Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Receptor blockade as a mechanism of deactivation of human neutrophils by pepstatin and formyl-Met-Leu-Phe. | The pentapeptide pepstatin was shown to be chemotactic for human neutrophils by two techniques: ED50 for chemotaxis was found to be 3 microM by the agarose method and 0.2 microM by the Boyden chamber technique. Pepstatin also induced superoxide radical generation, release of lysosomal enzymes, and a transient increase ... | ['Binding, Competitive', 'Chemotaxis', 'Cyclic AMP', 'Cytoplasmic Granules', 'Glucuronidase', 'Humans', 'Muramidase', 'N-Formylmethionine Leucyl-Phenylalanine', 'Neutrophils', 'Oligopeptides', 'Pepstatins', 'Receptors, Immunologic', 'Superoxides'] | 6,325,345 | [['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increasing Rates of Pediatric Empyema and Disease Severity With Predominance of Serotype 3 S. pneumonia: An Australian Single-center, Retrospective Cohort 2011 to 2018. | BACKGROUND: The impact of universal 13-valent pneumococcal conjugate vaccine immunization on pediatric empyema rates and pathogens in Australia is not known. We aimed to describe empyema epidemiology, clinical characteristics and treatment during an 8-year period.METHODS: A retrospective study between 2011 and 2018 of ... | ['Australia', 'Child', 'Child, Preschool', 'Empyema', 'Female', 'Hospitalization', 'Humans', 'Incidence', 'Infant', 'Longitudinal Studies', 'Male', 'Pneumococcal Infections', 'Pneumococcal Vaccines', 'Pneumonia, Bacterial', 'Retrospective Studies', 'Serogroup', 'Severity of Illness Index', 'Staphylococcal Infections', ... | 31,634,299 | [['Z01.639.100', 'Z01.678.100.373'], ['M01.060.406'], ['M01.060.406.448'], ['C01.830.305', 'C23.550.470.756.305'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.... | ['Geographicals [Z]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
T-Cell Prolymphocytic Leukemia, Small Cell Variant, Possibly at the Stage of Intracytoplasmic Expression of CD3 in T-Cell Ontogenesis. | T-cell prolymphocytic leukemia, small cell variant (T-PLL-s), is a rare lymphoid neoplasm associated with a poor prognosis. We encountered a case of T-PLL-s with a characteristic phenotype. A 67-year-old female was referred to our hospital because of lymphocytosis in August 2013. Hepatosplenomegaly, lymphadenopathy, an... | ['Aged', 'Antigens, CD', 'Blood Cell Count', 'Cell Transformation, Neoplastic', 'Female', 'Humans', 'Immunophenotyping', 'Leukemia, Prolymphocytic, T-Cell', 'Neoplasm Staging', 'Receptors, Antigen, T-Cell, alpha-beta', 'T-Lymphocytes'] | 26,106,002 | [['M01.060.116.100'], ['D23.050.301.264.035', 'D23.101.100.110'], ['E01.370.225.500.195.107', 'E01.370.225.625.107', 'E05.200.500.195.107', 'E05.200.625.107', 'E05.242.195.107', 'G04.140.107', 'G09.188.105'], ['C04.697.098.500', 'C23.550.727.098.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Adoption, adoption seeking, and relinquishment for adoption in the United States. | OBJECTIVES: This report presents national data on adoption and adoption-related behaviors among ever-married women 18-44 years of age in the United States, according to selected characteristics of the women. Trends are shown in the prevalence of adoption and relinquishment of children for adoption. For 1995, the report... | ['Adolescent', 'Adoption', 'Adult', 'Choice Behavior', 'Consumer Behavior', 'Data Collection', 'Ethnic Groups', 'Female', 'Fertility', 'Humans', 'Infertility, Female', 'Marriage', 'National Center for Health Statistics, U.S.', 'Needs Assessment', 'Single Person', 'United States'] | 10,662,357 | [['M01.060.057'], ['I01.880.853.150.140'], ['M01.060.116'], ['F02.463.785.373.346'], ['F01.145.236'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['M01.686.754', 'N01.224.317'], ['G08.686.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['F01.829.263.315.500.500... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
New data on the morphology of species of Leptotaenia Cohn, 1901 (Cestoda: Progynotaeniidae). | Leptotaenia ischnorhyncha (L?he, 1898) is redescribed on the basis of a specimen from Phoenicopterus ruber in Cuba. In contrast to previous descriptions, the presence of two rows of rostellar hooks, a secondary female copulatory organ and four types of cirrus spines are observed. Leptotaenia sp. from P. minor from Keny... | ['Animals', 'Cuba', 'Female', 'Male', 'Taenia'] | 15,084,829 | [['B01.050'], ['Z01.107.084.900.225', 'Z01.639.880.225'], ['B01.050.500.500.736.215.895']] | ['Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Granulomatous hepatitis following open heart surgery with cardiopulmonary bypass. | BACKGROUND: Cardiopulmonary bypass (CPB) initiates an inflammatory cascade, predisposing the patient to a number of infections. The stress of surgery and anaesthesia further expose the patient to a variety of non-infectious complications. We report a group of patients who developed granulomatous disease after open hear... | ['Adult', 'Cardiopulmonary Bypass', 'Case-Control Studies', 'Female', 'Fever', 'Granuloma', 'Hepatitis', 'Hepatomegaly', 'Humans', 'Inflammation', 'Jaundice', 'Male', 'Retrospective Studies', 'Time Factors'] | 19,320,320 | [['M01.060.116'], ['E04.292.413'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.888.119.344'], ['C15.604.515.292', 'C23.550.382'], ['C06.552.380'], ['C06.552.416', 'C23.300.775.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['C23.550.429.500', 'C23.888.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Immunologic defense in bacterial and viral meningitis in children. | The investigation of a number of parameters of nonspecific and specific defense in 13 purulent and 18 mumps meningitides gave no indication of underlying primary immunodeficiencies. Only in the acute phase of mumps meningitis did we find a temporary suppression of cellular immune reactions measured as diminished rate o... | ['Humans', 'Immunity, Cellular', 'Infant', 'Lectins', 'Lymphocytes', 'Meningitis', 'Meningitis, Haemophilus', 'Meningitis, Meningococcal', 'Meningitis, Pneumococcal', 'Meningitis, Viral', 'Mumps', 'Thymidine', 'Time Factors'] | 1,001,323 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.050.400'], ['M01.060.703'], ['D12.776.503'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['C10.228.614'], ['C01.150.252.223.500.425', 'C01.150.252.400.700.433.615', 'C01.207.180.500.425', 'C10.228.228.180.500.425', 'C10.228.614.2... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Intraperitoneal contrast material improves the CT detection of peritoneal metastases. | The preoperative detection of peritoneal metastases from gynecologic malignancies is difficult; in particular, CT often fails to detect peritoneal implants. This study was designed to determine if the administration of intraperitoneal iodinated contrast media would increase the CT detection of such peritoneal metastase... | ['Diatrizoate Meglumine', 'Evaluation Studies as Topic', 'Female', 'Humans', 'Infusions, Parenteral', 'Ovarian Neoplasms', 'Peritoneal Neoplasms', 'Prospective Studies', 'Sensitivity and Specificity', 'Tomography, X-Ray Computed'] | 2,048,534 | [['D02.033.800.813.550.500', 'D02.241.223.100.400.880.270.500', 'D02.455.426.559.389.127.375.880.270.500', 'D09.067.342.600.500', 'D09.853.813.550.500'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.510'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Calculation of NMR relaxation, covolume, and scattering-related properties of bead models using the SOLPRO computer program. | The hydrodynamic properties of macromolecules and bioparticles, represented by bead models, can be calculated using methods implemented in the computer routine HYDRO. Recently, a new computer routine, SOLPRO, has been presented for the calculation of various SOLution PROperties. These include (1) time-dependent electro... | ['Mathematical Computing', 'Models, Molecular', 'Monte Carlo Method', 'Nuclear Magnetic Resonance, Biomolecular', 'Scattering, Radiation', 'Software', 'Solutions', 'X-Rays'] | 10,028,237 | [['L01.224.680'], ['E05.599.595'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['E05.196.867.519.550'], ['E05.196.822', 'G01.867'], ['L01.224.900'], ['D26.776'], ['G01.358.500.505.970', 'G01.750.250.970', 'G01.750.750.918']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Pro-tobacco advertisement exposure among African American smokers: An ecological momentary assessment study. | INTRODUCTION: Many African Americans live in communities with a disproportionately high density of tobacco advertisements compared to Whites. Some research indicates that point-of-sale advertising is associated with impulse purchases of cigarettes and smoking. Ecological Momentary Assessment (EMA) can be used to examin... | ['Adolescent', 'Adult', 'Advertising', 'African Americans', 'Aged', 'District of Columbia', 'Ecological Momentary Assessment', 'Female', 'Humans', 'Male', 'Middle Aged', 'Smokers', 'Smoking', 'Tobacco Products', 'Young Adult'] | 29,174,665 | [['M01.060.057'], ['M01.060.116'], ['J01.219.687.274', 'L01.143.050'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['Z01.107.567.875.500.210', 'Z01.433.429'], ['F04.711.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.808'], ['F01.145.805'], ['J01.637.767.844'], ['... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 |
Dietary vitamin D3 supplementation at 10? the adequate intake improves functional capacity in the G93A transgenic mouse model of ALS, a pilot study. | BACKGROUND: Vitamin D has antioxidant, anti-inflammatory, and neuroprotective properties, and may mitigate amyotrophic lateral sclerosis (ALS) pathology.AIMS: To determine the effects of dietary vitamin D(3) (D(3)) at 10-fold the adequate intake (AI) on functional and disease outcomes and lifespan in the transgenic G93... | ['Amyotrophic Lateral Sclerosis', 'Animals', 'Cholecalciferol', 'Dietary Supplements', 'Disease Models, Animal', 'Female', 'Humans', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Pilot Projects', 'Recovery of Function', 'Sex Factors', 'Superoxide Dismutase', 'Up-Regulation'] | 22,591,278 | [['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['B01.050'], ['D04.210.500.247.222.159', 'D04.210.500.247.808.146', 'D04.210.500.812.768.196', 'D10.570.938.146'], ['G07.203.300.456', 'J02.500.456'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.64... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Monitoring honey bee health in five natural protected areas in Italy. | The health status of the honey bee populations has attracted a great amount of interest in recent years. We investigated honey bee health in five natural protected areas in Italy from October 2009 to December 2010. Areas were selected to represent a wide range of bio‑geographical zones including alpine, continental, an... | ['Animals', 'Beekeeping', 'Bees', 'Italy', 'Parks, Recreational'] | 30,843,178 | [['B01.050'], ['J01.040.207'], ['B01.050.500.131.617.720.500.500.875.387'], ['Z01.542.489'], ['J03.925.680']] | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Nemo-like kinase (NLK) negatively regulates NF-kappa B activity through disrupting the interaction of TAK1 with IKKâ. | Stringent negative regulation of the transcription factor NF-êB is essential for maintaining cellular stress responses and homeostasis. However, the tight regulation mechanisms of IKKâ are still not clear. Here, we reported that nemo-like kinase (NLK) is a suppressor of tumor necrosis factor (TNFá)-induced NF-êB signal... | ['Cell Nucleus', 'Gene Expression Regulation', 'HCT116 Cells', 'HEK293 Cells', 'Humans', 'I-kappa B Kinase', 'Intracellular Signaling Peptides and Proteins', 'MAP Kinase Kinase Kinases', 'NF-kappa B', 'Phosphorylation', 'Protein Binding', 'Protein-Serine-Threonine Kinases', 'Proteolysis', 'RNA, Small Interfering', 'Sig... | 24,721,172 | [['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G05.308'], ['A11.251.210.190.380', 'A11.251.860.180.380'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.494', 'D12.644.360.361', 'D12.776.476.378'], ['D12.644.360', 'D12.776.476'], ['D08.811.