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Differential interleukin-1 receptor antagonism on pancreatic beta and alpha cells. Studies in rodent and human islets and in normal rats. | The monokines interleukin-1 alpha and -beta have been implicated as effector molecules in the immune-mediated pancreatic beta-cell destruction leading to insulin-dependent diabetes mellitus. Here we investigated the effects of interleukin-1 receptor antagonism on insulin and glucagon release of rat, mouse and human isl... | ['Animals', 'Antibodies', 'Cells, Cultured', 'Glucose', 'Humans', 'Insulin', 'Insulin Secretion', 'Interleukin-1', 'Islets of Langerhans', 'Kinetics', 'Lymphocyte Activation', 'Male', 'Mice', 'Mice, Inbred C3H', 'Rats', 'Rats, Wistar', 'Receptors, Interleukin-1', 'Recombinant Proteins', 'T-Lymphocytes', 'Thymus Gland'] | 8,405,744 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['A11.251'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.442', 'G07.475'], ['D12.644.276.374.465.010', 'D12.644.276.374.500... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Binding of HIV-1 to RBCs involves the Duffy antigen receptors for chemokines (DARC). | The Duffy Antigen Receptor for Chemokines (DARC) belongs to a family of erythrocyte chemokine receptors that bind C-X-C and C-C chemokines such as interleukin 8 (IL-8), monocyte chemoattractant protein 1 (MCP-1) and regulated-on-activation, normal T cell-expressed and -secreted (RANTES), but not macrophage inflammatory... | ['Antigens, Protozoan', 'Carrier Proteins', 'Chemokines', 'Duffy Blood-Group System', 'Enzyme-Linked Immunosorbent Assay', 'Erythrocytes', 'HIV-1', 'Humans', 'In Vitro Techniques', 'Protozoan Proteins', 'Receptors, Antigen', 'Receptors, Cell Surface'] | 9,921,412 | [['D23.050.293'], ['D12.776.157'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['D23.050.301.290.301', 'D23.050.705.230.301'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['A11.118.290', 'A11.44... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
MicroRNA profiling of low-grade and transformed nodal marginal zone lymphoma reveals a similar signature pattern distinct from diffuse large B cell lymphoma. | BACKGROUND/AIMS: As critical post-transcriptional regulators of gene expression, microRNAs are involved in several cellular processes of vital impact including cell growth and apoptosis. Many hematologic malignancies exhibit distinct microRNA signatures. MicroRNA implication in the pathogenesis of nodal marginal zone l... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lymph Nodes', 'Lymphoma, B-Cell, Marginal Zone', 'Lymphoma, Large B-Cell, Diffuse', 'Male', 'MicroRNAs', 'Middle Aged', 'RNA, Neoplasm', 'Retrospective Studies'] | 25,376,122 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.393.332'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.549.400', 'A15.382.520.604.412'], ['C04.557.386.480.150.570', 'C15.604.515.569.480.150.570', 'C20.683.515.761.480.150.570'], ['C04.557.386.480.150.585', 'C15.604.515.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Probing the Molecular Structure and Orientation of the Leaf Surface of Brassica oleracea L. by Polarization Modulation-Infrared Reflection-Absorption Spectroscopy. | The surface of most aerial plant organs is covered with the cuticle, a membrane consisting of a variety of organic compounds, including waxes, cutin (a polyester) and polysaccharides. The cuticle serves as the multifunctional interface between the plant and the environment, and plays a major role in protecting plants a... | ['Brassica', 'Glucans', 'Membrane Lipids', 'Plant Epidermis', 'Plant Leaves', 'Spectroscopy, Near-Infrared', 'Xylan Endo-1,3-beta-Xylosidase', 'Xylans'] | 31,020,320 | [['B01.650.940.800.575.912.250.157.200'], ['D05.750.078.562', 'D09.698.365'], ['D10.570'], ['A18.024.750'], ['A18.024.812'], ['E01.370.350.750', 'E05.196.867.851'], ['D08.811.277.450.950.500'], ['D09.698.925']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A European multicientre study on the comparison of HBV viral loads between VERIS HBV assay and Roche COBAS® | BACKGROUND: Hepatitis B viral load testing is essential to treatment and monitoring decisions in patients with chronic Hepatitis B. Beckman Coulter has developed the VERIS HBV Assay (Veris) for use on the fully automated DxN VERIS Molecular Diagnostics System.1 OBJECTIVES: To evaluate the clinical performance of the Ve... | ['DNA, Viral', 'Europe', 'Hepatitis B virus', 'Hepatitis B, Chronic', 'Humans', 'Polymerase Chain Reaction', 'Reagent Kits, Diagnostic', 'Sensitivity and Specificity', 'Serologic Tests', 'Viral Load'] | 28,892,764 | [['D13.444.308.568'], ['Z01.542'], ['B04.280.375.650.425', 'B04.450.390.650.425'], ['C01.221.250.500.100', 'C01.925.256.430.400.100', 'C01.925.440.435.100', 'C06.552.380.350.100', 'C06.552.380.705.437.