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The fate of 14C derived from radioactively labelled dietary precursors in young rats of the Zucker strain (Fa/- and fa/fa). | The metabolic fate of 14C derived from radioactively labelled dietary precursors was determined in immature (18- and 25-day-old) lean and obese Zucker rats. This included measurement of 14C incorporated into body lipid, non-essential amino acids and expired CO2. Before weaning (18 days) there was no phenotypic differen... | ['Animals', 'Carbon Radioisotopes', 'Glucose', 'Lactates', 'Lactic Acid', 'Leucine', 'Obesity', 'Palmitic Acid', 'Palmitic Acids', 'Rats', 'Rats, Zucker', 'Valine'] | 3,741,393 | [['B01.050'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['D09.947.875.359.448'], ['D02.241.511.459'], ['D02.241.511.459.450'], ['D12.125.070.637', 'D12.125.142.441'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120.699.500'], ['D10.251.694.750'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increased responsivity of dentate granule cells during nictitating membrane response conditioning in rabbit. | We examined the responsivity of dentate gyrus granule cells to perforant path stimulation during classical conditioning of the rabbit nictitating membrane response. Dentate field potentials elicited by perforant path stimulation were recorded during training to test for changes in granule cell responsivity. Results sho... | ['Action Potentials', 'Animals', 'Brain Mapping', 'Conditioning, Classical', 'Conditioning, Eyelid', 'Hippocampus', 'Male', 'Neural Pathways', 'Nictitating Membrane', 'Physical Stimulation', 'Rabbits', 'Sound'] | 6,466,434 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.425.179.308'], ['F02.463.425.179.408'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['A08.612'], ['A13.660'], ['E05.723'], ['B01.050.150.900.649.313.9... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mercaptan-capturing properties of mushrooms. | Mercaptan-capturing properties of 33 kinds of mushrooms were measured. The mushrooms having a high capturing ability toward methyl mercaptan (MeSH) were Agaricus bisporus, A. campestris, Boletus fraternus, B. subvelutipes, Gyrodon lividus, Leccinum scabrum, Suillus grevillei, Morchella esculenta, Russula nigricans, Hyp... | ['Agaricales', 'Chromatography, High Pressure Liquid', 'Magnetic Resonance Spectroscopy', 'Species Specificity', 'Spectrophotometry, Ultraviolet', 'Sulfhydryl Compounds'] | 11,714,352 | [['B01.300.179.100'], ['E05.196.181.400.300'], ['E05.196.867.519'], ['G16.824'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['D02.886.489']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of variations in extracellular pH on spontaneous contractile activity and response to nerve stimulation in smooth muscle from rat urinary bladder. | The effects of variations in extracellular pH have been studied on rat detrusor muscle in vitro. At pH 7.4 a continuous low amplitude spontaneous contractile activity was found. At pH 6.75 the contractions became more regular with periods of relaxation between the contractions which had increased in amplitude. At pH 7.... | ['Acid-Base Equilibrium', 'Animals', 'Carbachol', 'Electric Stimulation', 'Female', 'Hydrogen-Ion Concentration', 'Membrane Potentials', 'Motor Neurons', 'Muscle Contraction', 'Muscle, Smooth', 'Neuromuscular Junction', 'Potassium Channels', 'Rats', 'Rats, Inbred Strains', 'Urinary Bladder'] | 2,320,972 | [['G02.111.007', 'G02.300.176', 'G03.030', 'G07.410.110', 'G09.188.050'], ['B01.050'], ['D02.092.877.883.333.115', 'D02.675.276.232.115'], ['E05.723.402'], ['G02.300'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['A08.675.655.500', 'A11.671.655.500'], ['G11.427.494'], ['A02.633.570', 'A10.690.467'], ['A0... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Leptomeningeal dissemination of ovarian carcinoma through a ventriculoperitoneal shunt. | BACKGROUND: Dissemination of ovarian cancer occurs mainly within the peritoneal cavity and central nervous system involvement (CNS) is encountered rarely. This report describes an unusual case with iatrogenic leptomeningeal metastasis from ovarian carcinoma.CASE: 36 year-old lady diagnosed with ovarian carcinoma develo... | ['Adult', 'Female', 'Humans', 'Hydrocephalus', 'Meningeal Neoplasms', 'Neoplasm Seeding', 'Ovarian Neoplasms', 'Ventriculoperitoneal Shunt'] | 17,961,641 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.602'], ['C04.588.614.250.580', 'C10.551.240.500'], ['C04.697.650.830', 'C23.550.727.650.830'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.630.705'], ['E04.035.188.850', 'E04.525.170.850']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Corynebacterium ulcerans in humans and cattle in North Devon. | A case of Corynebacterium ulcerans sore throat in a community that drank raw milk from its own farm led to the discovery of another symptomless human infection. Eight cows in the herd were found to be infected and the intermittent pattern of excretion was demonstrated in another cow followed through its lactation. Furt... | ['Animals', 'Cattle', 'Cattle Diseases', 'Child', 'Corynebacterium Infections', 'England', 'Female', 'Food Microbiology', 'Humans', 'Male', 'Milk', 'Pharyngitis'] | 6,707,468 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['M01.060.406'], ['C01.150.252.410.040.246'], ['Z01.542.363.300'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A... | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 |
Promoter hypermethylation in sentinel lymph nodes as a marker for breast cancer recurrence. | PURPOSE: Promoter methylation of tumor suppressor genes in histologically negative sentinel lymph nodes (HNSN) of early stage breast cancer patients has not been extensively studied. This study evaluates the methylation frequency and pattern in HNSN to determine if detection of hypermethylation of one or more genes is ... | ['Biomarkers, Tumor', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Carcinoma, Lobular', 'DNA Methylation', 'Female', 'Humans', 'Lymphatic Metastasis', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Polymerase Chain Reaction', 'Prognosis', 'Promoter Regions, Genetic', 'Prospective Studies', 'Sentinel Lymph Node Biop... | 18,404,369 | [['D23.101.140'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['C04.557.470.200.025.305', 'C04.557.470.615.305', 'C04.588.180.437', 'C17.800.090.500.437'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Expandable metallic endoprostheses for biliary obstruction. | Expandable metal stents (20 Gianturco Z-stents and 1 Strecker stent deployed through 8.5 F sheaths) were used with initial success for palliating bile duct obstruction in 10 patients, 8 with malignant and 2 with benign strictures. Short-term failure occurred in one patient after 2 weeks, one died of unrelated causes af... | ['Adult', 'Aged', 'Cholestasis', 'Female', 'Humans', 'Metals', 'Middle Aged', 'Prostheses and Implants', 'Stents'] | 8,489,838 | [['M01.060.116'], ['M01.060.116.100'], ['C06.130.120.135'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.552'], ['M01.060.116.630'], ['E07.695'], ['E07.695.750']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dynamic CT in pancreatic lymphoma. | We retrospectively reviewed the dynamic CT examinations of eight patients with pancreatic lymphoma. Four tumors were rounded masses with well-defined contours, four were more infiltrating lesions. The median cross-sectional diameter of the tumors was 6 cm (range 2.5-12 cm). At dynamic CT, the tumors were hypodense (n =... | ['Adipose Tissue', 'Adult', 'Aged', 'Constriction, Pathologic', 'Dilatation, Pathologic', 'Fascia', 'Female', 'Humans', 'Lymphoma, Non-Hodgkin', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Pancreatic Ducts', 'Pancreatic Neoplasms', 'Radiographic Image Enhancement', 'Splenic Vein', 'Tomography, X-Ray Computed'] | 8,419,447 | [['A10.165.114'], ['M01.060.116'], ['M01.060.116.100'], ['C23.300.287'], ['C23.300.325'], ['A02.340', 'A10.165.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480', 'C15.604.515.569.480', 'C20.683.515.761.480'], ['M01.060.116.630'], ['C04.697.645', 'C23.550.727.645'], ['A03.734.667'], ['C04.588.27... | ['Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
A "novel" surgical approach to ureteroileal anastomosis in patients with bricker urinary diversion. | We present a technique used in two patients with Bricker urinary diversion for the approach of ureteroileal anastomosis. The right lateral extraperitoneal approach provides fast access to the site, is virtually bloodless and appears to have no major complications. Although this method is extensively used by urologists,... | ['Aged', 'Anastomosis, Surgical', 'Carcinoma, Transitional Cell', 'Female', 'Humans', 'Ilium', 'Male', 'Ureter', 'Urinary Bladder Neoplasms', 'Urinary Diversion'] | 7,591,571 | [['M01.060.116.100'], ['E04.035'], ['C04.557.470.200.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.043.825.434'], ['A05.810.776'], ['C04.588.945.947.960', 'C12.758.820.968', 'C12.777.829.813', 'C13.351.937.820.945', 'C13.351.968.829.707'], ['E04.950.774.852']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Electron microscopic determination of phenoloxidase (EC 1.14.18.1) in eosinophilic granulocytes of the small intestine of white rats]. | It is shown that the light microscopic permanent detectable phenoloxidase activity, using dihydroxyphenylalanine as substrate, of the small intestine of white rats is localized in the most cases in eosinophilic granulocytes. The enzyme has been found as well in the cytoplasma as in the granules. The enzyme proof trigge... | ['Animals', 'Catechol Oxidase', 'Cytoplasmic Granules', 'Eosinophils', 'Intestine, Small', 'Mast Cells', 'Microscopy, Electron', 'Monophenol Monooxygenase', 'Rats'] | 2,414,184 | [['B01.050'], ['D08.811.682.690.708.125'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['A03.556.124.684'], ['A11.329.427', 'A15.382.652'], ['E01.370.350.515.402', 'E05.595.402'], ['D08.811.682.690.708.125.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Top-down inputs from the olfactory cortex in the postprandial period promote elimination of granule cells in the olfactory bulb. | Elimination of granule cells (GCs) in the olfactory bulb (OB) is not a continual event but is promoted during a short time window in the postprandial period, typically with postprandial sleep. However, the neuronal mechanisms for the enhanced GC elimination during the postprandial period are not understood. Here, we ad... | ['Animals', 'Apoptosis', 'Axons', 'Catheters, Indwelling', 'Cell Count', 'Electric Stimulation', 'Electrodes, Implanted', 'Electroencephalography', 'GABA-A Receptor Agonists', 'Immunohistochemistry', 'Male', 'Mice, Inbred C57BL', 'Muscimol', 'Neurons', 'Olfactory Bulb', 'Olfactory Cortex', 'Olfactory Pathways', 'Postpr... | 25,041,475 | [['B01.050'], ['G04.146.954.035'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['E07.132.500'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['E05.723.402'], ['E07.305.250.319', 'E07.695.202'], ['E01.370.376.300', 'E01.370.405.245'], ['D27.505.519.625.240.200.500',... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Primacy of surgery for colorectal cancer. | BACKGROUND: The optimal technique for curative resection of colonic cancer includes high ligation of the mesenteric vessels, wide excision of the colonic mesentery and prevention of tumour cell spillage. This article reports results from the authors' institution for patients in whom complete mesocolic excision was perf... | ['Adult', 'Aged', 'Aged, 80 and over', 'Colectomy', 'Colorectal Neoplasms', 'Female', 'Follow-Up Studies', 'Humans', 'Laparoscopy', 'Male', 'Middle Aged', 'Morbidity', 'Postoperative Complications', 'Retrospective Studies', 'Survival Rate', 'Time Factors', 'United States', 'Young Adult'] | 25,832,316 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.210.219'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cervical myelopathy in an adolescent with Hallervorden-Spatz disease. | Hallervorden-Spatz disease is a rare neurodegenerative disorder characterized by progressive dystonia, rigidity, and dementia. In these patients, chronic repeated dystonic movements, especially of the head and neck, can lead to excessive stress on the cervical spine, resulting in early degenerative changes and myelopat... | ['Adult', 'Cervical Vertebrae', 'Humans', 'Male', 'Pantothenate Kinase-Associated Neurodegeneration', 'Spinal Cord Diseases'] | 14,643,398 | [['M01.060.116'], ['A02.835.232.834.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.079.800', 'C10.228.140.744.320', 'C10.228.662.575', 'C10.574.500.700', 'C16.320.400.650'], ['C10.228.854']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Combined effect of solvent content, temperature and pH on the chromatographic behaviour of ionisable compounds. | The organic solvent content and the pH in the mobile phase are the usual main factors in reversed-phase liquid chromatographic separations, owing to their strong effects on retention and/or selectivity. Temperature is often neglected. However, even in cases where the impact of this factor on selectivity is minor, the r... | ['Adrenergic beta-Antagonists', 'Chromatography, Liquid', 'Diuretics', 'Hydrogen-Ion Concentration', 'Ions', 'Solvents', 'Temperature'] | 17,585,924 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['E05.196.181.400'], ['D27.505.696.560.500'], ['G02.300'], ['D01.248.497'], ['D27.720.844'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Development of systems for targeting the regional lymph nodes for diagnostic imaging: in vivo behaviour of colloidal PEG-coated magnetite nanospheres in the rat following interstitial administration. | PURPOSE: Nanoparticles can be utilised for targeting drugs to the regional lymph nodes or as diagnostic agents. The surface modification of magnetite nanospheres with poly(ethylene glycol) (PEG) has been assessed by in vitro characterisation and in vivo studies following subcutaneous administration to the rat.METHODS: ... | ['Animals', 'Chemical Phenomena', 'Chemistry, Physical', 'Colloids', 'Contrast Media', 'Dextrans', 'Excipients', 'Iron', 'Iron Radioisotopes', 'Lymph Nodes', 'Magnetic Resonance Imaging', 'Male', 'Particle Size', 'Polyethylene Glycols', 'Rats', 'Rats, Wistar', 'Silanes', 'Surface Properties', 'Tissue Distribution'] | 11,465,419 | [['B01.050'], ['G02'], ['H01.181.529'], ['D20.280', 'D26.255.165'], ['D27.505.259.500', 'D27.720.259'], ['D05.750.078.562.272', 'D09.698.365.272'], ['D26.650.700.419', 'D27.720.744.770.419'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D01.268.556.412.500.498', 'D01.268.956.287.500.498', 'D01.496.473.4... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Effect of kainic acid and pentetrazole administration on the activity of nitric oxide synthase in the mouse brain. | The present study examined ex vivo effect of kainic acid and pentetrazole administration on the activity of nitric oxide synthase (NOS) in the mouse brain. NOS activity was assayed by measuring the formation of [3H] citrulline from [3H]arginine in the homogenates of mouse hippocampus, neocortex and cerebellum. The high... | ['Animals', 'Brain', 'Convulsants', 'Enzyme Activation', 'Excitatory Amino Acid Agonists', 'Kainic Acid', 'Male', 'Mice', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type I', 'Pentylenetetrazole', 'omega-N-Methylarginine'] | 9,861,634 | [['B01.050'], ['A08.186.211'], ['D27.505.696.282.224', 'D27.505.954.427.220.224'], ['G02.111.263', 'G03.328'], ['D27.505.519.625.190.200', 'D27.505.696.577.190.200'], ['D03.383.773.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['D08.811.682.664.500.772'], ['D08.811.682.664.500.772.249'], ['D03.383.066.600'], ['D1... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunological characterization of homosexual males. | To help clarify the nature and pathogenesis of the syndrome of severely opportunistic infection associated with immune deficiency in young homosexual males, we investigated the immunological characteristics of a group of 33 young homosexual men. These young men all had the prodrome to the syndrome which included a hist... | ['Adult', 'Antibodies, Monoclonal', 'Antibody-Dependent Cell Cytotoxicity', 'Antigen-Antibody Complex', 'Antigens, Surface', 'B-Lymphocytes', 'Homosexuality', 'Humans', 'Immunity', 'Immunoglobulins', 'Killer Cells, Natural', 'Leukocytes', 'Lymphocyte Activation', 'Male', 'Muramidase', 'Rosette Formation', 'T-Lymphocyte... | 6,600,216 | [['M01.060.116'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.287.070'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['D23.050.301'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Decreasing carotid endarterectomy length of stay at a university hospital. | In 1995, a clinical pathway for carotid endarterectomy patients was instituted at the authors' institution. The effect of this program on length of stay and patient outcomes was investigated. Records of 152 consecutive carotid endarterectomies performed by a single surgeon over a 45-month period with identical techniqu... | ['Adult', 'Aged', 'Aged, 80 and over', 'Angiography', 'Blood Vessel Prosthesis Implantation', 'Cause of Death', 'Cost Savings', 'Critical Pathways', 'Endarterectomy, Carotid', 'Female', 'Hospital Mortality', 'Hospitals, University', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Outcome and Process Assessment, Hea... | 10,386,745 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350.700.060', 'E01.370.370.050'], ['E04.100.814.868.500', 'E04.650.200'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['N03.219.151.160.200'], ['N04.590.233.624.625', 'N04.590.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Successful resuscitation by extracorporeal circulation after fibrillation during vascular reconstruction]. | Extracorporeal circulation (EC) for reanimation of refractory cardiac fibrillation during vascular surgery. The fibrillation occurred shortly after induction of anesthesia but no specific medication could be incriminated. Postoperative morbidity was significant but the patient eventually made a successful recovery. Use... | ['Extracorporeal Circulation', 'Humans', 'Male', 'Middle Aged', 'Resuscitation', 'Vascular Surgical Procedures', 'Ventricular Fibrillation'] | 3,223,186 | [['E04.292'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.365.647'], ['E04.100.814'], ['C14.280.067.922', 'C23.550.073.922']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Visualization of HIV-1 Gag Binding to Giant Unilamellar Vesicle (GUV) Membranes. | The structural protein of HIV-1, Pr55(Gag) (or Gag), binds to the plasma membrane in cells during the virus assembly process. Membrane binding of Gag is an essential step for virus particle formation, since a defect in Gag membrane binding results in severe impairment of viral particle production. To gain mechanistic d... | ['Bacterial Proteins', 'Cell Membrane', 'Gene Products, gag', 'HIV-1', 'Luminescent Proteins', 'Microscopy, Fluorescence', 'Protein Binding', 'Unilamellar Liposomes', 'Virus Assembly'] | 27,500,610 | [['D12.776.097'], ['A11.284.149'], ['D12.776.775.330', 'D12.776.964.775.350', 'D12.776.964.970.600.850.350'], ['B04.820.650.589.650.350.400'], ['D12.776.532'], ['E01.370.350.515.458', 'E05.595.458'], ['G02.111.679', 'G03.808'], ['D25.479.517.500', 'J01.637.051.479.517.500', 'J01.637.087.500.517.500'], ['G06.920.925.950... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Characterization of epitope specificities of reference antibodies used for the quantification of the birch pollen allergen Bet v 1. | BACKGROUND: Accurate allergen quantification is needed to document the consistency of allergen extracts used for immunotherapy. Herein, we characterize the epitope specificities of two monoclonal antibodies used in an ELISA for the quantification of the major birch pollen allergen Bet v 1, established as a reference by... | ['Allergens', 'Antibodies, Monoclonal', 'Antibody Specificity', 'Antigens, Plant', 'Desensitization, Immunologic', 'Epitope Mapping', 'Humans', 'Protein Isoforms'] | 29,171,882 | [['D23.050.063'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.100'], ['D23.050.291'], ['E02.095.465.425.450.310', 'E05.478.610.310'], ['E05.478.274', 'E05.601.690.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.800']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A practical method to analyze the phospholipids in the amniotic fluid using HPTLC. | An operative method using HPTLC which makes possible the determination of nine phospholipids in the amniotic fluid individually is described: lysophosphatidylcholine, sphingomyelin, phosphatidylcholine, phosphatidylinositol, phosphatidylserine, phosphatidylethanolamine, phosphatidylglycerol, phosphatidic acid and cardi... | ['Amniotic Fluid', 'Chromatography, Thin Layer', 'Fetal Organ Maturity', 'Humidity', 'Lung', 'Phosphatidic Acids', 'Sphingomyelins', 'Staining and Labeling'] | 2,428,083 | [['A12.098', 'A16.378.149'], ['E05.196.181.400.537'], ['G07.345.500.325.235.750', 'G07.345.500.325.377.249', 'G08.686.784.170.157.750'], ['G16.500.275.063.725.310', 'G16.500.750.775.310', 'N06.230.150.372', 'N06.230.300.100.725.310'], ['A04.411'], ['D10.570.755.375.760'], ['D09.400.410.420.525.870', 'D10.390.470.675.87... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Selective quantification of the cardiac sympathetic and parasympathetic nervous systems by multisignal analysis of cardiorespiratory variability. | Heart rate (HR) power spectral indexes are limited as measures of the cardiac autonomic nervous systems (CANS) in that they neither offer an effective marker of the beta-sympathetic nervous system (SNS) due to its overlap with the parasympathetic nervous system (PNS) in the low-frequency (LF) band nor afford specific m... | ['Adrenergic beta-Antagonists', 'Adult', 'Atropine', 'Blood Pressure', 'Cardiovascular System', 'Heart Rate', 'Humans', 'Lung Volume Measurements', 'Male', 'Models, Cardiovascular', 'Muscarinic Antagonists', 'Parasympathetic Nervous System', 'Posture', 'Propranolol', 'Reproducibility of Results', 'Signal Processing, Co... | 17,993,596 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A07'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B0... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[The diagnosis and treatment of acute pulmonary circulatory disorders after resection for tuberculosis]. | The authors analyzed postoperative complications after 4174 pulmonectomies for tuberculosis in the period of 1982-2004. The verified cases of acute venous circulatory disorders in the remnants of the lung after partial resections were observed in 12 (0.3%) patients. The main causes of hemorrhagic infarct of the part of... | ['Adult', 'Hemodynamics', 'Humans', 'Lung', 'Male', 'Mycobacterium tuberculosis', 'Postoperative Complications', 'Tuberculosis, Pulmonary', 'Venous Insufficiency'] | 16,405,089 | [['M01.060.116'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['C23.550.767'], ['C01.150.252.410.040.552.846.899', 'C01.748.939', 'C08.381.922', 'C08.730.939'], ['C14.907.952']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Identification of a heparin-binding domain in the distal carboxyl-terminal region of lipoprotein lipase by site-directed mutagenesis. | The interaction of lipoprotein lipase (LPL) with heparan sulfate proteoglycans plays an important role in the metabolism and catalytic function of the enzyme. We have used site-directed mutagenesis to replace the basic residues contained in a discontinuous charge cluster (residues Lys 321, Arg 405, Arg 407, Lys 409, Ly... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Binding Sites', 'Birds', 'CHO Cells', 'Chromatography, Affinity', 'Cricetinae', 'DNA Primers', 'Heparin', 'Lipoprotein Lipase', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Point Mutation', 'Recombinant Proteins', 'Transfection'] | 9,643,364 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['B01.050.150.900.248'], ['A11.251.210.200', 'A11.436.155'], ['E05.196.181.400.170'], ['B01.050.150.900.649.313.992.635.075.250'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.22... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Comparison of 131I-metaiodobenzylguanidine scintigraphy with urinary and plasma catecholamine determinations in the diagnosis of pheochromocytoma. | In a retrospective study of 31 patients with suspected pheochromocytoma we examined the preoperative results of 131I-metaiodobenzylguanidine (131-I-MIBG) scintigraphy and a fluorimetric urine catecholamine determination test. An additional radioenzymatic plasma catecholamine determination test was performed in 25 patie... | ['3-Iodobenzylguanidine', 'Adrenal Gland Neoplasms', 'Adult', 'Aged', 'Catecholamines', 'Female', 'Humans', 'Iodobenzenes', 'Male', 'Middle Aged', 'Pheochromocytoma', 'Radionuclide Imaging', 'Retrospective Studies'] | 4,032,986 | [['D02.078.370.510', 'D02.455.426.559.389.454.300', 'D02.455.526.581.496.300'], ['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['M01.060.116'], ['M01.060.116.100'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.389.454', 'D02.455.526.581.496']... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Deoxyribonucleoside kinases belonging to the thymidine kinase 2 (TK2)-like group vary significantly in substrate specificity, kinetics and feed-back regulation. | In eukaryotic cells deoxyribonucleoside kinases belonging to three phylogenetic sub-families have been found: (i) thymidine kinase 1 (TK1)-like enzymes, which are strictly pyrimidine deoxyribonucleoside-specific kinases; (ii) TK2-like enzymes, which include pyrimidine deoxyribonucleoside kinases and a single multisubst... | ['Amino Acid Sequence', 'Animals', 'Bombyx', 'Chickens', 'Chromatography, Gel', 'Databases, Genetic', 'Deoxycytidine', 'Drosophila melanogaster', 'Feedback, Physiological', 'Humans', 'Inhibitory Concentration 50', 'Kinetics', 'Mice', 'Models, Biological', 'Models, Molecular', 'Molecular Sequence Data', 'Phosphotransfer... | 11,812,127 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.500.131.617.720.500.500.937.650.100'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.196.181.400.250'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['D03.383.742.680.245.500', 'D13.570.230.329', 'D13.570.685.245.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Hepatitis B virus X protein upregulates DNA methyltransferase 3A/3B and enhances SOCS-1CpG island methylation. | The aim of the present study was to investigate the effect of hepatitis B virus X protein (HBx) on the expression of DNA methyltransferase (DNMT)3A/3B and suppressors of cytokine signaling‑1 (SOCS‑1), as well as promoter CpG island methylation of the SOCS‑1 gene. Stable hepatocyte cell lines expressing the HBx gene (pc... | ['Blotting, Western', 'Cell Line', 'CpG Islands', 'DNA (Cytosine-5-)-Methyltransferases', 'DNA Methylation', 'Humans', 'Immunohistochemistry', 'RNA, Messenger', 'Real-Time Polymerase Chain Reaction', 'Suppressor of Cytokine Signaling 1 Protein', 'Suppressor of Cytokine Signaling Proteins', 'Trans-Activators', 'Transfec... | 26,573,490 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['D08.811.913.555.500.350.100.500'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['B01.050.150.900.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Differential involvement of the anterior cingulate and primary sensorimotor cortices in sensory and affective functions of pain. | The present study examined the role of neurons in different pain-related functions of the anterior cingulate cortex (ACC) and primary sensorimotor cortex (SmI) by assessing their abilities to code different levels of noxious heat and activity changes evoked by classical fear conditioning involving electric shocks. Mult... | ['Action Potentials', 'Affect', 'Analysis of Variance', 'Animals', 'Behavior, Animal', 'Biophysics', 'Cerebral Cortex', 'Conditioning, Psychological', 'Electroshock', 'Fear', 'Female', 'Gyrus Cinguli', 'Lasers', 'Neural Inhibition', 'Neurons', 'Pain', 'Rats', 'Rats, Long-Evans', 'Reaction Time', 'Reflex, Startle', 'Sen... | 19,091,928 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['F01.470.047'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['F01.145.113'], ['H01.158.344', 'H01.671.100'], ['A08.186.211.200.885.287.500'], ['F02.463.425.179'], ['E05.723.402.403', 'F04.669.224'], ['F01.470.361'], ['A08.186.2... | ['Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
A comparison of three different guidelines for osteoporosis treatment in patients with rheumatoid arthritis in Korea. | BACKGROUND/AIMS: Osteoporotic fractures are an important comorbidity with rheumatoid arthritis (RA). We determined the overall fracture risk as assessed by the World Health Organization (WHO)'s FRAX® tool in Korean patients with seropositive RA. Additionally, we compared treatment eligibility according to the criteria ... | ['Aged', 'Arthritis, Rheumatoid', 'Bone Density', 'Cross-Sectional Studies', 'Female', 'Hip Fractures', 'Humans', 'Korea', 'Male', 'Middle Aged', 'Osteoporosis', 'Osteoporotic Fractures', 'Practice Guidelines as Topic', 'Prevalence'] | 21,179,283 | [['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['G11.427.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.557', 'Z01.586... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Navigation Guidance During Free Flap Mandibular Reconstruction: A Cadaveric Trial. | Importance: Segmental mandibulectomy for tumors that distort the buccal surface of the mandible present a reconstructive challenge.Objective: To determine whether mandible alignment after navigation-guided mandible reconstruction is better than alignment after non-template-assisted freehand reconstruction and as good a... | ['Cadaver', 'Free Tissue Flaps', 'Humans', 'Mandibular Reconstruction', 'Surgery, Computer-Assisted'] | 27,893,003 | [['C23.550.260.224'], ['A10.850.710.500', 'E07.862.710.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E06.645.562.500'], ['E04.749']] | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of pronase E in ligand binding to Fc receptors in the reaction of cytotoxicity mediated by bovine blood neutrophils. | We studied the effects of pronase E on IgG binding to Fcg receptors on bovine blood neutrophils and kinetic parameters of this reaction (association constant and number of binding sites on neutrophils). During in vitro modeling of the cell immune response, we evaluated cytotoxic activity of effector neutrophils against... | ['Animals', 'Cattle', 'Cytotoxicity, Immunologic', 'Kinetics', 'Ligands', 'Neutrophils', 'Pronase', 'Protein Binding', 'Receptors, Fc'] | 12,124,644 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G12.287'], ['G01.374.661', 'G02.111.490'], ['D27.720.470.480'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.689'], ['D08.811.277.656.300.480.680', 'D08.811.277.656.300.760.638', 'D08.811... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hepatico-jejuno-duodenostomy reconstruction following excision of choledochal cysts in children. | Ten children with choledochal cysts were treated at Children's Memorial Hospital in Chicago between 1979 and 1980 and at Henrietta Egleston Hospital for Children or Grady Memorial Hospital in Atlanta between 1980 and 1987. Age at the time of operation ranged from one to 46 months. There were eight girls and two boys wi... | ['Child, Preschool', 'Common Bile Duct Diseases', 'Cysts', 'Duodenum', 'Female', 'Follow-Up Studies', 'Hepatic Duct, Common', 'Humans', 'Infant', 'Jejunum', 'Male'] | 2,913,904 | [['M01.060.406.448'], ['C06.130.120.250'], ['C04.182', 'C23.300.306'], ['A03.556.124.684.124', 'A03.556.875.249'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A03.159.183.079.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A03.556.124.684.500',... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Resonance Raman characterization of biotin sulfoxide reductase. Comparing oxomolybdenum enzymes in the ME(2)SO reductase family. | Resonance Raman spectroscopy has been used to define active site structures for oxidized Mo(VI) and reduced Mo(IV) forms of recombinant Rhodobacter sphaeroides biotin sulfoxide reductase expressed in Escherichia coli. On the basis of (18)O/(16)O labeling studies involving water and the alternative substrate dimethyl su... | ['Catalysis', 'Iron-Sulfur Proteins', 'Oxidoreductases', 'Spectrum Analysis, Raman', 'Thermodynamics'] | 10,702,237 | [['G02.130'], ['D12.776.157.427.374.375', 'D12.776.556.579.374.375'], ['D08.811.682'], ['E05.196.822.860', 'E05.196.867.890'], ['G01.906']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antileucoprotease in the developing fetal lung. | The distribution of antileucoprotease in the lungs of 25 fetuses of 9-40 weeks' gestation was studied with monoclonal antibodies and an indirect immunoperoxidase technique. Antileucoprotease was detected from 16 weeks in submucosal glands and collecting ducts in the trachea and main and lobar bronchi: it was also found... | ['Cell Differentiation', 'Embryonic and Fetal Development', 'Fetus', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Lung', 'Protease Inhibitors', 'Proteinase Inhibitory Proteins, Secretory', 'Proteins'] | 3,206,386 | [['G04.152'], ['G07.345.500.325', 'G08.686.784.170'], ['A16.378'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['A04.411'], ['D27.505.519.389.745'], ['D12.644.822', 'D12.776.645'], ['D12.776']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Legal and ethical framework for global health information and biospecimen exchange - an international perspective. | BACKGROUND: The progress of electronic health technologies and biobanks holds enormous promise for efficient research. Evidence shows that studies based on sharing and secondary use of data/samples have the potential to significantly advance medical knowledge. However, sharing of such resources for international collab... | ['Electronic Health Records', 'Global Health', 'Humans', 'Information Dissemination', 'International Cooperation', 'Internationality', 'Ownership', 'Tissue Banks'] | 31,964,390 | [['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.530.250', 'N06.850.520.308.940.968.625.250'], ['H02.403.371', 'N01.400.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.143.443'], ['I01.615.500'], ['I01.615'], ['I01.880.604.583.594', 'N04.452.633'], ['N02.278.065.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Pharmacological manipulation of anxiety and male rat sexual behavior. | Several anxiolytic/anxiogenic treatments were evaluated on male rat sexual behavior. The anxiolytic drug diazepam (1.0 mg/kg) inhibited copulatory behavior as indicated by an increase in the number of mounts preceding ejaculation, prolongation of the ejaculation latency and the postejaculatory interval. These changes w... | ['Animals', 'Anxiety', 'Carbolines', 'Copulation', 'Diazepam', 'Flumazenil', 'Male', 'Psychomotor Performance', 'Rats', 'Rats, Inbred Strains'] | 2,107,555 | [['B01.050'], ['F01.470.132'], ['D03.383.725.150', 'D03.633.100.473.155', 'D03.633.300.154'], ['F01.145.113.252.748.200'], ['D03.633.100.079.080.070.216'], ['D03.633.100.079.080.070.305'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.90... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Liver-specific activities of FGF19 require Klotho beta. | Hepatocyte function is regulated by members of the fibroblast growth factor (FGF) family of proteins, but little is known about the specific molecular mechanisms of this endocrine pathway. FGF19 regulates bile acid homeostasis and gall bladder filling; FGF19 binds only to FGF receptor 4 (FGFR4), but its liver-specific ... | ['Animals', 'Extracellular Signal-Regulated MAP Kinases', 'Female', 'Fibroblast Growth Factors', 'Gene Expression Regulation', 'Glucuronidase', 'Heparin', 'Humans', 'Liver', 'Mice', 'Organ Specificity', 'Phosphorylation', 'Proto-Oncogene Proteins c-fos', 'Receptor, Fibroblast Growth Factor, Type 4', 'Signal Transductio... | 17,627,937 | [['B01.050'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.169'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['G05.308'], ['D08.811.277.450.426'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lack of lymphangiogenesis during breast carcinogenesis. | BACKGROUND: Recent evidence suggests that functional intratumorous lymph vessels may be absent from some human cancers. This could result from either the failure of tumours to induce lymphangiogenesis, or the collapse of lymph vessels, caused by high interstitial tumour pressure.METHODS: To differentiate between these ... | ['Breast', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Carcinoma, Intraductal, Noninfiltrating', 'Cell Transformation, Neoplastic', 'Disease Progression', 'Female', 'Humans', 'Hyperplasia', 'Lymphatic System', 'Neovascularization, Pathologic', 'Precancerous Conditions'] | 15,220,369 | [['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['C04.557.470.200.025.275', 'C04.557.470.200.240.187.250', 'C04.557.470.615.275'], ['C04.697.098.500', 'C23.550.727.098.500'], ['C23.550.291.656'], ['B01.050.150.900.64... | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition of HIV Fusion by Small Molecule Agonists through Efficacy-Engineering of CXCR4. | CXC chemokine receptor 4 (CXCR4) is involved in multiple physiological and pathological processes, notably as a coreceptor for human immunodeficiency virus (HIV) cell entry. Its broad expression pattern and vital biological importance make CXCR4 a troublesome drug target, as disruption of the interaction with its endog... | ['Anti-HIV Agents', 'HIV Fusion Inhibitors', 'HIV-1', 'Humans', 'Protein Engineering', 'Receptors, CXCR4'] | 29,461,034 | [['D27.505.954.122.388.077.088'], ['D27.505.519.957.500', 'D27.505.954.122.388.077.088.209', 'D27.505.954.122.388.538.500'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.420.601'], ['D12.776.543.750.695.160.500.400', 'D12.776.543.750.705.852.125.500.400', 'D12.776.543.750.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of type of procedure and surgeon on EuroSCORE operative risk validation. | OBJECTIVE: EuroSCORE has been used in cardiac surgery operative risk assessment, despite important variables were not included. The objective of this study was to validate EuroSCORE on mortality prediction in a Brazilian cardiovascular surgery center, defining the influence of type of procedure and surgical team.METHOD... | ['Adult', 'Aged', 'Brazil', 'Cardiovascular Surgical Procedures', 'Female', 'Hospital Mortality', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Patient Care Team', 'Reproducibility of Results', 'Risk Assessment', 'Risk Factors', 'Sensitivity and Specificity', 'Surgeons', 'Time Factors'] | 25,140,461 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.107.757.176'], ['E04.100'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.8... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Age and sex distribution of intestinal type and diffuse gastric carcinoma. | A twelve-year series of 375 patients with gastric carcinoma has been studied. Primary tumours were classified as intestinal type (58%) or diffuse (26%), whereas 16% were unclassifiable. The relative age and sex incidence rates of intestinal type and diffuse gastric carcinoma were estimated using the age and sex distrib... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Carcinoma', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Norway', 'Sex Factors', 'Stomach Neoplasms'] | 1,993,119 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.116.630'], ['Z01.542.8... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
NMDA and non-NMDA receptors mediate taste afferent inputs to cortical taste neurons in rats. | Two main subclasses of ionotropic receptors for excitatory amino acids (EAAs), N-methyl-D-aspartate (NMDA) receptors and non-NMDA receptors, are involved in neurotransmission in the cortex of mammals. To examine whether EAAs are transmitters at the cortical taste area (CTA) in rats and to elucidate which types of the t... | ['2-Amino-5-phosphonovalerate', '6-Cyano-7-nitroquinoxaline-2,3-dione', 'Animals', 'Cerebral Cortex', 'Electrophysiology', 'Excitatory Amino Acid Antagonists', 'Kainic Acid', 'N-Methylaspartate', 'Neurons', 'Neurons, Afferent', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Glutamate', 'Receptors, N-Methyl-D-Aspartate', '... | 8,983,983 | [['D12.125.070.950.100', 'D12.125.740.025'], ['D03.633.100.857.160'], ['B01.050'], ['A08.186.211.200.885.287.500'], ['H01.158.344.528', 'H01.158.782.236'], ['D27.505.519.625.190.300', 'D27.505.696.577.190.300'], ['D03.383.773.400'], ['D12.125.067.500.400', 'D12.125.119.170.400'], ['A08.675', 'A11.671'], ['A08.675.650',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Sulphonamide-based bombesin prodrug analogues for glutathione transferase, useful in targeted cancer chemotherapy. | Glutathione transferases (GSTs) are enzymes involved in cellular detoxification by catalysing the nucleophilic attack of glutathione (GSH) on the electrophilic centre of a number of toxic compounds and xenobiotics, including certain chemotherapeutic drugs. The encountered chemotherapeutic resistant of tumour cells, thu... | ['Antineoplastic Agents', 'Bombesin', 'Glutathione Transferase', 'Humans', 'Prodrugs', 'Sulfonamides'] | 19,019,494 | [['D27.505.954.248'], ['D06.472.699.100', 'D12.644.400.085', 'D12.644.548.100', 'D12.776.631.650.085', 'D20.888.033.137', 'D23.946.833.033.137'], ['D08.811.913.225.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.675'], ['D02.065.884', 'D02.886.590.700']] | ['Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Hin invertasome: protein-mediated joining of distant recombination sites at the enhancer. | The Hin protein binds to two cis-acting recombination sites and catalyzes a site-specific DNA inversion reaction that regulates the expression of flagellin genes in Salmonella. In addition to the Hin protein and the two recombination sites that flank the invertible segment, a third cis-acting recombinational enhancer s... | ['Bacterial Proteins', 'Carrier Proteins', 'Chromosome Inversion', 'DNA, Bacterial', 'DNA, Superhelical', 'DNA-Binding Proteins', 'Deoxyribonucleoproteins', 'Enhancer Elements, Genetic', 'Factor For Inversion Stimulation Protein', 'Flagellin', 'Genes, Bacterial', 'Integration Host Factors', 'Models, Genetic', 'Nucleic ... | 2,166,334 | [['D12.776.097'], ['D12.776.157'], ['C23.550.210.190', 'G05.365.590.175.190', 'G05.365.590.770.500', 'G05.558.805.500'], ['D13.444.308.212'], ['D13.444.308.283.250', 'G02.111.570.820.486.212.250', 'G05.360.580.156.250'], ['D12.776.260'], ['D12.776.664.275'], ['G02.111.570.080.689.330', 'G05.360.080.689.330', 'G05.360.3... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Proteomics of Naja kaouthia venom from North East India and assessment of Indian polyvalent antivenom by third generation antivenomics. | In the present study, venom composition, toxic effects, and immunological characteristics of Naja kaouthia venom from North East India has been studied. Using RP-HPLC, venom components were separated and proteins in the fractions were identified using ESI-LC MS/MS. Proteins identified belong to 9 different snake venom ... | ['Animals', 'Antivenins', 'Elapid Venoms', 'Goats', 'India', 'Mice', 'Naja naja', 'Proteome', 'Proteomics', 'RAW 264.7 Cells'] | 31,344,496 | [['B01.050'], ['D12.776.124.486.485.114.573.601.138', 'D12.776.124.790.651.114.573.601.138', 'D12.776.377.715.548.114.573.601.138', 'D20.215.401.601.163'], ['D20.888.850.325', 'D23.946.833.850.325'], ['B01.050.150.900.649.313.500.380.513'], ['Z01.252.245.393'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
The practice of nurse-midwifery in the era of managed care: reports from the field. | OBJECTIVE: The purpose of this paper is to describe the reports of certified nurse-midwives (CNMs) about how changes in the financing and organization of health care in the late 1990s influenced their ability to serve vulnerable populations and provide a woman-centered, prevention-oriented midwifery model of care.METHO... | ['Attitude of Health Personnel', 'Comprehensive Health Care', 'Female', 'Health Care Surveys', 'Health Services Accessibility', 'Humans', 'Managed Care Programs', 'Maternal Health Services', 'Nurse Midwives', 'Patient-Centered Care', 'Pregnancy', 'Professional Practice', 'Quality of Health Care', 'Surveys and Questionn... | 12,092,981 | [['F01.100.050', 'N05.300.100'], ['N04.590.233'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.800', 'N04.590.374.410'], ['N02.421.143.620', 'N02... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Lexical tone identification and consonant recognition in acoustic simulations of cochlear implants. | CONCLUSION: Cochlear implant (CI) recipients' performance of lexical tone identification and consonant recognition can be enhanced by providing greater spectral details.OBJECTIVE: To evaluate the effects of increasing the number of total spectral channels on the lexical tone identification and consonant recognition by ... | ['Adult', 'Asian Continental Ancestry Group', 'Cochlear Implants', 'Humans', 'Models, Biological', 'Pattern Recognition, Physiological', 'Phonetics', 'Pitch Discrimination', 'Semantics', 'Signal Processing, Computer-Assisted', 'Speech Acoustics', 'Speech Perception'] | 19,444,660 | [['M01.060.116'], ['M01.686.508.200'], ['E07.305.250.319.381.500.500', 'E07.695.150', 'E07.695.202.381.500.500', 'E07.814.458.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['F02.463.593.524'], ['L01.559.598.518'], ['F02.463.593.071.700.408', 'G07.888.125.700.408'], ['L01.559.598.745'], ['L01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Constitutive expression of Wnt/â‑catenin target genes promotes proliferation and invasion of liver cancer stem cells. | Wnt/â‑catenin is an important signaling pathways involved in the tumorgenesis, progression and maintenance of cancer stem cells (CSCs). In the present study, the role of Wnt/â‑catenin signaling in CSC‑mediated tumorigenesis and invasion in liver CSCs was investigated. A small population of cancer stem‑like side populat... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Animals', 'Antineoplastic Agents', 'Cell Movement', 'Cell Proliferation', 'Cyclin D1', 'Female', 'Humans', 'Liver Neoplasms', 'Male', 'Mice', 'Mice, Inbred NOD', 'Mice, SCID', 'Middle Aged', 'Neoplastic Stem Cells', 'Side-Population Cells', 'Tumor Cells, Cult... | 26,956,539 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['B01.050'], ['D27.505.954.248'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Designing anti-diabetic â-cells microcapsules using polystyrenic sulfonate, polyallylamine, and a tertiary bile acid: Morphology, bioenergetics, and cytokine analysis. | PURPOSE: Recently sodium alginate (SA)-poly-l-ornithine (PLO) microcapsules containing pancreatic â-cells that showed good morphology but low cell viability (<27%) was designed. In this study, two new polyelectrolytes, polystyrenic sulfonate (PSS; at 1%) and polyallylamine (PAA; at 2%) were incorporated into a microenc... | ['Animals', 'Bile Acids and Salts', 'Cell Survival', 'Cells, Cultured', 'Cytokines', 'Drug Compounding', 'Drug Design', 'Energy Metabolism', 'Hypoglycemic Agents', 'Insulin-Secreting Cells', 'Mice', 'Polyamines', 'Polystyrenes', 'Sulfonic Acids'] | 26,748,789 | [['B01.050'], ['D04.210.500.105'], ['G04.346'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['E05.916.270'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['G03.295'], ['D27.505.696.422'], ['A03.734.414.131', 'A06.300.414.087', 'A06.390.131', 'A11.382.625.092', 'A11.436.294.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