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Post-kala-azar dermal leishmaniasis: a case report strikingly resembling lepromatous leprosy. | An adult man with post-kala-azar dermal leishmaniasis who had lessons distributed in a manner strikingly similar to lepromatous leprosy is described. He was mistakenly treated with multidrug therapy as recommended by the WHO Expert Committee on leprosy. All investigations including slit-skin smears, histopathology, cul... | ['Animals', 'Antimony Sodium Gluconate', 'Diagnostic Errors', 'Humans', 'Leishmaniasis, Visceral', 'Leprosy, Lepromatous', 'Male', 'Middle Aged', 'Skin'] | 1,651,437 | [['B01.050'], ['D02.125', 'D02.241.081.844.322.060', 'D02.241.511.902.322.060', 'D09.811.308.060'], ['E01.354', 'N02.421.450.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.610.752.300.500.510', 'C01.920.813.510'], ['C01.150.252.410.040.552.475.371.775.500'], ['M01.060.116.630'], ['A17.815']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enhanced chemopreventive effects of a hydrogen sulfide-releasing anti-inflammatory drug (ATB-346) in experimental colorectal cancer. | Regular use of nonsteroidal anti-inflammatory drugs is associated with a significantly lower incidence of several types of cancer, particularly those affecting the gastrointestinal tract. However, the propensity of these drugs to cause ulcers and bleeding in the stomach and small intestine limits their utility for chem... | ['Aberrant Crypt Foci', 'Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Azoxymethane', 'Colon', 'Colorectal Neoplasms', 'Dinoprostone', 'Male', 'Mice', 'Naproxen', 'Protective Agents', 'Rats', 'Thromboxane B2'] | 24,747,869 | [['C04.834.020'], ['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D02.172.080'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Psychosocial correlates of cigarette smoking among college students in China. | The objectives are to examine the smoking practice and intention among Chinese college students and to explore the association between cigarette smoking and individual and psychosocial factors. Cross-sectional data were collected from 1874 students from 19 college campuses in Jiangsu province, China. Both bivariate and... | ['Adult', 'Age Factors', 'China', 'Cross-Sectional Studies', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Intention', 'Male', 'Peer Group', 'Self Efficacy', 'Sex Factors', 'Smoking', 'Social Isolation', 'Socioeconomic Factors', 'Students', 'Universities'] | 18,281,711 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['Z01.252.474.164'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.650', 'F02.463.306'], ['F01.829.316.483'], ['F01.752.747.792.70... | ['Named Groups [M]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Effect of taurine-conjugated ursodeoxycholic acid on endoplasmic reticulum stress and apoptosis induced by advanced glycation end products in cultured mouse podocytes. | BACKGROUND: Activations of death receptors and mitochondrial damage are well-described common apoptotic pathways. Recently, a novel pathway via endoplasmic reticulum (ER) stress has been reported.METHODS: We assessed the role of tauroursodeoxycholic acid (TUDCA) in inhibition of ER stress and its protective effect on a... | ['Animals', 'Apoptosis', 'Calcium', 'Endoplasmic Reticulum', 'Gene Expression Regulation', 'Glycation End Products, Advanced', 'Heat-Shock Proteins', 'Mice', 'Microscopy, Confocal', 'Models, Biological', 'Molecular Chaperones', 'Podocytes', 'Taurine', 'Taurochenodeoxycholic Acid', 'Time Factors', 'Ursodeoxycholic Acid'... | 18,648,192 | [['B01.050'], ['G04.146.954.035'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.284.430.214.190.875.248'], ['G05.308'], ['D12.776.643.500'], ['D12.776.580.216'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.515.395', 'E05.595.395'], ['E05.599.395'], ['D12.776.580'], ['A05.810.453.324.359.3... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mineral dust aerosols promote the formation of toxic nitropolycyclic aromatic compounds. | Atmospheric nitrated polycyclic aromatic hydrocarbons (NPAHs), which have been shown to have adverse health effects such as carcinogenicity, are formed in part through nitration reactions of their parent polycyclic aromatic hydrocarbons (PAHs) in the atmosphere. However, little is known about heterogeneous nitration ra... | ['Aerosols', 'Air Pollutants', 'Beijing', 'Chemical Phenomena', 'Dust', 'Kinetics', 'Minerals', 'Nitro Compounds', 'Polycyclic Aromatic Hydrocarbons', 'Spectroscopy, Fourier Transform Infrared', 'Surface Properties'] | 27,075,250 | [['D20.280.055', 'D26.255.165.055'], ['D27.888.284.101'], ['Z01.252.474.164.225', 'Z01.433.114'], ['G02'], ['D20.633.222'], ['G01.374.661', 'G02.111.490'], ['D01.578'], ['D02.640'], ['D02.455.426.559.847', 'D04.615'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['G02.860']] | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Effect of storage time on clinical efficacy of single-donor platelet units. | Decrements in platelet function and recovery are known to accumulate during the 5-day storage period, and the clinical response to platelets transfused after several days' storage has been suggested by some researchers to be less than that seen with platelets stored for shorter periods. The clinical response to single-... | ['Blood Donors', 'Blood Platelets', 'Blood Preservation', 'Blood Transfusion', 'Bone Marrow Transplantation', 'Cell Survival', 'Humans', 'Platelet Count', 'Time Factors'] | 8,342,233 | [['M01.898.313'], ['A11.118.188', 'A15.145.229.188'], ['E02.792.833.230', 'E05.760.833.230'], ['E02.095.135'], ['E02.095.147.725.040', 'E04.936.580.040'], ['G04.346'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.195.107.740', 'E01.370.225.625.107.700', 'E01.370.225.625.625.625', 'E05.200.500.195.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Homocystinuria and schizophrenia. Literature review and case report. | The autosomal recessive disorder homocystinuria involves, in all its subgroups, an abnormality of methionine metabolism. The metabolism of methionine has been a central focus of interest for those who propose the transmethylation hypothesis of schizophrenia. The "methionine effect," as described in the research literat... | ['Adult', 'Animals', 'Chronic Disease', 'Female', 'Homocystinuria', 'Humans', 'Intellectual Disability', 'Male', 'Methionine', 'Mice', 'Rats', 'Schizophrenia'] | 3,965,612 | [['M01.060.116'], ['B01.050'], ['C23.550.291.500'], ['C10.228.140.163.100.365', 'C16.320.565.100.480.500', 'C16.320.565.189.365', 'C17.300.428', 'C18.452.132.100.365', 'C18.452.648.100.480.500', 'C18.452.648.189.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A study of the workforce in emergency medicine: 2007. | INTRODUCTION: This study was undertaken to describe the current status of the emergency medicine workforce in the United States.METHODS: Surveys were distributed in 2008 to 2619 emergency department (ED) medical directors and nurse managers in hospitals in the 2006 American Hospital Association database.RESULTS: Among ... | ['Certification', 'Emergency Medicine', 'Emergency Service, Hospital', 'Humans', 'Nurses', 'United States', 'Workforce'] | 19,751,626 | [['N03.706.110.120', 'N05.700.200.190'], ['H02.403.250'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.650', 'N02.360.650'], ['Z01.107.567.875'], ['N04.452.525']] | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Proteomic expression profiling of Haemophilus influenzae grown in pooled human sputum from adults with chronic obstructive pulmonary disease reveal antioxidant and stress responses. | BACKGROUND: Nontypeable Haemophilus influenzae colonizes and infects the airways of adults with chronic obstructive pulmonary disease, the fourth most common cause of death worldwide.Thus, H. influenzae, an exclusively human pathogen, has adapted to survive in the hostile environment of the human airways.To characteriz... | ['Adult', 'Antioxidants', 'Bacterial Proteins', 'Chromatography, Liquid', 'Haemophilus influenzae', 'Humans', 'Mass Spectrometry', 'Proteome', 'Pulmonary Disease, Chronic Obstructive', 'Sputum', 'Stress, Physiological'] | 20,515,494 | [['M01.060.116'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D12.776.097'], ['E05.196.181.400'], ['B03.440.450.600.450.330', 'B03.660.250.550.290.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.566'], ['D12.776.817'], ['C08.381.495.389'], ['A12.200.808'], ['G07.775']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Autograft versus allograft: an economic cost comparison of anterior cruciate ligament reconstruction. | PURPOSE: The purpose of this study was to compare the costs associated with anterior cruciate ligament (ACL) reconstruction with either bone-patellar tendon-bone (BPTB) autograft or BPTB allograft.METHODS: Surgical costs are reported, including supply costs, based on invoice costs per item used per procedure, and perso... | ['Adolescent', 'Adult', 'Ambulatory Surgical Procedures', 'Anterior Cruciate Ligament', 'Anterior Cruciate Ligament Injuries', 'Anterior Cruciate Ligament Reconstruction', 'Arthroscopy', 'Bone-Patellar Tendon-Bone Grafting', 'Costs and Cost Analysis', 'Female', 'Humans', 'Male', 'Menisci, Tibial', 'Middle Aged', 'Minne... | 21,820,267 | [['M01.060.057'], ['M01.060.116'], ['E04.030'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['C26.558.554.213'], ['E04.555.110.026', 'E04.680.101.026'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['E02.095.147.725.065', 'E04.555.110.026.500', 'E04.680.101.026.500', 'E04.936.580.06... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Co-administration of aprotinin and epsilon-aminocaproic acid during cardiopulmonary bypass in a swine model. | Despite the beneficial effects of pharmacological interventions to prevent bleeding and to reduce the need for autogeneic blood, there are concerns that these agents induce a prothrombotic state. The purpose of this study was to examine the coagulation phenomena influenced by the coadministration of epsilon-aminocaproi... | ['Aminocaproic Acid', 'Animals', 'Antifibrinolytic Agents', 'Aprotinin', 'Blood Coagulation', 'Cardiopulmonary Bypass', 'Hemostatics', 'Models, Animal', 'Swine', 'United States'] | 11,194,056 | [['D02.241.081.193.150.075', 'D12.125.213.075'], ['B01.050'], ['D27.505.519.421.500', 'D27.505.954.502.270.463.091'], ['D12.776.083'], ['G09.188.390.150'], ['E04.292.413'], ['D27.505.954.502.270.463'], ['E05.598'], ['B01.050.150.900.649.313.500.880'], ['Z01.107.567.875']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Recombinant human follicle-stimulating hormone and transforming growth factor-alpha enhance in vitro maturation of porcine oocytes. | The biological functions of recombinant human follicle-stimulating hormone (FSH) and transforming growth factor-á (TGF-á) on in vitro maturation of porcine oocytes were investigated. Cumulus-oocyte complexes were matured in defined porcine oocyte medium containing 0-0.1 IU/ml FSH in the presence or absence of 10 ng/ml ... | ['Animals', 'Cell Culture Techniques', 'Cumulus Cells', 'DNA Primers', 'Fertilization', 'Follicle Stimulating Hormone', 'Gene Expression Regulation, Developmental', 'Humans', 'Oocytes', 'Recombinant Proteins', 'Reverse Transcriptase Polymerase Chain Reaction', 'Signal Transduction', 'Swine', 'Transforming Growth Factor... | 23,661,505 | [['B01.050'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['A05.360.319.114.630.535.200.500', 'A06.300.312.497.535.300.500', 'A11.382.812.500', 'A11.436.329.500'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G08.686.784.277'], ['D06.472.699.322.576.288', 'D06.472.699.