Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Transcranial magnetic stimulation: experience, knowledge and attitudes of recipients. | OBJECTIVE: To examine the experience, knowledge and attitudes of recipients of transcranial magnetic stimulation (TMS) regarding the treatment. There have been no studies of patient views about TMS.METHOD: A 60-item survey was administered by telephone to persons with depressive illness who received TMS at Royal Hobart... | ['Adult', 'Aged', 'Attitude to Health', 'Cognition', 'Depressive Disorder', 'Electroconvulsive Therapy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Surveys and Questionnaires', 'Transcranial Magnetic Stimulation'] | 11,270,457 | [['M01.060.116'], ['M01.060.116.100'], ['F01.100.150', 'N05.300.150'], ['F02.463.188'], ['F03.600.300'], ['F04.570.200.583', 'F04.669.224.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['E02.621.820']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Is procalcitonin valuable in the differential diagnosis of testicular torsion and epididymo-orchitis. | OBJECTIVE: To evaluate the efficacy of procalcitonin (PCT) in the differential diagnosis of testicular torsion and epididymo-orchitis.METHODS: This experimental study was performed in the research laboratory of Dicle University, School of Medicine, Diyarbakir, Turkey between March and June 2008. The study included 24 m... | ['Animals', 'Biomarkers', 'Calcitonin', 'Calcitonin Gene-Related Peptide', 'Diagnosis, Differential', 'Epididymitis', 'Male', 'Orchitis', 'Protein Precursors', 'Rats', 'Rats, Wistar', 'Spermatic Cord Torsion'] | 20,174,733 | [['B01.050'], ['D23.101'], ['D06.472.699.150', 'D06.472.931.052', 'D12.644.400.095', 'D12.644.548.150', 'D12.776.631.650.095'], ['D12.644.400.097', 'D12.776.631.650.097'], ['E01.171'], ['C12.294.199'], ['C12.294.829.493', 'C19.391.829.493'], ['D12.776.811'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.90... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Colorectal cancer in Lagos: a critical review of 100 cases. | This study critically analysed the clinical presentation, diagnosis, treatment and outcome in 100 patients with colorectal cancer seen over a twelve year period (1988 to 1999). Comparing our findings with those obtained three decades ago at our institution allowed for determination of time trends. There were 48 males a... | ['Adult', 'Aged', 'Colorectal Neoplasms', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Nigeria', 'Postoperative Complications', 'Statistics, Nonparametric', 'Survival Rate', 'Time Factors', 'Treatment Outcome'] | 11,257,919 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.8... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Adherence to and effectiveness of positive airway pressure therapy in children with obstructive sleep apnea. | OBJECTIVES: Positive airway pressure therapy (PAP) is frequently used to treat children who have obstructive sleep apnea syndrome and do not respond to adenotonsillectomy. However, no studies have evaluated objectively adherence to PAP in children, and few studies have evaluated objectively the effectiveness of PAP. Th... | ['Adolescent', 'Child', 'Child, Preschool', 'Continuous Positive Airway Pressure', 'Double-Blind Method', 'Female', 'Humans', 'Male', 'Patient Compliance', 'Polysomnography', 'Positive-Pressure Respiration', 'Sleep Apnea, Obstructive', 'Treatment Outcome'] | 16,510,622 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E02.041.625.790.259', 'E02.880.820.790.259'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.750.500.600', 'F01.145.488.887.500.600', 'N05.300.150.800.500.600']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Successful prevention of local and cutaneous hypersensitivity reactions to seminal fluid with intravaginal cromolyn. | Seminal fluid hypersensitivity usually is characterized by postcoital vulvovaginal itching, swelling, redness, with or without systemic signs and symptoms. Efforts to manage this condition have either met with poor patient acceptance or have not been uniformly successful. We describe a 23-year-old atopic woman with doc... | ['Adult', 'Cromolyn Sodium', 'Dermatitis, Atopic', 'Female', 'Humans', 'Immunoglobulin E', 'Semen', 'Single-Blind Method', 'Skin Tests', 'Vagina'] | 1,905,663 | [['M01.060.116'], ['D03.383.663.283.266.300', 'D03.633.100.150.266.300'], ['C16.320.850.210', 'C17.800.174.193', 'C17.800.815.193', 'C17.800.827.210', 'C20.543.480.343'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.312', 'D12.776.124.790.651.114.619.312', 'D12.776.377.715.548.114.619.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Do sudden gains predict treatment outcome in social anxiety disorder? Findings from two randomized controlled trials. | OBJECTIVE: Sudden gains (SGs) have been found to occur during randomized controlled trials (RCTs) for social anxiety disorder (SAD). Evidence is mixed whether SGs relate to treatment outcome in SAD. We examined SGs in two RCTs for SAD.METHOD: Study 1 (N = 68) examined SGs in individual cognitive-behavioral therapy (CBT... | ['Adult', 'Cognitive Behavioral Therapy', 'Female', 'Humans', 'Male', 'Mindfulness', 'Phobia, Social', 'Psychotherapy, Group', 'Treatment Outcome', 'Young Adult'] | 31,430,688 | [['M01.060.116'], ['F04.754.137.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.551', 'F04.754.137.350.500'], ['F03.080.725.500'], ['F04.754.864.581'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mortality and prognostic factors of patients who have blood cultures performed in the emergency department: a cohort study. | BACKGROUND: Early identification and treatment of patients with severe infection improve their prognosis. The aims of this study were to describe the 30-day mortality and to identify prognostic factors among blood-cultured patients in a medical emergency department (MED).PATIENTS AND METHODS: This was a hospital-based ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bacteremia', 'Blood Culture', 'Emergency Service, Hospital', 'Female', 'Humans', 'Infections', 'Male', 'Middle Aged', 'Prognosis', 'Proportional Hazards Models', 'Prospective Studies', 'Risk Factors', 'Young Adult'] | 25,710,084 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['E01.370.225.875.185', 'E05.200.875.185'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01'],... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Monitoring on-line treated water and dialysate quality]. | INTRODUCTION: On line-treated water has been designed to obtain ultrapure water. This quality of water is obviously necessary to obtain ultrapure dialysate, although this is not the only condition. To keep the quality of the process, is necessary the continuous monitoring of the water treatment, dialysate and haemodial... | ['Hemodialysis Solutions', 'Water Microbiology', 'Water Purification'] | 18,816,207 | [['D26.776.708.322.651', 'D27.505.954.578.483.651', 'D27.720.752.483.651'], ['H01.158.273.540.274.777', 'N06.850.425.450'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900']] | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Memory impairment in rats after desflurane anesthesia is age and dose dependent. | Post-operative cognitive dysfunction (POCD) predominantly affects the elderly who suffer memory and concentration deficits after anesthesia and surgery. Animal studies have demonstrated anesthetic alone may contribute to POCD but results are variable and little is known about common anesthetics other than isoflurane. T... | ['Age Factors', 'Aging', 'Anesthetics, Inhalation', 'Animals', 'Desflurane', 'Dose-Response Relationship, Drug', 'Isoflurane', 'Male', 'Maze Learning', 'Memory Disorders', 'Rats', 'Rats, Sprague-Dawley', 'Time Factors'] | 25,380,590 | [['N05.715.350.075', 'N06.850.490.250'], ['G07.345.124'], ['D27.505.696.277.100.035.060', 'D27.505.954.427.210.100.035.060'], ['B01.050'], ['D02.355.417.166', 'D02.355.601.325', 'D02.455.526.510.213'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.355.601.570'], ['F02.463.425.874.500'], ['C10.597.606.525', 'C23.888.592... | ['Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The quantitative relations between diffusion-controlled reaction rate and characteristic parameters in enzyme-substrate reactions systems. II. Charged substrates. | The quantitative relationship between the spatial factor and the force-range factor on the one hand and the ionic strength and the charges of reactants on the other has been calculated for non-spherically symmetric reaction systems. New upper limits of combination reactions between enzymes and charged substrates have b... | ['Binding Sites', 'Diffusion', 'Enzymes', 'Fumarates', 'Glyceraldehyde-3-Phosphate Dehydrogenases', 'Kinetics', 'Models, Chemical', 'Osmolar Concentration'] | 1,198,092 | [['G02.111.570.120'], ['G01.202', 'G02.196'], ['D08.811'], ['D02.241.081.337.302'], ['D08.811.682.657.163.750'], ['G01.374.661', 'G02.111.490'], ['E05.599.495'], ['G02.640']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vivo association of Actinobacillus pleuropneumoniae serotype 2 with the respiratory epithelium of pigs. | The ability of an Actinobacillus pleuropneumoniae serotype 2 strain to associate in vivo with the epithelium of the porcine respiratory tract was investigated in a sequential study after intranasal inoculation of hysterectomy-derived and colostrum-deprived pigs. At 30 min postinoculation more than 95% of the bacteria p... | ['Actinobacillus pleuropneumoniae', 'Animals', 'Bacterial Adhesion', 'Bronchi', 'Epithelium', 'Fimbriae, Bacterial', 'Lung', 'Respiratory System', 'Serotyping', 'Swine', 'Trachea'] | 7,907,578 | [['B03.440.450.009.580', 'B03.660.250.550.050.580'], ['B01.050'], ['G06.099.050'], ['A04.411.125'], ['A10.272'], ['A11.284.180.285', 'A20.843'], ['A04.411'], ['A04'], ['E01.370.225.812.742', 'E01.370.225.875.150.125.890', 'E05.200.812.742', 'E05.200.875.150.125.890', 'E05.478.594.780'], ['B01.050.150.900.649.313.500.88... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Religious Coping and Glycemic Control in Couples with Type 2 Diabetes. | This study examines the role of religious coping in couples' diabetes management processes. Eighty-seven couples where one spouse had type 2 diabetes were surveyed. The relationships between religious coping (positive and negative), shared glycemic control activities (e.g., planning a healthy diet), and glycemic contro... | ['Adaptation, Psychological', 'Adult', 'Aged', 'Diabetes Mellitus, Type 2', 'Diet, Healthy', 'Female', 'Health Behavior', 'Humans', 'Male', 'Middle Aged', 'Religion and Psychology', 'Spouses'] | 28,589,560 | [['F01.058'], ['M01.060.116'], ['M01.060.116.100'], ['C18.452.394.750.149', 'C19.246.300'], ['F01.829.458.205.500', 'G07.203.650.240.629'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.880', 'K01.844.664'], ['F01.829.263.500.660', 'I01.880.853.150.500.670', 'M01.816']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Humanities [K]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Hydrodynamic properties of the chromaffin granule hydrogen ion pumping adenosinetriphosphatase. | We have determined the hydrodynamic properties of detergent-solubilized ATPase, which is coupled to H+ pumping in bovine adrenal chromaffin granules, by sedimentation equilibrium centrifugation and gel permeation chromatography. The protein solubilized with detergent containing phosphatidylserine sediments as a particl... | ['Adrenal Medulla', 'Animals', 'Cattle', 'Chromaffin Granules', 'Chromaffin System', 'Intracellular Membranes', 'Kinetics', 'Protein Conformation', 'Proton-Translocating ATPases'] | 2,887,199 | [['A06.300.071.265'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A06.224.161.500', 'A11.284.430.214.190.500.207', 'A11.284.430.214.190.875.190.190.207'], ['A06.224'], ['A11.284.149.450', 'A11.284.835.514'], ['G01.374.661', 'G02.111.490'], ['G02.111.570.820.709'], ['D08.811.277.040.025.325', 'D08.811.913.69... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Altered bone mass and turnover in female patients with adrenal incidentaloma: the effect of subclinical hypercortisolism. | The strategy of treatment for patients with adrenal incidentalomas (AI) may depend upon the presence of hormonal hypersecretion. Although alterations of bone turnover have been recently reported, data on bone mineral density (BMD) are not available in AI patients. We evaluated bone turnover and BMD in 32 female AI pati... | ['Adrenal Gland Neoplasms', 'Adult', 'Aged', 'Amino Acids', 'Bone Density', 'Bone Remodeling', 'Collagen', 'Collagen Type I', 'Creatinine', 'Female', 'Femur', 'Humans', 'Hydrocortisone', 'Middle Aged', 'Osteocalcin', 'Peptides', 'Spine'] | 10,404,807 | [['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['M01.060.116'], ['M01.060.116.100'], ['D12.125'], ['G11.427.100'], ['G11.427.213', 'G16.762.150'], ['D05.750.078.280', 'D12.776.860.300.250'], ['D05.750.078.280.300.100', 'D12.776.860.300.250.300.100'], ['D03.383.129.308.207'], ['A02.835.232.043.150'], ['B01.050.150.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mathematical models to predict kinetic behavior and growth probabilities of Listeria monocytogenes on pork skin at constant and dynamic temperatures. | In this study, mathematical models were developed to predict the growth probability and kinetic behavior of Listeria monocytogenes on fresh pork skin during storage at different temperatures. A 10-strain mixture of L. monocytogenes was inoculated on fresh pork skin (3 by 5 cm) at 4 log CFU/cm(2). The inoculated samples... | ['Animals', 'Colony Count, Microbial', 'Food Microbiology', 'Humans', 'Kinetics', 'Listeria monocytogenes', 'Mathematics', 'Meat', 'Models, Biological', 'Probability', 'Swine', 'Temperature'] | 24,215,689 | [['B01.050'], ['E01.370.225.875.220', 'E05.200.875.220'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['B03.353.500.500.500', 'B03.510.100.500.500', '... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Assistive obstacle detection and navigation devices for vision-impaired users. | Quality of life for the visually impaired is an urgent worldwide issue that needs to be addressed. Obstacle detection is one of the most important navigation tasks for the visually impaired. In this research, a novel range sensor placement scheme is proposed in this paper for the development of obstacle detection devic... | ['Canes', 'Equipment Design', 'Humans', 'Infrared Rays', 'Self-Help Devices', 'Sensory Aids', 'Shoes', 'Visually Impaired Persons'] | 23,350,879 | [['E07.858.442.250'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650.552', 'G01.590.540.552', 'G01.750.250.650.552', 'G01.750.770.578.552', 'G16.500.275.063.725.525.400', 'G16.500.750.775.525.400', 'N06.230.300.100.725.525.400'], ['E07.796'], ['E07.814'], ['J01.637.215.800'], ['M01.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
DNA replication defects delay cell division and disrupt cell polarity in early Caenorhabditis elegans embryos. | In early Caenorhabditis elegans embryos, asymmetric cell divisions produce descendants with asynchronous cell cycle times. To investigate the relationship between cell cycle regulation and pattern formation, we have identified a collection of embryonic-lethal mutants in which cell divisions are delayed and cell fate pa... | ['Amino Acid Sequence', 'Animals', 'Body Patterning', 'Caenorhabditis elegans', 'Caenorhabditis elegans Proteins', 'Cell Cycle', 'Cell Division', 'Cell Polarity', 'Chromosome Mapping', 'DNA Primase', 'DNA Replication', 'DNA-Binding Proteins', 'Embryo, Nonmammalian', 'Endoderm', 'Genetic Linkage', 'Helminth Proteins', '... | 11,112,326 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G07.345.500.100'], ['B01.050.500.500.294.400.875.660.250.250'], ['D12.776.419.500'], ['G04.144'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.250'], ['E05.393.183'], ['D08.811.913.696.445.735.270.375'], ['G02.111.225', 'G05.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Mortality in acute non-invasive ventilation. | A prospective study of non-invasive ventilation at The Prince Charles Hospital outside of the intensive care unit from March 2015 to March 2016 was performed. Overall 69 patients were included. Acute hypercapnic respiratory failure was the most common indication (n = 59; 85%). 49 (71%) had multifactorial respiratory fa... | ['Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mortality', 'Noninvasive Ventilation', 'Prospective Studies', 'Respiratory Insufficiency', 'Treatment Outcome'] | 29,224,200 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.550', 'N06.850.520.308.985.550'], ['E02.041.625.591', 'E02.880.820.657'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.8... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Conebulization of surfactant and urokinase restores gas exchange in perfused lungs with alveolar fibrin formation. | Alveolar fibrin generation has been suggested to possess strong surfactant-inhibitory potency. In perfused rabbit lungs, fibrin formation in the alveolar space was induced by sequential ultrasonic aerosolization of fibrinogen and thrombin, and the efficacy of rescue administration of surfactant and urokinase was invest... | ['Animals', 'Bronchoalveolar Lavage Fluid', 'Drug Synergism', 'Fibrin', 'Fibrin Fibrinogen Degradation Products', 'Fibrinogen', 'In Vitro Techniques', 'Lung', 'Nebulizers and Vaporizers', 'Perfusion', 'Pulmonary Alveoli', 'Pulmonary Gas Exchange', 'Pulmonary Surfactants', 'Rabbits', 'Sodium Chloride', 'Urokinase-Type P... | 11,238,021 | [['B01.050'], ['E05.927.100.500'], ['G07.690.773.968.477'], ['D12.776.124.270'], ['D12.776.124.270.300', 'D12.776.811.300.290'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['E05.481'], ['A04.411'], ['E07.605'], ['E05.680'], ['A04.411.715'], ['E01.370.386.700.650', 'G03.143.775.602... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of timing and graft dysfunction on survival and cardiac allograft vasculopathy in antibody-mediated rejection. | BACKGROUND: Antibody-mediated rejection (AMR) has been associated with increased death and cardiac allograft vasculopathy (CAV). Early studies suggested that late AMR was rarely associated with graft dysfunction, whereas recent reports have demonstrated an association with increased mortality. We investigated the timin... | ['Allografts', 'Antibodies', 'Graft Rejection', 'Graft Survival', 'Heart Transplantation', 'Humans', 'Retrospective Studies'] | 27,423,693 | [['A01.941.500'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['G12.875.545.328'], ['G12.875.545.340'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.3... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
In Vitro Activity of Cefiderocol, a Siderophore Cephalosporin, Against Gram-Negative Bacilli Isolated by Clinical Laboratories in North America and Europe in 2015-2016: SIDERO-WT-2015. | Cefiderocol (S-649266) is a parenteral siderophore cephalosporin in phase III of clinical development. In this study, we determined the in vitro susceptibility to cefiderocol and comparators of a 2015-2016 collection of 8954 clinical isolates of Gram-negative bacilli (GNB), provided by 100 clinical laboratories in Nort... | ['Acinetobacter', 'Anti-Bacterial Agents', 'Burkholderia cepacia', 'Cephalosporins', 'Drug Resistance, Multiple, Bacterial', 'Europe', 'Gram-Negative Bacteria', 'Gram-Negative Bacterial Infections', 'Humans', 'Microbial Sensitivity Tests', 'North America', 'Pseudomonas aeruginosa', 'Siderophores', 'Stenotrophomonas mal... | 30,471,402 | [['B03.440.400.425.537.050', 'B03.660.250.530.050'], ['D27.505.954.122.085'], ['B03.660.075.090.688.100.110.500'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.300.249'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['Z01.542'], ['B03.440'], ['C01.150.252.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Why Taranaki women choose to have a mastectomy when suitable for breast conservation treatment. | BACKGROUND: Breast conservation treatment (BCT) rate is recognized as a marker of surgical practice. An historically low BCT rate may reflect the requirement for Taranaki women to travel for adjuvant radiotherapy. The aim of this study was to determine the reasons Taranaki women with breast cancer choose mastectomy or ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Choice Behavior', 'Female', 'Humans', 'Mastectomy', 'Mastectomy, Segmental', 'Middle Aged', 'Neoplasm Recurrence, Local', 'New Zealand', 'Radiotherapy'] | 19,895,515 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['F02.463.785.373.346'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.466'], ['E04.466.701'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['Z01.639.760.747', 'Z01.678.100.747'], ['E02.815']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Electrical stimulation of retinal ganglion cells with diamond and the development of an all diamond retinal prosthesis. | Electronic retinal implants for the blind are already a market reality. A world wide effort is underway to find the technology that offers the best combination of performance and safety for potential patients. Our approach is to construct an epi-retinally targeted device entirely encapsulated in diamond to maximise lon... | ['Animals', 'Cells, Cultured', 'Crystallization', 'Diamond', 'Electric Stimulation', 'Electrodes, Implanted', 'Equipment Design', 'Evoked Potentials, Visual', 'Humans', 'Microelectrodes', 'Rats', 'Retinal Ganglion Cells', 'Visual Prosthesis'] | 22,613,134 | [['B01.050'], ['A11.251'], ['E05.196.300', 'G02.171'], ['D01.268.150.200'], ['E05.723.402'], ['E07.305.250.319', 'E07.695.202'], ['E05.320'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.305.250.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['A0... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of histidine-proline-rich glycoprotein on plasminogen activation in solution and on surfaces. | Histidine-proline-rich glycoprotein (HPRG) has long been known to associate with plasminogen (Plg) in solution, but the consequences of this interaction have not been defined. Here we show that HPRG adsorbed to a glycosaminoglycan (GAG) surface also binds Plg with a Kd value of 0.7 micromol/l. Moreover, we present evid... | ['Adsorption', 'Catalysis', 'Glycoproteins', 'Glycosaminoglycans', 'Histidine', 'Humans', 'Peptide Fragments', 'Plasminogen', 'Proline', 'Protein Binding', 'Solutions', 'Surface Properties', 'Tissue Plasminogen Activator'] | 15,613,921 | [['G01.030', 'G02.020'], ['G02.130'], ['D09.400.430', 'D12.776.395'], ['D09.698.373'], ['D12.125.072.329', 'D12.125.142.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.541'], ['D08.622.610', 'D12.776.124.790.223.580', 'D12.776.377.715.182.580', 'D12.776.811.243.610'], ['D12.125.072.401.623'], ['G02.11... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Morphology-Dependent Catalytic Activity of Ru/CeO₂ in Dry Reforming of Methane. | Three morphology-controlled CeO₂, namely nanorods (NRs), nanocubes (NCs), and nanopolyhedra (NPs), with different mainly exposed crystal facets of (110), (100), and (111), respectively, have been used as supports to prepare Ru (3 wt.%) nanoparticle-loaded catalysts. The catalysts were characterized by H₂-temperature pr... | ['Adsorption', 'Carbon Dioxide', 'Catalysis', 'Cerium', 'Chemistry Techniques, Synthetic', 'Hydrogen', 'Methane', 'Nanoparticles', 'Oxidation-Reduction', 'Oxygen', 'Ruthenium'] | 30,717,097 | [['G01.030', 'G02.020'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['G02.130'], ['D01.268.558.362.249', 'D01.552.550.399.249'], ['E05.197', 'J01.897.836.249'], ['D01.268.406', 'D01.362.340'], ['D02.455.326.146.571'], ['J01.637.512.600'], ['G02.700', 'G03.295.531'], ['D01.268.185.550', 'D01.362.670'], ['D01.268... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Thenoyltrifluoracetone induces lipid peroxidation in rat liver mitochondria. | Addition of thenoyltrifluoracetone to mitochondria oxidizing NAD-dependent substrates induced lipid peroxidation and uncoupling of oxidative phosphorylation. Butylated hydroxytoluene, an antioxidant, prevented accumulation of lipid peroxidation products but failed to prevent deenergization of the mitochondria. | ['Adenosine Diphosphate', 'Animals', 'Butylated Hydroxytoluene', 'Carbonyl Cyanide m-Chlorophenyl Hydrazone', 'Kinetics', 'Lipid Peroxidation', 'Mitochondria, Liver', 'Oxygen Consumption', 'Rats', 'Thenoyltrifluoroacetone', 'Thiobarbituric Acid Reactive Substances'] | 8,224,786 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['B01.050'], ['D02.455.426.559.389.657.239.216'], ['D02.442.288.200', 'D02.626.260'], ['G01.374.661', 'G02.111.490'], ['G02.111.515', 'G03.295.531.587'], ['A11.284.430.214.190.875.564.461', 'A11.284.835.626.461'], ['G03.680'], ['B01.050.150... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Commercial intermediate pressure MALDI ion mobility spectrometry mass spectrometer capable of producing highly charged laserspray ionization ions. | The first examples of highly charged ions observed under intermediate pressure (IP) vacuum conditions are reported using laser ablation of matrix/analyte mixtures. The method and results are similar to those obtained at atmospheric pressure (AP) using laserspray ionization (LSI) and/or matrix assisted inlet ionization ... | ['Spectrometry, Mass, Electrospray Ionization', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization', 'Tandem Mass Spectrometry'] | 21,166,462 | [['E05.196.566.600'], ['E05.196.566.755'], ['E05.196.566.880']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dual cigarette and e-cigarette use in cancer survivors: an analysis using Population Assessment of Tobacco Health (PATH) data. | PURPOSE: Cancer survivors who smoke cigarettes face health risks from continued smoking. Some smokers use e-cigarettes to reduce combustible cigarette use, but research on whether cancer survivors do the same is limited. Research is needed to understand whether smokers who are cancer survivors use e-cigarettes at highe... | ['Cancer Survivors', 'Cross-Sectional Studies', 'Electronic Nicotine Delivery Systems', 'Female', 'Humans', 'Male', 'Middle Aged', 'Smoking', 'Tobacco Products'] | 30,675,695 | [['M01.860.350'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['J01.637.767.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.145.805'], ['J01.637.767.844']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Simultaneous prediction of hyperglycemia and dyslipidemia in school children in Santa Catarina State, Brazil based on waist circumference measurement. | OBJECTIVES: Waist circumference (WC) is highly associated with metabolic risk factor clusters (RFC) for chronic non-communicable diseases (NCDs). In this study, we evaluated the use of WC measurements to detect hyperglycemia and dyslipidemia in children and adolescents using the WC cutoff points reported in the Bogalus... | ['Adolescent', 'Brazil', 'Child', 'Cholesterol', 'Cholesterol, LDL', 'Dyslipidemias', 'Female', 'Humans', 'Hyperglycemia', 'Logistic Models', 'Male', 'Predictive Value of Tests', 'Triglycerides', 'Waist Circumference'] | 24,012,695 | [['M01.060.057'], ['Z01.107.757.176'], ['M01.060.406'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['C18.452.584.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.952'], ... | ['Named Groups [M]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Instability and rotation of silver silicone penile prosthesis. | Four cases of a similar complication in patients who have had the Jonas silver silicone prosthesis implanted are reported. The patients complain of instability and rotation of the prosthesis to a position that stands out from the body, no matter what the initial position of the prosthesis. The rotation causes difficult... | ['Adult', 'Aged', 'Humans', 'Male', 'Middle Aged', 'Penis', 'Prostheses and Implants', 'Prosthesis Failure', 'Silicones', 'Silver'] | 3,341,095 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A05.360.444.492'], ['E07.695'], ['C23.550.767.865', 'E05.325.771'], ['D02.756.650.700', 'D05.750.900.850', 'D25.720.900.850', 'J01.637.051.720.900.850'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.544.812... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Genetic predisposition in anti-LGI1 and anti-NMDA receptor encephalitis. | We performed a genome-wide association study in 1,194 controls and 150 patients with anti-N-methyl-D-aspartate receptor (anti-NMDAR, n = 96) or anti-leucine-rich glioma-inactivated1 (anti-LGI1, n = 54) autoimmune encephalitis. Anti-LGI1 encephalitis was highly associated with 27 single-nucleotide polymorphisms (SNPs) i... | ['Adolescent', 'Adult', 'Aged', 'Autoantibodies', 'Encephalitis', 'Female', 'Genetic Predisposition to Disease', 'Genome-Wide Association Study', 'Hashimoto Disease', 'Humans', 'Intracellular Signaling Peptides and Proteins', 'Male', 'Middle Aged', 'Polymorphism, Single Nucleotide', 'Protein-Serine-Threonine Kinases', ... | 29,572,931 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['C10.228.140.430'], ['C23.550.291.687.500', 'G05.380.355'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Emotional support, conflict, depression, and relationship satisfaction in a romantic partner. | One aim of this study was to determine the relative contribution of partner conflict and support to satisfaction with a romantic relationship when conflict and support are measured in terms of the same characteristics. Another aim was to ascertain whether support is indirectly associated with relationship satisfaction ... | ['Adult', 'Conflict, Psychological', 'Courtship', 'Cross-Sectional Studies', 'Depression', 'Female', 'Humans', 'Interpersonal Relations', 'Male', 'Models, Psychological', 'Personal Satisfaction', 'Social Support', 'United Kingdom'] | 15,612,609 | [['M01.060.116'], ['F01.658.209'], ['F01.145.802.279'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['E05.599.695'], ['F01.145.677'], ['I01.880.853.500.600'], ['Z01.542.363']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Variable length chloroplast markers for population genetic studies in Acmispon (Fabaceae). | PREMISE OF THE STUDY: To estimate genetic structure, chloroplast loci containing length-variable regions were developed for two legumes, Acmispon argophyllus and A. dendroideus. •METHODS AND RESULTS: Primers for 14 chloroplast loci containing repeat regions were developed from the chloroplast genome sequence of the leg... | ['Alleles', 'Chloroplasts', 'Colorado', 'Fabaceae', 'Genetic Loci', 'Genetic Markers', 'Genetics, Population', 'Polymorphism, Genetic'] | 23,002,164 | [['G05.360.340.024.340.030'], ['A11.284.430.214.190.875.700.140'], ['Z01.107.567.875.760.210'], ['B01.650.940.800.575.912.250.401'], ['G05.360.340.024.380'], ['D23.101.387', 'G05.695.450'], ['H01.158.273.343.335'], ['G05.365.795']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Growth and fresh meat quality characteristics of pigs supplemented with vitamin E. | Crossbred pigs (n = 30) were fed to determine the influence of supplementation with vitamin E on growth and slaughter characteristics of swine and on the quality characteristics of fresh pork. Pigs received either a control diet containing no vitamin E (CON) or a diet formulated to contain 100 mg of vitamin E/kg feed (... | ['Analysis of Variance', 'Animals', 'Body Composition', 'Diet', 'Dose-Response Relationship, Drug', 'Eating', 'Female', 'Food Technology', 'Food, Fortified', 'Lipid Metabolism', 'Lipids', 'Male', 'Meat', 'Muscle, Skeletal', 'Oxidation-Reduction', 'Random Allocation', 'Swine', 'Vitamin E', 'Weight Gain'] | 8,778,117 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['G07.203.650.240'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.203.650.283', 'G10.261.330'], ['J01.576.423.850'], ['G07.203.300.515', 'J02.500.515'], ['G03.458'], ['D10'], ['G07.203.300.600', ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Delirium recognition by family: European Portuguese validation study of the family confusion assessment method. | OBJECTIVES: To present the validation study of the European Portuguese version of the Family Confusion Assessment Method (FAM-CAM) and to assess the level of psychological distress in families and caregivers of elderly hospitalized adults with delirium.DESIGN: Validation study.SETTING: Intermediate care unit of the Int... | ['Aged', 'Aged, 80 and over', 'Caregivers', 'Delirium', 'Family', 'Female', 'Hospitalization', 'Humans', 'Language', 'Male', 'Neuropsychological Tests', 'Portugal', 'Psychiatric Status Rating Scales', 'Sensitivity and Specificity', 'Stress, Psychological'] | 25,039,562 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['C10.597.606.337.500', 'C23.888.592.604.339.500', 'F01.700.250.500', 'F03.615.350'], ['F01.829.263', 'I01.880.853.150'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399',... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Cloning and expression of a deoxyribonucleic acid fragment that encodes for the adhesive antigen K99. | Deoxyribonucleic acid fragments of the naturally occurring conjugative K99 plasmid were cloned into vectors pBR322 and pBR325. The smallest deoxyribonucleic acid segment obtained that still expressed K99 was 4.5 megadaltons in size. With regard to the serological, adhesive, and morphological properties, no differences ... | ['Animals', 'Antigens, Bacterial', 'Clone Cells', 'DNA', 'DNA Restriction Enzymes', 'Drug Resistance, Microbial', 'Epitopes', 'Escherichia coli', 'Genetic Code', 'Mutation', 'Plasmids', 'Rabbits', 'Streptomycin', 'Tetracycline'] | 6,159,326 | [['B01.050'], ['D23.050.161'], ['A11.251.353'], ['D13.444.308'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['G06.225', 'G07.690.773.984.269'], ['D23.050.550'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.335'], ['G05.365.590'], ['G05.360.600'], ['B01.050.15... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mutational spectrum of the p53 gene in human small-cell lung cancer and relationship to clinicopathological data. | The spectrum of p53 gene mutations was determined in formalin-fixed, paraffin-embedded samples of small-cell lung cancer derived from 28 patients. By direct sequencing of exons 5, 7, and 8, including their flanking intron sequences, 18 mutations were identified in 17 tumors (61%), and in all but two of these the wild t... | ['Base Sequence', 'Carcinoma, Small Cell', 'Genes', 'Humans', 'Lung Neoplasms', 'Molecular Probes', 'Molecular Sequence Data', 'Point Mutation', 'Tumor Suppressor Protein p53'] | 8,384,408 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.557.470.200.380'], ['G05.360.340.024.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['D27.505.259.750', 'D27.720.470.530'], ['L01.453.245.667'], ['G05.365.590.675'], ['D12.776.157.687.650', ... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Development and validation of systems for rational use of viral load testing in adults receiving first-line ART in sub-Saharan Africa. | BACKGROUND: World Health Organization (WHO) immunological and clinical criteria for monitoring first-line antiretroviral treatment (ART) offer low accuracy for predicting viral failure. Targeting viral load assays to those at high risk has been recommended and a system to do this has been developed in Cambodia. Systems... | ['Adult', 'Algorithms', 'Anti-Retroviral Agents', 'CD4 Lymphocyte Count', 'Cambodia', 'Drug Therapy, Combination', 'Female', 'HIV Infections', 'Humans', 'Male', 'Prognosis', 'Sensitivity and Specificity', 'Treatment Failure', 'Uganda', 'Viral Load', 'World Health Organization'] | 21,673,555 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['D27.505.954.122.388.077'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.500.150', 'G04.140.107.595.500.150', 'G09.188.105.595.500.150'], ['Z01.252.145.182'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Studies of protein interactions by biosensor technology: an alternative approach to the analysis of sensorgrams deviating from pseudo-first-order kinetic behavior. | A procedure for evaluating the thermodynamic equilibrium constant by kinetic analysis of sensorgrams which deviate from the pseudo-first-order kinetic behavior predicted for 1:1 interactions between ligate and affinity sites on the sensor surface is described. This analysis employs quantitative expressions that are use... | ['Antibodies, Monoclonal', 'Antigen-Antibody Reactions', 'Biosensing Techniques', 'Immunoglobulin Fab Fragments', 'Kinetics', 'Paraquat', 'Proteins', 'Thermodynamics'] | 9,025,919 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.122'], ['E05.601.043'], ['D12.644.541.500.650', 'D12.776.124.486.485.680.650', 'D12.776.124.790.651.680.650', 'D12.776.377.715.548.680.650'], ['G01.374.661', 'G02.111.490'], ['D03.383.725.762.621'], ['D12.776'], ['G01.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Measuring changes in the optic nerve sheath diameter in patients with idiopathic normal-pressure hydrocephalus: a useful diagnostic supplement to spinal tap tests. | BACKGROUND AND PURPOSE: Cerebrospinal fluid (CSF) removal improves clinical symptoms of many patients with idiopathic normal-pressure hydrocephalus (iNPH). The aim of this study was to investigate the correlation of changes in the optic nerve sheath diameter (ONSD) with patient responses to CSF removal.METHODS: Transor... | ['Aged', 'Aged, 80 and over', 'Female', 'Healthy Volunteers', 'Humans', 'Hydrocephalus, Normal Pressure', 'Male', 'Middle Aged', 'Observer Variation', 'Optic Nerve', 'Orbit', 'Posture', 'Predictive Value of Tests', 'Spinal Puncture', 'Supine Position', 'Treatment Outcome', 'Ultrasonography'] | 27,981,690 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.774.500', 'M01.955.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.602.750'], ['M01.060.116.630'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['A08.800.800.120.680'], ['A02.835.232.781.324.690'], ['G11.427.... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Biochemical studies on a cell surface determinant involved in T-cell proliferation. | Previous studies have shown that a monoclonal antibody (TH5.2) recognizes a cell-surface determinant which is involved in the proliferative capability of T cells. The work reported here demonstrates that the T-cell-surface antigen recognized by TH5.2 is a glycoprotein of 55,000 to 60,000 molecular weight. The molecule ... | ['Antibodies, Monoclonal', 'Antigens, Surface', 'Cell Line', 'Glycoproteins', 'Humans', 'Membrane Proteins', 'Molecular Weight', 'Protein Processing, Post-Translational', 'T-Lymphocytes', 'Tunicamycin'] | 3,496,975 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301'], ['A11.251.210'], ['D09.400.430', 'D12.776.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543'], ['G02.494'], ['G02.111.660.871.790.600', 'G02.111.691.600', 'G03.734.871.790.600', 'G05.308.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gender, social class and illness among young people. | Gender and social class differences in illness among young people have been a neglected area in research on social inequities in health. It has been assumed that the illness differentials among adults persist throughout their lives. Only recently have social class health differentials among young people become a topic ... | ['Adolescent', 'Adult', 'Age Factors', 'Chronic Disease', 'Educational Status', 'Employment', 'Female', 'Finland', 'Humans', 'Logistic Models', 'Male', 'Marriage', 'Occupations', 'Poverty', 'Prevalence', 'Residence Characteristics', 'Sex Factors', 'Social Class'] | 1,574,732 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['C23.550.291.500'], ['N01.824.196'], ['N01.824.245'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', ... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Racial Differences in the Influence of Interpregnancy Interval on Fetal Growth. | Objectives Assess the influence of maternal race on the association between interpregnancy interval (IPI) and risk of small for gestational age (SGA) and large for gestational age (LGA) births. Methods Statewide population-based cohort study of 380,520 singleton births. We calculated risk of SGA and LGA births followin... | ['Adult', 'Birth Intervals', 'Birth Weight', 'Child, Preschool', 'Cohort Studies', 'Continental Population Groups', 'Educational Status', 'Female', 'Fetal Development', 'Gestational Age', 'Humans', 'Infant', 'Ohio', 'Pregnancy', 'Prenatal Care', 'Retrospective Studies'] | 27,475,828 | [['M01.060.116'], ['I01.240.361.150', 'N01.224.361.150'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['M01.060.406.448'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['M01.686.508'], ['N01.82... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Adrenergic responses of asthmatic and normal subjects to submaximal and maximal work levels. | The response of the adrenergic system of asthmatic subjects to exercise and the role of plasma catecholamines in exercise-induced asthma were investigated. Plasma levels of norepinephrine and epinephrine were measured at rest, during and after exercise in 7 asthmatic and 9 matched normal subjects. Exercise-induced bron... | ['Adrenergic Fibers', 'Adult', 'Asthma', 'Catecholamines', 'Humans', 'Male', 'Physical Exertion'] | 618,943 | [['A08.675.100.500', 'A08.675.542.075', 'A11.671.501.075'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.683']] | ['Anatomy [A]', 'Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Increased mortality associated with elevated carcinoembryonic antigen in insurance applicants. | OBJECTIVE: Determine the relationship between the carcinoembryonic antigen (CEA) value and all-cause mortality in life insurance applicants aged 50 years and over.METHOD: By use of the Social Security Master Death Index, mortality was examined in 115,590 insurance applicants aged 50 and up for whom blood samples for CE... | ['Aged', 'Carcinoembryonic Antigen', 'Female', 'Humans', 'Insurance, Life', 'Male', 'Middle Aged', 'Mortality'] | 18,522,142 | [['M01.060.116.100'], ['D12.776.395.550.200.210', 'D12.776.543.550.200.210', 'D23.050.285.329', 'D23.050.301.350.210', 'D23.101.140.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.543'], ['M01.060.116.630'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.550', 'N06.850.520.308... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Social factors influencing hospital arrival time in acute ischemic stroke patients. | INTRODUCTION: This is a multi-center, hospital-based study aiming to estimate social factors influencing pre-hospital times of arrival in acute ischemic stroke, with a perspective of finding ways to reduce arrival time and to augment the number of patients eligible for intra-arterial thrombolysis.METHODS: Acute ischemi... | ['Brain Ischemia', 'Chi-Square Distribution', 'Emergency Medical Services', 'Emergency Service, Hospital', 'Female', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Neuroimaging', 'Patient Admission', 'Risk Factors', 'Socioeconomic Factors', 'Statistics, Nonparametric', 'Stroke', 'Thrombolytic Therapy', 'Time Fact... | 21,562,749 | [['C10.228.140.300.150', 'C14.907.253.092'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['N02.421.297'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Adaptation of protein metabolism to endurance training. Increased amino acid oxidation in response to training. | This study was conducted to investigate alterations in excretion of urea and total nitrogen after6-8 weeks of daily exercise and to establish if the capacity for amino acid oxidation in muscle is influenced by endurance training. Urea nitrogen excretion was increased in trained compared with untrained rats and nitrogen... | ['Adaptation, Physiological', 'Amino Acids', 'Animals', 'Leucine', 'Male', 'Muscles', 'Nitrogen', 'Oxidation-Reduction', 'Physical Exertion', 'Rats', 'Transaminases', 'Urea'] | 883,961 | [['G07.025', 'G16.012.500'], ['D12.125'], ['B01.050'], ['D12.125.070.637', 'D12.125.142.441'], ['A02.633', 'A10.690'], ['D01.268.604', 'D01.362.625'], ['G02.700', 'G03.295.531'], ['G11.427.683'], ['B01.050.150.900.649.313.992.635.505.700'], ['D08.811.913.477.700'], ['D02.065.950']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Studies of X-ray-induced chromosome aberrations in cells of the black-tailed wallaby. I. Non-random exchange in peripheral blood cells irradiated in Go. | The distribution of exchanges between individual chromosome arms in mitotic peripheral blood cells following X-irradiation in Go has been measured. It was found that, although all arms exchanged with each other, there were small but significant departures from the frequencies expected on the basis of random breakage an... | ['Animals', 'Cells, Cultured', 'Chromosome Aberrations', 'Chromosomes', 'Interphase', 'Karyotyping', 'Lymphocytes', 'Macropodidae', 'Marsupialia', 'X-Rays'] | 440,320 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The RPAP3-Cterminal domain identifies R2TP-like quaternary chaperones. | R2TP is an HSP90 co-chaperone that assembles important macro-molecular machineries. It is composed of an RPAP3-PIH1D1 heterodimer, which binds the two essential AAA+ATPases RUVBL1/RUVBL2. Here, we resolve the structure of the conserved C-terminal domain of RPAP3, and we show that it directly binds RUVBL1/RUVBL2 hexamer... | ['ATPases Associated with Diverse Cellular Activities', 'Adaptor Proteins, Signal Transducing', 'Antigens, Surface', 'Apoptosis Regulatory Proteins', 'Carrier Proteins', 'Cell Line', 'DNA Helicases', 'GTP-Binding Proteins', 'HEK293 Cells', 'HSP90 Heat-Shock Proteins', 'HeLa Cells', 'Humans', 'Male', 'Membrane Proteins'... | 29,844,425 | [['D08.811.277.040.013.500', 'D08.811.277.040.025.024', 'D12.776.157.025.750'], ['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['D23.050.301'], ['D12.644.360.075', 'D12.776.476.075'], ['D12.776.157'], ['A11.251.210'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['D08.811.277.040.330.300', 'D12.776.157.3... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Respiratory function of hyoid muscles and hyoid arch. | The position of the hyoid arch suggests that it supports soft tissue surrounding the upper airway (UA) and can act to maintain UA patency. We also suspected that muscles inserting on the hyoid arch might show respiratory patterns of activity that could be affected by respiratory stimuli. To test these possibilities, we... | ['Airway Resistance', 'Animals', 'Dogs', 'Electric Stimulation', 'Hyoid Bone', 'Inspiratory Capacity', 'Muscles', 'Respiration', 'Thyroid Cartilage', 'Tidal Volume', 'Traction', 'Vagotomy'] | 6,469,781 | [['E01.370.386.700.050', 'G09.772.060'], ['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.723.402'], ['A02.835.232.409'], ['E01.370.386.700.485.750.900.350', 'G09.772.850.970.500'], ['A02.633', 'A10.690'], ['G09.772.705'], ['A02.165.257.625.870', 'A02.165.407.500.870', 'A04.329.591.870'], ['E01.370.386.