In vivo imaging of a stable paramagnetic probe by pulsed-radiofrequency electron paramagnetic resonance spectroscopy. | Imaging of free radicals by electron paramagnetic resonance (EPR) spectroscopy using time domain acquisition as in nuclear magnetic resonance (NMR) has not been attempted because of the short spin-spin relaxation times, typically under 1 microsecond, of most biologically relevant paramagnetic species. Recent advances i... | ['Animals', 'Artifacts', 'Blood Vessels', 'Electron Spin Resonance Spectroscopy', 'Female', 'Image Processing, Computer-Assisted', 'Magnetics', 'Mice', 'Mice, Inbred C3H', 'Phantoms, Imaging', 'Spin Labels', 'Tail'] | 9,339,442 | [['B01.050'], ['E05.047'], ['A07.015'], ['E05.196.867.519.274'], ['L01.224.308'], ['H01.671.493'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.388', 'B01.050.150.900.649.313.992.635.505.500.400.388'], ['E07.671'], ['D02.389.678'], ['A13.895']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of exercise on left ventricular-arterial coupling assessed in the pressure-volume plane. | The left ventricle (LV) and arterial system are nearly optimally coupled to produce stroke work (SW) at rest. However, the effect of exercise on the coupling between the LV and arterial system has not been directly determined. We evaluated 11 dogs who were instrumented to determine LV volume from three diameters. The L... | ['Adrenergic beta-Antagonists', 'Animals', 'Arteries', 'Blood Pressure', 'Blood Volume', 'Coronary Vessels', 'Dogs', 'Hemodynamics', 'Metoprolol', 'Physical Exertion', 'Ventricular Function, Left'] | 8,098,914 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['B01.050'], ['A07.015.114'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.188.130', 'G09.330.380.092'], ['A07.015.114.269', 'A07.015.908.194'], ['B01.050.150.900.649.313.750.250.216.200'], ['G09.330.380'], ['D02.033.100.624.698.573', 'D02.033.755.62... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of 'dilute-and-shoot' liquid chromatography-high resolution mass spectrometry in preclinical research: application to a DMPK study of perhexiline in mouse plasma. | This work describes a simple, sensitive and rapid liquid chromatography-high resolution mass spectrometry method for the quantitation of perhexiline and the simultaneous detection of perhexiline metabolites in C57bl/6 mice plasma. Only 5 ìL of plasma was used for analysis. Pretreatment was limited to a 100-fold dilutio... | ['Animals', 'Chromatography, Liquid', 'Drug Evaluation, Preclinical', 'Female', 'Mice', 'Mice, Inbred C57BL', 'Perhexiline', 'Tandem Mass Spectrometry'] | 26,517,851 | [['B01.050'], ['E05.196.181.400'], ['E05.290.750', 'E05.337.550'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D03.383.621.644'], ['E05.196.566.880']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stability of direct and transfer effects of number-conservation training with mentally retarded adults. | Twenty nonconserving retarded adults were assigned to equated training and control groups (n = 10 in each group). Training-group subjects were given multiple-strategy training for number conservation consisting of: demonstrating effects of addition-subtraction; negation of addition-subtraction by inverse operations; an... | ['Adult', 'Concept Formation', 'Humans', 'Intellectual Disability', 'Mathematics', 'Middle Aged', 'Size Perception', 'Transfer, Psychology'] | 677,180 | [['M01.060.116'], ['F02.463.785.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['H01.548'], ['M01.060.116.630'], ['F02.463.593.725', 'F02.463.593.778.794'], ['F02.463.425.910']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of supplemental oxygen on maternal and neonatal oxygenation in elective cesarean section under spinal anesthesia: a randomized controlled trial. | The use of supplemental oxygen in uncomplicated cesarean deliveries under spinal anesthesia has been thoroughly investigated during recent decades. The aim of this study was to determine the benefits for both mother and infant of administering supplemental, low-dose oxygen via a nasal cannula versus having no supplemen... | ['Adult', 'Anesthesia, Obstetrical', 'Anesthesia, Spinal', 'Cesarean Section', 'Elective Surgical Procedures', 'Female', 'Humans', 'Infant, Newborn', 'Oxygen', 'Parturition', 'Perioperative Care', 'Pregnancy'] | 24,696,860 | [['M01.060.116'], ['E03.155.364'], ['E03.155.086.331'], ['E04.520.252.500'], ['E04.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['D01.268.185.550', 'D01.362.670'], ['G08.686.784.769.490'], ['E02.760.731', 'E04.604', 'N02.421.585.722'], ['G08.686.784.769']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Perceptual quality metric with internal generative mechanism. | Objective image quality assessment (IQA) aims to evaluate image quality consistently with human perception. Most of the existing perceptual IQA metrics cannot accurately represent the degradations from different types of distortion, e.g., existing structural similarity metrics perform well on content-dependent distorti... | ['Algorithms', 'Animals', 'Artificial Intelligence', 'Bayes Theorem', 'Databases, Factual', 'Humans', 'Image Processing, Computer-Assisted', 'Models, Theoretical', 'Signal-To-Noise Ratio', 'Video Recording', 'Visual Perception'] | 22,910,116 | [['G17.035', 'L01.224.050'], ['B01.050'], ['G17.035.250', 'L01.224.050.375'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E05.599'], ['E05.318.370.800.875', 'E05.318... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Diagnosis of retinal vascular changes in diabetic children by means of fluorescein-angiography (author's transl)]. | By means of fluorescein-angiography diabetic microangiopathy can be earlier revealed than by means of ophthalmoscopy. 36 children with diabetes (aged 6,25-15,5 years, x 11,6 years) with a duration of the diabetes between 0 and 12,75 years (x 3,9) were submitted to fluorescein - angiography, in 20 cases a follow up stud... | ['Adolescent', 'Child', 'Diabetes Mellitus, Type 1', 'Diabetic Retinopathy', 'Fluorescein Angiography', 'Humans', 'Time Factors'] | 7,432,359 | [['M01.060.057'], ['M01.060.406'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['E01.370.370.050.350', 'E01.370.380.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.910.857']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The relationship between sperm morphology and in vitro fertilization ability in mice. | In vitro fertilization (IVF) is widely used in reproduction research, but the sperm of some inbred strains of mice yield low fertilization rates in IVF. To determine the cause of this problem, we examined the effect of epididymal sperm morphology, in particular, tail bending and the presence and type of cytoplasmic dro... | ['Animals', 'Cytoplasm', 'Epididymis', 'Female', 'Fertilization in Vitro', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C3H', 'Mice, Inbred C57BL', 'Mice, Inbred DBA', 'Semen Preservation', 'Species Specificity', 'Spermatozoa'] | 16,757,880 | [['B01.050'], ['A11.284.430.214'], ['A05.360.444.371'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['B01.050.050.199.520.520.388', 'B01.050.150.900.649.313.992.635.505.500.400.388'], ['B01.050.0... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genistein is an effective stimulator of sex hormone-binding globulin production in hepatocarcinoma human liver cancer cells and suppresses proliferation of these cells in culture. | Studies have indicated a correlation between a high level of urinary lignans and isoflavonoid phytoestrogens, particularly genistein, and a low incidence of hormone-dependent cancers, such as breast and prostate cancer. Previously it has been observed that a vegetarian diet is associated with high plasma levels of sex ... | ['Carcinoma, Hepatocellular', 'Cell Division', 'Genistein', 'Humans', 'Isoflavones', 'Liver Neoplasms', 'Sex Hormone-Binding Globulin', 'Tumor Cells, Cultured'] | 8,212,077 | [['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D03.383.663.283.266.450.400.375', 'D03.633.100.150.266.450.400.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.663.283.266.450.400', 'D... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A multidisciplinary fall prevention program for elderly persons: a feasibility study. | Falling is a common problem among elderly people and has many negative consequences. In the Netherlands, there is a need for effective fall prevention interventions aimed at elderly persons with an increased risk of falling. For this reason, we adapted a successful British fall prevention program comprising a medical o... | ['Accidental Falls', 'Activities of Daily Living', 'Aged', 'Family Practice', 'Feasibility Studies', 'Female', 'Geriatric Assessment', 'Geriatric Nursing', 'Health Planning Guidelines', 'Humans', 'Male', 'Needs Assessment', 'Netherlands', 'Nursing Assessment', 'Nursing Evaluation Research', 'Occupational Therapy', 'Out... | 18,555,160 | [['N06.850.135.122'], ['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['H02.403.340.500'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.42... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Possibility of age regulation of the natriuretic peptide C-receptor in human platelets. | Natriuretic peptide binding sites on platelets have been hypothesized to act as clearance receptors; however, there is no clear definition of the function of this receptor. The aim of the study was: 1) to characterize natriuretic peptide receptors in human platelets by original competition study; 2) to evaluate a possi... | ['Adult', 'Aged', 'Aging', 'Atrial Natriuretic Factor', 'Binding, Competitive', 'Blood Platelets', 'Female', 'Guanylate Cyclase', 'Humans', 'Iodine Radioisotopes', 'Male', 'Metabolic Clearance Rate', 'Middle Aged', 'Natriuretic Peptide, Brain', 'Natriuretic Peptide, C-Type', 'Receptors, Atrial Natriuretic Factor', 'Ref... | 11,227,736 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['A11.118.188', 'A15.145.229.188'], ['D08.811.520.650.600', 'D12.644.360.350', 'D12.776.476.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.380... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Technical evaluation as a competence of the nurse: reflections and pressupositions in the scenario of science and technology]. | This article approaches the concepts and presuppositions related to technical evaluation, through the use of equipment, inspired by the national system of science and technology. It shows the necessarily of the professional nurse to develop competencies such that, beginning with their formation, they are stimulated to ... | ['Biomedical Technology', 'Clinical Competence', 'Nursing'] | 17,340,738 | [['J01.897.120.050'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['H02.478', 'N04.452.758.377']] | ['Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 |
