Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Investigations of the peripheral vascular mechanisms implicated in congestive heart failure by the non-invasive evaluation of radial artery compliance and reactivity. | The viscoelastic, muscular and endothelial components of the vessel wall may be altered in patients with congestive heart failure (CHF). In order to investigate the relative contribution of each of these components to the peripheral vascular mechanisms of the disease, we have studied post-ischemic (endothelial-dependen... | ['Blood Pressure', 'Case-Control Studies', 'Cold Temperature', 'Elasticity', 'Endothelium, Vascular', 'Female', 'Heart Failure', 'Humans', 'Hyperemia', 'Ischemia', 'Male', 'Middle Aged', 'Muscle, Smooth, Vascular', 'Neurotransmitter Agents', 'Nitroglycerin', 'Photoplethysmography', 'Pressure', 'Radial Artery', 'Signal ... | 8,894,786 | [['E01.370.600.875.249', 'G09.330.380.076'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G01.374.590'], ['A07.015.700.500', 'A10.272.491.355'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Characterization of responders and nonresponders to tiaprofenic acid and naproxen in the treatment of patients with osteoarthritis. | OBJECTIVE: To characterize responders/nonresponders to 2 nonsteroidal antiinflammatory drugs by a combination of start variables in the treatment of patients with osteoarthritis (OA) of the hip(s)/knee(s).METHODS: Two hundred eight patients participated in a 3-week randomized double blind parallel group trial.RESULTS: ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anti-Inflammatory Agents, Non-Steroidal', 'Discriminant Analysis', 'Double-Blind Method', 'Female', 'Humans', 'Male', 'Middle Aged', 'Naproxen', 'Osteoarthritis', 'Propionates', 'Treatment Outcome'] | 8,295,188 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['E05.318.740.350', 'N05.715.360.750.325', 'N06.850.520.830.350'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Saikosaponin a Inhibits Cigarette Smoke-Induced Oxidant Stress and Inflammatory Responses by Activation of Nrf2. | Saikosaponin a (SSa), a triterpenoid saponin, has numerous pharmacological properties, including anti-inflammatory and antioxidant effects. The purpose of this study was to investigate whether and how SSa protected against cigarette smoke (CS)-induced lung inflammation in mice. The mice were exposed to CS and SSa was a... | ['Animals', 'Cigarette Smoking', 'Heme Oxygenase-1', 'Membrane Proteins', 'Mice', 'NF-E2-Related Factor 2', 'Oleanolic Acid', 'Oxidative Stress', 'Pneumonia', 'Saponins', 'Smoke'] | 29,654,431 | [['B01.050'], ['F01.145.805.375.750', 'F01.145.958.875.750'], ['D08.811.682.690.708.410.500'], ['D12.776.543'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.260.108.737', 'D12.776.930.127.737'], ['D02.455.849.919.530.733', 'D02.455.849.919.650.600'], ['G03.673', 'G07.775.750'], ['C01.748.610', 'C08.381.677', ... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dispersal of Lutzomyia longipalpis and expansion of canine and human visceral leishmaniasis in S?o Paulo State, Brazil. | Visceral leishmaniasis (VL), a neglected disease, is a serious public health problem that affects millions of people worldwide. The objectives of the study were to evaluate the sensitivity of Lutzomyia longipalpis and canine VL (CVL) autochthony early detection and describe the spatial and temporal dispersal of vector ... | ['Animals', 'Brazil', 'Cities', 'Disease Progression', 'Disease Reservoirs', 'Dog Diseases', 'Dogs', 'Endemic Diseases', 'Humans', 'Insect Vectors', 'Leishmaniasis, Visceral', 'Neglected Diseases', 'Population Density', 'Psychodidae'] | 27,640,322 | [['B01.050'], ['Z01.107.757.176'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['C23.550.291.656'], ['N06.850.520.203.250'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['N06.850.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['C01.61... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Hypertension is a risk factor for fractures. | To study the effects of hypertension and other cardiovascular risk factors on risk of fractures, we carried out a case-control study including 124,655 fracture cases and 373,962 age- and gender-matched controls. The main exposure was hypertension, stroke, acute myocardial infarction, ischemic heart disease, atrial fibr... | ['Adult', 'Aged', 'Antihypertensive Agents', 'Atrial Fibrillation', 'Case-Control Studies', 'Female', 'Fractures, Bone', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Risk Factors', 'Stroke', 'Venous Thrombosis'] | 19,067,019 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.411.162'], ['C14.280.067.198', 'C23.550.073.198'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Stereotactic endovascular aortic navigation with a novel ultrasonic-based three-dimensional localization system. | BACKGROUND: Endovascular aortic procedures have been developed to treat many aortic diseases effectively. However, these procedures are also becoming increasingly complex given the development of branched or fenestrated endografts. Part of the difficulty lies in the limitations of current imaging paradigms. A more intu... | ['Animals', 'Aorta', 'Catheterization', 'Endovascular Procedures', 'Female', 'Fluoroscopy', 'Imaging, Three-Dimensional', 'Swine', 'Ultrasonography, Interventional'] | 23,375,138 | [['B01.050'], ['A07.015.114.056'], ['E02.148', 'E05.157'], ['E04.100.814.529', 'E04.502.382'], ['E01.370.350.700.225'], ['E01.370.350.400', 'L01.224.308.410'], ['B01.050.150.900.649.313.500.880'], ['E01.370.350.850.855', 'E04.502.890']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Stepwise histone replacement by SWR1 requires dual activation with histone H2A.Z and canonical nucleosome. | Histone variant H2A.Z-containing nucleosomes are incorporated at most eukaryotic promoters. This incorporation is mediated by the conserved SWR1 complex, which replaces histone H2A in canonical nucleosomes with H2A.Z in an ATP-dependent manner. Here, we show that promoter-proximal nucleosomes are highly heterogeneous f... | ['Adenosine Triphosphatases', 'Chromatin Assembly and Disassembly', 'Dimerization', 'Histones', 'Nucleosomes', 'Promoter Regions, Genetic', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins'] | 21,111,233 | [['D08.811.277.040.025'], ['G04.400.095', 'G05.213.095', 'G05.308.095'], ['G02.206', 'G03.230'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['A11.284.430.106.279.345.190.160.180.625', 'D12.776.664.224.550', 'G05.360.160.180.625'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of the bending behaviour of porcine xenograft leaflets and of natural aortic valve material: bending stiffness, neutral axis and shear measurements. | Flexibility of the materials used in the construction of bioprosthetic heart valves is essential for proper valve operation. We therefore examined the bending behaviour of glutaraldehyde treated porcine aortic valve cusps in comparison with fresh aortic valve tissue. We repeatedly bent a total of 35 strips of fresh and... | ['Animals', 'Aortic Valve', 'Biophysics', 'Bioprosthesis', 'Collagen', 'Elasticity', 'Equipment Design', 'Glutaral', 'Microscopy, Polarization', 'Models, Cardiovascular', 'Stress, Mechanical', 'Tensile Strength'] | 2,509,479 | [['B01.050'], ['A07.541.510.110'], ['H01.158.344', 'H01.671.100'], ['E07.695.100'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G01.374.590'], ['E05.320'], ['D02.047.532'], ['E01.370.350.515.624', 'E05.595.624'], ['E05.599.395.161'], ['G01.374.835'], ['G01.374.850']] | ['Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A longitudinal study of human papillomavirus 16 L1, e6, and e7 seropositivity and oral human papillomavirus 16 infection. | BACKGROUND: Individuals with human papillomavirus (HPV) infections can develop IgG antibodies to HPV proteins including the L1 capsid and E6 and E7 oncoproteins. Evidence on whether L1 antibodies reduce the risk of cervical HPV infection is mixed, but this has not been explored for oral HPV infections. Antibodies to HP... | ['Adult', 'Anus Neoplasms', 'Case-Control Studies', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Human papillomavirus 16', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Oncogene Proteins, Viral', 'Oropharyngeal Neoplasms', 'Papillomavirus E7 Proteins', 'Papillomavirus Infections', 'Prevalence', 'Represso... | 25,585,068 | [['M01.060.116'], ['C04.588.274.476.411.307.790.040', 'C06.301.371.411.307.790.040', 'C06.405.249.411.307.790.040', 'C06.405.469.491.307.790.040', 'C06.405.469.860.101.163', 'C06.405.469.860.180.500.040'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.478.566.350.170', 'E05.478.56... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Symptom-free intervals in sicklers: does pneumococcal vaccination and penicillin prophylaxis have a role? | To investigate the combined effect of pneumococcal vaccination and penicillin prophylaxis on the progress of sickle cell disease, two groups of sickle cell disease patients, presenting with severe clinical manifestations of the disease were selected as cohorts. One group was vaccinated with the polyvalent pneumococcal ... | ['Anemia, Sickle Cell', 'Bacterial Vaccines', 'Child', 'Child, Preschool', 'Humans', 'Infant', 'Penicillin G', 'Penicillin G Benzathine', 'Streptococcus pneumoniae', 'Vaccination'] | 2,355,405 | [['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['D20.215.894.135'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['D02.065.589.099.750.750', 'D02.886.108.750.750', 'D03.633.100.300.750.750'], ['D02.065.589.099.750.750.685... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of active navigation on object recognition in virtual environments. | We investigated the importance and efficiency of active and passive exploration on the recognition of objects in a variety of virtual environments (VEs). In this study, 54 participants were randomly allocated into one of active and passive navigation conditions. Active navigation was performed by allowing participants ... | ['Adult', 'Attention', 'Choice Behavior', 'Exploratory Behavior', 'Female', 'Humans', 'Male', 'Mental Recall', 'Orientation', 'Pattern Recognition, Visual', 'Reaction Time', 'User-Computer Interface'] | 17,474,852 | [['M01.060.116'], ['F02.830.104.214'], ['F02.463.785.373.346'], ['F01.145.387', 'F01.658.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['F01.058.577', 'F02.830.606'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['L01.22... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Accuracy of device-specific 2D and 3D image distortion correction algorithms for magnetic resonance imaging of the head provided by a manufacturer. | For the application of magnetic resonance imaging (MRI) in precision radiotherapy, image distortions must be reduced to a minimum to maintain geometrical accuracy. Recently, two-dimensional (2D) and three-dimensional (3D) algorithms for MRI-device-specific distortion corrections were developed by the manufacturers of M... | ['Algorithms', 'Artifacts', 'Equipment Design', 'Equipment Failure Analysis', 'Head', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Imaging, Three-Dimensional', 'Magnetic Resonance Imaging', 'Phantoms, Imaging', 'Reproducibility of Results', 'Sensitivity and Specificity'] | 16,757,858 | [['G17.035', 'L01.224.050'], ['E05.047'], ['E05.320'], ['E05.325.192'], ['A01.