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[Intramedullary bone endoscopy (IBE). First results of experimental intramedullary endoscopy of long bone]. | INTRODUCTION: Intramedullary preparation and endoscopy of long bone is not mentioned in literature. We present our first results of experimental intramedullary endoscopy of long bone.METHODS: Experimental tests were performed at 4 corpse bones (twice tibia, twice femur).RESULTS: Intramedullary endoscopy and preparation... | ['Bone Marrow', 'Endoscopes', 'Equipment Design', 'Femur', 'Fracture Fixation, Intramedullary', 'Humans', 'Surgical Instruments', 'Tibia'] | 12,232,746 | [['A15.382.216'], ['E07.230.220', 'E07.858.240'], ['E05.320'], ['A02.835.232.043.150'], ['E04.555.300.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.858.700'], ['A02.835.232.043.650.883']] | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human chorionic gonadotropin stimulation to assess for ovarian hyperandrogenism. | STUDY OBJECTIVE: To determine whether human chorionic gonadotropin (hCG) stimulation elicits an exaggerated 17-hydroxyprogesterone (17-OHP) response in patients with functional ovarian hyperandrogenism.METHODS: In this clinical study, healthy volunteers and hyperandrogenic patients in an outpatient General Clinical Res... | ['17-alpha-Hydroxyprogesterone', 'Adolescent', 'Adult', 'Body Mass Index', 'Case-Control Studies', 'Chorionic Gonadotropin', 'DNA Primers', 'Female', 'Gonadal Steroid Hormones', 'Humans', 'Hyperandrogenism', 'Ovarian Function Tests'] | 9,593,605 | [['D04.210.500.745.745.654.829.395.400', 'D06.472.334.851.687.750.478.400'], ['M01.060.057'], ['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D06.472.699.322.326', 'D06.472.699... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A cross-talk between TrkB and Ret tyrosine kinases receptors mediates neuroblastoma cells differentiation. | Understanding the interplay between intracellular signals initiated by multiple receptor tyrosine kinases (RTKs) to give the final cell phenotype is a major pharmacological challenge. Retinoic acid (RA)-treatment of neuroblastoma (NB) cells implicates activation of Ret and TrkB RTKs as critical step to induce cell diff... | ['Cell Differentiation', 'Cell Line', 'Humans', 'Neuroblastoma', 'Phosphorylation', 'Proto-Oncogene Proteins c-ret', 'RNA, Small Interfering', 'Receptor Cross-Talk', 'Receptor Protein-Tyrosine Kinases', 'Receptor, trkB'] | 18,286,198 | [['G04.152'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.600.590.650.550', 'C04.557.470.670.590.650.550', 'C04.557.580.625.600.590.650.550'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['D08.811.913.696.620.682.725.400.087', 'D12.776.395.550.200.188.500', 'D12.776.543.131.500', ... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Healthy Children, Strong Families 2: A randomized controlled trial of a healthy lifestyle intervention for American Indian families designed using community-based approaches. | Background/Aims Few obesity prevention trials have focused on young children and their families in the home environment, particularly in underserved communities. Healthy Children, Strong Families 2 is a randomized controlled trial of a healthy lifestyle intervention for American Indian children and their families, a gr... | ['Adult', 'Child', 'Community-Based Participatory Research', 'Diet, Healthy', 'Dietary Sugars', 'Exercise', 'Family', 'Fruit', 'Healthy Lifestyle', 'Humans', 'Indians, North American', 'Obesity', 'Sleep', 'Social Media', 'Social Networking', 'Social Support', 'Stress, Psychological', 'Vegetables'] | 28,064,525 | [['M01.060.116'], ['M01.060.406'], ['H01.770.644.193', 'N05.425.104'], ['F01.829.458.205.500', 'G07.203.650.240.629'], ['D09.301.831', 'D09.947.500', 'G07.203.300.362.831', 'J02.500.362.831'], ['G11.427.410.698.277', 'I03.350'], ['F01.829.263', 'I01.880.853.150'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['F0... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
Assessment of Hereditary Thrombophilia: Performance of Protein C (PC) Testing. | Protein C (PC) is a plasma Vitamin K-dependent pro-enzyme protein that is synthesized in the liver. Upon activation, PC regulates the coagulation process by neutralizing the procoagulant activities of factors V and VIII in the presence of the cofactor Protein S. PC is a major regulator of the coagulation process. The c... | ['Blood Coagulation', 'Blood Coagulation Tests', 'Humans', 'Partial Thromboplastin Time', 'Protein C', 'Thrombophilia'] | 28,804,825 | [['G09.188.390.150'], ['E01.370.225.625.115', 'E05.200.625.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.625.115.600', 'E05.200.625.115.600', 'G09.188.660'], ['D08.622.705', 'D12.776.124.650', 'D12.776.395.635', 'D12.776.811.243.705', 'D23.113.700'], ['C15.378.925']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
ATP-containing immunoliposomes specific for cardiac myosin. | The application of ATP-loaded liposomes has been shown effective against ischemic damage in several tissues. In this study, we have prepared ATP-containing liposomes capable of specific recognition of component (myosin) specific for ischemic myocardium. ATP-containing immunoliposomes specific towards cardiac myosin wer... | ['Adenosine Triphosphate', 'Antibodies, Monoclonal', 'Antibody Specificity', 'Excipients', 'Fluorescent Dyes', 'Heart', 'Humans', 'Liposomes', 'Myocardial Ischemia', 'Myocardium', 'Myosins', 'Polyethylene Glycols'] | 16,305,365 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.100'], ['D26.650.700.419', 'D27.720.744.770.419'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['A07.541'], ['B01.050.150.900.649.313.9... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Peroxidase associated with higher plant mitochondria. | The presence of peroxidase in mitochondria from etiolated mung bean hypocotyls and skunk cabbage spadices, suggested by carbon monoxide difference spectra and the spectral response to methyl hydroperoxide, was shown to result from contamination of the isolated mitochondria by a denser particle fraction with high peroxi... | ['Lysosomes', 'Mitochondria', 'Peroxidases', 'Plants', 'Spectrophotometry'] | 6,045,295 | [['A11.284.430.214.190.875.190.550'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['D08.811.682.732'], ['B01.650'], ['E05.196.712.726', 'E05.196.867.826']] | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protective effects of the alcohol dehydrogenase-ADH1B allele in children exposed to alcohol during pregnancy. | OBJECTIVES: To examine alcohol use for mothers with and without an ADH1B*3 allele and the moderating effects of the maternal and child ADH1B*3 allele on a broad range of infant and 7.5-year outcomes.STUDY DESIGN: Blood samples from 263 black mother/child pairs (217 mothers and 239 children) were analyzed to determine i... | ['Adult', 'African Continental Ancestry Group', 'Alcohol Dehydrogenase', 'Alcohol Drinking', 'Alcohol-Induced Disorders', 'Alleles', 'Child', 'Female', 'Gene Frequency', 'Humans', 'Male', 'Multivariate Analysis', 'Pregnancy', 'Pregnancy Outcome', 'Prenatal Exposure Delayed Effects', 'Regression Analysis'] | 16,423,594 | [['M01.060.116'], ['M01.686.508.100'], ['D08.811.682.047.820.250'], ['F01.145.317.269'], ['C25.775.100.087'], ['G05.360.340.024.340.030'], ['M01.060.406'], ['G05.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['G08.686.784.769'], ['... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of rare sugar d-allulose on heat-induced gelation of surimi prepared from marine fish. | BACKGROUND: d-Allulose (Alu), the C3-epimer of d-fructose, is a non-caloric sweetener (0.39 kcal g-1 ) with a suppressive effect on postprandial blood glucose elevation. The aim of this study was to investigate the effects of Alu used as a sweetener and gel improver instead of sucrose on heat-induced gelation of surimi... | ['Animals', 'Fish Products', 'Fish Proteins', 'Fishes', 'Fructose', 'Gels', 'Hot Temperature', 'Hydrogen-Ion Concentration', 'Sweetening Agents'] | 28,417,465 | [['B01.050'], ['G07.203.300.600.875.400', 'J02.500.600.875.400'], ['D12.776.325'], ['B01.050.150.900.493'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['D20.280.320', 'D26.255.165.320'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.71... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
CDX1 expression is reduced in colorectal carcinoma and is associated with promoter hypermethylation. | The CDX1 homeobox gene encodes a transcription factor specifically expressed in normal intestinal and colonic epithelia, and CDX1 gene expression is affected during colorectal tumour progression. In this study, real-time quantitative RT-PCR was used to investigate CDX1 expression in 26 colorectal carcinomas. Reduced ex... | ['Adult', 'Aged', 'Aged, 80 and over', 'Base Sequence', 'Colonic Neoplasms', 'Colorectal Neoplasms', 'CpG Islands', 'DNA Mutational Analysis', 'DNA, Neoplasm', 'Female', 'Gene Expression Regulation, Neoplastic', 'Homeodomain Proteins', 'Humans', 'Loss of Heterozygosity', 'Male', 'Methylation', 'Middle Aged', 'Polymorph... | 15,378,566 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Natural-killer cell ligands at the maternal-fetal interface: UL-16 binding proteins, MHC class-I chain related molecules, HLA-F and CD48. | BACKGROUND: In the early stages of human placentation, the decidua is invaded by fetal extravillous trophoblast (EVT) cells. Interactions between EVT cells and local decidual leukocytes are likely to contribute to immunological accommodation of the semi-allogeneic fetus.METHODS AND RESULTS: Natural-killer group 2 membe... | ['Antigens, CD', 'CD48 Antigen', 'CD56 Antigen', 'Female', 'Fetus', 'GPI-Linked Proteins', 'HLA Antigens', 'Histocompatibility Antigens Class I', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Killer Cells, Natural', 'Leukocytes', 'Ligands', 'Membrane Proteins', 'NK Cell Lectin-Like Receptor Subfamily K', ... | 18,658,158 | [['D23.050.301.264.035', 'D23.101.100.110'], ['D12.776.395.550.448.180', 'D12.776.395.550.736.250', 'D12.776.543.484.500.180', 'D12.776.543.550.418.180', 'D12.776.543.550.746.250', 'D12.776.543.750.705.970.250'], ['D12.776.395.550.200.250.520.156', 'D12.776.543.550.200.250.520.156', 'D23.050.301.264.894.156', 'D23.050.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A systematic review of pharmacist-led medicines review services in New Zealand - is there equity for M?ori older adults? | BACKGROUND: Pharmacist involvement in medicines reviews for older adults can improve prescribing and reduce adverse drug reactions. M?ori experience poorer health outcomes than non-M?ori resulting, in part, from inequitable access to and quality of medicine-related care. Despite international data showing benefit, it i... | ['Adult', 'Drug-Related Side Effects and Adverse Reactions', 'Health Equity', 'Humans', 'Inappropriate Prescribing', 'Indigenous Peoples', 'Medication Reconciliation', 'New Zealand', 'Observational Studies as Topic', 'Pharmaceutical Services', 'Pharmacists', 'Professional Role'] | 30,733,137 | [['M01.060.116'], ['C25.100'], ['N04.590.374.350.500', 'N05.300.430.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.490', 'N02.421.450.500.249'], ['M01.686.754.254'], ['E02.319.529.500', 'N02.421.450.500.500', 'N04.452.528.460', 'N04.590.656'], ['Z01.639.760.747', 'Z01.678.100.747'], ['E05.318.372.250... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Granulomatous laryngitis of unknown etiology. | A 21-year-old man was admitted for odynophagia and hoarseness of four months duration. He smoked one and a half packs of cigarettes a day and occasionally inhaled marijuana. Indirect laryngoscopy revealed a massive swelling of the entire epiglottis, aryepiglottic folds, and arytenoids. The histopathologic diagnosis of ... | ['Adult', 'Biopsy', 'Granuloma', 'Humans', 'Laryngectomy', 'Laryngitis', 'Male', 'Sarcoidosis'] | 7,392,756 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C15.604.515.292', 'C23.550.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.580.369'], ['C01.748.368', 'C08.360.535', 'C08.730.368', 'C09.400.53... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Double-contrast with insufflated barium-meal technic in the routine radiological study of the esophagus]. | The results are reported of the esophagus double contrast examination with "Insufflated Barium Meal" technique as first part of the routine upper digestive system radiological examination. This technique gives good double contrast without those artifacts using effervescent powders and without modifying the normal radio... | ['Air', 'Barium Sulfate', 'Esophageal Diseases', 'Esophageal Neoplasms', 'Esophagitis, Peptic', 'Esophagus', 'Humans', 'Methods', 'Radiography', 'Ulcer'] | 4,095,293 | [['G16.500.275.063.150', 'N06.230.300.100.150'], ['D01.103.075', 'D01.875.800.800.850.075'], ['C06.405.117'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['C06.405.117.620.420', 'C06.405.205.663.420', 'C06.405.469.275.800.523', 'C06.405.748.586.524'], ['A03.556.8... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Evidence that Galpha(q)-coupled receptor-induced interleukin-6 mRNA in vascular smooth muscle cells involves the nuclear factor of activated T cells. | The immunosuppressant cyclosporin A inhibits transcription mediated by the nuclear factor of activated T-cells (NFAT), a key regulator of cytokine gene expression in lymphocytes that integrates phospholipase C signaling. NFAT is also expressed in vascular smooth muscle cells, but the genes it regulates there are unknow... | ['Animals', 'Cells, Cultured', 'Cyclosporine', 'DNA-Binding Proteins', 'GTP-Binding Protein alpha Subunits, Gq-G11', 'Gene Expression Regulation', 'Heterotrimeric GTP-Binding Proteins', 'Interleukin-1', 'Interleukin-6', 'Lymphocyte Activation', 'Muscle, Smooth, Vascular', 'NF-kappa B', 'NFATC Transcription Factors', 'N... | 11,040,041 | [['B01.050'], ['A11.251'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['D12.776.260'], ['D08.811.277.040.330.300.200.100.300', 'D12.644.360.360.100.300', 'D12.776.157.325.332.100.300', 'D12.776.476.375.100.300', 'D12.776.543.325.100.300'], ['G05.308'], ['D08.811.277.040.330.300.200', 'D12.644.360.360', 'D12.776.15... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A young patient with multiple arterial occlusions]. | BACKGROUND: Mild hyperhomocysteinemia due to genetic causes and nutrition factors is well known as an independent strong risk factor for premature arterial occlusive disease.CASE REPORT: A 27-year-old female with a history of two episodes of small bowel ileus due to vascular causes presented with subacute pain in the l... | ['Adult', 'Amino Acid Metabolism, Inborn Errors', 'Arterial Occlusive Diseases', 'Contraceptives, Oral, Combined', 'Female', 'Homocysteine', 'Humans', 'Ileum', 'Ischemia', 'Leg', 'Mesenteric Artery, Superior', 'Mesenteric Vascular Occlusion', 'Risk Factors', 'Smoking'] | 9,630,816 | [['M01.060.116'], ['C16.320.565.100', 'C18.452.648.100'], ['C14.907.137'], ['D26.310.360', 'D27.505.696.875.360.276.210.100', 'D27.505.954.705.360.276.210.100'], ['D02.886.030.498', 'D12.125.166.498'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684.249', 'A03.556.249.124'], ['C23.550.513'], ['A01.37... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Serum prolactin and response to treatment among cocaine-dependent individuals. | Considerable evidence indicates that dopaminergic mechanisms may modulate the central effects of cocaine. We investigated whether basal serum prolactin, a measure of central dopamine activity, differed between cocaine-dependent subjects and controls, and whether prolactin levels among cocaine patients were related to t... | ['Adult', 'African Americans', 'Ambulatory Care', 'Cocaine', 'Cocaine-Related Disorders', 'Female', 'Humans', 'Male', 'Patient Dropouts', 'Personality Inventory', 'Prognosis', 'Prolactin', 'Receptors, Dopamine', 'Reference Values', 'Substance Withdrawal Syndrome'] | 11,900,622 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['E02.760.106', 'N02.421.585.106'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['C25.775.300', 'F03.900.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.750.500.610', 'F01.145.488.887.500.61... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Measuring elderly people's quality of life through the Beck Hopelessness Scale: a study with a Spanish sample. | OBJECTIVES: Hopelessness is a key element of suicidal intent. It can instill a pessimistic outlook on the future, leading an individual to believe that suicide is the only answer to their problems. Hopelessness operates as a modulating variable between depression and suicidal behavior. The aim of this study was to conf... | ['Aged', 'Aging', 'Depression', 'Early Diagnosis', 'Factor Analysis, Statistical', 'Female', 'Frustration', 'Humans', 'Male', 'Middle Aged', 'Motivation', 'Psychiatric Status Rating Scales', 'Psychometrics', 'Quality of Life', 'Reproducibility of Results', 'Spain', 'Suicidal Ideation', 'Suicide'] | 27,786,537 | [['M01.060.116.100'], ['G07.345.124'], ['F01.145.126.350'], ['E01.390'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['F01.470.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.658', 'F01.752.543.500.750'], ['F04.711.513.653'], ['F04.711.780'], ['I01.800', 'K01.75... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Effects of soybean isoflavones on expression levels of osteoprotegerin and osteoprotegerin ligand mRNAs in bone tissues of ovariectomized rats]. | OBJECTIVE: To investigate the effects of soybean isoflavones (SI) on expression levels of osteoprotegerin (OPG) and osteoprotegerin ligand (OPGL) mRNAs in bone tissues of ovariectomized rats, and to discuss the mechanism of soybean isoflavaones in preventing and treating postmenopausal osteoporosis (PMO).METHODS: Thirt... | ['Animals', 'Bone Density', 'Bone and Bones', 'Carrier Proteins', 'Female', 'Glycoproteins', 'Isoflavones', 'Membrane Glycoproteins', 'Osteoprotegerin', 'Ovariectomy', 'RANK Ligand', 'RNA, Messenger', 'Random Allocation', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Cytoplasmic and Nuclear', 'Receptors, Tumor Necrosis F... | 16,696,921 | [['B01.050'], ['G11.427.100'], ['A02.835.232', 'A10.165.265'], ['D12.776.157'], ['D09.400.430', 'D12.776.395'], ['D03.383.663.283.266.450.400', 'D03.633.100.150.266.450.400'], ['D12.776.395.550', 'D12.776.543.550'], ['D12.776.543.750.705.852.760.949.249'], ['E04.270.282.685', 'E04.950.165.685', 'E04.950.300.680'], ['D1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Journal Club: Twitter as a source of vaccination information: content drivers and what they're saying. | This Journal Club reviews a study on the use of Twitter as a source of health-related information. | ['Blogging', 'Humans', 'Information Dissemination', 'Social Media', 'Vaccination'] | 23,726,549 | [['L01.143.140', 'L01.178.148', 'L01.559.423.906.296'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.143.443'], ['L01.178.751', 'L01.224.230.110.500.750'], ['E02.095.465.425.400.530.890', 'E05.478.550.600.890', 'N02.421.726.758.310.890', 'N06.850.780.200.425.900', 'N06.850.780.680.310.890']] | ['Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Techno-economic evaluation of producing ethanol from softwood: comparison of SSF and SHF and identification of bottlenecks. | The aim of the study was to evaluate, from a technical and economic standpoint, the enzymatic processes involved in the production of fuel ethanol from softwood. Two base case configurations, one based on simultaneous saccharification and fermentation (SSF) and one based on separate hydrolysis and fermentation (SHF), w... | ['Bioreactors', 'Computer Simulation', 'Conservation of Natural Resources', 'Cost-Benefit Analysis', 'Ethanol', 'Models, Biological', 'Models, Economic', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Technology Assessment, Biomedical', 'Wood', 'Yeasts'] | 12,892,470 | [['E07.115', 'J01.897.120.115'], ['L01.224.160'], ['J01.256', 'N06.230.080'], ['N03.219.151.125'], ['D02.033.375'], ['E05.599.395'], ['E05.318.740.500.600', 'E05.599.835.890', 'N05.715.360.750.530.500', 'N06.850.520.830.500.600'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
High-resolution computed tomography in pituitary microadenoma: is seeing believing? | Controversy surrounds the reliability of high-resolution computed tomography (CT) in the identification of functioning microadenomas, especially in patients with hyperprolactinaemia and hypercortisolaemia. We studied 34 such patients: each underwent a high-resolution CT examination of the pituitary gland and each had a... | ['Adenoma', 'Cushing Syndrome', 'Female', 'Humans', 'Male', 'Pituitary Neoplasms', 'Prolactin', 'Tomography, X-Ray Computed'] | 3,709,045 | [['C04.557.470.035'], ['C19.053.800.367'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.322.609', 'C04.588.614.250.195.885.500.600', 'C10.228.140.211.885.500.600', 'C10.228.140.617.477.600', 'C10.228.140.617.738.675', 'C10.551.240.250.700.500.500', 'C19.344.609', 'C19.700.734'], ['D06.472.699.322.576.773'... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Frequency and correlates of diary-measured hangoverlike experiences in a college sample. | A sample of college students, oversampled for smoking (N = 127, 43% smokers), monitored their daily experiences using electronic diaries over 14 days. We examined the frequency and correlates of liberally defined hangoverlike experiences (HLEs) using data from 1,595 person-days (1,325 after abstention from drinking and... | ['Adolescent', 'Adult', 'Alcohol Drinking', 'Female', 'Headache', 'Humans', 'Incidence', 'Male', 'Milk, Human', 'Prevalence', 'Students', 'Universities', 'Young Adult'] | 20,307,125 | [['M01.060.057'], ['M01.060.116'], ['F01.145.317.269'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['A12.200.467', 'A12.790.500', 'G07.203.100.700.500', 'G07.203.300.350.525.5... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phe... | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Rare case of Alstrom syndrome without obesity and with short stature, diagnosed in adulthood. | Alstrom syndrome is a rare autosomal recessive disorder characterized by retinal degeneration, sensorineural hearing loss, obesity, type 2 diabetes mellitus and chronic nephropathy. It may be associated with acanthosis nigricans, hypergonadotropic hypogonadism, hepatic dysfunction, hepatic steatosis, hyperlipidaemia, d... | ['Adult', 'Blood Glucose', 'Body Height', 'Creatinine', 'Diabetes Mellitus', 'Diagnosis, Differential', 'Fatty Liver', 'Growth Disorders', 'Humans', 'Hypogonadism', 'Kidney Diseases', 'Male', 'Retinitis Pigmentosa', 'Syndrome', 'Ultrasonography'] | 16,669,965 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['D03.383.129.308.207'], ['C18.452.394.750', 'C19.246'], ['E01.171'], ['C06.552.241'], ['C23.550.393'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.391.482'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Psychiatric emergencies: the check effect revisited. | Federal income support to persons with alcohol and drug related disabilities was ended in 1997. The argument for ending the programs was that recipients were using their benefits to purchase drugs and alcohol. This supposedly led to the "check effect," an increase in psychiatric emergencies in American communities in t... | ['Emergencies', 'Female', 'Holidays', 'Humans', 'Income', 'Male', 'Mental Disorders', 'Models, Statistical', 'Periodicity', 'San Francisco', 'Social Security', 'Substance-Related Disorders', 'Weather'] | 10,331,323 | [['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['I03.450.