Considering Plasma Insulin Concentrations in Adaptive Model Predictive Control for Artificial Pancreas Systems. | Adaptive and personalized model predictive control (MPC) algorithms that explicitly consider insulin dosing constraints are necessary to prevent overdose-induced hypoglycemia in type 1 diabetes. A personalized plasma insulin concentration (PIC) estimator is integrated with adaptive models to characterize the temporal d... | ['Algorithms', 'Blood Glucose', 'Blood Glucose Self-Monitoring', 'Diabetes Mellitus, Type 1', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Insulin Infusion Systems', 'Pancreas, Artificial', 'Predictive Value of Tests'] | 30,441,339 | [['G17.035', 'L01.224.050'], ['D09.947.875.359.448.500'], ['E01.370.225.124.100.105', 'E01.370.374.100', 'E01.370.520.100', 'E02.900.950.500', 'E05.200.124.100.105'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['D06.472.699.587.200.500.62... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Characteristics of spasm-induced vessels in patients with vasospastic angina and a history of syncope]. | One hundred and eighty-seven consecutive patients with vasospastic angina and coronary spasm provoked by intracoronary injection of acetylcholine and/or ergonovine were treated from January 1991 to June 1997. Fifteen of these patients, 14 men and one woman (mean age of 63 years old), had a history of syncope. There wer... | ['Acetylcholine', 'Angina Pectoris', 'Coronary Vasospasm', 'Coronary Vessels', 'Ergonovine', 'Female', 'Humans', 'Male', 'Middle Aged', 'Syncope'] | 9,666,386 | [['D02.092.211.111'], ['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['C14.280.647.250.295', 'C14.907.585.250.295'], ['A07.015.114.269', 'A07.015.908.194'], ['D03.132.327.287.262', 'D03.633.400.439.262'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.597.606.358.800.600... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Induction of mammary neoplasms in the Sprague-Dawley rat by 430keV neutrons and X-rays. | Female noninbred Sprague-Dawley rats were exposed to single doses of 0.28, 0.56, and 0.85 gray (Gy = 1 J/kg or 100 rads) of X-rays or 0.001, 0.004, 0.016, and 0.064 Gy of 430-keV neutrons at 62 +/- 1 days of age and were then observed over the rest of their lives for the appearance of mammary neoplasia. As mammary neop... | ['Adenocarcinoma', 'Adenofibroma', 'Age Factors', 'Animals', 'Dose-Response Relationship, Radiation', 'Female', 'Longevity', 'Mammary Neoplasms, Experimental', 'Neoplasms, Radiation-Induced', 'Neutrons', 'Particle Accelerators', 'Rats', 'Time Factors', 'X-Rays'] | 6,928,995 | [['C04.557.470.200.025'], ['C04.557.450.565.590.595.050', 'C04.557.470.625.050'], ['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['G07.345.124.519', 'G07.540'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.4... | ['Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
New insights into the functional significance of the acidic region of the unique N-terminal extension of cardiac troponin I. | Previous structural studies indicated a special functional role for an acidic region composed of residues 1-10 in the unique N-terminal peptide of cardiac troponin I (cTnI). Employing LC-MS/MS, we determined the presence of phosphorylation sites at S5/S6 in cTnI from wild type mouse hearts as well as in hearts of mice ... | ['Adenosine Triphosphatases', 'Animals', 'Calcium', 'Cardiomyopathy, Dilated', 'Gene Expression', 'Humans', 'Isometric Contraction', 'Kinetics', 'Male', 'Mice', 'Mice, Transgenic', 'Muscle Tonus', 'Mutation', 'Myocardium', 'Myofibrils', 'Phosphorylation', 'Protein Isoforms', 'Protein Kinase C-epsilon', 'Protein Structu... | 22,940,544 | [['D08.811.277.040.025'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['C14.280.195.160', 'C14.280.238.070', 'C16.320.488.750'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494.472'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Psychiatric resident education in intellectual disabilities: one program's ten years of experience. | OBJECTIVE: The authors evaluated the confidence and willingness of resident graduates to treat individuals with intellectual disability (ID), following a residency rotation in developmental disability.METHODS: Thirty-two graduates of a single residency program were surveyed regarding their post-residency experience wit... | ['Attitude of Health Personnel', 'Career Choice', 'Clinical Competence', 'Curriculum', 'Data Collection', 'Humans', 'Intellectual Disability', 'Internship and Residency', 'Ohio', 'Psychiatry', 'Specialization'] | 18,079,502 | [['F01.100.050', 'N05.300.100'], ['F02.463.785.373.346.400'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.158'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], [... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
Malignant lymphomas in Papua New Guinea: an immunohistological study of 125 cases. | A total of 179 cases of lymphoma, both nodal and extranodal, recorded in the Papua New Guinea Tumor Registry were reviewed and classified by the updated Kiel classification. Fifteen (8.4%) were Hodgkin's disease, 39 (21.8%) probable Burkitt's lymphoma (poorly preserved), 46 (25.7%) Burkitt's lymphoma, 33 (18.4%) Burkit... | ['Humans', 'Immunohistochemistry', 'Lymphoma', 'Lymphoma, B-Cell', 'Lymphoma, T-Cell', 'Papua New Guinea'] | 8,714,268 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['C04.557.386', 'C15.604.515.569',... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
[Treatment of genital condylomatous diseases with electric fulguration and interferon]. | The therapeutical effectiveness of beta-interferon and the possibility of reducing the incidence of relapses were evaluated by submitting two groups of 10 patients each to various treatment. The first group has been treated only by electro-fulguration and the second also by parenteral administration of beta-interferon.... | ['Adult', 'Combined Modality Therapy', 'Condylomata Acuminata', 'Electrocoagulation', 'Female', 'Genital Neoplasms, Female', 'Genital Neoplasms, Male', 'Humans', 'Interferon-beta', 'Male', 'Neoplasm Recurrence, Local'] | 1,812,573 | [['M01.060.116'], ['E02.186'], ['C01.221.812.640.220', 'C01.778.640.220', 'C01.925.256.650.810.217', 'C01.925.813.220', 'C01.925.825.810.110', 'C01.925.928.914.217', 'C17.800.838.790.810.110'], ['E02.154.402', 'E04.014.170.402'], ['C04.588.945.418', 'C13.351.937.418'], ['C04.588.945.440', 'C12.294.260', 'C12.758.409'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ultrasonographic detection of abnormal fetal growth with the gestational age-independent, transverse cerebellar diameter/abdominal circumference ratio. | OBJECTIVES: We prospectively evaluated the accuracy of a gestational age-independent method of detecting abnormal growth, the transverse cerebellar diameter/abdominal circumference ratio, and compared this with standard ultrasonographic methods of growth assessment.STUDY DESIGN: We prospectively studied 825 low-risk ob... | ['Abdomen', 'Analysis of Variance', 'Biometry', 'Cerebellum', 'Embryonic and Fetal Development', 'Female', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Infant, Small for Gestational Age', 'Logistic Models', 'Multivariate Analysis', 'Odds Ratio', 'Predictive Value of Tests', 'Pregnancy', 'Prospective Studies', 'Refe... | 7,943,070 | [['A01.923.047'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.740.225', 'N06.850.505.200'], ['A08.186.211.132.810.428.200'], ['G07.345.500.325', 'G08.686.784.170'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.06... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mitochondrial abnormalities in Menkes' kinky hair disease (MKHD). Electron-microscopic study of the brain from an autopsy case. | The brain of an autopsy case of Menkes' kinky hair disease (MKHD), after routine histological examination, was studied extensively by electron microscopy, particularly the mitochondrial alteration. There were widespread mitochondrial abnormalities, including enlargement with tubulo-vesiculated cristae, swelling, and de... | ['Brain', 'Brain Diseases, Metabolic', 'Caudate Nucleus', 'Cerebral Cortex', 'Globus Pallidus', 'Humans', 'Infant', 'Male', 'Menkes Kinky Hair Syndrome', 'Microscopy, Electron', 'Mitochondria', 'Mitochondrial Swelling', 'Purkinje Cells', 'Thalamic Nuclei'] | 6,868,958 | [['A08.186.211'], ['C10.228.140.163', 'C18.452.132'], ['A08.186.211.200.885.287.249.487.550.184'], ['A08.186.211.200.885.287.500'], ['A08.186.211.200.885.287.249.487.397'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C10.228.140.163.100.540', 'C10.597.606.360.455.687', 'C16.320.322.500.687', 'C1... | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Akt Kinase-Interacting Protein 1 Signals through CREB to Drive Diffuse Malignant Mesothelioma. | Diffuse malignant mesothelioma (DMM) is a tumor of serosal membranes with propensity for progressive local disease. Because current treatment options are largely ineffective, novel therapeutic strategies based on molecular mechanisms and the disease characteristics are needed to improve the outcomes of patients with th... | ['Animals', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Survival', 'Cyclic AMP Response Element-Binding Protein', 'Cyclic AMP-Dependent Protein Kinases', 'DNA-Binding Proteins', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lung Neoplasms', 'Mesothelioma', 'Mesothelioma, Malignant', 'Mice', 'Mice, SCID', 'Neoplasm P... | 26,294,214 | [['B01.050'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['D12.776.260.108.184', 'D12.776.930.127.184'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['D12.776.260'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520'... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition of Ser/Thr phosphatase PPM1D induces neutrophil differentiation in HL-60 cells. | Protein phosphatase Magnesium-dependent 1, Delta (PPM1D) is a wild-type p53-inducible Ser/Thr phosphatase that acts as a negative regulator of the p53 tumor suppressor. Gene amplification and overexpression of PPM1D have been reported in various cancers including leukemia and neuroblastoma. Therefore, PPM1D is a promis... | ['Cell Differentiation', 'Cell Proliferation', 'Dose-Response Relationship, Drug', 'Enzyme Inhibitors', 'HL-60 Cells', 'Humans', 'Neutrophils', 'Protein Phosphatase 2C', 'Structure-Activity Relationship', 'Tretinoin'] | 28,486,685 | [['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.519.389'], ['A11.251.210.190.465', 'A11.251.860.180.465', 'A11.627.340.360.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', ... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficient transcriptional antitermination from the Escherichia coli cytoplasmic membrane. | The BglG protein is a transcriptional antiterminator acting within the beta-glucoside operon of Escherichia coli by binding to a specific sequence motif in the growing mRNA. Binding of BglG prevents formation of the terminator stem-loop structure, thereby causing the RNA polymerase to continue transcription. Activity o... | ['Bacterial Proteins', 'Bacteriophage M13', 'Capsid', 'Capsid Proteins', 'Cell Fractionation', 'Cell Membrane', 'Cytoplasm', 'Escherichia coli', 'Gene Expression Regulation, Bacterial', 'Membrane Proteins', 'Phosphoenolpyruvate Sugar Phosphotransferase System', 'Phosphorylation', 'Protein Transport', 'RNA-Binding Prote... | 11,327,758 | [['D12.776.097'], ['B04.123.205.250', 'B04.123.370.400.250', 'B04.280.400.400.250'], ['A21.249.500.250'], ['D12.776.964.970.600.550'], ['E05.242.251'], ['A11.284.149'], ['A11.284.430.214'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.308.300'], ['D12.776.543'], ['D05.500.562.484', 'D08.811.600.700', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Isozyme-specific interaction of protein kinase Cä with mitochondria dissected using live cell fluorescence imaging. | PKCä signaling to mitochondria has been implicated in both mitochondrial apoptosis and metabolism. However, the mechanism by which PKCä interacts with mitochondria is not well understood. Using FRET-based imaging, we show that PKCä interacts with mitochondria by a novel and isozyme-specific mechanism distinct from its ... | ['Amino Acid Sequence', 'Animals', 'Binding Sites', 'COS Cells', 'Cell Line', 'Chlorocebus aethiops', 'Fluorescence Resonance Energy Transfer', 'Humans', 'Immunoblotting', 'Indoles', 'Isoenzymes', 'Luminescent Proteins', 'Maleimides', 'Microscopy, Fluorescence', 'Mitochondria', 'Molecular Imaging', 'Molecular Sequence ... | 22,988,234 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['A11.251.210.172.500', 'A11.329.228.220'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['E05.196.712.516.600.676.500', 'G01.154.240.280', 'G02.111.255.