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.825.500'], ['E07.671'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Replantation for complete amputated finger composite lateral tissues]. | OBJECTIVE: To explore the clinical therapeutic effect and safety of application of Ilizarov technique combined with flap instant expansion technique in correcting tibia angular deformity combined with skin contracture by one stage.METHODS: From January 2010 to January 2013, 30 cases of tibial deformity with skin contra... | ['Adult', 'Amputation, Traumatic', 'Contracture', 'External Fixators', 'Female', 'Finger Injuries', 'Humans', 'Ilizarov Technique', 'Male', 'Middle Aged', 'Postoperative Complications', 'Replantation', 'Surgical Flaps', 'Treatment Outcome'] | 29,292,644 | [['M01.060.116'], ['C26.062'], ['C05.550.323', 'C05.651.197'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['C26.448.429'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.555.120.380', 'E04.555.300.380'], ['M01.060.116.630'], ['C23.550.767'], ['E04.936.494'], ['A10.850.710', 'E07.862.710'], ['E01.789.800', ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Characterization of the calmodulin-binding sites of muscle phosphofructokinase and comparison with known calmodulin-binding domains. | Calmodulin has been shown to interact with high affinity with muscle phosphofructokinase (Mayr, G. W. (1984) Eur. J. Biochem. 143, 513-520, 521-529). In this study, direct binding measurements indicated that each of the two subunits of dimeric phosphofructokinase bound two calmodulins with Kd values of about 3 nM and 1... | ['Amino Acid Sequence', 'Amino Acids', 'Animals', 'Binding Sites', 'Brain', 'Calmodulin', 'Cattle', 'Kinetics', 'Macromolecular Substances', 'Models, Molecular', 'Molecular Weight', 'Muscles', 'Peptide Fragments', 'Phosphofructokinase-1', 'Protein Binding', 'Protein Conformation', 'Rabbits'] | 2,954,960 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125'], ['B01.050'], ['G02.111.570.120'], ['A08.186.211'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['B01.050.150.900.649.313.500.380.271'], ['G01.374.661', 'G02.111.490'], ['D05'], ['E05.599.595'], ['G02.494'], ['A02.633', 'A10.690'], ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The relationship between pelagic larval duration and range size in tropical reef fishes: a synthetic analysis. | We address the conflict in earlier results regarding the relationship between dispersal potential and range size. We examine all published pelagic larval duration data for tropical reef fishes. Larval duration is a convenient surrogate for dispersal potential in marine species that are sedentary as adults and that ther... | ['Age Factors', 'Animals', 'Demography', 'Environment', 'Geography', 'Larva', 'Linear Models', 'Oceans and Seas', 'Perciformes', 'Population Dynamics', 'Species Specificity'] | 16,007,745 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['G16.500.275', 'N06.230'], ['H01.277.500'], ['B05.500.500', 'G07.345.500.550.500.500'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.8... | ['Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Membrane permeabilization of the African horse sickness virus VP5 protein is mediated by two N-terminal amphipathic á-helices. | The VP5 outer capsid protein of African horse sickness virus (AHSV) is cytotoxic when expressed in Spodoptera frugiperda (Sf-9) cells. Secondary structure analysis of the VP5 amino acid sequence of AHSV-9 identified two N-terminal amphipathic á-helices within the first 43 amino acids. Baculovirus expression of N- and C... | ['African Horse Sickness Virus', 'Animals', 'Capsid Proteins', 'Cell Line', 'Cell Membrane Permeability', 'Protein Structure, Secondary', 'Spodoptera', 'Virulence Factors'] | 21,193,936 | [['B04.820.223.719.550.050'], ['B01.050'], ['D12.776.964.970.600.550'], ['A11.251.210'], ['G03.143.335', 'G04.175'], ['G02.111.570.820.709.600'], ['B01.050.500.131.617.720.500.500.937.650.700'], ['D23.946.896']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Real-time three-dimensional echocardiographic left heart parameters in healthy indian adults. | OBJECTIVE: Cardiac chamber dimensions are race and anthropometry dependent. We determined the age and gender specific 3-Dimensional echocardiographic (3DE) reference values for dimensions and function of left ventricle (LV) and left atrium (LA) in normal Indian adults.METHODS: This single center prospective study enrol... | ['Adolescent', 'Adult', 'Aged', 'Atrial Function, Left', 'Echocardiography, Three-Dimensional', 'Female', 'Follow-Up Studies', 'Heart Atria', 'Heart Ventricles', 'Humans', 'India', 'Male', 'Middle Aged', 'Prospective Studies', 'Reference Values', 'Time Factors', 'Ventricular Function, Left', 'Young Adult'] | 30,392,502 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G09.330.040.100'], ['E01.370.350.130.750.230', 'E01.370.350.400.200', 'E01.370.350.850.220.230', 'E01.370.370.380.220.230'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A07.541.358'], ['A07.541.560'], ['B01.050.15... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Variation characteristics of maize yield and fertilizer utilization rate on an upland yellow soil under long term fertilization]. | An analysis was made on the 16-year experimental data from the long term fertilization, experiment of maize on a yellow soil in Guizhou of Southwest China. Four treatments, i. e. , no fertilization (CK), chemical fertilization (165 kg N x hm(-2), 82.5 kg P2O5 x hm(-2), and 82.5 kg K2O x hm(-2), NPK), organic manure (30... | ['Biomass', 'China', 'Ecosystem', 'Fertilizers', 'Soil', 'Time Factors', 'Tropical Climate', 'Zea mays'] | 24,483,072 | [['G16.500.275.157.100', 'N06.230.124.100'], ['Z01.252.474.164'], ['G16.500.275.157', 'N06.230.124'], ['D27.720.031.400'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['G01.910.857'], ['G16.500.275.071.600', 'N06.230.300.100.250.600'], ['B01.650.940.800.575.912.250.822.966']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Male-biased miR-92 from early chicken embryonic gonads directly targets ATRX and DDX3X. | MiR-17-92 cluster consists of multifunctional miRNAs related to gonadal development in mammals. Our preliminary data showed that gga-miR-92 was male-biased in chicken embryonic gonads at E5.5 and E6.5. MiR-92(a-2) and two putative targets (ATRX and DDX3X) were highly conserved and located on mammalian Chromosome X but ... | ["3' Untranslated Regions", 'Animals', 'Cells, Cultured', 'Chick Embryo', 'DEAD-box RNA Helicases', 'Female', 'Fibroblasts', 'Gene Expression Regulation, Developmental', 'Gonads', 'Male', 'MicroRNAs', 'Wnt Proteins'] | 28,554,548 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['B01.050'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['D08.811.913.696.445.735.720.249'], ['A11.329.228'], ['G05.308.310'], ['A05.360.576', 'A06.300.312'], ['D13.150.650.319', 'D13.444.735.150... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sulfidation as a natural antidote to metallic nanoparticles is overestimated: CuO sulfidation yields CuS nanoparticles with increased toxicity in medaka (Oryzias latipes) embryos. | Sulfidation is considered as a natural antidote to toxicity of metallic nanoparticles (NPs). The detoxification contribution from sulfidation, however, may vary depending on sulfidation mechanisms. Here we present the dissolution-precipitation instead of direct solid-state-shell mechanism to illustrate the process of C... | ['Animals', 'Antidotes', 'Copper', 'Metal Nanoparticles', 'Oryzias', 'Oxidative Stress', 'Sulfides'] | 25,625,586 | [['B01.050'], ['D27.505.696.706.037', 'D27.720.799.037'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['J01.637.512.600.500'], ['B01.050.150.900.493.850.139.650'], ['G03.673', 'G07.775.750'], ['D01.248.497.158.874', 'D01.875.350.850', 'D02.886.520']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Improvements in complex mixture analysis by NMR: DQF-COSY iDOSY. | Diffusion-ordered NMR spectroscopy (DOSY NMR) is a highly useful tool for the study of complex mixtures via NMR. Often, spectral overlap limits the ability of obtaining cleanly separated subspectra of the components due to inherently instable multiexponential fits or data inversion procedures. Three-dimensional DOSY va... | ['DNA', 'Magnetic Resonance Spectroscopy', 'Sensitivity and Specificity'] | 17,328,528 | [['D13.444.308'], ['E05.196.867.519'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[18F-FDG PET cerebral imaging for localizing epileptogenic foci and its relation to predicting operative outcome]. | OBJECTIVE: To find out the relationship between FDG PET image pattern and epileptogenic focus localization and predict prognosis by comparing pre- and post-surgical FDG images with operative effects.METHODS: 72 patients with epilepsy who underwent surgery (49M, 23F, aged 24.3 years on average) were studied with pre-sur... | ['Adult', 'Cerebral Cortex', 'Epilepsy', 'Female', 'Fluorine Radioisotopes', 'Fluorodeoxyglucose F18', 'Humans', 'Male', 'Tomography, Emission-Computed'] | 11,718,077 | [['M01.060.116'], ['A08.186.211.200.885.287.500'], ['C10.228.140.490'], ['D01.496.749.340'], ['D09.254.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.350.800', 'E01.370.350.600.350.800', 'E01.370.350.710.800', 'E01.370.350.825.800', 'E01.370.384.730.800']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Transcervical intralesional vasopressin injection in hysteroscopic myomectomy--description of a new technique. | An original technique of transcervical intralesional vasopressin injection that allowed direct infiltration to submucous myomas under hysteroscopic control is described. Five patients with a symptomatic submucous myoma 1.5-5 cm in size scheduled for hysteroscopic myomectomy were recruited. The time required for vasopre... | ['Adult', 'Cervix Uteri', 'Female', 'Humans', 'Hysteroscopy', 'Injections, Intralesional', 'Middle Aged', 'Uterine Myomectomy', 'Vasoconstrictor Agents', 'Vasopressins'] | 23,343,201 | [['M01.060.116'], ['A05.360.319.679.256'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.378.330', 'E01.370.388.250.360', 'E04.502.250.360', 'E04.520.360', 'E04.950.300.539'], ['E02.319.267.530.430'], ['M01.060.116.630'], ['E04.950.300.941'], ['D27.505.954.411.793'], ['D06.472.699.631.692.781', 'D12.644.40... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genetic control of extracellular protease synthesis in the yeast Yarrowia lipolytica. | Depending on the pH of the growth medium, the yeast Yarrowia lipolytica secretes an acidic protease or an alkaline protease, the synthesis of which is also controlled by carbon, nitrogen, and sulfur availability, as well as by the presence of extracellular proteins. Previous results have indicated that the alkaline pro... | ['Amino Acid Sequence', 'Aspartic Acid Endopeptidases', 'Fungal Proteins', 'Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Fungal', 'Hydrogen-Ion Concentration', 'Molecular Sequence Data', 'Mutation', 'Sequence Alignment', 'Signal Transduction', 'Yarrowia'] | 11,861,549 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D08.811.277.656.074.500', 'D08.811.277.656.300.048'], ['D12.776.354'], ['G05.308.320'], ['G05.308.330'], ['G02.300'], ['L01.453.245.667'], ['G05.365.590'], ['E05.393.751'], ['G02.111.820', 'G04.835'], ['B01.300.107.795.980', 'B01.300.930.980']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The use of on-line UV photoreduction in the flow analysis determination of dissolved reactive phosphate in natural waters. | A highly sensitive flow analysis manifold for rapid determination of dissolved reactive phosphate was developed which uses ethanol and UV light to reduce phosphomolybdic acid, instead of the reactive and short-lived chemical reductants typically employed in molybdenum blue chemistry. This reaction is impractical to per... | ['Environmental Monitoring', 'Equipment Design', 'Flow Injection Analysis', 'Limit of Detection', 'Molybdenum', 'Oxidation-Reduction', 'Phosphates', 'Solubility', 'Ultraviolet Rays', 'Water'] | 25,435,242 | [['N06.850.460.350.080', 'N06.850.780.375'], ['E05.320'], ['E05.196.460'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['D01.268.556.555', 'D01.268.956.500', 'D01.552.544.555'], ['G02.700', 'G03.295.531'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.695.625.675.650'], ['G0... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of pretransplant hepatitis C virus RNA status on posttransplant outcome. | Undetectable hepatitis C virus (HCV) RNA [RNA(-)] before liver transplantation (OLT) has been shown to decrease the rates of disease recurrence. We sought to determine whether RNA(-) subjects differ in post-OLT recurrence (virological/VR, histological/HR), graft failure (GF), or patient survival from RNA(+) patients us... | ['Adult', 'Aged', 'Female', 'Graft Survival', 'Hepacivirus', 'Hepatitis C', 'Humans', 'Liver Transplantation', 'Male', 'Middle Aged', 'RNA, Viral', 'Recurrence', 'Retrospective Studies', 'Survival Rate', 'Treatment Outcome', 'Viral Load'] | 18,589,127 | [['M01.060.116'], ['M01.060.116.100'], ['G12.875.545.340'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['M01.0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Disseminated intravascular coagulation in elective primary total hip replacement. | Acute disseminated intravascular coagulation is a common and potentially serious complication of many clinical conditions, including trauma. We report two cases in which this condition occurred after routine elective primary total hip replacement. | ['Acute Disease', 'Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Hip', 'Disseminated Intravascular Coagulation', 'Humans', 'Male'] | 10,065,735 | [['C23.550.291.125'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['C15.378.100.220', 'C15.378.463.250', 'C15.378.925.220'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Monocular advantage for face perception implicates subcortical mechanisms in adult humans. | The ability to recognize faces accurately and rapidly is an evolutionarily adaptive process. Most studies examining the neural correlates of face perception in adult humans have focused on a distributed cortical network of face-selective regions. There is, however, robust evidence from phylogenetic and ontogenetic stud... | ['Adolescent', 'Adult', 'Facial Expression', 'Female', 'Humans', 'Male', 'Nerve Net', 'Photic Stimulation', 'Reaction Time', 'Vision, Monocular', 'Visual Cortex', 'Visual Perception', 'Young Adult'] | 24,236,767 | [['M01.060.057'], ['M01.060.116'], ['E01.370.600.225', 'F01.145.209.530.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.511'], ['E05.723.729'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.463.593.932.893'], ['A08.186.211.200.885.287.500.571.735', 'A08.186.211.200.885.287.500.814.95... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Wolbachia infection and mitochondrial diversity in the canine heartworm (Dirofilaria immitis). | BACKGROUND AND AIMS: Many species of filarial nematodes are infected with Wolbachia pipientis, a maternally inherited endosymbiont. In addition to manipulating host reproduction, these bacteria also affect the evolution of the mitochondrial DNA with which they are transmitted. Selective sweeps can establish a single mi... | ['Animals', 'Carnivora', 'DNA, Helminth', 'DNA, Mitochondrial', 'Dirofilaria immitis', 'Genetic Variation', 'North America', 'Wolbachia'] | 21,171,866 | [['B01.050'], ['B01.050.150.900.649.313.750'], ['D13.444.308.315'], ['D13.444.308.283.225'], ['B01.050.500.500.294.400.937.463.230.300'], ['G05.365'], ['Z01.107.567'], ['B03.660.050.783.500.762']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Wet corn gluten feed as a supplement for lactating dairy cattle and growing heifers. | A lactation trial and a heifer growth trial were conducted to evaluate use of wet corn gluten feed by dairy herds. Twelve multiparous and 4 primiparous Holsteins were assigned to 4 x 4 Latin squares blocked according to previous production or parity. Animals received increasing amounts of wet corn gluten feed, up to 36... | ['Animal Feed', 'Animals', 'Cattle', 'Dietary Proteins', 'Female', 'Glutens', 'Lactation', 'Pregnancy', 'Zea mays'] | 3,392,310 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['D12.776.765.433.500.500', 'D12.776.765.725.500.500'], ['G08.686.523', 'G08.686.702.500'], ['G08.686.784.769'], ['B01.650.940.800.575.912.250.822.966']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Detection of antibody to epizootic diarrhea of infant mice (EDIM) virus. | Cultured mouse liver cells containing either eipzootic diarrhea of infant mice viral antigen or Nebraska calf diarrhea vaccine virus antigen were equally effective for detecting serum antibody to epizootic diarrhea of infant mice virus by immunofluorescence. The presence of rotavirus in infant mouse intestinal suspensi... | ['Animals', 'Animals, Suckling', 'Antibodies, Viral', 'Antigens, Viral', 'Cells, Cultured', 'Enzyme-Linked Immunosorbent Assay', 'Mice', 'Rodent Diseases', 'Rotavirus', 'Rotavirus Infections'] | 6,316,027 | [['B01.050'], ['B01.050.050.293'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D23.050.327'], ['A11.251'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B01.050.150.900.649.313.992.635.505.500']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cardiac molecular markers of programmed cell death are activated in end-stage heart failure patients supported by left ventricular assist device. | BACKGROUND: Cardiomyocyte apoptosis increases in heart failure (HF) and is implicated in disease progression. The apoptotic cell is not inevitably committed to death, and appropriate therapy like left ventricular assist device (LVAD) support could offer a rescue of cellular functions. Literature data regarding the modu... | ['Adult', 'Apoptosis', 'Biomarkers', 'Blotting, Western', 'Female', 'Heart Failure', 'Heart-Assist Devices', 'Humans', 'Immunohistochemistry', 'In Situ Nick-End Labeling', 'Male', 'Middle Aged', 'Real-Time Polymerase Chain Reaction', 'Ventricular Remodeling'] | 24,856,512 | [['M01.060.116'], ['G04.146.954.035'], ['D23.101'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C14.280.434'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.7... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Turbidimetric immunoassay of serum C-reactive protein. | This rapid, reliable equilibrium turbidimetric immunoassay for serum C-reactive protein involves a potent monospecific antibody. Polyethylene glycol-6000 to accelerate and enhance the immunoprecipitation reaction, and Tween-20 surfactant to lower and stabilize the sample blank values. Grossly lipemic, icteric, or hemol... | ['C-Reactive Protein', 'Humans', 'Immunoassay', 'Immunodiffusion', 'Nephelometry and Turbidimetry', 'Spectrophotometry, Ultraviolet'] | 6,812,987 | [['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566', 'E05.601.470'], ['E01.370.225.812.735.645.350', 'E05.200.812.735.645.350', 'E05.478.594.760.645.350', 'E05.478.605.492.350'], ['E05.196.712.650'], ['E05.196.712.726.802', 'E05.196.867.826... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of menadione, a reactive oxygen generator, on leukotriene secretion from RBL-2H3 cells. | Reactive oxygen species (ROS) are produced in various cells and affect many biological processes. We previously reported that 2-methyl-1,4-naphtoquinone (menadione) inhibited Ca(2+) influx from the extracellular medium and exocytosis evoked by antigen stimulation in the mast cell line, RBL-2H3. Mast cells release vario... | ['Anti-Inflammatory Agents', 'Antigens', 'Arachidonate 5-Lipoxygenase', 'Biological Transport', 'Calcium', 'Cell Line', 'Cytoplasm', 'Extracellular Signal-Regulated MAP Kinases', 'Humans', 'Leukotriene C4', 'Mast Cells', 'Nuclear Envelope', 'Phosphorylation', 'Reactive Oxygen Species', 'Vitamin K 3', 'p38 Mitogen-Activ... | 20,460,770 | [['D27.505.954.158'], ['D23.050'], ['D08.811.682.690.416.583.500.055', 'D12.776.556.579.374.568.500.020'], ['G03.143'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251.210'], ['A11.284.430.214'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.169'], ['B01.050.150.900.64... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
DNA vaccination against Theiler's murine encephalomyelitis virus leads to alterations in demyelinating disease. | Although the etiology of multiple sclerosis (MS) is not known, several factors play a role in this disease: genetic contributions, immunologic elements, and environmental factors. Viruses and virus infections have been associated with the initiation and/or enhancement of exacerbations in MS. Theiler's murine encephalom... | ['Animals', 'Antibodies, Viral', 'Blotting, Western', 'Brain', 'Capsid', 'Capsid Proteins', 'DNA, Viral', 'Disease Models, Animal', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Humans', 'Mice', 'Multiple Sclerosis', 'Muscles', 'Spinal Cord', 'Theilovirus', 'Vaccination', 'Vaccines, DNA', 'Viral Vaccines'] | 9,882,300 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A08.186.211'], ['A21.249.500.250'], ['D12.776.964.970.600.550'], ['D13.444.308.568'], ['C22.232', 'E05.598.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Recurrent ovarian cancer: is there a role for re-treatment with bevacizumab after an initial complete response to a bevacizumab-containing regimen? | OBJECTIVE: To compare the progression free survival (PFS) and overall survival (OS) in patients with epithelial ovarian cancer (EOC) who received Bev after Bev (BAB) vs. those who were not re-treated with Bev (NOTBev) after initially experiencing a complete response (CR) to a Bev-containing regimen (BCR).METHODS: We pe... | ['Angiogenesis Inhibitors', 'Antibodies, Monoclonal, Humanized', 'Antineoplastic Combined Chemotherapy Protocols', 'Bevacizumab', 'Carcinoma, Ovarian Epithelial', 'Chemotherapy, Adjuvant', 'Female', 'Humans', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neoplasms, Glandular and Epithelial', 'Ovarian Neoplasms', 'Retro... | 22,885,866 | [['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D12.776.124.486.485.114.224.060.375', 'D12.776.124.790.651.114.224.060.4... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Analysis of incomplete gene expression dataset through protein-protein interaction information. | This paper shows a graph based method to analyze proteomic expression data. The method allows the prediction of the expression of genes not measured by the gene expression technology based on the local connectivity properties of the measured differentially expressed gene set. The prediction of the expression jointly wi... | ['Algorithms', 'Atherosclerosis', 'Electrophoresis, Gel, Two-Dimensional', 'Gene Expression Profiling', 'Gene Expression Regulation', 'Humans', 'Image Processing, Computer-Assisted', 'Lasers', 'Lipoproteins, LDL', 'Models, Genetic', 'Oligonucleotide Array Sequence Analysis', 'Protein Interaction Mapping', 'Proteomics',... | 22,255,911 | [['G17.035', 'L01.224.050'], ['C14.907.137.126.307'], ['E05.196.401.250', 'E05.301.300.230'], ['E05.393.332'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E07.632.490', 'E07.710.520'], ['D10.532.515', 'D12.776.521.550'], ['E05.599.395.397'], ['E05.393.661.640', 'E05.393.760.640', 'E... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Flavisolibacter ginsengiterrae gen. nov., sp. nov. and Flavisolibacter ginsengisoli sp. nov., isolated from ginseng cultivating soil. | Two strains (Gsoil 492(T) and Gsoil 643(T)) isolated in Pocheon Province, South Korea, from soil used for ginseng cultivation were characterized using a polyphasic approach. Both isolates comprised Gram-negative, aerobic, non-motile, rod-shaped bacteria. They had similar chemotaxonomic characteristics, e.g. containing ... | ['Bacteroidetes', 'DNA, Bacterial', 'DNA, Ribosomal', 'Fatty Acids', 'Molecular Sequence Data', 'Panax', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Soil Microbiology'] | 17,684,267 | [['B03.440.080'], ['D13.444.308.212'], ['D13.444.308.475'], ['D10.251'], ['L01.453.245.667'], ['B01.650.940.800.575.912.250.087.500'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.686.670'], ['H01.158.273.540.274.555', 'N06.850.425.300']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Radial nerve conduction in patients with carpal tunnel syndrome. | Orthodromic sensory nerve conduction was studied in the distal segment of the superficial radial nerve in 50 cases of carpal tunnel syndrome in 41 patients. In patients aged 50 years or less, the mean conduction velocity was 48.6 m/s (SD +/- 4.8), and the mean amplitude of the sensory action potential was 9.7 microV (S... | ['Adult', 'Aged', 'Carpal Tunnel Syndrome', 'Electric Stimulation', 'Evoked Potentials', 'Fingers', 'Humans', 'Median Nerve', 'Middle Aged', 'Motor Neurons', 'Neural Conduction', 'Radial Nerve'] | 7,347,158 | [['M01.060.116'], ['M01.060.116.100'], ['C10.668.829.500.500.200', 'C10.668.829.550.200', 'C26.844.150.206'], ['E05.723.402'], ['G07.265.216.500', 'G11.561.200.500'], ['A01.378.800.667.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800.720.050.500'], ['M01.060.116.630'], ['A08.675.655.500', 'A11.671.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Risk of Depressive Symptoms Associated with Morbidity in Postpartum Women in Rural Bangladesh. | Objectives Depression following pregnancy is common, but its extent and association with maternal morbidity in the first 6 months postpartum have not been well described in low resource settings such as rural Bangladesh. Methods We used data from a population-based, community trial of approximately 39,000 married rural... | ['Adolescent', 'Adult', 'Bangladesh', 'Depression', 'Female', 'Humans', 'Mothers', 'Population Surveillance', 'Postpartum Period', 'Pregnancy', 'Rural Population', 'Stress Disorders, Post-Traumatic', 'Stress, Psychological', 'Young Adult'] | 28,766,094 | [['M01.060.057'], ['M01.060.116'], ['Z01.252.245.131'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M01.620.630'], ['E05.318.308.980.438.700', 'N05.715.360.300.800.438.625', 'N06.850.520.308.980.438.700', 'N06.850.780.675'], ['G08.686... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Antimicrobial potential of actinobacteria isolated from the rhizosphere of the Caatinga biome plant Caesalpinia pyramidalis Tul. | Actinobacteria are known to produce various secondary metabolites having antibiotic effects. This study assessed the antimicrobial potential of actinobacteria isolated from the rhizosphere of Caesalpinia pyramidalis Tul. from the Caatinga biome. Sixty-eight actinobacteria isolates were evaluated for antimicrobial activ... | ['Actinobacteria', 'Anti-Bacterial Agents', 'Antifungal Agents', 'Bacillus subtilis', 'Biological Products', 'Caesalpinia', 'Candida albicans', 'Fusarium', 'Microbial Sensitivity Tests', 'Phylogeny', 'Rhizosphere', 'Staphylococcus aureus'] | 26,985,927 | [['B03.510.024', 'B03.510.460.400.400.049'], ['D27.505.954.122.085'], ['D27.505.954.122.136'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.460.410.158.218.725'], ['D20.215'], ['B01.650.940.800.575.912.250.401.093'], ['B01.300.107.795.095.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Role of the DNA methyltransferase variant DNMT3b3 in DNA methylation. | Several alternatively spliced variants of DNA methyltransferase (DNMT) 3b have been described. Here, we identified new murine Dnmt3b mRNA isoforms and found that mouse embryonic stem (ES) cells expressed only Dnmt3b transcripts that contained exons 10 and 11, whereas the Dnmt3b transcripts in somatic cells lacked these... | ['Alternative Splicing', 'Animals', 'Azacitidine', 'Blotting, Southern', 'Blotting, Western', 'CpG Islands', 'DNA (Cytosine-5-)-Methyltransferase 1', 'DNA (Cytosine-5-)-Methyltransferases', 'DNA Methylation', 'Decitabine', 'Embryo, Mammalian', 'Enzyme Inhibitors', 'Exons', 'HCT116 Cells', 'Humans', 'Isoenzymes', 'Mice'... | 14,757,847 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['B01.050'], ['D02.145.150', 'D03.383.742.680.245.217', 'D13.570.685.245.217', 'D13.570.800.286.300'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of UHPLC and HPLC in benzodiazepines analysis of postmortem samples: a case-control study. | The aim of this study was to compare system efficiency and analysis duration regarding the solvent consumption and system maintenance in high-pressure liquid chromatography (HPLC) and ultra high-pressure liquid chromatography (UHPLC). In a case-control study, standard solutions of 7 benzodiazepines (BZs) and 73 biologi... | ['Autopsy', 'Benzodiazepines', 'Case-Control Studies', 'Chromatography, High Pressure Liquid', 'Humans'] | 25,860,209 | [['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['D03.633.100.079.080'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
[Setting up a quality improvement plan on patient paging in an orthopedic ward]. | Answering the patient's paging is a daily activity in patient care which is rarely identified and recognized. This can cause dissatisfaction of the patients and caregivers. A Quality Improvement Plan on paging was set up in an orthopedic ward to identify the reasons for paging so as to anticipate the requests, and impr... | ['Hospital Communication Systems', 'Humans', 'Orthopedics', 'Patient Satisfaction', "Patients' Rooms", 'Professional-Patient Relations'] | 19,195,349 | [['N02.278.216.500.937', 'N04.452.442.452.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.810.494'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.600'], ['N02.278.220.640'], ['F01.829.401.650', 'N05.300.660']] | ['Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Tuberculous peritonitis defying diagnosis: report of a case. | A case of tuberculous peritonitis, which has been scarcely encountered in clinical practice in recent years, is reported. A 32-year-old man was admitted to our hospital complaining of abdominal fullness, anorexia, and a 15 kg weight loss. His abdomen was distended. There was neither any previous history nor recent cont... | ['Adult', 'Antitubercular Agents', 'Biopsy', 'Follow-Up Studies', 'Humans', 'Laparotomy', 'Male', 'Peritoneum', 'Peritonitis', 'Peritonitis, Tuberculous', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 10,819,487 | [['M01.060.116'], ['D27.505.954.122.085.255'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
VFDB 2012 update: toward the genetic diversity and molecular evolution of bacterial virulence factors. | The virulence factor database (VFDB, http://www.mgc.ac.cn/VFs/) has served as a comprehensive repository of bacterial virulence factors (VFs) for >7 years. Bacterial virulence is an exciting and dynamic field, due to the availability of complete sequences of bacterial genomes and increasing sophisticated technologies f... | ['Bacteria', 'Databases, Genetic', 'Evolution, Molecular', 'Genetic Variation', 'Phylogeny', 'Virulence Factors'] | 22,067,448 | [['B03'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['G05.045.250', 'G16.075.250'], ['G05.365'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D23.946.896']] | ['Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Outcome analysis of surgery for Blount disease. | BACKGROUND: The purpose of this study was to evaluate the results of surgery for Blount disease using a patient-derived outcome assessment. Our hypothesis was that an outcome score that quantitates the patient's level of satisfaction should correlate with specific ranges of correction for those radiologic variables tra... | ['Barbados', 'Bone Diseases, Developmental', 'Child', 'Female', 'Humans', 'Linear Models', 'Male', 'Pain Measurement', 'Patient Satisfaction', 'Radiography', 'Surveys and Questionnaires', 'Tibia', 'Treatment Outcome', 'Trinidad and Tobago'] | 20,104,154 | [['Z01.107.084.900.140', 'Z01.639.880.140'], ['C05.116.099'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['E01.370.600.550... | ['Geographicals [Z]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Preoperative predictors of returning to work following primary total knee arthroplasty. | BACKGROUND: There is little in the literature to guide clinicians in advising patients regarding their return to work following a primary total knee arthroplasty. In this study, we aimed to identify which factors are important in estimating a patient's time to return to work following primary total knee arthroplasty, h... | ['Adolescent', 'Adult', 'Aged', 'Arthroplasty, Replacement, Knee', 'Employment', 'Female', 'Humans', 'Male', 'Middle Aged', 'Motivation', 'Occupations', 'Pain Measurement', 'Prospective Studies', 'Recovery of Function', 'Surveys and Questionnaires', 'Survival Analysis', 'Time Factors', 'Work Capacity Evaluation'] | 21,209,263 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['N01.824.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.658', 'F01.752.543.500.750'], ['N01.824.547'], ['E01.370.600.550.324'], ['E05.318.372.500.750.625', 'N05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Taltirelin alleviates fatigue-like behavior in mouse models of cancer-related fatigue. | Fatigue affects most cancer patients and has numerous potential causes, including cancer itself and cancer treatment. Cancer-related fatigue (CRF) is not relieved by rest, can decrease quality of life, and has no FDA-approved therapy. Thyrotropin-releasing hormone (TRH) has been proposed as a potential novel treatment ... | ['Animals', 'Antimetabolites, Antineoplastic', 'Cell Line, Tumor', 'Colonic Neoplasms', 'Disease Models, Animal', 'Fatigue', 'Female', 'Fluorouracil', 'Gamma Rays', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Nootropic Agents', 'Receptors, Thyrotropin-Releasing Hormone', 'Thyrotropin... | 28,720,519 | [['B01.050'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['A11.251.210.190', 'A11.251.860.180'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.8... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pharmacokinetic evaluation of pancreatic arterial infusion chemotherapy with lipid emulsion as a drug carrier in an animal model. | The purpose of this study was to investigate the potential pharmacokinetic advantage of pancreatic arterial infusion chemotherapy with lipid emulsion as a drug carrier for pancreatic cancer in a dog model. The 20% Intralipid, as a solvent, was used in the experimental animals with 2 ml/kg (group A) and 1 ml/kg (group B... | ['Animals', 'Antineoplastic Agents', 'Cisplatin', 'Dogs', 'Drug Carriers', 'Emulsions', 'Fat Emulsions, Intravenous', 'Infusions, Intra-Arterial', 'Models, Animal', 'Pancreas', 'Pancreatic Neoplasms', 'Phospholipids', 'Soybean Oil', 'Splenic Artery'] | 22,475,761 | [['B01.050'], ['D27.505.954.248'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['B01.050.150.900.649.313.750.250.216.200'], ['D26.255.260', 'E02.319.300.380'], ['D20.280.260', 'D26.255.165.260'], ['D26.255.165.260.270', 'D26.776.708.733.500', 'D27.505.954.578.733.500', 'D27.720.752.733.500'], ['E02.319.267.510.520']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Ethiopian parents' perception of their children's health: a focus group study of immigrants to Israel. | BACKGROUND: The recent influx of Ethiopian immigrants to Israel has created challenges for healthcare workers. Qualitative research methods have proven to be of value in providing useful data in cross-cultural medical settings.OBJECTIVE: To learn about Ethiopian immigrants' perception of the health of their children.ME... | ['Child', 'Child Welfare', 'Cross-Cultural Comparison', 'Emigration and Immigration', 'Ethiopia', 'Female', 'Focus Groups', 'Health Services', 'Humans', 'Israel', 'Male', 'Medicine, Traditional', 'Parents'] | 11,794,918 | [['M01.060.406'], ['I01.880.787.293'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['I01.240.600.525.500', 'N01.224.625.525.500', 'N06.850.505.400.700.525.500'], ['Z01.058.290.120.310'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['N02.