Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Structure of hypothetical Mo-cofactor biosynthesis protein B (ST2315) from Sulfolobus tokodaii. | The structure of a probable Mo-cofactor biosynthesis protein B from Sulfolobus tokodaii, belonging to space group P6(4)22 with unit-cell parameters a = b = 136.68, c = 210.52 A, was solved by molecular replacement to a resolution of 1.9 A and refined to an R factor and R(free) of 16.8% and 18.5%, respectively. The asym... | ['Archaeal Proteins', 'Cloning, Molecular', 'Coenzymes', 'Crystallography, X-Ray', 'Escherichia coli', 'Escherichia coli Proteins', 'Genes, Archaeal', 'Hydrogen Bonding', 'Metalloproteins', 'Models, Molecular', 'Protein Conformation', 'Protein Structure, Quaternary', 'Protein Subunits', 'Pteridines', 'Recombinant Prote... | 20,054,111 | [['D12.776.090'], ['E05.393.220'], ['D08.211'], ['E05.196.309.742.225'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G05.360.340.024.340.364.124', 'G05.360.340.358.024.124', 'G05.360.340.358.050.500'], ['G02.282'], ['D12.776.556'], ['E05.599.595'], ['G02.111.570.820.709'], ['G02.111.5... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
After a stroke: strategies to restore function and prevent complications. | Mortality and morbidity are high in elderly stroke patients. Early mobilization and prevention of stroke-related complications improve their ability to participate in a more intense and comprehensive rehabilitation program. An interdisciplinary approach to stroke rehabilitation restores functional loss, improves qualit... | ['Aged', 'Automobile Driving', 'Cerebrovascular Disorders', 'Home Care Services', 'Hospitalization', 'Humans', 'Outpatients', 'Patient Care Team', 'Patient Education as Topic', 'Patient Selection', 'Primary Health Care', 'Prognosis', 'Recurrence'] | 9,307,573 | [['M01.060.116.100'], ['I03.125'], ['C10.228.140.300', 'C14.907.253'], ['N02.421.143.524', 'N02.421.539.089'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.630'], ['N04.590.715'], ['I02.233.332.500', 'N02.421.726.407.680'], ['E05.581.500.653', 'N04.590.731'], ['N04.590.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A new in vitro test method for calcification of bioprosthetic heart valves. | To investigate the calcification behavior of different bioprosthetic heart valves and verify possible hypotheses of the etiology of valve calcification, an accelerated pulse tester for bioprostheses was developed, whereby up to ten valves can be tested under identical test conditions. Each valve was mounted in a separa... | ['Animals', 'Bioprosthesis', 'Calcinosis', 'Cattle', 'Heart Valve Prosthesis', 'Humans', 'In Vitro Techniques', 'Materials Testing', 'Microradiography', 'Spectrophotometry, Atomic', 'Staining and Labeling', 'Swine'] | 9,209,927 | [['B01.050'], ['E07.695.100'], ['C18.452.174.130'], ['B01.050.150.900.649.313.500.380.271'], ['E07.695.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['E05.570'], ['E01.370.350.700.510'], ['E05.196.712.726.551', 'E05.196.867.826.551'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.20... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Linear and cyclic LFA-1 and ICAM-1 peptides inhibit T cell adhesion and function. | Short peptides derived from functional proteins have been used in several instances to inhibit activity of the parent proteins. In some cases, stability and efficacy were found to be increased by cyclization of these peptides. Inhibition of interaction of the two cell adhesion counter receptors leukocyte function-assoc... | ['Amino Acid Sequence', 'CD18 Antigens', 'Cell Adhesion', 'Cell Division', 'Cells, Cultured', 'Humans', 'Intercellular Adhesion Molecule-1', 'Leukocytes, Mononuclear', 'Lymphocyte Function-Associated Antigen-1', 'Molecular Sequence Data', 'Palatine Tonsil', 'Peptides', 'Protein Binding', 'T-Lymphocytes'] | 11,035,201 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.395.550.200.275.750', 'D12.776.543.550.200.275.750', 'D12.776.543.750.705.408.200.249', 'D12.776.543.750.705.408.600.100.750', 'D12.776.543.750.705.833.249.750', 'D23.050.301.264.894.118', 'D23.050.301.350.275.750', 'D23.101.100.894.118'], ['G04.022'], ['G04.144.22... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Survey of yeasts for antagonistic activity against Salmonella Poona in cantaloupe juice and wounds in rinds coinfected with phytopathogenic molds. | Application of yeasts as biocontrol agents to prevent mold decay of fruits and vegetables has been described. We examined 10 yeasts for potential antagonistic activity against survival and growth of Salmonella Poona in cantaloupe juice and decay by Cladosporium cladosporioides and Geotrichum candidum in wounds on canta... | ['Colony Count, Microbial', 'Cucumis melo', 'Food Handling', 'Food Microbiology', 'Food Preservation', 'Salmonella', 'Temperature', 'Time Factors', 'Yeasts'] | 15,508,621 | [['E01.370.225.875.220', 'E05.200.875.220'], ['B01.650.940.800.575.912.250.300.188.444'], ['J01.576.423.200'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['J01.576.423.850.700'], ['B03.440.450.425.800', 'B03.660.250.150.710'], ['G... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Readiness of high-risk populations in the HIV Network for Prevention Trials to participate in HIV vaccine efficacy trials in the United States. | OBJECTIVE: To determine the willingness of populations at high risk of HIV-1 infection to participate in HIV vaccine efficacy trials, determine factors influencing decision-making, and evaluate knowledge levels of vaccine trial concepts.DESIGN: Cross-sectional study.METHODS: HIV-1-negative homosexual men, male and fema... | ['AIDS Vaccines', 'Clinical Trials as Topic', 'Cross-Sectional Studies', 'Female', 'HIV Infections', 'Health Education', 'Humans', 'Male', 'Risk Factors', 'United States'] | 9,619,811 | [['D20.215.894.899.050'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['I02.233.33... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
A phase 1 study of prasugrel in patients with sickle cell disease: effects on biomarkers of platelet activation and coagulation. | INTRODUCTION: Prasugrel, a P2Y₁₂ adenosine diphosphate (ADP) receptor antagonist effectively inhibits ADP-mediated platelet activation and aggregation, and may be useful in reducing vaso-occlusive crises in sickle cell disease (SCD). In this study, we assess the effect of prasugrel on biomarkers of platelet activation ... | ['Adenosine Diphosphate', 'Adult', 'Anemia, Sickle Cell', 'Biomarkers', 'Blood Coagulation', 'Blood Platelets', 'Female', 'Humans', 'Male', 'Middle Aged', 'Piperazines', 'Platelet Activation', 'Prasugrel Hydrochloride', 'Purinergic P2Y Receptor Antagonists', 'Thiophenes', 'Young Adult'] | 24,368,019 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['M01.060.116'], ['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['D23.101'], ['G09.188.390.150'], ['A11.118.188', 'A15.145.229.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Affective reactions to employment and unemployment as a function of prior expectations and motivation. | Self-esteem and depressive affect measures were obtained from 809 employed and 137 unemployed young people and compared with at-school measures taken three years earlier. Scores were analysed in relation to at-school expectations of obtaining employment and expressed importance of getting a job. In both employed and un... | ['Adolescent', 'Adult', 'Aspirations, Psychological', 'Depression', 'Employment', 'Female', 'Follow-Up Studies', 'Humans', 'Job Satisfaction', 'Male', 'Motivation', 'Self Concept', 'Set, Psychology', 'Unemployment'] | 7,984,731 | [['M01.060.057'], ['M01.060.116'], ['F01.658.100', 'F02.784.629.155'], ['F01.145.126.350'], ['N01.824.245'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.784.692.425'], ['F01.658', 'F01.752.543.500.750'], ['F01.752.747.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
How Do Actions Influence Attitudes? An Inferential Account of the Impact of Action Performance on Stimulus Evaluation. | Over the past decade, an increasing number of studies have shown that the performance of specific actions (e.g., approach and avoidance) in response to a stimulus can lead to changes in how that stimulus is evaluated. In contrast to the reigning idea that these effects are mediated by the automatic formation and activa... | ['Association', 'Attitude', 'Avoidance Learning', 'Choice Behavior', 'Humans'] | 30,229,697 | [['F02.463.425.069', 'F04.754.720.346'], ['F01.100'], ['F02.463.425.097', 'F02.463.785.373.173'], ['F02.463.785.373.346'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Experimental evidence needed to demonstrate inter- and trans-generational effects of ancestral experiences in mammals. | Environmental factors routinely influence an organism's biology. The inheritance or transmission of such influences to descendant generations would be an efficient mode of information transfer across generations. The developmental stage at which a specific environment is encountered by the ancestral generation, and the... | ['Animals', 'Environment', 'Inheritance Patterns', 'Mammals', 'Mice', 'Models, Genetic', 'Phylogeny'] | 25,154,497 | [['B01.050'], ['G16.500.275', 'N06.230'], ['G05.420'], ['B01.050.150.900.649'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.599.395.397'], ['G05.697', 'G16.075.605', 'L01.100.697']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Unconventional gas development facilitates plant invasions. | Vegetation removal and soil disturbance from natural resource development, combined with invasive plant propagule pressure, can increase vulnerability to plant invasions. Unconventional oil and gas development produces surface disturbance by way of well pad, road, and pipeline construction, and increased traffic. Littl... | ['Ecosystem', 'Introduced Species', 'Natural Gas', 'Pennsylvania', 'Plants', 'Soil'] | 28,735,205 | [['G16.500.275.157', 'N06.230.124'], ['B01.050.050.580', 'G16.500.275.157.049.400', 'N06.230.124.049.400'], ['D20.345.369', 'N06.230.132.258.369'], ['Z01.107.567.875.075.550', 'Z01.107.567.875.350.550', 'Z01.107.567.875.500.550'], ['B01.650'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Ethics constructed through the process of nurse training: conceptions, spaces and strategies. | OBJECTIVE: to discuss the professors' conceptions about the ethical dimension of nurse training based on the relationships which this establishes with the competencies with the professional profile; and to identify the spaces and strategies for the teaching of ethics in this process.METHOD: A qualitative study delineat... | ['Education, Nursing', 'Ethics, Nursing'] | 23,459,898 | [['I02.358.462'], ['K01.752.566.479.171.132.875', 'K01.752.712.416', 'N05.350.340.162.750']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Reactive nitrogen species in acetaminophen-induced mitochondrial damage and toxicity in mouse hepatocytes. | Acetaminophen (APAP) toxicity in primary mouse hepatocytes occurs in two phases. The initial phase (0-2 h) occurs with metabolism to N-acetyl-p-benzoquinoneimine which depletes glutathione, and covalently binds to proteins, but little toxicity is observed. Subsequent washing of hepatocytes to remove APAP and reincubati... | ['Acetaminophen', 'Animals', 'Benzoquinones', 'Glutathione', 'Hepatocytes', 'Imines', 'Indazoles', 'Lysine', 'Mice', 'Mitochondria', 'Oxidative Stress', 'Reactive Nitrogen Species'] | 20,578,685 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['B01.050'], ['D02.806.250'], ['D12.644.456.448'], ['A11.436.348'], ['D02.491'], ['D03.383.129.539.487', 'D03.633.100.449'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.284.430.214.190.875.564', 'A11.