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-resolution fast spin echo imaging of the human brain at 4.7 T: implementation and sequence characteristics. | In this work, a number of important issues associated with fast spin echo (FSE) imaging of the human brain at 4.7 T are addressed. It is shown that FSE enables the acquisition of images with high resolution and good tissue contrast throughout the brain at high field strength. By employing an echo spacing (ES) of 22 ms,... | ['Adult', 'Brain', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male'] | 15,170,847 | [['M01.060.116'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Reversal in the relationship between species richness and turnover in a phytoplankton community. | Negative relationships between species richness and the rate of compositional turnover are common, suggesting that diverse communities have greater stability than depauperate ones; however, the mechanistic basis for this pattern is still widely debated. Species richness and turnover can covary either because they are m... | ['Biodiversity', 'Lakes', 'Phytoplankton', 'Population Dynamics', 'Switzerland', 'Time Factors'] | 23,236,914 | [['G16.500.275.157.049', 'N06.230.124.049'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['B05.080.500.600'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['Z01.542.883'], ['G01.910.857']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Recombinase activating gene expression in thymic subpopulations. A transitional cell type has lost RAG-2 but not RAG-1. | We have used a highly sensitive Northern blot probing technique to examine RAG-1 and RAG-2 mRNA expression in unmanipulated murine thymocytes of various developmental phenotypes sorted by flow cytometry. We have found that neither RAG-1 nor RAG-2 are down-regulated until thymocytes reach the TCRhi stage. TCRhi, CD8+CD4... | ['Animals', 'Base Sequence', 'DNA-Binding Proteins', 'Flow Cytometry', 'Gene Expression', 'Gene Rearrangement, T-Lymphocyte', 'Homeodomain Proteins', 'Mice', 'Mice, Inbred C57BL', 'Molecular Sequence Data', 'Oligodeoxyribonucleotides', 'Proteins', 'RNA, Messenger', 'Receptors, Antigen, T-Cell', 'Recombination, Genetic'... | 8,432,979 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.260'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['G05.297'], ['G05.344.801', 'G12.500.287'], ['D12.776.260.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[The caudal regression syndrome (author's transl)]. | Caudal regression syndrome in a male newborn with total aplasia of the vertebral column below L I is reported. A family history of malformations of the vertebral column and diabetes as atiologic factors are discussed. | ['Abnormalities, Multiple', 'Diabetes Mellitus', 'Heart Defects, Congenital', 'Humans', 'Infant, Newborn', 'Leg', 'Male', 'Penis', 'Spinal Cord', 'Syndrome'] | 574,583 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mycobacterium simiae cervical lymphadenitis. | Mycobacterium simiae, a multidrug-resistant, opportunistic acid-fast bacillus, usually causes infection in immunocompromised hosts. We describe a previously healthy child with M. simiae necrotizing granulomatous cervical lymphadenitis. Cure was achieved with excision of the affected nodes and adjunctive antimicrobial t... | ['Animals', 'Anti-Bacterial Agents', 'Drug Resistance, Multiple, Bacterial', 'Female', 'Humans', 'Infant', 'Lymph Nodes', 'Macaca mulatta', 'Mycobacterium', 'Mycobacterium Infections', 'Radiography', 'Tuberculosis, Lymph Node'] | 17,414,407 | [['B01.050'], ['D27.505.954.122.085'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A10.549.400', 'A15.382.520.604.412'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['B03.510.024.962.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Complete cDNA sequence of a major 3-methylcholanthrene-inducible cytochrome P-450 isozyme (P-450AFB) of Syrian hamsters with high activity toward aflatoxin B1. | Cytochrome P-450AFB is major isozyme inducible by 3-methylcholanthrene in Syrian golden hamsters and shows high potency toward aflatoxin B1 activation. We have isolated and sequenced cDNA clones to P-450AFB by immunoscreening a hamster liver cDNA library in lambda gt11. The longest clone contains an open reading frame ... | ['Aflatoxin B1', 'Aflatoxins', 'Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cloning, Molecular', 'Cricetinae', 'Cytochrome P-450 Enzyme System', 'DNA', 'Genes', 'Isoenzymes', 'Male', 'Mesocricetus', 'Methylcholanthrene', 'Molecular Sequence Data', 'Multigene Family', 'RNA, Messenger', 'Sequence Homology, Nucleic... | 2,502,109 | [['D03.383.663.283.119.075', 'D03.633.100.150.119.075', 'D23.946.587.142.075'], ['D03.383.663.283.119', 'D03.633.100.150.119', 'D23.946.587.142'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['B01.050.150.900.649.313.992.635.075.25... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Sleep and quality of life of patients with glycogen storage disease on standard and modified uncooked cornstarch. | BACKGROUND: Glycemic control in hepatic glycogen storage diseases (GSDs) relies on specific nutritional recommendations, including strict avoidance of a fasting period. Uncooked cornstarch (UCCS) is an important therapeutic component. A new modified UCCS, Glycosade™, was created with the objective of prolonging euglyce... | ['Actigraphy', 'Adult', 'Blood Glucose', 'Fasting', 'Female', 'Glucose', 'Glycogen Storage Disease', 'Humans', 'Hypoglycemia', 'Male', 'Middle Aged', 'Prospective Studies', 'Quality of Life', 'Sleep', 'Starch', 'Treatment Outcome', 'Young Adult'] | 29,223,626 | [['E01.370.520.049', 'E05.003.500'], ['M01.060.116'], ['D09.947.875.359.448.500'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['D09.947.875.359.448'], ['C16.320.565.202.449', 'C18.452.648.202.449'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.984'], ['M01.060.116.630'], ['E05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Polymer-lipid hybrid nanoparticles: A novel drug delivery system for enhancing the activity of Psoralen against breast cancer. | A polymer-lipid hybrid nanocarrier was developed to encapsulate psoralen (PSO) to improve its water solubility and bioavailability. The effects of PSO-loaded polymer-lipid hybrid nanoparticles (PSO-PLNs) on breast cancer MCF-7 cells were investigated. PSO-PLNs were prepared through a nanoprecipitation method and were o... | ['Animals', 'Biological Availability', 'Cell Line, Tumor', 'Doxorubicin', 'Drug Delivery Systems', 'Drug Liberation', 'Ficusin', 'Humans', 'Lipids', 'Mice', 'Nanoparticles', 'Particle Size', 'Polymers', 'Solubility', 'Surface Properties', 'Xenograft Model Antitumor Assays'] | 30,851,393 | [['B01.050'], ['G03.787.151', 'G07.690.725.129'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['E02.319.300'], ['G02.211', 'G03.787.321', 'G07.690.725.321'], ['D03.383.663.283.446.794.200', 'D03.633.100.150.446.794.200', 'D03.633... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Measuring depressive symptomatology in a general population. | Three hundred twenty respondents in selected geographic areas were interviewed with a structured questionnaire that included the Zung Self-Rating Depression Scale. Dimensional analysis indicates that some items are not pure measures of the constructs they were originally intended to assess. Moreover, some of the dimens... | ['Adjustment Disorders', 'Adolescent', 'Adult', 'Aged', 'Aging', 'Cultural Characteristics', 'Depression', 'Female', 'Humans', 'Interview, Psychological', 'Male', 'Middle Aged', 'Psychiatric Status Rating Scales', 'Self Concept', 'United States'] | 1,156,115 | [['F03.950.500'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['I01.076.201.450.324', 'I01.880.853.100.329'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.669.599'], ['M01.060.116.630'], ['F04.711.513.653'], ['F01.752.747.792'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Long-Term Studies Assessing Outcomes of Ibrutinib Therapy in Patients With Del(11q) Chronic Lymphocytic Leukemia. | BACKGROUND: Certain genomic features, such as del(11q), expression of unmutated immunoglobulin heavy-chain variable region (IGHV) gene, or complex karyotype, predict poorer outcomes to chemotherapy in patients with chronic lymphocytic leukemia (CLL).PATIENTS AND METHODS: We examined the pooled long-term follow-up data ... | ['Abnormal Karyotype', 'Antineoplastic Agents', 'Chromosome Deletion', 'Chromosomes, Human, Pair 11', 'Clinical Trials as Topic', 'Female', 'Humans', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Male', 'Prognosis', 'Proportional Hazards Models', 'Protein Kinase Inhibitors', 'Pyrazoles', 'Pyrimidines', 'Treatment Outcome'... | 31,447,270 | [['C23.550.210.024', 'G05.360.162.679.500', 'G05.365.590.175.024'], ['D27.505.954.248'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['A11.284.187.520.300.325.355', 'G05.360.162.520.300.325.355'], ['E05.318.372.2... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Molecular phylogeny of the manakins (Aves: Passeriformes: Pipridae), with a new classification and the description of a new genus. | The phylogenetic relationships within the manakin family (Pipridae) were investigated with sequence data from three nuclear introns and one mitochondrial protein-coding gene. This study confirms a sister group relationship between Neopelminae and Piprinae. We also find support for dividing the Piprinae into two princip... | ['Animals', 'Bayes Theorem', 'Biological Evolution', 'Cell Nucleus', 'Genes, Mitochondrial', 'Introns', 'Likelihood Functions', 'Passeriformes', 'Phylogeny', 'Sequence Analysis, DNA'] | 23,831,559 | [['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['G05.045', 'G16.075'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G05.360.340.024.340.365', 'G05.420.275.500'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'], ['E05.318.740.500.475', 'E05.318.740.600.40... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
The clinical value of computerized axial tomography in patients without focal neurological features. | 74 randomly selected patients with non-focal cerebral symptoms and a normal neurologic examination were referred from neurologic departments to CT scan of the brain. 29 patients had generalised epilepsy of long duration. In 26 patients (90%) with epilepsy the CT scan was normal. 2 patients (7%) had cerebral atrophy, 1 ... | ['Adolescent', 'Adult', 'Aged', 'Brain', 'Brain Diseases', 'Epilepsy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Tomography, X-Ray Computed'] | 4,035,264 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A08.186.211'], ['C10.228.140'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Computer model of excitation and recovery in the anisotropic myocardium. III. Arrhythmogenic conditions in the simplified left ventricle. | A computer model of propagated excitation and recovery in anisotropic cardiac tissue has been described in the first two reports of this series. The model consists of a large number of excitable elements whose subthreshold interactions are governed by the anisotropic bidomain theory but whose suprathreshold behavior (a... | ['Action Potentials', 'Computer Simulation', 'Electric Conductivity', 'Heart Conduction System', 'Heart Ventricles', 'Ischemia', 'Models, Cardiovascular', 'Tachycardia', 'Ventricular Function, Left'] | 2,056,266 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['L01.224.160'], ['G01.358.500.249.277'], ['A07.541.409'], ['A07.541.560'], ['C23.550.513'], ['E05.599.395.161'], ['C14.280.067.845', 'C14.280.123.875', 'C23.550.073.845'], ['G09.330.955.800']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Fusion of the FUS and ATF1 genes in a large, deep-seated angiomatoid fibrous histiocytoma. | We report a case of a large, deep-seated, diagnostically difficult angiomatoid fibrous histiocytoma. The neoplastic cells were positive for vimentin, calponin, CD99, and, focally, for desmin and contained intertwining cytoplasmic processes joined by desmosomelike junctions. Fusion of codon 175 of the gene to codon 110 ... | ['Activating Transcription Factor 1', 'Adult', 'Artificial Gene Fusion', 'Biomarkers, Tumor', 'DNA-Binding Proteins', 'Hemangioma', 'Histiocytoma, Benign Fibrous', 'Humans', 'Male', 'RNA-Binding Protein FUS', 'Reverse Transcriptase Polymerase Chain Reaction', 'Transcription Factors'] | 12,218,455 | [['D12.776.260.108.061.500', 'D12.776.930.127.061.500'], ['M01.060.116'], ['E05.393.220.250'], ['D23.101.140'], ['D12.776.260'], ['C04.557.645.375'], ['C04.557.450.565.590.425.