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.417'], ['F03'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['G01.910.645', 'G07.180.562'], ['Z01.107.567.875.580.200.700', 'Z01.107.567.875.760.200.7... | ['Diseases [C]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Effect of ICD Therapies on Mortality in the OMNI Trial. | BACKGROUND: Analyses from primary prevention trials on implantable cardioverter defibrillator (ICD) therapy have shown an association between shocks and increased mortality. Recent data suggest a similar association with antitachycardia pacing (ATP).OBJECTIVE: The OMNI study is an observational study of pacemaker and I... | ['Aged', 'Cardiac Pacing, Artificial', 'Defibrillators, Implantable', 'Electric Countershock', 'Electrophysiologic Techniques, Cardiac', 'Female', 'Humans', 'Male', 'Middle Aged', 'Product Surveillance, Postmarketing', 'Prosthesis Failure', 'Risk Factors', 'Tachycardia, Ventricular', 'Time Factors', 'Treatment Outcome'... | 26,501,695 | [['M01.060.116.100'], ['E02.331.200'], ['E07.305.250.159.175', 'E07.305.250.319.175', 'E07.695.202.175'], ['E02.331.350'], ['E01.370.370.380.245', 'E01.370.405.267'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.337.800'], ['C23.550.767.865', 'E05.325.771'], ['E05.318.740.600.800.725', 'N... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Autologous bone marrow mononuclear cell transplantation in ischemic heart failure: a prospective, controlled, randomized, double-blind study of cell transplantation combined with coronary bypass. | BACKGROUND: Bone marrow mononuclear cell (BMMC) transplantation for heart failure has shown inconsistent therapeutic efficacy.METHODS: We enrolled 104 ischemic heart failure patients scheduled for coronary artery bypass surgery (CABG). After 4- to 12-week pharmacotherapy optimization, 39 patients with left ventricular ... | ['Aged', 'Bone Marrow Transplantation', 'Combined Modality Therapy', 'Coronary Artery Bypass', 'Double-Blind Method', 'Female', 'Follow-Up Studies', 'Heart Failure', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Monocytes', 'Myocardial Infarction', 'Positron-Emission Tomography', 'Prospective Studies'... | 24,656,645 | [['M01.060.116.100'], ['E02.095.147.725.040', 'E04.936.580.040'], ['E02.186'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development. | We have isolated cDNAs for three members of a family of seven-pass transmembrane cadherins in mouse (Celsr1, 2 and 3). These three genes represent vertebrate homologues of flamingo/starry night, recently identified as an essential component of the Drosophila planar cell polarity pathway and for the correct formation of... | ['Animals', 'Cadherins', 'Drosophila', 'Drosophila Proteins', 'Embryonic and Fetal Development', 'Fetal Proteins', 'Gene Expression', 'Gene Expression Profiling', 'Humans', 'Mice', 'Receptors, Cell Surface', 'Receptors, G-Protein-Coupled'] | 11,677,057 | [['B01.050'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['G07.345.500.325', 'G08.686.784.170'], ['D12.776.320'], ['G05.297'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sequencing the nuclear genome of the extinct woolly mammoth. | In 1994, two independent groups extracted DNA from several Pleistocene epoch mammoths and noted differences among individual specimens. Subsequently, DNA sequences have been published for a number of extinct species. However, such ancient DNA is often fragmented and damaged, and studies to date have typically focused o... | ['Africa', 'Animals', 'Cell Nucleus', 'Conserved Sequence', 'Elephants', 'Evolution, Molecular', 'Extinction, Biological', 'Female', 'Fossils', 'Genome', 'Genomics', 'Hair', 'Humans', 'India', 'Male', 'Phylogeny', 'Sequence Analysis, DNA'] | 19,020,620 | [['Z01.058'], ['B01.050'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G02.111.570.580'], ['B01.050.150.900.649.833.249'], ['G05.045.250', 'G16.075.250'], ['G16.510'], ['I01.076.368.584.311'], ['G05.360.340'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['A17.360'], ['B01.050.150.900.649.313.988.400.112.4... | ['Geographicals [Z]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 |
An evaluation of diaphragmatic movement by M-mode sonography as a predictor of pulmonary dysfunction after upper abdominal surgery. | BACKGROUND: Diaphragmatic dysfunction is a major factor in the etiology of postoperative pulmonary complications after upper abdominal surgery. M-mode ultrasonography is now an accepted qualitative method of assessing diaphragmatic motion in normal and pathological conditions. In this study, we evaluated whether diaphr... | ['Abdomen', 'Adolescent', 'Adult', 'Aged', 'Analgesia, Patient-Controlled', 'Anesthesia, General', 'Diaphragm', 'Digestive System Surgical Procedures', 'Echocardiography', 'Female', 'Humans', 'Liver', 'Lung Diseases', 'Male', 'Middle Aged', 'Pain Measurement', 'Pain, Postoperative', 'Postoperative Complications', 'Pred... | 20,418,298 | [['A01.923.047'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E03.091.120'], ['E03.155.197'], ['A02.633.567.900.300'], ['E04.210'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['C08.381'], ['M01.060.116.630'], ['E01.37... | ['Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chronic obstructive pulmonary disease and cardiovascular mortality in elderly subjects from general population. | AIMS: To ascertain whether chronic obstructive pulmonary disease (COPD) is an independent risk factor for cardiovascular (CV) mortality in the elderly subjects from general population.METHODS: 3282 subjects of the Northern Italy aged > or =65 years were followed up for 12 years in the frame of the CArdiovascular STtudy... | ['Aged', 'Antihypertensive Agents', 'Cardiovascular Diseases', 'Female', 'Humans', 'Hypertension', 'Male', 'Prognosis', 'Pulmonary Disease, Chronic Obstructive', 'Risk Factors'] | 20,001,393 | [['M01.060.116.100'], ['D27.505.954.411.162'], ['C14'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E01.789'], ['C08.381.495.389'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mechanism of the Pechmann reaction: a theoretical study. | One of the most widespread synthetic routes to coumarins is the condensation of esters and phenols via the Pechmann reaction. Despite the industrial and technological importance of the reaction, its mechanism is still poorly understood. We have explored several possible reaction paths by DFT calculations at the M05-2X/... | ['Catalysis', 'Coumarins', 'Models, Molecular', 'Models, Theoretical', 'Quantum Theory', 'Solvents', 'Thermodynamics', 'Water'] | 21,932,799 | [['G02.130'], ['D03.383.663.283.446', 'D03.633.100.150.446'], ['E05.599.595'], ['E05.599'], ['H01.671.579.800'], ['D27.720.844'], ['G01.906'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
New insights into acute annular outer retinopathy. | PURPOSE: Acute annular outer retinopathy is a rare entity. There are only a few cases in the world's literature. Our study is the first to describe the spectral domain optical coherence tomography (OCT) findings in the acute presentation of this disease and to follow the disease in convalescence.METHODS: This article i... | ['Acute Disease', 'Adult', 'Female', 'Fluorescein Angiography', 'Humans', 'Retinal Diseases', 'Retrospective Studies', 'Tomography, Optical Coherence'] | 25,383,859 | [['C23.550.291.125'], ['M01.060.116'], ['E01.370.370.050.350', 'E01.370.380.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.768'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.82... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Diabetes mellitus and optic atrophy in two siblings: a report on a new association and a review of the literature. | Two siblings with diabetes mellitus and optic atrophy (Wolfram syndrome) are described. As often noted, they also had atonic urinary bladders. Only one of the siblings had some impairment of hearing. Other findings not previously reported that appeared in each subject were esophageal dysphagia and vertigo. An autopsy i... | ['Adult', 'Brain Stem', 'Deglutition Disorders', 'Diabetes Mellitus', 'Female', 'Hearing Disorders', 'Humans', 'Male', 'Optic Atrophy', 'Optic Nerve', 'Syndrome', 'Urinary Bladder Diseases', 'Vertigo'] | 6,839,924 | [['M01.060.116'], ['A08.186.211.132'], ['C06.405.117.119', 'C09.775.174'], ['C18.452.394.750', 'C19.246'], ['C09.218.458', 'C10.597.751.418', 'C23.888.592.763.393'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.292.700.225', 'C11.640.451'], ['A08.800.800.120.680'], ['C23.550.288.500'], ['C12.777.829', 'C13.35... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Frequency of methicillin resistance varies with conditions, in a population of staphylococci from a hospital environment]. | The incidence of methicillin-resistant Strains is increasing in these last years. This increase is particularly evident in Strains isolated from hospital environments. In this work we evaluated the methicillin-resistance of 58 Staphylococcus Strains, isolated from a surgical intensive care ward, in various experimental... | ['Bacteriological Techniques', 'Culture Media', 'Dose-Response Relationship, Drug', 'Humans', 'Intensive Care Units', 'Methicillin', 'Penicillin Resistance', 'Staphylococcus'] | 3,915,741 | [['E01.370.225.875.150', 'E05.200.875.150'], ['D27.720.470.305', 'E07.206'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['D02.065.589.099.750.500', 'D02.886.108.750.500', 'D03.633.100.300.750.500'], ['G06.099.225.500.600', 'G06.225.347.500.600', 'G07.69... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cortical tethering of mitochondria by the anchor protein Mcp5 enables uniparental inheritance. | During sexual reproduction in eukaryotes, processes such as active degradation and dilution of paternal mitochondria ensure maternal mitochondrial inheritance. In the isogamous organism fission yeast, we employed high-resolution fluorescence microscopy to visualize mitochondrial inheritance during meiosis by differenti... | ['Carrier Proteins', 'Mitochondria', 'Schizosaccharomyces', 'Schizosaccharomyces pombe Proteins'] | 31,582,398 | [['D12.776.157'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['B01.300.107.797', 'B01.300.930.720'], ['D12.776.354.875']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of the major physiologic phosphorylation site of human keratin 18: potential kinases and a role in filament reorganization. | There is ample in vitro evidence that phosphorylation of intermediate filaments, including keratins, plays an important role in filament reorganization. In order to gain a better understanding of the function of intermediate filament phosphorylation, we sought to identify the major phosphorylation site of human keratin... | ['Amino Acid Sequence', 'Animals', 'Baculoviridae', 'Cell Line', 'Ethers, Cyclic', 'Humans', 'Intermediate Filaments', 'Keratins', 'Mice', 'Molecular Sequence Data', 'Mutation', 'Okadaic Acid', 'Peptide Mapping', 'Phosphopeptides', 'Phosphoprotein Phosphatases', 'Phosphorylation', 'Protein-Serine-Threonine Kinases', 'S... | 7,523,419 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['B04.280.065', 'B04.525.100'], ['A11.251.210'], ['D02.355.291', 'D04.345.241'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.214.190.750.410'], ['D05.750.078.593.450', 'D12.776.220.475.450', 'D12.776.860.607'], ['B01.050.150.900.649.313.992.63... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Induced human gestational hypoprolactinemia: lack of action on fetal adrenal androgen synthesis. | To investigate the possible role of PRL in the control of fetal adrenal function, blood samples were collected from maternal peripheral and cord blood from six women at delivery, who had received treatment with bromocriptine (3.75--35 mg daily) for the entire gestation. A group of eight untreated parturients served as ... | ['Adrenal Glands', 'Adult', 'Bromocriptine', 'Dehydroepiandrosterone', 'Female', 'Fetal Blood', 'Humans', 'Maternal-Fetal Exchange', 'Pregnancy', 'Prolactin'] | 6,448,263 | [['A06.300.071'], ['M01.060.116'], ['D03.132.327.412.100', 'D03.633.400.439.131', 'D03.633.400.562.100'], ['D04.210.500.054.079.429.625', 'D04.210.500.578.502.400', 'D06.472.040.502.400', 'D06.472.334.851.968.952'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G0... | ['Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Forage-based dairying in a water-limited future: use of models to investigate farming system adaptation in southern Australia. | The irrigated dairy industry in southern Australia has experienced significant restrictions in irrigation water allocations since 2005, consistent with climate change impact predictions for the region. Simulation models of pasture growth (DairyMod), crop yield (Agricultural Production Systems Simulator, APSIM), and dai... | ['Animal Feed', 'Animals', 'Australia', 'Cattle', 'Climate Change', 'Dairying', 'Rain', 'Seasons', 'Water Supply'] | 22,720,972 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['Z01.639.100', 'Z01.678.100.373'], ['B01.050.150.900.649.313.500.380.271'], ['G16.500.175.374'], ['J01.040.246'], ['G16.500.175.859', 'G16.500.275.063.725.395', 'G16.500.750.775.450', 'N06.230.300.100.725.450', 'N06.230.520'], ['G01.910.645.661', 'G16.500.275.0... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
High-resolution 1H-NMR spectroscopy of free and glycosidically linked O-acetylated sialic acids. | A number of naturally occurring and synthetic, partially O-acetylated derivatives of N-acetylneuraminic and N-glycoloylneuraminic acids have been investigated by 360-MHz 1H-NMR spectroscopy. O-Acetylation causes strong downfield shifts for the resonances of neighbouring sugar-skeleton protons. The chemical shifts of th... | ['Acetylation', 'Glycosides', 'Magnetic Resonance Spectroscopy', 'Oligosaccharides', 'Sialic Acids'] | 7,060,578 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['D09.408'], ['E05.196.867.519'], ['D09.698.629'], ['D02.241.081.844.562.668', 'D02.241.511.902.562.668', 'D09.067.687.668', 'D09.811.589.668']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Religion and fertility in the Outer Hebrides. | Estimates of fertility in Protestant Barra and Catholic Harris, islands in the Outer Hebrides, over the period 1856-1985, show that in both islands fertility declined, although marital fertility was generally greater than in Scotland as a whole, and illegitimate fertility was less. However, in Barra during 1966-75 ther... | ['Adolescent', 'Adult', 'Birth Rate', 'Catholicism', 'Child, Preschool', 'Christianity', 'Family Characteristics', 'Female', 'Hebrides', 'Humans', 'Illegitimacy', 'Infant', 'Infant, Newborn', 'Male', 'Middle Aged', 'Pregnancy', 'Religion and Sex'] | 7,876,298 | [['M01.060.057'], ['M01.060.116'], ['E05.318.308.985.775.500', 'N01.224.935.849.500', 'N06.850.505.400.975.775.500', 'N06.850.520.308.985.775.500'], ['K01.844.188.250'], ['M01.060.406.448'], ['K01.844.188'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Humanities [K]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Attitudes of donors and recipients to gamete donation. | An anonymous questionnaire was circulated at two gamete donation clinics to survey the attitudes of donor insemination patients (n = 71; 89% response rate), sperm donors (n = 52; 85% response rate) and ovum donors (n = 5; 63% response rate) to the release of medical records with non-identifying information, or with ide... | ['Attitude', 'Disclosure', 'Female', 'Gamete Intrafallopian Transfer', 'Government Regulation', 'Humans', 'Insemination, Artificial', 'Male', 'Oocyte Donation', 'Ovum', 'Spermatozoa', 'Surveys and Questionnaires'] | 2,056,030 | [['F01.100'], ['F01.829.401.046', 'I01.880.604.583.080.134', 'L01.143.335'], ['E02.875.800.875', 'E05.820.800.875'], ['I01.880.604.394', 'N03.706.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.875.800.937', 'E05.820.800.937', 'G08.686.784.363.492'], ['E02.875.800.968', 'E05.820.800.968'], ['A05.360.490.6... | ['Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
Optimization of Phase-Change Contrast Agents for Targeting MDA-MB-231 Breast Cancer Cells. | Breast cancer remains a leading cause of death for women throughout the world. Recent advances in medical imaging technologies and tumor targeting agents signify vast potential for progress toward improved management of this global problem. Phase-change contrast agents (PCCAs) are dynamic imaging agents with practical ... | ['Breast Neoplasms', 'Cells, Cultured', 'Contrast Media', 'Female', 'Humans', 'Image Enhancement', 'Microbubbles', 'Ultrasonography'] | 30,228,045 | [['C04.588.180', 'C17.800.090.500'], ['A11.251'], ['D27.505.259.500', 'D27.720.259'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E07.553'], ['E01.370.350.850']] | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Regional chemotherapy of liver metastases in colorectal carcinoma. Intra-arterial vs intravenous plus intra-arterial therapy]. | Regional chemotherapy with floxuridine was undertaken in 50 patients (32 men and 18 women, mean age 57 years) with colorectal carcinoma with metastases only to the liver. In 25 patients (group I) the drug (0.2 mg/kg) was administered exclusively intraarterially into the hepatic artery, while in the remaining 25 (group ... | ['Adult', 'Aged', 'Colorectal Neoplasms', 'Combined Modality Therapy', 'Evaluation Studies as Topic', 'Female', 'Floxuridine', 'Fluorouracil', 'Humans', 'Infusions, Intra-Arterial', 'Infusions, Intravenous', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Mitomycins', 'Postoperative Care'] | 2,529,112 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['E02.186'], ['E05.337', 'N05.715.360.335'], ['D03.383.742.680.852.300.350', 'D13.570.230.430.432', 'D13.570.685.852.300.350'], ['D03.383... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
On the evolution of the tRNA-dependent amidotransferases, GatCAB and GatDE. | Glutaminyl-tRNA synthetase and asparaginyl-tRNA synthetase evolved from glutamyl-tRNA synthetase and aspartyl-tRNA synthetase, respectively, after the split in the last universal communal ancestor (LUCA). Glutaminyl-tRNA(Gln) and asparaginyl-tRNA(Asn) were likely formed in LUCA by amidation of the mischarged species, g... | ['Amino Acyl-tRNA Synthetases', 'Archaeal Proteins', 'Aspartate-tRNA Ligase', 'Bacterial Proteins', 'Evolution, Molecular', 'Glutamate-tRNA Ligase', 'Nitrogenous Group Transferases', 'Phylogeny', 'Protein Subunits', 'RNA, Transfer, Amino Acyl'] | 18,279,892 | [['D08.811.464.263.200'], ['D12.776.090'], ['D08.811.464.263.200.150'], ['D12.776.097'], ['G05.045.250', 'G16.075.250'], ['D08.811.464.263.200.250'], ['D08.811.913.477'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D12.776.813'], ['D12.125.780', 'D13.444.735.757.715']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Use of rhodamine 123 to examine the functional activity of P-glycoprotein in primary cultured brain microvessel endothelial cell monolayers. | The fluorescent dye, rhodamine 123, was used to evaluate the functional activity of the P-glycoprotein (P-gp) efflux transport system in primary cultured bovine brain microvessel endothelial cell (BBMEC) monolayers. Rhodamine 123 accumulation was increased significantly in BBMEC monolayers treated with the P-gp modifyi... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Animals', 'Blood-Brain Barrier', 'Brain', 'Cattle', 'Cells, Cultured', 'Endothelium, Vascular', 'Rhodamine 123', 'Rhodamines', 'Tritium', 'Vincristine'] | 8,890,933 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['B01.050'], ['A07.035', 'A08.186.211.035'], ['A08.186.211'], ['B01.050.150.900.649.313.500.380.271'], ['A1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genomic-assisted phylogenetic analysis and marker development for next generation soybean cyst nematode resistance breeding. | Soybean cyst nematode (SCN, Heterodera glycines Ichinohe) is a serious soybean pest. The use of resistant cultivars is an effective approach for preventing yield loss. In this study, 19,652 publicly available soybean accessions that were previously genotyped with the SoySNP50K iSelect BeadChip were used to evaluate the... | ['Animals', 'Chromosome Mapping', 'Chromosomes, Plant', 'DNA Copy Number Variations', 'Disease Resistance', 'Genetic Markers', 'Genome, Plant', 'Genomics', 'Genotype', 'Host-Parasite Interactions', 'Phylogeny', 'Plant Breeding', 'Plant Diseases', 'Polymerase Chain Reaction', 'Polymorphism, Single Nucleotide', 'Quantita... | 26,566,850 | [['B01.050'], ['E05.393.183'], ['A11.284.187.560', 'A18.005', 'G05.360.162.560'], ['G05.365.795.297.500'], ['C23.550.291.671', 'G12.450.564.250', 'G12.450.800.250', 'G15.630.250'], ['D23.101.387', 'G05.695.450'], ['G05.360.340.365'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['G05.380'], ['G16.527.200.400'], ['G0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Alfa-glucosidase-inhibiting activity of some Mexican plants used in the treatment of type 2 diabetes. | Type 2 diabetes is an endocrine disease, which accounts for 9% of deaths worldwide. The aim of oral therapy is to reach normoglycemia to prevent later complications. Among glucose-lowering medications, alpha-glucosidase inhibitors delay the absorption of ingested carbohydrates, reducing the postprandial glucose and ins... | ['Animals', 'Diabetes Mellitus, Type 2', 'Enzyme Inhibitors', 'Female', 'Glycoside Hydrolase Inhibitors', 'Male', 'Mexico', 'Phytotherapy', 'Plant Extracts', 'Plants, Medicinal', 'Rats', 'Rats, Wistar'] | 18,082,348 | [['B01.050'], ['C18.452.394.750.149', 'C19.246.300'], ['D27.505.519.389'], ['D27.505.519.389.320', 'D27.505.696.422.249'], ['Z01.107.567.589'], ['E02.190.755'], ['D20.215.784.500', 'D26.667'], ['B01.650.560'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900']] | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Real-time PCR quantification of plasma DNA in non-small cell lung cancer patients and healthy controls. | INTRODUCTION: Free-circulating DNA is present in minute amounts in plasma of healthy individuals, whereas increased levels are found in a number of malignant pathologies including non-small cell lung cancer (NSCLC). The objective of this research was the evaluation of the plasma DNA quantification capacity to distingui... | ['Carcinoma, Non-Small-Cell Lung', 'DNA', 'DNA, Neoplasm', 'Humans', 'Lung Neoplasms', 'Polymerase Chain Reaction', 'ROC Curve'] | 20,156,763 | [['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['D13.444.308'], ['D13.444.308.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E05.393.620.500'], ['E05.318.370.800.750', 'E05.318.740.872.750', 'N05.715.360.325.700.6... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A comparison of the minimum canal wall thickness remaining following preparation using two nickel-titanium rotary systems. | AIM: To examine in vitro whether Profile or Hero 642 nickel-titanium rotary instrument systems substantially reduce the minimum canal wall thickness present following root-canal preparation.METHODOLOGY: The canal anatomy of 26 mesial roots from mandibular molars with separate buccal and lingual canals was evaluated bef... | ['Analysis of Variance', 'Dental Alloys', 'Dental Pulp Cavity', 'Dentin', 'Equipment Design', 'Humans', 'Image Processing, Computer-Assisted', 'Linear Models', 'Nickel', 'Root Canal Preparation', 'Titanium', 'Tooth Apex'] | 12,950,579 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D25.339.208', 'J01.637.051.339.208'], ['A14.549.167.900.265'], ['A14.549.167.900.280'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Glucose and lipid metabolism in essential hypertension: effects of diuretics and ACE-inhibitors. | Various aspects of carbohydrate and lipid metabolism were studied in two groups of patients with mild hypertension before and after 6 months' treatment with either lisinopril (n = 10) or hydrochlorothiazide (n = 10). A significant reduction of arterial blood pressure was seen after both treatment regimens. Circulating ... | ['Blood Glucose', 'C-Peptide', 'Cholesterol', 'Cholesterol, HDL', 'Female', 'Humans', 'Hydrochlorothiazide', 'Hypertension', 'Insulin', 'Lipids', 'Lisinopril', 'Male', 'Middle Aged', 'Triglycerides'] | 8,281,530 | [['D09.947.875.359.448.500'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Biological characterization of an English granulovirus from the summer fruit tortrix moth, Adoxophyes orana. | Adoxophyes orana granulovirus (AdorGV) was isolated from overwintering larvae in an orchard in Kent, in the UK. The developmental time of each A. orana instar was determined by measuring the size of the head capsule. The susceptibility of the larvae to the English isolate of AdorGV was evaluated in laboratory bioassays... | ['Animals', 'Biological Assay', 'Granulovirus', 'Larva', 'Lepidoptera', 'Lethal Dose 50', 'Longevity', 'Pest Control, Biological', 'Time Factors'] | 17,967,464 | [['B01.050'], ['E05.091'], ['B04.280.065.249', 'B04.525.100.249'], ['B05.500.500', 'G07.345.500.550.500.500'], ['B01.050.500.131.617.720.500.500.937'], ['E05.940.402', 'G07.225.500', 'G07.690.773.875.750', 'G07.690.936.500.750'], ['G07.345.124.519', 'G07.540'], ['N06.850.780.200.650.650'], ['G01.910.857']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Association of LMP/TAP gene polymorphisms with tuberculosis susceptibility in Li population in China. | BACKGROUND: Tuberculosis (TB) is a contagious disease affected by multiple genetic and environmental factors. Several association studies have suggested that cellular immune response is vital for controlling and preventing of tuberculosis infection. Low molecular weight polypeptides (LMPs) and transporters with antigen... | ['Adult', 'Antigen Presentation', 'China', 'DNA Primers', 'Ethnic Groups', 'Female', 'Genes, MHC Class II', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Genotype', 'Geography', 'Haplotypes', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Polymorphism, Genetic', 'Tuberculosis'] | 22,427,944 | [['M01.060.116'], ['G12.119', 'G12.450.050.400.070'], ['Z01.252.474.164'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['M01.686.754', 'N01.224.317'], ['G05.360.340.024.340.610.600', 'G05.360.340.024.380.500.600', 'G12.500.500.600'], ['E05.393.385'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Polypharmacy in multiple sclerosis: relationship with fatigue, perceived cognition, and objective cognitive performance. | OBJECTIVE: Patients with multiple sclerosis (MS) commonly use a variety of medications to slow disease progression, alleviate symptoms, and treat comorbid conditions. Polypharmacy has been linked to adverse outcomes in other patient groups, but has not been studied extensively in MS. We investigated the impact of polyp... | ['Adult', 'Cognition', 'Cognition Disorders', 'Fatigue', 'Female', 'Humans', 'Male', 'Memory', 'Memory Disorders', 'Middle Aged', 'Multiple Sclerosis', 'Neuropsychological Tests', 'Polypharmacy', 'Surveys and Questionnaires'] | 24,745,782 | [['M01.060.116'], ['F02.463.188'], ['F03.615.250'], ['C23.888.369'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['C10.597.606.525', 'C23.888.592.604.529', 'F01.700.625'], ['M01.060.116.630'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['F04.711.513'], ['E02.319.698'], ['E0... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The cyclopean eye and its implications: vergence state and visual direction. | The cyclopean illusion (Hering, 1861) is an anomalous lateral shift in the apparent direction to a monocularly seen target, which arises when a change in vergence is made by the opposite (nonobserving) eye. Surprisingly, this directional illusion does not arise, when the observed target is an afterimage or an intermitt... | ['Afterimage', 'Eye Movements', 'Humans', 'Vision, Binocular', 'Visual Cortex'] | 3,250,087 | [['F02.463.593.932.073', 'G14.040'], ['G11.427.410.140', 'G14.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.932.885'], ['A08.186.211.200.885.287.500.571.735', 'A08.186.211.200.885.287.500.814.953']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Geographic distributions of motor neuron disease mortality and well water use in U.S. counties. | OBJECTIVE: We recently reported that U.S. mortality rates for motor neuron disease (MND) at the level of the state are associated with well water use. However, data at the state level may not accurately reflect data at the individual level. We therefore examined the association between MND mortality and well water use ... | ['Amyotrophic Lateral Sclerosis', 'Humans', 'Motor Neuron Disease', 'Prevalence', 'United States', 'Water Supply'] | 28,019,106 | [['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.574.562', 'C10.668.467'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['Z01.107.567.875'], ['... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Infection of myofibers contributes to increased pathogenicity during infection with an epidemic strain of chikungunya virus. | UNLABELLED: Chikungunya virus (CHIKV) is an alphavirus transmitted by mosquitoes that is known to cause severe arthritis and myositis in affected patients. The ongoing epidemic began in eastern Africa in 2004 and then spread to islands of the Indian Ocean, India, and Southeast Asia, ultimately afflicting millions. Duri... | ['Alphavirus Infections', 'Animals', 'Chikungunya Fever', 'Chikungunya virus', 'Cytokines', 'Disease Models, Animal', 'Fibroblasts', 'Genome, Viral', 'Inflammation Mediators', 'Interferon-beta', 'Mice', 'Mice, Knockout', 'Muscle Fibers, Skeletal', 'Recombination, Genetic'] | 24,335,291 | [['C01.920.500.078', 'C01.925.782.930.100'], ['B01.050'], ['C01.920.500.078.184', 'C01.925.081.198', 'C01.925.782.930.100.184'], ['B04.820.578.875.054.198'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A11.329.228'], ['G05.360.340.358.840'], ['D23.469'], ['D12... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Using Clinical Trial Simulators to Analyse the Sources of Variance in Clinical Trials of Novel Therapies for Acute Viral Infections. | BACKGROUND: About 90% of drugs fail in clinical development. The question is whether trials fail because of insufficient efficacy of the new treatment, or rather because of poor trial design that is unable to detect the true efficacy. The variance of the measured endpoints is a major, largely underestimated source of u... | ['Acute Disease', 'Clinical Trials as Topic', 'Computer Simulation', 'Humans', 'Influenza, Human', 'Models, Biological', 'Sensitivity and Specificity', 'Time Factors', 'Viral Load', 'Virus Diseases'] | 27,332,704 | [['C23.550.291.125'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['E05.599.395'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Phylogenetic position of the genus Gonocerca Manter, 1925 (Trematoda, Hemiuroidea), based on partial sequences of 28S rRNA gene and a reconsideration of taxonomic status of Gonocercinae Skrjabin et Guschanskaja, 1955. | Adult trematodes of the genus Gonocerca Manter, 1925, are parasites of marine fishes. Identification of the phylogenetic positions and a revision of the taxonomic status of the subfamily Gonocercinae Skrjabin et Guschanskaja, 1955 (Derogenidae) are the main purposes of this research article. Four Gonocerca species were... | ['Animals', 'DNA, Helminth', 'Fishes', 'Phylogeny', 'RNA, Ribosomal, 28S', 'Trematoda'] | 28,359,900 | [['B01.050'], ['D13.444.308.315'], ['B01.050.150.900.493'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.690'], ['B01.050.500.500.736.715']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Aberrant Subcellular Dynamics of Sigma-1 Receptor Mutants Underlying Neuromuscular Diseases. | The sigma-1 receptor (ó-1R) is an endoplasmic reticulum resident chaperone protein involved in a plethora of cellular functions, and whose disruption has been implicated in a wide range of diseases. Genetic analysis has revealed two ó-1R mutants involved in neuromuscular disorders. A point mutation (E102Q) in the ligan... | ['Animals', 'CHO Cells', 'Cricetinae', 'Cricetulus', 'Fibroblasts', 'Fluorescence Recovery After Photobleaching', 'Mice, Inbred C57BL', 'Models, Biological', 'Mutant Proteins', 'Neuromuscular Diseases', 'Receptors, sigma', 'Recombinant Fusion Proteins', 'Shab Potassium Channels', 'Subcellular Fractions', 'Transfection'... | 27,418,673 | [['B01.050'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['A11.329.228'], ['E05.196.712.516.600.393'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['E05.599.395'], ['D12.776.602'], ['C10.668'],... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of nitroimidazoles on neuronal cells in vitro. | Peripheral neuropathy is a significant dose-limiting side effect of the nitroimidazole drugs in vivo. We have thus undertaken a study on the mechanisms of nitroimidazole neurotoxicity in the cultured neuronal cell lines, PC-12 (rat pheochromocytoma) and NB4183 (mouse neuroblastoma). Cells were differentiated with eithe... | ['Animals', 'Axons', 'Cell Line', 'Etanidazole', 'Intermediate Filaments', 'Mice', 'Misonidazole', 'Neurons', 'Nitroimidazoles', 'Radiation-Sensitizing Agents', 'Rats'] | 2,523,881 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['A11.251.210'], ['D02.640.672.250', 'D03.383.129.308.658.250'], ['A11.284.430.214.190.750.410'], ['B01.050.150.900.649.313.992.635.505.500'], ['D02.640.672.530', 'D03.383.129.308.658.530'], ['A08.675', 'A11.671'], ['D02.640.672', '... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Some robust higher-level percepts for music. | We explored a range of higher-level percepts in music. Participants were asked to make two-alternative forced-choice judgments of extracts of instrumental music on various dipole categories, such as happy/sad or male/female. The consistency with which each stimulus was judged on a response category across listeners pro... | ['Acoustic Stimulation', 'Adolescent', 'Auditory Perception', 'Emotions', 'Factor Analysis, Statistical', 'Female', 'Humans', 'Male', 'Music', 'Psychoacoustics'] | 18,283,933 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.057'], ['F02.463.593.071', 'G07.888.125'], ['F01.470'], ['E05.318.740.400', 'N05.715.360.750.350', 'N06.850.520.830.