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vivo prophylactic effects of oleanolic acid isolated from chloroform extract of Flaveria trinervia against ethanol induced liver toxicity in rats. | The prophylactic effects of oleanolic acid (OA) isolated from chloroform extract (CE) of Flaveria trinervia against ethanol induced liver toxicity was investigated using rats. CE and OA at three different doses were tested by administering orally to the ethanol treated animals during the last week of the 7 weeks study.... | ['Animals', 'Antioxidants', 'Biphenyl Compounds', 'Chloroform', 'Chromatography, Thin Layer', 'Ethanol', 'Female', 'Flaveria', 'Free Radicals', 'Hepatitis, Alcoholic', 'Liver', 'Liver Function Tests', 'Magnetic Resonance Spectroscopy', 'Molecular Structure', 'Oleanolic Acid', 'Picrates', 'Plant Extracts', 'Rats', 'Rats... | 23,139,132 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.455.426.559.389.185'], ['D02.455.526.439.224', 'D02.455.526.913.810'], ['E05.196.181.400.537'], ['D02.033.375'], ['B01.650.940.800.575.912.250.100.349'], ['D01.339', 'D02.389'], ['C06.552.380.290', 'C06.552.645.490', 'C25.775.100.087.645... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular epidemiology of norovirus in asymptomatic food handlers in Busan, Korea, and emergence of genotype GII.17. | The molecular epidemiology of norovirus infections was studied in food handlers without any symptoms from January to December 2015 in Busan city, Korea. A total of 2,174 fecal specimens from asymptomatic food handlers were analyzed, and 2.3% (49/2,174) were norovirus-positive. Fourteen of 335 samples (4.2%) were positi... | ['Asymptomatic Infections', 'Caliciviridae Infections', 'Disease Outbreaks', 'Feces', 'Female', 'Food Handling', 'Gastroenteritis', 'Genotype', 'Humans', 'Male', 'Norovirus', 'Phylogeny', 'RNA, Viral', 'Republic of Korea', 'Sequence Analysis, DNA'] | 27,687,231 | [['C01.125', 'C23.550.291.187.500'], ['C01.925.782.160'], ['N06.850.290'], ['A12.459'], ['J01.576.423.200'], ['C06.405.205'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.578.298.550'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.828'], ['Z01.252.474.557.750'], ['E05.393.760.700'... | ['Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
Nicotinic cholinergic agonists inhibit androgen biosynthesis by cultured rat testicular cells. | The actions of cholinomimetics on androgen biosynthesis were investigated using a primary culture of testicular cells derived from adult hypophysectomized rats. Testicular cells were maintained in serum-free medium and treated with hCG and/or drugs on day 8 of culture. Media were collected 2 days later for measurement ... | ['Androgens', 'Animals', 'Bethanechol', 'Bethanechol Compounds', 'Cells, Cultured', 'Chorionic Gonadotropin', 'Cyclic AMP', 'Dimethylphenylpiperazinium Iodide', 'Leydig Cells', 'Lobeline', 'Male', 'Muscarine', 'Nicotine', 'Parasympathomimetics', 'Rats', 'Receptors, Nicotinic', 'Testis', 'Testosterone'] | 2,864,237 | [['D27.505.696.399.472.161'], ['B01.050'], ['D02.092.877.883.088.100', 'D02.241.081.251.133.100', 'D02.675.276.148.100'], ['D02.092.877.883.088', 'D02.241.081.251.133', 'D02.675.276.148'], ['A11.251'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['D03.633.100.759.646.138.39... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Short- and long-term dopaminergic effects on dysarthria in early Parkinson's disease. | While the beneficial effect of levodopa on motor impairment in Parkinson's disease (PD) has been well documented, its effect on speech has rarely been examined and the respective literature is inconclusive. The aim of our study was to analyze the effect of short-term levodopa admission and long-term dopaminergic treatm... | ['Adult', 'Aged', 'Dopamine Agents', 'Dysarthria', 'Female', 'Follow-Up Studies', 'Humans', 'Language Tests', 'Levodopa', 'Male', 'Middle Aged', 'Parkinson Disease', 'Phonetics', 'Reading', 'Severity of Illness Index', 'Sex Factors', 'Speech', 'Speech Production Measurement', 'Time Factors'] | 20,012,657 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.625.150', 'D27.505.696.577.150'], ['C10.597.606.150.500.800.150.200', 'C23.888.592.604.150.500.800.150.200'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513.240... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Mitral homograft replacement of the tricuspid valve for endocarditis. | An infected tricuspid valve was successfully replaced with a fresh mitral homograft. This operation is preferable to valvectomy alone or the use of a stented prosthesis in terms of hemodynamics and resistance to infection. | ['Endocarditis', 'Female', 'Humans', 'Middle Aged', 'Mitral Valve', 'Transplantation, Homologous', 'Tricuspid Valve', 'Tricuspid Valve Insufficiency'] | 9,146,356 | [['C14.280.282'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07.541.510.507'], ['E04.936.864'], ['A07.541.510.893'], ['C14.280.484.856']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effect of melatonin on sleep disorders in a monkey model of Parkinson's disease. | OBJECTIVES: To evaluate and compare the effects of melatonin and levodopa (L-dopa) on sleep disorders in a monkey model of Parkinson's disease.MATERIALS AND METHODS: The daytime and nighttime sleep patterns of four macaques that were rendered parkinsonian by administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridin... | ['Animals', 'Antiparkinson Agents', 'Central Nervous System Depressants', 'Disease Models, Animal', 'Levodopa', 'Macaca fascicularis', 'Male', 'Melatonin', 'Parkinson Disease', 'Sleep Wake Disorders'] | 26,429,753 | [['B01.050'], ['D27.505.954.427.090.050'], ['D27.505.696.277', 'D27.505.954.427.210'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.092.311.200.480', 'D02.455.426.559.389.657.166.175.200.480', 'D12.125.072.050.685.400.500', 'D12.125.072.050.875.130.500'], ['B01.050.150.900.649.313.988.400.112.199.120.510.520'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Behavioural, emotional and family functioning of hospitalized children in China and Hong Kong. | PURPOSE: This study examined behavioural and emotional problems, social competence and family functioning of hospitalized Chinese children in Hong Kong and the Chinese Mainland.METHOD: A sample of 210 hospitalized children (ages 2-11 years) and their families participated in the study. The families were from a cross-se... | ['Adult', 'Child', 'Child Behavior', 'Child, Hospitalized', 'China', 'Female', 'Health Status', 'Hong Kong', 'Humans', 'Male', 'Parent-Child Relations', 'Psychology, Child', 'Regression Analysis', 'Risk Factors', 'Stress, Psychological', 'Surveys and Questionnaires'] | 14,764,013 | [['M01.060.116'], ['M01.060.406'], ['F01.145.179'], ['M01.643.259'], ['Z01.252.474.164'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['Z01.252.474.164.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.370.290'], ['F04.096.628.193'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Outcomes of surgical repairs for thoracic aortic pseudoaneurysms after cardiovascular surgery. | AIM: A thoracic aortic pseudoaneurysm is a life-threatening complication after cardiovascular surgery. We reviewed the short- and long-term outcomes following the surgical repair of thoracic aortic pseudoaneurysms.METHODS: We reviewed 20 patients (mean age, 63.3 ± 10.8 years) who underwent surgical repair for a thoraci... | ['Adult', 'Aged', 'Aneurysm, False', 'Aortic Aneurysm, Thoracic', 'Blood Vessel Prosthesis', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Time Factors', 'Tomography, X-Ray Computed', 'Treatment Outcome', 'Vascular Surgical Procedures'] | 27,375,154 | [['M01.060.116'], ['M01.060.116.100'], ['C14.907.055.090'], ['C14.907.055.239.125', 'C14.907.109.139.125'], ['E07.695.110'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.3... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Temporal Analysis of Cardiovascular and Respiratory Complexity by Multiscale Entropy Based on Symbolic Dynamics. | The effect of an orthostatic stress on cardiovascular and respiratory complexity was investigated to detect impaired autonomic regulation in patients with vasovagal syncope (VVS). A total of 16 female patients and 12 age-matched healthy female subjects were enrolled in a passive 70° head-up tilt test. Also, 12 age-matc... | ['Adult', 'Algorithms', 'Blood Pressure', 'Entropy', 'Female', 'Heart Function Tests', 'Humans', 'Male', 'Signal Processing, Computer-Assisted', 'Syncope, Vasovagal', 'Tilt-Table Test', 'Young Adult'] | 28,991,754 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G01.906.345'], ['E01.370.370.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.800'], ['C10.177.575.600.800', 'C10.597.606.358.800.600.500', 'C23.888.592.604.359.800.600.500'], ['E01.370.370.750'], ['M01.060.116.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Identification and validation of metastasis-associated proteins in head and neck cancer cell lines by two-dimensional electrophoresis and mass spectrometry. | Despite improvements in treatment of patients with head and neck squamous cell carcinoma (HNSCC) over the last two decades, the survival rate of these patients has not increased significantly. One of the major factors in the poor outcome of the disease is regional metastasis. To better understand the mechanisms of this... | ['Amino Acid Sequence', 'Annexin A1', 'Annexin A2', 'Calcium-Binding Proteins', 'Carcinoma, Squamous Cell', 'Electrophoresis, Gel, Two-Dimensional', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Head and Neck Neoplasms', 'Humans', 'Lymphatic Metastasis', 'Mass Spectrometry', 'Molecular Sequenc... | 12,090,472 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.157.125.050.050'], ['D12.776.157.125.050.060'], ['D12.776.157.125'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.196.401.250', 'E05.301.300.230'], ['E05.393.332'], ['G05.308.370'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.69... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Weight loss, renal insufficiency, aortal stenosis and arthralgias]. | The 68-year-old male patient complained of weight loss and -- since 15 years -- of arthralgias and had renal insufficiency and an aortic stenosis. Despite the lack of intestinal symptoms, M. Whipple could be diagnosed, being responsible for his symptoms and clinical signs. Under antibiotic and supportive treatment the ... | ['Aged', 'Anti-Bacterial Agents', 'Aortic Valve Stenosis', 'Arthralgia', 'Humans', 'Male', 'Renal Insufficiency', 'Treatment Outcome', 'Weight Loss', 'Whipple Disease'] | 15,772,857 | [['M01.060.116.100'], ['D27.505.954.122.085'], ['C14.280.484.048.750', 'C14.280.955.249'], ['C05.550.091', 'C23.888.592.612.094', 'F02.830.816.444.350', 'G11.561.790.444.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780', 'C13.351.968.419.780'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.36... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Effect of fertilizers on the number of bacteria involved in the turnover of nitrogen in pond water of the Astrakhan Region]. | The type of intensification affects the distribution of bacteria involved in turnover of nitrogen in pond water. Green fertilizers (reed) stimulate the number of nitrogen-fixing bacteria, and the number and activity of nitrifying bacteria, to a higher degree than nitrogen and phosphorus fertilizers. Reed is recommended... | ['Azotobacter', 'Bacillus', 'Bacteria', 'Fertilizers', 'Fresh Water', 'Nitrobacter', 'Nitrogen', 'Nitrosomonas', 'Pseudomonas', 'Russia', 'Species Specificity', 'Water Microbiology'] | 137,355 | [['B03.440.400.425.625.050', 'B03.660.250.580.022'], ['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['B03'], ['D27.720.031.400'], ['G16.500.275.280', 'N06.230.232'], ['B03.440.400.425.200.520', 'B03.660.050.035.520'], ['D01.268.604', 'D01... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Complement-induced histamine release from human basophils. II. Mechanism of the histamine release reaction. | The activation of human serum complement by incubation with zymosan generates C5a which releases histamine from autologous basophils. The characteristics of the C5a-induced histamine release were investigated. It is similar to IgE-mediated reactions in requiring Ca++ and in being inhibited by EDTA. However, it has mark... | ['Antigens', 'Basophils', 'Calcium', 'Complement C5', 'Complement System Proteins', 'Edetic Acid', 'Histamine Release', 'Humans', 'Hydrogen-Ion Concentration', 'L-Lactate Dehydrogenase', 'Leukocytes', 'Poaceae', 'Temperature', 'Time Factors'] | 56,398 | [['D23.050'], ['A11.118.637.415.120', 'A11.627.340.120', 'A15.145.229.637.415.120', 'A15.382.490.315.120'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.124.486.274.450'], ['D12.776.124.486.274'], ['D02.092.782.258.368.250', 'D02.241.081.018.253'], ['G12.350'], ['B01.050.150.900.649.313.988.400.112.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Distribution of Toxigenic Halomicronema spp. in Adjacent Environments on the Island of Ischia: Comparison of Strains from Thermal Waters and Free Living in Posidonia Oceanica Meadows. | Organisms adaptable to extreme conditions share the ability to establish protective biofilms or secrete defence toxins. The extracellular substances that are secreted may contain monosaccharides and other toxic compounds, but environmental conditions influence biofilm characteristics. Microorganisms that are present in... | ['Alismatales', 'Animals', 'Cyanobacteria', 'Embryo, Nonmammalian', 'Environmental Monitoring', 'Grassland', 'Hot Springs', 'Islands', 'Italy', 'Phylogeny', 'Plant Leaves', 'RNA, Ribosomal, 16S', 'Sea Urchins', 'Seawater', 'Species Specificity'] | 30,747,108 | [['B01.650.940.800.575.912.250.618.050'], ['B01.050'], ['B03.280', 'B03.440.475.100'], ['A13.350', 'A16.331'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G16.500.275.157.531', 'N06.230.124.390'], ['G01.311.355.750.500', 'G16.500.275.260.500'], ['G16.500.275.505', 'N06.230.295', 'Z01.639'], ['Z01.542.489'], ['G05.697... | ['Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Glutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agents. | We studied the effects of sulfur-containing chemopreventive agents, including allyl sulfides and isothiocyanates, on human redox networks. Isothiocyanates inhibited isolated redox-active enzymes in a time- and dose-dependent manner. As shown for the most active compound, benzyl isothiocyanate (BITC), on thioredoxin red... | ["4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid", 'Allyl Compounds', 'Anticarcinogenic Agents', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Proliferation', 'Disulfides', 'Dose-Response Relationship, Drug', 'Glutathione', 'Glutathione Peroxidase', 'Glutathione Transferase', 'Humans', 'Isothiocyanates', 'Oxidati... | 17,937,621 | [['D02.455.426.559.389.150.700.050', 'D02.500.375.050', 'D02.886.250.050'], ['D02.455.326.271.122'], ['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Peritumoral vascular invasion in women with node-negative breast cancer, receiving no adjuvant therapy. | BACKGROUND: The prognostic value of peritumoral vascular invasion (PVI) in node negative breast cancer (N-) is a controversial issue. Considerable debate has focused on how PVI should be defined, and the techniques used to detect them have differed considerably from one study to another.MATERIAL AND METHODS: In our stu... | ['Adult', 'Aged', 'Aged, 80 and over', 'Breast Neoplasms', 'Breast Neoplasms, Male', 'Chemotherapy, Adjuvant', 'Disease-Free Survival', 'Female', 'Follow-Up Studies', 'Humans', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplastic Cells, Circulating', 'Predictive Value of Tests', 'Prognosi... | 10,216,503 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.180', 'C17.800.090.500'], ['C04.588.180.260', 'C17.800.090.500.260'], ['E02.186.170', 'E02.319.170'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Compartmentalization of catalases in Escherichia coli. | Escherichia coli possess three catalase genes: katG codes for protein HPI and katE codes for HPII; katF is also needed for HPII but may be a positive regulatory gene for katE. We have assayed for HPI and HPII in the outer cell membrane, the periplasmic space, the inner membrane, and in the cytoplasm of E. coli. Followi... | ['Catalase', 'Cell Fractionation', 'Cell Membrane', 'Escherichia coli', 'Genes', 'Genes, Bacterial', 'Spheroplasts'] | 3,293,564 | [['D08.811.682.732.332'], ['E05.242.251'], ['A11.284.149'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['A11.868', 'B03.110.761', 'B05.110.761']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Developmental expression of poly(A) binding protein mRNAs during spermatogenesis in the mouse. | The poly(A) binding protein (PABP), a conserved protein that binds to the 3' poly(A) tail on mRNAs in eukaryotic cells, has been implicated in the regulation of mRNA stability and translation. Two PABP cDNAs with different sequences were isolated from mouse testis cDNA libraries. The predicted amino acid sequence of on... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Blotting, Northern', 'Blotting, Southern', 'Consensus Sequence', 'DNA Primers', 'Gene Expression', 'Gene Library', 'Kidney', 'Male', 'Mice', 'Molecular Sequence Data', 'Organ Specificity', 'Poly(A)-Binding Proteins', 'Polymerase Chain Reaction', 'Protein Biosynthesis... | 7,893,484 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['G02.111.570.580.175'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.29... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Rice endosperm-specific plastidial alpha-glucan phosphorylase is important for synthesis of short-chain malto-oligosaccharides. | Previous genetic studies have indicated that the type L alpha-glucan phosphorylase (Pho1) has an essential role during the initiation process of starch biosynthesis during rice seed development. To gain insight into its role in starch metabolism, we characterized the enzymatic properties of the Pho1 recombinant form. P... | ['Endosperm', 'Gene Expression', 'Oligosaccharides', 'Oryza', 'Phosphorylases', 'Plant Proteins', 'Starch'] | 20,045,390 | [['A18.024.500.750.666'], ['G05.297'], ['D09.698.629'], ['B01.650.940.800.575.912.250.822.616'], ['D08.811.913.400.450.460.400'], ['D12.776.765'], ['D05.750.078.562.855', 'D09.301.915', 'D09.698.365.855']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantitative measurement of evolution of postparetic ocular synkinesis treated with botulinum toxin type A. | BACKGROUND: The Sunnybrook Facial Grading System is considered one of the best scales available to grade facial motility and postparetic synkinesis. To measure facial landmarks and movement excursion, a new software, the Facial Assessment by Computer Evaluation, has been proposed. The aim of this study was to quantify ... | ['Adult', 'Aged', 'Botulinum Toxins, Type A', 'Eye', 'Facial Asymmetry', 'Facial Muscles', 'Facial Nerve Diseases', 'Facial Paralysis', 'Female', 'Humans', 'Injections', 'Male', 'Middle Aged', 'Neuromuscular Agents', 'Synkinesis', 'Young Adult'] | 24,165,606 | [['M01.060.116'], ['M01.060.116.100'], ['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['A01.456.505.420', 'A09.371'], ['C23.300.505'], ['A02.633.567.400', 'A14.363'], ['C07.465.299', 'C10.292.319'], ['C07.465.327', 'C10.597.622.214', 'C23.888.592.63... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Incorporating structural characteristics for identification of protein methylation sites. | Studies over the last few years have identified protein methylation on histones and other proteins that are involved in the regulation of gene transcription. Several works have developed approaches to identify computationally the potential methylation sites on lysine and arginine. Studies of protein tertiary structure ... | ['Arginine', 'Asparagine', 'Binding Sites', 'Computer Simulation', 'Glutamic Acid', 'Lysine', 'Methylation', 'Protein Conformation', 'Proteins', 'Surface Properties'] | 19,263,424 | [['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D12.125.068.060', 'D12.125.095.165', 'D12.125.154.049'], ['G02.111.570.120'], ['L01.224.160'], ['D12.125.067.625.349', 'D12.125.119.409.349', 'D12.125.427.300'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['G02.111.035.538', 'G02.607.094.538'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Incremental value of copeptin for rapid rule out of acute myocardial infarction. | OBJECTIVES: The purpose of this study was to examine the incremental value of copeptin for rapid rule out of acute myocardial infarction (AMI).BACKGROUND: The rapid and reliable exclusion of AMI is a major unmet clinical need. Copeptin, the C-terminal part of the vasopressin prohormone, as a marker of acute endogenous ... | ['Aged', 'Aged, 80 and over', 'Biomarkers', 'Female', 'Glycopeptides', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Prospective Studies', 'Troponin T'] | 19,555,842 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101'], ['D09.400.420', 'D12.644.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The comparison of the behavioral observation system and the brief psychiatric rating scale-expanded. | The construct validity of the Behavioral Observation System (BOS), an observational instrument used by line staff to rate psychopathological behaviors, was studied using comparisons with the Brief Psychiatric Rating Scale-Expanded version (BPRS-E). A sample of 100 inpatient participants was rated using the BPRS-E on th... | ['Adult', 'Brief Psychiatric Rating Scale', 'Female', 'Hospitalization', 'Humans', 'Male', 'Mental Disorders', 'Observation', 'Pilot Projects', 'Reproducibility of Results', 'Severity of Illness Index'] | 12,205,724 | [['M01.060.116'], ['F04.711.513.653.083'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['E05.581.249'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Aquaporin 1 is located on the intestinal basolateral membrane in Toxocara canis and might play a role in drug uptake. | BACKGROUND: Aquaporins (AQPs) are a family of integral membrane channel proteins that facilitate the transport of water and other small solutes across cell membranes. AQPs appear to play crucial roles in parasite survival and represent possible drug targets for novel intervention strategy. In this work, we investigated... | ['Animals', 'Aquaporin 1', 'Biological Transport', 'Cell Membrane', 'Drug Delivery Systems', 'Female', 'Helminth Proteins', 'Intestinal Mucosa', 'Male', 'RNA, Messenger', 'Real-Time Polymerase Chain Reaction', 'Reproduction', 'Tissue Distribution', 'Toxocara canis', 'Toxocariasis'] | 31,101,125 | [['B01.050'], ['D12.776.157.530.400.500.040.374', 'D12.776.543.550.450.730.040.374', 'D12.776.543.585.400.730.040.436'], ['G03.143'], ['A11.284.149'], ['E02.319.300'], ['D12.776.419'], ['A03.556.124.369', 'A10.615.550.444'], ['D13.444.735.544'], ['E05.393.620.500.706'], ['G08.686.784'], ['G03.787.917', 'G07.690.725.949... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ionic liquid-anionic surfactant based aqueous two-phase extraction for determination of antibiotics in honey by high-performance liquid chromatography. | An ionic liquid-anionic surfactant based aqueous two-phase extraction was developed and applied for the extraction of tetracycline, oxytetracycline and chloramphenicol in honey. The honey sample was mixed with Na2EDTA aqueous solution. The sodium dodecyl sulfate, ionic liquid 1-octyl-3-methylimidazolium bromide and sod... | ['Anions', 'Anti-Bacterial Agents', 'Bromides', 'Chloramphenicol', 'Chromatography, High Pressure Liquid', 'Edetic Acid', 'Honey', 'Hydrogen-Ion Concentration', 'Imidazoles', 'Ionic Liquids', 'Liquid Phase Microextraction', 'Molecular Structure', 'Oxytetracycline', 'Reproducibility of Results', 'Sodium Chloride', 'Sodi... | 24,767,438 | [['D01.248.497.158'], ['D27.505.954.122.085'], ['D01.139.300.050', 'D01.248.497.158.125'], ['D02.033.455.706.300', 'D02.455.426.559.389.565.175', 'D02.640.529.175'], ['E05.196.181.400.300'], ['D02.092.782.258.368.250', 'D02.241.081.018.253'], ['G07.203.300.581', 'J02.500.581'], ['G02.300'], ['D03.383.129.308'], ['D27.7... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[An epidemiological survey on echinococcosis in Zhiduo County of Qinghai Province]. | The survey was carried out in July, 2006 in Zhiduo County. The IHA and ELISA positive rate in human population was 4.5% (42/933) and 8.2% (76/931) respectively. Ultrasonography revealed a morbidity of 3.4% (33/979) with 3.2% Echinococcus granulosus and 0.2% of E. multilocularis respectively. Animal dissection showed an... | ['Adult', 'Animals', 'Antibodies, Helminth', 'Child', 'Child, Preschool', 'China', 'Dogs', 'Echinococcosis', 'Echinococcus granulosus', 'Enzyme-Linked Immunosorbent Assay', 'Feces', 'Humans', 'Infant', 'Parasite Egg Count', 'Prevalence', 'Wolves'] | 18,038,785 | [['M01.060.116'], ['B01.050'], ['D12.776.124.486.485.114.185', 'D12.776.124.790.651.114.185', 'D12.776.377.715.548.114.185'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.750.250.216.200'], ['C01.610.335.190.396'], ['B01.050.500.500.736.215.327.400'], ['E05.478.566.350.170', 'E05... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Optimal neuromuscular blocking effects of remifentanil during tracheal intubation under general anesthesia. | Objective This study was performed to determine the effect of the remifentanil dose on the onset time of rocuronium with electromyography. Methods This retrospective comparative study included 75 patients undergoing general anesthesia for elective surgery. Patients received lidocaine (40 mg) and propofol (2 mg/kg) foll... | ['Adolescent', 'Adult', 'Analgesics, Opioid', 'Anesthesia, General', 'Anesthetics, Intravenous', 'Case-Control Studies', 'Dose-Response Relationship, Drug', 'Electromyography', 'Female', 'Humans', 'Intubation, Intratracheal', 'Male', 'Middle Aged', 'Neuromuscular Blockade', 'Neuromuscular Nondepolarizing Agents', 'Pros... | 29,722,285 | [['M01.060.057'], ['M01.060.116'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E03.155.197'], ['D27.505.696.277.100.035.075', 'D27.505.954.427.210.100.035.075'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.50... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prevention of endometrial hyperplasia by progesterone during long-term estradiol replacement: influence of bleeding pattern and secretory changes. | OBJECTIVE: To determine the relative influences of induction of withdrawal bleedings secretory transformation, and reduction of mitosis in glands on prevention of endometrial hyperplasia during long-term hormonal replacement therapy.DESIGN: Observational expanded clinical case report.SETTING: Reproductive Endocrine Dep... | ['Biopsy', 'Endometrium', 'Estradiol', 'Estrogen Replacement Therapy', 'Female', 'Hemorrhage', 'Humans', 'Hyperplasia', 'Menopause', 'Mitotic Index', 'Progesterone', 'Regression Analysis'] | 8,486,201 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A05.360.319.679.490'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['E02.319.452.150'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.55... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Application of enhanced recovery after surgery in the treatment of children with congenital choledochal cyst]. | OBJECTIVE: To explore the feasibility of enhanced recovery after surgery (ERAS) in treatment of children with congenital choledochal cyst.METHODS: One hundred and thirty children with congenital choledochal cysts admitted in the Children's Hospital of Zhejiang University from June 2017 to June 2019 were divided into ER... | ['Case-Control Studies', 'Child', 'Choledochal Cyst', 'Enhanced Recovery After Surgery', 'Humans', 'Length of Stay', 'Postoperative Complications'] | 31,901,019 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['C04.182.198', 'C06.130.120.127', 'C06.198.184', 'C16.131.314.184'], ['E04.604.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['C23.550.767']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inversion region for hypertension and brachydactyly on chromosome 12p features multiple splicing and noncoding RNA. | Autosomal-dominant hypertension and brachydactyly (Online Mendelian Inheritance in Man 112410) is a prototype-translational research project. We used interphase fluorescent in situ hybridization and discovered complex rearrangements on chromosome 12p in 5 families but elucidated a common inverted region in the linkage ... | ['Alternative Splicing', 'Cell Division', 'Chromosome Inversion', 'Chromosome Mapping', 'Chromosome Painting', 'Chromosomes, Human, Pair 12', 'Exons', 'Fibroblasts', 'Gene Expression', 'Genes, Dominant', 'Humans', 'Hypertension', 'Interphase', 'Limb Deformities, Congenital', 'MicroRNAs', 'RNA, Untranslated', 'Reverse T... | 18,086,950 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['C23.550.210.190', 'G05.365.590.175.190', 'G05.365.590.770.500', 'G05.558.805.500'], ['E05.393.183'], ['E01.370.225.500.620.670.325.350.125', 'E01.370.225.750.600.670.325.350.12... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Generation of islet-like cells from mouse gall bladder by direct ex vivo reprogramming. | Cell replacement is an emerging therapy for type 1 diabetes. Pluripotent stem cells have received a lot of attention as a potential source of transplantable â-cells, but their ability to form teratomas poses significant risks. Here, we evaluated the potential of primary mouse gall bladder epithelial cells (GBCs) as tar... | ['Animals', 'Cell Differentiation', 'Cells, Cultured', 'Female', 'Gallbladder', 'Humans', 'Islets of Langerhans', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Pluripotent Stem Cells', 'Rats', 'Signal Transduction'] | 23,562,832 | [['B01.050'], ['G04.152'], ['A11.251'], ['A03.159.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.734.414', 'A06.300.414'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['A11.872.700'], ['B01.050.150.900.649.313.992.635.50... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dental extractions in patients with bleeding disorders. The use of fibrin glue. | Eighty patients with various bleeding disorders underwent 135 extractions without preventive replacement hematologic therapy. The local hemostatic control involved the use of fibrin glue Beriplast. Secondary bleeding occurred in 9 of 12 patients with severe hemophilia when the concentration of the aprotinin in the fibr... | ['Adolescent', 'Adult', 'Aged', 'Blood Coagulation Disorders', 'Blood Loss, Surgical', 'Child', 'Child, Preschool', 'Dental Care for Disabled', 'Fibrin Tissue Adhesive', 'Humans', 'Middle Aged', 'Tooth Extraction'] | 8,469,534 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C15.378.100'], ['C23.550.414.300', 'C23.550.505.300'], ['M01.060.406'], ['M01.060.406.448'], ['E06.170.310', 'N02.421.240.190.230'], ['D12.776.124.270.305'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.545.700', 'E06.645.700']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Immunoprecipitation of in vitro-translated products of Nippostrongylus brasiliensis RNA. | RNA has been isolated from adult Nippostrongylus brasiliensis (NB) homogenized in guanidium isothiocyanate. The mRNA has been translated in vitro utilizing a rabbit reticulocyte system and translated products immunoprecipitated with rabbit anti-adult NB antiserum and rat infection serum. | ['Animals', 'Electrophoresis, Agar Gel', 'Electrophoresis, Polyacrylamide Gel', 'Nippostrongylus', 'Precipitin Tests', 'Protein Biosynthesis', 'RNA', 'RNA, Messenger'] | 1,693,674 | [['B01.050'], ['E05.196.401.153', 'E05.301.300.100'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.500.500.294.400.968.400.575'], ['E01.370.225.812.735.645', 'E05.196.150.639.500', 'E05.200.812.735.645', 'E05.478.594.760.645', 'E05.478.605.492'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['D13.444.735'], ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Experimental study of adenovirus-mediated p53 gene on the reversal of multidrug resistance in breast cancer]. | OBJECTIVE: To explore the effects of adenovirus-mediated wild-type p53 gene (Ad-p53) on the reversal of multidrug resistance (MDR) and multidrug resistance gene-1 (MDR1) in adriamycin (ADM) resistant human breast cancer cell.METHODS: Ad-p53 was transfected into the human breast cancer cells of the line MCF-7/ADM. p53 p... | ['ATP Binding Cassette Transporter, Subfamily B, Member 1', 'Adenoviridae', 'Antineoplastic Agents', 'Breast Neoplasms', 'Cell Line, Tumor', 'Cell Survival', 'Doxorubicin', 'Drug Resistance, Multiple', 'Drug Resistance, Neoplasm', 'Female', 'Gene Expression Regulation, Neoplastic', 'Genes, p53', 'Genetic Vectors', 'Hum... | 18,261,311 | [['D12.776.157.530.100.075.063', 'D12.776.157.530.450.074.500.500.250.125', 'D12.776.395.550.020.400.153', 'D12.776.543.550.192.400.153', 'D12.776.543.585.100.200.125', 'D12.776.543.585.450.074.500.500.250.125'], ['B04.280.030'], ['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['A11.251.210.190', 'A11.251.860.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunohistochemical analysis of beta 1-integrin receptors displayed by murine uterine natural killer cells over the course of successful pregnancy. | Granulated metrial gland (GMG) cells are a natural killer (NK) cell-like population present in large numbers in the pregnant rodent uterus. By day 8 of gestation GMG cells are large and granulated and localized to the mesometrial side of each implantation site. GMG cells appear to be highly migratory both in vivo and i... | ['Animals', 'Antibodies', 'Female', 'Fluorescent Antibody Technique', 'Integrin beta1', 'Integrins', 'Killer Cells, Natural', 'Metrial Gland', 'Mice', 'Pregnancy', 'Pregnancy, Animal', 'Receptors, Very Late Antigen'] | 7,537,824 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['D12.776.543.750.705.408.200.500'], ['D12.776.543.750.705.408'], ['A11.118.637.555.56... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spot-1, a novel NLS-binding protein that interacts with p53 through a domain encoded by p(CA)n repeats. | Nuclear Localization Signals (NLS) have been found to mediate the import of proteins into the nucleus. Proteins interacting directly with NLS control the subcellular localization of nucleophilic proteins. The p53 protein is spatially regulated throughout the cell cycle and this regulation has been shown to be dependent... | ['Amino Acid Sequence', 'Base Sequence', 'Cell Line', 'Humans', 'Molecular Sequence Data', 'Nuclear Proteins', 'Phosphoproteins', 'Recombinant Proteins', 'Repetitive Sequences, Nucleic Acid', 'Tumor Suppressor Protein p53'] | 7,675,445 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['D12.776.660'], ['D12.776.744'], ['D12.776.828'], ['G02.111.570.080.708', 'G05.360.080.708'], ['D12.776.157.687.650', 'D12.776.2... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Inhibition of arachidonic acid cascade attenuates the induction of c-Fos proteins by DOI, 5-HT2A/2C receptor agonist, in the rat cortex. | Previous immunohistochemical studies have shown that c-Fos proteins induced by DOI, a 5-HT2A/2C agonist, are present in the population of cortical neurons, which are devoid of 5-HT2A receptors. A mechanism of the induction of c-Fos proteins expression by DOI is still unclear. However, the involvement of the 5-HT2A and ... | ['Amphetamines', 'Animals', 'Arachidonic Acid', 'Dexamethasone', 'Indomethacin', 'Male', 'Parietal Lobe', 'Phospholipases A', 'Phospholipases A2', 'Proto-Oncogene Proteins c-fos', 'Rats', 'Rats, Wistar', 'Serotonin Receptor Agonists'] | 12,020,047 | [['D02.092.471.683.152'], ['B01.050'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D03.633.100.473.420'], ['A08.186.211.200.885.287.500.670'], ['D08.811.277.352.100.680.750'], ['D08.811.277.352.100.680.750.937'], ['D12.776.260.108.765', 'D12.776.624.