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Enterococcus faecium and Enterococcus durans isolated from cheese: Survival in the presence of medications under simulated gastrointestinal conditions and adhesion properties. | In this study, we evaluated the survival of Enterococcus faecium and Enterococcus durans, isolated from cheese, in the presence of medications and under simulated in vitro gastrointestinal conditions. The presence of genes encoding virulence factors, the susceptibility to antimicrobial agents, and adhesion properties w... | ['Animals', 'Anti-Bacterial Agents', 'Cheese', 'Enterococcus', 'Enterococcus faecium', 'Lactobacillus', 'Microbial Sensitivity Tests', 'Probiotics'] | 27,988,121 | [['B01.050'], ['D27.505.954.122.085'], ['G07.203.200.500.444', 'G07.203.300.350.300.444', 'J02.350.500.444', 'J02.500.350.300.444'], ['B03.353.750.250.250', 'B03.510.550.250.250'], ['B03.353.750.250.250.300', 'B03.510.550.250.250.300'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475', 'B03.510.550.450.475'], ['E0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Fine specificity analysis indicates that the primary and secondary fluorescein-specific cytotoxic T cell receptor repertoires are indistinguishable. | Previous data from this laboratory have shown that fluorescein-specific cytotoxic T cells derived from naive mice are capable of distinguishing between different isomeric forms of the fluorescein hapten, as well as between the iodoacetamido-, isothiocyanate- and dichlorotriazinyl amino-fluorescein derivatives. In this ... | ['Animals', 'Cells, Cultured', 'Cross Reactions', 'Epitopes', 'Female', 'Fluoresceins', 'Haptens', 'Immunologic Memory', 'Mice', 'Mice, Inbred BALB C', 'Rats', 'Receptors, Antigen, T-Cell', 'T-Lymphocytes, Cytotoxic', 'Tumor Cells, Cultured'] | 7,541,020 | [['B01.050'], ['A11.251'], ['G12.122.281'], ['D23.050.550'], ['D02.455.426.779.347', 'D03.633.300.953.275', 'D04.711.347'], ['D23.050.550.480'], ['G12.450.050.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['B01.050.150.900.649.313... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Burkholderia pseudomallei isolates from Sarawak, Malaysian Borneo, are predominantly susceptible to aminoglycosides and macrolides. | Melioidosis is a potentially fatal disease caused by the saprophytic bacterium Burkholderia pseudomallei. Resistance to gentamicin is generally a hallmark of B. pseudomallei, and gentamicin is a selective agent in media used for diagnosis of melioidosis. In this study, we determined the prevalence and mechanism of gent... | ['Aminoglycosides', 'Anti-Bacterial Agents', 'Burkholderia pseudomallei', 'Gentamicins', 'Macrolides', 'Malaysia', 'Microbial Sensitivity Tests'] | 24,145,517 | [['D09.408.051'], ['D27.505.954.122.085'], ['B03.660.075.090.688.100.600'], ['D09.408.051.374'], ['D02.540.505', 'D02.540.576.500', 'D04.345.674.500'], ['Z01.252.145.487'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Neonatal ovine uterine development involves alterations in expression of receptors for estrogen, progesterone, and prolactin. | Effects of age on uterine histoarchitecture, cell proliferation, and hormone receptor expression were determined for neonatal ewe lambs from birth (Postnatal Day [PND] 0) to PND 56. Uteri were histologically evaluated and proliferating cell nuclear antigen (PCNA), estrogen receptor alpha (ER-alpha), progesterone recept... | ['Animals', 'Animals, Newborn', 'Estradiol', 'Estrogen Receptor alpha', 'Female', 'Gene Expression Regulation, Developmental', 'Progesterone', 'Prolactin', 'Proliferating Cell Nuclear Antigen', 'Receptors, Estrogen', 'Receptors, Progesterone', 'Receptors, Prolactin', 'Sheep', 'Uterus'] | 10,993,845 | [['B01.050'], ['B01.050.050.282'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D12.776.826.750.350.174'], ['G05.308.310'], ['D04.210.500.745.745.654.829', 'D06.472.334.734.623', 'D06.472.334.851.687.750'], ['D06.472.699.322.576.773', 'D06.472.699.631.525.525', 'D12.644.548.691.525.525'], ['D12.776.660.740... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The activity of drug addiction service of the Russian Federation: an assessment of statistical parameters and an analysis of results]. | The authors studied changes in the structure of drug addiction services, the dynamics of outpatient and inpatient referrals for drug addiction treatment and effectiveness of drug addiction services in 2011 compared to the preceding period. There was a reduction of availability of drug treatment services due to the redu... | ['Benchmarking', 'Data Interpretation, Statistical', 'Health Care Surveys', 'Humans', 'Morbidity', 'Residential Treatment', 'Retrospective Studies', 'Russia', 'Substance Abuse Treatment Centers', 'Substance-Related Disorders'] | 23,887,460 | [['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Shear stress modulates the action of the 88 K protein-actin complex on actin polymerization. | An actin-regulatory protein, 88 K protein-actin complex (88 K-actin complex) isolated from porcine brain, increases the rate of actin polymerization as measured by viscometry which gives rise to shearing stresses. In contrast, when measured by the optical absorption method without solvent flow, the complex does not pro... | ['Actins', 'Animals', 'Brain Chemistry', 'Kinetics', 'Macromolecular Substances', 'Nerve Tissue Proteins', 'Rabbits', 'Spectrophotometry, Ultraviolet', 'Surface Properties', 'Swine', 'Viscosity'] | 7,068,567 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['G02.111.150', 'G03.185'], ['G01.374.661', 'G02.111.490'], ['D05'], ['D12.776.631'], ['B01.050.150.900.649.313.968.700'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['G02.860'], ['B01.050.150.900.649.313.500.880'], ['G02.930']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Local hemostasis in subarachnoid hemorrhage. | Fibrinopeptide A (FPA), platelet-secreted protein, platelet factor 4 and beta-thromboglobulin were determined in the cerebrospinal fluid of patients who had suffered from subarachnoid hemorrhage and were treated with 6 g tranexamic acid or 4 million KIU aprotinin to prevent rebleeding. Platelet-secreted proteins and FP... | ['Fibrinogen', 'Fibrinopeptide A', 'Humans', 'Ischemic Attack, Transient', 'Platelet Factor 4', 'Subarachnoid Hemorrhage', 'Tranexamic Acid', 'beta-Thromboglobulin'] | 2,957,204 | [['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['D12.644.200', 'D12.776.124.125.515', 'D12.776.124.270.310', 'D12.776.811.300.310', 'D23.101.340', 'D23.119.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.150.836', 'C14.907.253.092.836'], ['D12.644.276.374.20... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biliary atresia type I cyst and choledochal cyst [corrected]: can we differentiate or not? | BACKGROUND/PURPOSE: It is difficult to discriminate between choledochal cyst[corrected]with obstructive jaundice and biliary atresia with a cyst at the porta hepatis in neonates or young infants. This review evaluates whether it is possible to differentiate between these two diseases. We here also provide an overview o... | ['Biliary Atresia', 'Choledochal Cyst', 'Diagnosis, Differential', 'Diagnostic Imaging', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Postoperative Complications', 'Survival Rate'] | 23,579,998 | [['C06.130.120.123', 'C06.198.125', 'C16.131.314.125'], ['C04.182.198', 'C06.130.120.127', 'C06.198.184', 'C16.131.314.184'], ['E01.171'], ['E01.370.350'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.0... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Unmasking a functional allosteric domain in an allosterically nonresponsive carbamoyl-phosphate synthetase. | Although carbamoyl-phosphate synthetases (CPSs) share sequence identity, multidomain structure, and reaction mechanism, they have varying physiological roles and allosteric effectors. Escherichia coli CPS (eCPS) provides CP for both arginine and pyrimidine nucleotide biosynthesis and is allosterically regulated by meta... | ['Adenosine Diphosphate', 'Adenosine Triphosphate', 'Allosteric Regulation', 'Animals', 'Binding Sites', 'Carbon-Nitrogen Ligases', 'Escherichia coli', 'Humans', 'Inosine Monophosphate', 'Molecular Structure', 'Ornithine', 'Recombinant Fusion Proteins', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', '... | 12,244,118 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G02.111.044'], ['B01.050'], ['G02.111.570.120'], ['D08.811.464.259'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.988.400... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Frequency of macroscopic intradural hemorrhage with and without subdural hemorrhage in early childhood autopsies. | Some authors have suggested that in the fetus, neonate and infant, intradural hemorrhage (IDH) is relatively common and often presents alongside subdural hemorrhage (SDH). These authors have theorized that pediatric SDH may result from an IDH due to blood leakage from a dural vascular plexus. In this study, we report t... | ['Child, Preschool', 'Dura Mater', 'Female', 'Forensic Pathology', 'Hematoma, Subdural', 'Humans', 'Infant', 'Infant, Newborn', 'Intracranial Hemorrhages', 'Male', 'Observer Variation', 'Photography', 'Retrospective Studies'] | 30,915,608 | [['M01.060.406.448'], ['A08.186.566.395'], ['H02.403.330.300', 'H02.403.650.249', 'I01.198.780.937.460'], ['C10.228.140.300.535.450.400', 'C10.900.300.837.600', 'C14.907.253.573.400.450', 'C23.550.414.838.700', 'C23.550.414.913.700', 'C26.915.300.490.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703... | ['Named Groups [M]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Activity of (+)-cyclaradine (Sch 31172) against herpes simplex virus in vitro and in vivo. | (+)-Cyclaradine (Sch 31172) is the carbocyclic derivative of adenosine arabinoside (9-beta-D-arabinofuranosyladenine). Because it is not deaminated by deaminase in serum, as is adenosine arabinoside, (+)-cyclaradine is about 2 to 5 times more active in vitro against herpes simplex virus. (+)-Cyclaradine has in vitro ac... | ['Acyclovir', 'Animals', 'Cell Line', 'Coformycin', 'Female', 'Guinea Pigs', 'Herpes Simplex', 'Humans', 'Pentostatin', 'Simplexvirus', 'Vero Cells', 'Vidarabine'] | 3,032,089 | [['D03.633.100.759.758.399.454.250'], ['B01.050'], ['A11.251.210'], ['D03.383.742.680.350.200', 'D13.570.685.350.200', 'D13.570.800.410.200'], ['B01.050.150.900.649.313.992.550'], ['C01.925.256.466.382', 'C01.925.825.320', 'C17.800.838.790.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.742.680.350.20... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinical study of the month. The CAPPP study: "The Captopril Prevention Project"]. | The Captopril Prevention Project (CAPPP) was a prospective, randomized, open trial which aimed at comparing the prevention by captopril (n = 5492) or by a conventional treatment (n = 5493; diuretics or beta-blockers) of cardiovascular morbidity and mortality in patients with hypertension (diastolic blood pressure > 100... | ['Adrenergic beta-Antagonists', 'Adult', 'Aged', 'Angiotensin-Converting Enzyme Inhibitors', 'Captopril', 'Cardiovascular Diseases', 'Cerebrovascular Disorders', 'Diabetes Mellitus', 'Diuretics', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Treatment Outcome'] | 10,321,112 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.389.745.085'], ['D12.125.072.401.623.270'], ['C14'], ['C10.228.140.300', 'C14.907.253'], ['C18.452.394.750', 'C19.246'], ['D27.505.696.560.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.90... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Experimental characterization of magnetically focused electron contamination at the surface of a high-field inline MRI-linac. | PURPOSE: The fringe field of the Australian MRI-linac causes contaminant electrons to be focused along the central axis resulting in a high surface dose. This work aims to characterize this effect using Gafchromic film and high-resolution detectors, MOSkinTM and microDiamond. The secondary aim is to investigate the inf... | ['Electrons', 'Magnetic Phenomena', 'Magnetic Resonance Imaging', 'Particle Accelerators', 'Surface Properties'] | 31,633,212 | [['G01.249.335', 'G01.358.500.750'], ['G01.358'], ['E01.370.350.825.500'], ['E07.710.680'], ['G02.860']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A strategy for generating polyglutamine 'length libraries' in model host proteins. | Huntington's disease is one of nine known neurodegenerative diseases in which a disease-specific protein contains an unusually long polyglutamine (polyQ) stretch. The proteins associated with each disease are unrelated in sequence, size, structure, function or location of the mutation. In all cases, there is an apparen... | ['Huntington Disease', 'Myoglobin', 'Peptides', 'Protein Folding', 'Recombinant Proteins'] | 18,203,800 | [['C10.228.140.079.545', 'C10.228.140.380.278', 'C10.228.662.262.249.750', 'C10.574.500.497', 'C16.320.400.430', 'F03.615.250.400', 'F03.615.400.390'], ['D12.776.210.500.588', 'D12.776.422.316.940'], ['D12.644'], ['G01.154.651', 'G02.111.688'], ['D12.776.828']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protection of reaction center II from photodamage by low temperature and anaerobiosis in spinach chloroplasts. | The rate of the irreversible damage to the reaction center II, caused by exposure of spinach thylakoids to high light was slowed down by anaerobic conditions and by lowering the temperature. The protective mechanisms of these conditions were different. In both cases Fmax decreased more slowly than in control photoinhib... | ['Anaerobiosis', 'Chloroplasts', 'Cold Temperature', 'Light', 'Photochemistry', 'Photosynthetic Reaction Center Complex Proteins', 'Time Factors'] | 2,001,731 | [['G02.111.062', 'G03.078'], ['A11.284.430.214.190.875.700.140'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['H01.181.529.711'], ['D05.500.562.488'... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
An opportunity in op-notes. | Operative notes in surgical practice are a vital source of information and communication between healthcare professionals as well as being a legal document. Errors and omissions can have serious effects on patient care and lead to confusion. We audited our compliance within trauma and orthopaedics at a busy district ge... | ['Nursing Records', 'Surgical Procedures, Operative', 'United Kingdom'] | 26,717,589 | [['E05.318.308.940.984', 'L01.399.250.900.984', 'N04.452.859.675', 'N05.715.360.300.715.550', 'N06.850.520.308.940.984'], ['E04'], ['Z01.542.363']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Benchmarking in health-system pharmacy: current research and practical applications. | The application of benchmarking techniques to hospital pharmacy practice is discussed. Benchmarking is a process designed to discover best practices through a comparison of various competing methods aimed at achieving a particular goal. Benchmarking antimicrobial drug utilization and rates of bacterial resistance throu... | ['Anti-Bacterial Agents', 'Benchmarking', 'Databases as Topic', 'Delivery of Health Care', 'Drug Resistance, Microbial', 'Humans', 'Pharmacy Service, Hospital'] | 11,057,362 | [['D27.505.954.122.085'], ['N04.452.500.150', 'N04.761.685.150', 'N04.761.700.150', 'N05.700.150', 'N05.715.360.650.150'], ['L01.313.500.750.300.188', 'L01.470.750'], ['N04.590.374', 'N05.300'], ['G06.225', 'G07.690.773.984.269'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.216.500.968.603', 'N02.421.668... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: evidence from a phase III randomized trial. | PURPOSE: Expression of ErbB-1 and ErbB-2 (epidermal growth factor receptor and HER2/neu) in breast cancer may cause tamoxifen resistance, but not all studies concur. Additionally, the relationship between ErbB-1 and ErbB-2 expression and response to selective aromatase inhibitors is unknown. A neoadjuvant study for pri... | ['Antineoplastic Agents', 'Breast Neoplasms', 'Disease Progression', 'Double-Blind Method', 'ErbB Receptors', 'Estrogen Antagonists', 'Female', 'Humans', 'Letrozole', 'Logistic Models', 'Neoadjuvant Therapy', 'Nitriles', 'Odds Ratio', 'Postmenopause', 'Receptor, ErbB-2', 'Receptors, Estrogen', 'Receptors, Prostaglandin... | 11,559,718 | [['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['C23.550.291.656'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.543.750.750.400.074'], ['D06.347.295', 'D27.505.696.399.450.327'], ['B01.050.15... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Anti-inflammatory activities of Dictamnus dasycarpus Turcz., root bark on allergic contact dermatitis induced by dinitrofluorobenzene in mice. | ETHNOPHARMACOLOGICAL RELEVANCE: The root bark of Dictamnus dasycarpus Turcz. is widely used as a medicinal herb for treatment of skin diseases such as eczema, pruritus and urticaria in China, Japan and Korea.MATERIALS AND METHODS: We investigated the effects of methanol extract of Dictamnus dasycarpus Turcz., root bark... | ['Animals', 'Anti-Allergic Agents', 'Anti-Inflammatory Agents', 'Cell Proliferation', 'Dermatitis, Allergic Contact', 'Dictamnus', 'Dinitrofluorobenzene', 'Ear', 'Edema', 'Histamine', 'Interferon-gamma', 'Male', 'Methanol', 'Mice', 'Mice, Inbred BALB C', 'Mitogen-Activated Protein Kinases', 'Plant Bark', 'Plant Extract... | 23,850,712 | [['B01.050'], ['D27.505.954.016'], ['D27.505.954.158'], ['G04.161.750', 'G07.345.249.410.750'], ['C17.800.174.255.100', 'C17.800.815.255.100', 'C20.543.418.150'], ['B01.650.940.800.575.912.250.875.255'], ['D02.455.426.559.389.565.280', 'D02.640.529.240.280'], ['A01.456.313', 'A09.246'], ['C23.888.277'], ['D02.092.211.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bilateral renal infarctions complicating fibromuscular dysplasia of renal arteries in a young male. | Fibromuscular dysplasia (FMD) is an uncommon disorder, accounting for less than 10% of cases of renal artery stenosis, and typically presenting with hypertension in young women. This article reports the case of a previously healthy 37-year-old man presenting with acute-onset, severe, bilateral flank pain. Initially tre... | ['Adult', 'Aneurysm, Dissecting', 'Angiography', 'Fibromuscular Dysplasia', 'Follow-Up Studies', 'Humans', 'Infarction', 'Kidney', 'Magnetic Resonance Imaging', 'Male', 'Renal Artery', 'Renal Artery Obstruction', 'Stents', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 21,627,538 | [['M01.060.116'], ['C14.907.055.050'], ['E01.370.350.700.060', 'E01.370.370.050'], ['C14.907.137.372'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.513.355', 'C23.550.717.489'], ['A05.810.453'], ['E01.370.350.825.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Trypsin action on the growth of Sendai virus in tissue culture cells. 3. Structural difference of Sendai viruses grown in eggs and tissue culture cells. | Polypeptides of egg-borne Sendai virus (egg Sendai), which is biologically active on the basis of criteria of the infectivity for L cells and of hemolytic and cell fusion activities, were compared by polyacrylamide gel electrophoresis with those of L cell-borne (L Sendai) and HeLa cell-borne Sendai (HeLa Sendai) viruse... | ['Amino Acids', 'Animals', 'Carbon Radioisotopes', 'Cells, Cultured', 'Chick Embryo', 'Chickens', 'Densitometry', 'Electrophoresis, Polyacrylamide Gel', 'Erythrocytes', 'Glucosamine', 'Glycoproteins', 'HeLa Cells', 'Hemolysis', 'Humans', 'L Cells', 'Mice', 'Parainfluenza Virus 1, Human', 'Peptides', 'Tritium', 'Trypsin... | 4,357,516 | [['D12.125'], ['B01.050'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.196.712.224'], ['E05.196.401.402', 'E05.301.300.319'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D09.067... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Left-handed DNA crossovers. Implications for DNA-DNA recognition and structural alterations. | The close approach of DNA segments participates in many biological functions including DNA condensation and DNA processing. Previous crystallographic studies have shown that B-DNA self-fitting by mutual groove-backbone interaction produces right-handed DNA crossovers. These structures have opened new perspectives on th... | ['Crystallography', 'DNA', 'Models, Molecular', 'Molecular Structure'] | 10,217,449 | [['E05.196.309', 'H01.181.529.240'], ['D13.444.308'], ['E05.599.595'], ['G02.111.570', 'G02.466']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of the next-generation Xpert MRSA/SA BC assay and the GeneOhm StaphSR assay to routine culture for identification of Staphylococcus aureus and methicillin-resistant S. aureus in positive-blood-culture broths. | A bloodstream infection with Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA), is a serious condition that carries a high mortality rate and is also associated with significant hospital costs. The rapid and accurate identification and differentiation of methicillin-susceptible S. aureus (MSSA) an... | ['Adolescent', 'Adult', 'Bacteremia', 'Bacteriological Techniques', 'Blood', 'Child', 'Child, Preschool', 'Humans', 'Infant', 'Methicillin Resistance', 'Molecular Diagnostic Techniques', 'Prospective Studies', 'Sensitivity and Specificity', 'Staphylococcal Infections', 'Staphylococcus aureus'] | 25,540,397 | [['M01.060.057'], ['M01.060.116'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['E01.370.225.875.150', 'E05.200.875.150'], ['A12.207.152', 'A15.145'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G06.099.225.500.600.525', 'G06.225.347.500.6... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis and application of 13C enriched phenylisothiocyanate as a 13C NMR protein probe. | Phenylisothiocyanate, enriched with 13C at the isothiocyanate carbon, has been synthesized and utilized as a 13C NMR probe of proteins for the first time. The reagent has been used to label the amino groups of oxidized glutathione, and the resulting 13C NMR spectrum shows a prominent thiocarbonyl peak after a single NM... | ['Carbon Isotopes', 'Chemical Phenomena', 'Chemistry', 'Glutathione', 'Insulin', 'Isothiocyanates', 'Magnetic Resonance Spectroscopy', 'Protein Denaturation', 'Proteins', 'Thiocyanates'] | 3,548,714 | [['D01.268.150.075', 'D01.496.123'], ['G02'], ['H01.181'], ['D12.644.456.448'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D02.500.375', 'D02.886.250'], ['E05.196.867.519'], ['G01.154.651.750.500', 'G02.111.688.750.500'], ['D12.776'], ['D02.262.775', 'D02.886.728']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Alternative formulations of sorafenib for use in children. | BACKGROUND: Sorafenib is an oral multikinase inhibitor with antiangiogenic and antitumor activity. In most cases, the commercially available 200 mg tablet is not suitable for administration to children. We studied the chemical and physical stability of extemporaneously prepared formulations and evaluated the pharmacoki... | ['Administration, Oral', 'Adolescent', 'Adult', 'Antineoplastic Agents', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Neoplasms', 'Niacinamide', 'Phenylurea Compounds', 'Sorafenib'] | 23,788,485 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['D27.505.954.248'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04'], ['D03.066.515.530', 'D03.383.725.547.530'], ['D02.065.950.681', 'D02.455.426.559.389.703'], ['D02.065.950.681.757', 'D02.455.426.