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[Infective Endocarditis--Blood Culture and Echocardiography]. | Infective endocarditis (IE) is a systemic septic disease that is a microbial infection of the endothelial surface of the heart. Despite advances in medical, surgical, and critical care interventions, IE remains a life-threatening illness. Therefore, it is important to promptly diagnose it using the modified Duke criter... | ['Bacteremia', 'Echocardiography', 'Endocarditis, Bacterial', 'Fever', 'Humans', 'Practice Guidelines as Topic'] | 26,638,432 | [['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C01.150.252.245', 'C01.190.249', 'C14.260.249', 'C14.280.282.407'], ['C23.888.119.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.350.650', 'N05.700.350.650']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
One-year interim follow-up results of the TRAVERCE trial: the initial feasibility study for trans-apical aortic-valve implantation. | OBJECTIVES: To evaluate the interim results of the initial multicenter feasibility trial for trans-apical aortic-valve implantation (TA-AVI) in high-risk elderly patients with severe aortic stenosis.METHODS: A total of 168 patients were prospectively included in three European centers between February 2006 and April 20... | ['Aged', 'Aged, 80 and over', 'Aortic Valve', 'Aortic Valve Insufficiency', 'Aortic Valve Stenosis', 'Bioprosthesis', 'Catheterization', 'Echocardiography', 'Feasibility Studies', 'Female', 'Heart Valve Prosthesis', 'Heart Valve Prosthesis Implantation', 'Humans', 'Male', 'Prospective Studies', 'Treatment Outcome'] | 20,637,648 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A07.541.510.110'], ['C14.280.484.048.500'], ['C14.280.484.048.750', 'C14.280.955.249'], ['E07.695.100'], ['E02.148', 'E05.157'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The early cell kinetic response during healing of corneal epithelial wounds. | The labeling index and the mitotic rate were measured at 4-hour intervals during the first 24 hours after a central abrasion had been made in the corneal epithelium of six groups of four rats each. The proliferative response was noted in the conjunctival, the limbal, and the corneal epithelium. After 24 hours, the dens... | ['Animals', 'Cell Count', 'Cell Cycle', 'Cell Movement', 'Conjunctiva', 'Cornea', 'DNA Replication', 'Epithelium', 'Female', 'Limbus Corneae', 'Rats', 'Rats, Wistar', 'Wound Healing'] | 1,436,967 | [['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G04.144'], ['G04.198', 'G07.568.500.180'], ['A09.371.060.200', 'A09.371.337.168'], ['A09.371.060.217'], ['G02.111.225', 'G05.226'], ['A10.272'], ['A09.371.060.217.659'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preclinical and clinical evidence that Deoxy-2-[18F]fluoro-D-glucose positron emission tomography with computed tomography is a reliable tool for the detection of early molecular responses to erlotinib in head and neck cancer. | PURPOSE: There is a clinical need to identify predictive markers of the responses to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKI). Deoxy-2-[(18)F]fluoro-d-glucose positron emission tomography with computed tomography ((18)FDG-PET/CT) could be a tool of choice for monitoring the early effects o... | ['Aged', 'Animals', 'Blotting, Western', 'Cell Line, Tumor', 'Erlotinib Hydrochloride', 'Female', 'Fluorescent Antibody Technique', 'Fluorodeoxyglucose F18', 'Head and Neck Neoplasms', 'Humans', 'Male', 'Mice', 'Mice, Nude', 'Middle Aged', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated Protein Kinase 3', 'Pho... | 20,660,574 | [['M01.060.116.100'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210.190', 'A11.251.860.180'], ['D03.633.100.786.375'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Heparin-stimulated expression of extracellular-superoxide dismutase in human fibroblasts. | Extracellular-superoxide dismutase (EC-SOD) is the major SOD isozyme in the arterial wall and may be important for antioxidation capability of the vascular wall and normal vascular function. EC-SOD is expressed in various cell types in the vascular wall such as fibroblasts, smooth muscle cells and macrophages, and the ... | ['Base Sequence', 'Cells, Cultured', 'Enzyme-Linked Immunosorbent Assay', 'Fibroblasts', 'Heparin', 'Humans', 'Molecular Sequence Data', 'Probability', 'RNA', 'RNA, Messenger', 'Sensitivity and Specificity', 'Superoxide Dismutase'] | 11,730,810 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['A11.329.228'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['E05.318.740.600', 'G... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[A prospective randomized and controlled study on no drainage after surgery for benign thyroid disorders]. | OBJECTIVE: To evaluate the necessity of drainage after thyroidectomy for benign thyroid disorders.METHODS: A total of 272 patients who underwent thyroidectomy for benign thyroid disorders were randomly divided into drainage group or non-drainage group. Operating time, postoperative stay time in hospital, comfort of nec... | ['Body Fluids', 'Drainage', 'Female', 'Hematoma', 'Hoarseness', 'Humans', 'Hypoparathyroidism', 'Male', 'Neck', 'Neck Dissection', 'Pain Measurement', 'Postoperative Complications', 'Postoperative Period', 'Prospective Studies', 'Thyroid Diseases', 'Thyroidectomy'] | 24,195,823 | [['A12.207'], ['E02.309', 'E04.237'], ['C23.550.414.838'], ['C08.360.940.490', 'C08.618.490', 'C09.400.940.490', 'C10.597.975.550', 'C23.888.592.979.550', 'C23.888.852.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.642.482'], ['A01.598'], ['E04.446.318', 'E04.580.411'], ['E01.370.600.550.324'], ['C23.550... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Gait Phase Identification During Level, Incline and Decline Ambulation Tasks Using Portable Sonomyographic Sensing. | Clinical viability of powered lower-limb assistive devices requires reliable and intuitive control strategies. Stance and swing are the main phases of the gait cycle across different locomotion tasks. Hence, a reliable method to accurately identify these phases can decrease sensing complexity and assist in enabling hig... | ['Adult', 'Algorithms', 'Female', 'Gait', 'Humans', 'Locomotion', 'Lower Extremity', 'Male', 'Muscle, Skeletal', 'Support Vector Machine', 'Walking', 'Young Adult'] | 31,374,758 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568.500', 'G11.427.410.568'], ['A01.378.610'], ['A02.633.567', 'A10.690.552.500'], ['G17.035.250.500.500.500', 'L01.224.050.375.530.500.500'], ['G11.427.410.568.900', 'G11... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 |
MyoD targets TAF3/TRF3 to activate myogenin transcription. | Skeletal muscle differentiation requires a cascade of transcriptional events to control the spatial and temporal expression of muscle-specific genes. Until recently, muscle-specific transcription was primarily attributed to prototypic enhancer-binding factors, while the role of core promoter recognition complexes in di... | ['Animals', 'Cell Line', 'Homeodomain Proteins', 'In Vitro Techniques', 'Mice', 'Multiprotein Complexes', 'Muscle Fibers, Skeletal', 'MyoD Protein', 'Myogenin', 'Promoter Regions, Genetic', 'Protein Structure, Tertiary', 'Protein Subunits', 'Recombinant Proteins', 'TATA Box Binding Protein-Like Proteins', 'TATA-Binding... | 18,851,836 | [['B01.050'], ['A11.251.210'], ['D12.776.260.400'], ['E05.481'], ['B01.050.150.900.649.313.992.635.505.500'], ['D05.500'], ['A10.690.552.500.500', 'A11.620.249'], ['D12.776.210.500.570.590', 'D12.776.260.103.750.590', 'D12.776.930.125.750.590'], ['D12.776.210.500.570.600', 'D12.776.260.103.750.600', 'D12.776.930.125.75... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Cdc14B phosphatase contributes to ciliogenesis in zebrafish. | Progression through the cell cycle relies on oscillation of cyclin-dependent kinase (Cdk) activity. One mechanism for downregulating Cdk signaling is to activate opposing phosphatases. The Cdc14 family of phosphatases counteracts Cdk1 phosphorylation in diverse organisms to allow proper exit from mitosis and cytokinesi... | ['Amino Acid Sequence', 'Animals', 'Animals, Genetically Modified', 'Base Sequence', 'Body Patterning', 'Cell Cycle Proteins', 'Cell Division', 'Cilia', 'Cloning, Molecular', 'Dual-Specificity Phosphatases', 'Gene Expression Regulation, Developmental', 'Gene Expression Regulation, Enzymologic', 'Gene Knockdown Techniqu... | 21,177,342 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G07.345.500.100'], ['D12.776.167'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.284.180.165'], ['E05.393.220'], ['D08.811.277.352... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Relationship of hospital organizational culture to patient safety climate in the Veterans Health Administration. | Improving safety climate could enhance patient safety, yet little evidence exists regarding the relationship between hospital characteristics and safety climate. This study assessed the relationship between hospitals' organizational culture and safety climate in Veterans Health Administration (VA) hospitals nationally.... | ['Adolescent', 'Adult', 'Female', 'Health Care Surveys', 'Humans', 'Male', 'Medical Errors', 'Middle Aged', 'Organizational Culture', 'Safety Management', 'United States', 'United States Department of Veterans Affairs', 'Young Adult'] | 19,244,094 | [['M01.060.057'], ['M01.060.116'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.450'], ['M01.060.116.630'], ['N04.452.606'], ['N04.452.871.900', 'N06.850.135.060.075.800'], ['Z01.107.567.875'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Can the short index of problems (SIP) be improved? Validity and reliability of the three-month SIP in an emergency department sample. | OBJECTIVE: Although the Short Index of Problems (SIP) is often used, little is known about the psychometric properties of the SIP in special populations. The present study seeks to determine the following: (1) whether it is possible to substitute items to enhance the psychometric properties of the SIP and (2) whether t... | ['Adult', 'Alcoholism', 'Emergency Medical Services', 'Female', 'Humans', 'Male', 'Psychometrics', 'Reproducibility of Results', 'Surveys and Questionnaires', 'Wounds and Injuries'] | 16,047,535 | [['M01.060.116'], ['C25.775.100.250', 'F03.900.100.350'], ['N02.421.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['C26']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Cryotherapy for primary and secondary liver tumours]. | AIMS: We assessed the morbidity, mortality and efficacy of cryotherapy for primary and secondary malignant liver tumours in a prospective case control study.METHODS: Since 1996 we performed 77 cryosurgical procedures on 71 patients. 6 patients had hepatocellular carcinoma, the remainders metastases, mainly of colorecta... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Hepatocellular', 'Colorectal Neoplasms', 'Cryosurgery', 'Female', 'Follow-Up Studies', 'Germany', 'Hospital Mortality', 'Humans', 'Liver', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Reoperation', 'Survival Rate', 'Tomography, X-Ray Compute... | 12,085,275 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E04.014.180'], ['E05... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Guidelines for nonclinical toxicology studies for chemical warfare agent (CWA) antidotes and pretreatments. | The following is a review of FDA's guidelines for nonclinical toxicology studies as applied to chemical warfare agent (CWA) antidotes and pretreatments. These specific guidelines are of major interest to the U.S. Army Medical Research and Development Command which is a full-scale developer of pharmaceuticals and active... | ['Antidotes', 'Chemical Warfare', 'United States', 'United States Food and Drug Administration'] | 3,238,065 | [['D27.505.696.706.037', 'D27.720.799.037'], ['I01.880.735.950.500.340'], ['Z01.107.567.875'], ['I01.409.418.750.600.650.760', 'N03.540.348.500.500.600.650.760']] | ['Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Simple and Procedural Reaction Time for Mild Traumatic Brain Injury in a Hyperbaric Oxygen Clinical Trial. | Simple reaction time (SRT) and procedural reaction time (PRT) are speed-of-processing tasks in the Automated Neuropsychological Assessment Metrics (ANAM) that may be sensitive to mild traumatic brain injury (mTBI). The investigators measured SRT and PRT throughput (correct responses per minute) at baseline, 6 weeks, an... | ['Adult', 'Brain Concussion', 'Brain Injuries', 'Cognitive Dysfunction', 'Female', 'Humans', 'Hyperbaric Oxygenation', 'Male', 'Middle Aged', 'Military Personnel', 'Neuropsychological Tests', 'Oxygen', 'Reaction Time'] | 27,168,551 | [['M01.060.116'], ['C10.228.140.199.444.250', 'C10.900.300.087.235.250', 'C10.900.300.350.300', 'C26.915.300.200.194.250', 'C26.915.300.450.500', 'C26.974.382.200'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['F03.615.250.700'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.880.690.490'], ['M0... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Iterative reconstruction for helical CT: a simulation study. | Iterative reconstruction algorithms for helical CT are presented. The algorithms are derived from two-dimensional reconstruction algorithms, by adapting the projector/backprojector to the helical orbit of the source, and by constraining the axial frequencies with a Gaussian sieve. Simulations have been carried out and ... | ['Algorithms', 'Artifacts', 'Calibration', 'Computer Simulation', 'Humans', 'Image Processing, Computer-Assisted', 'Likelihood Functions', 'Phantoms, Imaging', 'Tomography, X-Ray Computed'] | 9,572,499 | [['G17.035', 'L01.224.050'], ['E05.047'], ['E05.978.155'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.360.750.625.450', 'N06.850.520.830.500.475', 'N06.850.520.830.600.400'], ['E... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Complications after implantation of a new-generation insertable cardiac monitor: Results from the LOOP study. | BACKGROUND: Insertable cardiac monitors (ICM) are leadless devices utilized in long-term monitoring of the heart rhythm. The implantation procedure of the new-generation ICMs is minimally invasive, but little experience exists regarding complications. We thus aimed to investigate adverse events (AE) according to proced... | ['Aged', 'Aged, 80 and over', 'Arrhythmias, Cardiac', 'Electrocardiography, Ambulatory', 'Female', 'Follow-Up Studies', 'Hemorrhage', 'Humans', 'Male', 'Miniaturization', 'Pain', 'Prospective Studies', 'Prostheses and Implants', 'Stroke'] | 28,457,562 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.067', 'C23.550.073'], ['E01.370.370.380.240.230', 'E01.370.405.240.230', 'E01.370.520.500.230'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.897... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Distress, sleep difficulty, and fatigue in women co-infected with HIV and HPV. | Women with HIV infection report elevated and persisting psychosocial distress, sleep difficulty, and fatigue. The objective of this study was to examine psychosocial distress, sleep difficulty, and fatigue in a group of lower socioeconomic status women co-infected with HIV and HPV (N = 60). After controlling for releva... | ['Adolescent', 'Adult', 'Fatigue', 'Female', 'HIV Infections', 'Humans', 'Middle Aged', 'Models, Statistical', 'Papillomavirus Infections', 'Psychiatric Status Rating Scales', 'Sleep Wake Disorders', 'Stress, Psychological'] | 19,568,967 | [['M01.060.057'], ['M01.060.116'], ['C23.888.369'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Nonpeptide ligands for human gamma delta T cells. | gamma delta T cells respond to a variety of microbial pathogens and transformed cells. Their limited receptor repertoire and activation by mycobacterial antigens resistant to proteases suggest that they may recognize nonpeptide antigens. We have tested a variety of nonpeptide molecules for stimulation of human gamma de... | ['Antibodies', 'Antigens, Bacterial', 'Arthritis, Rheumatoid', 'Clone Cells', 'Cytotoxicity, Immunologic', 'Flow Cytometry', 'Humans', 'Ligands', 'Lymphocyte Activation', 'Mycobacterium tuberculosis', 'Organophosphates', 'Receptors, Antigen, T-Cell, gamma-delta', 'Synovial Fluid', 'T-Lymphocytes'] | 8,058,775 | [['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D23.050.161'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['A11.251.353'], ['G12.287'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.5... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modulation of the sympathetic nerve action on carbohydrate and ketone body metabolism by fatty acids, glucagon und insulin in perfused rat liver. | Rat liver was perfused in situ via the portal vein without recirculation: 1) Nerve stimulation (20 Hz, 2 ms, 20 V) increased glucose output and shifted lactate uptake to output; the alterations were diminished by oleate but not octanoate. 2) Glucagon (1nM) stimulated glucose output maximally also in the presence of the... | ['Animals', 'Caprylates', 'Carbohydrate Metabolism', 'Electric Stimulation', 'Fatty Acids', 'Glucagon', 'Glucose', 'Insulin', 'Ketone Bodies', 'Lactates', 'Lactic Acid', 'Liver', 'Male', 'Oleic Acid', 'Oleic Acids', 'Pyruvates', 'Pyruvic Acid', 'Rats', 'Rats, Inbred Strains', 'Sympathetic Nervous System'] | 2,692,615 | [['B01.050'], ['D02.241.081.222', 'D10.251.122'], ['G02.111.158', 'G03.191'], ['E05.723.402'], ['D10.251'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['D09.947.875.359.448'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D02.522.585'], ['D02.241.511.459'], ['D02.241.511.459.450'], ['A0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human intestinal glutathione S-transferases. | Cytosolic glutathione S-transferases were purified from the epithelial cells of human small and large intestine. These preparations were characterized with regard to specific activities, subunit and isoenzyme composition. Isoenzyme composition and specific activity showed little variation from proximal to distal small ... | ['Adult', 'Age Factors', 'Aged', 'Cytosol', 'Electrophoresis, Polyacrylamide Gel', 'Epithelium', 'Female', 'Glutathione Transferase', 'Humans', 'Intestinal Mucosa', 'Intestine, Large', 'Intestine, Small', 'Isoelectric Focusing', 'Liver', 'Male', 'Middle Aged'] | 2,930,461 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['E05.196.401.402', 'E05.301.300.319'], ['A10.272'], ['D08.811.913.225.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.369', 'A10.615.550.444'], ['A... | ['Named Groups [M]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Changes in bacterial community during fermentative hydrogen and acid production from organic waste by thermophilic anaerobic microflora. | AIMS: Changes in fermentation pattern during the treatment of organic wastes containing solid materials by thermophilic anaerobic microflora were investigated with respect to product formation and bacterial community structure during hydrogen production.METHODS AND RESULTS: Anaerobic microflora enriched from sludge com... | ['Acids', 'Bacteria', 'Base Sequence', 'Biomass', 'Bioreactors', 'DNA, Bacterial', 'Energy-Generating Resources', 'Fermentation', 'Gene Library', 'Hydrogen', 'Hydrogen-Ion Concentration', 'Molecular Sequence Data', 'Polymorphism, Restriction Fragment Length', 'Principal Component Analysis', 'RNA, Ribosomal, 16S', 'Sewa... | 16,882,140 | [['D01.029'], ['B03'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G16.500.275.157.100', 'N06.230.124.100'], ['E07.115', 'J01.897.120.115'], ['D13.444.308.212'], ['N06.230.132'], ['G02.111.158.249', 'G03.191.249'], ['G05.360.325'], ['D01.268.406', 'D01.362.340'], ['G02.300'], ['L01.453.245.667'], ['G05... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Usefulness of two instruments in assessing depression among elderly Mexicans in population studies and for primary care. | OBJECTIVE: To determine the psychometric qualities of the CES-DR and GDS scales in the elderly and compare them to clinical psychiatric diagnoses.MATERIAL AND METHODS: The first phase consisted of home interviews for determining the psychometric qualities of the GDS and CES-DR scales. In the second phase, psychiatrists... | ['Aged', 'Aged, 80 and over', 'Depression', 'Depressive Disorder', 'Female', 'Health Personnel', 'Humans', 'Interview, Psychological', 'Interviews as Topic', 'Male', 'Mexico', 'Middle Aged', 'Observer Variation', 'Population Surveillance', 'Primary Health Care', 'Psychiatric Status Rating Scales', 'Psychiatry', 'Sampli... | 19,039,433 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.145.126.350'], ['F03.600.300'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.669.599'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['Z01.107.567.589'], ['M01.060.116.630'], ['E01.354.753... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Soc... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
High speed two-dimensional protein separation without gel by isoelectric focusing-asymmetrical flow field flow fractionation: application to urinary proteome. | An online multilane channel system for isoelectric focusing and asymmetrical flow field-flow fractionation (IEF-AF4) is utilized for the two-dimensional separation (2D: isoelectric point, pI, and hydrodynamic diameter, d(s)) of a human proteome sample followed by the shotgun proteomic analysis using nanoflow liquid chr... | ['Fractionation, Field Flow', 'Humans', 'Hydrogen-Ion Concentration', 'Isoelectric Focusing', 'Peptide Fragments', 'Peptide Mapping', 'Proteins', 'Proteinuria', 'Proteome', 'Proteomics', 'Tandem Mass Spectrometry'] | 19,653,698 | [['E05.196.155.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E05.196.401.663', 'E05.301.300.663'], ['D12.644.541'], ['E05.196.181.400.454.720', 'E05.196.401.319.720', 'E05.196.700', 'E05.393.760.705.685'], ['D12.776'], ['C12.777.934.734', 'C13.351.968.934.734', 'C23.888.942.750'], ['D12.776.817... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparing classifications of death in the Mode Selection Trial: agreement and disagreement among site investigators and a clinical events committee. | Clinical events committees (CECs) are the current standard for endpoint adjudication in clinical trials. However, little data exist with which to compare CEC and site investigator determinations or to evaluate internal agreement among CEC members. Using data from the Mode Selection Trial in Sinus Node Dysfunction (MOST... | ['Cause of Death', 'Clinical Trials Data Monitoring Committees', 'Clinical Trials as Topic', 'Decision Making', 'Humans', 'Interdisciplinary Communication', 'Observer Variation', 'Outcome Assessment, Health Care', 'Peer Review', 'Research Personnel'] | 16,574,497 | [['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['N05.700.685.149'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205.249', 'L01.143.86... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Dog bite injuries to children: potential rabies threat to Australia. | A consecutive series of 800 mammalian bites is reported from The Canberra Hospital. Of these, 66% were dog bites; 119 children were bitten by dogs (requiring hospital attention) over a 30-month period, giving an average dog-bite rate for the total population of 184 per 100,000 per year. One dog in 38 causes an injury r... | ['Animals', 'Australia', 'Bites and Stings', 'Child', 'Child, Preschool', 'Dogs', 'Humans', 'Infant', 'Infant, Newborn', 'Rabies', 'Risk'] | 7,189,574 | [['B01.050'], ['Z01.639.100', 'Z01.678.100.373'], ['C25.723.127', 'C26.176'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C01.925.782.580.830.750'], ['E05.318.740.600.800', 'G17.680.750', 'N05... | ['Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Magnetic Resonance Image Texture Analysis of the Periaqueductal Gray Matter in Episodic Migraine Patients without T2-Visible Lesions. | Objective: The periaqueductal gray matter (PAG), a small midbrain structure, presents dysfunction in migraine. However, the precise neurological mechanism is still not well understood. Herein, the aim of this study was to investigate the texture characteristics of altered PAG in episodic migraine (EM) patients based on... | ['Adult', 'Analysis of Variance', 'Area Under Curve', 'Brain', 'Case-Control Studies', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Migraine Disorders', 'Periaqueductal Gray', 'ROC Curve'] | 29,354,004 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['A08.186.211'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.30... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The influence of oxygen tension on theophylline clearance in the rat isolated perfused liver. | The effect of changes in the rate of perfusion and oxygen tension (PO2) on theophylline clearance was determined in the rat isolated perfused liver. Changes in rate of perfusion had no effect on the extraction ratio of theophylline while a decrease in the PO2 significantly increased the half life of theophylline. These... | ['Animals', 'Half-Life', 'In Vitro Techniques', 'Kinetics', 'Liver', 'Male', 'Oxygen', 'Partial Pressure', 'Perfusion', 'Rats', 'Rats, Inbred Strains', 'Theophylline'] | 2,871,166 | [['B01.050'], ['G01.910.405'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['A03.620'], ['D01.268.185.550', 'D01.362.670'], ['G01.374.715.714'], ['E05.680'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D03.132.960.751', 'D03.633.100.759.758... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tailored (meth)acrylate shape-memory polymer networks for ophthalmic applications. | The unique features of shape-memory polymers enables their use in minimally invasive surgical procedures with a compact starting material switching over to a voluminous structure in vivo. In this work, a series of transparent, thermoset (meth)acrylate shape-memory polymer networks with tailored thermomechanics have bee... | ['Biocompatible Materials', 'Cross-Linking Reagents', 'Elasticity', 'Humans', 'Materials Testing', 'Methacrylates', 'Ophthalmology', 'Polymers', 'Stress, Mechanical', 'Temperature', 'Transition Temperature'] | 20,625,994 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D27.720.470.410.210'], ['G01.374.590'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.570'], ['D02.241.081.069.600'], ['H02.403.810.468'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['G01.374.835'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.77... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Spiegel's lobe bile ducts often drain into the right hepatic duct or its branches: study using drip-infusion cholangiography-computed tomography in 179 consecutive patients. | Using drip-infusion cholangiography-computed tomography (DIC-CT), we successfully identified the bile ducts draining the caudate lobe in 138 of 179 consecutive patients with extrahepatic cholelithiasis (179 ducts from Spiegel's lobe and 154 from the paracaval portion; 1-5 ducts per patient). The dorsal subsegmental duc... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bile Ducts, Intrahepatic', 'Cholangiography', 'Female', 'Hepatic Duct, Common', 'Humans', 'Male', 'Middle Aged', 'Tomography, X-Ray Computed'] | 15,573,255 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['A03.159.183.158', 'A03.620.150'], ['E01.370.350.700.715.200', 'E01.370.372.200'], ['A03.159.183.079.600'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Tyrosine oxidation in heme oxygenase: examination of long-range proton-coupled electron transfer. | Heme oxygenase is responsible for the degradation of a histidine-ligated ferric protoporphyrin IX (Por) to biliverdin, CO, and the free ferrous ion. Described here are studies of tyrosyl radical formation reactions that occur after oxidizing Fe(III)(Por) to Fe(IV)=O(Por(·+)) in human heme oxygenase isoform-1 (hHO-1) an... | ['Amino Acid Sequence', 'Corynebacterium diphtheriae', 'Electron Transport', 'Heme Oxygenase (Decyclizing)', 'Humans', 'Models, Molecular', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Oxidation-Reduction', 'Protons', 'Sequence Alignment', 'Tyrosine'] | 25,023,856 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B03.510.024.250.150', 'B03.510.460.400.400.200.150'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['D08.811.682.690.708.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595'], ['L01.453.245.667'], ['E05.393.420.601.575'], ['G02.700', 'G03.295.531'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Analysis of hydroxyproline by high performance liquid chromatography and its application to collagen turnover studies in bone cultures. | We describe a high performance liquid chromatography (HPLC) technique for separating and quantitating hydroxyproline in calvarial cultures. Using a reverse-phase Nova-Pak C18 column and a 140 mM sodium acetate, 0.05% triethylamine (TEA), 6% acetonitrile solvent system, we obtained a complete separation of hydroxyprolin... | ['Animals', 'Bone and Bones', 'Cells, Cultured', 'Chromatography, High Pressure Liquid', 'Collagen', 'Hydroxyproline', 'Parathyroid Hormone', 'Rats', 'Skull', 'Tritium'] | 2,504,455 | [['B01.050'], ['A02.835.232', 'A10.165.265'], ['A11.251'], ['E05.196.181.400.300'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D12.125.072.401.623.478'], ['D06.472.699.590', 'D12.644.548.587'], ['B01.050.150.900.649.313.992.635.505.700'], ['A02.835.232.781'], ['D01.268.406.875', 'D01.362.340.875', 'D01.496.749.925']... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term validation of 1 g of protein per kilogram body weight from a predominantly vegetable mixed diet to meet the requirements of young adult males. | Eight healthy young men participated in a 90-d metabolic balance study designed to assess the adequacy of 1 g of protein (N X 6.25) per kilogram body weight per day provided by a predominantly vegetable diet. The mean gross energy intake of the subjects was 49 kcal/(kg X d). The individuals received the experimental di... | ['Adult', 'Analysis of Variance', 'Anthropometry', 'Creatinine', 'Diet, Vegetarian', 'Dietary Proteins', 'Energy Intake', 'Feces', 'Humans', 'Male', 'Nitrogen', 'Nutritional Requirements'] | 3,701,462 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['D03.383.129.308.207'], ['E02.642.249.300', 'G07.203.650.240.300'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.650.240.340'], ['A12.459'], ['B01.050.150.900.649.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Elderly patients presenting to a Level I trauma center with Physician Orders for a Life-Sustaining Treatment form: A propensity-matched analysis. | BACKGROUND: Physician Orders for Life-Sustaining Treatment (POLST) forms are portable medical orders documenting patient treatment preferences in an acute health decline. It is unclear how these forms are used in the management of elderly trauma patients.METHODS: Patients 65 years and older presenting to a Level I trau... | ['Advance Directives', 'Aged', 'Aged, 80 and over', 'Female', 'Hospital Mortality', 'Humans', 'Intensive Care Units', 'Length of Stay', 'Male', 'Propensity Score', 'Resuscitation Orders', 'Retrospective Studies', 'Trauma Centers', 'Treatment Outcome', 'Wounds and Injuries'] | 31,033,897 | [['I01.880.604.583.020', 'N03.706.535.020', 'N04.590.233.624.124.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['E02.760.400.480'... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Choice reaction time performance correlates with diffusion anisotropy in white matter pathways supporting visuospatial attention. | Humans exhibit significant interindividual variability in behavioral reaction time (RT) performance yet the underlying neural mechanisms for this variability remain largely unknown. It has been proposed that interindividual variability in RT performance may be due to differences in white matter (WM) physiological prope... | ['Adult', 'Anisotropy', 'Attention', 'Brain', 'Choice Behavior', 'Cluster Analysis', 'Diffusion Magnetic Resonance Imaging', 'Female', 'Functional Laterality', 'Humans', 'Male', 'Massachusetts', 'Neural Pathways', 'Psychomotor Performance', 'Reaction Time'] | 16,103,359 | [['M01.060.116'], ['G01.590.040', 'G02.050'], ['F02.830.104.214'], ['A08.186.211'], ['F02.463.785.373.346'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E01.370.350.825.500.150'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.550.510'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Tg737 signaling is required for hypoxia-enhanced invasion and migration of hepatoma cells. | BACKGROUND: Although hypoxia is known to promote hepatoma cell invasion and migration, little is known regarding the molecular mechanisms of this process. Our previous research showed that loss of Tg737 is associated with hepatoma cell invasion and migration; therefore, we hypothesized that the Tg737 signal might be re... | ['Carcinoma, Hepatocellular', 'Cell Hypoxia', 'Cell Movement', 'Cell Survival', 'Gene Expression Regulation, Neoplastic', 'Hep G2 Cells', 'Humans', 'Interleukin-8', 'Neoplasm Invasiveness', 'Signal Transduction', 'TRPP Cation Channels', 'Transforming Growth Factor beta1', 'Tumor Suppressor Proteins'] | 22,974,282 | [['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G03.197.300', 'G04.270.300'], ['G04.198', 'G07.568.500.180'], ['G04.346'], ['G05.308.370'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.200.120.800', 'D12.644.2... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of 5-year oncological outcomes of breast cancer based on surgery type. | BACKGROUND: A standardized classification system for breast surgery that incorporates oncoplastic techniques is needed. We classified the surgical techniques for breast cancer treatment into five groups according to the extent of surgery and reconstructive methods, i.e. conventional breast-conserving surgery, partial m... | ['Adult', 'Aged', 'Breast Neoplasms', 'Carcinoma', 'Female', 'Humans', 'Mammaplasty', 'Mastectomy', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Retrospective Studies', 'Survival Rate', 'Time Factors', 'Treatment Outcome'] | 28,544,393 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.218.565', 'E04.680.500'], ['E04.466'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.5... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