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.602'], ['E01.370.382.375.060.530', 'E01.370.685.628', 'F04.096.753.628']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Identification of protective antigens by RNA interference for control of the lone star tick, Amblyomma americanum. | The lone star tick, Amblyomma americanum, vectors pathogens of emerging diseases of humans and animals in the United States. Currently, measures are not available for effective control of A. americanum infestations. Development of vaccines directed against tick proteins may reduce tick infestations and the transmission... | ['Animals', 'Antibody Formation', 'Antigens', 'Cattle', 'Female', 'Gene Expression Profiling', 'Gene Library', 'Ixodidae', 'Male', 'Polymorphism, Genetic', 'RNA Interference', 'Recombinant Proteins', 'Reverse Transcriptase Polymerase Chain Reaction', 'Ribosomal Proteins', 'Sequence Analysis, DNA', 'Threonine-tRNA Ligas... | 20,018,267 | [['B01.050'], ['G12.450.050.370.250'], ['D23.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.393.332'], ['G05.360.325'], ['B01.050.500.131.166.132.832.400'], ['G05.365.795'], ['G05.308.203.374.790'], ['D12.776.828'], ['E05.393.620.500.725'], ['D12.776.835'], ['E05.393.760.700'], ['D08.811.464.263.200.800'], ['C01... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pulmonary edema secondary to chronic upper airway obstruction. Hemodynamic study in a child. | A 22-month-old girl with the syndrome of hypoventilation, pulmonary hypertension, cor pulmonale and pulmonary edema due to adenoidal hypertrophy is described. Adenoidectomy resulted in relief of all symptoms and signs within 24 h. Hemodynamic study using pulmonary artery catheter showed that the pulmonary artery pressu... | ['Female', 'Humans', 'Infant', 'Lung Diseases, Obstructive', 'Pulmonary Edema', 'Pulmonary Wedge Pressure'] | 6,512,078 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C08.381.495'], ['C08.381.742'], ['G09.330.380.076.695']] | ['Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Yellow mercuric oxide ointment and mercury intoxication. | Repeated cutaneous application of yellow mercuric oxide ointment for infected eczema resulted in mercury poisoning in a 4-month-old infant. Toxic levels of mercury were measured in blood, urine, cerebrospinal fluid and tissues. | ['Administration, Topical', 'Eczema', 'Humans', 'Infant', 'Male', 'Mercury', 'Mercury Compounds', 'Mercury Poisoning', 'Ointments', 'Oxides'] | 3,769,977 | [['E02.319.267.120'], ['C17.800.174.620', 'C17.800.815.620'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['D01.538'], ['C25.723.522.875'], ['D26.255.640'], ['D01.248.497.158.685', 'D01.650.550']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Adult peripheral neuroblastoma. | Report of clinical features, diagnostic and surgical aspects observed in a case of adult peripheral neuroblastoma infiltrative of the lumbosacral plexuses. The patient, a 39-year-old male, presented with sciatalgia and progressive crural monoplegia. Characteristic histological features of this rare tumor are described.... | ['Adult', 'Humans', 'Male', 'Neuroblastoma', 'Peripheral Nervous System Neoplasms', 'Tomography, X-Ray Computed'] | 1,807,241 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.600.590.650.550', 'C04.557.470.670.590.650.550', 'C04.557.580.625.600.590.650.550'], ['C04.588.614.596', 'C10.551.775', 'C10.668.829.725'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The role of industry in the development of a product for control of mycoplasmal plant diseases. | A number of mycoplasmal or mycoplasma-like diseases of plants have been treated with an oxytetracycline-based product. Remission of symptoms has generally resulted, and in some instances the local use of this product under temporary governmental registrations has been approved. The use of oxytetracycline for control of... | ['Biodegradation, Environmental', 'Drug Resistance, Microbial', 'Fruit', 'Mycoplasma', 'Oxytetracycline', 'Plant Diseases', 'Plants'] | 7,123,054 | [['N06.230.080.600.500', 'N06.850.460.375.500'], ['G06.225', 'G07.690.773.984.269'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['B03.440.860.580.553.553'], ['D02.455.426.559.847.562.900.600', 'D04.615.562.900.600'], ['G15.610'], ['B01.650']] | ['Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Zinc cytochrome c fluorescence as a probe for conformational changes in cytochrome c oxidase. | Zinc cytochrome c forms tight 1:1 complexes with a variety of derivatives of cytochrome c oxidase. On complex-formation the fluorescence of zinc cytochrome c is diminished. Titrations of zinc cytochrome c with cytochrome c oxidase, followed through the fluorescence emission of the former, have yielded both binding cons... | ['Cytochrome c Group', 'Cytochromes c', 'Electron Transport Complex IV', 'Energy Transfer', 'Fluorescent Dyes', 'Macromolecular Substances', 'Protein Binding', 'Protein Conformation', 'Spectrometry, Fluorescence', 'Spectrophotometry', 'Zinc'] | 2,827,630 | [['D08.244.286', 'D12.776.422.220.286'], ['D08.244.286.100', 'D12.776.422.220.286.100'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.250.875.304', 'D12.776.543.277.687', 'D12.776.543.585.450.250.875.484'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['D27.720.233.348', 'D27.720.470... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dragonflies community assembly in artificial habitats: Glimpses from field and manipulative experiments. | Several factors act on community structure, so determining species composition and abundance patterns. Core processes operating at local scales, such as species-environment matching and species interactions, shape observed assemblages. Artificial habitats (simplified structure) are useful systems for assessing the main... | ['Animals', 'Ecology', 'Ecosystem', 'Italy', 'Larva', 'Odonata', 'Predatory Behavior'] | 31,226,119 | [['B01.050'], ['H01.158.273.248', 'H01.277.249'], ['G16.500.275.157', 'N06.230.124'], ['Z01.542.489'], ['B05.500.500', 'G07.345.500.550.500.500'], ['B01.050.500.131.617.720.750.750'], ['F01.145.113.111.600', 'F01.145.113.252.520']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Occupational exposure to electromagnetic fields of uninterruptible power supply industry workers. | There is an increasing concern that exposure to extremely low-frequency (ELF) electromagnetic fields (EMFs) may cause or contribute to adverse health effects. To assess exposure to ELF EMFs, electric and magnetic field spot measurements were performed extensively at the workplace of a worldwide uninterruptible power su... | ['Electric Power Supplies', 'Electricity', 'Electromagnetic Fields', 'Humans', 'Occupational Exposure', 'Radiation Monitoring', 'Workplace'] | 24,366,245 | [['E07.305.124'], ['G01.358.500.249'], ['G01.358.500.260', 'G01.358.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.460.350.600'], ['E05.799.638', 'N06.850.780.375.700', 'N06.850.810.370'], ['N01.824.245.925', 'N04.452.677.975']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Blood pressure variability after intravenous thrombolysis in acute stroke does not predict intracerebral hemorrhage but poor outcome. | BACKGROUND: The relevance of blood pressure variability (BPV) in the development of intracerebral hemorrhage (ICH) after intravenous thrombolysis (IVT) in acute stroke still remains uncertain.METHODS: 427 consecutive patients treated with IVT in the years 2007-2009 were studied. Blood pressure (BP) values were analyzed... | ['Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Blood Pressure', 'Cerebral Hemorrhage', 'Disability Evaluation', 'Female', 'Fibrinolytic Agents', 'Germany', 'Humans', 'Infusions, Intravenous', 'Logistic Models', 'Male', 'Middle Aged', 'Odds Ratio', 'Predictive Value of Tests', 'Retrospective Studies', 'Risk Asse... | 22,179,586 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['E01.370.400'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Refusal of oral polio vaccine in northwestern Pakistan: a qualitative and quantitative study. | BACKGROUND: Refusal of the oral polio vaccine (OPV) is a difficulty faced by the Polio Eradication Initiative (PEI) in multiple endemic areas, including the Khyber Pakhtunkhwa Province (KPP), Pakistan. In 2007, we investigated community perceptions of the OPV and estimated the prevalence of OPV refusal in three distric... | ['Disease Eradication', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Mothers', 'Pakistan', 'Poliomyelitis', 'Poliovirus Vaccine, Oral', 'Religion', 'Treatment Refusal', 'Vaccination'] | 24,492,016 | [['N06.850.275'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M01.620.630'], ['Z01.252.245.723'], ['C01.207.618.750', 'C01.925.782.687.359.764', 'C10.228.228.618.750', 'C10.228.854.525.850', 'C10.668.864'], ['D20.21... | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Role of atrial natriuretic peptide in mediating the blood pressure-independent natriuresis elicited by systemic inhibition of nitric oxide. | While it is clearly recognized that increased intrarenal nitric oxide (NO) levels elicit natriuresis, confounding data showing that systemic nitric oxide synthase inhibition (NOSi) also increases sodium excretion (UNaV) poses a conundrum. This response has been attributed to the associated increases in arterial pressur... | ['Animals', 'Atrial Natriuretic Factor', 'Blood Pressure', 'Hemodynamics', 'Kidney', 'Male', 'Natriuresis', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Peptides, Cyclic', 'Rats', 'Rats, Sprague-Dawley', 'Sodium'] | 24,953,240 | [['B01.050'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.330.380'], ['A05.810.453'], ['G08.852.179.557'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['D08.811.682.664.500.772'], ['D04.345.566', 'D12.644.641'], ['B01.050.150.900.64... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neurological soft signs in individuals with schizotypal personality features. | OBJECTIVE: The current study attempted to examine the prevalence of neurological soft signs and their relationships with schizotypal traits in individuals with psychometrically defined schizotypal personality disorder (SPD) features.METHOD: Sixty-four individuals with SPD-proneness and 51 without SPD-proneness were rec... | ['Analysis of Variance', 'Endophenotypes', 'Female', 'Humans', 'Male', 'Neurologic Examination', 'Personality Inventory', 'Psychiatric Status Rating Scales', 'Psychometrics', 'Schizotypal Personality Disorder', 'Surveys and Questionnaires', 'Young Adult'] | 20,815,666 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G05.695.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.376.550', 'E01.370.600.550'], ['F04.711.647.513'], ['F04.711.513.653'], ['F04.711.780'], ['F03.675.725'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['M... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Failure of a novel ceramic-on-ceramic hip resurfacing prosthesis. | We report the early failure of five ceramic-on-ceramic hip resurfacings (CoCHRs). The ceramic used for the acetabular liner was a novel ceramic-composite (two thirds polyurethane and one third alumina ceramic). All cases were revised for increasing metal ion levels (blood cobalt 3.93-208.0 ìg/l and chromium 1.57-17.5 ì... | ['Adult', 'Aluminum Oxide', 'Arthroplasty, Replacement, Hip', 'Biocompatible Materials', 'Ceramics', 'Chromium', 'Cobalt', 'Corrosion', 'Female', 'Heavy Metal Poisoning', 'Hip Prosthesis', 'Humans', 'Metals, Heavy', 'Middle Aged', 'Poisoning', 'Prosthesis Failure'] | 25,453,631 | [['M01.060.116'], ['D01.056.050', 'D01.650.550.050'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['J01.637.153'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['G02.165'], ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Cholesterol-Lowering Effect of Calcium Alginate in Rats. | We examined whether calcium alginate (Ca-Alg) reduces blood cholesterol levels in rats fed a high-cholesterol diet. First, we examined taurocholate adsorption in vitro by various types of sodium alginate (Na-Alg). High molecular-weight, guluronic acid-rich Na-Alg showed the greatest adsorption of taurocholate, and ther... | ['Alginates', 'Animals', 'Cholesterol', 'Dietary Fats', 'Dose-Response Relationship, Drug', 'Epichlorohydrin', 'Glucuronic Acid', 'Hexuronic Acids', 'Hypercholesterolemia', 'Hypolipidemic Agents', 'Imidazoles', 'Lipid Metabolism', 'Male', 'Random Allocation', 'Rats', 'Rats, Wistar', 'Resins, Synthetic', 'Specific Patho... | 26,725,428 | [['D09.698.068'], ['B01.050'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.355.291.411.400'], ['D02.241.081.844.915.162.249', 'D02.241.152.811.162.500', 'D02.241.511.902.915.162.500', 'D09.811... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Developmental trends of eating disorder symptoms and comorbid internalizing symptoms in children and adolescents. | OBJECTIVE: To determine when gender differences in disordered eating symptoms emerge, when correlations between disordered eating and internalizing symptoms develop, and whether the relationship between internalizing and disordered eating symptoms varies based on age and/or gender.METHOD: We used questionnaire data fro... | ['Adolescent', 'Age Distribution', 'Anxiety', 'Child', 'Comorbidity', 'Depression', 'Feeding and Eating Disorders', 'Female', 'Humans', 'Male', 'Sex Distribution', 'Surveys and Questionnaires'] | 24,854,818 | [['M01.060.057'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['F01.470.132'], ['M01.060.406'], ['N05.715.350.225', 'N06.850.490.687'], ['F01.145.126.350'], ['F03.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.240.800', 'N01.224.803', 'N06.850.505.400.850'], ['E05.318.308.980', 'N05.715.360.30... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Molecular cloning and sequence of the complementary DNA encoding human mitochondrial acetoacetyl-coenzyme A thiolase and study of the variant enzymes in cultured fibroblasts from patients with 3-ketothiolase deficiency. | Complementary DNAs encoding the precursor of human hepatic mitochondrial acetoacetyl-CoA thiolase (T2) (EC 2.3.1.9) were cloned and sequenced. The cDNA inserts in these clones were 1,518 bases in length when overlapped, and encoded the 427-amino acid precursor of this enzyme (45,199 mol wt). This amino acid sequence in... | ['Acetyl-CoA C-Acetyltransferase', 'Acetyl-CoA C-Acyltransferase', 'Amino Acid Sequence', 'Base Sequence', 'Blotting, Northern', 'Cloning, Molecular', 'DNA', 'Gene Expression', 'Humans', 'Mitochondria', 'Molecular Sequence Data', 'Mutation', 'RNA, Messenger'] | 1,979,337 | [['D08.811.913.050.134.025'], ['D08.811.913.050.080'], ['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.393.220'], ['D13.444.308'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.4... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Beyond the DSM: development of a transdiagnostic psychiatric neuroscience course. | OBJECTIVE: Clinical and neurobiological data suggest that psychiatric disorders, as traditionally defined in the Diagnostic and Statistical Manual of Mental Disorders (DSM), are (1) more comorbid than expected by chance, (2) often share neurobiological signatures, and (3) reflect alterations across multiple brain syste... | ['Curriculum', 'Diagnostic and Statistical Manual of Mental Disorders', 'Humans', 'Internship and Residency', 'Mental Disorders', 'National Institute of Mental Health (U.S.)', 'Neurosciences', 'Psychiatry', 'United States'] | 24,493,358 | [['I02.158'], ['L01.453.245.945.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['F03'], ['I01.409.418.750.600.650.496.460', 'N03.540.052.750.460', 'N03.540.348.500.500.600.650.496.460'], ['H01.158.610'], ['F04.096.544', 'H02.403.690'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
International scientific collaboration in HIV and HPV: a network analysis. | Research endeavours require the collaborative effort of an increasing number of individuals. International scientific collaborations are particularly important for HIV and HPV co-infection studies, since the burden of disease is rising in developing countries, but most experts and research funds are found in developed ... | ['Coinfection', 'Cooperative Behavior', 'Developed Countries', 'Developing Countries', 'HIV', 'HIV Infections', 'Humans', 'Income', 'Papillomaviridae', 'Papillomavirus Infections', 'Prevalence', 'Research Personnel', 'Social Class'] | 24,682,041 | [['C01.218'], ['F01.145.813.115'], ['I01.615.500.250'], ['I01.615.500.300'], ['B04.820.650.589.650.350'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.417'], ['B04.280.210.655', 'B04... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Kinematic impact of anteromedial and posterolateral bundle graft fixation angles on double-bundle anterior cruciate ligament reconstructions. | BACKGROUND: Currently in double-bundle anterior cruciate ligament (ACL) reconstructions, the range of knee flexion angles that surgeons use for anteromedial (AM) and posterolateral (PL) bundle graft fixation spans from 0 degrees to 90 degrees for both bundle grafts. Despite the recent popularity of this procedure, no c... | ['Anterior Cruciate Ligament', 'Biomechanical Phenomena', 'Cadaver', 'Humans', 'Joint Instability', 'Orthopedic Procedures', 'Tenodesis', 'Validation Studies as Topic'] | 20,675,649 | [['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['G01.154.090', 'G01.374.089'], ['C23.550.260.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['E02.718', 'E04.555'], ['E04.555.710', 'E04.987.775.900'], ['E05.337.925', 'N05.715.360.335.500']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Safety and quality outcomes in peritoneal surface malignancy patients: developing a national center for excellence in Colombia. | BACKGROUND: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS + HIPEC) is being used more frequently for the treatment of peritoneal surface malignancies. There are a paucity of data regarding safety and quality outcomes in this group of patients. The aim of this study was to evaluate safety even... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Chemotherapy, Adjuvant', 'Chemotherapy, Cancer, Regional Perfusion', 'Combined Modality Therapy', 'Cytoreduction Surgical Procedures', 'Female', 'Follow-Up Studies', 'Humans', 'Hyperthermia, Induced', 'Length of Stay', 'Male', 'Middle Aged', 'Neoplasm... | 25,239,004 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.186.170', 'E02.319.170'], ['E02.319.267.200', 'E04.292.425'], ['E02.186'], ['E04.166'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of ethanol on the rat brain: ultrastructural alterations in the temporal cortex and in the hippocampus. | Male rats were submitted either to an oral alcohol intoxication or to chronological aging. Nervous morphometry shows that chronic alcohol consumption induces an increase in the proportion of neurons with dense cytoplasm and an increase of the synaptic cleft affecting principally synapses with spherical vesicles. The ce... | ['Aging', 'Alcoholism', 'Animals', 'Capillaries', 'Hippocampus', 'Humans', 'Male', 'Microscopy, Electron', 'Rats', 'Rats, Inbred Strains', 'Synapses', 'Temporal Lobe'] | 4,040,376 | [['G07.345.124'], ['C25.775.100.250', 'F03.900.100.350'], ['B01.050'], ['A07.015.461.165'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402', 'E05.595.402'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.0... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Denitrification as an important taxonomic marker within the genus Halomonas. | We have made a comprehensive study of the denitrifying species of the genus Halomonas, evaluating both the phylogenetic and phenotypic relationships amongst them and other species of Halomonas. The phylogenetic analysis was based on the 16S rRNA gene sequence as well as those of the three genes essential to a complete ... | ['Bacterial Proteins', 'Bacterial Typing Techniques', 'Base Composition', 'Cluster Analysis', 'DNA, Bacterial', 'DNA, Ribosomal', 'Halomonas', 'Molecular Sequence Data', 'Nitrates', 'Nitrites', 'Nitrogen', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA'] | 20,106,623 | [['D12.776.097'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['G02.111.080'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['D13.444.308.212'], ['D13.444.308.475'], ['B03.440.400.425.377.500', 'B03.660.250.350.500'], ['L01.453.245.667'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Attention competition with advertisement. | In the new digital age, information is available in large quantities. Since information consumes primarily the attention of its recipients, the scarcity of attention is becoming the main limiting factor. In this study, we investigate the impact of advertisement pressure on a cultural market where consumers have a limit... | ['Advertising', 'Attention', 'Compulsive Behavior', 'Models, Theoretical'] | 25,314,476 | [['J01.219.687.274', 'L01.143.050'], ['F02.830.104.214'], ['F01.145.527.100'], ['E05.599']] | ['Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
[Prokaryotic expression and bioactivity identification of Fab against human gamma-seminoprotein]. | AIM: To construct the expression vector containing cDNA encoding Fab against human gamma-seminoprotein and express it in E. coli.METHODS: The genes encoding K chain and Fd against gamma-seminoprotein were acquired from pUC19-K and pBluescript KS( M13-)-Fd by restrictive enzyme digestion and then cloned into the express... | ['Animals', 'Humans', 'Immunoblotting', 'Immunoglobulin Fab Fragments', 'Immunohistochemistry', 'Mice', 'Prostate-Specific Antigen'] | 15,169,664 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320'], ['D12.644.541.500.650', 'D12.776.124.486.485.680.650', 'D12.776.124.790.651.680.650', 'D12.776.377.715.548.680.650'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512'... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Charcot's arthropathy of the spine following spinal cord injury. A report of five cases. | Between 1955 and 1968, we treated five patients who had post-traumatic Charcot's arthropathy of the spine. All of the patients had a neurologically complete spinal-cord lesion. A laminectomy was implicated as the cause in four of the five patients. Spinal arthrodesis was used successfully to correct the deformity, stab... | ['Adult', 'Arthropathy, Neurogenic', 'Female', 'Humans', 'Laminectomy', 'Male', 'Middle Aged', 'Radiography', 'Spinal Cord Injuries', 'Spinal Diseases', 'Spinal Fusion'] | 3,997,930 | [['M01.060.116'], ['C05.550.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.718.563', 'E04.188.400', 'E04.525.450', 'E04.555.350'], ['M01.060.116.630'], ['E01.370.350.700'], ['C10.228.854.763', 'C10.900.850', 'C26.819'], ['C05.116.900'], ['E04.555.100.700']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Anatomic principles as a prerequisite for the diagnosis of knee-ligament injuries in skiing]. | The anatomy of the capsulo-ligamentous structures is most important because of its immense significance for the physiology of the knee joint and its high danger to lesions. On the other hand there exists new knowledge of anatomy which leads to a revision of the importance of the clinical findings. It must be emphasized... | ['Athletic Injuries', 'Humans', 'Knee', 'Knee Injuries', 'Knee Joint', 'Ligaments, Articular', 'Skiing'] | 838,431 | [['C26.