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Study of arterial aneurysms. | A review of 46 patients operated for arterial aneurysms over an eight years period is presented. Twenty-nine patients developed aneurysm following vascular trauma while 17 had atherosclerotic aneurysms. Thirty-one patients presented with painless swelling or swelling with mild pain and four patients with frank rupture.... | ['Adolescent', 'Adult', 'Aneurysm', 'Arteries', 'Arteriosclerosis', 'Diagnosis, Differential', 'Female', 'Humans', 'Male', 'Middle Aged'] | 1,479,637 | [['M01.060.057'], ['M01.060.116'], ['C14.907.055'], ['A07.015.114'], ['C14.907.137.126'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Corneal endothelial safety following subconjunctival and intrastromal injection of bevacizumab for corneal neovascularization. | The purpose of this study is to determine the effect on endothelial cell density and morphology of combined subconjunctival and intracorneal injection of bevacizumab for the treatment of corneal neovascularization (NV). The charts and specular microscopy images of ten consecutive patients with corneal NV, who received ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Angiogenesis Inhibitors', 'Antibodies, Monoclonal, Humanized', 'Bevacizumab', 'Corneal Neovascularization', 'Endothelial Cells', 'Endothelium, Corneal', 'Female', 'Humans', 'Injections, Intraocular', 'Male', 'Middle Aged', 'Young Adult'] | 23,722,674 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
HIV resistance: frequency, testing, mechanisms. | Recent data suggest that the prevalence of drug-resistant HIV in newly diagnosed patients may have leveled off at approximately 10% over the past several years. Further, there is some indication that the rates of emergence of resistance during long-term treatment have decreased in recent years with optimization of anti... | ['Drug Resistance, Viral', 'HIV', 'HIV Infections', 'Humans', 'Microbial Sensitivity Tests'] | 18,073,450 | [['G06.225.420', 'G06.920.225', 'G07.690.773.984.269.420'], ['B04.820.650.589.650.350'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.40... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Analysis for predicting the prognostic factors of gastrointestinal tract leiomyosarcoma using MIB-1 and DNA flow cytometry]. | PURPOSE: The present study was undertaken to investigate the possibility of determining a prognosis for gastrointestinal tract leiomyosarcoma with the use of DNA analysis and MIB-1 staining.SUBJECTS AND METHODS: Malignant tumors originating in smooth muscle of the gastrointestinal tract, surgically excised from 23 lesi... | ['Adult', 'Aged', 'Aneuploidy', 'Antigens, Nuclear', 'DNA, Neoplasm', 'Female', 'Flow Cytometry', 'Gastrointestinal Neoplasms', 'Humans', 'Ki-67 Antigen', 'Leiomyosarcoma', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Nuclear Proteins', 'Ploidies', 'Prognosis', 'Staining and Labeling'] | 9,589,056 | [['M01.060.116'], ['M01.060.116.100'], ['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['D12.776.660.625', 'D23.050.290'], ['D13.444.308.425'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.3... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fragment detection of Coleopteran and Triatomine insects in experimentally contaminated acai pulp and sugarcane juice. | INTRODUCTION: Oral transmission of acute Chagas disease is an emerging public health concern. This study aimed to detect insect fragments in experimentally contaminated food, by comparing triatomines with other insects.METHODS: Food samples were experimentally contaminated with insects, processed to recover their fragm... | ['Animals', 'Chagas Disease', 'Coleoptera', 'Food Parasitology', 'Fruit and Vegetable Juices', 'Humans', 'Insect Vectors', 'Polymerase Chain Reaction', 'Saccharum', 'Triatominae'] | 31,859,942 | [['B01.050'], ['C01.610.752.300.900.200', 'C01.920.625'], ['B01.050.500.131.617.720.500.500.375'], ['H01.158.273.688.500', 'J01.576.423.850.730.500.249.650', 'N06.850.460.400.650', 'N06.850.601.500.249.650'], ['G07.203.100.606', 'J02.200.606'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.335.188.100.500'... | ['Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Effects of cadmium on preimplantation and early postimplantation mouse embryos in vitro with special reference to their trophoblastic invasiveness. | Cadmium chloride, at concentrations of 0.5 or 1 microgram/ml medium, did not affect the trophoblastic invasiveness of mouse embryos treated for 24 hours at 4-cell and morula stages. At higher concentrations of 5 or 10 micrograms/ml medium, most treated embryos in vitro underwent degeneration while a few survivors forme... | ['Animals', 'Blastocyst', 'Cadmium', 'Cell Differentiation', 'Embryonic Development', 'Female', 'In Vitro Techniques', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Pregnancy', 'Trophoblasts'] | 3,575,246 | [['B01.050'], ['A16.254.500'], ['D01.268.556.137', 'D01.268.956.061', 'D01.552.544.137'], ['G04.152'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['E05.481'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['B01.050.050.199.520.520.4... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Overexpression of the human angiotensin II type 1 receptor in the rat heart augments load induced cardiac hypertrophy. | Angiotensin II is known to stimulate cardiac hypertrophy and contractility. Most angiotensin II effects are mediated via membrane bound AT1 receptors. However, the role of myocardial AT1 receptors in cardiac hypertrophy and contractility is still rarely defined. To address the hypothesis that increased myocardial AT1 r... | ['Angiotensin II', 'Animals', 'Animals, Genetically Modified', 'Animals, Newborn', 'Binding, Competitive', 'Blood Pressure', 'Calcium', 'Cardiomegaly', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Gene Expression Regulation', 'Heart Ventricles', 'Hemodynamics', 'Humans', 'Membranes', 'Myocardium', 'Or... | 11,692,158 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['B01.050.050.282'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D01.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Motor disability in children in three birth cohorts. | A systematic registration was carried out in 1985-1986 and 1989 in 14 French 'departments' in order to assess whether the prevalence rates of different components of motor disability (MD) in three different birth cohorts (1972, 1976 and 1981) had changed at a time when the preterm birth rate and neonatal mortality were... | ['Adolescent', 'Cerebral Palsy', 'Child', 'Cohort Studies', 'Disabled Persons', 'Female', 'France', 'Humans', 'Male', 'Movement Disorders', 'Prevalence', 'Risk Factors'] | 1,428,493 | [['M01.060.057'], ['C10.228.140.140.254'], ['M01.060.406'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['M01.150'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.662'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Evidence that binding site occupancy is necessary and sufficient for effective major histocompatibility complex (MHC) class II transport through the secretory pathway redefines the primary function of class II-associated invariant chain peptides (CLIP). | Invariant chain (Ii) associates with newly synthesized class II molecules in the endoplasmic reticulum (ER), an interaction that has been shown to interfere with peptide binding to class II molecules. The class II-associated invariant chain peptide (CLIP) region (residues 81-104) of Ii is believed to mediate this inhib... | ['Amino Acid Sequence', 'Animals', 'Antigens, Differentiation, B-Lymphocyte', 'Base Sequence', 'Biological Transport', 'COS Cells', 'Endoplasmic Reticulum', 'Genetic Variation', 'Golgi Apparatus', 'Histocompatibility Antigens Class II', 'Major Histocompatibility Complex', 'Mice', 'Molecular Sequence Data', 'Peptides', ... | 8,920,896 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D23.050.301.264.051', 'D23.101.100.150'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G03.143'], ['A11.251.210.172.500', 'A11.329.228.220'], ['A11.284.430.214.190.875.248'], ['G05.365'], ['A11.284.430.214.190.875.336'], ['D12.776.395.550.509',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Liquid chromatography tandem mass spectrometry determination of selected synthetic cathinones and two piperazines in oral fluid. Cross reactivity study with an on-site immunoassay device. | Since the past few years, several synthetic cathinones and piperazines have been introduced into the drug market to substitute illegal stimulant drugs such as amphetamine and derivatives or cocaine due to their unregulated situation. These emerging drugs are not usually included in routine toxicological analysis. We de... | ['Alkaloids', 'Calibration', 'Chromatography, High Pressure Liquid', 'Cross Reactions', 'Humans', 'Immunoassay', 'Piperazines', 'Tandem Mass Spectrometry'] | 25,482,853 | [['D03.132'], ['E05.978.155'], ['E05.196.181.400.300'], ['G12.122.281'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['D03.383.606'], ['E05.196.566.880']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Does quantitative ultrasound imaging enhance precision and discrimination? | The aim of this study was to compare quantitative ultrasound (QUS) measurements obtained using a new calcaneal QUS imaging device with a conventional non-imaging device using fixed transducers. The study group consisted of 340 healthy women with no risk factors associated with osteoporosis (176 premenopausal and 164 po... | ['Absorptiometry, Photon', 'Adult', 'Aged', 'Aging', 'Bone Density', 'Calcaneus', 'Female', 'Humans', 'Linear Models', 'Middle Aged', 'Multivariate Analysis', 'Osteoporosis, Postmenopausal', 'Postmenopause', 'Premenopause', 'Quality Control', 'Spinal Fractures', 'Time Factors', 'Ultrasonography'] | 10,912,845 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['G11.427.100'], ['A02.835.232.043.300.710.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Successful percutaneous drainage of duodenal hematoma after blunt trauma. | Duodenal hematoma after blunt trauma is usually treated nonoperatively with bowel rest, nasogastric tube suction, and intravenous hydration. We report a case in which obstructive symptoms persisted despite more than 2 weeks of conservative management. An ultrasound-guided percutaneous drain was placed, with successful ... | ['Adolescent', 'Catheterization', 'Drainage', 'Duodenal Diseases', 'Hematoma', 'Humans', 'Male', 'Wounds, Nonpenetrating'] | 18,778,981 | [['M01.060.057'], ['E02.148', 'E05.157'], ['E02.309', 'E04.237'], ['C06.405.469.275'], ['C23.550.414.838'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.974']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Yield of peripheral sodium channels gene screening in pure small fibre neuropathy. | BACKGROUND: Neuropathic pain is common in peripheral neuropathy. Recent genetic studies have linked pathogenic voltage-gated sodium channel (VGSC) variants to human pain disorders. Our aims are to determine the frequency of SCN9A, SCN10A and SCN11A variants in patients with pure small fibre neuropathy (SFN), analyse th... | ['Aged', 'Female', 'Genetic Testing', 'Genetic Variation', 'Humans', 'Male', 'Middle Aged', 'NAV1.7 Voltage-Gated Sodium Channel', 'NAV1.8 Voltage-Gated Sodium Channel', 'NAV1.9 Voltage-Gated Sodium Channel', 'Predictive Value of Tests', 'Retrospective Studies', 'Small Fiber Neuropathy'] | 30,554,136 | [['M01.060.116.100'], ['E01.370.225.562', 'E05.200.562', 'E05.393.435', 'N02.421.308.430', 'N02.421.726.233.221'], ['G05.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D12.776.157.530.400.875.750.700', 'D12.776.543.550.450.875.750.700', 'D12.776.543.585.400.875.750.700', 'D12.776.631.960... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ultrarapid electrophoretic transfer of high and low molecular weight proteins using heat. | An ultrarapid method for the electrophoretic transfer of high and low molecular weight proteins to nitrocellulose membranes following sodium dodecyl sulfate (SDS) polyacrylamide gel is described here. The transfer was performed with heated (70-75 degrees C) normal transfer buffer from which methanol had been omitted. C... | ['Blotting, Western', 'Buffers', 'Collodion', 'Electrophoresis, Polyacrylamide Gel', 'HeLa Cells', 'Hot Temperature', 'Humans', 'Molecular Weight', 'Proteins'] | 19,378,057 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D27.720.470.280'], ['D25.720.099.500.439', 'J01.637.051.720.099.500.439'], ['E05.196.401.402', 'E05.301.300.319'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['G01.906.595.543', 'G16.500.275.063.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