PAIN ASSOCIATED WITH LIVER BIOPSIES THROUGH PERCUTANEOUS APPROACH UNDER SONO-GRAPHIC GUIDANCE--A CROSS SECTIONAL PILOT STUDY IN A TERTIARY CARE HOSPITAL. | BACKGROUND: Pain is one of the most common and feared complication of percutaneous liver biopsy under local anaesthesia using sonographic guidance. This observational study was set to judge the intensity of pain felt by adult patients presenting for percutaneous liver biopsy with known/suspected underlying hepatic path... | ['Adolescent', 'Adult', 'Cross-Sectional Studies', 'Female', 'Humans', 'Image-Guided Biopsy', 'Incidence', 'Liver', 'Liver Diseases', 'Male', 'Middle Aged', 'Pain', 'Pain Measurement', 'Pakistan', 'Pilot Projects', 'Tertiary Care Centers', 'Visual Analog Scale', 'Young Adult'] | 26,182,735 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.384.100.370', 'E01.370.225.998.054.370', 'E01.370.388.100.370', 'E04.074.370', 'E05.200.500.384.100.370', 'E05.200.998.054.370', 'E05.242.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Fast parsers for Entrez Gene. | NCBI completed the transition of its main genome annotation database from Locuslink to Entrez Gene in Spring 2005. However, to this date few parsers exist for the Entrez Gene annotation file. Owing to the widespread use of Locuslink and the popularity of Perl programming language in bioinformatics, a publicly available... | ['Algorithms', 'Database Management Systems', 'Databases, Genetic', 'Information Storage and Retrieval', 'Natural Language Processing', 'Software', 'User-Computer Interface', 'Vocabulary, Controlled'] | 15,879,451 | [['G17.035', 'L01.224.050'], ['L01.224.068', 'L01.224.900.280', 'N04.452.515.110'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['L01.313.500.750.280', 'L01.470'], ['L01.224.050.375.580'], ['L01.224.900'], ['L01.224.900.910'], ['L01.453.245.945']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Identification of catalytic amino acids in the human GTP fucose pyrophosphorylase active site. | GTP-l-fucose pyrophosphorylase(GFPP) catalyzes the reversible formation of the nucleotide-sugar GDP-beta-l-fucose from guanosine triphosphate and beta-l-fucose-1-phosphate. The enzyme functions primarily in the mammalian liver and kidney to salvage free fucose during the breakdown of glycoproteins and glycolipids. GFPP... | ['Amino Acids', 'Catalysis', 'Catalytic Domain', 'Conserved Sequence', 'Humans', 'Lysine', 'Mutagenesis, Site-Directed', 'Nucleotidyltransferases'] | 16,185,085 | [['D12.125'], ['G02.130'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['G02.111.570.580'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['E05.393.420.601.575'], ['D08.811.913.696.445']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The shape of red blood cells as a function of membrane potential and temperature. | It is well known that a pH shift of the outside medium from 5 to 9 produces a shape transformation of washed human red blood cells from stomatocytes to echinocytes in isotonic salt solutions. In addition, a stomatocytogenic effect is demonstrated here due to solutions of low ionic strength (below 70 mM). An analysis of... | ['Amphotericin B', 'Cell Membrane Permeability', 'Erythrocyte Membrane', 'Erythrocytes', 'Humans', 'Hydrogen-Ion Concentration', 'Membrane Potentials', 'Osmolar Concentration', 'Sodium Chloride', 'Temperature'] | 43,897 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Action profiles of statins and calcineurin inhibitors during human mixed lymphocyte reaction. | The cell-to-cell interaction through binding intercellular adhesion molecule (ICAM)-1 and CD40 on monocytes and their ligands such as lymphocyte function-associated antigen (LFA)-1 and CD40 ligand (CD40L) on T-cells plays roles in cytokine production and T-cell proliferation. Interleukin (IL)-18, which is elevated in t... | ['CD40 Antigens', 'Calcineurin Inhibitors', 'Cell Proliferation', 'Cyclosporine', 'Fatty Acids, Monounsaturated', 'Fluvastatin', 'Humans', 'Hydroxymethylglutaryl CoA Reductases', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Immunosuppressive Agents', 'Indoles', 'Intercellular Adhesion Molecule-1', 'Interferon-gam... | 17,482,516 | [['D12.776.465.750', 'D12.776.543.750.705.852.760.097', 'D23.050.301.264.051.140', 'D23.101.100.150.140'], ['D27.505.519.389.174'], ['G04.161.750', 'G07.345.249.410.750'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['D10.251.355.325'], ['D03.633.100.473.305', 'D10.251.450.300'], ['B01.050.150.900.649.313.988.400.1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Reconstruction of the oral cavity: the free radial forearm flap versus the free jejunal flap]. | The concentration in a restricted area such as the oral cavity of the essential anatomic structures for mastication, deglutition, speech, salivary drainage and respiration makes it indispensable to ensure not only the structural reconstruction of the region but also, and above all, a functional reconstruction of the an... | ['Adult', 'Aged', 'Chemotherapy, Adjuvant', 'Female', 'Follow-Up Studies', 'Forearm', 'Humans', 'Jejunum', 'Male', 'Microsurgery', 'Middle Aged', 'Mouth', 'Mouth Neoplasms', 'Surgical Flaps'] | 7,476,775 | [['M01.060.116'], ['M01.060.116.100'], ['E02.186.170', 'E02.319.170'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A01.378.800.585'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684.500', 'A03.556.249.750'], ['E04.494', 'E05.591.580'], ['M01.060.116.63... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
High dose oral tolerance in ovalbumin TCR-transgenic mice: systemic neutralization of IL-12 augments TGF-beta secretion and T cell apoptosis. | The immune response to oral Ag administration, including the development of oral tolerance, was explored with the use of OVA TCR-transgenic mice. Feeding high doses of OVA enhanced IFN-gamma production in the Peyer's patches, but induced tolerance in the peripheral lymphoid tissues marked by suppressed proliferative an... | ['Administration, Oral', 'Animals', 'Antibodies', 'Apoptosis', 'Dose-Response Relationship, Immunologic', 'Epitopes', 'Female', 'Immune Tolerance', 'Injections, Intravenous', 'Interferon-gamma', 'Interleukin-12', 'Lymphocyte Activation', 'Mice', 'Mice, Inbred BALB C', 'Mice, Transgenic', 'Ovalbumin', "Peyer's Patches",... | 8,805,632 | [['E02.319.267.100'], ['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['G04.146.954.035'], ['G12.300'], ['D23.050.550'], ['G12.535.425'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Plasma fibrinogen levels are associated with a strong family history of myocardial infarction. | Family history of myocardial infarction (MI) is a known risk factor for coronary artery disease (CAD). The aim of the present study was to investigate whether there is a specific risk factor profile for CAD in individuals with a strong family history of MI occurring at any age. The Study of Health in Pomerania is a cro... | ['Adult', 'Aged', 'Aged, 80 and over', 'Angina Pectoris', 'Apolipoprotein A-I', 'Case-Control Studies', 'Comorbidity', 'Coronary Disease', 'Cross-Sectional Studies', 'Female', 'Fibrinogen', 'Genetic Predisposition to Disease', 'Germany', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Parents', 'Risk Factors... | 15,311,159 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.647.187', 'C14.907.585.187', 'C23.888.592.612.233.500'], ['D10.532.091.200.100', 'D12.776.070.400.200.100', 'D12.776.521.120.200.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['N05.715.350.225', 'N06.850.49... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Acute phase reactants in patients with abdominal aortic aneurysm. | BACKGROUND: There is increasing evidence that an inflammatory process is present in abdominal aortic aneurysms (AAAs) to varying degrees. The aim of this study was to compare acute phase reactants in patients with asymptomatic AAA, symptomatic AAA without rupture and ruptured AAA.METHOD: Two hundred and twenty-five con... | ['Acute-Phase Proteins', 'Acute-Phase Reaction', 'Aged', 'Aortic Aneurysm, Abdominal', 'Aortic Rupture', 'Biomarkers', 'C-Reactive Protein', 'Case-Control Studies', 'Female', 'Humans', 'Leukocyte Count', 'Logistic Models', 'Male'] | 12,052,476 | [['D12.776.124.050'], ['C23.550.470.099'], ['M01.060.116.100'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['C14.907.055.185.125', 'C14.907.055.239.175', 'C14.907.109.139.175', 'C26.761.125'], ['D23.101'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E05.318.372.500.500', 'N05.715.360.330.5... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Information Processing in the Mental Workspace Is Fundamentally Distributed. | The brain is a complex, interconnected information processing network. In humans, this network supports a mental workspace that enables high-level abilities such as scientific and artistic creativity. Do the component processes underlying these abilities occur in discrete anatomical modules, or are they distributed wid... | ['Adolescent', 'Adult', 'Brain', 'Female', 'Humans', 'Imagination', 'Information Theory', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neuropsychological Tests', 'Photic Stimulation', 'Rotation', 'Signal Processing, Computer-Assisted', 'Visual Perception', 'Young Adult'] | 26,488,589 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.188.634'], ['L01.488'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['F04.711.513'], ['E05.723.729'], ['G01.482.703'], ['L01.224... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Urothelial cancer metastases after implantation of tumor cells under the kidney capsule]. | In this study we used the subrenal capsule site of C57BL/6J mice to assess the tumorigenic and metastatic potential of established urothelial cell lines in a syngeneic murine model. High tumor take and subsequent removal of the primary tumor by nephrectomy resulted in the extended lifespan of the animals enabling the f... | ['Animals', 'Carcinoma, Renal Cell', 'Cell Line, Transformed', 'Graft Survival', 'Lung Neoplasms', 'Mice', 'Mice, Inbred C57BL', 'Neoplasm Invasiveness', 'Subrenal Capsule Assay', 'Urinary Bladder Neoplasms'] | 8,376,144 | [['B01.050'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['A11.251.210.172'], ['G12.875.545.340'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.05... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of new reference genes in papaya for accurate transcript normalization under different experimental conditions. | Real-time reverse transcription PCR (RT-qPCR) is a preferred method for rapid and accurate quantification of gene expression studies. Appropriate application of RT-qPCR requires accurate normalization though the use of reference genes. As no single reference gene is universally suitable for all experiments, thus refere... | ['Carica', 'Gene Expression Profiling', 'Gene Expression Regulation, Plant', 'Genes, Plant', 'Genetic Association Studies', 'Plant Proteins', 'RNA, Messenger', 'Reference Standards', 'Reproducibility of Results', 'Reverse Transcriptase Polymerase Chain Reaction', 'Software'] | 22,952,972 | [['B01.650.940.800.575.912.250.192.500'], ['E05.393.332'], ['G05.308.375'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['E05.393.385'], ['D12.776.765'], ['D13.444.735.544'], ['E05.978.808'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.393.620.500.725'], ['L01.224.900... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Restrictive events in the replication of hepatitis A virus in vitro. | Hepatitis A virus was purified from the feces of 2 patients with unrelated, naturally acquired infections and was inoculated into FRhK-4 cells. Analysis of protein synthesis by double-label coelectrophoresis and subtraction allowed the resolution of virus-specific proteins synthesized during infection. In FRhK-4 cells ... | ['Antigens, Surface', 'Cells, Cultured', 'Fluorescent Antibody Technique', 'Hepatovirus', 'Humans', 'Poliovirus', 'Viral Proteins', 'Virus Replication'] | 2,995,272 | [['D23.050.301'], ['A11.251'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B04.450.420', 'B04.820.578.750.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.578.750.284.184.500'], ['D12.776.964'], ['G06.920.925... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of Na+ and K+ on the thermal denaturation of Na+ and + K+-dependent ATPase. | To increase our understanding of the physical nature of the Na+ and K+ forms of the Na+ + K+-dependent ATPase, thermal-denaturation studies were conducted in different types of ionic media. Thermal-denaturation measurements were performed by measuring the regeneration of ATPase activity after slow pulse exposure to ele... | ['Animals', 'Hot Temperature', 'Potassium', 'Protein Denaturation', 'Sodium', 'Sodium-Potassium-Exchanging ATPase', 'Swine', 'Thermodynamics'] | 6,309,139 | [['B01.050'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['G01.154.651.750.500', 'G02.111.688.750.500'], ['D01.268.549.750', 'D01.268.557.650', 'D01... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Inhibition of phosphoribosylpyrophosphate synthetase by 4-methoxy-(MRPP) and 4-amino-8-(D-ribofuranosylamino) pyrimido[5,4-d]pyrimidine (ARPP). | The basis for the antitumor activities of the exocyclic amino nucleosides 4-amino-(ARPP) and 4-methoxy-8-(D-ribofuranosylamino)pyrimido[5,4-d]pyrimidine (MRPP) was investigated. The primary target of these nucleosides appeared to be 5-phospho-alpha-D-ribofuranose-1-pyrophosphate (PRPP) synthetase. MRPP-5'-monophosphate... | ['Adenosine Deaminase', 'Adenosine Kinase', 'Animals', 'Antineoplastic Agents', 'Female', 'Mice', 'NAD', 'Nucleotides', 'Phosphoribosyl Pyrophosphate', 'Phosphotransferases', 'Pyrimidine Nucleosides', 'Ribose-Phosphate Pyrophosphokinase'] | 2,479,382 | [['D08.811.277.151.486.075'], ['D08.811.913.696.620.010'], ['B01.050'], ['D27.505.954.248'], ['B01.050.150.900.649.313.992.635.505.500'], ['D03.633.100.759.646.138.694', 'D08.211.589', 'D13.695.667.138.694', 'D13.695.827.068.694'], ['D09.408.620', 'D13.695'], ['D09.894.643.650'], ['D08.811.913.696'], ['D03.383.742.680'... | ['Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dose volume analysis of radiotherapy for inoperable patients with stage I-II endometrial carcinoma. | This study aims to assess the efficacy and toxicity of definitive radiotherapy for early-stage endometrial carcinoma. The correlation between CT-based dosimetric parameters and clinical outcomes is also evaluated. Between 2002 and 2006, 10 medically inoperable patients with T1-2 endometrial carcinoma were treated with ... | ['Aged', 'Aged, 80 and over', 'Brachytherapy', 'Carcinoma, Endometrioid', 'Endometrial Neoplasms', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Middle Aged', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 21,857,147 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.815.150'], ['C04.557.470.200.025.240', 'C04.588.945.418.948.585.124', 'C13.351.500.056.630.705.331', 'C13.351.937.418.685.331', 'C13.351.937.418.875.200.124', 'C19.391.630.705.331'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Behavior of junction channels between rat glomus cells during normoxia and hypoxia. | The activity of gap junction channels between cultured and clustered carotid body glomus cells of the rat was studied with dual voltage clamping during normoxia (PO(2) 300 Torr) and hypoxia induced by sodium dithionite (Na(2)S(2)O(4)) or 100% N(2). Na(2)S(2)O(4) reduced the saline PO(2) to approximately 10 Torr, wherea... | ['Animals', 'Calcium', 'Carotid Body', 'Cell Hypoxia', 'Cells, Cultured', 'Electrophysiology', 'Gap Junctions', 'Hydrogen-Ion Concentration', 'In Vitro Techniques', 'Nitrogen', 'Patch-Clamp Techniques', 'Rats', 'Rats, Wistar', 'Sulfates'] | 12,163,517 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A08.675.650.915.500.600.150', 'A08.800.950.500.600.150', 'A11.671.650.915.500.600.150'], ['G03.197.300', 'G04.270.300'], ['A11.251'], ['H01.158.344.528', 'H01.158.782.236'], ['A11.284.149.165.420.471'], ['G02.300'], ['E05.481'], ['D01.268.604', 'D01... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of covalent adducts to protein sulfur nucleophiles by alkaline permethylation. | We recently reported on the identification of metabolites of the hepatotoxin bromobenzene covalently bound to rat liver protein sulfur nucleophiles (D. E. Slaughter and R. P. Hanzlik, Chem. Res. Toxicol. 4, 349-359 (1991). Central to that study was our development of a method called alkaline permethylation which conver... | ['Alkalies', 'Animals', 'Biochemistry', 'Bromobenzenes', 'Evaluation Studies as Topic', 'Liver', 'Methylation', 'Proteins', 'Rats', 'Sulfur'] | 8,452,222 | [['D01.045'], ['B01.050'], ['H01.158.201', 'H01.181.122'], ['D02.455.426.559.389.220', 'D02.455.526.368.150'], ['E05.337', 'N05.715.360.335'], ['A03.620'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['D12.776'], ['B01.050.150.900.649.313.992.635.505.700'], ['D01.268.185.900']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Spontaneous regression of two putative supratentorial haemangioblastomas in one patient. | Supratentorial haemangioblastomas are exceedingly rare lesions. We report a patient with spontaneous regression of two suspected supratentorial haemangioblastomas after removal of one lesion. The patient was a 61-year-old man who had a generalised seizure. Investigation with MRI revealed three supratentorial lesions si... | ['Brain Neoplasms', 'Craniotomy', 'Frontal Lobe', 'Hemangioblastoma', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neoplasm Regression, Spontaneous', 'Occipital Lobe'] | 18,026,706 | [['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E04.525.190'], ['A08.186.211.200.885.287.500.270'], ['C04.557.645.375.380.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C04.697.670', 'C23.550.727.670', 'G16.767.500'], ['A08.186.211.200.885.287.5... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Synuclein ã protects Akt and mTOR and renders tumor resistance to Hsp90 disruption. | Heat shock protein (Hsp)90 regulates many key pathways in oncogenesis, including Akt and mammalian target of rapamycin (mTOR). The strengths of disruption of Hsp90 in cancer therapy include their versatility in inhibiting a wide range of oncogenic pathways. The present study demonstrated that synuclein ã (SNCG) protect... | ['Animals', 'Benzoquinones', 'Breast Neoplasms', 'Cell Line, Tumor', 'Female', 'HSP90 Heat-Shock Proteins', 'Humans', 'Lactams, Macrocyclic', 'MCF-7 Cells', 'Mice', 'Mice, Nude', 'Molecular Dynamics Simulation', 'Neoplasm Proteins', 'Neoplasm Transplantation', 'Proto-Oncogene Proteins c-akt', 'Signal Transduction', 'Su... | 24,954,510 | [['B01.050'], ['D02.806.250'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.776.580.216.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.589.327', 'D04.345.295'], ['A11.251.210.190.630'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Western-blot with VLSE protein and "in vivo" antigens in Lyme borreliosis diagnosis]. | The aim of the study was the evaluation of the efficiency of Western blot (EcoLine) test detecting simoultanous presence of IgM and IgG antibodies against B. burgdorferi in diagnosis of early and late stage of Lyme borreliosis. The comparison of results achieved by performing test Western-blot, ELISA (based on recombin... | ['Antibodies, Bacterial', 'Antigens, Bacterial', 'Bacterial Proteins', 'Blotting, Western', 'Borrelia burgdorferi', 'Enzyme-Linked Immunosorbent Assay', 'Erythema Chronicum Migrans', 'Humans', 'Immunoglobulin G', 'Immunoglobulin M', 'Lipoproteins', 'Lyme Disease', 'Lyme Neuroborreliosis', 'Sensitivity and Specificity'] | 16,909,799 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D23.050.161'], ['D12.776.097'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['B03.440.425.410.711.193.150.125', 'B03.851.595.193.150.125'], ['E05.478.566.350.170', '... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Electrical properties of phasic and tonic muscle fibres of the abdominal flexor muscles in crayfish. | Phasic and tonic abdominal flexor muscle fibres of two anatomically different muscles in the crayfish Procambarus clarkii or Astacus sp. were investigated using electrophysiological techniques. 1. In phasic muscle, fibres were electrically coupled. They were very tightly packed and could not be isolated. No coupling wa... | ['Animals', 'Astacoidea', 'Electric Conductivity', 'Muscle Contraction', 'Muscles'] | 753,922 | [['B01.050'], ['B01.050.500.131.365.190.070'], ['G01.358.500.249.277'], ['G11.427.494'], ['A02.633', 'A10.690']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Unilateral drop finger due to cervical spondylosis at the C6/7 intervertebral level. | A 64-year-old man who presented right drop fingers without pyramidal signs due to cervical spondylosis is reported. Magnetic resonance imaging showed a high signal intensity change on T2-weighted scans of the spinal cord at the C6/7 intervertebral level. Evoked spinal cord potentials following ulnar nerve stimulation w... | ['Cervical Vertebrae', 'Fingers', 'Humans', 'Male', 'Middle Aged', 'Paralysis', 'Radiography', 'Spinal Osteophytosis'] | 12,898,322 | [['A02.835.232.834.151'], ['A01.378.800.667.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.597.622', 'C23.888.592.636'], ['E01.370.350.700'], ['C05.116.900.815']] | ['Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
NO-sartans: a new class of pharmacodynamic hybrids as cardiovascular drugs. | The aim of this work was to develop lead pharmacodynamic hybrids, NO-sartans, possessing the characteristics of a typical AT1-antagonist and of a "slow NO donor", by adding NO-donor side chains to losartan. These new compounds, 2a and 2b, displayed vasorelaxing effects, due to the release of NO, and antagonized the vas... | ['Angiotensin II Type 1 Receptor Blockers', 'Animals', 'Antihypertensive Agents', 'Blood Pressure', 'Losartan', 'Rats', 'Rats, Inbred SHR', 'Structure-Activity Relationship', 'Vasodilator Agents'] | 15,509,155 | [['D27.505.519.162.500'], ['B01.050'], ['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D02.455.426.559.389.185.475', 'D03.383.129.308.507', 'D03.383.129.617.467'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.300', 'B01.050.150.900.649.313.992.635.505.700.400.300'], ['G0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increasing adolescent immunization rates in primary care: strategies physicians use and would consider implementing. | Strategies to increase adolescent immunization rates have been suggested, but little is documented about which strategies clinicians actually use or would consider. In spring 2010, we surveyed primary care physicians from 2 practice-based research networks (PBRNs): Greater Rochester PBRN (GR-PBRN) and national pediatri... | ['Adolescent', 'Advisory Committees', 'Age Factors', 'Female', 'Follow-Up Studies', 'Health Care Surveys', 'Humans', 'Immunization', 'Incidence', 'Influenza Vaccines', 'Male', "Practice Patterns, Physicians'", 'Primary Health Care', 'Statistics, Nonparametric', 'Surveys and Questionnaires', 'United States', 'Vaccinatio... | 23,580,625 | [['M01.060.057'], ['N03.706.742.500'], ['N05.715.350.075', 'N06.850.490.250'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[The Registry of Spanish Heart Transplantation. Eleventh official report]. | As carried out since 1991, the Section of Heart Transplantation of the Spanish Cardiology Society presents an analysis of the characteristics and results of all transplants performed in Spain since the beginning of this activity (1984) up to December 31 of the year before its publication. The 336 transplants performed ... | ['Heart Transplantation', 'Humans', 'Registries', 'Spain'] | 11,171,486 | [['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.300.715.700', 'N06.850.520.308.970'], ['Z01.542.846']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Parameters altering the success of the one-anastomosis rat heart-lung transplant. | The single-anastomosis heart-lung transplantation method in the rat developed by Lee and associates has been examined and has proven to be simple and reproducible. Technical procedures are discussed emphasizing those procedures that require special caution to ensure successful graft function. The donor and recipient ra... | ['Animals', 'Graft Rejection', 'Graft Survival', 'Heart Transplantation', 'Heart-Lung Transplantation', 'Lung Transplantation', 'Male', 'Rats', 'Rats, Inbred F344', 'Rats, Inbred Lew', 'Tissue Donors', 'Transplantation Immunology'] | 3,123,870 | [['B01.050'], ['G12.875.545.328'], ['G12.875.545.340'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['E04.100.376.475.450', 'E04.928.220.390.450', 'E04.928.600.495.450', 'E04.936.450.475.450', 'E04.936.450.495.450'], ['E04.928.600.495', 'E04.936.450.495'], ['B01.050.150.900.649.313.992.635.505.700'], ['B... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effects of ingested and intravenous glucose on forearm uptake of glucose and glucogenic substrate in normal man. | The forearm uptake of glucose, lactate, and alanine was determined in overnight fasted man following both oral glucose loading and the intravenous (i.v.) infusion of glucose in an absorption pattern. Arterial glucose concentrations were lower following oral than following i.v. loading and forearm glucose uptake was 50%... | ['Administration, Oral', 'Adult', 'Blood Glucose', 'Female', 'Forearm', 'Gluconeogenesis', 'Glucose', 'Humans', 'Infusions, Parenteral', 'Lactates', 'Lactic Acid', 'Liver Glycogen', 'Male', 'Pyruvates', 'Pyruvic Acid'] | 6,642,087 | [['E02.319.267.100'], ['M01.060.116'], ['D09.947.875.359.448.500'], ['A01.378.800.585'], ['G02.111.158.500', 'G03.191.500'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.510'], ['D02.241.511.459'], ['D02.241.511.459.450'], ['D05.750.078.562.388.518', 'D09.698.365.388.518'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Nutrient digestibility of solvent-extracted Brassica napus and Brassica juncea canola meals and their air-classified fractions fed to ileal-cannulated grower pigs. | Energy and nutrient digestibility of solvent-extracted canola meal (CM) is limited in pigs by its relatively high fiber content. The seed hull, which greatly contributes to the fiber content of CM, is denser than the oil-free cotyledon. By utilizing streams of air, air classification partially separates these seed comp... | ['Air', 'Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Brassica napus', 'Diet', 'Digestion', 'Energy Metabolism', 'Food', 'Ileum', 'Mustard Plant', 'Particle Size', 'Plant Extracts', 'Solvents', 'Swine'] | 25,568,370 | [['G16.500.275.063.150', 'N06.230.300.100.150'], ['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['B01.650.940.800.575.912.250.157.200.249'], ['G07.203.650.240'], ['G07.203.650.250', 'G10.261.190'], ['G03.295'], ['G07.203.300', 'J02.500'], ['A03.556.124.684.249', 'A03.556.249.124'], ['B01.... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The effect of seasonality on the structure of rotifers in a black-water shallow lake in Central Amazonia. | Rotifers have often been used as indicators of sudden changes in physical and chemical features of the aquatic environment. Such features vary greatly during flood pulse events in small lakes connected to major floodplains. However, few are the studies that investigate the consequences of the flood pulse in rotifer spe... | ['Animals', 'Brazil', 'Fresh Water', 'Lakes', 'Population Density', 'Population Dynamics', 'Rotifera', 'Seasons'] | 25,119,730 | [['B01.050'], ['Z01.107.757.176'], ['G16.500.275.280', 'N06.230.232'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['N01.224.600', 'N06.850.505.400.600'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['B01.050.500.500.770'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525']] | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Human dietary intake and excretion of dioxin-like compounds. | Human dietary intake and excretion of polychlorinated dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and biphenyls (PCBs)--collectively referred to as dioxin-like compounds (DLCs)--were investigated. Two groups of seven subjects were studied during 1999 and 2000: one aged 23.9 +/- 4.5 years, the other aged 49.4 +/- ... | ['Adult', 'Benzofurans', 'Body Burden', 'Dibenzofurans, Polychlorinated', 'Diet', 'Environmental Exposure', 'Environmental Pollutants', 'Food Contamination', 'Humans', 'Male', 'Middle Aged', 'Polychlorinated Biphenyls', 'Polychlorinated Dibenzodioxins', 'Risk Assessment', 'Soil Pollutants'] | 12,729,259 | [['M01.060.116'], ['D03.633.100.127'], ['E05.799.638.231', 'N06.850.460.200'], ['D02.309.250', 'D03.633.300.258.500'], ['G07.203.650.240'], ['N06.850.460.350'], ['D27.888.284'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
The increase in surface CXCR4 expression on lung extravascular neutrophils and its effects on neutrophils during endotoxin-induced lung injury. | Inflammatory stimuli, such as a microbes or lipopolysaccharides, induce a rapid release of neutrophils from the bone marrow and promote neutrophil migration into inflamed sites to promote host defense. However, an excess accumulation and retention of neutrophils in inflamed tissue can cause severe tissue injuries in th... | ['Animals', 'Cell Death', 'Chemokine CXCL12', 'L-Selectin', 'Lipopolysaccharides', 'Lung', 'Lung Injury', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Neutrophils', 'Receptors, CXCR4', 'Signal Transduction', 'Sulfoglycosphingolipids'] | 21,460,863 | [['B01.050'], ['G04.146'], ['D12.644.276.374.200.120.600', 'D12.776.467.374.200.120.600', 'D23.125.300.120.600', 'D23.469.200.120.600', 'D23.529.374.200.120.600'], ['D12.776.395.550.200.625.903', 'D12.776.395.550.200.700.510', 'D12.776.503.843.510', 'D12.776.543.550.200.625.903', 'D12.776.543.550.200.700.510', 'D12.776... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genotype-dependent molecular evolution of sheep bovine spongiform encephalopathy (BSE) prions in vitro affects their zoonotic potential. | Prion diseases are rare fatal neurological conditions of humans and animals, one of which (variant Creutzfeldt-Jakob disease) is known to be a zoonotic form of the cattle disease bovine spongiform encephalopathy (BSE). What makes one animal prion disease zoonotic and others not is poorly understood, but it appears to i... | ['Animals', 'Brain', 'Cattle', 'Encephalopathy, Bovine Spongiform', 'Evolution, Molecular', 'Genotype', 'Glycosylation', 'Humans', 'Prions', 'Protein Folding', 'Protein Processing, Post-Translational', 'Scrapie', 'Sheep, Domestic', 'Zoonoses'] | 25,100,723 | [['B01.050'], ['A08.186.211'], ['B01.050.150.900.649.313.500.380.271'], ['C01.207.800.260', 'C10.228.228.800.260', 'C10.574.843.300', 'C22.196.250'], ['G05.045.250', 'G16.075.250'], ['G05.380'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.785'], ['G01.15... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Performance of daily activities by older adults with dementia: the role of an assistive robot. | Older adults with cognitive impairment often have difficulties in remembering the proper sequence of activities of daily living (ADLs) or how to use the tools necessary to perform ADLs. They, therefore, require reminders in a timely fashion while performing ADLs. This is a very stressful situation for the caregivers of... | ['Activities of Daily Living', 'Aged', 'Dementia', 'Feasibility Studies', 'Humans', 'Robotics', 'Self-Help Devices'] | 24,187,224 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['C10.228.140.380', 'F03.615.400'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
Extracellular matrix turnover and inflammatory markers independently predict functional status and outcome in chronic heart failure. | BACKGROUND: Inflammatory pathways may promote extracellular matrix (ECM) remodeling and chronic heart failure (CHF) progression. The relationship between markers of inflammation and of ECM remodeling, and their influence on functional status and outcomes has not been examined in a large cohort of CHF patients.METHODS A... | ['Aged', 'Biomarkers', 'Chronic Disease', 'Cohort Studies', 'Double-Blind Method', 'Extracellular Matrix', 'Female', 'Heart Failure', 'Humans', 'Inflammation Mediators', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Survival Rate', 'Treatment Outcome'] | 18,672,194 | [['M01.060.116.100'], ['D23.101'], ['C23.550.291.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['A11.284.295.310'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D23.469'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Rat genomic structure of amidophosphoribosyltransferase, cDNA sequence of aminoimidazole ribonucleotide carboxylase, and cell cycle-dependent expression of these two physically linked genes. | Genomic structure of rat amidophosphoribosyltransferase (ATase; EC 2.4.2.14), which catalyzes the first committed step in de novo purine nucleotide synthesis, was determined by polymerase chain reaction (PCR)-based methods. There are 11 exons and all exon-intron boundaries were conserved among rat, human, and chicken A... | ['Amidophosphoribosyltransferase', 'Amino Acid Sequence', 'Animals', 'Base Sequence', 'Carboxy-Lyases', 'Cell Cycle', 'DNA, Complementary', 'Gene Expression Regulation, Enzymologic', 'Molecular Sequence Data', 'Rats', 'Rats, Wistar', 'Sequence Alignment'] | 7,742,366 | [['D08.811.913.400.725.130'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D08.811.520.224.125'], ['G04.144'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['G05.308.320'], ['L01.453.245.667'], ['B01.050.150.900.6... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Germline p53 mutation in a Micronesian child with adrenocortical carcinoma and subsequent osteosarcoma. | In 1990, an 18-month-old Micronesian girl was initially diagnosed with a right adrenocortical carcinoma. More than a decade later (2003), she was diagnosed with metastatic osteosarcoma with the primary in her right proximal fibula. Given this child's remarkable history of malignancy, she underwent testing for a genetic... | ['Adrenal Cortex Neoplasms', 'Adrenocortical Carcinoma', 'Bone Neoplasms', 'Codon', 'Female', 'Germ-Line Mutation', 'Humans', 'Infant', 'Magnetic Resonance Imaging', 'Micronesia', 'Neoplasms, Second Primary', 'Osteosarcoma', 'Radiography', 'Tumor Suppressor Protein p53'] | 18,989,156 | [['C04.588.322.078.265', 'C19.053.098.265', 'C19.053.347.500', 'C19.344.078.265'], ['C04.557.470.200.025.152', 'C04.588.322.078.265.750', 'C19.053.098.265.750', 'C19.053.347.500.750', 'C19.344.078.265.750'], ['C04.588.149', 'C05.116.231'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['G05... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Lidocaine Concentration in Oral Tissue by the Addition of Epinephrine. | The vasoconstrictive effect due to the addition of epinephrine to local anesthetic has been clearly shown by measuring blood-flow volume or blood anesthetic concentration in oral mucosal tissue. However, there are no reports on the measurement of anesthetic concentration using samples directly taken from the jawbone an... | ['Absorption, Physiological', 'Anesthetics, Local', 'Animals', 'Arterial Pressure', 'Chromatography, High Pressure Liquid', 'Epinephrine', 'Lidocaine', 'Male', 'Maxilla', 'Mouth Mucosa', 'Rabbits', 'Time Factors', 'Tissue Distribution', 'Vasoconstrictor Agents'] | 26,866,407 | [['G03.015.500', 'G03.787.024.500', 'G07.690.725.015.500'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['B01.050'], ['G09.330.380.076.347'], ['E05.196.181.400.300'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Periodontal status of mandibular incisors after pronounced orthodontic advancement during adolescence: a follow-up evaluation. | The purpose of this study was to analyze whether pronounced orthodontic advancement of the mandibular incisors during Class II correction in the mixed dentition results in gingival recession. Through mandibular superimposition of the pretreatment and posttreatment cephalograms of 67 Class II patients who were treated w... | ['Adolescent', 'Cephalometry', 'Connective Tissue', 'Dental Models', 'Dental Plaque Index', 'Dentition, Mixed', 'Extraoral Traction Appliances', 'Female', 'Follow-Up Studies', 'Gingiva', 'Gingival Hemorrhage', 'Gingival Recession', 'Humans', 'Incisor', 'Male', 'Malocclusion, Angle Class II', 'Mandible', 'Odontometry', ... | 11,174,531 | [['M01.060.057'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['A10.165'], ['E06.261', 'J01.897.280.500.545.129.200', 'L01.178.820.090.545.129.200'], ['E05.318.308.980.438.300.300', 'E06.208.250', 'N05.715.360.300.800.438.300.325', 'N06.850.520.308.980.438.300.300', 'N06.890.160.090'], ['A14.549.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 |