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Denosumab: a cost-effective alternative for older men with osteoporosis from a Swedish payer perspective. | OBJECTIVE: To assess the cost-effectiveness of denosumab versus other treatments in men with osteoporosis who are ?75years old from a payer perspective in Sweden.METHODS: A lifetime cohort Markov model was developed with seven health states: well, hip fracture, vertebral fracture, other osteoporotic fracture, post-hip ... | ['Aged', 'Antibodies, Monoclonal, Humanized', 'Bone Density Conservation Agents', 'Cohort Studies', 'Cost-Benefit Analysis', 'Denosumab', 'Diphosphonates', 'Female', 'Humans', 'Ibandronic Acid', 'Imidazoles', 'Incidence', 'Male', 'Markov Chains', 'Osteoporosis', 'Osteoporotic Fractures', 'Risk Factors', 'Sweden', 'Trea... | 24,231,131 | [['M01.060.116.100'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D27.505.696.242'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N03.219.151.125'], ['D12.776.124.486.485.114.224.060.782', 'D12.776.124.790.651.114.224.0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A hospital-based survey on food allergy in the population of Kolkata, India. | BACKGROUND: Food allergy is increasing worldwide, and Asian countries are not the exception. Still, ample data are lacking in India. We conducted a cross-sectional study in a metropolis of Eastern India to record the presence of food allergy among the local population.METHODS: The prevalence of food allergy was investi... | ['Adolescent', 'Adult', 'Allergens', 'Cross-Sectional Studies', 'Female', 'Food Hypersensitivity', 'Hospitals', 'Humans', 'India', 'Male', 'Skin Tests', 'Surveys and Questionnaires', 'Young Adult'] | 25,138,428 | [['M01.060.057'], ['M01.060.116'], ['D23.050.063'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C20.543.480.370'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['E01.370.225.812.871', 'E05.200.812.871', 'E05.478.594.890'], ['E05.318.308.980'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Uptake of L-carnitine by rat jejunal brush border microvillous membrane vesicles. Evidence of passive diffusion. | We have previously described apparent active transport of carnitine into rat intestinal mucosa with intracellular accumulation against a concentration gradient in a process dependent upon the presence of sodium ions, oxygen, and energy. In the work described here, we sought to define the interaction between carnitine a... | ['Animals', 'Biological Transport, Active', 'Carnitine', 'Diffusion', 'Intestinal Mucosa', 'Jejunum', 'Male', 'Microvilli', 'Rats', 'Rats, Inbred Strains'] | 2,307,079 | [['B01.050'], ['G03.143.310'], ['D02.092.877.883.099'], ['G01.202', 'G02.196'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124.684.500', 'A03.556.249.750'], ['A11.284.180.565'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Overlapping motifs (PTAP and PPEY) within the Ebola virus VP40 protein function independently as late budding domains: involvement of host proteins TSG101 and VPS-4. | The VP40 protein of Ebola virus can bud from mammalian cells in the form of lipid-bound, virus-like particles (VLPs), and late budding domains (L-domains) are conserved motifs (PTAP, PPxY, or YxxL; where "x" is any amino acid) that facilitate the budding of VP40-containing VLPs. VP40 is unique in that potential overlap... | ['Adenosine Triphosphatases', 'Amino Acid Motifs', 'Cell Line', 'DNA-Binding Proteins', 'Ebolavirus', 'Endosomal Sorting Complexes Required for Transport', 'Humans', 'Membrane Microdomains', 'Nucleoproteins', 'Transcription Factors', 'Viral Core Proteins', 'Virion'] | 12,525,615 | [['D08.811.277.040.025'], ['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['A11.251.210'], ['D12.776.260'], ['B04.820.480.937.300.200'], ['D05.500.199', 'D12.776.543.990.493'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.149.165.570'], ['D12.776.664'], ['D12.776.930'], ['D12.776.964.970.6... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cloning of the chick hsp 90 cDNA in expression vector. | A cDNA clone for the 90kDa heat-shock protein, which we have recently identified as a component of steroid hormone receptors in their heteromeric 8S form, was isolated by direct immunological screening of a chicken smooth muscle cDNA expression library, prepared in the expression plasmids pUC8 and pUC9. Using polyclona... | ['Amino Acid Sequence', 'Animals', 'Base Composition', 'Base Sequence', 'Chickens', 'Cloning, Molecular', 'DNA', 'Genetic Vectors', 'Heat-Shock Proteins', 'Nucleic Acid Hybridization', 'Protein Biosynthesis', 'RNA, Messenger', 'Rabbits', 'Reticulocytes', 'Saccharomyces cerevisiae', 'Species Specificity'] | 3,900,927 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.080'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.393.220'], ['D13.444.308'], ['G05.360.337'], ['D12.776.580.216'], ['E05.393.661', 'G02.111.611'], ['G02.111.660.871'... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Characterization of a nanoparticle-filled resin for application in scan-LED-technology. | Scan-LED-technology is a new rapid prototyping technique with increasing applications in the production of custom-made medical products. The present work is dealing with the examination of a silica/urethandimethacrylate (UDMA) nanocomposite for application in scan-LED-technology. The use of specific LED in a photo-DSC ... | ['2-Propanol', 'Biocompatible Materials', 'Methacrylates', 'Molecular Structure', 'Nanoparticles', 'Polyurethanes', 'Resins, Synthetic', 'Silanes', 'Silicon Dioxide'] | 21,842,140 | [['D02.033.755.615'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D02.241.081.069.600'], ['G02.111.570', 'G02.466'], ['J01.637.512.600'], ['D02.241.081.251.944.750', 'D05.750.716.650', 'D25.720.327.782', 'D25.720.716.650', 'J01.637.051.720.327.782', 'J01.637.051.720.716.650', 'J01.637.412.700'], ['D05.750.716.... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Arthroscopic autologous chondrocyte implantation in osteochondral lesions of the talus: mid-term T2-mapping MRI evaluation. | PURPOSE: Autologous chondrocyte implantation (ACI) in the ankle has become an established procedure to treat osteochondral lesions. However, a non-invasive method able to provide information on the nature of the repair tissue is needed. Recently, MRI T2 mapping was identified as a method capable of qualitatively charac... | ['Adult', 'Ankle Joint', 'Arthroscopy', 'Case-Control Studies', 'Cell Transplantation', 'Chondrocytes', 'Female', 'Follow-Up Studies', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Osteochondrosis', 'Pain Measurement', 'Reference Values', 'Statistics, Nonparametric', 'Talus', 'Transplantation, Autologous', 'Treatmen... | 21,503,808 | [['M01.060.116'], ['A02.835.583.378.062'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E02.095.147.500', 'E04.936.225'], ['A11.329.171'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.35... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A new species of Pythium isolated from the Burgundy region in France. | Pythium nodosum sp. nov. has been isolated from a soil sample taken in the Burgundy region in France. The fungus has spherical to variously shaped proliferating sporangia, smooth-walled oogonia which are crowded with different antheridial branches making a complicated knot around the former, and aplerotic oospores. Mor... | ['Base Sequence', 'Cell Nucleus', 'DNA, Fungal', 'DNA, Ribosomal', 'France', 'Molecular Sequence Data', 'Polymorphism, Restriction Fragment Length', 'Pythium', 'Soil Microbiology'] | 9,465,393 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D13.444.308.300'], ['D13.444.308.475'], ['Z01.542.286'], ['L01.453.245.667'], ['G05.365.795.595'], ['B01.750.580.750'], ['H01.158.273.540.274.555', 'N06.850.425.300']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Healthy Promotion for Fighting Metabolic Syndrome: Insights from Multi-Center HeRO-FiT Cohort. | We know that metabolic syndrome (MS) is a modern cardiovascular (CV) "epidemic", especially in western populations. MS is indeed strictly related to the risk of developing CV diseases (CVD) and/or diabetes. Therefore, the aim of our multi-center study was to promote a "healthy style" for fighting MS. Each participating... | ['Adult', 'Blood Glucose', 'Body Mass Index', 'Health Promotion', 'Humans', 'Metabolic Syndrome', 'Risk Factors', 'Waist Circumference', 'Waist-Hip Ratio'] | 32,731,424 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968.500.570', 'C18.452.625'], ['E05.318.740.600.800.725', 'N05.715.350.2... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A multidimensional perspective on microbial interactions. | Beyond being simply positive or negative, beneficial or inhibitory, microbial interactions can involve a diverse set of mechanisms, dependencies and dynamical properties. These more nuanced features have been described in great detail for some specific types of interactions, (e.g. pairwise metabolic cross-feeding, quor... | ['Animals', 'Ecology', 'Humans', 'Microbial Interactions', 'Microbiota', 'Systems Biology'] | 31,187,139 | [['B01.050'], ['H01.158.273.248', 'H01.277.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G06.550'], ['G06.591', 'G16.500.275.157.049.100.500', 'N06.230.124.049.100.500'], ['H01.158.273.180.800']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Arterial stiffness in children and adolescents with and without continuous insulin infusion. | Background Arterial stiffness is a consequence of aging, but there are several diseases that contribute to this process. The evaluation of pulse wave velocity (PWV) allows a dynamic evaluation of vascular distensibility and the detection of atherosclerosis at an early stage. It was intended to evaluate the PWV in child... | ['Adolescent', 'Adult', 'Atherosclerosis', 'Biomarkers', 'Blood Glucose', 'Child', 'Diabetes Mellitus, Type 1', 'Female', 'Follow-Up Studies', 'Glycated Hemoglobin A', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Insulin Infusion Systems', 'Male', 'Prognosis', 'Pulse Wave Analysis', 'Risk Factors', 'Vascular Stiffness'... | 31,228,861 | [['M01.060.057'], ['M01.060.116'], ['C14.907.137.126.307'], ['D23.101'], ['D09.947.875.359.448.500'], ['M01.060.406'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Brain glucagon-like peptide 1 signaling controls the onset of high-fat diet-induced insulin resistance and reduces energy expenditure. | Glucagon-like peptide-1 (GLP-1) is a peptide released by the intestine and the brain. We previously demonstrated that brain GLP-1 increases glucose-dependent hyperinsulinemia and insulin resistance. These two features are major characteristics of the onset of type 2 diabetes. Therefore, we investigated whether blocking... | ['Animals', 'Blood Glucose', 'Body Temperature Regulation', 'Brain Stem', 'Carbon Dioxide', 'Diabetes Mellitus, Type 2', 'Dietary Fats', 'Energy Metabolism', 'Glucagon-Like Peptide 1', 'Glucose Intolerance', 'Hyperinsulinism', 'Insulin Resistance', 'Ion Channels', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mitochondrial Pr... | 18,556,349 | [['B01.050'], ['D09.947.875.359.448.500'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['A08.186.211.132'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['C18.452.394.750.149', 'C19.246.300'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['G03.295'], ['D06.472.317.680.500.500'], ['C18.452.394.952.500... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 |