School violence and the culture of honor. | We investigated the hypothesis that a sociocultural variable known as the culture of honor would be uniquely predictive of school-violence indicators. Controlling for demographic characteristics associated in previous studies with violent crime among adults, we found that high-school students in culture-of-honor states... | ['Adolescent', 'Aggression', 'Culture', 'Female', 'Firearms', 'Hierarchy, Social', 'Homicide', 'Humans', 'Male', 'Moral Development', 'Rejection, Psychology', 'Risk Assessment', 'Risk Factors', 'Schools', 'Self Concept', 'Social Identification', 'Social Values', 'Socioeconomic Factors', 'Truth Disclosure', 'United Stat... | 19,843,260 | [['M01.060.057'], ['F01.145.126.125', 'F01.145.813.045'], ['I01.076.201.450', 'I01.880.853.100'], ['J01.637.870.350'], ['I01.880.853.200'], ['I01.198.240.470', 'I01.880.735.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.747.616', 'F01.829.500.679', 'K01.752.566.739'], ['F01.145.813.565'], ['E05.318.7... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Bypass grafting to the popliteal artery in limbs with occluded crural arteries. | Intraoperative completion angiograms of 47 femoropopliteal bypasses in limbs with occluded crural arteries were reviewed to identify the angiographic determinants of early outcome. Of 28 limbs in which the foot vessels were available for analysis, only 2 (7%) had an intact pedal circulation, and 18 limbs demonstrated n... | ['Adult', 'Aged', 'Aged, 80 and over', 'Arterial Occlusive Diseases', 'Blood Vessel Prosthesis', 'Female', 'Femoral Artery', 'Follow-Up Studies', 'Foot', 'Humans', 'Leg', 'Male', 'Middle Aged', 'Polytetrafluoroethylene', 'Popliteal Artery', 'Radiography', 'Saphenous Vein', 'Time Factors', 'Umbilical Veins'] | 2,063,964 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.137'], ['E07.695.110'], ['A07.015.114.351'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A01.378.610.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['M01.060.116.630']... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Three dimensional anatomical exploration of the anterior hard palate at the level of the third ruga for the placement of mini-implants--a cone-beam CT study. | AIM: The aim of this retrospective investigation was to measure vertical bone thickness on the hard palate, determine areas with adequate bone for the insertion of orthodontic mini-implants (MIs), and provide clinical guidelines for identification of those areas.MATERIALS AND METHODS: Pre-treatment records of 1007 pati... | ['Anatomic Landmarks', 'Cephalometry', 'Cone-Beam Computed Tomography', 'Dental Implants', 'Dental Models', 'Humans', 'Imaging, Three-Dimensional', 'Miniaturization', 'Mouth Mucosa', 'Orthodontic Anchorage Procedures', 'Palate, Hard', 'Retrospective Studies'] | 25,564,503 | [['A01.111'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['E01.370.350.700.810.810.490', 'E01.370.350.825.810.810.399'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['E06.261', 'J01.897.280.500.545.129.200', 'L01.178.820.090.545.129.200'], ['B01.050.150.900.649.313.... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Transcriptomic response of durum wheat to cold stress at reproductive stage. | Understanding the genetic basis of cold tolerance is a key step towards obtaining new and improved crop varieties. Current geographical distribution of durum wheat in Argentina exposes the plants to frost damage when spikes have already emerged. Biochemical pathways involved in cold tolerance are known to be early acti... | ['Argentina', 'Cold Temperature', 'Cold-Shock Response', 'Freezing', 'Gene Expression Regulation, Plant', 'Genes, Plant', 'Genotype', 'MicroRNAs', 'RNA, Long Noncoding', 'Transcription Factors', 'Transcriptome', 'Triticum'] | 30,798,485 | [['Z01.107.757.077'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G07.775.249'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['G05.308.375'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.380'], ['D13.1... | ['Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Histocompatibility antigens and geographic tongue. | The HLA-A, B and HLA-DR antigens were investigated in 50 unrelated Greek persons with geographic tongue and in 380 healthy control persons. An increased incidence of DR5 and DRW6 antigens was observed in the blood of persons with geographic tongue. Ten (20%) of them had the DRW6 antigen, and it was significantly increa... | ['Adolescent', 'Adult', 'Aged', 'Case-Control Studies', 'Chi-Square Distribution', 'Glossitis, Benign Migratory', 'Greece', 'HLA Antigens', 'HLA-B Antigens', 'HLA-B51 Antigen', 'HLA-DR2 Antigen', 'HLA-DR5 Antigen', 'HLA-DR6 Antigen', 'Humans', 'Middle Aged', 'Risk'] | 8,233,428 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C07.465.910.363.447'], ['Z01.542.383'], ['D23.050.301.500.450', 'D23.050.705.552.450'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Birthweight and gestational age by ethnic group, England and Wales 2005: introducing new data on births. | Low birthweight babies and babies born preterm are at increased risk of morbidity and mortality in the first year of life, as well as in the longer-term. Since information on ethnic group is not recorded at birth registration in England and Wales, it has not been possible to produce routine statistics on birthweight or... | ['Adolescent', 'Adult', 'Birth Weight', 'England', 'Ethnic Groups', 'Female', 'Gestational Age', 'Humans', 'Infant, Low Birth Weight', 'Infant, Newborn', 'Marital Status', 'Maternal Age', 'Middle Aged', 'Pregnancy', 'Pregnancy Outcome', 'Socioeconomic Factors', 'Wales', 'Young Adult'] | 18,810,886 | [['M01.060.057'], ['M01.060.116'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['Z01.542.363.300'], ['M01.686.754', 'N01.224.317'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Single- and double-cubane clusters in the multiple oxidation states [VFe(3)S(4)](3+,2+,1+). | A new series of cubane-type [VFe(3)S(4)](z)() clusters (z = 1+, 2+, 3+) has been prepared as possible precursor species for clusters related to those present in vanadium-containing nitrogenase. Treatment of [(HBpz(3))VFe(3)S(4)Cl(3)](2)(-) (2, z = 2+), protected from further reaction at the vanadium site by the tris(py... | ['Catalysis', 'Crystallography, X-Ray', 'Iron', 'Ligands', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Molecular Conformation', 'Molecular Structure', 'Molybdenum', 'Nitrogenase', 'Organometallic Compounds', 'Oxidation-Reduction', 'Spectroscopy, Mossbauer', 'Sulfur', 'Temperature', 'Vanadium'] | 11,896,732 | [['G02.130'], ['E05.196.309.742.225'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D27.720.470.480'], ['E05.196.867.519'], ['E05.599.595'], ['G02.111.570.820'], ['G02.111.570', 'G02.466'], ['D01.268.556.555', 'D01.268.956.500', 'D01.552.544.555'], ['D08.811.682.647'], ['D02.691'], ['G02.700', 'G03.295.... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of the toxicity of smoke from conventional and harm reduction cigarettes using human embryonic stem cells. | This study evaluated the hypothesis that smoke from harm reduction cigarettes impedes attachment and proliferation of H9 human embryonic stem cells (hESCs). Smoke from three harm reduction brands was compared with smoke from a conventional brand. Doses of smoke were measured in puff equivalents (PE) (1 PE = the amount ... | ['Apoptosis', 'Cell Survival', 'Cells, Cultured', 'Colony-Forming Units Assay', 'Computational Biology', 'Embryonic Stem Cells', 'Harm Reduction', 'Humans', 'Image Processing, Computer-Assisted', 'Smoke', 'Tobacco', 'Tobacco Smoke Pollution', 'Video Recording'] | 20,702,591 | [['G04.146.954.035'], ['G04.346'], ['A11.251'], ['E01.370.225.500.383', 'E05.200.500.383', 'E05.242.383'], ['H01.158.273.180', 'L01.313.124'], ['A11.872.700.250'], ['F01.145.477'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['D20.633.937'], ['B01.650.940.800.575.912.250.908.500.900'], ['D20.633.9... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
alpha-Tocopherol attenuates alcohol-induced cerebral vascular damage in rats: possible role of oxidants in alcohol brain pathology and stroke. | Effects of chronic (14 day) pretreatment of timed-release of alpha-tocopherol (approximately 1.25-5 mg/day) on alcohol-induced venular cerebrovasospasm, microvessel rupture and micro-hemorrhaging was studied by direct, quantitative in-vivo high-resolution TV microscopy of the intact rat brain. Sham animals chronically ... | ['Animals', 'Brain Diseases', 'Central Nervous System Depressants', 'Cerebrovascular Circulation', 'Cerebrovascular Disorders', 'Drug Implants', 'Ethanol', 'Hypoxia, Brain', 'Ischemic Attack, Transient', 'Lipid Peroxidation', 'Male', 'Oxidants', 'Rats', 'Rats, Wistar', 'Vitamin E'] | 8,994,229 | [['B01.050'], ['C10.228.140'], ['D27.505.696.277', 'D27.505.954.427.210'], ['G09.330.100.159'], ['C10.228.140.300', 'C14.907.253'], ['D26.255.210.315'], ['D02.033.375'], ['C10.228.140.624', 'C23.888.852.079.797'], ['C10.228.140.300.150.836', 'C14.907.253.092.836'], ['G02.111.515', 'G03.295.531.587'], ['D27.720.642', 'D... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Screening and identification of a tumor specific methylation phenotype in the colorectal laterally spreading tumor. | OBJECTIVE: We screened and identified the differential expression of the methylation phenotype in the whole genome of colorectal laterally spreading tumor (LSTs).MATERIALS AND METHODS: 3 tissue samples of colorectal polypoid adenomas (PAs), 3 tissue samples of LSTs and 3 tissue samples of colon cancer were analyzed wit... | ['Adaptor Proteins, Signal Transducing', 'Adult', 'Aged', 'Cluster Analysis', 'Colorectal Neoplasms', 'DNA Methylation', 'Disease Progression', 'Female', 'Humans', 'Intestinal Polyps', 'Male', 'Middle Aged', 'Oligonucleotide Array Sequence Analysis', 'Phenotype', 'Polymerase Chain Reaction', 'Repressor Proteins', 'Tumo... | 28,678,324 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['G02.111.0... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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