Erwinia carotovora DsbA mutants: evidence for a periplasmic-stress signal transduction system affecting transcription of genes encoding secreted proteins. | The dsbA genes, which encode major periplasmic disulfide-bond-forming proteins, were isolated from Erwinia carotovora subsp. carotovora (Ecc) and Erwinia carotovora subsp. atroseptica (Eca), and the dsbC gene, encoding another periplasmic disulfide oxidoreductase was isolated from Ecc. All three genes were sequenced an... | ['Cellulase', 'Endopeptidases', 'Gene Expression Regulation, Bacterial', 'Genes, Bacterial', 'Immunoblotting', 'Molecular Sequence Data', 'Mutation', 'Pectobacterium carotovorum', 'Periplasm', 'Protein Disulfide-Isomerases', 'Sequence Analysis, DNA', 'Signal Transduction', 'Solanum tuberosum', 'Transcription, Genetic',... | 10,463,161 | [['D08.811.277.450.420.200.200'], ['D08.811.277.656.300'], ['G05.308.300'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['E05.478.566.320', 'E05.601.470.320'], ['L01.453.245.667'], ['G05.365.590'], ['B03.440.450.425.585.120', 'B03.660.250.150.542.120'], ['A11.284.295.680'], ['... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Multistrain experiments for screening toxic substances. | The advantages of using homogeneous experimental groups (inbred animal strains) and of using multiple groups within an experiment, based on the power of the Mantel-Haenszel test, were investigated. A simulation experiment was performed to empirically calculate the power of a one-sided Mantel-Haenszel test for multistra... | ['Animals', 'Research Design', 'Statistics as Topic', 'Toxicology'] | 2,709,435 | [['B01.050'], ['E05.581.500', 'H01.770.644.728'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830'], ['H01.158.891', 'H02.884']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Single amino acid substitutions in the reactive site of antithrombin leading to thrombosis. Congenital substitution of arginine 393 to cysteine in antithrombin Northwick Park and to histidine in antithrombin Glasgow. | Antithrombin Northwick Park and antithrombin Glasgow are functionally variant antithrombins with impaired abilities to interact with thrombin. Thrombosis is associated with their inheritance. Both of the purified, reduced, and S-carboxymethylated variant antithrombins were treated with cyanogen bromide and the major po... | ['Amino Acid Sequence', 'Antithrombin III', 'Arginine', 'Cyanogen Bromide', 'Cysteine', 'Genetic Variation', 'Histidine', 'Humans', 'Mass Spectrometry', 'Molecular Sequence Data', 'Peptide Fragments', 'Serine Endopeptidases', 'Thrombosis', 'Trypsin'] | 3,162,733 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.644.861.060.500', 'D12.776.124.790.106.125', 'D12.776.377.715.085.125', 'D12.776.872.060.500', 'D23.113.025'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D01.139.300.050.100', 'D01.625.175'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Assessment of the efficacy and safety of low frequency, low intensity magnetic fields in patients after knee endoprosthesis plasty. Part 2: a clinical study. | The purpose of this clinical study was to assess low frequency, low intensity magnetic fields in the enhancement of the physical rehabilitation of patients after knee endoprosthesis surgery. The study included 62 patients who underwent total knee arthroplasty. Group A consisted of 32 patients who were physically rehabi... | ['Aged', 'Female', 'Humans', 'Knee Prosthesis', 'Magnetics', 'Male', 'Middle Aged', 'Range of Motion, Articular'] | 19,089,801 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.400.410'], ['H01.671.493'], ['M01.060.116.630'], ['E01.370.600.700', 'G11.427.760']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Subsequent pregnancy outcome in patients with spontaneous resolution of HCG after evacuation of hydatidiform mole: comparison between complete and partial mole. | This study compared subsequent pregnancy outcome in patients with complete and partial hydatidiform moles. Among 1052 patients with molar pregnancy (complete mole, 801; partial mole, 251) monitored at Chiba University Hospital between 1981 and 1999, 891 patients (84.7%) had spontaneous resolution of human chorionic gon... | ['Adolescent', 'Adult', 'Chorionic Gonadotropin', 'Female', 'Humans', 'Hydatidiform Mole', 'Middle Aged', 'Pregnancy', 'Pregnancy Outcome', 'Recurrence', 'Risk Factors', 'Trophoblastic Neoplasms', 'Uterine Neoplasms'] | 11,387,305 | [['M01.060.057'], ['M01.060.116'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.955.416.812', 'C04.850.908.416.750', 'C13.703.720.949.416.875'], ['M01.060.116.630'], ['G08.686.784.769'], ['E01.789.700', 'G08.686.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Why Carba-LNA-modified oligonucleotides show considerably improved 3'-exonuclease stability compared to that of the LNA modified or the native counterparts: A Michaelis-Menten kinetic analysis. | In this study, 12 different native or LNA, carba-LNA-modified dinucleoside phosphates were designed as simple chemical models to study how carba-LNA modifications improve the 3'-exonuclease (SVPDE in this study) resistance of internucleotidic phosphate compared to those exhibited by LNA-modified and the native counterp... | ['Base Sequence', 'Dimerization', 'Dinucleoside Phosphates', 'Exodeoxyribonucleases', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Molecular Structure', 'Nucleic Acid Conformation', 'Oligonucleotides', 'Protein Binding', 'Stereoisomerism'] | 20,225,808 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.206', 'G03.230'], ['D13.695.250'], ['D08.811.277.352.335.375', 'D08.811.277.352.365.290'], ['G01.374.661', 'G02.111.490'], ['E05.196.867.519'], ['E05.599.595'], ['G02.111.570', 'G02.466'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.695.578.424'], ['G0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Molecular epidemiology of human astrovirus infections in Kolkata, India. | UNLABELLED: The study is aimed to determine the seasonal distribution and clinical characteristics of astroviruses associated with acute watery diarrhoea among children in Kolkata and characterize them at the molecular level.METHOD OF STUDY: Faecal specimens of acute watery diarrhoea cases (n=857) and non-diarrhoeic sa... | ['Adult', 'Astroviridae Infections', 'Child', 'Child, Preschool', 'Diarrhea', 'Humans', 'India', 'Infant', 'Mamastrovirus', 'Molecular Epidemiology', 'Phylogeny', 'Prevalence', 'Seasons'] | 16,546,454 | [['M01.060.116'], ['C01.925.782.105'], ['M01.060.406'], ['M01.060.406.448'], ['C23.888.821.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['M01.060.703'], ['B04.820.578.250.500'], ['E05.318.416', 'E05.393.522', 'H01.158.201.636.475.500', 'H01.158.273.343.595.475.500', 'H01.181.122.650.475.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Nosocomial Legionnaires' disease and use of medication nebulizers. | Guidelines for the prevention of nosocomial pneumonia specify that only sterile fluids should be used for aerosol therapy; however, this recommendation may not be uniformly followed. Thirteen patients with nosocomial pneumonia due to Legionella pneumophila serogroup 3 (Lp3) were identified at a community hospital in th... | ['Administration, Inhalation', 'Air Microbiology', 'Case-Control Studies', 'Cross Infection', 'Equipment Contamination', 'Humans', 'Legionella', "Legionnaires' Disease", 'Lung Diseases, Obstructive', 'Nebulizers and Vaporizers', 'Water Microbiology'] | 1,995,743 | [['E02.319.267.050'], ['H01.158.273.540.274.110', 'N06.850.425.110'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C01.248', 'C23.550.291.875.500'], ['N06.850.540'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.440.400.425.450.450', 'B03.660.250.460.460'], ['C01.150.252.400... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Removal of aldrin, dieldrin, heptachlor, and heptachlor epoxide using activated carbon and/or Pseudomonas fluorescens free cell cultures. | Degradation of aldrin (1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-1,4:5-8-dimethanonaphthalene), heptachlor (1H-1,4,5,6,7,8,8-heptachloro-3a,4,7,7a-tetrahydro-4,7-methano indene), dieldrin (1aalpha,2beta,2aalpha,3beta,6beta,6aalpha,7beta,7aalpha)-3,4,5,6,9,9-Hexachloro-1a,2,2a,3,6,6a,7,7a-octahydro-2,7:3,6-d-meth... | ['Adsorption', 'Aldrin', 'Biodegradation, Environmental', 'Charcoal', 'Chromatography, Gas', 'Dieldrin', 'Gas Chromatography-Mass Spectrometry', 'Heptachlor', 'Heptachlor Epoxide', 'Insecticides', 'Kinetics', 'Pseudomonas fluorescens', 'Soil Microbiology', 'Soil Pollutants'] | 16,785,166 | [['G01.030', 'G02.020'], ['D02.455.526.439.042'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['D01.268.150.150'], ['E05.196.181.349'], ['D02.455.526.439.371'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D02.455.526.439.516'], ['D02.455.526.439.516.350'], ['D27.720.031.700.491', 'D27.888.723.491'], ['G01.374.661... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Evaluation of patients' response to pulsed radiofrequency treatment applied to the suprascapular nerve in patients with chronic shoulder pain. | BACKGROUND AND OBJECTIVE: The aim of this study was to evaluate patient satisfaction, efficacy and safety of the pulsed radiofrequency (PRF) technique applied to the suprascapular nerve for the treatment of refractory shoulder pain.METHODS: After obtaining Institutional Research Board approval and patients' written inf... | ['Adult', 'Aged', 'Chronic Pain', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pain Measurement', 'Patient Satisfaction', 'Pulsed Radiofrequency Treatment', 'Rotator Cuff', 'Shoulder Pain', 'Treatment Outcome'] | 21,849,733 | [['M01.060.116'], ['M01.060.116.100'], ['C23.888.592.612.274'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.600.550.324'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.600'], ['E02.331.599', 'E02.779.468.599', 'E02.808.500', 'E... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis of new chiral xanthone derivatives acting as nerve conduction blockers in the rat sciatic nerve. | The synthesis and structure elucidation of three new chiral xanthone (9H-xanthon-9-one) derivatives (2-4) are fully reported. The coupling reactions of the synthesized building block 6-methoxy-9-oxo-9H-xanthene-2-carboxylic acid (1) with two enantiomerically pure amino alcohols ((S)-(+)-valinol and (S)-(+)-leucinol) an... | ['Animals', 'Chemistry Techniques, Synthetic', 'In Vitro Techniques', 'Male', 'Nerve Block', 'Neural Conduction', 'Rats', 'Rats, Wistar', 'Sciatic Nerve', 'Stereoisomerism', 'Xanthones'] | 22,819,594 | [['B01.050'], ['E05.197', 'J01.897.836.249'], ['E05.481'], ['E03.155.086.711', 'E04.525.210.550'], ['G07.265.753', 'G11.561.601'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['A08.800.800.720.450.760'], ['G02.607.445.682'], ['D03.633.300.953.852']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Overcoming drug-resistant lung cancer by paclitaxel loaded dual-functional liposomes with mitochondria targeting and pH-response. | Mitochondrion-orientated transportation of smart liposomes has been developed as a promising strategy to deliver anticancer drugs directly to tumor sites, and these have a tremendous potential for killing cancer cells, especially those with multidrug resistance (MDR). Herein we report a novel dual-functional liposome s... | ['Amino Acid Sequence', 'Animals', 'Antineoplastic Agents', 'Apoptosis', 'Caspase 9', 'Cell Line, Tumor', 'Cytochromes c', 'Drug Delivery Systems', 'Drug Resistance, Neoplasm', 'Female', 'Humans', 'Liposomes', 'Lung', 'Lung Neoplasms', 'Mice, Inbred BALB C', 'Mice, Nude', 'Mitochondria', 'Molecular Sequence Data', 'Pac... | 25,818,419 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D27.505.954.248'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126.550.900', 'D08.811.277.656.300.200.126.550.900', 'D12.644.360.024.131.155', 'D12.644.360.075.358.155', 'D12.644.360.075.405.550.900', 'D12.776.157.057.006.155', 'D12.776.476.024.139.155', 'D... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Observations of sexually transmitted disease consultations in India. | OBJECTIVES: To assess the quality of sexually transmitted disease (STD) case management provided in public and private health facilities in selected areas of Madras, Tamil Nadu, India, in order to make recommendations for improving the quality of care and promote the syndromic approach to STD treatment.METHODS: Structu... | ['Case Management', 'Female', 'HIV Infections', 'Humans', 'India', 'Interviews as Topic', 'Male', 'Patient Acceptance of Health Care', 'Patient Education as Topic', 'Program Evaluation', 'Quality of Health Care', 'Sexually Transmitted Diseases'] | 9,581,455 | [['N04.590.233.624.250'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['F01.100.150.... | ['Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
