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Biochemical studies on rat liver Golgi apparatus. IV. Effects of various treatments in vivo on the Golgi apparatus. | The effects of various treatments in vivo on the intracellular contents of the Golgi apparatus and microsomes (endoplasmic reticulum) in rat liver were studied. Partial hepatectomy increased the content of Golgi apparatus. Laparotmy also increased the content of Golgi apparatus, but to a lesser extent than partial hepa... | ['Animals', 'Galactosyltransferases', 'Golgi Apparatus', 'Laparotomy', 'Liver', 'Liver Regeneration', 'Male', 'Microsomes, Liver', 'Papain', 'Phenobarbital', 'Proteins', 'Rats'] | 739,003 | [['B01.050'], ['D08.811.913.400.450.400'], ['A11.284.430.214.190.875.336'], ['E04.406'], ['A03.620'], ['G10.261.475', 'G16.762.468'], ['A11.284.835.540.541'], ['D08.811.277.656.262.500.585', 'D08.811.277.656.300.200.585'], ['D03.383.742.698.253.650'], ['D12.776'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prenatal sonographic findings associated with malignant astrocytoma following normal early third-trimester ultrasonography. | We present an unusual case in which sonographic assessment at 33 weeks' gestation, 5 weeks following a normal fetal anatomical survey and biometry, demonstrated a large, irregular-shaped, echogenic, suprasellar midline intracranial mass occupying the anterior and middle fossas. Associated severe obstructive hydrocephal... | ['Adult', 'Brain Neoplasms', 'Cesarean Section', 'Female', 'Gestational Age', 'Glioblastoma', 'Humans', 'Hydrocephalus', 'Infant, Newborn', 'Male', 'Pregnancy', 'Pregnancy Trimester, Third', 'Ultrasonography, Prenatal', 'Ventriculoperitoneal Shunt'] | 9,926,880 | [['M01.060.116'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E04.520.252.500'], ['G07.345.500.325.235.968', 'G08.686.320'], ['C04.557.465.625.600.380.080.335', 'C04.557.470.670.380.080.335', 'C04.557.580.625.600.380.080.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.602'], [... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of homocysteine on cytokine production by human endothelial cells and monocytes. | BACKGROUND: Hyperhomocysteinaemia is an independent risk factor in the development of cardiovascular disease. Although homocysteine has been shown to affect endothelial cell function, the mechanisms by which it induces disease states are still poorly understood. Here, we report the ability of homocysteine to influence ... | ['Cell Size', 'Cells, Cultured', 'Cytokines', 'Endothelial Cells', 'Homocystine', 'Humans', 'Macrophages', 'Monocytes', 'Veins'] | 14,503,991 | [['G04.325'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A11.436.275'], ['D02.886.030.554', 'D12.125.095.533', 'D12.125.119.658', 'D12.125.166.554'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['A11.118... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The presence of free G protein beta/gamma subunits in human neutrophils results in suppression of adenylate cyclase activity. | We have examined the adenylate cyclase of human neutrophil membranes and compared it to that of human platelet membranes. Stimulated activities were at least 20-fold lower in the neutrophil than in the human platelet. The inhibitory hormone epinephrine was able to attenuate markedly the adenylate cyclase activity of hu... | ['Adenylyl Cyclase Inhibitors', 'Adenylyl Cyclases', 'Animals', 'Blood Platelets', 'Cattle', 'Cell Membrane', 'Epinephrine', 'GTP-Binding Proteins', "Guanosine 5'-O-(3-Thiotriphosphate)", 'Guanosine Triphosphate', 'Humans', 'Macromolecular Substances', 'Neutrophils', 'Thionucleotides'] | 3,100,516 | [['D27.505.519.389.108'], ['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['B01.050'], ['A11.118.188', 'A15.145.229.188'], ['B01.050.150.900.649.313.500.380.271'], ['A11.284.149'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.46... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protein C inhibitor directly and potently inhibits activated hepatocyte growth factor activator. | BACKGROUND: Hepatocyte growth factor (HGF) plays an important role in tissue repair and regeneration. HGF activator (HGFA), a factor XIIa-like serine protease, activates HGF precursor to HGF. The precursor of HGFA, proHGFA, is activated by thrombin generated at sites of tissue injury. It is known that protein C inhibit... | ['Adult', 'Base Sequence', 'DNA, Complementary', 'Hepatocyte Growth Factor', 'Humans', 'In Vitro Techniques', 'Macromolecular Substances', 'Middle Aged', 'Models, Molecular', 'Protein C', 'Protein C Inhibitor', 'Protein Precursors', 'Recombinant Proteins', 'Serine Endopeptidases', 'Thrombin', 'Thrombomodulin'] | 17,456,194 | [['M01.060.116'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D12.644.276.374.420', 'D12.776.467.374.420', 'D23.529.374.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D05'], ['M01.060.116.630'], ['E05... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Optical fiber axial micro-displacement sensor based on Mach-Zehnder interferometer. | A Mach-Zehnder interferometer (MZI) based fiber axial micro-displacement sensor was proposed. The MZI was constructed by a bowknot-type taper (BTT) combining with a fiber core-offset between two single mode fibers (SMFs). The axial micro-displacement of the core offset is correlated with the MZI transmission spectrum a... | ['Computer Simulation', 'Computer-Aided Design', 'Equipment Design', 'Equipment Failure Analysis', 'Fiber Optic Technology', 'Interferometry', 'Models, Theoretical', 'Motion', 'Optical Devices', 'Refractometry', 'Torque', 'Transducers', 'Transducers, Pressure'] | 25,607,166 | [['L01.224.160'], ['L01.224.108.150', 'L01.296.110.150'], ['E05.320'], ['E05.325.192'], ['H01.671.617.249'], ['E05.490'], ['E05.599'], ['G01.482'], ['E07.632'], ['E05.196.808', 'H01.671.617.755'], ['G01.374.860.500'], ['E07.305.812'], ['E07.305.812.901']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Drug eruptions from mesna. After cyclophosphamide treatment of patients with systemic lupus erythematosus and dermatomyositis. | BACKGROUND: Mesna is used to abolish urotoxicity of cyclophosphamide and related compounds in immunosuppressive and antineoplastic treatment schedules. Adverse reactions to this drug have been reported only rarely.OBSERVATIONS: Drug eruptions to mesna have developed in seven of 15 patients with autoimmune disorders tre... | ['Adult', 'Biopsy', 'Cyclophosphamide', 'Dermatomyositis', 'Drug Eruptions', 'Drug Therapy, Combination', 'Female', 'Humans', 'Lupus Erythematosus, Systemic', 'Male', 'Mesna', 'Methylprednisolone', 'Metoclopramide', 'Middle Aged', 'Patch Tests', 'Skin'] | 1,531,405 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['C05.651.594.819.500', 'C10.668.491.562.575.500', 'C17.300.250', 'C17.800.185'], ['C17.800.174.600', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Anti-inflammatory and antioxidant effect of ginger in tuberculosis. | BACKGROUND: Tuberculosis (TB) has reemerged to become the world's leading cause of death from a single infectious agent. Inflammatory cytokines play an important role during the course of the disease and may be responsible for tissue damage by lipid peroxidation. The study was aimed to explore the anti-inflammatory and... | ['Adolescent', 'Adult', 'Anti-Inflammatory Agents', 'Antioxidants', 'Antitubercular Agents', 'Dietary Supplements', 'Drug Therapy, Combination', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Ferritins', 'Ginger', 'Humans', 'Inflammation Mediators', 'Male', 'Malondialdehyde', 'Middle Aged', 'Oxidative Stress', 'Phytot... | 27,089,418 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.158'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D27.505.954.122.085.255'], ['G07.203.300.456', 'J02.500.456'], ['E02.319.310'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Discourse representation in the two cerebral hemispheres. | Readers construct at least two interrelated representations when they comprehend a text: (a) a propositional representation containing the individual ideas that are derived from each sentence and the relations among them and (b) a discourse model, a representation of the context or situation to which the text refers. W... | ['Adult', 'Cerebral Cortex', 'Corpus Callosum', 'Dominance, Cerebral', 'Epilepsy', 'Female', 'Humans', 'Male', 'Memory', 'Pattern Recognition, Visual', 'Reading', 'Visual Fields'] | 11,970,788 | [['M01.060.116'], ['A08.186.211.200.885.287.500'], ['A08.186.211.200.885.800.750'], ['F02.830.297', 'G11.561.225'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['L01.559.423.557'], ['F02.463.593.932.934', 'G14.950']] | ['Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Surgeon beware: many patients referred for parathyroidectomy are misdiagnosed with primary hyperparathyroidism. | PURPOSE: We hypothesized that patients referred for the evaluation and management of primary hyperparathyroidism (pHPT) often do not have pHPT and that they may be harmed by unwarranted parathyroidectomy (PTX).METHODS: We reviewed all patients who were referred to our endocrine surgery practice between 2008 and 2011 wi... | ['Diagnosis, Differential', 'Diagnostic Errors', 'Humans', 'Hypercalcemia', 'Hyperparathyroidism, Primary', 'Hyperparathyroidism, Secondary', 'Parathyroid Neoplasms', 'Parathyroidectomy', 'Referral and Consultation', 'Retrospective Studies'] | 23,021,135 | [['E01.171'], ['E01.354', 'N02.421.450.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.174.451', 'C18.452.950.340'], ['C19.642.355.239'], ['C19.642.355.480'], ['C04.588.322.525', 'C04.588.443.680', 'C19.344.525', 'C19.642.713'], ['E04.270.694'], ['N04.452.758.849'], ['E05.318.372.500.500.500', 'E05.31... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Enhanced DNA binding of 9-ù-amino alkyl ether analogs from the plant alkaloid berberine. | To understand the structure-activity relationship of isoquinoline alkaloids, absorption, fluorescence, circular dichroism, and thermodynamics were employed to study the interaction of five C-9-ù-amino alkyl ether analogs from the plant alkaloid berberine with double-stranded calf thymus DNA. The C-9 derivatization resu... | ['Absorption', 'Animals', 'Berberine', 'Calorimetry', 'Cattle', 'Circular Dichroism', 'DNA', 'Ethers', 'Ethidium', 'Nucleic Acid Denaturation', 'Plants', 'Spectrometry, Fluorescence', 'Structure-Activity Relationship', 'Transition Temperature'] | 20,929,398 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['B01.050'], ['D03.132.098.057.100', 'D03.633.400.168.100'], ['E05.196.131'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.867.151'], ['D13.444.308'], ['D02.355'], ['D03.633.300.633.416'], ['E05.393.640', 'G02.111.603', 'G05.627'], ['B01.650'],... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ultrastructural alterations in rabbit taste buds induced by prolonged treatment with cycloheximide. | Prolonged administration of cycloheximide, an inhibitor of ribosomal protein synthesis, induces degeneration of rabbit taste bud cells: the degenerative changes resemble early changes in denervated taste buds. Our observations show that the pattern of degeneration is quite different in the three cell types of the taste... | ['Animals', 'Cell Nucleolus', 'Cycloheximide', 'Cytoplasm', 'Endoplasmic Reticulum', 'Golgi Apparatus', 'Rabbits', 'Taste Buds'] | 1,200,785 | [['B01.050'], ['A11.284.430.106.279.345.175'], ['D03.383.621.808.240'], ['A11.284.430.214'], ['A11.284.430.214.190.875.248'], ['A11.284.430.214.190.875.336'], ['B01.050.150.900.649.313.968.700'], ['A03.556.500.885.779', 'A08.675.650.915.500.800', 'A08.800.950.500.800', 'A09.846', 'A11.671.650.915.500.800', 'A14.549.885... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Androgen exposure and reproductive behavior of an induced ovulator, the pine vole (Microtus pinetorum). | The actions of steroid hormones on brain and behavior are classically divided into organizational effects that are permanent and occur early in development and activational effects that are temporary and occur throughout life. Here, we test the hypothesis that in an induced ovulator, testosterone defeminizes only those... | ['Androgens', 'Animals', 'Arvicolinae', 'Female', 'Male', 'Sexual Behavior, Animal', 'Uterus'] | 9,047,267 | [['D27.505.696.399.472.161'], ['B01.050'], ['B01.050.150.900.649.313.992.635.075'], ['F01.145.113.252.748'], ['A05.360.319.679']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Predictors of Ibandronate Efficacy for the Management of Osteoporosis: A Meta-Regression Analysis. | BACKGROUND: Aim of the present study was to identify the predictors of ibandronate efficacy in subjects with osteoporosis or decreased bone mineral density (BMD).METHOD: Several electronic databases were searched by using specific keywords for the acquisition of research articles reporting the efficacy of ibandronate i... | ['Bone Density', 'Bone Density Conservation Agents', 'Diphosphonates', 'Humans', 'Ibandronic Acid', 'Osteoporosis', 'Regression Analysis', 'Treatment Outcome'] | 26,930,292 | [['G11.427.100'], ['D27.505.696.242'], ['D02.705.429.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.705.429.500.844'], ['C05.116.198.579', 'C18.452.104.579'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Suture Repair of a Pole Patella Fracture. | PURPOSE: Operative fixation of displaced patella fractures is considered to be standard of care. However, patients with inferior pole patella fractures have limited options in terms of fixation. This video demonstrates the repair of an inferior pole patella fracture using nonabsorbable suture fixation.METHODS: Suture r... | ['Accidental Falls', 'Aged', 'Bone Wires', 'Female', 'Follow-Up Studies', 'Fracture Fixation, Internal', 'Fracture Healing', 'Humans', 'Injury Severity Score', 'Patella', 'Patellar Dislocation', 'Patient Positioning', 'Recovery of Function', 'Risk Assessment', 'Suture Techniques', 'Treatment Outcome', 'Video Recording'... | 28,697,081 | [['N06.850.135.122'], ['M01.060.116.100'], ['E07.695.370.468', 'E07.858.442.660.460.468', 'E07.858.690.725.460.468'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.555.300.300'], ['G16.762.891.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.940.96... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Improving cancer classification accuracy using gene pairs. | Recent studies suggest that the deregulation of pathways, rather than individual genes, may be critical in triggering carcinogenesis. The pathway deregulation is often caused by the simultaneous deregulation of more than one gene in the pathway. This suggests that robust gene pair combinations may exploit the underlyin... | ['Algorithms', 'Bayes Theorem', 'Biomarkers, Tumor', 'Computational Biology', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Models, Biological', 'Models, Genetic', 'Models, Statistical', 'Neoplasms', 'Oligonucleotide Array Sequence Analysis', 'Reproducibility of Results', 'Sequence Analysis, DNA'] | 21,200,431 | [['G17.035', 'L01.224.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['D23.101.140'], ['H01.158.273.180', 'L01.313.124'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['E05.599.395.397'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
The Pathophysiology of Uric Acid on Renal Diseases. | BACKGROUND: Asymptomatic hyperuricemia was regarded as a marker and considered secondary to some pathological conditions such as hypertension. During the last 16 years, a vast amount of experimental work has shown that uric acid can cause intracellular alterations that lead to cardiovascular, renal, and metabolic disea... | ['Animals', 'Disease Models, Animal', 'Hemodynamics', 'Humans', 'Hypertension', 'Hyperuricemia', 'Kidney Diseases', 'Oxidative Stress', 'Renal Circulation', 'Uric Acid'] | 29,393,088 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C23.550.449'], ['C12.777.419', 'C13.351.968.419'], ['G03.673', 'G07.775.750'], ['G08.852.725', 'G09.330.100.812'], ['D03.132.960.877', 'D03.633.100.759.758.824.877']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular identification of algal endosymbionts in large miliolid foraminifera: 1. Chlorophytes. | Large miliolid foraminifers bear various types of algal endosymbionts including chlorophytes, dinoflagellates, rhodophytes, and diatoms. Symbiosis plays a key role in the adaptation of large foraminifera to survival and growth in oligotrophic seas. The identity and diversity of foraminiferal symbionts, however, remain ... | ['Animals', 'Base Sequence', 'Chlamydomonas', 'Chlorophyta', 'DNA, Protozoan', 'DNA, Ribosomal Spacer', 'Eukaryota', 'Molecular Sequence Data', 'Phylogeny', 'Sequence Homology, Nucleic Acid', 'Symbiosis'] | 11,411,845 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.650.940.150.385'], ['B01.650.940.150'], ['D13.444.308.442'], ['D13.444.308.324.230', 'D13.444.308.475.230'], ['B01'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G02.111.810.550', 'G05.810.550'], ['G06.550.800', 'G16.84... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Face recognition using recursive Fisher linear discriminant. | Fisher linear discriminant (FLD) has recently emerged as a more efficient approach for extracting features for many pattern classification problems as compared to traditional principal component analysis. However, the constraint on the total number of features available from FLD has seriously limited its application to... | ['Algorithms', 'Artificial Intelligence', 'Computer Simulation', 'Databases, Factual', 'Discriminant Analysis', 'Face', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Information Storage and Retrieval', 'Linear Models', 'Models, Anatomic', 'Pattern Recognition, Automated', 'Reproducibility o... | 16,900,667 | [['G17.035', 'L01.224.050'], ['G17.035.250', 'L01.224.050.375'], ['L01.224.160'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E05.318.740.350', 'N05.715.360.750.325', 'N06.850.520.830.350'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Informed-Proteomics: open-source software package for top-down proteomics. | Top-down proteomics, the analysis of intact proteins in their endogenous form, preserves valuable information about post-translation modifications, isoforms and proteolytic processing. The quality of top-down liquid chromatography-tandem MS (LC-MS/MS) data sets is rapidly increasing on account of advances in instrument... | ['Algorithms', 'Chromatography, High Pressure Liquid', 'Programming Languages', 'Proteome', 'Proteomics', 'Software', 'Systems Integration', 'Tandem Mass Spectrometry', 'User-Computer Interface'] | 28,783,154 | [['G17.035', 'L01.224.050'], ['E05.196.181.400.300'], ['L01.224.900.780'], ['D12.776.817'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.738'], ['L01.224.900'], ['H01.770.787', 'L01.906.787'], ['E05.196.566.880'], ['L01.224.900.910']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Comparisons of molecular karyotype and RAPD patterns of anuran trypanosome isolates during long-term in vitro cultivation. | The patterns of random amplified fragments and molecular karyotypes of 12 isolates of anuran trypanosomes continuously cultured in vitro were compared by random amplified polymorphic DNA (RAPD) analysis and pulsed field gradient gel electrophoresis (PFGE). The time interval between preparation of two series of samples ... | ['Animals', 'Anura', 'DNA, Protozoan', 'Electrophoresis, Gel, Pulsed-Field', 'Karyotyping', 'Random Amplified Polymorphic DNA Technique', 'Trypanosoma'] | 9,061,897 | [['B01.050'], ['B01.050.150.900.090.180'], ['D13.444.308.442'], ['E05.196.401.220', 'E05.301.300.220'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['E05.393.620.500.687', 'E05.601.700'], ['B01.268.475.868.887']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Grant writing tips for translational research. | All investigators face the same challenge - the highly competitive nature of the grant review process. Innovation alone is not enough to ensure grant supported funding. Applied clinical research requires a diverse collaborative team of investigators with specialized skills, a supportive clinical research environment, a... | ['Humans', 'Research Support as Topic', 'Translational Medical Research', 'Writing'] | 22,081,359 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.483.645'], ['H01.770.644.145.675'], ['L01.559.423.906']] | ['Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Accuracy of four-dimensional phase-contrast velocity mapping for blood flow visualizations: a phantom study. | BACKGROUND: Time-resolved three-dimensional, three-directional phase-contrast magnetic resonance velocity mapping (4D PC-MRI) is a powerful technique to depict dynamic blood flow patterns in the human body. However, the impact of phase background effects on flow visualizations has not been thoroughly studied previously... | ['Blood Flow Velocity', 'Equipment Design', 'Humans', 'Magnetic Resonance Angiography', 'Phantoms, Imaging'] | 23,486,562 | [['E01.370.370.130', 'G09.330.380.630.080'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500.500', 'E01.370.370.050.500'], ['E07.671']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Age, marital satisfaction, and optimism as predictors of positive sentiment override in middle-aged and older married couples. | This study examined whether positive sentiment override (greater positive appraisal of spouse's affiliative behavior than is warranted by observed behavior) occurred more frequently in older compared with middle-aged married couples and whether age differences were mediated by older adults' greater marital satisfaction... | ['Adult', 'Affect', 'Age Factors', 'Aged', 'Aging', 'Attitude', 'Female', 'Humans', 'Male', 'Marriage', 'Middle Aged', 'Personal Satisfaction', 'Prospective Studies', 'Social Behavior'] | 18,179,292 | [['M01.060.116'], ['F01.470.047'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['G07.345.124'], ['F01.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.315.500.500', 'I01.240.361.500.500', 'I01.880.853.150.423.500.500', 'N01.224.361.500.500', 'N01.824.308.500.500'], ['M01.060.116.63... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A Recurrent Case of Ischemic Stroke Caused by Vasospasm due to Giant Cell Arteritis. | A 73-year-old man was admitted with sudden right upper-limb weakness. He had a temporal headache on the left side and had a 4-month history of fever. Meandering of the left temporal artery (TA) with induration and high inflammatory responses (white blood cell count 22,500 per microliter, C-reactive protein 35.0 mg/dL, ... | ['Aged', 'Brain Ischemia', 'C-Reactive Protein', 'Giant Cell Arteritis', 'Humans', 'Magnetic Resonance Angiography', 'Magnetic Resonance Imaging', 'Male', 'Stroke', 'Vasospasm, Intracranial'] | 28,843,802 | [['M01.060.116.100'], ['C10.228.140.300.150', 'C14.907.253.092'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['C10.114.875.700', 'C10.228.140.300.850.500', 'C14.907.253.946.700', 'C14.907.940.090.530', 'C14.907.940.907.700', 'C17.800.862.252', 'C20.111.258.962.800'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Grain-based activated carbons for natural gas storage. | Natural gas has emerged as a potential alternative to gasoline due to the increase in global energy demand and environmental concerns. An investigation was undertaken to explore the technical feasibility of implementing the adsorbed natural gas (ANG) storage in the fuel tanks of motor vehicles with activated carbons fr... | ['Adsorption', 'Biomass', 'Biotechnology', 'Carbon', 'Charcoal', 'Conservation of Energy Resources', 'Edible Grain', 'Equipment Design', 'Fossil Fuels', 'Methane', 'Nitrogen', 'Porosity', 'Pressure', 'Sorghum', 'Triticum'] | 19,945,864 | [['G01.030', 'G02.020'], ['G16.500.275.157.100', 'N06.230.124.100'], ['H01.158.550', 'J01.897.120'], ['D01.268.150'], ['D01.268.150.150'], ['N06.230.080.078'], ['A18.024.500.750.500', 'B01.650.160.250', 'B01.650.510.250', 'G07.203.300.300.550', 'G07.203.300.775.500', 'J02.500.300.550', 'J02.500.775.500'], ['E05.320'], ... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Effects of isoxuprine and nylidrin on adrenoreceptors in rat vas deferens. | The interaction of isoxuprine and nylidrin with alpha 1- and beta 2-adrenoreceptors in rat vas deferens was examined using radioligand binding assays and physiological studies in vitro. Isoxuprine and nylidrin have a greater affinity for binding to alpha 1 (isoxuprine KD = 59 +/- 15 nM; nylidrin KD = 41 +/- 3 nM) than ... | ['Animals', 'Binding, Competitive', 'In Vitro Techniques', 'Isoxsuprine', 'Male', 'Muscle Contraction', 'Muscle Relaxation', 'Muscle, Smooth', 'Nylidrin', 'Rats', 'Rats, Inbred Strains', 'Receptors, Adrenergic', 'Receptors, Adrenergic, alpha', 'Receptors, Adrenergic, beta', 'Reserpine', 'Vas Deferens'] | 2,997,229 | [['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['E05.481'], ['D02.033.100.624.427', 'D02.033.755.624.427', 'D02.092.471.683.560'], ['G11.427.494'], ['G11.427.494.554'], ['A02.633.570', 'A10.690.467'], ['D02.033.100.624.605', 'D02.033.755.624.605', 'D02.092.063.624.706.550', 'D02.092.471.683.715'],... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. | The chromosomal passenger complex of Aurora B kinase, INCENP, and Survivin has essential regulatory roles at centromeres and the central spindle in mitosis. Here, we describe Borealin, a novel member of the complex. Approximately half of Aurora B in mitotic cells is complexed with INCENP, Borealin, and Survivin; and Bo... | ['Amino Acid Sequence', 'Animals', 'Binding Sites', 'Cell Cycle Proteins', 'Cell Division', 'Chromosomal Proteins, Non-Histone', 'Chromosomes', 'Humans', 'Inhibitor of Apoptosis Proteins', 'Macromolecular Substances', 'Microtubule-Associated Proteins', 'Mutation', 'Neoplasm Proteins', 'Nuclear Proteins', 'Recombinant F... | 15,249,581 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['D12.776.167'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D12.776.660.235', 'D12.776.664.235'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Ventilation system, indoor air quality, and health outcomes in Parisian modern office workers. | A cross-sectional study was carried out to determine the effect on health of exposure to different types of ventilation, taking indoor environmental measurements (IEMs) of major contaminants and aeroallergens into account. Three buildings ventilated with heating, ventilating, and air conditioning (HVAC), fan coil units... | ['Adult', 'Air Conditioning', 'Air Pollution, Indoor', 'Allergens', 'Cross-Sectional Studies', 'Epidemiologic Methods', 'Female', 'Humans', 'Male', 'Occupational Exposure', 'Occupational Health', 'Paris', 'Reproducibility of Results', 'Sick Building Syndrome', 'Surveys and Questionnaires', 'Ventilation'] | 9,417,840 | [['M01.060.116'], ['N06.230.150.050'], ['N06.850.460.100.080'], ['D23.050.063'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318', 'N06.850.520'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.460.350.600'], ['N01.400.525'], ['Z01.433.800', 'Z01.542.286.588'], ['E05... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Evaluation of mandibular transverse widths in patients affected by unilateral and bilateral cleft lip and palate using cone beam computed tomography. | OBJECTIVE: To evaluate the mandibular dental, alveolar, and skeletal transversal widths in patients affected by unilateral (UCLP) and bilateral (BCLP) cleft lip and palate and to compare the findings with a well-matched normal occlusion sample using cone beam computed tomography images.MATERIALS AND METHODS: The study ... | ['Adolescent', 'Alveolar Process', 'Case-Control Studies', 'Cephalometry', 'Child', 'Cleft Lip', 'Cleft Palate', 'Cone-Beam Computed Tomography', 'Cuspid', 'Dental Arch', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Male', 'Mandible', 'Molar', 'Retrospective Studies'] | 25,230,812 | [['M01.060.057'], ['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['M01.060.406'], ['C07.465.409.225', 'C07.465.525.164', 'C07.650.525.164', 'C16.131.8... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[An exceptional hepatic tumor]. | BACKGROUND: Hepatic localization of non Hodgkin's lymphoma is generally secondary. Primary localizations are rare.AIM: To report a rare case of primary hepatic lymphoma particular by its association with dermatopolymyositis.OBSERVATION: A 55-year-old woman with a past medical history of dermatopolymyositis diagnosed on... | ['Female', 'Humans', 'Liver Neoplasms', 'Lymphoma, Large B-Cell, Diffuse', 'Middle Aged'] | 21,136,369 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['C04.557.386.480.150.585', 'C15.604.515.569.480.150.585', 'C20.683.515.761.480.150.585'], ['M01.060.116.630']] | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The deepwater demersal ichthyofauna of the western Coral Sea. | The highly diverse deepwater demersal ichthyofauna of the western Coral Sea was first systematically surveyed in two exploratory voyages in 1985 and 1986, and these fish assemblages have not been investigated at the same level since. Only recently have catch data and specimens, obtained from these first voyages almost ... | ['Animal Distribution', 'Animals', 'Australia', 'Biodiversity', 'Fishes', 'Pacific Ocean', 'Species Specificity'] | 25,543,931 | [['F01.145.113.069', 'G16.049'], ['B01.050'], ['Z01.639.100', 'Z01.678.100.373'], ['G16.500.275.157.049', 'N06.230.124.049'], ['B01.050.150.900.493'], ['Z01.756.700'], ['G16.824']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Novel apparatus to measure hyperthermal heavy ion damage to DNA: strand breaks, base loss, and fragmentation. | We have developed a novel apparatus that allows us to irradiate nonvolatile organic films of high mass (1-100 microg range) spread out over a large surface area (42 cm(2)) with low energy (kT-100 eV) heavy ions and to quantitatively analyze the film substance via standard biochemical techniques afterwards. Here we disc... | ['Base Pair Mismatch', 'Computer-Aided Design', 'DNA', 'DNA Breaks', 'DNA Damage', 'DNA Fragmentation', 'Dose-Response Relationship, Radiation', 'Equipment Design', 'Equipment Failure Analysis', 'Heavy Ions', 'Particle Accelerators', 'Radiation Dosage', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 17,764,359 | [['G05.365.590.060'], ['L01.224.108.150', 'L01.296.110.150'], ['D13.444.308'], ['G05.200.210'], ['G05.200'], ['G05.200.230'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['E05.320'], ['E05.325.192'], ['G01.249.467'], ['E07.710.680'], ['E05.799.513', 'G01.750.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Tissue levels of lead in experimentally exposed zebra finches (Taeniopygia guttata) with particular attention on the use of feathers as biomonitors. | We tested experimentally whether zebra finch feathers can be used as a biomonitor for lead pollution, and we examined whether lead exposure influences the accumulation of zinc into feathers. Two groups of eight adult male zebra finches were dosed with, respectively, 0 and 25 ppm lead as lead acetate in their drinking w... | ['Animals', 'Environmental Exposure', 'Environmental Pollutants', 'Feathers', 'Kidney', 'Lead', 'Liver', 'Male', 'Muscle, Skeletal', 'Songbirds', 'Tissue Distribution', 'Zinc'] | 11,706,372 | [['B01.050'], ['N06.850.460.350'], ['D27.888.284'], ['A13.370'], ['A05.810.453'], ['D01.268.556.435', 'D01.552.544.435'], ['A03.620'], ['A02.633.567', 'A10.690.552.500'], ['B01.050.150.900.248.620.750'], ['G03.787.917', 'G07.690.725.949'], ['D01.268.556.940', 'D01.268.956.906', 'D01.552.544.940']] | ['Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Simvastatin lowers portal pressure in patients with cirrhosis and portal hypertension: a randomized controlled trial. | BACKGROUND & AIMS: Simvastatin improves liver generation of nitric oxide and hepatic endothelial dysfunction in patients with cirrhosis, so it could be an effective therapy for portal hypertension. This randomized controlled trial evaluated the effects of continuous simvastatin administration on the hepatic venous pres... | ['Adrenergic beta-Antagonists', 'Double-Blind Method', 'Female', 'Hemodynamics', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Hypertension, Portal', 'Hypolipidemic Agents', 'Liver Circulation', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Portal Pressure', 'Simvastatin'] | 19,208,350 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.186.071.202.370', 'D27.505.519.389.370', 'D27.505.954.557.500.202.370'], ['C06.552.494'],... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Neonicotinoids and bumblebees (Bombus terrestris): effects on nectar consumption in individual workers. | BACKGROUND: The objective of this study was to quantify whether the presence of three different neonicotinoid insecticides (imidacloprid, thiamethoxam or clothianidin) in sucrose solution results in antifeedant effects in individual worker bumblebees (Bombus terrestris), and, if so, whether this effect is reversible if... | ['Animals', 'Bees', 'Eating', 'Feeding Behavior', 'Guanidines', 'Imidazoles', 'Insecticides', 'Neonicotinoids', 'Nitro Compounds', 'Oxazines', 'Sucrose', 'Thiamethoxam', 'Thiazoles'] | 25,132,051 | [['B01.050'], ['B01.050.500.131.617.720.500.500.875.387'], ['G07.203.650.283', 'G10.261.330'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['D02.078.370'], ['D03.383.129.308'], ['D27.720.031.700.491', 'D27.888.723.491'], ['D03.383.464'], ['D02.640'], ['D03.383.533'], ['D09.698.629.305.770', 'D09.947.750.770'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Etiology of Gender Identity. | This article reviews the current literature characterizing potential factors associated with the etiologies of gender identity. The PubMed database was searched for all literature that assessed key elements affecting development of gender identity. Current models attribute gender identity etiology to endogenous biology... | ['Animals', 'Female', 'Gender Identity', 'Humans', 'Male', 'Pregnancy', 'Transsexualism'] | 31,027,542 | [['B01.050'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['F01.145.802.975.750']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tubular Network Formation by Mixing Amphiphilic Polypeptides with Differing Hydrophilic Blocks. | Artificial tubular networks are promising structures for biomaterial applications because of their large surface areas. A tubular network was formed by co-assembling two different amphiphilic polypeptides, poly(ethylene glycol)-b-(l-Leu-Aib)6 (PL12) and polysarcosine-b-(l-Leu-Aib)6 (SL12). They both have the same hydro... | ['Hot Temperature', 'Hydrophobic and Hydrophilic Interactions', 'Nanotubes', 'Peptides', 'Polyethylene Glycols', 'Sarcosine'] | 31,532,187 | [['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G02.409'], ['J01.637.512.850'], ['D12.644'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['D12.125.481.700.374']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The effect of mechanical load on tendon-to-bone healing in a rat model. | BACKGROUND: Joint motion is commonly prescribed after tendon repair surgeries such as rotator cuff repairs; however, the ideal rehabilitation program to optimize tendon-to-bone healing is unknown.HYPOTHESES: (1) Delayed loading would result in a mechanically stronger and better organized tendon-to-bone interface compar... | ['Animals', 'Apoptosis', 'Bone Density', 'Collagen', 'External Fixators', 'Fibrocartilage', 'Immobilization', 'Immunohistochemistry', 'Interleukin-1beta', 'Matrix Metalloproteinase 13', 'Models, Animal', 'Osteogenesis', 'Patellar Ligament', 'Rats', 'Rats, Sprague-Dawley', 'Stress, Mechanical', 'Tensile Strength', 'Tibi... | 24,692,434 | [['B01.050'], ['G04.146.954.035'], ['G11.427.100'], ['D05.750.078.280', 'D12.776.860.300.250'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['A02.165.308', 'A10.165.382.350'], ['E05.472'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.10... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Modified Mandibular Sagittal Split Osteotomy. | INTRODUCTION: Mandibular osteotomies aim to displace the dental arch to the necessary position, ideally without limitation, while preserving inferior alveolar nerve (IAN) function. Supraforaminal osteotomies offer nerve safety but limit the extent of advancement, whereas Epker and Obwegeser-Dal Pont osteotomies enable ... | ['Humans', 'Malocclusion', 'Mandible', 'Mandibular Advancement', 'Mandibular Nerve', 'Mandibular Osteotomy', 'Trigeminal Nerve Injuries'] | 30,608,375 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.793.494'], ['A02.835.232.781.324.502.632', 'A14.521.632'], ['E04.545.500', 'E06.645.500', 'E06.658.280'], ['A08.800.800.120.760.500'], ['E06.645.562.374'], ['C07.465.299.625.500.349', 'C10.292.200.875', 'C10.292.319.625.700.349', 'C10.900.300.218.775', 'C26.915.30... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The effect of adrenoblockaders on the rate of H3-catecholamine synthesis and uptake in the rat seminal duct]. | In the rat vas deferens alpha-adrenoblocking agent phentolamine (1-10(-6)M) and beta-adrenoblocking agent propranolol (1-10(-6)M) activated uptake of exogenous noradrenaline--H-3 by 37 and 47% respectively and synthesis of noradrenaline--H3 from thyrosin-H3 by 72 and 48%. The rate of noradrenaline-H3 synthesis from DOP... | ['Animals', 'Dihydroxyphenylalanine', 'Dopamine', 'Male', 'Norepinephrine', 'Phentolamine', 'Propranolol', 'Rats', 'Receptors, Adrenergic', 'Tyrosine', 'Vas Deferens'] | 1,240,062 | [['B01.050'], ['D02.092.311.200', 'D02.455.426.559.389.657.166.175.200', 'D12.125.072.050.685.400', 'D12.125.072.050.875.130'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.830', 'D02.455.426.559.389.657... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of small peptides or amino acids infused to a perfused area of the skin of Angora goats on mohair growth. | The effect of infusing dipeptides or their amino acids on mohair growth of Angora goats was investigated using a skin perfusion technique. Seven Angora wethers (average BW 24 +/- 2.5 kg) were implanted bilaterally with silicon catheters into the superficial branches of the deep circumflex iliac artery and vein and caro... | ['Amino Acids', 'Animals', 'Dipeptides', 'Goats', 'Hair', 'Leucine', 'Lysine', 'Male', 'Methionine', 'Perfusion', 'Skin'] | 12,002,317 | [['D12.125'], ['B01.050'], ['D12.644.456.345'], ['B01.050.150.900.649.313.500.380.513'], ['A17.360'], ['D12.125.070.637', 'D12.125.142.441'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.166.676'], ['E05.680'], ['A17.815']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Using clinical audit, qualitative data from patients and feedback from general practitioners to decrease delay in the referral of suspected colorectal cancer. | RATIONALE: There was local concern over possible delays in the diagnosis and referral of patients with suspected colorectal cancer and interest in understanding more about patients' experiences of diagnosis.AIMS AND OBJECTIVES: To use clinical audit, qualitative data from patients and feedback from general practitioner... | ['Colorectal Neoplasms', 'Feedback', 'Humans', 'Interviews as Topic', 'Medical Audit', 'Patients', 'Physicians, Family', 'Referral and Consultation', 'Time Factors', 'United Kingdom'] | 17,378,881 | [['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['L01.906.394.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['N04.761.700.250.5... | ['Diseases [C]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Airway closure and closing pressure during mechanical ventilation. | Six subjects without clinical evidence of lung disease were investigated for airway closure and airway closing pressure before and during fentanyl-thiopentone anesthesia with mechanical ventilation. Airway closure was measured by single breath and FRC by multiple breath nitrogen washout. Airway closing pressure was tak... | ['Aged', 'Female', 'Humans', 'Lung Volume Measurements', 'Male', 'Middle Aged', 'Pressure', 'Respiration, Artificial', 'Respiratory Physiological Phenomena'] | 7,468,117 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.386.700.485'], ['M01.060.116.630'], ['G01.374.715'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820'], ['G09.772']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Study on chondrogenesis of rabbit bone marrow-derived mesenchymal stem cells by centrifuge-tube culture in vitro]. | OBJECTIVE: To investigate the feasibility of constructing tissue engineered cartilage by inducing bone marrow-derived mesenchymal stem cells (MSCs) in centrifuge-tube culture.METHOD: By Percoll density gradient centrifuge and monolaryer culture in vitro MSCs were isolated from rabbit bone marrow and were purified. Some... | ['Animals', 'Cell Differentiation', 'Cells, Cultured', 'Chondrogenesis', 'Mesenchymal Stem Cells', 'Rabbits'] | 15,938,211 | [['B01.050'], ['G04.152'], ['A11.251'], ['G07.345.500.325.377.625.180', 'G11.427.578.180'], ['A11.329.830.500', 'A11.872.590.500'], ['B01.050.150.900.649.313.968.700']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structure and induction of a lysozyme gene from the tobacco hornworm, Manduca sexta. | Lysozyme is hypothesized to play a central role in initiating and maintaining the antibacterial defense response of Manduca sexta. We isolated a cDNA clone encoding a M. sexta lysozyme. Results of Northern blot analyses using this cDNA as a probe indicated that the abundance of lysozyme transcripts increased in seven t... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Blotting, Northern', 'Cloning, Molecular', 'DNA, Complementary', 'Enzyme Induction', 'Gene Expression Regulation, Enzymologic', 'Kinetics', 'Molecular Sequence Data', 'Moths', 'Muramidase', 'Oligonucleotide Probes', 'Organ Specificity', 'Peptidoglycan', 'RNA', 'Restr... | 7,517,269 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G05.308.320.200'], ['G05.308.320'], ['G01.374.661'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Vasoactive intestinal polypeptide (VIP) in children with neural crest tumours. | The concentration of vasoactive intestinal polypeptide (VIP) in plasma was measured in 22 children with neural crest tumours (NCT) during a 5-year period; the mean concentration of VIP in plasma was 22.5 pmol/l (interval 2.0-95.0 pmol/l). To establish a reference interval the plasma concentration of VIP was measured in... | ['Child', 'Child, Preschool', 'Diarrhea', 'Female', 'Ganglioneuroma', 'Gastrointestinal Hormones', 'Humans', 'Infant', 'Male', 'Neoplasms, Germ Cell and Embryonal', 'Neuroblastoma', 'Reference Values', 'Vasoactive Intestinal Peptide'] | 6,295,059 | [['M01.060.406'], ['M01.060.406.448'], ['C23.888.821.214'], ['C04.557.465.625.600.355', 'C04.557.470.670.355', 'C04.557.580.625.600.355'], ['D06.472.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04.557.465'], ['C04.557.465.625.600.590.650.550', 'C04.557.470.670.590.650.550', 'C04.557.580.6... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Acute stress disorder after myocardial infarction: prevalence and associated factors. | OBJECTIVE: To examine the prevalence of acute stress disorder (ASD) after a myocardial infarction (MI) and the factors associated with its development.METHODS: Of 1344 MI patients admitted to three Canadian hospitals, 474 patients did not meet the inclusion criteria and 393 declined participation in the study; 477 pati... | ['Aged', 'Confounding Factors, Epidemiologic', 'Depression', 'Female', 'Humans', 'Life Change Events', 'Male', 'Middle Aged', 'Models, Theoretical', 'Myocardial Infarction', 'Personality Inventory', 'Quebec', 'Regression Analysis', 'Risk Factors', 'Self Concept', 'Severity of Illness Index', 'Social Support', 'Socioeco... | 18,981,272 | [['M01.060.116.100'], ['N05.715.350.240', 'N06.850.490.718'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458.410'], ['M01.060.116.630'], ['E05.599'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['F04.711.647.513'], ['Z01.107.567.176.791'], [... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A rare case of paratesticular pleomorphic rhabdomyosarcoma diagnosed by fine needle aspiration: a case report. | Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of children and young adults. It represents 6.5% of all malignant tumors in pediatrics with an annual incidence of 4 to 7 cases per million children. Embryonal RMS arising in paratesticular region in young males is a common entity, however pleomorphic RMS in... | ['Adolescent', 'Biopsy, Fine-Needle', 'Humans', 'Lymphatic Metastasis', 'Male', 'Rhabdomyosarcoma', 'Scrotum', 'Soft Tissue Neoplasms'] | 19,790,247 | [['M01.060.057'], ['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.65... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Patient satisfaction, pain, and quality of life 4 months after displaced femoral neck fractures: a comparison of 663 fractures treated with internal fixation and 906 with bipolar hemiarthroplasty reported to the Norwegian Hip Fracture Register. | BACKGROUND: Primary arthroplasty and internal fixation are the two main options for treatment of displaced femoral neck fractures. Despite the fact that there have been several randomized studies, the optimal treatment in the elderly is still controversial. In the present study, based on data from the Norwegian Hip Fra... | ['Aged', 'Arthroplasty, Replacement, Hip', 'Female', 'Femoral Neck Fractures', 'Fracture Fixation, Internal', 'Humans', 'Male', 'Norway', 'Outcome Assessment, Health Care', 'Pain Measurement', 'Patient Satisfaction', 'Quality of Life', 'Registries', 'Reoperation', 'Surveys and Questionnaires', 'Treatment Outcome'] | 18,839,364 | [['M01.060.116.100'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['C26.404.061.425.500', 'C26.531.750.500', 'C26.558.276.425.500'], ['E04.555.