The Ultrastructural Relationship Between Osteocytes and Dental Implants Following Osseointegration. | BACKGROUND: Osteocytes, the most abundant cells in bone, have multiple functions, including acting as mechanosensors and regulating mineralization. It is clear that osteocytes influence bone remodeling by controlling the differentiation and activity of osteoblasts and osteoclasts. Determining the relationship between t... | ['Animals', 'Dental Implants', 'Female', 'Microscopy, Electron, Scanning', 'Osseointegration', 'Osteocytes', 'Rats', 'Rats, Sprague-Dawley', 'Surface Properties', 'Titanium'] | 25,039,329 | [['B01.050'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['G11.427.213.140.570', 'G16.762.150.150.570'], ['A11.329.629.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['G02.860'], ['D01.26... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Birth-season variation in Japanese macaques, Macaca fuscata. | Japanese macaques, Macaca fuscata, exhibit an annual reproductive cycle that apparently is maintained intrinsically. Translocation of nine troops to new latitudes within the northern hemisphere has had minimal effect on the timing of birth seasonality in these troops; translocation of one troop to the southern hemisphe... | ['Animals', 'Female', 'Geography', 'Japan', 'Macaca', 'Parturition', 'Pregnancy', 'Seasons', 'Time Factors'] | 12,687,474 | [['B01.050'], ['H01.277.500'], ['Z01.252.474.463', 'Z01.639.595'], ['B01.050.150.900.649.313.988.400.112.199.120.510'], ['G08.686.784.769.490'], ['G08.686.784.769'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['G01.910.857']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
All-cause mortality and cardiovascular effects associated with the DPP-IV inhibitor sitagliptin compared with metformin, a retrospective cohort study on the Danish population. | AIM: We performed a retrospective cohort study, investigating the clinical outcomes including mortality and cardiovascular disease of sitagliptin compared with metformin monotherapies.METHODS: All patients receiving monotherapy with the dipeptidyl peptidase-IV inhibitors (DPP-IV) inhibitor sitagliptin between 1 January... | ['Denmark', 'Diabetes Mellitus, Type 2', 'Diabetic Angiopathies', 'Dipeptidyl-Peptidase IV Inhibitors', 'Female', 'Humans', 'Hypoglycemic Agents', 'Male', 'Metformin', 'Middle Aged', 'Myocardial Infarction', 'Proportional Hazards Models', 'Pyrazines', 'Retrospective Studies', 'Sitagliptin Phosphate', 'Stroke', 'Treatme... | 24,020,750 | [['Z01.542.816.124'], ['C18.452.394.750.149', 'C19.246.300'], ['C14.907.320', 'C19.246.099.500'], ['D27.505.519.389.745.335', 'D27.505.696.422.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.422'], ['D02.078.370.141.450'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.35... | ['Geographicals [Z]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Impact of genetic merit for milk somatic cell score of sires and maternal grandsires on herd life of their daughters. | A retrospective study of the impact of the estimated breeding values of sires and maternal grandsires for somatic cell score (SCS) on productive life (PL) of Holsteins and Jerseys was conducted. Data included records from 2,626,425 Holstein and 142,725 Jersey cows. The sires and maternal grandsires of cows were require... | ['Animals', 'Breeding', 'Cattle', 'Dairying', 'Female', 'Lactation', 'Least-Squares Analysis', 'Male', 'Mastitis, Bovine', 'Milk', 'Retrospective Studies'] | 19,389,981 | [['B01.050'], ['E05.820.150', 'G05.090'], ['B01.050.150.900.649.313.500.380.271'], ['J01.040.246'], ['G08.686.523', 'G08.686.702.500'], ['E05.318.740.750.400', 'N05.715.360.750.695.440', 'N06.850.520.830.750.400'], ['C22.196.581'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Broadband ultrasound attenuation imaging: algorithm development and clinical assessment of a region growing technique. | This paper presents a computerized method for the selection of an irregular region of interest (ROI) in broadband ultrasound attenuation (BUA) images. A region growing algorithm searches an initial region in the posterior part of the calcaneus until the pixel with the lowest attenuation value is found; this is the star... | ['Algorithms', 'Case-Control Studies', 'Female', 'Femur', 'Hip Fractures', 'Humans', 'Postmenopause', 'ROC Curve', 'Ultrasonography'] | 11,837,620 | [['G17.035', 'L01.224.050'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A02.835.232.043.150'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.157.500.625', 'G08.686.841.249.500.625'], ['E05.318.370.800.750', 'E05.31... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Surgical treatment of patients with exudative otitis media]. | The article concerns peculiarities of surgery for chronic exudative otitis media (CEOM). The significance of miringotomy, tympanostomy, tympanotomy and tympanoantrotomy is demonstrated. The experience of the authors in surgical treatment and postoperative management of CEOM is reviewed. Of primary importance is valid s... | ['Chronic Disease', 'Follow-Up Studies', 'Humans', 'Middle Ear Ventilation', 'Otitis Media with Effusion', 'Otologic Surgical Procedures'] | 14,671,582 | [['C23.550.291.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.579.592', 'E04.580.450.472'], ['C09.218.705.663.670'], ['E04.580.450']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The clinical impact of echocardiography on antibiotic prophylaxis use in patients with suspected mitral valve prolapse. | PURPOSE: To determine the impact of echocardiography on the use of antibiotic prophylaxis in patients with suspected mitral valve prolapse (MVP).PATIENTS AND METHODS: We evaluated 147 consecutive patients who were referred for "rule out mitral valve prolapse" to a university hospital echocardiography laboratory. Chart ... | ['Adult', 'Antibiotic Prophylaxis', 'Echocardiography', 'Endocarditis, Bacterial', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mitral Valve Prolapse'] | 9,217,614 | [['M01.060.116'], ['E02.319.162.150', 'E02.319.703.150'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['C01.150.252.245', 'C01.190.249', 'C14.260.249', 'C14.280.282.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.484.400.500']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Free-living amoebae in Egypt. 1. Naegleria gruberi and Naegleria fowleri. | Two Naegleria species were isolated and identified from various water sources in Lower and Upper Egypt. Identification was based on the morphology, nuclear division and the excystation and flagellation tests. The trophic, cystic and flagellate forms of N. gruberi are larger than those of N. fowleri and the cyst of the ... | ['Animals', 'Egypt', 'Fresh Water', 'Naegleria'] | 2,033,306 | [['B01.050'], ['Z01.058.266.317'], ['G16.500.275.280', 'N06.230.232'], ['B01.046.500.700.710']] | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Occurrence of transient U-wave inversion during vasospastic anginal attack is not related to the direction of concurrent ST-segment shift. | STUDY OBJECTIVES: We sought to assess the incidence of transient U-wave inversion during vasospasm of the left anterior descending coronary artery (LAD) with ST-segment depression as opposed to that with ST-segment elevation.DESIGN: Retrospective study.SETTING: Cardiology division of acute-care hospitals.PATIENTS: We s... | ['Acetylcholine', 'Case-Control Studies', 'Collateral Circulation', 'Coronary Angiography', 'Coronary Circulation', 'Coronary Vasospasm', 'Electrocardiography', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Retrospective Studies'] | 12,171,828 | [['D02.092.211.111'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G09.330.100.248'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['G09.330.100.324'], ['C14.280.647.250.295', 'C14.907.585.250.295'], ['E01.370.370.380.240', 'E01.37... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Is it necessary to treat the autonomous thyroid adenoma?]. | A treatment of the autonomous nodule in an euthyroid patient is still in question. We therefore compared our findings in treated and untreated patients with this disease. Pooling all datas of untreated patients, one got worse in 84 observed years while one got completely normal in 67 years. None of the 16 patients expo... | ['Adenoma', 'Dose-Response Relationship, Drug', 'Humans', 'Hyperthyroidism', 'Iodine Radioisotopes', 'Thyroid Hormones', 'Thyroid Neoplasms', 'Thyroidectomy'] | 7,231,333 | [['C04.557.470.035'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.397'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['D06.472.931'], ['C04.588.322.894', 'C04.588.443.915', 'C19.344.894', 'C19.874.788'], ['E04.270.856']] | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Intraparenchymal cerebral hemorrhage and cocaine]. | Medical problems related to cocaine consumption are not rare in our environment; however, to this respect, descriptions in the spanish literature are scarce. We present three cases of intracerebral hemorrhage which occurred after cocaine consumption (intranasal route in two cases and intravenous route in one case). In ... | ['Adult', 'Cerebral Hemorrhage', 'Cocaine', 'Humans', 'Male', 'Substance-Related Disorders'] | 1,623,099 | [['M01.060.116'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C25.775', 'F03.900']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Experiences with intended dynamic group psychotherapy in the complex therapy of schizophrenic patients]. | Intention, setting (6 weeks intensive therapy, 2 years follow meetings) and premise for a integration of dynamic intended group psychotherapy (H ? c k) of schizophrenics in a psychiatric ward are discussed. The attitude of both therapeuts intending phases of group process hat to be taken into account as for the transfe... | ['Adult', 'Chronic Disease', 'Combined Modality Therapy', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Psychiatric Department, Hospital', 'Psychoanalytic Therapy', 'Psychotherapy, Group', 'Schizophrenia', 'Schizophrenic Psychology', 'Social Adjustment'] | 3,588,762 | [['M01.060.116'], ['C23.550.291.500'], ['E02.186'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N02.278.216.500.968.641', 'N04.452.442.452.422.641'], ['F04.754.709'], ['F04.754.864.581'], ['F03.700.750... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Visiting the Operating Theatre Before Surgery Did Not Reduce the Anxiety in Children and Their Attendant Parent. | PURPOSE: The induction of anesthesia is known to be the most stressful part of the day of surgery for the child. Non-pharmacologic intervention is a field of great interest. The aims of this prospective randomized study were to evaluate if (1). A preoperative visit to the operating theatre would attenuate the anxiety o... | ['Adaptation, Psychological', 'Adult', 'Age Factors', 'Analysis of Variance', 'Anxiety', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Operating Rooms', 'Parents', 'Patient Education as Topic', 'Preoperative Period', 'Prospective Studies', 'Reference Values', 'Risk Assessment', 'Sex Factors', 'Statistics, N... | 28,939,000 | [['F01.058'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F01.470.132'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.700'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.6... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Damage and repair of the immature rat cerebellum after cis-dichlorodiammineplatinum II (cis-DDP) treatment. An ultrastructural study. | The aim of this electron microscopy study was to further investigate the effects of cis-dichlorodiammineplatinum (cis-DDP) on the cerebellum of the immature rat. Ten-day-old animals were treated with cis-DDP subcutaneously and killed after 1, 7, 15 or 21 days. On postinjection day 1, cis-DDP effects were evident mainly... | ['Animals', 'Cerebellum', 'Cisplatin', 'Microscopy, Electron', 'Rats', 'Rats, Inbred Strains', 'Time Factors'] | 3,564,902 | [['B01.050'], ['A08.186.211.132.810.428.200'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E01.370.350.515.402', 'E05.595.402'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['G01.910.857']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Coloration variability of the Oriental genus Agnorimus Miyake amp; Iwase, 1991 (Coleoptera: Scarabaeidae, Cetoniinae) with synonymic notes. | Based on an examination of a large number of specimens, considerable variability of the elytral coloration patterns and the parameres of the Asian genus Agnorimus Miyake Iwase, 1991 are observed; and the taxonomic status of all four described taxa have been re-considered. The result shows that only A. pictus (Moser, 19... | ['Animal Distribution', 'Animal Structures', 'Animals', 'Coleoptera'] | 31,716,160 | [['F01.145.113.069', 'G16.049'], ['A13'], ['B01.050'], ['B01.050.500.131.617.720.500.500.375']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diphenyleneiodonium enhances oxidative stress and inhibits Japanese encephalitis virus induced autophagy and ER stress pathways. | Diphenyleneiodonium (DPI) and N-acetyl-l-cysteine (NAC), two widely used anti-oxidants, were employed to evaluate the role of oxidative stress in Japanese encephalitis virus (JEV) induced autophagy, stress responses and replication. DPI and NAC exerted opposite effects on ROS levels in JEV infected mouse neuronal cells... | ['Acetylcysteine', 'Animals', 'Antioxidants', 'Autophagy', 'Cells, Cultured', 'Encephalitis Virus, Japanese', 'Endoplasmic Reticulum Stress', 'HeLa Cells', 'Humans', 'Mice', 'Onium Compounds', 'Oxidative Stress', 'Swine', 'Virus Replication'] | 29,792,860 | [['D02.886.030.230.259', 'D12.125.166.230.259'], ['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G04.011'], ['A11.251'], ['B04.820.230.475.227', 'B04.820.578.344.350.300.227'], ['G04.434'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adsorption-regeneration by heterogeneous Fenton process using modified carbon and clay materials for removal of indigo blue. | Indigo blue dye is mainly used in dyeing of denim clothes and its presence in water bodies could have adverse effects on the aquatic system; for this reason, the objective of this study was to promote the removal of indigo blue dye from aqueous solutions by iron and copper electrochemically modified clay and activated ... | ['Adsorption', 'Aluminum Silicates', 'Bentonite', 'Carbon', 'Charcoal', 'Clay', 'Hydrogen Peroxide', 'Indigo Carmine', 'Iron', 'Water Pollutants, Chemical', 'Water Purification'] | 26,878,687 | [['G01.030', 'G02.020'], ['D01.056.050.075', 'D01.578.725.025', 'D01.650.550.050.075', 'D01.837.725.700.760.050'], ['D01.056.050.075.100', 'D01.578.725.025.100', 'D01.650.550.050.075.100', 'D01.837.725.700.760.050.100'], ['D01.268.150'], ['D01.268.150.150'], ['D20.721.250', 'G01.311.820.250', 'G16.500.275.815.250', 'N0... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Outcomes of patients with periprocedural atrial fibrillation undergoing percutaneous coronary intervention for chronic total occlusion. | BACKGROUND: Successful CTO recanalization has been associated with clinical benefit. Outcomes of patients with atrial fibrillation undergoing CTO PCI have not been investigated, yet.AIMS: This study sought to evaluate the association between atrial fibrillation and outcomes after percutaneous coronary intervention (PCI... | ['Aged', 'Atrial Fibrillation', 'Chronic Disease', 'Coronary Angiography', 'Coronary Occlusion', 'Female', 'Follow-Up Studies', 'Germany', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Percutaneous Coronary Intervention', 'Registries', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors', 'Survival Rate', 'Time ... | 28,776,267 | [['M01.060.116.100'], ['C14.280.067.198', 'C23.550.073.198'], ['C23.550.291.500'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250.272', 'C14.907.585.250.272'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Backbone and side-chain 1 | The bacterium Staphylococcus aureus produces an array of anti-inflammatory molecules that prevent the innate immune system from recognizing it as a pathogen and clearing it from the host. In the acute phase of inflammation, our immune system relies on neutrophils to clear invading bacteria. Recently, novel classes of s... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Enzyme Inhibitors', 'Nuclear Magnetic Resonance, Biomolecular', 'Peroxidase', 'Staphylococcus aureus'] | 28,815,423 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['D27.505.519.389'], ['E05.196.867.519.550'], ['D08.811.682.732.700'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.510.100.750.750.100', 'B03.510.400.790.750.100']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The ultrastructure of isolated rat oligodendroglial cell cultures. | Cultured rat oligodendrocytes were studied by transmission electron microscopy. Cells were identified by an immunocytochemical stain for galactocerebroside, a specific cell surface marker for oligodendroglial cells. Oligodendroglial cell perikarya contained numerous ribosomal rosettes, microtubules, prominent networks ... | ['Animals', 'Cells, Cultured', 'Galactosylceramides', 'Immunoenzyme Techniques', 'Intercellular Junctions', 'Microscopy, Electron', 'Neuroglia', 'Oligodendroglia', 'Rats', 'Rats, Inbred Strains'] | 6,759,622 | [['B01.050'], ['A11.251'], ['D02.065.313.250.450', 'D09.400.410.420.525.200.250.450', 'D10.390.470.675.200.250.450', 'D10.570.877.360.612.200.250.450'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['A11.284.149.165.420'], ['E01.370.350.515.402', 'E05.595.402'], ['A08.637', 'A11.650'], ['A08.637.600', 'A1... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of opioid antagonists and their quaternary derivatives on locomotor activity and fixed ratio responding for brain self-stimulation in rats. | Rats were implanted with stimulating electrodes aimed at the midbrain-central gray area (MID-CG) and trained to lever press for brain stimulation (ICSS) on a fixed ratio:30 (FR:30) schedule of reinforcement. When response rates were stable, animals were administered either naloxone hydrochloride, naltrexone hydrochlori... | ['Animals', 'Brain Mapping', 'Conditioning, Operant', 'Male', 'Mesencephalon', 'Motor Activity', 'Naloxone', 'Naltrexone', 'Narcotic Antagonists', 'Rats', 'Rats, Inbred Strains', 'Reinforcement Schedule', 'Self Stimulation'] | 4,080,766 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.425.179.509'], ['A08.186.211.132.659'], ['F01.145.632', 'G11.427.410.698'], ['D03.132.577.249.706', 'D03.605.497.750', 'D03.633.400.686.750', 'D04.615.723.795.706'], ['D03.132.577.249.706.550', 'D03.605.497.750.550', 'D03... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficient CRISPR/Cas9 Disruption of Autoimmune-Associated Genes Reveals Key Signaling Programs in Primary Human T Cells. | Risk of autoimmunity is associated with multiple genetic variants. Genome-wide association studies have linked single-nucleotide polymorphisms in the phosphatases PTPN22 (rs2476601) and PTPN2 (rs1893217) to increased risk for multiple autoimmune diseases. Previous mouse studies of loss of function or risk variants in t... | ['Alleles', 'Autoimmunity', 'Blood Donors', 'CD4-Positive T-Lymphocytes', 'CRISPR-Cas Systems', 'Cells, Cultured', 'Gene Editing', 'Genome-Wide Association Study', 'Humans', 'Interleukin-2', 'Phenotype', 'Polymorphism, Single Nucleotide', 'Protein Tyrosine Phosphatase, Non-Receptor Type 2', 'Protein Tyrosine Phosphatas... | 31,722,988 | [['G05.360.340.024.340.030'], ['G12.450.192'], ['M01.898.313'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['G05.308.203.374.394'], ['A11.251'], ['E05.393.420.270'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500'... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Matrilin-2 is proteolytically cleaved by ADAMTS-4 and ADAMTS-5. | Matrilin-2 is a widely distributed, oligomeric extracellular matrix protein that forms a filamentous network by binding to a variety of different extracellular matrix proteins. We found matrilin-2 proteolytic products in transfected cell lines in vitro and in mouse tissues in vivo. Two putative cleavage sites were iden... | ['ADAM Proteins', 'ADAMTS4 Protein', 'ADAMTS5 Protein', 'Animals', 'COS Cells', 'Cell Line', 'Chlorocebus aethiops', 'Extracellular Matrix', 'Humans', 'Matrilin Proteins', 'Mice', 'Procollagen N-Endopeptidase', 'Proteolysis', 'Transfection'] | 24,959,676 | [['D08.811.277.656.675.374.102', 'D09.400.430.500', 'D12.776.395.033'], ['D08.811.277.656.675.374.102.500.844', 'D09.400.430.500.500.844', 'D12.776.395.033.500.844', 'D12.776.860.300.085.844'], ['D08.811.277.656.675.374.102.500.875', 'D09.400.430.500.500.875', 'D12.776.395.033.500.875', 'D12.776.860.300.085.875'], ['B0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
zTrap: zebrafish gene trap and enhancer trap database. | BACKGROUND: We have developed genetic methods in zebrafish by using the Tol2 transposable element; namely, transgenesis, gene trapping, enhancer trapping and the Gal4FF-UAS system. Gene trap constructs contain a splice acceptor and the GFP or Gal4FF (a modified version of the yeast Gal4 transcription activator) gene, a... | ['Animals', 'Animals, Genetically Modified', 'DNA Transposable Elements', 'Databases, Genetic', 'Enhancer Elements, Genetic', 'Gene Expression Regulation, Developmental', 'Genes, Reporter', 'Green Fluorescent Proteins', 'Software', 'Transgenes', 'Zebrafish'] | 20,950,494 | [['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['G02.111.570.080.689.330', 'G05.360.080.689.330', 'G05.360.340.024.340.137.750.249'], ['G05.308.310'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Histologic evaluation of intraoral skin grafts and pedicle flaps in humans. | Histologic evaluation of biopsy specimens from six split-thickness skin grafts and seven pedicle flaps was made two months to 15 years after intraoral cancer reconstruction. In the transplanted skin, there was persistence of all epidermal layers with production of orthokeratin and melanin, and persistence of papillary ... | ['Follow-Up Studies', 'Humans', 'Keratins', 'Melanins', 'Mouth Mucosa', 'Skin', 'Skin Transplantation', 'Sweat Glands', 'Transplantation, Autologous'] | 781,193 | [['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.593.450', 'D12.776.220.475.450', 'D12.776.860.607'], ['D12.125.072.050.875.379', 'D23.767.620'], ['A10.615.550.599', 'A14.549.512'], ['A17.815'], ['E02.095.147.725.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Autoradiographic localization of technetium-99 methylene diphosphonate in growth sites of young mice. | Conflicting reports about the localization of 99mTc-MDP in bone and cartilage are found in the literature. Possible binding sites include hydroxyapatite and non-osteoid matrix such as immature collagen. The present study used autoradiographs of demineralized and non-demineralized growth sites in young mice to demonstra... | ['Animals', 'Autoradiography', 'Bone Development', 'Calcification, Physiologic', 'Growth Plate', 'Mandibular Condyle', 'Mice', 'Technetium Tc 99m Medronate'] | 3,366,618 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['G07.345.500.325.377.625.050.500', 'G11.427.578.050.500'], ['G07.345.155.500', 'G07.345.500.325.377.625.050.500.175', 'G11.427.578.050.500.175'], ['A02.835.232.251.352'], ['A02.835.232.781.324.502.632.600', 'A14.521.632.600'], ['B01.050.150.900.