The influence of aging on poststroke depression using a rat model via middle cerebral artery occlusion. | Poststroke depression (PSD) is the most frequent psychological sequela following stroke. While previous studies describe the impact of age on brain infarct volume, brain edema, and blood-brain barrier (BBB) breakdown following ischemia, the role of age on PSD has yet to be described. Here, we examine the influence of a... | ['Age Factors', 'Aging', 'Animals', 'Avoidance Learning', 'Brain', 'Brain Edema', 'Brain Infarction', 'Brain-Derived Neurotrophic Factor', 'Depression', 'Disease Models, Animal', 'Food Preferences', 'Infarction, Middle Cerebral Artery', 'Male', 'Neurologic Examination', 'Rats', 'Rats, Sprague-Dawley', 'Sucrose', 'Sweet... | 23,761,136 | [['N05.715.350.075', 'N06.850.490.250'], ['G07.345.124'], ['B01.050'], ['F02.463.425.097', 'F02.463.785.373.173'], ['A08.186.211'], ['C10.228.140.187'], ['C10.228.140.300.150.477', 'C10.228.140.300.775.200', 'C14.907.253.092.477', 'C14.907.253.855.200', 'C23.550.513.355.250', 'C23.550.717.489.250'], ['D12.644.276.860.1... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Soc... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
The Association Between Multimorbidity and Quality of Life, Health Status and Functional Disability. | INTRODUCTION: Approximately 50% of adults have multimorbidity (MM) that is associated with greater disability, poorer quality of life (QOL) and increased psychological distress. This study assessed the association between MM and QOL, health status and functional disability in U.S. adults.METHODS: Cross-sectional study ... | ['Activities of Daily Living', 'Adult', 'Aged', 'Aged, 80 and over', 'Comorbidity', 'Cross-Sectional Studies', 'Depression', 'Female', 'Health Status', 'Humans', 'Male', 'Middle Aged', 'Quality of Life', 'United States', 'Young Adult'] | 27,432,034 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.126.350'], ['I01.240.425', 'N01.224.425', 'N06.850.50... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Enantiomeric composition of amphetamine and methamphetamine derived from the precursor compound famprofazone. | Fourteen different metabolic precursors of amphetamine or methamphetamine have previously been identified. Many of these drugs are available only by prescription and several are only available in some parts of the world and not in others. One of these drugs, famprofazone, is available over-the-counter which complicates... | ['Amphetamines', 'Anti-Inflammatory Agents, Non-Steroidal', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Male', 'Methamphetamine', 'Pyrazoles', 'Pyrazolones', 'Stereoisomerism'] | 8,682,419 | [['D02.092.471.683.152'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.471.683.152.619'], ['D03.383.129.539'], ['D03.383.129.539.850'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Nontuberculous infectious osteoarthritis in adults (excluding spondylodiscitis) in rheumatology]. | Analysis of twenty five personal observations of septic osteoarthritis compared with information from the literature led the authors to the following conclusions: 1) Diagnosis of septic osteo-arthritis must be considered when confronted with a picture of acute or subacute arthritis generally inflamed with variable feve... | ['Adolescent', 'Adult', 'Aged', 'Anti-Bacterial Agents', 'Antistreptolysin', 'Arthritis, Infectious', 'Blood', 'Blood Sedimentation', 'Body Temperature', 'Female', 'Humans', 'Immobilization', 'Injections, Intra-Articular', 'Male', 'Middle Aged', 'Neutrophils', 'Sacroiliac Joint', 'Synovial Fluid'] | 857,289 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122.085'], ['D12.776.124.486.485.114.107.288', 'D12.776.124.790.651.114.125.288', 'D12.776.377.715.548.114.125.288'], ['C01.100', 'C05.550.114.099'], ['A12.207.152', 'A15.145'], ['E01.370.225.625.125', 'E05.200.625.125'], ['E01.370.600.875.374', 'G07... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Learning Boolean queries for article quality filtering. | Prior research has shown that Support Vector Machine models have the ability to identify high quality content-specific articles in the domain of internal medicine. These models, though powerful, cannot be used in Boolean search engines nor can the content of the models be verified via human inspection. In this paper, w... | ['Algorithms', 'Artificial Intelligence', 'Decision Trees', 'Information Storage and Retrieval', 'Medical Subject Headings', 'Periodicals as Topic', 'PubMed'] | 15,360,815 | [['G17.035', 'L01.224.050'], ['G17.035.250', 'L01.224.050.375'], ['G17.162.500'], ['L01.313.500.750.280', 'L01.470'], ['L01.453.245.945.700.500'], ['L01.178.682.829.678'], ['L01.313.500.750.280.750', 'L01.313.500.750.300.188.300.650', 'L01.313.500.750.300.742.650', 'L01.470.750.500.650']] | ['Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Immortalization of different precursors of glial cells with a targeted and temperature-sensitive oncogene. | Different types of glial precursor cell lines were obtained after stable transfection of brain cells with the pJC-SVLTtsA vector carrying the tsA58 simian virus 40 large T (SVLT) gene driven by the promoter of a gliotropic strain of JC papovavirus. The immortalized cells were conditional for growth: they expressed the ... | ['Animals', 'Antigens, Viral, Tumor', 'Base Sequence', 'Brain', 'Cell Differentiation', 'Cell Line', 'Gene Expression Regulation', 'JC Virus', 'Mice', 'Mitosis', 'Molecular Sequence Data', 'Nerve Tissue Proteins', 'Neuroglia', 'Oncogenes', 'Promoter Regions, Genetic', 'Rats', 'Rats, Sprague-Dawley', 'Simian virus 40', ... | 8,082,741 | [['B01.050'], ['D23.050.285.062', 'D23.050.327.062'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A08.186.211'], ['G04.152'], ['A11.251.210'], ['G05.308'], ['B04.280.210.700.615.400', 'B04.613.204.670.615.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['G04.144.220.220.781', 'G05.113.220.781'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Two pediatric cases of nonbullous histiocytoid neutrophilic dermatitis presenting as a cutaneous manifestation of lupus erythematosus. | BACKGROUND: Nonbullous neutrophilic dermatoses are seen infrequently in association with lupus erythematosus (LE). A recently described histopathologic variant of Sweet syndrome, to our knowledge, histiocytoid Sweet syndrome (HSS) has not been described in either pediatric or adult patients with LE.OBSERVATIONS: We des... | ['Biopsy, Needle', 'Child', 'Child, Preschool', 'Dermatitis', 'Diagnosis, Differential', 'Female', 'Follow-Up Studies', 'Histiocytes', 'Humans', 'Immunohistochemistry', 'Lupus Erythematosus, Cutaneous', 'Lupus Erythematosus, Systemic', 'Neutrophils', 'Risk Assessment', 'Sweet Syndrome'] | 19,015,425 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['M01.060.406'], ['M01.060.406.448'], ['C17.800.174'], ['E01.171'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Cellular immunity in children with coeliac disease. | The experimental evidence implicating defective cell-mediated immunity in coeliac disease, a condition where symptomatology is believed to be due to immunological reaction to wheat gluten, is often inconsistent and sometimes controversial. Studies of certain parameters of cellular immunity in four groups of pediatric p... | ['Adolescent', 'Animals', 'B-Lymphocytes', 'Celiac Disease', 'Child', 'Child, Preschool', 'Food Hypersensitivity', 'Humans', 'Immunity, Cellular', 'Infant', 'Leukocyte Migration-Inhibitory Factors', 'Lymphocyte Activation', 'Milk', 'T-Lymphocytes'] | 6,749,506 | [['M01.060.057'], ['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['C06.405.469.637.250', 'C18.452.603.250'], ['M01.060.406'], ['M01.060.406.448'], ['C20.543.480.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.050.40... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Streptomyces globosus DK15 and Streptomyces ederensis ST13 as new producers of factumycin and tetrangomycin antibiotics. | Fifty seven soil-borne actinomycete strains were assessed for the antibiotic production. Two of the most active isolates, designed as Streptomyces ST-13 and DK-15 exhibited a broad range of antimicrobial activity and therefore they were selected for HPLC fractionation against the most suppressed bacteria Staphylococcus... | ['Anti-Bacterial Agents', 'Bacterial Typing Techniques', 'Benz(a)Anthracenes', 'DNA, Bacterial', 'Phylogeny', 'Pyridones', 'Soil Microbiology', 'Streptomyces'] | 29,705,162 | [['D27.505.954.122.085'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['D02.455.426.559.847.149', 'D04.615.149'], ['D13.444.308.212'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D03.383.725.791'], ['H01.158.273.540.274.555', 'N06.850.425.300'], ['B03.300.390.400.810.768', 'B03.510.024.997.775', 'B03.510.415.4... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation. | BACKGROUND: Autotaxin (ATX), a tumor cell motility-stimulating factor, regulates the blood concentrations of lysophosphatidic acid (LPA), an important and multi-functional bioactive lipid, through its lysophospholipase D activity (lysoPLD). The introduction of ATX measurements into clinical laboratory testing is urgent... | ['Antigens', 'Chronic Disease', 'Female', 'Health', 'Humans', 'Hypoalbuminemia', 'Immunoenzyme Techniques', 'Liver Diseases', 'Male', 'Multienzyme Complexes', 'Nephrosis', 'Phosphodiesterase I', 'Phospholipase D', 'Phosphoric Diester Hydrolases', 'Prostatic Neoplasms', 'Pyrophosphatases'] | 17,963,703 | [['D23.050'], ['C23.550.291.500'], ['N01.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C15.378.147.607.500'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['C06.552'], ['D05.500.562', 'D08.811.600'], ['C12.777.419.630', 'C13.351.968.419.630'], ['D08.811.277.352.640.430'], ['D08.811.277.352.640... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
L-threo-dihydroxyphenylserine (L-threo-DOPS; droxidopa) in the management of neurogenic orthostatic hypotension: a multi-national, multi-center, dose-ranging study in multiple system atrophy and pure autonomic failure. | This study was designed to determine the efficacy and tolerability of increasing doses of L-threo-dihydroxyphenylserine (L-threo-DOPS) in treating symptomatic orthostatic hypotension associated with multiple system atrophy (MSA) and pure autonomic failure (PAF). Following a one-week run-in, patients (26 MSA; 6 PAF) wit... | ['Adolescent', 'Adult', 'Aged', 'Antiparkinson Agents', 'Autonomic Nervous System Diseases', 'Blood Pressure', 'Dose-Response Relationship, Drug', 'Droxidopa', 'Female', 'Humans', 'Hypotension, Orthostatic', 'Male', 'Middle Aged', 'Multiple System Atrophy', 'Norepinephrine'] | 11,710,796 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.427.090.050'], ['C10.177'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.092.311.830.220', 'D02.455.426.559.389.657.166.175.830.220', 'D12.125.154.800.875'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Hip protectors in aged-care facilities: a randomized trial of use by individual higher-risk residents. | OBJECTIVES: To investigate the effect of use of external hip protectors on occurrence of hip fracture.DESIGN: Randomized controlled trial, with randomization at the individual level.SETTING: residential aged-care facilities in urban areas of New South Wales, Australia.PARTICIPANTS: 174 women, aged 75 years and older, w... | ['Aged', 'Aged, 80 and over', 'Australia', 'Female', 'Follow-Up Studies', 'Geriatric Assessment', 'Hip Fractures', 'Homes for the Aged', 'Humans', 'Nursing Homes', 'Patient Compliance', 'Protective Devices', 'Risk Factors'] | 11,742,776 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.639.100', 'Z01.678.100.373'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['C26.404.061.... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
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