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.725.813.750.905', 'D12.776.624.664.700.915', 'D12.776.664.962.813.750.902'... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Breast augmentation for correction of minor and moderate breast ptosis with anatomic breast implant]. | OBJECTIVE: To evaluate a breast augmentation technique for correction of minor and moderate breast ptosis with an anatomic implant.METHODS: Fifteen patients of macromastia with minor and moderate breast ptosis were treated by using a breast augmentation with the anatomic implant under the breast gland. The results were... | ['Adult', 'Breast Diseases', 'Breast Implantation', 'Breast Implants', 'Female', 'Humans'] | 17,017,140 | [['M01.060.116'], ['C17.800.090'], ['E02.218.565.210', 'E04.650.210', 'E04.680.500.210'], ['E07.695.140'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Maternal behavior predicts neural underpinnings of inhibitory control in preschoolers. | Separate lines of research have revealed that the rapid development of inhibitory control in the preschool period is closely tied to normative brain development and influenced by early mother-child interactions. One potential theory is that maternal behavior in the context of early interactions influences the neural un... | ['Adult', 'Child', 'Child Behavior', 'Child Development', 'Child, Preschool', 'Electroencephalography', 'Evoked Potentials', 'Executive Function', 'Female', 'Humans', 'Inhibition, Psychological', 'Male', 'Maternal Behavior', 'Mother-Child Relations', 'Social Support'] | 29,806,227 | [['M01.060.116'], ['M01.060.406'], ['F01.145.179'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500', 'G11.561.200.500'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.405'], ['F01.829.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Application of chemometric approach for development and validation of high performance liquid chromatography method for estimation of ropinirole hydrochloride. | A systematic Quality by Design approach was employed for developing an isocratic reversed-phase liquid chromatographic technique for the estimation of ropinirole hydrochloride in bulk drug and pharmaceutical formulations. LiChrospher RP 18-5 Endcapped column (25 cm ? 4.6 mm id) at ambient temperature (25 ± 2°C) was use... | ['Chromatography, High Pressure Liquid', 'Drug Compounding', 'Indoles'] | 31,465,611 | [['E05.196.181.400.300'], ['E05.916.270'], ['D03.633.100.473']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pilot study on probe-based confocal laser endomicroscopy for colorectal neoplasms: an initial experience in Japan. | BACKGROUND: The aim of this pilot study is to investigate the diagnostic yield of probe-based confocal laser endomicroscopy (pCLE) in the evaluation of depth of invasion in colorectal lesions.METHODS: Patients with colorectal lesions eligible for either endoscopic treatment or surgery were enrolled in the study. Tumor'... | ['Adult', 'Aged', 'Colonoscopy', 'Colorectal Neoplasms', 'Female', 'Humans', 'Japan', 'Male', 'Microscopy, Confocal', 'Middle Aged', 'Neoplasm Invasiveness', 'Pilot Projects', 'Young Adult'] | 29,700,599 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Victim and citizen perspectives on sexual offender policy. | At any point, the "best practices" for managing sexual offenders typically derive from the prevailing social policy regarding such offenders. Social policy perspectives held by victims, citizens in the community, and sexual offender experts often are quite different, with victims, their advocates, and citizens supporti... | ['Adult', 'Attitude', 'Child', 'Child Abuse, Sexual', 'Commitment of Mentally Ill', 'Crime Victims', 'Criminal Law', 'Humans', 'Public Policy', 'Sex Offenses', 'United States'] | 12,839,919 | [['M01.060.116'], ['F01.100'], ['M01.060.406'], ['I01.198.240.748.300', 'I01.198.240.856.350.250.255', 'I01.880.735.900.350.250.255'], ['F04.096.544.335.200', 'N03.706.535.351.200'], ['M01.135'], ['I01.198.290', 'I01.880.604.583.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.655.500.608', 'I01.880.604.82... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Distribution of palatal and other arteries in cleft and non-cleft human palates. | Cleft lip and cleft palate are two possible effects of fusion failure of embryonic facial processes. Aberrant facial morphogenesis suggest aberrant arterial distribution. Prompted by surgical need, studies detailing major branches of the third or pterygopalatine portion of the maxillary artery acquire practical signifi... | ['Alveolar Process', 'Arteries', 'Cleft Palate', 'Face', 'Humans', 'Maxillary Artery', 'Orbit', 'Palate'] | 264,275 | [['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['A07.015.114'], ['C05.500.460.185', 'C05.660.207.540.460.185', 'C07.320.440.185', 'C07.465.525.185', 'C07.650.500.460.185', 'C07.650.525.185', 'C16.131.621.207.540.460.185', 'C16.131.850.500.460.185', 'C16.131.850.525.185'], ['A01.456.505'], ['B01... | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Damage control surgery in neonates: Lessons learned from the battlefield. | INTRODUCTION: Mortality for neonates requiring surgery for serious pathology such as NEC, remains high. Damage control surgery (DCS) has evolved as an operative strategy in battlefield trauma that sacrifices the completeness of the initial surgery to address the deadly triad of acidosis, hypothermia and coagulopathy. T... | ['Case-Control Studies', 'Emergencies', 'Enterocolitis, Necrotizing', 'Humans', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Intestinal Volvulus', 'Peritonitis'] | 31,103,271 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['C06.405.205.596.700', 'C06.405.469.363.700'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614'], ['C06.405.469.531.568', 'C23.300.970.500'], ['C01.463.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Isolation and characterization of myosin heavy chain isozymes of the bovine conduction system. | To determine the characteristics of cardiac myosin in the conduction system, a pure Purkinje fiber preparation, consisting of atrioventricular nodes and the ventricular conduction system, was obtained from bovine hearts. Two types of myosin heavy chain isozymes, alpha-type and beta-type, were fractionated by affinity c... | ['Animals', 'Antibodies, Monoclonal', 'Atrioventricular Node', 'Calcium-Transporting ATPases', 'Cattle', 'Chromatography, Affinity', 'Electrophoresis, Polyacrylamide Gel', 'Enzyme-Linked Immunosorbent Assay', 'Heart Conduction System', 'Heart Ventricles', 'Immunologic Techniques', 'Myocardium', 'Myosins', 'Peptide Frag... | 2,960,469 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A07.541.409.147'], ['D08.811.277.040.025.314.250', 'D12.776.157.530.450.250.500', 'D12.776.157.530.813.250', 'D12.776.543.585.450.250.500', 'D12.776.543.585.813.250'], ['B01.050.150.900.649.313.500.380.271'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exercise, Dehydroepiandrosterone (DHEA), and Mood Change: A Rationale for the "Runners High"? | BACKGROUND: Although exercise has been shown to improve mood and well-being, the precise mechanism remains unknown. Neurosteroids are important neuroactive molecules with demonstrated involvement in several neurophysiological and disease processes. Previous research has noted neurosteroid changes in dehydroepiandroster... | ['Adult', 'Affect', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Dehydroepiandrosterone', 'Exercise', 'Female', 'Humans', 'Male', 'Middle Aged', 'Running', 'Surveys and Questionnaires'] | 29,911,751 | [['M01.060.116'], ['F01.470.047'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D04.210.500.054.079.429.625', 'D04.210.500.578.502.400', 'D06.472.040.502.400', 'D06.472.334.851.968.952'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M0... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Sphingosine kinase type 1 induces G12/13-mediated stress fiber formation, yet promotes growth and survival independent of G protein-coupled receptors. | Sphingosine 1-phosphate (S1P) is the ligand for a family of specific G protein-coupled receptors (GPCRs) that regulate a wide variety of important cellular functions, including growth, survival, cytoskeletal rearrangements, and cell motility. However, whether it also has an intracellular function is still a matter of g... | ['Animals', 'Cell Division', 'Cell Movement', 'Cells, Cultured', 'Embryo, Mammalian', 'Focal Adhesion Kinase 1', 'Focal Adhesion Protein-Tyrosine Kinases', 'Focal Adhesions', 'GTP-Binding Protein alpha Subunits, G12-G13', 'Lysophospholipids', 'Mice', 'Phosphotransferases (Alcohol Group Acceptor)', 'Protein-Tyrosine Kin... | 12,963,721 | [['B01.050'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['A16.254'], ['D08.811.913.696.620.682.725.049.500', 'D12.776.744.493'], ['D08.811.913.696.620.682.725.049', 'D12.644.360.287', 'D12.776.476.287'], ['A11.284.149.165.165.285'], ['D08.811.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A comparison of self-reported hearing and pure tone threshold average in the Iowa Farm Family Health and Hazard Survey. | BACKGROUND: Self-reported hearing measures are useful for surveying hearing loss in a population because they are short, and easy to administer by either questionnaire or telephone. This study aims to assess the performance of several self-reported hearing measures to identify hearing loss in a group of Iowa farmers.ME... | ['Age Distribution', 'Age Factors', "Agricultural Workers' Diseases", 'Audiometry, Pure-Tone', 'Auditory Threshold', 'Health Surveys', 'Hearing Loss', 'Humans', 'Iowa', 'Male', 'Mass Screening', 'Middle Aged', 'Prevalence', 'Self Disclosure', 'Sensitivity and Specificity', 'Surveys and Questionnaires'] | 16,537,314 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['N05.715.350.075', 'N06.850.490.250'], ['C24.080'], ['E01.370.382.375.060.055'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['C09.218.458.341', 'C10.597.751.418... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Risk of type 2 diabetes mellitus and acute cardiovascular disorders in patients with early disturbances of carbohydrate metabolism]. | The aim of this work was to estimate the relative risk (RR) of type 2 diabetes mellitus (DM2) and cardiovascular diseases, total and cardiovascular mortality in patients with disturbances of carbohydrate metabolism revealed in the prospective study carried out in 2009 that included patients found to have disturbances o... | ['Acute Disease', 'Adult', 'Carbohydrate Metabolism', 'Cardiovascular Diseases', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Retrospective Studies', 'Risk Factors', 'Russia', 'Time Factors'] | 23,516,850 | [['C23.550.291.125'], ['M01.060.116'], ['G02.111.158', 'G03.191'], ['C14'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.116.630'], ['E05.318.372.500.50... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Adapting evidence-based interventions using a common theory, practices, and principles. | Hundreds of validated evidence-based intervention programs (EBIP) aim to improve families' well-being; however, most are not broadly adopted. As an alternative diffusion strategy, we created wellness centers to reach families' everyday lives with a prevention framework. At two wellness centers, one in a middle-class ne... | ['Child', 'Child, Preschool', 'Diffusion of Innovation', 'Evidence-Based Practice', 'Humans', 'Obesity', 'Outcome and Process Assessment, Health Care', 'Parenting', 'Parents', 'Preventive Health Services', 'Primary Health Care', 'Residence Characteristics', 'Socioeconomic Factors'] | 24,079,747 | [['M01.060.406'], ['M01.060.406.448'], ['L01.143.320'], ['H02.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120.699.500'], ['N04.761.559', 'N05.715.360.575'], ['F01.829.263.370.310'], ['F01.829.263.500.320', 'I0... | ['Named Groups [M]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social P... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