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Does level of care, sex, age, or choice of drug influence adherence to treatment with antipsychotics? | Rates of nonadherence during treatment with antipsychotics have been found to vary in a wide range from 20% to 90%. The aim of the present study was to investigate the influence of inpatient versus outpatient status on the adherence to treatment with olanzapine and clozapine. In the period from 1999 to 2007, olanzapine... | ['Adult', 'Age Factors', 'Ambulatory Care', 'Antipsychotic Agents', 'Choice Behavior', 'Drug Monitoring', 'Female', 'Hospitalization', 'Humans', 'Male', 'Middle Aged', 'Patient Care', 'Patient Compliance', 'Sex Factors', 'Treatment Outcome'] | 19,745,639 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E02.760.106', 'N02.421.585.106'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['F02.463.785.373.346'], ['E01.370.520.200'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M0... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Assessment of drinking water quality at the tap using fluorescence spectroscopy. | Treated drinking water may become contaminated while travelling in the distribution system on the way to consumers. Elevated dissolved organic matter (DOM) at the tap relative to the water leaving the treatment plant is a potential indicator of contamination, and can be measured sensitively, inexpensively and potential... | ['Copper', 'Drinking Water', 'Fluorescence', 'Humic Substances', 'Sewage', 'Soil', 'Spectrometry, Fluorescence', 'Water Microbiology', 'Water Pollutants, Chemical', 'Water Quality'] | 28,822,814 | [['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D01.045.250.875.300', 'D01.248.497.158.459.650.300', 'D01.650.550.925.199', 'G07.203.100.418', 'J02.200.418'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['D02.241.444', 'D02.455.426.559.389.657.377', 'D20.721.500'], ['D20.944.932.500'], ['D20.7... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Integrating sexuality into gynaecological consultations: gynaecologists' perspectives. | There are currently few studies exploring doctors' personal perspectives on integrating sexuality into medical consultations. This study focuses on the views of gynaecologists on introducing, or not introducing, sexuality into their work. A total of 30 semi-structured interviews were conducted with gynaecologists in th... | ['Attitude of Health Personnel', 'Female', 'Gynecology', 'Humans', 'Male', 'Physician-Patient Relations', 'Qualitative Research', 'Referral and Consultation', 'Sexuality', 'Switzerland'] | 23,210,486 | [['F01.100.050', 'N05.300.100'], ['H02.403.763.750', 'H02.403.810.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.650.675', 'N05.300.660.625'], ['H01.770.644.241.850'], ['N04.452.758.849'], ['F01.145.802.975', 'G08.686.867'], ['Z01.542.883']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Isolation and partial characterization of macromolecular urinary aggregates containing carcinoembryonic antigen-like activity. | Carcinoembryonic antigen-like substances in the urine of patients with bladder carcinoma and of healthy male subjects occur in a wide range of average molecular sizes. Some of these substances are glycoproteins giving reactions of antigenic identity with carcinoembryonic antigen (CEA) derived from colorectal carcinoma ... | ['Albumins', 'Carcinoembryonic Antigen', 'Chromatography', 'Colonic Neoplasms', 'Electrophoresis, Polyacrylamide Gel', 'Epitopes', 'Glycoproteins', 'Haptoglobins', 'Humans', 'Immune Sera', 'Immunodiffusion', 'Immunoglobulin A', 'Immunoglobulin G', 'Immunoglobulin M', 'Iodine Radioisotopes', 'Macromolecular Substances',... | 4,136,840 | [['D12.776.034'], ['D12.776.395.550.200.210', 'D12.776.543.550.200.210', 'D23.050.285.329', 'D23.050.301.350.210', 'D23.101.140.300'], ['E05.196.181'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['E05.196.401.402', 'E05.30... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinically Relevant Levels of 4-Aminopyridine Strengthen Physiological Responses in Intact Motor Circuits in Rats, Especially After Pyramidal Tract Injury. | BACKGROUND: 4-Aminopyridine (4-AP) is a Food and Drug Administration-approved drug to improve motor function in people with multiple sclerosis. Preliminary results suggest the drug may act on intact neural circuits and not just on demyelinated ones.OBJECTIVE: To determine if 4-AP at clinically relevant levels alters th... | ['4-Aminopyridine', 'Animals', 'Central Nervous System Agents', 'Cervical Cord', 'Drug Evaluation, Preclinical', 'Electric Stimulation', 'Electromyography', 'Evoked Potentials, Motor', 'Female', 'Forelimb', 'Microelectrodes', 'Motor Cortex', 'Muscle, Skeletal', 'Pyramidal Tracts', 'Random Allocation', 'Rats, Sprague-Da... | 28,107,804 | [['D02.092.080.060', 'D03.383.725.050.060'], ['B01.050'], ['D27.505.954.427'], ['A08.186.854.126'], ['E05.290.750', 'E05.337.550'], ['E05.723.402'], ['E01.370.405.255', 'E01.370.530.255'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['A13.395'], ['E07.305.250.500'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Guanine nucleotides stimulate carboxyl methylation of kidney cytosolic proteins. | We studied the effect of guanine nucleotides on the carboxyl methylation catalyzed by class II protein carboxylmethyltransferases (PCMT). Addition of guanosine 5'-O-(gamma-thio)triphosphate (GTP gamma S) promoted a time- and concentration-dependent enhancement of protein methylation in the cytosolic fraction isolated f... | ['Animals', 'Cytosol', 'Guanine Nucleotides', "Guanosine 5'-O-(3-Thiotriphosphate)", 'Kidney Cortex', 'Kinetics', 'Male', 'Methylation', 'Organ Specificity', 'Protein O-Methyltransferase', 'Rats', 'Rats, Inbred Strains', 'S-Adenosylmethionine', 'Solubility'] | 1,504,099 | [['B01.050'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['D03.633.100.759.646.454', 'D13.695.667.454', 'D13.695.827.426'], ['D02.886.765.380', 'D13.695.667.454.504.380', 'D13.695.827.426.504.380', 'D13.695.900.380'], ['A05.810.453.324'], ['G01.374.661', 'G02.111.490'], ['G02.111.035.538', '... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prophylactic effects of duloxetine on post-stroke depression symptoms: an open single-blind trial. | Post-stroke depression (PSD) is a common yet severe sequela of stroke, and is often accompanied with somatic symptoms. Duloxetine, a new serotonin-norepinephrine reuptake inhibitor, may help to prevent depression after stroke. 95 ischemic stroke patients without depression were randomly divided into two groups: duloxet... | ['Aged', 'Antidepressive Agents', 'Depression', 'Duloxetine Hydrochloride', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neuropsychological Tests', 'Single-Blind Method', 'Stroke', 'Thiophenes'] | 23,549,225 | [['M01.060.116.100'], ['D27.505.954.427.700.122'], ['F01.145.126.350'], ['D02.886.778.260', 'D03.383.903.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F04.711.513'], ['E05.318.370.850', 'N05.715.360.325.730', 'N06.850.520.445.850'], ['C10.228.140.300.775', 'C14.907.253.855'], ['D02.886.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Development of an on-chip injector for microchip-based flow analyses using laminar flow. | A new on-chip injector for microchip-based flow analyses has been designed and characterized. The microchip design utilizes separate laminar flow streams of buffer and sample that are brought into parallel contact for a distance of 300 microm. The buffer flow stream is first routed through a conventional 6-port injecti... | ['Animals', 'Dose-Response Relationship, Drug', 'Electrochemistry', 'Erythrocytes', 'Microfluidics', 'Microscopy, Fluorescence', 'Miniaturization', 'Rabbits'] | 17,960,290 | [['B01.050'], ['G07.690.773.875', 'G07.690.936.500'], ['H01.181.529.307'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['E05.830.666', 'H01.671.808.500', 'J01.897.520.500.500'], ['E01.370.350.515.458', 'E05.595.458'], ['J01.897.520'], ['B01.050.150.900.649.313.968.700']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Effect of norethisterone and levonorgestrel in low-dose multiphasic oral contraceptives on serum lipids. | In a parallel, multicenter study in Norway and Finland involving a total of 196 healthy women (mean age 22.4 years, range 18-30), the effects on serum lipids and lipoproteins of two multiphasic oral contraceptives containing ethinyl estradiol (EE) but different progestins were examined. One formulation contained EE 35 ... | ['Adult', 'Contraceptives, Oral, Combined', 'Ethinyl Estradiol', 'Female', 'Humans', 'Levonorgestrel', 'Lipids', 'Norethindrone', 'Reference Values', 'Single-Blind Method'] | 8,213,103 | [['M01.060.116'], ['D26.310.360', 'D27.505.696.875.360.276.210.100', 'D27.505.954.705.360.276.210.100'], ['D04.210.500.668.651.568.291', 'D06.472.334.851.437.968.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.668.651.693.762.450'], ['D10'], ['D04.210.500.668.651.693.651'], ['E05.978.810'], ['E05.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Serum beta-2-microglobulin, TNF-alpha and interleukins in myeloproliferative disorders. | Whereas beta-2-microglobulin (beta2M) has mainly been used as a prognostic factor in patients with lymphoproliferative disorders, some studies have reported the value of beta2M in myeloproliferative disorders (MPD). In order to investigate a potential role in the pathogenesis of MPD and to find a possible value as indi... | ['Aged', 'Biomarkers, Tumor', 'Disease Progression', 'Female', 'Humans', 'Immunoenzyme Techniques', 'Interleukins', 'Male', 'Middle Aged', 'Myeloproliferative Disorders', 'Tumor Necrosis Factor-alpha', 'beta 2-Microglobulin'] | 10,414,450 | [['M01.060.116.100'], ['D23.101.140'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['D12.644.276.374.465', 'D12.776.467.374.465', 'D23.529.374.465'], ['M01.060.116.630'], ['C15.378.190.636'], ['D12.644.276.374.500.800', 'D12.644.276.37... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Primary study of the use of a shape-memory alloy distraction device in the dog mandible for alveolar ridge distraction: determination of osteotomy techniques and evaluation of osteogenesis outcome. | PURPOSE: The titanium-nickel shape-memory alloy distractor is a new kind of alveolar ridge distraction device that can be completely buried and self-activated. To evaluate this new device, the present study compared the effects of 2 osteotomy techniques and investigated the osteogenesis outcome by measuring the bone mi... | ['Absorptiometry, Photon', 'Alveolar Ridge Augmentation', 'Anatomy, Cross-Sectional', 'Animals', 'Biomechanical Phenomena', 'Bone Density', 'Bone Regeneration', 'Cephalometry', 'Compressive Strength', 'Dental Alloys', 'Dogs', 'Elastic Modulus', 'Equipment Design', 'Internal Fixators', 'Male', 'Mandible', 'Mandibular Os... | 22,632,929 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['E04.545.550.100', 'E06.645.550.100'], ['H01.158.100.185'], ['B01.050'], ['G01.154.090', 'G01.374.089'], ['G11.427.100'], ['G11.427.213.140', 'G16.762.150.150'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['G01.374.180'], ['D25.339.208', 'J01.637... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Iron and porphyria cutanea tarda. | In order to evaluate the pathogenetic role of iron in Porphyria cutanea tarda (PCT), the metabolism of iron was studied in 440 patient with PCT and associated chronic liver disease (CLD) and in 91 nonporphyric CLD patients (used as a control group). The parameters considered were the following: serum iron, ferritin, To... | ['Adolescent', 'Adult', 'Aged', 'Alanine Transaminase', 'Aspartate Aminotransferases', 'Child', 'Child, Preschool', 'Female', 'Ferritins', 'Hepatitis C', 'Hepatitis, Chronic', 'Humans', 'Iron', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Porphyria Cutanea Tarda', 'Transferrin'] | 9,074,791 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D08.811.913.477.700.100'], ['D08.811.913.477.700.225'], ['M01.060.406'], ['M01.060.406.448'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['C06.552.380.350'], ['B01.050.150... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Isolation and characterization of the novel lipophilic protein, Pb CP-12.7, from the shell of the pink shrimp, Pandalus borealis. | Past research on diapause-inducing substances of the silkworm has isolated an extremely lipophilic peptide and demonstrated its unique characteristics. In the present work, similar lipophilic proteins were searched for in the shell of the shrimp, Pandalus borealis, and one novel protein, Pb CP-12.7, was isolated. Its s... | ['Adsorption', 'Amino Acid Sequence', 'Animals', 'Carrier Proteins', 'Chitin', 'Chromatography, High Pressure Liquid', 'Chymotrypsin', 'Molecular Sequence Data', 'Pandalidae', 'Peptide Mapping', 'Protein Conformation'] | 11,440,115 | [['G01.030', 'G02.020'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.157'], ['D05.750.078.139', 'D09.698.211'], ['E05.196.181.400.300'], ['D08.811.277.656.300.760.176', 'D08.811.277.656.959.350.176'], ['L01.453.245.667'], ['B01.050.500.131.365.190.635'], ['E05.196.181.400.454.720', 'E05.196.401.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Audiogenic seizures in rats: relation to noradrenergic neurons of the locus coeruleus. | Bilateral lesions involving the nucleus locus coeruleus produced a substantial decrease in the forebrain noradrenaline concentrations. Lesioned animals showed an increased susceptibility to audiogenic seizures. It is supposed that noradrenergic neurons, belonging to the locus coeruleus, play an inhibitory role in the s... | ['Animals', 'Brain Chemistry', 'Dopamine', 'Locus Coeruleus', 'Male', 'Norepinephrine', 'Rats', 'Seizures', 'Serotonin', 'Sound'] | 747,102 | [['B01.050'], ['G02.111.150', 'G03.185'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['A08.186.211.132.659.473', 'A08.186.211.132.810.428.600.650.437'], ['D02.033.100.291.502', 'D02.092.063.480', 'D02.092.211.215.746', 'D02.092.311.830', 'D02.455.426.559.389.657.166.175.830'], ['... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of a phenolic and a 0.2% chlorhexidine mouthwash on the development of plaque and gingivitis. | Chlorhexidine and phenolic mouthrinses have attracted considerable interest as adjuncts to oral hygiene. The aim of this study was to compare two well known proprietary mouthrinse products for their effects on plaque regrowth, the development of gingivitis and the formation of toothstaining. The study was a single-blin... | ['Adult', 'Analysis of Variance', 'Chlorhexidine', 'Dental Plaque', 'Dental Plaque Index', 'Female', 'Gingivitis', 'Humans', 'Male', 'Mouthwashes', 'Periodontal Index', 'Phenols', 'Single-Blind Method'] | 1,884,574 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D02.078.370.141.100'], ['C07.793.208.377'], ['E05.318.308.980.438.300.300', 'E06.208.250', 'N05.715.360.300.800.438.300.325', 'N06.850.520.308.980.438.300.300', 'N06.890.160.090'], ['C01.408', 'C07.465.714.258.480'], ['B01.050.150.90... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Exosomal CCL2 from Tubular Epithelial Cells Is Critical for Albumin-Induced Tubulointerstitial Inflammation. | Albuminuria is a key instigator of tubulointerstitial inflammation associated with CKD, but the mechanism through which filtered albumin propagates renal injury remains unclear. In this study, we explored the role in this process of exosome mRNA released from tubular epithelial cells (TECs). Compared with control mice,... | ['Acute Kidney Injury', 'Adult', 'Animals', 'Cell Movement', 'Cells, Cultured', 'Chemokine CCL2', 'Disease Models, Animal', 'Epithelial Cells', 'Exosomes', 'Female', 'Gene Silencing', 'Glomerulonephritis, IGA', 'Humans', 'Kidney Tubules', 'Macrophages', 'Male', 'Mice', 'Middle Aged', 'Nephritis', 'Proteinuria', 'RNA, M... | 29,295,871 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116'], ['B01.050'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['D12.644.276.374.200.110.990.600', 'D12.776.467.374.200.110.990.600', 'D23.125.300.110.990.600', 'D23.469.200.110.990.600', 'D23.529.374.200.110.990.500'], ['C22.232', 'E05.598.500', 'E05.599... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Positive effect of dietary soy in ESRD patients with systemic inflammation--correlation between blood levels of the soy isoflavones and the acute-phase reactants. | BACKGROUND: Inflammation is commonly associated with malnutrition and cardiovascular disease in end-stage renal failure patients. Anti-inflammatory properties of the isoflavones, a micronutrient component of soy, have been reported in several experimental models and disease conditions, but never in renal failure. We hy... | ['Acute-Phase Proteins', 'Beverages', 'Biomarkers', 'C-Reactive Protein', 'Dairy Products', 'Diabetic Nephropathies', 'Dietary Proteins', 'Dietary Supplements', 'Double-Blind Method', 'Energy Intake', 'Female', 'Food, Formulated', 'Humans', 'Inflammation', 'Insulin-Like Growth Factor I', 'Interleukin-6', 'Isoflavones',... | 16,766,544 | [['D12.776.124.050'], ['G07.203.100', 'J02.200'], ['D23.101'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['G07.203.300.350', 'J02.500.350'], ['C12.777.419.192', 'C13.351.968.419.192', 'C19.246.099.875'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['G07.203.300.456', 'J02.500.456'], ['E0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Development of a Heat-Inducible Gene Expression System Using Female Gametophytes of Arabidopsis thaliana. | Female gametophyte (FG) is crucial for reproduction in flowering plants. Arabidopsis thaliana produces Polygonum-type FGs, which consist of an egg cell, two synergid cells, three antipodal cells and a central cell. Egg cell and central cell are the two female gametes that give rise to the embryo and surrounding endospe... | ['Arabidopsis', 'Arabidopsis Proteins', 'Gene Expression Regulation, Plant', 'Ovule'] | 31,359,050 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G05.308.375'], ['A18.024.249.500.249.249']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Profile and specialization of the chief of emergency medical services]. | The specific task of emergency medicine consists of the limitation of mortality and morbidity caused by the repercussion on vital system functioning of acute illness and trauma. This task has to be realized within a structure including the mobile emergency care system and the emergency department. The chief of such a s... | ['Curriculum', 'Education, Medical, Continuing', 'Emergency Medicine', 'Emergency Service, Hospital', 'Humans', 'Medical Staff, Hospital', 'Physicians', 'Workforce'] | 3,739,516 | [['I02.158'], ['I02.358.212.350', 'I02.358.399.250'], ['H02.403.250'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.630.490', 'M01.526.485.740.422', 'N02.360.630.490', 'N02.360.740.422'], ['M01.526.485.810', 'N02.360.810'], ['N... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
The Vav binding site (Y315) in ZAP-70 is critical for antigen receptor-mediated signal transduction. | Stimulation of antigen receptors in T and B cells leads to the activation of the Src and Syk families of protein tyrosine kinases (PTK). These PTKs subsequently phosphorylate numerous intracellular substrates, including the 95-kD protooncogene product Vav. Vav is essential for both T and B cell development and T and B ... | ['Adaptor Proteins, Signal Transducing', 'Animals', 'B-Lymphocytes', 'Binding Sites', 'Cell Cycle Proteins', 'Cell Line', 'Glutathione Transferase', 'Humans', 'Kinetics', 'Luciferases', 'Mammals', 'Mutagenesis, Site-Directed', 'Oligopeptides', 'Peptide Biosynthesis', 'Peptides', 'Phosphoproteins', 'Protein-Tyrosine Kin... | 9,151,714 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G02.111.570.120'], ['D12.776.167'], ['A11.251.210'], ['D08.811.913.225.500'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
OCT angiography features of paracentral acute middle maculopathy. | Paracentral acute middle maculopathy (PAMM) refers to retinal lesions with changes in the inner nuclear layer on spectral domain optical coherence tomography (OCT). PAMM is associated with retinal vascular pathology involving the deep capillary plexus. We report two cases of PAMM in Indian subjects using multimodal ima... | ['Acute Disease', 'Adult', 'Capillaries', 'Female', 'Fluorescein Angiography', 'Fundus Oculi', 'Humans', 'Male', 'Optic Disk', 'Retinal Diseases', 'Retinal Vessels', 'Scotoma', 'Tomography, Optical Coherence', 'Visual Acuity'] | 30,777,975 | [['C23.550.291.125'], ['M01.060.116'], ['A07.015.461.165'], ['E01.370.370.050.350', 'E01.370.380.250'], ['A09.371.729.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800.120.680.660', 'A09.371.729.690'], ['C11.768'], ['A07.015.611'], ['C10.597.751.941.811', 'C11.966.811', 'C23.888.592.763.941.811'], [... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genome-wide gene expression profiling, genotyping, and copy number analyses of acute myeloid leukemia using Affymetrix GeneChips. | With novel genome-wide technologies it is nowadays possible to perform detailed molecular analyses of normal and malignant tissues. Acute myeloid leukemia (AML) is a heterogeneous group of diseases with variable response to therapy. Gene expression profiling and genome-wide genotyping have recently been successfully ap... | ['DNA Copy Number Variations', 'Gene Expression Profiling', 'Gene Expression Regulation, Leukemic', 'Genome, Human', 'Genotyping Techniques', 'Humans', 'Leukemia, Myeloid, Acute', 'Mutation', 'Oligonucleotide Array Sequence Analysis'] | 23,824,855 | [['G05.365.795.297.500'], ['E05.393.332'], ['G05.308.370.500'], ['G05.360.340.350'], ['E05.393.442'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.275'], ['G05.365.590'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analyzing weight loss intervention studies with missing data: which methods should be used? | OBJECTIVE: Missing data due to study dropout is common in weight loss trials and several statistical methods exist to account for it. The aim of this study was to identify methods in the literature and to compare the effects of methods of analysis using simulated data sets.METHODS: Literature was obtained for a 1-y per... | ['Clinical Trials as Topic', 'Computer Simulation', 'Data Collection', 'Databases, Factual', 'Humans', 'Models, Statistical', 'Patient Dropouts', 'Probability', 'Research Design', 'Treatment Outcome', 'Weight Loss'] | 23,644,010 | [['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['L01.224.160'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Can Community Health Center funding enhance health services for Native American tribes and organizations? | This paper reports on the applicability of the Public Health Service Act (42 USC, 254b) Section 330 Community Health Center program to Arizona Native American tribes and organizations. Data review and analysis consisted of a review of two federal government documents concerning the funding of Community Health Center ap... | ['Administrative Personnel', 'Arizona', 'Community Health Centers', 'Financing, Government', 'Health Care Surveys', 'Health Knowledge, Attitudes, Practice', 'Health Services, Indigenous', 'Humans', 'Indians, North American', 'Medically Underserved Area', 'Needs Assessment', 'Surveys and Questionnaires', 'United States'... | 15,253,373 | [['M01.526.070'], ['Z01.107.567.875.760.100'], ['N02.278.035.128'], ['N03.219.521.346'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['F01.100.150.500', 'N05.300.150.410'], ['N02.421.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.50... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
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