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Hyaline membrane syndrome. Evaluation of sonographic criteria]. | BACKGROUND: In preterm infants with hyaline membrane disease an echo increase above the diaphragm can be demonstrated by parasagittal sonography of the lower thorax using the liver or spleen as an acoustic window.METHODS: In order to study the clinical practicability of this observation we made 145 investigations in 10... | ['Artifacts', 'Bronchopulmonary Dysplasia', 'Humans', 'Hyaline Membrane Disease', 'Image Interpretation, Computer-Assisted', 'Infant, Newborn', 'Pulmonary Surfactants', 'Pulmonary Ventilation', 'Ultrasonography'] | 1,470,189 | [['E05.047'], ['C08.381.520.750.500', 'C16.614.521.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.840.500.475', 'C08.618.840.500.475', 'C16.614.521.563.475'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['M01.060.703.520'], ['D27.505.954.796.600'], ['E01.370.386.700.660', 'G09.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Delayed referral to a nephrologist: outcomes among patients who survive at least one year on dialysis. | OBJECTIVE: To investigate whether late referral to a nephrologist of patients with chronic renal insufficiency influences the likelihood of both transplantation and mortality among those who survive at least one year on dialysis.DESIGN: Retrospective national cohort study, using data from the Australia and New Zealand ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Australia', 'Child', 'Child, Preschool', 'Comorbidity', 'Databases, Factual', 'Female', 'Humans', 'Infant', 'Kidney Failure, Chronic', 'Kidney Transplantation', 'Male', 'Middle Aged', 'New Zealand', 'Referral and Consultation', 'Renal Dialysis', 'Retrospective Studi... | 12,149,081 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.639.100', 'Z01.678.100.373'], ['M01.060.406'], ['M01.060.406.448'], ['N05.715.350.225', 'N06.850.490.687'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C12.7... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Automated fiducial marker detection for patient registration in image-guided neurosurgery. | OBJECTIVE: The registration of applied fiducial markers within the preoperative data is often left to the surgeon, who has to identify and tag the center of each marker. This is both time-consuming and a potential source of error. For this reason, the development of an automated procedure was desirable. In this study, ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Algorithms', 'Brain', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', 'Infant', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neuronavigation', 'Retrospective Studies'] | 14,708,754 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G17.035', 'L01.224.050'], ['A08.186.211'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.400', 'L01.224.308.410'], ['M01.060.703'], ['E01.370.350.825.500'], ['M01.06... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Mechanism of action of cholera toxin and the mobile receptor theory of hormone receptor-adenylate cyclase interactions. | Rat liver membrane adenylate cyclase (EC 4.6.1.1) that has been stimulated more than 10-fold by cholera toxin (choleragen) has a 3-fold greater sensitivity to stimulation by glucagon. Choleragen similarly increases the sensitivity of cyclase to other peptide (ACTH, vasoactive intestinal polypeptide) and nonpeptide (cat... | ['Adenylyl Cyclases', 'Adipose Tissue', 'Animals', 'Cell Membrane', 'Chromatography, Gel', 'Enzyme Activation', 'Gangliosides', 'Glucagon', 'Iodine Radioisotopes', 'Liver', 'Models, Biological', 'Rats', 'Receptors, Cell Surface', 'Toxins, Biological', 'Vibrio cholerae'] | 164,020 | [['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['A10.165.114'], ['B01.050'], ['A11.284.149'], ['E05.196.181.400.250'], ['G02.111.263', 'G03.328'], ['D09.400.410.420.025.475', 'D10.390.470.025.475', 'D10.570.877.360.025.475'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['D01.268.380.400.500... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vitro stimulation of metacyclogenesis in Leishmania braziliensis, L. donovani, L. major and L. mexicana. | Promastigotes of Leishmania braziliensis, L. donovani, L. major and L. mexicana recently derived from tissue amastigotes were cultured in Schneider's Drosophila medium supplemented with 20% (v/v) heat-inactivated foetal calf serum and 25 micrograms gentamicin sulfate/ml at pH 5.5. These cultures produced more metacycli... | ['Animals', 'Complement System Proteins', 'Cricetinae', 'Host-Parasite Interactions', 'Hydrogen-Ion Concentration', 'Leishmania', 'Leishmania braziliensis', 'Leishmania donovani', 'Leishmania major', 'Leishmania mexicana', 'Leishmaniasis, Cutaneous', 'Leishmaniasis, Visceral', 'Life Cycle Stages', 'Mice', 'Mice, Inbred... | 9,585,932 | [['B01.050'], ['D12.776.124.486.274'], ['B01.050.150.900.649.313.992.635.075.250'], ['G16.527.200.400'], ['G02.300'], ['B01.268.475.868.488'], ['B01.268.475.868.488.080'], ['B01.268.475.868.488.230'], ['B01.268.475.868.488.405'], ['B01.268.475.868.488.410'], ['C01.610.752.300.500.400', 'C01.610.858.560.400', 'C01.920.8... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of tree height on branch hydraulics, leaf structure and gas exchange in California redwoods. | We examined changes in branch hydraulic, leaf structure and gas exchange properties in coast redwood (Sequoia sempervirens) and giant sequoia (Sequoiadendron giganteum) trees of different sizes. Leaf-specific hydraulic conductivity (k(L)) increased with height in S. sempervirens but not in S. giganteum, while xylem cav... | ['Carbon Isotopes', 'Photosynthesis', 'Plant Leaves', 'Plant Stems', 'Plant Transpiration', 'Sequoia', 'Sequoiadendron', 'Trees', 'Water', 'Xylem'] | 19,210,642 | [['D01.268.150.075', 'D01.496.123'], ['G02.111.158.937', 'G02.111.669.700', 'G02.740.921', 'G03.191.937', 'G03.493.700', 'G03.800.700', 'G15.568'], ['A18.024.812'], ['A18.024.937'], ['G15.713'], ['B01.650.940.800.575.912.625.750.699'], ['B01.650.940.800.575.912.625.750.749'], ['B01.650.915'], ['D01.045.250.875', 'D01.2... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lactobacillus kimchii sp. nov., a new species from kimchi. | A bacteriocin-producing lactic acid bacterium, which was isolated from the Korean fermented-vegetable food kimchi, was subjected to a polyphasic taxonomic study using phenotypic characterization and phylogenetic and genetic methods. This organism (MT-1077T) has phenotypic properties that are consistent with the descrip... | ['Bacterial Typing Techniques', 'Bacteriocins', 'Base Composition', 'DNA, Bacterial', 'DNA, Ribosomal', 'Fatty Acids', 'Fermentation', 'Food Microbiology', 'Korea', 'Lactobacillus', 'Molecular Sequence Data', 'Phenotype', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA', 'Vegetables'] | 11,034,488 | [['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['D12.776.097.151', 'D12.776.543.695.110'], ['G02.111.080'], ['D13.444.308.212'], ['D13.444.308.475'], ['D10.251'], ['G02.111.158.249', 'G03.191.249'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 |
Synthesis, characterization, and application of cationic water-soluble oligofluorenes in DNA-hybridization detection. | A simple and efficient approach was developed for the synthesis of a series of cationic water-soluble oligofluorenes up to a chain length of a heptamer. Bromoalkyl-substituted fluorenyl boronic esters as the key intermediates were synthesized by using a modified Miyaura reaction. With an increasing number of repeat uni... | ['Cations', 'DNA', 'Fluorenes', 'Nucleic Acid Hybridization', 'Solubility', 'Water'] | 18,618,892 | [['D01.248.497.300'], ['D13.444.308'], ['D02.455.426.559.847.389', 'D04.615.389'], ['E05.393.661', 'G02.111.611'], ['G02.805'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Killer toxin production in Pichia acaciae is associated with linear DNA plasmids. | We have identified a strain of the yeast Pichia acaciae which produces a "killer" toxin active against the yeast Debaryomyces tamarii. The killer phenotype was associated with the presence of two DNA plasmids, pPacl-1 (13.6 kilobase pairs) and pPacl-2 (7.3 kilobase pairs). P. acaciae strains, cured of these plasmids by... | ['DNA, Fungal', 'Electrophoresis, Agar Gel', 'Killer Factors, Yeast', 'Phenotype', 'Pichia', 'Plasmids', 'Protein Biosynthesis', 'Proteins', 'Ultraviolet Rays'] | 2,245,477 | [['D13.444.308.300'], ['E05.196.401.153', 'E05.301.300.100'], ['D12.776.354.374', 'D23.946.587.531'], ['G05.695'], ['B01.300.107.795.700', 'B01.300.930.600'], ['G05.360.600'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['D12.776'], ['G01.358.500.505.650.891', 'G01.590.540.891', 'G01.750.250.650.891', 'G01.750.7... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
MRI-guided percutaneous transhepatic cholangiodrainage: feasibility study in a porcine model. | BACKGROUND AND STUDY AIMS: MRI-guided procedures combine high-quality imaging with lack of radiation. Percutaneous transhepatic cholangiodrainage under real-time MRI guidance (MRI-PTCD) seems promising, allowing targeted puncture and avoiding multiple blind passes and use of contrast, which are associated with standard... | ['Animals', 'Bile Ducts', 'Catheterization', 'Cholestasis', 'Drainage', 'Feasibility Studies', 'Female', 'Magnetic Resonance Imaging, Interventional', 'Surgery, Computer-Assisted', 'Swine'] | 24,694,300 | [['B01.050'], ['A03.159.183'], ['E02.148', 'E05.157'], ['C06.130.120.135'], ['E02.309', 'E04.237'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E04.502.515'], ['E04.749'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Modifying the glycosidic linkage in digitoxin analogs provides selective cytotoxins. | A chemoselective reaction between oxyamines and unprotected, unactivated reducing sugars was used to construct for the first time a panel of linkage-diversified neoglycosides. This panel of digitoxin analogs included potent and selective tumor cytotoxins; cytotoxicity was dependent on the structure of the glycosidic li... | ['Amines', 'Carbohydrates', 'Cytotoxins', 'Digitoxin', 'Glycoconjugates', 'Glycosylation'] | 18,240,383 | [['D02.092'], ['D09'], ['D27.888.569.213'], ['D04.210.500.155.580.130.500.336', 'D04.210.500.155.580.130.625', 'D09.408.180.261.336'], ['D09.400'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Medical and dermatology dictionaries: an examination of unstructured definitions and a proposal for the future. | Medical dictionaries serve to describe and clarify the term set used by medical professionals. In this commentary, we analyze a representative set of skin disease definitions from 2 prominent medical dictionaries, Stedman's Medical Dictionary and Dorland's Illustrated Medical Dictionary. We find that there is an appare... | ['Dermatology', 'Dictionaries, Medical as Topic', 'Forecasting', 'Terminology as Topic'] | 14,699,388 | [['H02.403.225'], ['L01.178.682.192.836.285.419', 'L01.178.682.192.836.842.385'], ['I01.320'], ['L01.559.598.400']] | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 |
Peripheral blood TIM-3 positive NK and CD8+ T cells throughout pregnancy: TIM-3/galectin-9 interaction and its possible role during pregnancy. | PROBLEM: The T-cell immunoglobulin and mucin domain (TIM) family is a relatively newly described group of molecules with a conserved structure and important immunological functions. Identification of Galectin-9 as a ligand for TIM-3 has established the Galectin-9/TIM-3 pathway as an important negative regulator of Th1 ... | ['Adult', 'CD56 Antigen', 'CD8-Positive T-Lymphocytes', 'Cytokines', 'Cytotoxicity, Immunologic', 'Down-Regulation', 'Female', 'Galectins', 'Hepatitis A Virus Cellular Receptor 2', 'Humans', 'Inflammation Mediators', 'Killer Cells, Natural', 'Lysosomal-Associated Membrane Protein 1', 'Membrane Proteins', 'Middle Aged',... | 24,651,720 | [['M01.060.116'], ['D12.776.395.550.200.250.520.156', 'D12.776.543.550.200.250.520.156', 'D23.050.301.264.894.156', 'D23.050.301.350.250.520.156', 'D23.101.100.894.156'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.37... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