[Peripheral venous catheter embolism]. | The accidental embolization of peripheral venous catheter fragments seems to be a rare event. Removal of the catheter embolus is usually recommended, because of the high morbidity and mortality rates from sepsis, perforation, thrombosis and arrhythmias. We report a case, in which the diagnosis was made 17 years after t... | ['Adult', 'Catheterization, Peripheral', 'Embolism', 'Female', 'Foreign-Body Migration', 'Humans', 'Lung', 'Radiography', 'Time Factors', 'Tomography Scanners, X-Ray Computed'] | 9,686,081 | [['M01.060.116'], ['E02.148.224', 'E04.100.814.529.937', 'E04.502.382.937', 'E05.157.375'], ['C14.907.355.350'], ['C26.392.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['E01.370.350.700'], ['G01.910.857'], ['E07.913']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Translation and cultural adaptation of the Mother-Generated Index into Brazilian Portuguese: A postnatal quality of life study. | OBJECTIVE: quality of life issues are central to maternal health and well-being. Within the context of a study examining postnatal quality of life, we set out to translate into Brazilian Portuguese the Mother-Generated Index and ensure its cross-cultural adaption for use in a Brazilian context.DESIGN: the Mother-Genera... | ['Adaptation, Psychological', 'Brazil', 'Cross-Cultural Comparison', 'Ethnic Groups', 'Female', 'Humans', 'Maternal-Child Health Services', 'Midwifery', 'Mothers', 'Parturition', 'Pregnancy', 'Quality of Life', 'Surveys and Questionnaires', 'Translations'] | 25,935,233 | [['F01.058'], ['Z01.107.757.176'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['M01.686.754', 'N01.224.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.143.130.660', 'N02.421.143.620.275'], ['H02.478.676.416'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M01.620.630'], ['G08.686.78... | ['Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equip... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Frequency of venous thrombosis in patients with an exacerbation of chronic obstructive lung disease. | The presence or absence of venous thrombosis was determined in 29 patients with an acute exacerbation of chronic obstructive lung disease by the technique of autologous platelet labelling with indium-111. Deep venous thrombosis was diagnosed in 13 patients and in nine of these patients thrombosis was located proximal t... | ['Aged', 'Blood Platelets', 'Female', 'Humans', 'Indium', 'Lung Diseases, Obstructive', 'Male', 'Middle Aged', 'Pulmonary Embolism', 'Radioisotopes', 'Thrombophlebitis'] | 6,612,652 | [['M01.060.116.100'], ['A11.118.188', 'A15.145.229.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.381', 'D01.552.544.381'], ['C08.381.495'], ['M01.060.116.630'], ['C08.381.746', 'C14.907.355.350.700'], ['D01.496.749'], ['C14.907.355.830.925.770', 'C14.907.617.718.788', 'C14.907.940.740.910']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Biology and modulation of multidrug resistance (MDR) in hematological malignancies. | Drug resistance is one of the most significant impediments in the treatment of hematological malignancies. There have been a number of studies on the incidence of P-GP expression in tumor cells or tissues, where detectable level of P-GP has been found in all types of hematological malignancies. P-GP expression and sign... | ['ATP-Binding Cassette Transporters', 'Drug Resistance, Multiple', 'Gene Expression Profiling', 'Hematologic Neoplasms', 'Humans', 'Tumor Cells, Cultured', 'Vincristine'] | 12,430,927 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['G07.690.773.984.300'], ['E05.393.332'], ['C04.588.448', 'C15.378.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.860'], ['D03.132.436.681.827.817', 'D03.633.100.473.402.681.827.817', 'D03.633.100.496.500.5... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genome-Wide Mapping of the Binding Sites and Structural Analysis of Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 2 Reveal that It Is a DNA-Binding Transcription Factor. | UNLABELLED: The oncogenic herpesvirus Kaposi's sarcoma-associated herpesvirus (KSHV) is known to encode four viral interferon regulatory factors (vIRF1 to -4) to subvert the host antiviral immune response, but their detailed DNA-binding profiles as transcription factors in the host remain uncharacterized. Here, we firs... | ['Binding Sites', 'Crystallography, X-Ray', 'DNA Mutational Analysis', 'DNA, Viral', 'DNA-Binding Proteins', 'Herpesvirus 8, Human', 'Host-Pathogen Interactions', 'Humans', 'Immune Evasion', 'Interferon Regulatory Factors', 'Models, Molecular', 'Protein Binding', 'Protein Conformation', 'Transcription Factors', 'Viral ... | 26,537,687 | [['G02.111.570.120'], ['E05.196.309.742.225'], ['E05.393.760.700.300'], ['D13.444.308.568'], ['D12.776.260'], ['B04.280.210.400.700.330', 'B04.280.382.400.700.330', 'B04.613.204.500.700.330'], ['G06.462', 'G16.527.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G06.462.400', 'G12.413', 'G16.527.200.700'], ['D... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of a distinctive pattern of periovulatory leptin secretion and its relationship with ovulation rate and luteal function in swine with obesity/leptin resistance. | Patterns of leptin secretion during the estrous cycle and the possible relationship of changes in circulating leptin during the periovulatory period with ovarian function in sows of obese (Iberian breed) and lean genotype (Large White x Landrace) were evaluated in two consecutive experiments. Plasma leptin concentratio... | ['Animals', 'Corpus Luteum', 'Female', 'Genotype', 'Leptin', 'Obesity', 'Ovulation', 'Ovulation Induction', 'Swine', 'Thinness'] | 22,841,857 | [['B01.050'], ['A05.360.319.114.630.278', 'A06.300.312.497.278'], ['G05.380'], ['D06.472.699.042.500', 'D12.644.276.024.500', 'D12.644.548.011.500', 'D12.776.467.024.500', 'D23.529.024.500'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120.699.500'], ['G08.686.784.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Laparoscopic Surgery for isolated lymph nodes recurrence in gynecology. Experience in Argentina.] | Objectives: to describe the perioperative and oncological outcomes of a serie of cases treated with laparoscopic surgery for isolated nodal metastasis of gynecologic malignancies at the Gynecology Service of Hospital Italiano de Buenos Aires and conduct a literature review on the surgical treatment provided to patients... | ['Aged', 'Argentina', 'Carcinoma', 'Cytoreduction Surgical Procedures', 'Disease-Free Survival', 'Female', 'Genital Neoplasms, Female', 'Humans', 'Laparoscopy', 'Lymph Node Excision', 'Middle Aged', 'Perioperative Period', 'Recurrence', 'Treatment Outcome'] | 30,273,530 | [['M01.060.116.100'], ['Z01.107.757.077'], ['C04.557.470.200'], ['E04.166'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['C04.588.945.418', 'C13.351.937.418'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Stability of Diazoxide in Extemporaneously Compounded Oral Suspensions. | The objective of this study was to evaluate the stability of diazoxide in extemporaneously compounded oral suspensions. Oral suspensions of diazoxide 10 mg/mL were prepared from either bulk drug or capsules dispersed in either Oral Mix or Oral Mix Sugar Free. These suspensions were stored at 5°C and 25°C/60%RH in bottl... | ['Capsules', 'Chromatography, High Pressure Liquid', 'Diazoxide', 'Drug Compounding', 'Drug Stability', 'Drug Storage', 'Hydrogen-Ion Concentration', 'Spectrophotometry, Ultraviolet', 'Temperature'] | 27,727,306 | [['D26.255.150'], ['E05.196.181.400.300'], ['D02.886.590.700.135.300', 'D02.886.655.500.300', 'D03.633.100.174.300'], ['E05.916.270'], ['E05.916.330'], ['E05.916.350'], ['G02.300'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The More the Better? A Comparison of the Information Sources Used by the Public during Two Infectious Disease Outbreaks. | Recent infectious disease outbreaks have resulted in renewed recognition of the importance of risk communication planning and execution to public health control strategies. Key to these efforts is public access to information that is understandable, reliable and meets their needs for informed decision-making on protect... | ['Access to Information', 'Alberta', 'Canada', 'Disease Outbreaks', 'Health Knowledge, Attitudes, Practice', 'Health Literacy', 'Humans', 'Influenza A Virus, H1N1 Subtype', 'Influenza, Human', 'Internet', 'Mass Media', 'Public Health', 'Severe Acute Respiratory Syndrome'] | 26,485,302 | [['I01.880.604.473.352.500.030', 'L01.143.024', 'L01.737.030'], ['Z01.107.567.176.064'], ['Z01.107.567.176'], ['N06.850.290'], ['F01.100.150.500', 'N05.300.150.410'], ['I02.233.332.186.500', 'L01.143.450.500', 'N02.421.726.407.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.405.400.214'], ... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Geographicals [Z]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
Infiltration of plasma rich in growth factors for osteoarthritis of the knee short-term effects on function and quality of life. | PURPOSE: Osteoarthritis (OA) is a highly prevalent, chronic, degenerative condition that generates a high expense. Alternative and co-adjuvant therapies to improve the quality of life and physical function of affected patients are currently being sought.METHODS: A total of 808 patients with knee pathology were treated ... | ['Female', 'Humans', 'Injections, Intra-Articular', 'Longitudinal Studies', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Osteoarthritis, Knee', 'Platelet-Derived Growth Factor', 'Platelet-Rich Plasma', 'Prospective Studies', 'Quality of Life', 'Recovery of Function', 'Statistics, Nonparametric', 'Surveys and Q... | 20,714,903 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.380'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C05.550.114.606.500', 'C05.799.613.500'], ['D12.644.276.910', 'D12.776.124.625', 'D12.776.467.910', 'D23.5... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Adolescent girls' perceived barriers to participation in physical activity. | Research shows a decline in physical activity levels during adolescence, particularly among girls. This study explored perceived barriers to participation in moderate and vigorous physical activity among adolescent girls who live in a large ethnoracially and socioeconomically diverse city. A total of 73 adolescent girl... | ['Adolescent', 'Attitude to Health', 'Body Image', 'Competitive Behavior', 'Female', 'Humans', 'Motor Activity', 'Social Environment', 'Surveys and Questionnaires'] | 16,689,442 | [['M01.060.057'], ['F01.100.150', 'N05.300.150'], ['F01.752.747.792.110', 'F02.463.593.112'], ['F01.145.813.105'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.632', 'G11.427.410.698'], ['I01.880.853.500'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Myeloid and plasmacytoid dendritic cells transfer HIV-1 preferentially to antigen-specific CD4+ T cells. | Dendritic cells (DCs) are essential antigen-presenting cells for the induction of T cell immunity against pathogens such as human immunodeficiency virus (HIV)-1. At the same time, HIV-1 replication is strongly enhanced in DC-T cell clusters, potentially undermining this process. We found that immature CD123(+) plasmacy... | ['Antigen Presentation', 'Antigens, Viral', 'CD11 Antigens', 'CD4-Positive T-Lymphocytes', 'Cytomegalovirus', 'DNA Primers', 'Dendritic Cells', 'Flow Cytometry', 'Fluoresceins', 'HIV-1', 'Humans', 'Interferon-alpha', 'Interleukin-3 Receptor alpha Subunit', 'Polymerase Chain Reaction', 'Receptors, CCR5', 'Receptors, CXC... | 15,967,828 | [['G12.119', 'G12.450.050.400.070'], ['D23.050.327'], ['D12.776.395.550.200.074', 'D12.776.543.550.200.093', 'D23.050.301.350.074'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['B04.280.382.150.150'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['A... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Insulin resistance precedes microalbuminuria in patients with insulin-dependent diabetes mellitus. | BACKGROUND: Insulin resistance has been associated with hypertension and with renal complications in patients with type 1 diabetes mellitus. Causal relationships have not been fully explained.METHODS: We investigated whether insulin resistance precedes microalbuminuria by measuring insulin resistance with a euglycaemic... | ['Adolescent', 'Adult', 'Albuminuria', 'Child', 'Diabetes Mellitus, Type 1', 'Follow-Up Studies', 'Glucose', 'Glucose Clamp Technique', 'Humans', 'Insulin Resistance', 'Reference Values'] | 9,870,469 | [['M01.060.057'], ['M01.060.116'], ['C12.777.934.734.269', 'C13.351.968.934.734.269', 'C23.888.942.750.269'], ['M01.060.406'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D09.947.875.359.448'], ['E01.370.225.124.100.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A long-term comparison of galantamine and donepezil in the treatment of Alzheimer's disease. | OBJECTIVE: To compare the long-term efficacy and safety of galantamine 24 mg/day and donepezil 10 mg/day in patients with Alzheimer's disease.PATIENTS AND STUDY DESIGN: This was a rater-blinded, randomised, parallel-group multicentre study (18 outpatient clinics) in the UK. 182 patients (69 male, 113 female) with Alzhe... | ['Aged', 'Alzheimer Disease', 'Cognition', 'Donepezil', 'Drug Administration Schedule', 'Female', 'Galantamine', 'Humans', 'Indans', 'Male', 'Mental Status Schedule', 'Piperidines', 'Time', 'Treatment Outcome'] | 12,875,613 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['F02.463.188'], ['D02.455.426.559.847.486.487.280', 'D03.383.621.238', 'D04.615.486.487.280'], ['E02.319.283'], ['D03.132.052.500', 'D03.633.100.079.525'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.847.486.487... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The transmembrane domain of the Staphylococcus aureus ESAT-6 component EssB mediates interaction with the integral membrane protein EsaA, facilitating partially regulated secretion in a heterologous host. | The ESAT-6-like secretion system (ESS) of Staphylococcus aureus plays a significant role in persistent infections. EssB is a highly conserved bitopic ESS protein comprising a cytosolic N-terminus, single transmembrane helix and a C-terminus located on the trans-side of the membrane. Six systematic truncations covering ... | ['Bacterial Proteins', 'Humans', 'Membrane Proteins', 'Protein Binding', 'Protein Domains', 'Protein Transport', 'Staphylococcal Infections', 'Staphylococcus aureus'] | 29,737,367 | [['D12.776.097'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.275.750', 'G02.111.570.820.709.610.500'], ['G03.143.700'], ['C01.150.252.410.868'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.510.100.750.750.100', 'B03.510.400.790... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of erythropoietin, bromocryptine and hydralazine on testicular function in rats with chronic renal failure. | We evaluated the effects of chronic renal failure (CRF) on testicular function and semen physiology. A CRF model was created in 48 male rats by performance of five-sixths nephrectomies in two-stage procedures, and a control (group A) by two-stage sham operation on six male rats. Seven weeks later, serum urea and creati... | ['Animals', 'Bromocriptine', 'Creatinine', 'Epididymis', 'Erythropoietin', 'Fertility', 'Fertilization in Vitro', 'Hematocrit', 'Humans', 'Hydralazine', 'Kidney Failure, Chronic', 'Male', 'Prolactin', 'Rats', 'Rats, Wistar', 'Sperm Motility', 'Spermatozoa', 'Testis', 'Testosterone', 'Urea'] | 9,197,918 | [['B01.050'], ['D03.132.327.412.100', 'D03.633.400.439.131', 'D03.633.400.562.100'], ['D03.383.129.308.207'], ['A05.360.444.371'], ['D12.644.276.374.410.240.150', 'D12.776.395.240.150', 'D12.776.467.374.410.240.150', 'D23.529.374.410.240.150'], ['G08.686.210'], ['E02.875.800.750', 'E05.820.800.750'], ['E01.370.225.625.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Successful treatment of cold agglutinin disease with anti-CD20 antibody (rituximab) in a patient with systemic lupus erythematosus. | Cold agglutinin disease (CAD) is a rare cause of anaemia in patients with systemic lupus erythematosus (SLE). CAD is usually refractory to glucocorticosteroid, and other immunosuppressive and/or cytotoxic therapies. We report the case of a 55-years old woman with SLE and CAD that did not respond to high-dose methylpred... | ['Anemia, Hemolytic, Autoimmune', 'Antibodies, Monoclonal', 'Antibodies, Monoclonal, Murine-Derived', 'Antigens, CD20', 'Female', 'Humans', 'Immunologic Factors', 'Lupus Erythematosus, Systemic', 'Middle Aged', 'Rituximab'] | 17,120,596 | [['C15.378.071.141.125', 'C20.111.175'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.224.075', 'D12.776.124.790.651.114.224.075', 'D12.776.377.715.548.114.224.284'], ['D23.050.301.264.035.120', 'D23.050.301.264.051.120', 'D23.101.100.110.120',... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Synthesis of photoresponsive hybrid alginate hydrogel with photo-controlled release behavior. | A photoresponsive hybrid alginate hydrogel was successfully prepared by Ca(2+)-mediated crosslinking reaction with a mixture of â-cyclodextrin-grafted alginate (â-CD-Alg) and diazobenzene-modified poly(ethylene glycol) (Az2-PEG). The water-soluble Az2-PEG exhibits efficient trans-to-cis isomerization of the terminal az... | ['Alginates', 'Delayed-Action Preparations', 'Glucuronic Acid', 'Hexuronic Acids', 'Hydrogel, Polyethylene Glycol Dimethacrylate', 'Hydrogen-Ion Concentration', 'Microscopy, Electron, Scanning', 'Polyethylene Glycols', 'Rhodamines', 'Spectrometry, Fluorescence', 'Spectroscopy, Fourier Transform Infrared', 'Ultraviolet ... | 25,563,940 | [['D09.698.068'], ['D26.255.210', 'E02.319.300.253'], ['D02.241.081.844.915.162.249', 'D02.241.152.811.162.500', 'D02.241.511.902.915.162.500', 'D09.811.922.162.500'], ['D02.241.081.844.915.400', 'D02.241.152.811.400', 'D02.241.511.902.915.400', 'D09.811.922.400'], ['D02.033.455.250.700.485', 'D05.750.219.500', 'D05.75... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Schistosomiasis mansoni: dynamics of transmission]. | The following remarks were addressed at the round table that discussed the alternative approaches to schistosomiasis control. The address begins with a short analysis of the progressive spread of the area of distribution of the disease, and of the difficulties faced by those in charge of control programs, conventional ... | ['Animals', 'Disease Vectors', 'Health Policy', 'Host-Parasite Interactions', 'Humans', 'Schistosoma mansoni', 'Schistosomiasis mansoni', 'Snails'] | 3,151,087 | [['B01.050'], ['N06.850.335.188', 'N06.850.520.203.375'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['G16.527.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.500.500.736.715.770.680.700'], ['C01.610.335.865.859.576', 'C01.920.922.576'], ['B01.050.500.644.400.750']] | ['Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
[Characteristic of the univalent behavior in a series of monosomic lines of wheat Milturum 553 cultivar in the second meiotic division of microsporocytes]. | The investigations fulfilled resulted in defining the character of the univalent behavior of each chromosome of the wheat cultivar Milturum 553 in the second meiotic division of the microsporocytes. General regularities of the hemizygous state of chromosomes in realisation of mechanisms of the changes of pole orientati... | ['Anaphase', 'Chromosomes, Plant', 'Genotype', 'Meiosis', 'Metaphase', 'Triticum'] | 14,650,326 | [['G04.144.220.220.687.222', 'G04.144.220.220.781.050', 'G05.113.220.687.250', 'G05.113.220.781.050'], ['A11.284.187.560', 'A18.005', 'G05.360.162.560'], ['G05.380'], ['G04.144.220.220.687', 'G05.113.220.687'], ['G04.144.220.220.687.625', 'G04.144.220.220.781.625', 'G05.113.220.687.625', 'G05.113.220.781.625'], ['B01.6... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prospective per diem rates for skilled nursing care. | On July 1, 1998, Medicare's cost-related reimbursement method for skilled nursing facility care was replaced with a prospective payment system that includes a case-mix adjustment based on the Resource Utilization Groups to which Medicare residents are assigned. Shortly thereafter, Congress modified the new system in re... | ['Accounting', 'Activities of Daily Living', 'Aged', 'Bankruptcy', 'Centers for Medicare and Medicaid Services, U.S.', 'Diagnosis-Related Groups', 'Financial Management', 'Health Care Sector', 'Humans', 'Medicare', 'Nursing Assessment', 'Prospective Payment System', 'Rate Setting and Review', 'Skilled Nursing Facilitie... | 12,079,151 | [['N03.219.463.030'], ['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['N03.219.463.045'], ['I01.409.418.750.600.310', 'N03.540.348.500.500.600.550'], ['N03.219.521.710.305.200.080'], ['N03.219.463'], ['J01.576.489', 'N03.219.650'], ['B01.050.150.900.649.313.988.400.112.40... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Working memory performance impaired after exposure to acute social stress: The evidence comes from ERPs. | Using event-related potentials (ERPs), we examined the time course of 39 healthy novice drivers during a blocked working memory task (numerical N-back) under acute social stress or control conditions, which were induced by the Trier Social Stress Task (TSST) or control procedure. Subjective measures were used to assess... | ['Adult', 'Evoked Potentials', 'Female', 'Humans', 'Male', 'Memory, Short-Term', 'Mental Processes', 'Neuropsychological Tests', 'Reaction Time', 'Stress, Psychological', 'Young Adult'] | 28,851,617 | [['M01.060.116'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.407'], ['F02.463'], ['F04.711.513'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F01.145.126.990', 'F02.830.900'], ['M01.060.116.815']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Is active surveillance a safe alternative in the management of localized prostate cancer? Pathological features of radical prostatectomy specimens in potential candidates for active surveillance. | INTRODUCTION AND OBJECTIVE: Active surveillance (AS) has become an accepted alternative for patients with low risk prostate cancer. The purpose of AS is to defer definitive therapy in these patients to avoid treatment-related complications. Our aim was to determine the pathological features of the surgical specimen fro... | ['Adult', 'Aged', 'Biopsy', 'Chi-Square Distribution', 'Disease Management', 'Humans', 'Lymph Nodes', 'Male', 'Middle Aged', 'Neoplasm Grading', 'Neoplasm Staging', 'Prostate', 'Prostate-Specific Antigen', 'Prostatectomy', 'Prostatic Neoplasms', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors', 'Time Factors'... | 24,856,482 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['N04.590.607'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Co-SLD suppressed the growth of oral squamous cell carcinoma via disrupting mitochondrial function. | To evaluate the safety and efficacy of novel cobalt complex with sulindac (Co-SLD), the zebrafish and oral squamous cell carcinoma CAL27 were investigated in the present study. The developmental toxicity of Co-SLD ranging from 5 to 20 ìM was determined by exposure to 3-144-h post-fertilization (hpf) zebrafish. Our data... | ['Animals', 'Antineoplastic Agents', 'Apoptosis', 'Carcinoma, Squamous Cell', 'Cell Cycle Checkpoints', 'Cell Line, Tumor', 'Cell Proliferation', 'Cobalt', 'Coordination Complexes', 'Dose-Response Relationship, Drug', 'Humans', 'Locomotion', 'Mitochondria', 'Mouth Neoplasms', 'Sulindac', 'Zebrafish'] | 31,062,618 | [['B01.050'], ['D27.505.954.248'], ['G04.146.954.035'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['G04.144.109'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['D01.234', 'D02.257'], ['G07.690.773.875', 'G07.690.936.500... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endothelial cell oxidative stress and signal transduction. | Endothelial dysfunction (ED) is an early event in atherosclerotic disease, preceding clinical manifestations and complications. Increased reactive oxygen species (ROS) have been implicated as important mechanisms that contribute to ED, and ROS's may function as intracellular messengers that modulate signaling pathways.... | ['Arteriosclerosis', 'Endothelial Cells', 'Gene Expression', 'Homocysteine', 'Humans', 'Hyperhomocysteinemia', 'Lipoproteins, LDL', 'Mitogen-Activated Protein Kinases', 'Oxidative Stress', 'Reactive Oxygen Species', 'Signal Transduction', 'Umbilical Veins'] | 15,693,275 | [['C14.907.137.126'], ['A11.436.275'], ['G05.297'], ['D02.886.030.498', 'D12.125.166.498'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.320.565.100.480', 'C18.452.603.378', 'C18.452.648.100.480', 'C18.654.521.500.133.699.418'], ['D10.532.515', 'D12.776.521.550'], ['D08.811.913.696.620.682.700.567', 'D12.644.... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantification of the impact of the offshore petrochemical industrial park on ambient ozone using photochemical grid modeling and assessment monitoring. | This study integrated the results of photochemical grid modeling and assessment monitoring to quantify the impact of the offshore petrochemical industrial park (OPIP), with area of 26.03 km2, on ambient ozone in a coastal region of Taiwan. A highly repetitive ozone-spreading phenomenon in the adjacent OPIP area was obs... | ['Air Pollutants', 'Environmental Monitoring', 'Oil and Gas Industry', 'Ozone', 'Taiwan', 'Volatile Organic Compounds'] | 30,145,760 | [['D27.888.284.101'], ['N06.850.460.350.080', 'N06.850.780.375'], ['J01.576.655.875.750'], ['D01.362.670.600'], ['Z01.252.474.872', 'Z01.639.850'], ['D02.974']] | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Phosphorus metabolites in different muscles of the rat leg by 31P image-selected in vivo spectroscopy. | The difference in concentration of phosphorylated metabolites in muscles with different fiber composition was studied in vivo by localized 31P nuclear magnetic resonance spectroscopy in the rat hindlimb 120-160 microliters volumes were selected in regions containing the soleus and gastrocnemius muscles. Concentrations ... | ['Adenosine Triphosphate', 'Animals', 'Female', 'Hindlimb', 'Hydrogen-Ion Concentration', 'Magnetic Resonance Spectroscopy', 'Muscle Fibers, Skeletal', 'Muscle, Skeletal', 'Organ Specificity', 'Phosphates', 'Phosphocreatine', 'Phosphorus', 'Rats', 'Rats, Sprague-Dawley'] | 9,176,886 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A13.473'], ['G02.300'], ['E05.196.867.519'], ['A10.690.552.500.500', 'A11.620.249'], ['A02.633.567', 'A10.690.552.500'], ['G07.650'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.695.625.675.650'], ['D12.125.373.60... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prediction and characterisation of a highly conserved, remote and cAMP responsive enhancer that regulates Msx1 gene expression in cardiac neural crest and outflow tract. | Double knockouts of the Msx1 and Msx2 genes in the mouse result in severe cardiac outflow tract malformations similar to those frequently found in newborn infants. Despite the known role of the Msx genes in cardiac formation little is known of the regulatory systems (ligand receptor, signal transduction and protein-DNA... | ['Animals', 'Base Sequence', 'Computational Biology', 'Cyclic AMP-Dependent Protein Kinases', 'DNA Primers', 'Enhancer Elements, Genetic', 'Gene Expression Regulation, Developmental', 'Heart', 'Immunohistochemistry', 'In Situ Hybridization', 'MSX1 Transcription Factor', 'Mice', 'Mice, Transgenic', 'Molecular Sequence D... | 18,358,468 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['H01.158.273.180', 'L01.313.124'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G02.111.570.080.689.330', 'G05.360.080.689.330', 'G05.360.340.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Investigation of amine and polyol functionality in extracts of polyurethane wound management dressings using MALDI-MS. | Polyurethane (PU) foams used in wound management are produced by a reaction between aromatic diisocyanates and polyether polyols. There is concern that residues of these starting materials, which may contain aromatic amine functionality, may leach from the finished polymer during in vivo applications. Furthermore, olig... | ['Amines', 'Humans', 'Occlusive Dressings', 'Polymers', 'Polyurethanes', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization'] | 10,885,068 | [['D02.092'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.101.650'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['D02.241.081.251.944.750', 'D05.750.716.650', 'D25.720.327.782', 'D25.720.716.650', 'J01.637.051.720.327.782', 'J01.637.051.720.716.650', 'J01.637.412.700'], ['E05.196.566.755']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Role of abdominal ultrasonography in clinical staging of pancreatic carcinoma: a tertiary center experience. | INTRODUCTION: Various imaging modalities are used for the diagnosis and staging of pancreatic cancer. Abdominal ultrasonography is the most widely available method and usually the first -line diagnostic tool used in patients with suspicion of pancreatic carcinoma.OBJECTIVES: The aim of the study was to assess the clini... | ['Female', 'Humans', 'Intraoperative Period', 'Lymph Nodes', 'Lymphatic Metastasis', 'Male', 'Neoplasm Staging', 'Pancreatic Neoplasms', 'Poland', 'Prospective Studies', 'Sensitivity and Specificity', 'Tertiary Care Centers', 'Tomography, X-Ray Computed', 'Ultrasonography'] | 24,694,741 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374', 'N02.421.585.753.374'], ['A10.549.400', 'A15.382.520.604.412'], ['C04.697.650.560', 'C23.550.727.650.560'], ['E01.789.625'], ['C04.588.274.761', 'C04.588.322.475', 'C06.301.761', 'C06.689.667', 'C19.344.421'], ['Z01.542.248.679'], ['E05.318.372.500.750.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Effects of margarine compared with those of butter on blood lipid profiles related to cardiovascular disease risk factors in normolipemic adults fed controlled diets. | Effects of butter and 2 types of margarine on blood lipid and lipoprotein concentrations were compared in a controlled diet study with 23 men and 23 women. Table spreads, added to a common basal diet, provided 8.3% of energy as fat. Diets averaged 34.6% of energy as fat and 15.5% as protein. Each diet was fed for 5 wk ... | ['Adult', 'Aged', 'Butter', 'Cardiovascular Diseases', 'Cross-Over Studies', 'Dietary Fats', 'Energy Intake', 'Fatty Acids, Unsaturated', 'Female', 'Humans', 'Lipids', 'Male', 'Margarine', 'Middle Aged', 'Risk Factors', 'Sex Characteristics'] | 9,771,853 | [['M01.060.116'], ['M01.060.116.100'], ['D10.212.302.199', 'G07.203.300.350.100', 'G07.203.300.375.200', 'J02.500.350.100', 'J02.500.375.200'], ['C14'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['G07.203.650.240.340'], ['D10.251.355'], ['B01.0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Bacterial biosynthesis of a calcium phosphate bone-substitute material. | A species of Serratia bacteria produces nano-crystalline hydroxyapatite (HA) crystals by use of a cell-bound phosphatase enzyme, located both periplasmically and within extracellular polymeric materials. The enzyme functions in resting cells by cleaving glycerol-2-phosphate (G-2-P) to liberate free phosphate ions which... | ['Bone Substitutes', 'Calcium Phosphates', 'Coated Materials, Biocompatible', 'Crystallization', 'Materials Testing', 'Pilot Projects', 'Serratia', 'Surface Properties', 'Temperature', 'Titanium'] | 15,332,607 | [['D25.130.325', 'J01.637.051.130.325'], ['D01.029.260.700.675.374.075', 'D01.146.360', 'D01.695.625.675.650.075'], ['D25.130.420', 'J01.637.051.130.420'], ['E05.196.300', 'G02.171'], ['E05.570'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['B03.440.450.425.814', 'B03.660.250.150.... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
TWO CASES OF ACUTE ENDOPHTHALMITIS AFTER INTRAVITREAL DEXAMETHASONE IMPLANT INJECTION. | PURPOSE: To present two cases of acute endophthalmitis after intravitreal dexamethasone implant injection and discuss the management of intravitreal implant-associated endophthalmitis.METHODS: Two patients, who underwent intravitreal dexamethasone implant injection for macular edema secondary to diabetic retinopathy in... | ['Acute Disease', 'Aged', 'Dexamethasone', 'Drug Implants', 'Endophthalmitis', 'Female', 'Glucocorticoids', 'Humans', 'Intravitreal Injections', 'Macular Edema', 'Middle Aged', 'Retina', 'Visual Acuity'] | 26,426,482 | [['C23.550.291.125'], ['M01.060.116.100'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D26.255.210.315'], ['C01.375.265', 'C11.294.265'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.475.500'], ['C11.768.585.439.245'], ['M01.060.116.630... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Clinical factors that affect the outcomes after anatomical versus non-anatomical resection for hepatocellular carcinoma. | PURPOSE: For hepatocellular carcinoma (HCC), the superiority of anatomical resection (AR) over non-anatomical resection (NR) is still controversial. In this study, we assessed the potential benefits of AR for HCC.METHODS: We enrolled 173 consecutive patients with HCC who underwent hepatectomy in our hospital from Augus... | ['Aged', 'Bilirubin', 'Biomarkers, Tumor', 'Carcinoma, Hepatocellular', 'Disease-Free Survival', 'Female', 'Hepacivirus', 'Hepatectomy', 'Humans', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Patient Selection', 'Treatment Outcome', 'alpha-Fetoproteins'] | 27,502,598 | [['M01.060.116.100'], ['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['D23.101.140'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.57... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of catheter-based renal sympathetic denervation on 24-h ambulatory blood pressure in patients with resistant hypertension. | We investigated the effect of renal denervation on office blood pressure (OBP) and 24-h ambulatory blood pressure (BP) measurement (ABPM) at baseline and 6 months after intervention in 25 consecutive patients with resistant hypertension. Mean baseline 24-h ABPM and OBP were 158/88 mmHg and 169/96 mmHg, respectively. Pa... | ['Antihypertensive Agents', 'Blood Pressure Monitoring, Ambulatory', 'Female', 'Humans', 'Hypertension', 'Kidney', 'Male', 'Middle Aged', 'Sympathectomy'] | 24,432,803 | [['D27.505.954.411.162'], ['E01.370.370.140.100', 'E01.370.520.500.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['A05.810.453'], ['M01.060.116.630'], ['E04.525.210.105.800']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Combining metabolic pathway analysis with Evolutionary Game Theory: explaining the occurrence of low-yield pathways by an analytic optimization approach. | Elementary-mode analysis is a powerful method for detecting all potential pathways in a metabolic network and computing the associated molar yields. Metabolic pathways can be interpreted as different strategies of organisms. Thus, methods from Evolutionary Game Theory can be employed. In Flux Balance Analysis (FBA), it... | ['Biological Evolution', 'Cell Respiration', 'Enzymes', 'Fermentation', 'Game Theory', 'Linear Models', 'Metabolic Networks and Pathways', 'Metabolomics', 'Models, Biological'] | 21,620,931 | [['G05.045', 'G16.075'], ['G03.197', 'G04.270'], ['D08.811'], ['G02.111.158.249', 'G03.191.249'], ['G17.388'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['G03.493'], ['H01.158.201.586', '... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