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[New insights into the seriousness of acute myocardial injury during COVID-19]. | Retrospective data from Chinese cohorts published in the last few days have placed a strong emphasis on the possibility that acute myocardial injury represents a critical component in the development of serious complications in patients hospitalized with COVID-19. These analyses showed that 19-27% of hospitalized patie... | ['Betacoronavirus', 'COVID-19', 'Coronavirus Infections', 'Critical Illness', 'Humans', 'Myocardial Infarction', 'Pandemics', 'Pneumonia, Viral', 'SARS-CoV-2'] | 32,310,916 | [['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['C01.925.782.600.550.200'], ['C23.550.291.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.280.647.500', 'C14.907.585.500... | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Capnography and respiratory depression. | In order to determine whether opioid-naive patients at risk for respiratory depression are better monitored with either capnography or pulse oximetry and respiratory-rate assessment, the authors conducted a randomized, prospective trial. In 54 opioid-naive postoperative orthopedic patients at one hospital, capnography ... | ['Aged', 'Analgesics, Opioid', 'Capnography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Orthopedic Procedures', 'Pain, Postoperative', 'Prospective Studies', 'Respiratory Insufficiency', 'Risk Factors', 'Sensitivity and Specificity', 'Sleep Apnea, Obstructive'] | 18,227,667 | [['M01.060.116.100'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E01.370.386.700.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.718', 'E04.555'], ['C23.550.767.700', 'C23.888.592.612.832'], ['E05.318... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bioactivation of flavonoid diglycosides by chicken cecal bacteria. | Flavonoids, the potent antioxidant and anti-inflammatory plant compounds, require deglycosylation for absorption across the intestine. Intestinal bacteria are indispensable for the hydrolysis of flavonoid diglycosides. We isolated, for the first time, three anaerobic Lactobacillus-like strains designated as MF-01, MF-0... | ['Animals', 'Biotransformation', 'Carboxylic Acids', 'Cecum', 'Chickens', 'Cluster Analysis', 'DNA, Bacterial', 'DNA, Ribosomal', 'Flavanones', 'Flavonoids', 'Hesperidin', 'Lactobacillus', 'Maltose', 'Molecular Sequence Data', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Rutin', 'Sequence Analysis, DNA', 'Sequence Homology, Nu... | 19,473,248 | [['B01.050'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['D02.241'], ['A03.556.124.526.209', 'A03.556.249.249.209'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['D13.444.308.212'], ['D13.444.308.475'], ['D03.383.663.283.266.450... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Perifosine as potential anti-cancer agent inhibits proliferation, migration, and tube formation of human umbilical vein endothelial cells. | Targeting angiogenesis is considered an effective strategy for treating the expansion and metastasis of tumors. The aim of this study is to assess the effects of perifosine, an inhibitor of Akt, on cell proliferation, apoptosis, angiogenesis, and VEGF-induced cell migration in cultured human umbilical vein endothelial ... | ['Antineoplastic Agents', 'Cell Line', 'Cell Movement', 'Cyclin B1', 'G2 Phase', 'Human Umbilical Vein Endothelial Cells', 'Humans', 'Neovascularization, Pathologic', 'Phosphorylation', 'Phosphorylcholine', 'Proto-Oncogene Proteins c-akt', 'Vascular Endothelial Growth Factor A', 'p38 Mitogen-Activated Protein Kinases'] | 21,769,450 | [['D27.505.954.248'], ['A11.251.210'], ['G04.198', 'G07.568.500.180'], ['D12.644.360.262.120.100', 'D12.776.167.218.120.100', 'D12.776.476.262.120.100'], ['G04.144.500.340'], ['A11.436.275.682'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.589.500'], ['G02.111.665', 'G02.607.780', 'G03.796'], ['D02.092.8... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The currently available possibilities for fixation of many-layer transplants in myringoplasty]. | The objective of the present study was to improve the quality and efficacy of the surgical treatment of chronic otitis media including the plastic correction of total and subtotal tympanic defects by fixing a many-layer chondro-perichondrial autograft with the use of a latex tissue glue. Twenty seven patients presentin... | ['Adhesives', 'Cartilage', 'Hearing Tests', 'Humans', 'Latex', 'Length of Stay', 'Myringoplasty', 'Postoperative Complications', 'Surgical Flaps', 'Transplantation, Autologous', 'Transplants', 'Treatment Outcome', 'Tympanic Membrane', 'Tympanic Membrane Perforation'] | 23,011,372 | [['D27.720.013', 'J01.637.016'], ['A02.165', 'A10.165.382'], ['E01.370.382.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.625', 'D20.215.721.124', 'D25.720.099.625', 'D25.720.099.750.500', 'D25.720.327.840.239', 'J01.637.051.720.099.625', 'J01.637.051.720.540'], ['E02.760.400.480', 'N02.421.585.4... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Far-field auditory brainstem response in neurotologic surgery. | This is a review of our experience using far-field auditory brainstem monitoring during acoustic neuroma removal. The observations are based on 144 consecutive cases beginning in 1986. The factors of importance are tumor size, preoperative auditory function, and the preoperative presence of a wave V on the auditory bra... | ['Adolescent', 'Adult', 'Aged', 'Cochlea', 'Cranial Nerve Neoplasms', 'Evoked Potentials, Auditory, Brain Stem', 'Female', 'Hearing', 'Humans', 'Male', 'Middle Aged', 'Monitoring, Intraoperative', 'Neuroma, Acoustic', 'Vestibulocochlear Nerve'] | 8,694,121 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A09.246.300.246'], ['C04.588.614.300', 'C04.588.614.596.240', 'C10.292.225', 'C10.551.360', 'C10.551.775.250'], ['G07.265.216.500.370.300', 'G07.888.250.300', 'G11.561.200.500.370.300'], ['F02.830.816.263', 'G07.888.500', 'G11.561.790.263'], ['B01.050.150.900.64... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Routine Virtual Ileostomy Following Restorative Proctocolectomy for Familial Adenomatous Polyposis. | BACKGROUND: Anastomotic leakage (AL) is the most feared complication in colorectal surgery. A diverting ileostomy is routinely used to prevent or reduce morbidity and mortality following AL. However, a diverting ileostomy cannot prevent AL. Besides, diverting ileostomy might be associated with relevant complications. H... | ['Adenomatous Polyposis Coli', 'Adolescent', 'Adult', 'Anastomotic Leak', 'Female', 'Humans', 'Ileostomy', 'Male', 'Proctocolectomy, Restorative'] | 29,147,895 | [['C04.557.470.035.215.100', 'C04.588.274.476.411.307.089', 'C04.700.100', 'C06.301.371.411.307.090', 'C06.405.249.411.307.090', 'C06.405.469.158.356.090', 'C06.405.469.491.307.090', 'C06.405.469.578.249', 'C16.320.700.100'], ['M01.060.057'], ['M01.060.116'], ['C23.550.767.071'], ['B01.050.150.900.649.313.988.400.112.4... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Central nervous system involvement in HCV-related mixed cryoglobulinemia. | An involvement of the peripheral nervous system is frequent in patients with HCV-related mixed cryoglobulinemia (HCV-MC), whereas central nervous system (CNS) impairment has been rarely reported. To investigate the possible CNS involvement in MC, we evaluated 18 patients by neurophysiological, neuroradiological and neu... | ['Aged', 'Antibodies, Monoclonal', 'Atrophy', 'Attention', 'Brain', 'Central Nervous System Diseases', 'Cognition Disorders', 'Cryoglobulinemia', 'Electromyography', 'Evoked Potentials, Auditory, Brain Stem', 'Evoked Potentials, Motor', 'Evoked Potentials, Somatosensory', 'Evoked Potentials, Visual', 'Female', 'Hepatit... | 16,918,199 | [['M01.060.116.100'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['C23.300.070'], ['F02.830.104.214'], ['A08.186.211'], ['C10.228'], ['F03.615.250'], ['C14.907.454.140', 'C15.378.147.780.243', 'C15.378.463.515.140', 'C20.683.780.250'], ['E01.370.405.255', 'E01.370.530... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Increase of the apnoea-hypopnoea index after uvulopalatopharyngoplasty: analysis of failure. | From 70 patients who had uvulopalatopharyngoplasty (UPPP) operation and a pre- and postoperative sleep registration, we could retrospectively determine the failures and the correlation between variables such as age, gender, body mass index (BMI), earlier or concomitant tonsillectomy, unilevel (uvula-palate-tonsil) or m... | ['Adult', 'Body Mass Index', 'Electroencephalography', 'Electromyography', 'Eye Movements', 'Female', 'Humans', 'Male', 'Middle Aged', 'Otorhinolaryngologic Surgical Procedures', 'Palate, Soft', 'Postoperative Care', 'Postoperative Complications', 'Preoperative Care', 'Retrospective Studies', 'Severity of Illness Index... | 15,533,159 | [['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E01.370.376.300', 'E01.370.405.245'], ['E01.370.405.255', 'E01.370.530.255'], ['G11.427.410.140', 'G14.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.580'], ['A14.549.617... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Antibodies to human herpes virus-6 in patients with acute lymphocytic leukemia. | Human herpesvirus-6 (HHV-6), a ubiquitous virus that causes exanthem subitum and occasional cases of infectious mononucleosis, hepatitis and other viral syndromes, has also been associated with acute lymphocytic leukemia (ALL) in children. To further investigate this association, we obtained sera from 50 patients with ... | ['Adolescent', 'Adult', 'Antibodies, Viral', 'Child', 'Child, Preschool', 'Female', 'Herpesviridae Infections', 'Herpesvirus 6, Human', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Precursor Cell Lymphoblastic Leukemia-Lymphoma'] | 1,331,626 | [['M01.060.057'], ['M01.060.116'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['M01.060.406'], ['M01.060.406.448'], ['C01.925.256.466'], ['B04.280.382.150.750.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['C04.557.337.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dissipation of metabolic heat in the horse during exercise. | Horses were exercised at 40, 65, and 90% of their maximum O2 uptake (VO2max) until moderately fatigued (approximately 38, 15, and 9 min, respectively) to assess heat loss through different routes. Approximately 4,232, 3,195, and 2,333 kcal of heat were generated in response to exercise at these intensities. Of this, ap... | ['Animals', 'Blood Physiological Phenomena', 'Body Temperature Regulation', 'Body Weight', 'Cardiac Output', 'Horses', 'Muscles', 'Oxygen Consumption', 'Physical Exertion', 'Pulmonary Circulation', 'Rectum', 'Skin Temperature', 'Sweating'] | 8,482,654 | [['B01.050'], ['G09.188'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E01.370.370.380.150', 'G09.330.380.124'], ['B01.050.150.900.649.313.984.235.472'], ['A02.633', 'A10.690'], ['G03.680'], ['G... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Estimating disease burden of maternal syphilis and associated adverse pregnancy outcomes in India, Nigeria, and Zambia in 2012. | OBJECTIVE: To estimate maternal syphilis and its associated adverse pregnancy outcomes in India, Nigeria, and Zambia.METHODS: An online estimation tool was used to generate point estimates and uncertainty ranges of maternal syphilis and adverse pregnancy outcomes due to mother-to-child transmission (MTCT). The most rec... | ['Adult', 'Cost of Illness', 'Female', 'Humans', 'India', 'Infant, Newborn', 'Infectious Disease Transmission, Vertical', 'Nigeria', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Pregnancy Outcome', 'Seroepidemiologic Studies', 'Syphilis', 'Zambia'] | 25,975,870 | [['M01.060.116'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['M01.060.703.520'], ['N06.850.335.875'], ['Z01.058.290.190.565'], ['G08.686.784.769'], ['C01.674', 'C13.703.700'], ['E01.789.700', 'G08.686.... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
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