NRAS rs2273267 A>T polymorphism reduces neuroblastoma risk in Chinese children. | Neuroblastoma is an extracranial solid tumor that mainly occurs in childhood. Mutations of NRAS gene have been described in several cancers. However, whether NRAS gene polymorphisms can predict the risk of neuroblastoma have not been investigated. We hypothesized that variations of NRAS gene contribute to neuroblastoma... | ['Alleles', 'Asian Continental Ancestry Group', 'Case-Control Studies', 'Child', 'Child, Preschool', 'China', 'Female', 'GTP Phosphohydrolases', 'Gene Frequency', 'Genes, ras', 'Genetic Predisposition to Disease', 'Genotype', 'Humans', 'Infant', 'Male', 'Membrane Proteins', 'Neuroblastoma', 'Odds Ratio', 'Polymorphism,... | 31,759,987 | [['G05.360.340.024.340.030'], ['M01.686.508.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.252.474.164'], ['D08.811.277.040.330'], ['G05.330'], ['G05.360.340.024.340.375.500.791.550'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'],... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Imaging of naive myopic choroidal neovascularization by spectral-domain optical coherence tomography. | PURPOSE: To assess the tomographic features of myopic choroidal neovascularization by spectral-domain optical coherence tomography.METHODS: We consecutively reviewed the charts of patients with pathologic myopia, recent visual acuity deterioration and active macular neovascularization. Specific tomographic changes were... | ['Adult', 'Aged', 'Aged, 80 and over', 'Choroidal Neovascularization', 'Female', 'Fluorescein Angiography', 'Humans', 'Male', 'Middle Aged', 'Multimodal Imaging', 'Myopia, Degenerative', 'Ophthalmoscopy', 'Retina', 'Retrospective Studies', 'Tomography, Optical Coherence', 'Young Adult'] | 24,751,654 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C11.941.160.244', 'C23.550.589.500.145'], ['E01.370.370.050.350', 'E01.370.380.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.567'], ['C11.744.636.500'], ['E01.370.380.560'], ['A09.371.729'], ['E05.318.372.500.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of Two High-intensity Interval Training Concepts in Recreational Runners. | This study investigated the effects induced by 8 weeks of two high-intensity interval training (HIIT) protocols, 10-20-30 and 30-30 concepts, characterized by significantly different training volume and intensity, on physiological parameters, running performance, body composition and psychophysiological stress of recre... | ['Adult', 'Athletic Performance', 'Body Composition', 'High-Intensity Interval Training', 'Humans', 'Male', 'Oxygen Consumption', 'Running', 'Workload'] | 31,378,863 | [['M01.060.116'], ['I03.450.642.845.054'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['G11.427.410.698.277.311.250', 'I03.350.311.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.680'], ['G11.427.410.568.610', 'G11.427.410.698.277.750', 'I03.350.750', 'I03.450.642.845.610'], ['I03.946.225.500', 'N04.452.6... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
ASSESSMENT OF MECHANICAL AND MANUAL SUTURE IN THE SURGICAL TREATMENT OF THE PHARYNGOESOPHAGEAL DIVERTICULUM. | BACKGROUND: The occurrence of the pharyngoesophageal, or Zenker diverticulum is not frequent in the national scenario, and the technique of the diverticulectomy with cricomyotomy in medium and great dimension diverticula is still the most indicated. Because the resection of the diverticulum requires the suture of the p... | ['Aged', 'Aged, 80 and over', 'Digestive System Surgical Procedures', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pharyngeal Muscles', 'Suture Techniques', 'Zenker Diverticulum'] | 26,734,791 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.567.800', 'A04.623.617', 'A14.724.617'], ['E04.987.775'], ['C06.405.205.282.750.625.900', 'C23.300.415.625.900']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Absorption and secretion of potassium by rabbit descending colon. | Measurements of K fluxes under a variety of conditions have provided an internally consistent set of data that demonstrate active absorption and active secretion of K by rabbit descending colon in vitro. The properties of K diffusion across the paracellular pathway are those of a free solution shunt. With Na and Cl pre... | ['Absorption', 'Animals', 'Biological Transport', 'Colon', 'Electrochemistry', 'Osmolar Concentration', 'Potassium', 'Rabbits', 'Sodium'] | 3,714,449 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['B01.050'], ['G03.143'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['H01.181.529.307'], ['G02.640'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['B01.050.150.900.649.313.968.700'], ['D01.268.549.750', 'D01.26... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
RNA polymerase III initiation on coligo DNA templates containing loops of variable sequence, size and nucleotide chemistry. | Circularized oligonucleotides, or coligos, were previously found to serve as RNA polymerase III (Pol III) templates in vitro and in human tissue culture cells. Here we randomized the 12-nucleotide larger loop (L-loop) of a well characterized coligo and found unexpectedly that in vitro transcription by FLAG-Pol III was ... | ['DNA', 'HEK293 Cells', 'Humans', 'Protein Structure, Secondary', 'RNA Polymerase III'] | 27,593,562 | [['D13.444.308'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.820.709.600'], ['D08.811.913.696.445.735.270.775']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Contractile and biochemical responses of cardiac and skeletal muscle to isoproterenol covalently linked to glass beads. | The effects of (-)-isoproterenol covalently linked to glass beads on inotropic state, cyclic AMP concentration, and phosphorylase b to a conversion was studied in cat and guinea pig papillary muscles. Biochemical responses also were measured in mouse diaphragm sections. In cat papillary muscles under normal conditions ... | ['Animals', 'Cats', 'Chemical Phenomena', 'Chemistry', 'Cyclic AMP', 'Glass', 'Guinea Pigs', 'Isoproterenol', 'Male', 'Mice', 'Muscle Contraction', 'Myocardial Contraction', 'Myocardium', 'Papillary Muscles', 'Phosphorylases', 'Potassium', 'Solubility'] | 192,486 | [['B01.050'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['G02'], ['H01.181'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['J01.637.437'], ['B01.050.150.900.649.313.992.550'], ['D02.033.100.291.439', 'D02.092.063.291.439', 'D02.092.311.649', 'D02.455.426.559.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Necrotizing fasciitis in narcotic addicts. | In its early stages necrotizing fasciitis may mimic an uncomplicated cellulitis, with erythema and only mild swelling and minimal pain. The combination of physical findings in a patient with a current history of drug addiction should arouse suspicion of an underlying fasciitis. An aggressive diagnostic approach includi... | ['Anti-Bacterial Agents', 'Arm', 'Debridement', 'Drainage', 'Fascia', 'Fasciotomy', 'Heroin Dependence', 'Humans', 'Inflammation', 'Male', 'Middle Aged', 'Necrosis', 'Skin Diseases, Vesiculobullous'] | 773,230 | [['D27.505.954.122.085'], ['A01.378.800.075'], ['E04.176'], ['E02.309', 'E04.237'], ['A02.340', 'A10.165.425'], ['E04.321'], ['C25.775.643.500.400', 'F03.900.647.500.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['M01.060.116.630'], ['C23.550.717'], ['C17.800.865']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cell Adhesion Molecule CD166 Drives Malignant Progression and Osteolytic Disease in Multiple Myeloma. | Multiple myeloma is incurable once osteolytic lesions have seeded at skeletal sites, but factors mediating this deadly pathogenic advance remain poorly understood. Here, we report evidence of a major role for the cell adhesion molecule CD166, which we discovered to be highly expressed in multiple myeloma cell lines and... | ['Animals', 'Antigens, CD', 'Cell Adhesion Molecules', 'Cell Adhesion Molecules, Neuronal', 'Cell Differentiation', 'Disease Progression', 'Fetal Proteins', 'Humans', 'Mice', 'Mice, Inbred C57BL', 'Multiple Myeloma', 'Osteolysis', 'Transfection', 'Xenograft Model Antitumor Assays'] | 27,634,757 | [['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['D12.776.395.550.200.250', 'D12.776.543.550.200.250', 'D23.050.301.350.250'], ['G04.152'], ['C23.550.291.656'], ['D12.776.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.90... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of chlorine treatment on properties of wheat flour and its components in the presence of sucrose. | Chlorine treatment increases the surface hydrophobicity of starch granules of soft wheat flour and reduces its gluten network forming capacity and apparent content of the flour lipids, the latter presumably by forming chlorinated derivatives. It also increases its solvent holding capacity as shown by proton nuclear mag... | ['Amylose', 'Chlorine', 'Flour', 'Sucrose', 'Triticum', 'Viscosity'] | 30,372,962 | [['D09.301.915.361', 'D09.698.365.855.361'], ['D01.268.380.150', 'D01.362.225'], ['G07.203.300.484', 'J02.500.484'], ['D09.698.629.305.770', 'D09.947.750.770'], ['B01.650.940.800.575.912.250.822.918'], ['G02.930']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Expression of collagen XVII and ubiquitin-binding protein p62 in motor neuron disease. | Collagen involvement in motor neuron disease has been suggested by several earlier studies. Recently, we found collagen XVII to be expressed in locations in the human brain that include those damaged in motor neuron disease. In this study, we examined the extent of motor neuron disease-related changes in the brain of 9... | ['Adaptor Proteins, Signal Transducing', 'Adult', 'Aged', 'Aged, 80 and over', 'Amyotrophic Lateral Sclerosis', 'Autoantigens', 'Biomarkers', 'Brain', 'Cerebellum', 'Comorbidity', 'Cytoskeleton', 'Female', 'Frontal Lobe', 'Hippocampus', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Motor Neuron Disease', 'N... | 18,992,722 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['D23.050.422'], ['D23.101'], ['A08.186.211'], ['A08.186.211.132.810.428.200'], ['N05.715.350.22... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Deletion of the first cysteine-rich region of the varicella-zoster virus glycoprotein E ectodomain abolishes the gE and gI interaction and differentially affects cell-cell spread and viral entry. | Varicella-zoster virus (VZV) glycoprotein E (gE) is the most abundant glycoprotein in infected cells and, in contrast to those of other alphaherpesviruses, is essential for viral replication. The gE ectodomain contains a unique N-terminal region required for viral replication, cell-cell spread, and secondary envelopmen... | ['Animals', 'Cell Line', 'Herpes Zoster', 'Herpesvirus 3, Human', 'Humans', 'Mice', 'Mice, SCID', 'Protein Binding', 'Sequence Deletion', 'Transplantation, Heterologous', 'Viral Envelope Proteins', 'Virulence', 'Virus Assembly', 'Virus Internalization'] | 18,945,783 | [['B01.050'], ['A11.251.210'], ['C01.925.256.466.930.750'], ['B04.280.382.100.900.460'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.780'], ['G02.111.679', 'G03.808'], ['G05.365.590.762', 'G05.558.800'], ['E04.936.764'], ['D... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of age on contractility of guinea pig ureter. | Longitudinal force-length relationships of guinea pig ureter were studied in vitro in animals 3 weeks, 3 months, and 3 years of age. Distal segments of 3-week-olds underwent a greater per cent increase in length in response to an applied resting force than those from older age groups. Resting force-length relations of ... | ['Aging', 'Animals', 'Elasticity', 'Guinea Pigs', 'Stress, Mechanical', 'Ureter'] | 7,372,433 | [['G07.345.124'], ['B01.050'], ['G01.374.590'], ['B01.050.150.900.649.313.992.550'], ['G01.374.835'], ['A05.810.776']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preliminary experience with the Berger neurobiopsy device for ultrasound guided aspiration and biopsy of intracranial lesions. | Our preliminary experience is presented in the use of the Berger neurobiopsy device for ultrasound localization and biopsy of intracranial lesions through a burr hole. The apparatus and technique are described, along with the results of its use in the first 49 patients. In these patients 43 tumours were biopsied, all e... | ['Adolescent', 'Adult', 'Aged', 'Biopsy, Needle', 'Brain', 'Brain Abscess', 'Brain Diseases', 'Brain Neoplasms', 'Child, Preschool', 'Echoencephalography', 'Female', 'Humans', 'Male', 'Middle Aged'] | 1,884,595 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['A08.186.211'], ['C01.207.090', 'C01.830.025.160', 'C10.228.140.116', 'C10.22... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[The correlation between DNA content and Fas antigen in non-small cell lung cancer]. | OBJECTIVE: To study the relationship between Fas protein expression and DNA content in non-small cell lung cancer (NSCLC).METHODS: Fas protein expression and DNA content in resected samples from 33 NSCLC patients and 17 normal controls were detected by flow cytometry. Fas expression and DNA content were compared with c... | ['Aneuploidy', 'Carcinoma, Non-Small-Cell Lung', 'Cell Division', 'DNA, Neoplasm', 'Female', 'Flow Cytometry', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'fas Receptor'] | 12,133,327 | [['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D13.444.308.425'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.24... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Diaspirin crosslinked hemoglobin (DCLHb): absence of increased free radical generation following administration in a rabbit model of renal ischemia and reperfusion. | In control rabbits, a renal ischemia of 60 min followed by 10 min of reperfusion resulted in an enhanced free radical production in cortical tissue, as assessed by a significant decrease of free glutathione (42%), protein-bound GSH (17%), and vitamin E (49%). In contrast, catalase or glutathione peroxidase activities w... | ['Animals', 'Aspirin', 'Cyclic N-Oxides', 'Disease Models, Animal', 'Electron Spin Resonance Spectroscopy', 'Free Radicals', 'Glutathione', 'Hemoglobins', 'Ischemia', 'Kidney', 'Kidney Cortex', 'Nitrogen Oxides', 'Rabbits', 'Reperfusion', 'Spin Labels', 'Vitamin E'] | 7,635,350 | [['B01.050'], ['D02.455.426.559.389.657.410.595.176'], ['D03.661.243'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E05.196.867.519.274'], ['D01.339', 'D02.389'], ['D12.644.456.448'], ['D12.776.124.400', 'D12.776.422.316.762'], ['C23.550.513'], ['A05.810.453'], ['A05.810.453.324'], ['D01.362.635', 'D01.625.550', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glial cell proliferation in the spinal cord after dorsal rhizotomy or sciatic nerve transection in the adult rat. | Proliferation of glial cells is one of the hallmarks of CNS responses to neural injury. These responses are likely to play important roles in neuronal survival and functional recovery after central or peripheral injury. The boundary between the peripheral nervous system (PNS) and CNS in the dorsal roots, the dorsal roo... | ['Age Factors', 'Animals', 'Antibodies, Monoclonal', 'Astrocytes', 'Bromodeoxyuridine', 'Cell Division', 'Cell Survival', 'Denervation', 'Female', 'Ganglia, Spinal', 'Glial Fibrillary Acidic Protein', 'Microglia', 'Nerve Degeneration', 'Nerve Regeneration', 'Rats', 'Rats, Sprague-Dawley', 'Rhizotomy', 'Sciatic Nerve', ... | 10,759,172 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A08.637.200', 'A11.650.200'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.2... | ['Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Transitional vacuole formation following a bolus infusion of PEG-hemoglobin in the rat. | This study was designed to assess the morphological effects of a bolus infusion of PEG-hemoglobin on the heart, lung, liver, spleen and kidney of laboratory rats. Of particular interest was the determination of PEG-hemoglobin's potential to form vacuoles in the tissues and whether these were transitory and article spec... | ['Animals', 'Female', 'Heart', 'Hemoglobins', 'Infusions, Intravenous', 'Kidney', 'Liver', 'Lung', 'Myocardium', 'Polyethylene Glycols', 'Rats', 'Rats, Sprague-Dawley', 'Spleen', 'Vacuoles'] | 8,922,229 | [['B01.050'], ['A07.541'], ['D12.776.124.400', 'D12.776.422.316.762'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['A05.810.453'], ['A03.620'], ['A04.411'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D02.033.455.250.700', 'D05.750.741', 'D25.720.741', 'J01.637.051.720.741'], ['B01.050.150.900.649.313.992... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
HIV-risk behaviour and knowledge about HIV/AIDS among patients with schizophrenia. | BACKGROUND: Recent literature has demonstrated that psychiatric patients, particularly those with a diagnosis of schizophrenia, may be at high risk for HIV infection. In fact, HIV-risk behaviour, such as intravenous drug with sharing needles, promiscuity associated with unprotected sex and high-risk sexual activity aft... | ['Acquired Immunodeficiency Syndrome', 'Adolescent', 'Adult', 'Attitude to Health', 'Female', 'HIV Seropositivity', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Risk-Taking', 'Schizophrenia', 'Schizophrenic Psychology', 'Sexual Behavior', 'Surveys and Questionn... | 10,077,305 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.057'], ['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.500', 'C01.925.782... | ['Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Vertebrobasilar artery dissection presenting with simultaneous subarachnoid hemorrhage and brain stem infarction: case report. | BACKGROUND: Intracranial dissecting aneurysms have been associated with subarachnoid hemorrhage (SAH) or cerebral ischemia. We encountered a patient presenting with simultaneous subarachnoid hemorrhage and brainstem infarction caused by a dissecting aneurysm of the vertebrobasilar artery, which was diagnosed by magneti... | ['Aneurysm, Dissecting', 'Basilar Artery', 'Brain Stem Infarctions', 'Cerebral Angiography', 'Humans', 'Intracranial Aneurysm', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Subarachnoid Hemorrhage', 'Tomography, X-Ray Computed', 'Vertebral Artery'] | 12,633,950 | [['C14.907.055.050'], ['A07.015.114.106'], ['C10.228.140.300.150.477.100', 'C10.228.140.300.775.200.100', 'C14.907.253.092.477.100', 'C14.907.253.855.200.100', 'C23.550.513.355.250.100', 'C23.550.717.489.250.100'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', ... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Referral patterns, treatment choices, and outcomes in locoregional esophageal cancer: a population-based analysis of elderly patients. | PURPOSE To determine the impact of demographics and comorbidity on access to specialists' services, treatment, and outcome for patients with locoregional esophageal cancer. PATIENTS AND METHODS We performed a retrospective cohort study of 3,538 patients older than age 65 years who were diagnosed with locoregional esoph... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Comorbidity', 'Esophageal Neoplasms', 'Female', 'Humans', 'Male', 'Referral and Consultation', 'Sex Factors', 'Survival Analysis', 'Treatment Outcome'] | 17,557,952 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N05.715.350.225', 'N06.850.490.687'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.758.849'], ['N05.715.350.675', 'N... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Medicare depreciation; useful life guidelines--HCFA. Proposed rule. | We are proposing to amend Medicare regulations to clarify which useful life guidelines providers of health care services may use to determine the useful life of a depreciable asset for Medicare reimbursement purposes. Current regulations state that providers must utilize HHS useful life guidelines or, if none have been... | ['Accounting', 'Centers for Medicare and Medicaid Services, U.S.', 'Depreciation', 'Medicare', 'United States'] | 10,299,181 | [['N03.219.463.030'], ['I01.409.418.750.600.310', 'N03.540.348.500.500.600.550'], ['N03.219.463.030.120'], ['N03.219.521.346.506.564.663', 'N03.219.521.576.343.840', 'N03.706.615.696'], ['Z01.107.567.875']] | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Carcinoma of the pyriform sinus: a retrospective analysis of treatment results over a 20-year period. | One hundred and one patients with pyriform sinus carcinoma treated at the Netherlands Cancer Institute were studied retrospectively. The patients were staged according to the UICC criteria of 1987: there were no stage I, 23 stage II, 30 stage III, and 48 stage IV patients. The treatment consisted of radiotherapy (n = 4... | ['Adult', 'Aged', 'Carcinoma, Squamous Cell', 'Combined Modality Therapy', 'Female', 'Humans', 'Hypopharyngeal Neoplasms', 'Hypopharynx', 'Laryngeal Neoplasms', 'Larynx', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Staging', 'Prognosis', 'Retrospective Studies', 'Survival Rate', 'Treatment Outcome'] | 7,554,339 | [['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.710.485', 'C07.550.745.436', 'C09.647.710.485', 'C09.775.549.485'], ['A04.623.490', 'A14.724.490'], ['C04.588.443.665.481', 'C08.360.369', 'C08.785.481',... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transcriptional activation of the human villin gene during enterocyte differentiation. | Enterocyte differentiation occurs along the crypt-villus axis and is generally thought to involve the transcriptional activation of cell-specific genes, among which is the brush-border structural protein villin. We have examined the molecular mechanisms of villin induction using both in vivo and in vitro systems. Total... | ['Animals', 'Cell Differentiation', 'Cells, Cultured', 'Enterocytes', 'Humans', 'Microfilament Proteins', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Transcription, Genetic'] | 9,834,375 | [['B01.050'], ['G04.152'], ['A11.251'], ['A03.556.124.369.290', 'A10.615.550.444.290', 'A11.436.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.730', 'D12.776.220.525'], ['D13.444.735.544'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['G02.111.873... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nutrient intake and biochemical markers of nutritional status during long-term follow-up after total and partial gastrectomy. | Dietary intake and biochemical nutritional status was studied in patients who had undergone total gastrectomy (TG, n = 10) or partial gastrectomy (PG, n = 10) several years ago. The dietary intake of energy, macronutrients and micronutrients was very similar in the two groups and was also similar to the intake reported... | ['Biomarkers', 'Female', 'Follow-Up Studies', 'Gastrectomy', 'Humans', 'Malabsorption Syndromes', 'Male', 'Nutrition Assessment', 'Nutrition Surveys', 'Nutritional Status', 'Sweden'] | 1,600,923 | [['D23.101'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.210.419'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.637', 'C18.452.603'], ['E05.318.308.585', 'N05.715.360.300.560', 'N06.850.505.557', 'N06.850.520.308.585'], ['E05.318.308.980.485', 'N0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Complete embedding and close step-sectioning of radical prostatectomy specimens both increase detection of extra-prostatic extension, and correlate with increased disease-free survival by stage of prostate cancer patients. | The objectives of this work were to evaluate the efficacy of controlled close step-sectioned and whole-mounted radical prostatectomy specimen processing in prediction of clinical outcome as compared to the traditional processing techniques. Two-hundred and forty nine radical prostatectomy (RP) specimens were whole-moun... | ['Adult', 'Aged', 'Aged, 80 and over', 'Disease-Free Survival', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Prostatectomy', 'Prostatic Neoplasms', 'Tissue Embedding'] | 12,496,984 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.625'], ['E04.950.774... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Endoscopic lateralization of the vocal cord in abductor paralysis of the larynx. | Endoscopic surgical operations of the larynx have many desirable features, including the conservative nature of these procedures, plus the ability to produce surgical changes predictable from the onset. For several years the direct lateralization of the vocal ligament after the removal of a preassessed amount of thyroa... | ['Cautery', 'Humans', 'Laryngoscopy', 'Larynx', 'Tissue Adhesions', 'Vocal Cord Paralysis', 'Vocal Cords'] | 502,699 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mental health affects future employment as job loss affects mental health: findings from a longitudinal population study. | BACKGROUND: Workforce participation is a key feature of public mental health and social inclusion policies across the globe, and often a therapeutic goal in treatment settings. Understanding the reciprocal relationship between participation and mental health has been limited by inadequate research methods. This is the ... | ['Adult', 'Employment', 'Female', 'Humans', 'Male', 'Mental Disorders', 'Mental Health', 'Middle Aged', 'Risk Factors', 'Unemployment', 'Workplace'] | 23,705,753 | [['M01.060.116'], ['N01.824.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['F02.418', 'N01.400.500'], ['M01.060.116.630'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'], ['N01.824.245.850'], ['N01.824.245.925', ... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Thyroid hormone receptor beta2 is strongly up-regulated at all levels of the hypothalamo-pituitary-thyroidal axis during late embryogenesis in chicken. | In this study, we tried to elucidate the changes in thyroid hormone (TH) receptor beta2 (TRbeta2) expression at the different levels of the hypothalamo-pituitary-thyroidal (HPT) axis during the last week of chicken embryonic development and hatching, a period characterized by an augmented activity of the HPT axis. We q... | ['Animals', 'Chick Embryo', 'Chickens', 'Diencephalon', 'Embryo, Nonmammalian', 'Gene Expression Regulation, Developmental', 'Hypothalamo-Hypophyseal System', 'Pituitary Gland', 'RNA, Messenger', 'Retina', 'Thyroid Gland', 'Thyroid Hormone Receptors beta', 'Up-Regulation'] | 18,310,447 | [['B01.050'], ['A13.350.150', 'A16.331.200'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A08.186.211.200.317'], ['A13.350', 'A16.331'], ['G05.308.310'], ['A06.688.357', 'A08.186.211.180.497.352.435', 'A08.186.211.200.317.357.352.435', 'A08.713.357'], ['A06.300.747', 'A06.688.357.750', 'A08.186.21... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of NAP-22 and GAP-43 (neuromodulin) as major protein components in a Triton insoluble low density fraction of rat brain. | NAP-22 is a membrane-localized brain enriched acidic protein having a Ca(2+)-dependent calmodulin binding activity. Further fractionation of the NAP-22 containing membrane showed the localization of NAP-22 in a Triton insoluble fraction of low density. Besides NAP-22, this fraction was found to contain GAP-43 (neuromod... | ['Amino Acid Sequence', 'Animals', 'Brain Chemistry', 'Calmodulin-Binding Proteins', 'Centrifugation, Density Gradient', 'Chromatography, High Pressure Liquid', 'Cytoskeletal Proteins', 'Electrophoresis, Gel, Two-Dimensional', 'GAP-43 Protein', 'GTP-Binding Proteins', 'Membrane Glycoproteins', 'Molecular Sequence Data'... | 9,030,206 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.150', 'G03.185'], ['D12.776.157.142'], ['E05.181.724.336', 'E05.196.941.336'], ['E05.196.181.400.300'], ['D12.776.220'], ['E05.196.401.250', 'E05.301.300.230'], ['D12.776.395.550.400', 'D12.776.543.550.400', 'D12.776.631.400'], ['D08.811.277.040.330.30... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Dlx5 drives Runx2 expression and osteogenic differentiation in developing cranial suture mesenchyme. | Craniofacial bones derive from cephalic neural crest, by endochondral or intramembranous ossification. Here, we address the role of the homeobox transcription factor Dlx5 during the initial steps of calvaria membranous differentiation and we show that Dlx5 elicits Runx2 induction and full osteoblast differentiation in ... | ['Alkaline Phosphatase', 'Animals', 'Antigens, Differentiation', 'Cell Differentiation', 'Cells, Cultured', 'Chick Embryo', 'Core Binding Factor Alpha 1 Subunit', 'Cranial Sutures', 'Homeodomain Proteins', 'Mesoderm', 'Osteogenesis', 'Osteopontin', 'Transcription Factors'] | 17,335,796 | [['D08.811.277.352.650.035'], ['B01.050'], ['D23.050.301.264', 'D23.101.100'], ['G04.152'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['D12.776.930.155.200.100'], ['A02.835.232.781.200'], ['D12.776.260.400'], ['A16.504.660'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.500.729'], ['D12.644.276.374.625',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Diffuse lung involvement in primary amyloidosis as an infrequent cause of interstitial lung disease. Clinical case]. | We report a 50 years old female, admitted to the hospital due to malaise lasting 7 months, with diffuse bilateral lung infiltrates and a progressive respiratory insufficiency, dying one month after admission. A transbronchial biopsy disclosed an extensive amyloid infiltration. The necropsy confirmed this finding and sh... | ['Amyloidosis', 'Fatal Outcome', 'Humans', 'Lung Diseases, Interstitial', 'Male', 'Middle Aged', 'Multiple Myeloma'] | 9,609,038 | [['C18.452.845.500'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.483'], ['M01.060.116.630'], ['C04.557.595.500', 'C14.907.454.460', 'C15.378.147.780.650', 'C15.378.463.515.460', 'C20.683.515... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A subset of the histone H3 lysine 9 methyltransferases Suv39h1, G9a, GLP, and SETDB1 participate in a multimeric complex. | Lysine 9 of histone 3 (H3K9) can be mono-, di-, or trimethylated, inducing distinct effects on gene expression and chromatin compaction. H3K9 methylation can be mediated by several histone methyltransferases (HKMTs) that possess mono-, di-, or trimethylation activities. Here we provide evidence that a subset of each of... | ['DNA, Satellite', 'Enzyme Stability', 'Gene Expression Regulation', 'HeLa Cells', 'Histocompatibility Antigens', 'Histone-Lysine N-Methyltransferase', 'Histones', 'Humans', 'Methylation', 'Methyltransferases', 'Protein Methyltransferases', 'Protein Transport', 'Recombinant Fusion Proteins', 'Repressor Proteins'] | 20,129,054 | [['D13.444.308.480', 'G02.111.570.080.708.800.150', 'G05.360.080.708.800.150', 'G05.360.340.024.220.150', 'G05.360.340.024.850.150'], ['E05.916.360', 'G02.111.700.500'], ['G05.308'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['D23.050.301.500', 'D23.050.705.552'], ['D08.811.913.555.500.800.200.500'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Ability to conceive and the course of pregnancy in women after laparoscopic myomectomy]. | The aim of the study was to assess fertility of patients after myomectomy. The study included a group of 32 patients, aged 22-41, who underwent laparoscopic myomectomy. Primary infertility was diagnosed in 23 women (71.8%), whereas secondary infertility in 9 women (28.2%). Indications for surgery were rapid growth of m... | ['Adult', 'Female', 'Fertility', 'Gynecologic Surgical Procedures', 'Humans', 'Infertility', 'Laparoscopy', 'Myoma', 'Pregnancy'] | 15,230,143 | [['M01.060.116'], ['G08.686.210'], ['E04.950.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365', 'C13.351.500.365'], ['E01.370.388.250.520', 'E04.502.250.520'], ['C04.557.450.590.540'], ['G08.686.784.769']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Antitumor trans-N-heterocyclic carbene-amine-Pt(II) complexes: synthesis of dinuclear species and exploratory investigations of DNA binding and cytotoxicity mechanisms. | A series of bimetallic [(NHC)PtX2]2(diamine) complexes have been prepared as a new chemotype for potential anticancer agents. These complexes display an uncommon set of structural features as far as they combine two bifunctional, trans-configured platinum centers. They display cytotoxic activities in the micromolar ran... | ['Antineoplastic Agents', 'Apoptosis', 'Apoptosis Inducing Factor', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Proliferation', 'Cisplatin', 'DNA', 'DNA Fragmentation', 'Diamines', 'Humans', 'Inhibitory Concentration 50', 'Organoplatinum Compounds'] | 23,421,599 | [['D27.505.954.248'], ['G04.146.954.035'], ['D08.811.682.608.047', 'D12.644.360.075.311', 'D12.776.157.687.063', 'D12.776.331.161', 'D12.776.476.075.311', 'D12.776.660.720.063'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Peripheral intrahepatic cholangiocarcinoma occurring in patients without cirrhosis or chronic bile duct diseases: epidemiology and histopathology of distant nontumoral liver in 57 White patients. | BACKGROUND/AIM: Peripheral intrahepatic cholangiocarcinoma (ICC) occurring mainly in the absence of cirrhosis represents an increasing subgroup of primary liver tumors in Western countries. Histopathologic changes in the non-neoplastic liver in this context are not well characterized.PATIENTS AND METHODS: We assessed t... | ['Aged', 'Bile Duct Neoplasms', 'Bile Ducts, Intrahepatic', 'Biopsy', 'Cholangiocarcinoma', 'European Continental Ancestry Group', 'Fatty Liver', 'Fatty Liver, Alcoholic', 'Female', 'France', 'Humans', 'Iron Overload', 'Liver', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Non-alcoholic Fatty Liver Disease', 'Prevalence',... | 23,085,575 | [['M01.060.116.100'], ['C04.588.274.120.250', 'C06.130.120.120', 'C06.130.320.120', 'C06.301.120.250'], ['A03.159.183.158', 'A03.620.150'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C04.557.470.200.025.450'], ['M01.68... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Genetic risk for neuroticism predicts emotional health depending on childhood adversity. | BACKGROUND: Existing evidence for gene ? environment interaction (G ? E) in neuroticism largely relies on candidate gene studies, although neuroticism is highly polygenic. This study aimed to investigate the long-term associations between polygenic risk scores for neuroticism (PRSN), objective childhood adversity and t... | ['Adverse Childhood Experiences', 'Aged', 'Anxiety', 'Cross-Sectional Studies', 'Depression', 'Female', 'Gene-Environment Interaction', 'Genotype', 'Humans', 'Loneliness', 'Male', 'Middle Aged', 'Neuroticism', 'Personal Satisfaction', 'Phenotype', 'Sweden'] | 29,576,022 | [['I01.880.735.035', 'I01.880.853.050'], ['M01.060.116.100'], ['F01.470.132'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.126.350'], ['G05.695.337'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.470.713', 'I01.880.853.748.435'], ['M01.060.116.630'], [... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
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