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.450'], ['C26.558.554'], ['A02.835.583.475'], ['A02.513.514', 'A02.835.583.512', 'A10.165.669.514'], ['I03.450.642.845.787.500']] | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Effect of reduced training frequency on muscular strength. | Twenty-four men and 26 women (25 +/- 5 years) participating in 10 weeks (n = 27) and 18 weeks (n = 23) of variable resistance strength training programs were recruited to complete 12 weeks of reduced training. Training consisted of one set of 7-10 bilateral knee extensions performed to volitional failure. Prior to the ... | ['Adult', 'Body Composition', 'Female', 'Humans', 'Knee', 'Male', 'Muscles', 'Physical Education and Training', 'Weight Lifting'] | 3,246,465 | [['M01.060.116'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.450'], ['A02.633', 'A10.690'], ['I02.233.543'], ['I03.450.642.845.950']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Effect of insulin-plus-glucose infusion with or without epinephrine on fasting hyperkalemia. | Extrarenal potassium disposal is an important defense against hyperkalemia in patients with end-stage renal disease. Both insulin and epinephrine are important modulators of this process. Hemodialysis patients are prone to developing hyperkalemia during fasting. We tested the hypothesis that the infusion of physiologic... | ['Adult', 'Blood Glucose', 'Epinephrine', 'Fasting', 'Female', 'Glucose', 'Humans', 'Hyperkalemia', 'Infusions, Intravenous', 'Insulin', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Potassium', 'Propranolol', 'Renal Dialysis'] | 8,433,561 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Focal and diffuse visual field defects: their relationship to intraocular pressure. | The view that visual field loss in "low-tension" glaucoma (LTG) is more focal than in ordinary or "high-tension" glaucoma (HTG) is controversial. The basis of the controversy may be the inappropriate presupposition that an arbitrary intraocular pressure (IOP) level effectively differentiates these entities. We attempte... | ['Aged', 'Female', 'Fundus Oculi', 'Glaucoma', 'Humans', 'Intraocular Pressure', 'Male', 'Optic Disk', 'Optic Nerve Diseases', 'Vision Disorders', 'Visual Fields'] | 8,233,314 | [['M01.060.116.100'], ['A09.371.729.313'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['A08.800.800.120.680.660', 'A09.371.729.690'], ['C10.292.700', 'C11.640'], ['C10.597.751.941', 'C11.966', 'C23.888.592.763.941'], ['F02.463.593.932.934', 'G14.950']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison of diagnostic and relapse flow cytometry phenotypes in childhood acute lymphoblastic leukemia: implications for residual disease detection: a report from the children's oncology group. | BACKGROUND: Flow cytometric analysis of minimal residual disease (MRD) depends on detecting phenotypically abnormal populations. However, little is known about how phenotypic shifts between diagnosis and relapse affect MRD detection in childhood acute lymphoid leukemia (ALL).METHODS: We compared diagnostic and relapse ... | ['Child', 'Cohort Studies', 'Flow Cytometry', 'Follow-Up Studies', 'Humans', 'Medical Oncology', 'Neoplasm, Residual', 'Phenotype', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma', 'Recurrence', 'Sensitivity and Specificity', 'Treatment Outcome'] | 16,184,615 | [['M01.060.406'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Severe pollution of PCDD/Fs and dioxin-like PCBs in sediments from Lake Shihwa, Korea: tracking the source. | Concentrations of polychlorinated dibenzo-p-dioxins, dibenzofurans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (DL-PCBs) were determined in surface sediments from Lake Shihwa and from creeks that discharge into this artificial lake. The toxic equivalents (TEQs) in sediments ranged from 1.0 to 1770 pg/g dry weig... | ['Benzofurans', 'Dioxins', 'Environmental Monitoring', 'Geologic Sediments', 'Lakes', 'Polychlorinated Biphenyls', 'Polychlorinated Dibenzodioxins', 'Republic of Korea', 'Water Pollutants, Chemical', 'Water Pollution, Chemical'] | 22,980,772 | [['D03.633.100.127'], ['D02.309.500', 'D03.383.231'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.330', 'G16.500.320'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['D02.309.750', 'D02.455.426.559.389.185.698', 'D02.455.526.439.773'], ['D02.309.500.450', 'D03.633.300.786'], ['Z01.252.474.557.75... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Neonatal sepsis and mortality in a regional hospital in Trinidad: aetiology and risk factors. | A total of 132 neonatal deaths among 627 infants admitted to the neonatal ward of the San Fernando General Hospital, Trinidad over a 2-year period were reviewed. The most common cause of death was prematurity (43.9%). Infection was the second most common cause (21.2%). Pseudomonas aeruginosa and Staphylococcus aureus w... | ['Ampicillin', 'Bacterial Infections', 'Ceftazidime', 'Cross Infection', 'Drug Therapy, Combination', 'Female', 'Gentamicins', 'Hospital Mortality', 'Hospitals, Rural', 'Humans', 'Infant Mortality', 'Infant, Newborn', 'Infant, Premature', 'Male', 'Pseudomonas Infections', 'Staphylococcal Infections', 'Trinidad and Toba... | 11,284,241 | [['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['C01.150.252'], ['D02.065.589.099.249.210.150', 'D02.886.665.074.210.150', 'D03.633.100.300.249.210.150'], ['C01.248', 'C23.550.291.875.500'], ['E02.319.310'], ['D09.408.051.374'], ['E05.318.308.985.550.400', 'N01.224.935.698.4... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The influenza virus-induced fusion of erythrocyte ghosts does not depend on osmotic forces. | The role of osmotic forces and cell swelling in the influenza virus-induced fusion of unsealed or resealed ghosts of human erythrocytes was investigated under isotonic and hypotonic conditions using a recently developed fluorescence assay (Hoekstra, D., De Boer, T., Klappe, K., Wilschut, J. (1984) Biochemistry 23, 5675... | ['Erythrocyte Membrane', 'Erythrocytes', 'Humans', 'Hydrogen-Ion Concentration', 'Influenza A virus', 'Membrane Fusion', 'Osmotic Pressure'] | 3,415,984 | [['A11.118.290.270', 'A11.284.149.356', 'A15.145.229.334.270'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['B04.820.480.968.405.400'], ['G04.575'], ['G01.374.715.578', 'G02.640.249', 'G02.723.661']] | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of buprenorphine and norbuprenorphine in urine and hair by gas chromatography-mass spectrometry. | Buprenorphine, which is used in France as a substitution drug for opioid addiction, is widely abused, and several fatal cases have been reported. In order to confirm a recent intoxication or to establish retrospectively chronic abuse, a simple and reliable gas chromatographic-mass spectrometric method was developed and... | ['Adult', 'Buprenorphine', 'Female', 'Gas Chromatography-Mass Spectrometry', 'Hair', 'Humans', 'Male', 'Middle Aged', 'Narcotics', 'Sensitivity and Specificity', 'Substance Abuse Detection'] | 10,445,490 | [['M01.060.116'], ['D03.132.577.249.150', 'D03.605.497.150', 'D03.633.400.686.150', 'D04.615.723.795.150'], ['E05.196.181.349.500', 'E05.196.566.500'], ['A17.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D27.505.696.277.600', 'D27.505.696.663.850.014.760', 'D27.505.954.427.040.550', 'D2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Adenovirus virus-associated RNAs induce type I interferon expression through a RIG-I-mediated pathway. | The current study demonstrates that adenovirus virus-associated RNA (VA) is recognized by retinoic acid-inducible gene I (RIG-I), a cytosolic pattern recognition receptor, and activates RIG-I downstream signaling, leading to the induction of type I interferons (IFNs), similarly to Epstein-Barr virus-encoded small RNA. ... | ['Adenoviridae', 'DEAD Box Protein 58', 'DEAD-box RNA Helicases', 'Herpesvirus 4, Human', 'Humans', 'Interferon Type I', 'RNA, Messenger', 'RNA, Viral', 'Time Factors'] | 21,248,047 | [['B04.280.030'], ['D08.811.913.696.445.735.720.249.750'], ['D08.811.913.696.445.735.720.249'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', 'D23.529.374.440.890'], ['D13.444.735... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
How do parents' depression and anxiety, and infants' negative temperament relate to parent-infant face-to-face interactions? | The present study investigated the associations of mothers' and fathers' lifetime depression and anxiety symptoms, and of infants' negative temperament with parents' and infants' gaze, facial expressions of emotion, and synchrony. We observed infants' (age between 3.5 and 5.5 months, N = 101) and parents' gaze and faci... | ['Adult', 'Anxiety', 'Child of Impaired Parents', 'Depression', 'Female', 'Humans', 'Infant', 'Infant Behavior', 'Male', 'Parent-Child Relations', 'Parents', 'Temperament', 'Young Adult'] | 27,580,868 | [['M01.060.116'], ['F01.470.132'], ['M01.106'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.145.179.500'], ['F01.829.263.370.290'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['F01.752.898'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Baseline neutrophil-to-lymphocyte ratio is associated with long-term T2D remission after metabolic surgery. | AIMS: Metabolic surgery is considered as a therapeutic option for obese patients with type 2 diabetes (T2D). In order to identify novel laboratory variables that could improve the selection of patients who might greatly benefit from a surgical approach, we focused on the neutrophil-to-lymphocyte ratio (NLR) as a predic... | ['Bariatric Surgery', 'Blood Glucose', 'Body Mass Index', 'Diabetes Mellitus, Type 2', 'Female', 'Follow-Up Studies', 'Glycated Hemoglobin A', 'Humans', 'Italy', 'Leukocyte Count', 'Lymphocytes', 'Male', 'Middle Aged', 'Neutrophils', 'Obesity', 'Pilot Projects', 'Prognosis', 'Remission Induction', 'Time Factors', 'Trea... | 30,993,529 | [['E02.650.500.062', 'E04.062'], ['D09.947.875.359.448.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C18.452.394.750.149', 'C19.246.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D09.400.430.937', 'D12.776.124.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Pathogenesis of canine bordetellosis. | Bordetella bronchiseptica produced tracheobronchitis when administered in aerosol to specific pathogen-free dogs. Clinical signs appeared to be directly related to numbers of bacteria in the trachea. Electron microscopic examination revealed that each bacterium was close to one or more tracheal cilia and that a fibrill... | ['Aerosols', 'Alcaligenes', 'Animals', 'Antigens, Bacterial', 'Bacterial Vaccines', 'Bordetella', 'Bordetella Infections', 'Cilia', 'Dogs', 'Germ-Free Life', 'Immunization', 'Nasal Mucosa', 'Pasteurella', 'Pseudomonas aeruginosa', 'Respiratory System', 'Staphylococcus aureus', 'Trachea'] | 404,367 | [['D20.280.055', 'D26.255.165.055'], ['B03.440.400.425.115.050', 'B03.660.075.090.344.050'], ['B01.050'], ['D23.050.161'], ['D20.215.894.135'], ['B03.440.400.425.115.425', 'B03.660.075.090.344.425'], ['C01.150.252.400.143'], ['A11.284.180.165'], ['B01.050.150.900.649.313.750.250.216.200'], ['G06.320'], ['E02.095.465.42... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
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