ['D12.776.034.614.300', 'D12.776.256.159.157.663.300', 'D12.776.290.663.100', 'D12.776.395.175'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['H01.158.550.100', 'J01.897.120.100'], ['D03.383.129.308.080', 'D08.211.096'], ['E05.601.085', 'G02.111.109', 'G03.162'],... | ['Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Postconcussional disorder: Are the DSM-IV criteria an improvement over the ICD-10? | Little is known about the characteristics and outcomes of patients diagnosed with postconcussional disorder (PCD) under the provisionally proposed criteria in the DSM-IV and how they differ from patients diagnosed with postconcussional syndrome (PCS) under the International Classification of Diseases, 10th edition clin... | ['Adult', 'Anxiety Disorders', 'Brain Injuries', 'Depressive Disorder', 'Diagnostic and Statistical Manual of Mental Disorders', 'Female', 'Follow-Up Studies', 'Health Status', 'Humans', 'International Classification of Diseases', 'Male', 'Neuropsychological Tests', 'Outcome Assessment, Health Care', 'Post-Concussion S... | 16,082,299 | [['M01.060.116'], ['F03.080'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['F03.600.300'], ['L01.453.245.945.200'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Humanities [K]'... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Evaluation of anesthesia in endoscopic strip craniectomy: A review of 121 patients. | OBJECTIVE: The aim of this study was to evaluate pre-, intra-, and postoperative anesthetic parameters in endoscopic strip craniectomy in order to improve anesthesiological care.MATERIALS AND METHODS: This is a retrospective patient cohort study of our first 121 patients treated by endoscopic strip craniectomy. Preoper... | ['Anesthetics, Inhalation', 'Blood Loss, Surgical', 'Cohort Studies', 'Craniosynostoses', 'Craniotomy', 'Endoscopy', 'Humans', 'Hypothermia', 'Infant', 'Intraoperative Complications', 'Oxygen', 'Postoperative Complications', 'Retrospective Studies', 'Sevoflurane', 'Treatment Outcome'] | 29,851,178 | [['D27.505.696.277.100.035.060', 'D27.505.954.427.210.100.035.060'], ['C23.550.414.300', 'C23.550.505.300'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C05.116.099.370.894.232', 'C05.660.207.240', 'C05.660.906.364', 'C16.131.621.207.240', 'C16.131.621.906.364'], ['E04.525.190'], ['... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Isolated ACL versus multiple knee ligament injury: associations with patient characteristics, cartilage status, and meniscal tears identified during ACL reconstruction. | OBJECTIVES: The objectives of this study were to determine (1) if patients undergoing reconstruction of an isolated anterior cruciate ligament (ACL) tear had different characteristics (age, gender, body mass index [BMI]) than patients undergoing ACL reconstruction (ACLR) with multiple knee ligament (MKL) tears and (2) ... | ['Adolescent', 'Adult', 'Age Factors', 'Anterior Cruciate Ligament Injuries', 'Anterior Cruciate Ligament Reconstruction', 'Body Mass Index', 'California', 'Cohort Studies', 'Comorbidity', 'Female', 'Femur', 'Humans', 'Ligaments, Articular', 'Male', 'Prevalence', 'Probability', 'Registries', 'Risk Factors', 'Rupture', ... | 28,425,824 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['C26.558.554.213'], ['E04.555.110.026', 'E04.680.101.026'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['E05.318.372.500.750', 'N05.715.3... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mothers' attachment security predicts their children's sense of God's closeness. | The current research reports that mothers' security of attachment predicts their children's sense of God's closeness. A total of 71 mother-child dyads participated (children's M age = 7.5). Mothers' attachment organization was studied with the Adult Attachment Interview (AAI; Main, Goldwyn, & Hesse, 2003 ) and their re... | ['Child', 'Child Rearing', 'Child, Preschool', 'Female', 'Humans', 'Internal-External Control', 'Male', 'Mother-Child Relations', 'Mothers', 'Object Attachment', 'Psychometrics', 'Qualitative Research', 'Spirituality', 'Surveys and Questionnaires'] | 23,216,392 | [['M01.060.406'], ['F01.318'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['F01.829.263.370.290.170'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M01.620.630'], ['F02.739.794.624'], ['F04.711.780'], ['H01.770.644.241.850'], ['F02.880.705', 'K01.844.664.500'],... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
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