"Once I'd done it once it was like writing your name": Lived experience of take-home naloxone administration by people who inject drugs. | BACKGROUND: The supply of naloxone, the opioid antagonist, for peer administration ('take-home naloxone' (THN)) has been promoted as a means of preventing opioid-related deaths for over 20 years. Despite this, little is known about PWID experiences of take-home naloxone administration. The aim of this study was to adva... | ['Adolescent', 'Adult', 'Drug Overdose', 'Female', 'Humans', 'Male', 'Middle Aged', 'Naloxone', 'Narcotic Antagonists', 'Peer Group', 'Qualitative Research', 'Self Care', 'Substance Abuse, Intravenous', 'Young Adult'] | 29,803,097 | [['M01.060.057'], ['M01.060.116'], ['C25.775.383', 'E02.319.306.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D03.132.577.249.706', 'D03.605.497.750', 'D03.633.400.686.750', 'D04.615.723.795.706'], ['D27.505.696.543', 'D27.505.696.663.850.512', 'D27.505.954.427.550'], ['F01.829.316.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Computer order entry system decreased use of sliding scale insulin regimens. | OBJECTIVES: Despite evidence documenting their ineffectiveness, sliding scale insulin is a commonly used regimen for glucose management for hospitalized patients with diabetes mellitus. At the Veterans Affairs Puget Sound Medical Center, where computer order entry has been mandated, we tested the hypothesis that an evi... | ['Acid-Base Equilibrium', 'Blood Glucose', 'Clinical Pharmacy Information Systems', 'Diabetic Ketoacidosis', 'Drug Administration Schedule', 'Drug Prescriptions', 'Hospitals, Veterans', 'Humans', 'Hydrogen-Ion Concentration', 'Hypoglycemic Agents', 'Insulin', 'Medical Records Systems, Computerized', 'Medication Systems... | 12,425,238 | [['G02.111.007', 'G02.300.176', 'G03.030', 'G07.410.110', 'G09.188.050'], ['D09.947.875.359.448.500'], ['N02.421.668.320.200', 'N04.452.515.095'], ['C18.452.076.176.652.500', 'C18.452.394.750.535', 'C19.246.099.812'], ['E02.319.283'], ['E02.319.307', 'N02.421.668.778.500'], ['N02.278.421.510.180.400'], ['B01.050.150.90... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Hormone receptor and HER2 assessment in breast carcinoma metastatic to bone: A comparison between FNA cell blocks and decalcified core needle biopsies. | BACKGROUND: Estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) immunohistochemistry (IHC) guide the clinical management of breast cancer metastases. Decalcification of bone core needle biopsies (CNBs) can affect IHC. In the current study, the authors sought to define... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Biopsy, Fine-Needle', 'Biopsy, Large-Core Needle', 'Bone Neoplasms', 'Bone and Bones', 'Breast Neoplasms', 'Carcinoma', 'Clinical Decision-Making', 'Cohort Studies', 'Female', 'Histocytological Preparation Techniques', 'Humans', 'In Situ Hybridization, Fluore... | 31,883,437 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['E01.370.225.500.384... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Surgery for hyperthyroidism: indications, pretreatment, operative strategy and results. | In an endemic area nodular toxic goitre is the dominating type of hyperthyroidism, while Graves' or Basedow's disease with diffuse toxic goitre accounts for only 25 to 30% of the patients. Since antithyroid drug therapy has poor permanent effect and recurrence rates of about 50 to 60% and radioiodine in turn requires h... | ['Adolescent', 'Adrenergic beta-Antagonists', 'Adult', 'Age Factors', 'Antithyroid Agents', 'Child', 'Drug Therapy, Combination', 'Female', 'Goiter, Endemic', 'Graves Disease', 'Humans', 'Hyperthyroidism', 'Iodine Radioisotopes', 'Preoperative Care', 'Recurrence'] | 6,194,731 | [['M01.060.057'], ['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['D06.347.100', 'D27.505.696.399.450.100'], ['M01.060.406'], ['E02.319.310'], ['C19.874.283.300'], ['C11.675.349.500', 'C19.874.283.605', 'C19.874.397.370', 'C20.111.555'], ['B01.05... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Polymethylmethacrylate particles inhibit osteoblastic differentiation of MC3T3-E1 osteoprogenitor cells. | Orthopedic wear debris has been implicated as a significant inhibitory factor of osteoblast differentiation. Polymethylmethacrylate (PMMA) particles have been previously shown to inhibit the differentiation of osteoprogenitors in heterogeneous murine marrow stromal cell cultures, but the effect of PMMA particles on pur... | ['3T3 Cells', 'Animals', 'Cell Differentiation', 'Culture Media, Conditioned', 'Dose-Response Relationship, Drug', 'Joint Prosthesis', 'Mice', 'Mice, Inbred C57BL', 'Osteoblasts', 'Osteogenesis', 'Polymethyl Methacrylate', 'Time Factors'] | 18,302,244 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['G04.152'], ['D27.720.470.305.250', 'E07.206.250'], ['G07.690.773.875', 'G07.690.936.500'], ['E07.695.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['A11.329.629'], ['G07.345.... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
High-yield affinity alkylation of the atrial natriuretic factor receptor binding site. | To facilitate characterization of the atrial natriuretic factor (ANF) receptor, we have developed an affinity labeling procedure, stepwise affinity labeling, which allows specific labeling of ANF binding sites in adrenal plasma membranes at high yields. An iodoacetyl (IAc-), bromoacetyl (BrAc-), or maleimidobenzoyl gro... | ['Adrenal Cortex', 'Affinity Labels', 'Alkylation', 'Amino Acid Sequence', 'Animals', 'Atrial Natriuretic Factor', 'Binding Sites', 'Binding, Competitive', 'Cattle', 'Cell Membrane', 'In Vitro Techniques', 'Kinetics', 'Molecular Sequence Data', 'Peptide Fragments', 'Receptors, Atrial Natriuretic Factor'] | 8,974,452 | [['A06.300.071.140'], ['D27.720.470.410.080'], ['G02.111.035', 'G02.607.094', 'G03.059'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['G02.111.570.120'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['B01.050.150.900.649.313.500.380.271'], ['A11.28... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The new proton pump inhibitor esomeprazole is effective as a maintenance therapy in GERD patients with healed erosive oesophagitis: a 6-month, randomized, double-blind, placebo-controlled study of efficacy and safety. | BACKGROUND: Esomeprazole, the S-isomer of omeprazole, is the first proton pump inhibitor to be developed as an optical isomer. In patients with erosive oesophagitis, esomeprazole has produced significantly greater healing rates and improved symptom resolution vs. omeprazole.AIM: This study assesses the efficacy of esom... | ['Administration, Oral', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Esomeprazole', 'Esophagitis, Peptic', 'Female', 'Gastroesophageal Reflux', 'Heartburn', 'Humans', 'Isomerism', 'Male', 'Middle Aged', 'Placebos', 'Proton Pump Inhibitors', 'Recurrence... | 11,421,866 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D02.886.640.074.500.500', 'D03.383.725.024.500.500', 'D03.633.100.103.034.500.500'], ['C06... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Arterial hypertension with hypopotassemia and hypochloremic metabolic alkalosis caused by abuse of a nasal spray]. | The case of a young woman, using a nasal spray containing corticosteroids, presenting hypertension systodiastolic, hypokalemia and hypochloremic metabolic alkalosis is presented. Clinical findings, similar to hyperfunction of the adrenal cortex, recovered quickly after discontinuation of the drug. The principal causes ... | ['Adolescent', 'Aerosols', 'Alkalosis', 'Chlorides', 'Female', 'Humans', 'Hypertension', 'Hypokalemia', 'Nasal Decongestants', 'Substance-Related Disorders'] | 6,197,683 | [['M01.060.057'], ['D20.280.055', 'D26.255.165.055'], ['C18.452.076.354'], ['D01.210.450.150', 'D01.248.497.158.215'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C18.452.950.565'], ['D27.505.954.411.793.610', 'D27.505.954.796.560'], ['C25.775', 'F03.900']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Males outperform females in translating social relations into spatial positions. | Research indicates that human males interact in groups, whereas females form one-on-one relationships. Whereas females excel in understanding intimate verbally-mediated social information, we hypothesized that males would be more sensitive to the spatial positions of friends within a group. In Study 1, we demonstrate t... | ['Female', 'Friends', 'Humans', 'Interpersonal Relations', 'Male', 'Mental Recall', 'Sex Characteristics', 'Social Behavior', 'Space Perception', 'Young Adult'] | 20,965,501 | [['M01.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F02.463.425.540.641'], ['G08.686.815'], ['F01.145.813'], ['F02.463.593.778'], ['M01.060.116.815']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Isolation of the gene encoding pilin of Bacteroides nodosus (strain 198), the causal organism of ovine footrot. | The gene for pilin, the monomeric protein subunit from which the pilus of Bacteroides nodosus is constructed, has been isolated. Isolation was achieved by cloning the fragmented genome of B. nodosus in Escherichia coli RR1 using the plasmid vector pBR322. Pilin-producing colonies were identified by screening with a col... | ['Animals', 'Bacterial Proteins', 'Bacteroides', 'Base Sequence', 'Cloning, Molecular', 'Fimbriae Proteins', 'Fimbriae, Bacterial', 'Foot Rot', 'Genes', 'Genes, Bacterial', 'Membrane Proteins', 'Sheep', 'Sheep Diseases'] | 6,146,535 | [['B01.050'], ['D12.776.097'], ['B03.440.080.094.152', 'B03.440.425.410.194.152'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D12.776.097.120.425', 'D12.776.543.100.300'], ['A11.284.180.285', 'A20.843'], ['C01.150.252.400.369', 'C22.394'], ['G05.360.340.024.340'], ['G05.360.340.024.34... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Modulation of murine macrophage function by methamphetamine. | The abuse of methamphetamine (MA) is an increasingly growing problem globally and produces serious side effects. In the present study, the immunomodulating effects of MA were examined on murine peritoneal macrophages after MA (5 mg/kg body weight) was administered daily orally for 2 wk. When purified macrophages were s... | ['Animals', 'Central Nervous System Stimulants', 'Hydrogen Peroxide', 'Lipopolysaccharide Receptors', 'Macrophages', 'Male', 'Methamphetamine', 'Mice', 'Oxidants', 'Peritoneum'] | 15,513,893 | [['B01.050'], ['D27.505.696.282', 'D27.505.954.427.220'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D12.776.395.550.448.100', 'D12.776.543.484.500.100', 'D12.776.543.550.418.100', 'D12.776.543.750.705.045', 'D23.050.301.264.900.045', 'D23.101.100.900.045'], ['A1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Continuous subarachnoid infusion of local anaesthetic. | We observed the sensory, motor and cardiovascular changes occurring during subarachnoid infusion of bupivacaine 0.125% at 15 ml.h-1 in six patients. After 1 h, motor block and lower sensory levels were consistent and predictable but upper sensory levels were variable. There was a moderate decrease in systolic blood pre... | ['Aged', 'Aged, 80 and over', 'Anesthesia, Spinal', 'Blood Pressure', 'Bupivacaine', 'Female', 'Humans', 'Male', 'Middle Aged', 'Motor Neurons', 'Nerve Block', 'Neurons, Afferent', 'Pulse', 'Time Factors'] | 8,494,139 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E03.155.086.331'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D02.065.199.239', 'D02.092.146.113.239'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.675.655.500', 'A11.671.655.500'], ['E03.155.086.711', 'E04.525.210.550'], ['A08.675.650'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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