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.816.374'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['E01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Solution-combustion synthesis of doped TiO2 | Photodynamic therapy has emerged as an alternative treatment for cutaneous leishmaniasis, and compounds with photocatalytic behavior are promising candidates to develop new therapeutic strategies for the treatment of this parasitic disease. Titanium dioxide TiO2 is a semiconductor ceramic material that shows excellent ... | ['Animals', 'Cell Survival', 'DNA Damage', 'Iron', 'Leishmania', 'Leishmaniasis', 'Macrophages, Peritoneal', 'Metal Nanoparticles', 'Mice', 'Microscopy, Electron, Transmission', 'Perylene', 'Photochemotherapy', 'Photosensitizing Agents', 'Reactive Oxygen Species', 'Spectrometry, Fluorescence', 'Titanium', 'Ultraviolet ... | 29,689,488 | [['B01.050'], ['G04.346'], ['G05.200'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['B01.268.475.868.488'], ['C01.610.752.300.500', 'C01.610.858.560', 'C01.920.813', 'C17.800.838.775.560'], ['A11.329.372.630', 'A11.627.482.630', 'A11.733.397.630', 'A15.382.670.522.630', 'A15.382.680.397.630'], ['J01.637... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[The change of activity of protective enzyme around sprout tumble of Pinellia ternate under high temperature stress]. | OBJECTIVE: To study the change of the activity of protective enzyme to avoid sprout tumble of Pinellia ternata.METHOD: A high temperature stress was given to P. ternata. Then the activity of protective enzyme (SOD, POD and CAT) and the content of membrane lipid peroxidation (MDA) were detected after different treating ... | ['Catalase', 'Heat-Shock Response', 'Hot Temperature', 'Malondialdehyde', 'Peroxidase', 'Pinellia', 'Plants, Medicinal', 'Superoxide Dismutase'] | 15,503,767 | [['D08.811.682.732.332'], ['G07.775.500'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['D02.047.700'], ['D08.811.682.732.700'], ['B01.650.940.800.575.912.250.618.050.750.500'], ['B01.650.560'], ['D08.811.682.881']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Differentiation of selves: Differentiating a fuzzy concept. | Notwithstanding the appeal of the "one size fits all" approach that Baumeister et al. propose, we argue that there is no panacea for improving group performance. The concept of "differentiation of selves" constitutes an umbrella term for similar seeming but actually different constructs. Even the same type of "differen... | ['Confusion', 'Group Processes', 'Humans', 'Self Concept'] | 28,355,798 | [['C10.597.606.337', 'C23.888.592.604.339', 'F01.700.250'], ['F01.829.316'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.747.792']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
MRI evaluation of ligaments and tendons of foot arch in talar dome osteochondral lesions. | Background There are no publications in literature describing an association between disorders of the ligaments and tendons supporting the foot arch and osteochondral lesions of the talus (OCLT). We believe there may be a correlation between the damage of these structures. Purpose To investigate the pathologies of main... | ['Adult', 'Aged', 'Ankle Injuries', 'Female', 'Foot', 'Foot Diseases', 'Humans', 'Ligaments, Articular', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Talus', 'Tendon Injuries', 'Tendons', 'Young Adult'] | 28,882,059 | [['M01.060.116'], ['M01.060.116.100'], ['C26.558.100'], ['A01.378.610.250'], ['C05.360', 'C17.800.321'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.513.514', 'A02.835.583.512', 'A10.165.669.514'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['A02.835.232.043.300.710.780'], ['C26.874'], ['A02.880'], ['M01.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cbx2 targets PRC1 to constitutive heterochromatin in mouse zygotes in a parent-of-origin-dependent manner. | Polycomb repressive complexes PRC1 and PRC2 regulate expression of genes involved in proliferation and development. In mouse early embryos, however, canonical PRC1 localizes to paternal pericentric heterochromatin (pat-PCH), where it represses transcription of major satellite repeats. In contrast, maternal PCH (mat-PCH... | ['Amino Acid Sequence', 'Animals', 'Binding Sites', 'Centromere', 'Chromosomal Proteins, Non-Histone', 'Embryo, Mammalian', 'Female', 'Gene Expression Regulation, Developmental', 'Heterochromatin', 'Histones', 'Inheritance Patterns', 'Male', 'Methyltransferases', 'Mice', 'Mice, Transgenic', 'Molecular Sequence Data', '... | 25,801,166 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['A11.284.430.106.279.345.190.160.165', 'G05.360.160.165'], ['D12.776.660.235', 'D12.776.664.235'], ['A16.254'], ['G05.308.310'], ['A11.284.430.106.279.345.190.160.180.383', 'D12.776.664.224.466', 'G05.360.160.180.383'], ['D12.776.157.687.48... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Acrolein induces endoplasmic reticulum stress and causes airspace enlargement. | BACKGROUND: Given the relative abundance and toxic potential of acrolein in inhaled cigarette smoke, it is surprising how little is known about the pulmonary and systemic effects of acrolein. Here we test the hypothesis whether systemic administration of acrolein could cause endoplasmic reticulum (ER) stress, and lung ... | ['Acrolein', 'Animals', 'Caspase 3', 'Endoplasmic Reticulum Stress', 'Gene Expression', 'Lung', 'Male', 'Protein Binding', 'Pulmonary Disease, Chronic Obstructive', 'Pulmonary Emphysema', 'Rats', 'Rats, Sprague-Dawley', 'Unfolded Protein Response', 'Vascular Endothelial Growth Factor A'] | 22,675,432 | [['D02.047.122'], ['B01.050'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['G04.434'], ['G05.297'], ['A04.411'], ['G02.111.679', 'G03.808'], ['C08.381.495.389'], ['C08.381.495.389.750'], ['B01.050.150.900.649.313.992.635.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid Morphological and Cytoskeletal Response to Microgravity in Human Primary Macrophages. | The FLUMIAS (Fluorescence-Microscopic Analyses System for Life-Cell-Imaging in Space) confocal laser spinning disk fluorescence microscope represents a new imaging capability for live cell imaging experiments on suborbital ballistic rocket missions. During the second pioneer mission of this microscope system on the TEX... | ['Actin Cytoskeleton', 'Actins', 'Cell Line', 'Cell Nucleus', 'Cytoplasm', 'Cytoskeleton', 'Humans', 'Lysosomes', 'Macrophages', 'Microscopy, Confocal', 'Microscopy, Fluorescence', 'Monocytes', 'Space Flight', 'Weightlessness'] | 31,096,581 | [['A11.284.430.214.190.750.050'], ['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.214'], ['A11.284.430.214.190.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.214.190.875.190.550'], ['A11.329.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Possible mechanisms of elevation of serum secretory immunoglobulin A in liver diseases. | In order to investigate possible mechanisms of elevation of serum secretory immunoglobulin A (sIgA) in liver diseases, human liver specimens were applied to immunohistochemical study of immunoglobulin A, secretory component, and J chain, which are components of sIgA. In the cases of chronic hepatitis with high serum sI... | ['Bile Canaliculi', 'Cell Membrane', 'Histocytochemistry', 'Humans', 'Immunoglobulin A, Secretory', 'Immunoglobulin Fragments', 'Immunoglobulin J-Chains', 'Kupffer Cells', 'Liver', 'Liver Diseases', 'Microscopy, Electron', 'Secretory Component'] | 3,085,476 | [['A03.159.183.158.125', 'A03.620.150.125'], ['A11.284.149'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.026.030', 'D12.776.124.790.651.1... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of kidney transplantation on sleep-disordered breathing in patients with End Stage Renal Disease: a polysomnographic study. | BACKGROUND: Sleep-disordered breathing (SDB) is common in patients with end-stage renal disease (ESRD). SDB is associated with comorbidities such as hypertension, diabetes mellitus, and obesity, interplaying with metabolic derangements in the form of uremia, acidosis, and hypervolemia. Renal transplant has been observe... | ['Adult', 'Female', 'Humans', 'Hypertension', 'India', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Male', 'Polysomnography', 'Prevalence', 'Renal Dialysis', 'Sleep Apnea Syndromes'] | 29,680,422 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['Z01.252.245.393'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['E01.370.520.625'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Altered activity of heme biosynthesis pathway enzymes in individuals chronically exposed to arsenic in Mexico. | Our objective was to evaluate the activities of some enzymes of the heme biosynthesis pathway and their relationship with the profile of urinary porphyrin excretion in individuals exposed chronically to arsenic (As) via drinking water in Region Lagunera, Mexico. We selected 17 individuals from each village studied: Ben... | ['Arsenic', 'Creatinine', 'Environmental Exposure', 'Enzymes', 'Female', 'Fluorides', 'Heme', 'Humans', 'Hydroxymethylbilane Synthase', 'Male', 'Mexico', 'Porphyrins', 'Time Factors', 'Uroporphyrinogen Decarboxylase'] | 10,350,189 | [['D01.268.513.249'], ['D03.383.129.308.207'], ['N06.850.460.350'], ['D08.811'], ['D01.248.497.158.380', 'D01.303.350.300'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.225.575'], ['Z... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[Isolated, unilateral paresis of the phrenic nerve after pneumonia and pleurisy]. | Unilateral diaphragmatic paralysis has many causes. Tumor and trauma are the two most frequent identifiable causes. Infectious processes involving the lung and/or mediastinum may result in temporary or permanent diaphragmatic paralysis. We report the case of an 81-year old man who suffered from right-sided pneumonia fo... | ['Aged', 'Aged, 80 and over', 'Diagnosis, Differential', 'Follow-Up Studies', 'Functional Laterality', 'Humans', 'Male', 'Phrenic Nerve', 'Pleurisy', 'Pneumonia', 'Reaction Time', 'Respiratory Paralysis'] | 12,242,966 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.171'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800.720.150.700'], ['C01.748.582', 'C08.528.735', 'C08.730.582'], ['C0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Vaginal absorption of two estriol preparations. A comparative study in postmenopausal women. | In a comparative randomized cross-over study the absorption of a single dose of 0.5 mg estriol from a vaginal cream or a vaginal suppository (OvestinR, Organon, The Netherlands) was studied. Eight healthy postmenopausal women participated and the preparations were given with an interval of 14 days. Blood sampling was p... | ['Absorption', 'Clinical Trials as Topic', 'Estriol', 'Female', 'Follicle Stimulating Hormone', 'Humans', 'Luteinizing Hormone', 'Menopause', 'Middle Aged', 'Suppositories', 'Vagina', 'Vaginal Creams, Foams, and Jellies'] | 6,421,082 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D04.210.500.365.415.331', 'D06.472.334.851.437.750'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['B01.050.150.900.649.31... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Platelet agglutinating protein p37 causes platelet agglutination through its binding to membrane glycoprotein IV. | A 37 kDa platelet agglutinating protein (PAP p37) has previously been shown to be present in a subset of patients with thrombotic thrombocytopenic purpura and has been purified from their plasma. Using solubilized platelet membrane proteins from normal donors, it was shown by Western blotting that 125I-p37 bound to a m... | ['Antibodies', 'Antibodies, Monoclonal', 'Blood Proteins', 'Blotting, Western', 'Humans', 'Iodine Radioisotopes', 'Platelet Aggregation', 'Platelet Membrane Glycoproteins', 'Protein Binding', 'Purpura, Thrombotic Thrombocytopenic'] | 2,024,231 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['B01.050.150.900.649.3... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Severe deficiency of VWF-cleaving protease (ADAMTS13) activity defines a distinct population of thrombotic microangiopathy patients. | BACKGROUND: Severe deficiency of ADAMTS13 activity is a biologic risk factor for thrombotic microangiopathy (TMA). It was hypothesized that severe ADAMTS13 deficiency is associated with a distinct TMA subpopulation.STUDY DESIGN AND METHODS: ADAMTS13 activity before treatment was determined retrospectively in 107 adult ... | ['ADAM Proteins', 'ADAMTS13 Protein', 'Creatinine', 'Humans', 'Metalloendopeptidases', 'Plasma Exchange', 'Remission Induction', 'Retrospective Studies', 'Thrombosis'] | 14,962,303 | [['D08.811.277.656.675.374.102', 'D09.400.430.500', 'D12.776.395.033'], ['D08.811.277.656.675.374.102.500.813', 'D09.400.430.500.500.813', 'D12.776.395.033.500.813', 'D12.776.860.300.085.813'], ['D03.383.129.308.207'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.480', 'D08.811.277.656.675.374... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A novel inducer of Roseobacter motility is also a disruptor of algal symbiosis. | Silicibacter sp. strain TM1040, a member of the Roseobacter clade, forms a symbiosis with unicellular phytoplankton, which is inextricably linked to the biphasic "swim or stick" lifestyle of the bacteria. Mutations in flaC bias the population toward the motile phase. Renewed examination of the FlaC(-) strain (HG1016) u... | ['Biofilms', 'Coumaric Acids', 'Escherichia coli', 'Flagellin', 'Gene Expression Regulation, Bacterial', 'Lignin', 'Movement', 'Mutation', 'Phenylacetates', 'Phytoplankton', 'Propionates', 'Roseobacter', 'Symbiosis'] | 23,161,030 | [['A20.593', 'G06.120'], ['D02.241.223.200.210'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.380'], ['G05.308.300'], ['D05.750.078.562.180.515', 'D05.750.078.687', 'D20.538', 'D25.720.099.687', 'J01.637.051.720.099.687'], ['G07.568', 'G11.427.410'], ['G05.365.590'], ['D02.241.223.601'], ['B05... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Efficacy and safety of endoscopic biliary lithotripsy using FREDDY laser with a radiopaque mark under fluoroscopic guidance. | To date no clinic trials have reported on the safety and effectiveness of the use of a frequency-doubled double pulse neodymium YAG (FREDDY) laser with a radiopaque mark under fluoroscopic guidance to treat bile duct stones that are untreatable by conventional endoscopic therapy. We report the cases of 30 patients with... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Fluoroscopy', 'Gallstones', 'Humans', 'Lasers, Solid-State', 'Lithotripsy, Laser', 'Male', 'Middle Aged', 'Treatment Outcome'] | 21,833,900 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350.700.225'], ['C06.130.409.633', 'C06.130.564.332.500', 'C23.300.175.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.490.490', 'E07.710.520.490'], ['E02.594.550', 'E02.600.500', 'E04.014.520.550', 'E04.943.500.500'], ['M01.060... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The psychological impact of being on a monitoring pathway for localised prostate cancer: A UK-wide mixed methods study. | OBJECTIVE: To address concerns over the psychological impact of being on a monitoring pathway following prostate cancer (PCa) diagnosis, this study compared the psychological status of men on active surveillance (AS) or watchful waiting (WW) with men on active treatment (AT) and explored psychological adjustment in men... | ['Adult', 'Aged', 'Cross-Sectional Studies', 'Decision Making', 'Disease Progression', 'Humans', 'Male', 'Mental Health', 'Middle Aged', 'Patient Preference', 'Prostatic Neoplasms', 'United Kingdom', 'Watchful Waiting'] | 31,132,801 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F02.463.785.373'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.418', 'N01.400.500'], ['M01.060.116.630'], ['F01.100.150.750.625.500', 'F01.145.488.887.625.500', 'N04.45... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Metabolic Parameters, Weight Loss, and Comorbidities 4 Years After Roux-en-Y Gastric Bypass and Sleeve Gastrectomy. | BACKGROUND: Sleeve gastrectomy (LSG) is now the predominant bariatric surgery performed, yet there is limited long-term data comparing important outcomes between LSG and Roux-en-Y gastric bypass (RYGB). This study compares weight loss and impact on comorbidities of the two procedures.METHODS: We retrospectively evaluat... | ['Blood Pressure', 'Body Weight', 'Comorbidity', 'Gastrectomy', 'Gastric Bypass', 'Humans', 'Obesity, Morbid', 'Retrospective Studies', 'Treatment Outcome', 'Weight Loss'] | 29,909,517 | [['E01.370.600.875.249', 'G09.330.380.076'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['N05.715.350.225', 'N06.850.490.687'], ['E04.210.419'], ['E02.650.500.062.249', 'E04.035.398.385', 'E04.062.249', 'E04.210.457.430'], ['B01.050.150.900.649.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pitfalls in the management of penetrating chest trauma. | A prospective study designed specifically to analyze errors in management and iatrogenic complications was conducted on 234 consecutive patients with penetrating chest trauma. Eleven percent of penetrating pleural injuries were incorrectly diagnosed on initial physical and radiologic examination, but this led to wrong ... | ['Blood Vessels', 'Diagnostic Errors', 'Drainage', 'Female', 'Heart Injuries', 'Humans', 'Male', 'Mediastinum', 'Pleura', 'Prospective Studies', 'Thoracic Injuries', 'Wounds, Penetrating'] | 2,929,860 | [['A07.015'], ['E01.354', 'N02.421.450.280'], ['E02.309', 'E04.237'], ['C26.891.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.923.761.800.500'], ['A04.716', 'A10.615.789.736'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C26.891'], ['C26.986']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Center differences and cross-national invariance in help-seeking for panic disorder. A report from the cross-national collaborative panic study. | Help-seeking behaviour for treatment of panic disorder was investigated in the sample of the Cross-National Collaborative Panic Study Second Phase. A total of 1168 patients were entered into this trial in 14 countries. Although there were significant center differences in prior treatment and utilization of health servi... | ['Adult', 'Alprazolam', 'Cross-Cultural Comparison', 'Cross-Sectional Studies', 'Female', 'Humans', 'Imipramine', 'Incidence', 'Male', 'Panic Disorder', 'Patient Acceptance of Health Care'] | 1,621,138 | [['M01.060.116'], ['D03.633.100.079.080.030'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.300.240.485'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Constitutive integrin activation on tumor cells contributes to progression of leptomeningeal metastases. | Leptomeningeal metastases are a serious neurological complication in cancer patients and associated with a dismal prognosis. Tumor cells that enter the subarachnoid space adhere to the leptomeninges and form tumor deposits. It is largely unknown which adhesion molecules mediate tumor cell adhesion to leptomeninges. We ... | ['Animals', 'Cell Adhesion', 'Cell Line, Tumor', 'Disease Progression', 'Integrins', 'Male', 'Meningeal Neoplasms', 'Mice', 'Mice, Inbred DBA', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma'] | 16,533,879 | [['B01.050'], ['G04.022'], ['A11.251.210.190', 'A11.251.860.180'], ['C23.550.291.656'], ['D12.776.543.750.705.408'], ['C04.588.614.250.580', 'C10.551.240.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.500', 'B01.050.150.900.649.313.992.635.505.500.400.500'], ['C04.557.337.428.600', 'C15.6... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Early colonization of functional groups of microbes in the infant gut. | The colonization of the infant gut is crucial for early life development. Although the composition and diversity of the infant gut microbiota (GM) has been well described at a taxonomic level, functional aspects of this ecosystem remain unexplored. In the infant gut, lactate is produced by a number of bacteria and play... | ['Bacteria', 'Fatty Acids, Volatile', 'Feces', 'Female', 'Fermentation', 'Gastrointestinal Microbiome', 'Humans', 'Infant', 'Infant, Newborn', 'Intestinal Mucosa', 'Intestines', 'Male', 'Phylogeny'] | 27,059,115 | [['B03'], ['D10.251.400'], ['A12.459'], ['G02.111.158.249', 'G03.191.249'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124'], ['G05.697', 'G16.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Named Groups [M]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Association of microRNA-7 and its binding partner CDR1-AS with the prognosis and prediction of 1st | The large number of non-coding RNAs (ncRNAs) and their breadth of functionalities has fuelled many studies on their roles in cancer. We previously linked four microRNAs to breast cancer prognosis. One of these microRNAs, hsa-miR-7, was found to be regulated by another type of ncRNA, the circular non-coding RNA (circRNA... | ['Adult', 'Aged', 'Breast Neoplasms', 'Cell Line, Tumor', 'Disease-Free Survival', 'Gene Expression Regulation, Neoplastic', 'Humans', 'MicroRNAs', 'Middle Aged', 'RNA, Long Noncoding', 'Recurrence', 'Tamoxifen'] | 29,941,867 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['G05.308.370'], ['B01.050.150.900.649.313.988.40... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cooperative Binding of Stromal Interaction Molecule 1 (STIM1) to the N and C Termini of Calcium Release-activated Calcium Modulator 1 (Orai1). | Calcium flux through store-operated calcium entry is a central regulator of intracellular calcium signaling. The two key components of the store-operated calcium release-activated calcium channel are the Ca(2+)-sensing protein stromal interaction molecule 1 (STIM1) and the channel pore-forming protein Orai1. During sto... | ['Calcium Channels', 'HEK293 Cells', 'Humans', 'Ion Channel Gating', 'Ions', 'Membrane Proteins', 'Mutant Proteins', 'Neoplasm Proteins', 'ORAI1 Protein', 'Protein Binding', 'Protein Structure, Tertiary', 'Stromal Interaction Molecule 1'] | 26,546,674 | [['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.820.400', 'G04.835.400', 'G07.265.625'], ['D01.248.497'], ['D12.776.543'], ['D12.776.602'], ['D12.776.624'], ['D12.776.157.530.400.150.74... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neuropilin-2 promotes extravasation and metastasis by interacting with endothelial á5 integrin. | Metastasis, the leading cause of cancer death, requires tumor cell intravasation, migration through the bloodstream, arrest within capillaries, and extravasation to invade distant tissues. Few mechanistic details have been reported thus far regarding the extravasation process or re-entry of circulating tumor cells at m... | ['Adenocarcinoma', 'Animals', 'Carcinoma, Renal Cell', 'Cell Adhesion', 'Cell Line, Tumor', 'Cell Movement', 'Endothelial Cells', 'Female', 'Human Umbilical Vein Endothelial Cells', 'Humans', 'Integrin alpha5', 'Kidney Neoplasms', 'Male', 'Mice', 'Mice, Nude', 'Neoplasm Invasiveness', 'Neoplasm Metastasis', 'Neoplastic... | 23,689,123 | [['C04.557.470.200.025'], ['B01.050'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['G04.022'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['A11.436.275'], ['A11.436.275.682'], ['... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Prevalence of the epilepsies in children and adolescents. | The prevalence of epilepsy in children and adolescents from birth through age 19 years was determined for residents of two counties in central Oklahoma. Cases, identified from hospitals, clinics, private physicians' offices, and EEG laboratory and emergency room records, numbered 1,159, yielding a prevalence rate of 4.... | ['Adolescent', 'Adult', 'African Continental Ancestry Group', 'Age Factors', 'Child', 'Child, Preschool', 'Developmental Disabilities', 'Epilepsy', 'European Continental Ancestry Group', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Movement Disorders', 'Oklahoma', 'Sex Factors'] | 2,463,913 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.100'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['M01.060.406.448'], ['F03.625.421'], ['C10.228.140.490'], ['M01.686.508.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C10.228.662'], ['Z01.107.567.875.510.5... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Phase I/II study of the Src inhibitor dasatinib in combination with erlotinib in advanced non-small-cell lung cancer. | PURPOSE: Src family kinase (SFK) proteins are frequently activated in cancer and can coordinate tumor cell growth, survival, invasion, and angiogenesis. Given the importance of SFK signaling in cancer, known cooperation between SFK and epidermal growth factor receptor (EGFR) signaling, and efficacy of EGFR inhibitors, ... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Biomarkers, Pharmacological', 'Carcinoma, Non-Small-Cell Lung', 'Dasatinib', 'Drug Administration Schedule', 'Drug-Related Side Effects and Adverse Reactions', 'ErbB Receptors', 'Erlotinib Hydrochloride', 'Female', 'Fibroblast Growth Factor 2', 'Human... | 20,142,592 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D23.101.137'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['D02.886.675.184', 'D03.383.129.708.198', 'D03.383.742.148'], ['E02.319.283'], ['C25.100'], ['D08.811.913.696.620.682... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Non-elective intra-coronary stenting: are the clinical outcomes comparable to elective stenting at 6 months? | The aim of this study was to compare prospectively the clinical outcome of patients treated with intra-coronary stents as a non-elective/bailout procedure for acute or threatened vessel closure, with those undergoing elective stenting at 6 months. Sixty-four patients (60.2+/-11.7 y) who underwent non-elective stenting ... | ['Aged', 'Angina, Unstable', 'Angioplasty, Balloon, Coronary', 'Coronary Angiography', 'Emergencies', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Prospective Studies', 'Recurrence', 'Retreatment', 'Stents', 'Survival Analysis', 'Treatment Outcome'] | 10,574,396 | [['M01.060.116.100'], ['C14.280.647.187.150', 'C14.907.585.187.150', 'C23.888.592.612.233.500.150'], ['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['E01.370.350.130... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Regularities of karyotypic evolution during stepwise amplification of genes determining drug resistance. | Analysis of chromosomal alterations during stepwise development of mdr1, dhfr, or CAD gene amplifications in a large number of independently selected Djungarian hamster DM-15 and murine P388 sublines revealed typical patterns of karyotypic evolution, specific for multiplication of each of these genes in each cell type.... | ['Animals', 'Biological Evolution', 'Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing)', 'Cell Line', 'Chromosome Aberrations', 'Cricetinae', 'Drug Resistance', 'Gene Amplification', 'Karyotyping', 'Leukemia P388', 'Tetrahydrofolate Dehydrogenase', 'Tumor Cells, Cultured'] | 1,374,512 | [['B01.050'], ['G05.045', 'G16.075'], ['D08.811.464.259.400.300'], ['A11.251.210'], ['C23.550.210', 'G05.365.590.175'], ['B01.050.150.900.649.313.992.635.075.250'], ['G07.690.773.984'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bacillus subtilis DNA polymerases, PolC and DnaE, are required for both leading and lagging strand synthesis in SPP1 origin-dependent DNA replication. | Firmicutes have two distinct replicative DNA polymerases, the PolC leading strand polymerase, and PolC and DnaE synthesizing the lagging strand. We have reconstituted in vitro Bacillus subtilis bacteriophage SPP1 è-type DNA replication, which initiates unidirectionally at oriL. With this system we show that DnaE is not... | ['Bacillus subtilis', 'Bacterial Proteins', 'Bacteriophages', 'Base Sequence', 'DNA Polymerase III', 'DNA Primase', 'DNA Replication', 'DNA, Single-Stranded', 'DNA, Viral', 'DNA-Binding Proteins', 'DNA-Directed DNA Polymerase', 'Electrophoresis, Agar Gel', 'Protein Binding', 'Replication Origin'] | 28,575,448 | [['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D12.776.097'], ['B04.123'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.913.696.445.308.300.235'], ['D08.811.913.696.445.735.270.375'], ['G02.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Rationale for the update of the European Pharmacopoeia general chapter 2.2.48. Raman spectroscopy. | Raman spectroscopy technique is widely used for the identification and characterisation of materials in the laboratory environment and, increasingly, for off-line, at-line, in-line and online Process Analytical Technologies (PAT) applications. The wide range of currently available Raman technologies had led to the requ... | ['Calibration', 'Chemistry, Pharmaceutical', 'Europe', 'Pharmacopoeias as Topic', 'Spectrum Analysis, Raman'] | 26,830,165 | [['E05.978.155'], ['H01.158.703.007', 'H01.181.466'], ['Z01.542'], ['L01.178.682.192.836.749'], ['E05.196.822.860', 'E05.196.867.890']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 |
Adherence to bisphosphonate therapy and fracture rates in osteoporotic women: relationship to vertebral and nonvertebral fractures from 2 US claims databases. | OBJECTIVE: To characterize the relationships between adherence (complance and persistence) to bisphosphonate therapy and risk of specific fracture types in postmenopausal women.PATIENTS AND METHODS: Data were collected from 45 employers and 100 health plans in the continental United States from 2 claims databases durin... | ['Aged', 'Diphosphonates', 'Drug Prescriptions', 'Female', 'Follow-Up Studies', 'Hip Fractures', 'Humans', 'Incidence', 'Insurance Claim Review', 'Middle Aged', 'Osteoporosis, Postmenopausal', 'Patient Compliance', 'Retrospective Studies', 'Risk Factors', 'Spinal Fractures', 'Wrist Injuries'] | 16,901,023 | [['M01.060.116.100'], ['D02.705.429.500'], ['E02.319.307', 'N02.421.668.778.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.5... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Massive hemoptysis, a presentation of invasion of aneurysm of descending aorta to bronchopulmonary tree. | Aortobronchial (AB) fistula is a rare disease, which is presented with massive hemoptysis; lethal if not treated. It should be suspected in any patient who presents with massive hemoptysis and had previous thoracic aortic surgery, but even it may be seen in patients without any history of operation on the thoracic aort... | ['Adult', 'Aged, 80 and over', 'Aorta, Thoracic', 'Aortic Aneurysm, Thoracic', 'Bronchial Fistula', 'Female', 'Hemoptysis', 'Humans', 'Male', 'Severity of Illness Index', 'Vascular Fistula'] | 25,365,623 | [['M01.060.116'], ['M01.060.116.100.080'], ['A07.015.114.056.372'], ['C14.907.055.239.125', 'C14.907.109.139.125'], ['C08.127.196', 'C08.702.196', 'C23.300.575.687.225'], ['C08.381.348', 'C23.550.414.896', 'C23.888.852.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980.438.475.456.500', 'N05.715.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Work-related skin disease in the plastics industry. | In a survey of a representative sample of workers taken at each of four different plastics manufacturers, 122 completed self-administered questionnaires were obtained. Twenty-six respondents (21.3%) met the case definition for having a work-related skin disorder during the preceding year. Sixteen (61.5%) cases indicate... | ['Adult', 'Aged', 'Confidence Intervals', 'Dermatitis, Occupational', 'Female', 'Formaldehyde', 'Hand Dermatoses', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Odds Ratio', 'Ohio', 'Plastics', 'Polyvinyl Chloride', 'Risk Factors', 'Sex Factors', 'Surveys and Questionnaires'] | 9,099,355 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['C17.800.174.255.700', 'C17.800.815.255.700', 'C24.270'], ['D02.047.407'], ['C17.800.338'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Interpretation of surface EMGs in children with cerebral palsy: An initial study using a fuzzy expert system. | Surface EMG detected simultaneously at different muscles has become an important tool for analysing the gait of children with cerebral palsy (CP), as it offers essential information about muscular coordination. However, the interpretation of surface EMG is a difficult task that assumes extensive knowledge and experienc... | ['Cerebral Palsy', 'Child', 'Child, Preschool', 'Electromyography', 'Expert Systems', 'Feasibility Studies', 'Female', 'Fuzzy Logic', 'Gait Disorders, Neurologic', 'Humans', 'Male', 'Muscle, Skeletal', 'Neural Networks, Computer', 'Pattern Recognition, Automated', 'Reproducibility of Results'] | 16,450,406 | [['C10.228.140.140.254'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.405.255', 'E01.370.530.255'], ['L01.224.050.375.190'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250'], ['C10.597.404', 'C23.888.592.413'], ['B01.050.150.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Humanities [K]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Assessing levels of knowledge on the principles of pain management during post-graduate education of physicians in Poland. | UNLABELLED: Treating chronic pain forms an integral part of patient care where a doctor's level of expertise is important for ensuring an adequately pain-free life. The aim of the study, therefore, was to assess the level of knowledge in pain management among doctors during their post-graduate education; some of whom w... | ['Adult', 'Clinical Competence', 'Education, Medical, Graduate', 'Female', 'Humans', 'Male', 'Pain Management', 'Physicians', 'Poland', 'Surveys and Questionnaires'] | 23,311,819 | [['M01.060.116'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.358.337.350', 'I02.358.399.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.745', 'N04.590.607.500'], ['M01.526.485.810', 'N02.360.810'], ['Z01.542.248.679'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Splenic rupture in infectious mononucleosis]. | A 22 year old male with infectious mononucleosis, who stated a history of trauma to his left thoracic wall, developed an acute abdomen with symptoms of shock. A ruptured spleen was suspected. This working diagnosis, which was supported by ultrasound led to a splenectomy the initial diagnosis. The case report of this ra... | ['Abdomen, Acute', 'Adult', 'Diagnosis, Differential', 'Emergencies', 'Humans', 'Infectious Mononucleosis', 'Male', 'Splenectomy', 'Splenic Rupture', 'Thoracic Injuries', 'Wounds, Nonpenetrating'] | 8,571,629 | [['C23.888.592.612.054.200', 'C23.888.821.030.249'], ['M01.060.116'], ['E01.171'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.925.256.466.313.400', 'C15.378.553.381', 'C15.604.515.516', 'C20.683.515.515'], ['E04.726'], ['C15.604.744.742', 'C26.017.680',... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Systems versus performance problems: a peer review organization's perspective. | An analysis of Ohio's Medicare data base by the state's Peer Review Organization, using the most common diagnosis-related group in the Medicare population (heart failure and shock), from January 1, 1989 to January 1, 1991, identified 72 cases with confirmed quality-of-care problems. The analysis was performed to determ... | ['Clinical Competence', 'Efficiency', 'Health Services Research', 'Heart Failure', 'Hospitals', 'Humans', 'Medical Staff, Hospital', 'Medicare', 'Ohio', 'Professional Review Organizations', 'Quality Assurance, Health Care', 'Shock', 'Systems Analysis', 'United States'] | 1,298,211 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['F02.784.692.351', 'N04.452.209'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['C14.280.434'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.630.490', 'M01.526.485.740.422', 'N02.360.630.490', 'N02.360.740.422'], ['N03.219.52... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Modeling a macrocyclic bis[spirodiepoxide] strategy to erythronolide A. | A concise route to functionalized 14-membered macrolides related to erythronolide A was achieved. Key steps include the simultaneous formation of bis[allenic] substrates, efficient macrolactonization, highly stereoselective oxidation to the corresponding bis[spirodiepoxide], and nucleophilic spirodiepoxide opening. The... | ['Crystallography, X-Ray', 'Epoxy Compounds', 'Erythromycin', 'Macrocyclic Compounds', 'Models, Molecular', 'Molecular Structure', 'Oxidation-Reduction', 'Stereoisomerism'] | 19,725,523 | [['E05.196.309.742.225'], ['D02.355.291.411'], ['D02.540.576.500.992'], ['D04.345'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['G02.700', 'G03.295.531'], ['G02.607.445.682']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mechanisms of blood clotting activation in inflammation: the role of mononuclear phagocytes. | The authors review the procoagulant role of mononuclear phagocytes in the activation of blood clotting. Although the intrinsic pathway via the contact system has been considered the most important mechanism leading to fibrin formation, at least in acute inflammation, recent studies strongly suggest a role for the cells... | ['Blood Coagulation', 'Gastrointestinal Neoplasms', 'Graft Rejection', 'Humans', 'Hypersensitivity, Delayed', 'Inflammation', 'Macrophages', 'Monocytes', 'Phagocytes', 'Toxemia', 'Transplantation, Homologous'] | 4,066,203 | [['G09.188.390.150'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543.418'], ['C23.550.470'], ['A11.329.372', 'A11.627.482', 'A11.733.397', 'A15.382.670.522', 'A15.382.680.397'], ['A11.118.637.555.652', 'A11.148.580', 'A11.627.624', 'A11... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitation of helper factor activity. II. Inhibition of antibody binding. | A sensitive direct assay has been developed to quantitate antigen specific helper factors (ThF). The assay depends on the ability of ThF to block the binding of free antibody to immobilized antigen. It has been used to follow the course of purification of ThF produced in short-term cultures of in vitro primed helper ce... | ['Animals', 'Binding Sites, Antibody', 'Binding, Competitive', 'Chickens', 'Epitopes', 'Histocompatibility Antigens Class II', 'Immunoglobulin G', 'Interleukin-2', 'Mice', 'Mice, Inbred CBA', 'Radioimmunoassay', 'T-Lymphocytes, Helper-Inducer'] | 6,199,430 | [['B01.050'], ['G02.111.570.060.425.079', 'G02.111.570.120.408', 'G12.122.232', 'G12.125'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D23.050.550'], ['D12.776.395.550.509', 'D12.776.543.550.440', 'D23.050.301.500.400', 'D23.050.705.552.410']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reforming beneficiary cost sharing to improve Medicare performance. | This paper explores options for reforming Medicare cost sharing in an effort to provide better financial protection for those beneficiaries with the greatest health care needs. Using data from the Health and Retirement Study (HRS) and the Medicare Current Beneficiary Survey (MCBS), we consider how unified annual deduct... | ['Aged', 'Aged, 80 and over', 'Cost Sharing', 'Health Expenditures', 'Humans', 'Medicare', 'Middle Aged', 'Models, Economic', 'United States'] | 21,155,416 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['N03.219.151.170', 'N03.219.521.576.090'], ['N03.219.151.450', 'N05.300.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.346.506.564.663', 'N03.219.521.576.343.840', 'N03.706.615.696'], ['M01.060.116.630'], ['E05.318.740.500.600', 'E05.599.835.890', '... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The human neural cell adhesion molecule L1 functions as a costimulatory molecule in T cell activation. | L1 is a neural cell adhesion molecule (CAM) known to be important for normal neurological development. Despite being described as a neural CAM, we have documented L1 expression by antigen-presenting cells of myelomonocytic origin. Here we demonstrate that L1 can function as a costimulatory molecule in T cell activation... | ['Animals', 'Antibodies, Monoclonal', 'CD3 Complex', 'Cell Line', 'Dendritic Cells', 'Humans', 'In Vitro Techniques', 'Leukocyte L1 Antigen Complex', 'Lymphocyte Activation', 'Lymphocyte Culture Test, Mixed', 'Membrane Glycoproteins', 'Neural Cell Adhesion Molecules', 'Phytohemagglutinins', 'T-Lymphocytes', 'Transfecti... | 10,741,412 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264.894.095', 'D23.101.100.894.095'], ['A11.251.210'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D12.776.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of increased intracranial pressure in brain surface microcirculation in rats. | The effects of increased intracranial pressure (ICP) on pial vessel diameters were investigated in rats using a cranial window and fluorescence microscopy. The brain surface was superfused with mock cerebro-spinal fluid (CSF) at a constant rate (5 ml/h), and the ICP was raised up to 20 mmHg by elevating a CSF-reservoir... | ['Animals', 'Arterioles', 'Blood-Brain Barrier', 'Brain', 'Intracranial Pressure', 'Male', 'Microcirculation', 'Microscopy, Fluorescence', 'Rats', 'Rats, Sprague-Dawley', 'Vasoconstriction'] | 7,847,139 | [['B01.050'], ['A07.015.114.060', 'A07.015.461.080'], ['A07.035', 'A08.186.211.035'], ['A08.186.211'], ['G11.561.170.505'], ['G09.330.100.645'], ['E01.370.350.515.458', 'E05.595.458'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['G09.330.380.925']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Environmental tobacco smoke exposure and periodontitis prevalence among nonsmokers in the hispanic community Health Study/Study of Latinos. | OBJECTIVE: To describe self-reported exposure to environmental tobacco smoke (ETS) and its association with periodontitis prevalence in a diverse group of Hispanics/Latinos.METHODS: Data came from 8675 lifetime nonsmokers in the 2008-2011 Hispanic Community Health Study/Study of Latinos. Exposure to ETS was self-report... | ['Adolescent', 'Adult', 'Aged', 'Female', 'Hispanic Americans', 'Humans', 'Male', 'Middle Aged', 'Periodontitis', 'Prevalence', 'Tobacco Smoke Pollution', 'United States'] | 27,978,596 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.686.754.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C07.465.714.533'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['D20.633.937.680', 'N06.850.460.100.5... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Allergic contact dermatitis to a photopolymerizable resin used in printing. | Organic photopolymerizable resins increasingly used in printing make it possible to produce flexible, lighter plates. A certain number of skin lesions and general symptoms appeared upon manipulation of plates made by the Letterflex process. In the workshop where this study was carried out, 12 out of 15 people suffered ... | ['3-Mercaptopropionic Acid', 'Animals', 'Dermatitis, Contact', 'Dermatitis, Occupational', 'Guinea Pigs', 'Hand Dermatoses', 'Humans', 'Polyenes', 'Printing', 'Resins, Plant', 'Skin Tests', 'Toluene 2,4-Diisocyanate'] | 201,427 | [['D02.241.081.751.080', 'D02.886.489.520'], ['B01.050'], ['C17.800.174.255', 'C17.800.815.255'], ['C17.800.174.255.700', 'C17.800.815.255.700', 'C24.270'], ['B01.050.150.900.649.313.992.550'], ['C17.800.338'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.326.271.665'], ['L01.737.787'], ['D05.750.078.840'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation. | F-actin polymerization following engagement of the T cell receptor (TCR) is dependent on WASP and is critical for T cell activation. The link between TCR and WASP is not fully understood. In resting cells, WASP exists in a complex with WIP, which inhibits its activation by Cdc42. We show that the adaptor protein CrkL b... | ['Actins', 'Animals', 'B-Lymphocytes', 'Carrier Proteins', 'Cell Line', 'Cytoskeletal Proteins', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Jurkat Cells', 'Kinetics', 'Mice', 'Mice, Knockout', 'Protein Kinase C', 'Protein Kinase C beta', 'Protein Transport', 'Proteins', 'Receptors, Antigen, T-Cell', 'T... | 12,504,004 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D12.776.157'], ['A11.251.210'], ['D12.776.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Indications for conservative management of acute scrotal pain in children. | Forty-three boys who presented with acute scrotal pain were studied retrospectively. Of these, 40 had torsion of scrotal contents. Torsion of testicular appendages, a self limiting condition, tended to present later than testicular torsion (P = 0.002). The testis was saved in all 11 cases of testicular torsion explored... | ['Adolescent', 'Child', 'Child, Preschool', 'Epididymitis', 'Humans', 'Male', 'Pain', 'Prospective Studies', 'Retrospective Studies', 'Scrotum', 'Spermatic Cord Torsion', 'Time Factors'] | 2,322,797 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['C12.294.199'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.318.372.500.500.500', 'E05.318.372.500.750... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Interpretation of high wedge pressure on exercise in patients with chronic obstructive pulmonary disease. | In a retrospective review of patients subjected to right heart catheterization, case records from 109 consecutive patients with chronic obstructive pulmonary disease (COPD) and wedge pressure > or =15 mm Hg on exercise were analyzed. Patients were separated into group 1, resting wedge pressure (P macro w) <15 mm Hg and... | ['Aged', 'Cardiac Catheterization', 'Diastole', 'Exercise Test', 'Female', 'Forced Expiratory Volume', 'Humans', 'Lung Diseases, Obstructive', 'Male', 'Middle Aged', 'Pulmonary Heart Disease', 'Pulmonary Wedge Pressure', 'Retrospective Studies', 'Ventricular Dysfunction, Left', 'Ventricular Function, Left', 'Vital Capa... | 11,474,159 | [['M01.060.116.100'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['G09.330.580.295', 'G11.427.494.554.250', 'G11.427.494.570.295'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.495'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Deaths averted by influenza vaccination in the U.S. during the seasons 2005/06 through 2013/14. | BACKGROUND: Excess mortality due to seasonal influenza is substantial, yet quantitative estimates of the benefit of annual vaccination programs on influenza-associated mortality are lacking.METHODS: We estimated the numbers of deaths averted by vaccination in four age groups (0.5 to 4, 5 to 19, 20 to 64 and ?65 yrs.) f... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Bayes Theorem', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Immunization Programs', 'Infant', 'Influenza Vaccines', 'Influenza, Human', 'Male', 'Middle Aged', 'Seasons', 'Time Factors', 'United States', 'Vaccination', 'Young Adult'] | 25,812,842 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.726.608'... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
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