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.393.620.500'], ['D27.505.259.875', 'D27.720.470.410.680',... | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Restaurant Inspection Reports as a Proxy Measure for Occupational Health and Safety: South Asian Restaurant Workers in New York City. | There is a great need to develop workplace health and safety surveillance systems for small businesses to systematically understand the cause, nature, and severity of injuries and illness of their workers. Restaurants can be hazardous workplaces for the nature of the business, materials handled, and tasks completed. So... | ['Asian Continental Ancestry Group', 'Bangladesh', 'Emigrants and Immigrants', 'European Continental Ancestry Group', 'Humans', 'India', 'New York City', 'Occupational Health', 'Pakistan', 'Public Health Surveillance', 'Restaurants', 'United States', 'United States Occupational Safety and Health Administration'] | 30,835,402 | [['M01.686.508.200'], ['Z01.252.245.131'], ['M01.189'], ['M01.686.508.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['Z01.107.567.875.350.530.530', 'Z01.107.567.875.500.530.530', 'Z01.433.741'], ['N01.400.525'], ['Z01.252.245.723'], ['E05.318.308.980.438.700.324', 'N05.715.360.300.800.438... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Frequent K-ras mutations and absence of p53 mutations in mucin-producing tumors of the pancreas. | Mucin-producing tumors of the pancreas (MPT) are characterized by the production of much mucin and a benign course after surgical treatment. We examined 16 cases of MPT and 20 cases of "common" pancreatic duct cell carcinomas (DCC) in regard to K-ras and p53 mutations. The mutations were detected by constant denaturant... | ['Adenocarcinoma, Mucinous', 'Adenoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Base Sequence', 'Carcinoma, Intraductal, Noninfiltrating', 'Female', 'Genes, p53', 'Genes, ras', 'Humans', 'Male', 'Middle Aged', 'Molecular Sequence Data', 'Mucins', 'Mutation', 'Pancreatic Neoplasms', 'Polymerase Chain Reaction'] | 8,121,190 | [['C04.557.470.200.025.075', 'C04.557.470.590.075'], ['C04.557.470.035'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.557.470.200.025.275', 'C04.557.470.200.240.187.250', 'C04.557.470.615.275'], ['G05.360.340.024.340.375.249.385', 'G05.... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
An Australian survey of in-patient protocols for quadriceps exercises following anterior cruciate ligament reconstruction. | Current practices regarding in-patient strengthening exercise prescription following anterior cruclate ligament (ACL) reconstruction are scarcely addressed in the literature and remain unreported for Australian hospitals. An observational, questionnaire-based study was used to Investigate in-patient quadriceps strength... | ['Anterior Cruciate Ligament', 'Anterior Cruciate Ligament Injuries', 'Australia', 'Biomechanical Phenomena', 'Exercise Therapy', 'Humans', 'Inpatients', 'Muscle, Skeletal', 'Range of Motion, Articular', 'Rehabilitation', 'Surveys and Questionnaires'] | 12,585,612 | [['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['C26.558.554.213'], ['Z01.639.100', 'Z01.678.100.373'], ['G01.154.090', 'G01.374.089'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['A02.633.567', 'A10.690.552.500']... | ['Anatomy [A]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Enhanced production of artemisinin by hairy root cultivation of Artemisia annua in a modified stirred tank reactor. | Artemisinin is an important drug commonly used in the treatment of malaria as a combination therapy. It is primarily produced by a plant Artemisia annua, however, its supply from plant is significantly lower than its huge demand and therefore alternative in vitro production routes are sought. Hairy root cultivation cou... | ['Acetates', 'Artemisia annua', 'Artemisinins', 'Bioreactors', 'Culture Techniques', 'Cyclopentanes', 'Kinetics', 'Oxygen', 'Oxylipins', 'Plant Roots'] | 25,172,060 | [['D02.241.081.018', 'D10.251.400.045'], ['B01.650.940.800.575.912.250.100.100.144'], ['D01.248.497.158.685.750.212', 'D01.339.431.374.212', 'D01.650.550.750.200', 'D02.389.338.055', 'D02.455.849.765.211'], ['E07.115', 'J01.897.120.115'], ['E05.481.500'], ['D02.455.426.392.368.450'], ['G01.374.661', 'G02.111.490'], ['D... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Validation of a septic myocardial inhibition model by intraperitoneal injection of endotoxin in rats]. | OBJECTIVE: To establish septic myocardial inhibition rat model by echocardiography.METHODS: Twenty adult male Sprague-Dawley (SD) rats were divided into control group and model group according to the random number table method, with 10 rats in each group. The rat model of septic myocardial inhibition was reproduced by ... | ['Animals', 'Endotoxins', 'Injections, Intraperitoneal', 'Male', 'Models, Animal', 'Myocardium', 'NF-kappa B', 'Rats', 'Rats, Sprague-Dawley', 'Tumor Necrosis Factor-alpha'] | 31,537,226 | [['B01.050'], ['D23.946.123.329'], ['E02.319.267.530.490'], ['E05.598'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D05.500.672', 'D12.776.260.600', 'D12.776.660.600', 'D12.776.930.600'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['D12.644.276.374.500.800', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Surgical correction of intrathoracic compression of respiratory ways due to double aortal arch in children]. | In 1982-1999 period 49 children aged 1.5 mo-14 yrs with vascular ring anomaly were examined. In 28 of them the double aortal arch (DAA), causing intrathoracic compression of respiratory ways, was revealed. Surgical correction of DAA was done in 27 patients. Optimal surgical access is left-sided lateral thoracotomy alon... | ['Adolescent', 'Airway Obstruction', 'Aorta, Thoracic', 'Child', 'Child, Preschool', 'Decompression, Surgical', 'Female', 'Humans', 'Infant', 'Male', 'Respiratory Tract Diseases', 'Retrospective Studies', 'Tracheal Diseases', 'Treatment Outcome'] | 11,288,274 | [['M01.060.057'], ['C08.618.846.185'], ['A07.015.114.056.372'], ['M01.060.406'], ['M01.060.406.448'], ['E04.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C08'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enhancement of dengue virus translation: role of the 3' untranslated region and the terminal 3' stem-loop domain. | An essential step for a productive infection by the dengue flavivirus (DEN) is translation of the m(7)G-capped, nonpolyadenylated positive-sense RNA genome. We have recently identified sequences within the DEN 3' untranslated region (UTR) that modulate viral translation. Here, we show that the DEN type 2 (DEN2) 3'UTR s... | ["3' Untranslated Regions", "5' Untranslated Regions", 'Animals', 'Base Sequence', 'Cell Line', 'Cricetinae', 'Dengue Virus', 'Gene Expression Regulation, Viral', 'Molecular Sequence Data', 'Poly A', 'Protein Biosynthesis', 'RNA Caps', 'RNA, Messenger'] | 15,476,880 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['D13.444.735.544.875.885', 'D13.444.735.790.878.885', 'G05.360.340.024.220.880.885', 'G05.360.340.024.340.137.910.885'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Reinforcement Contingency Learning in Children with ADHD: Back to the Basics of Behavior Therapy. | Reinforcement deficits in ADHD may affect basic operant learning processes relevant for Behavioral Treatment. Behavior acquired under partial reinforcement extinguishes less readily after the discontinuation of reinforcement than behavior acquired under continuous reinforcement, a phenomenon known as the Partial Reinfo... | ['Attention Deficit Disorder with Hyperactivity', 'Behavior Therapy', 'Child', 'Conditioning, Operant', 'Extinction, Psychological', 'Female', 'Humans', 'Male', 'Reinforcement, Psychology'] | 31,292,806 | [['F03.625.094.150'], ['F04.754.137'], ['M01.060.406'], ['F02.463.425.179.509'], ['F02.463.425.770.232'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.770']] | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Constitutional MLH1 methylation presenting with colonic polyposis syndrome and not Lynch syndrome. | At least one-third of patients meeting clinical criteria for Lynch syndrome will have no germline mutation and constitutional epimutations leading to promoter methylation of MLH1 have been identified in a subset of these patients. We report the first case of constitutional MLH1 promoter methylation associated with a co... | ['Adenocarcinoma', 'Adult', 'Colonic Polyps', 'Colorectal Neoplasms', 'Colorectal Neoplasms, Hereditary Nonpolyposis', 'DNA Methylation', 'Female', 'Genetic Predisposition to Disease', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Immunohistochemistry', 'Male', 'Microsatellite Instability', 'Multiplex Polymerase ... | 26,781,822 | [['C04.557.470.200.025'], ['M01.060.116'], ['C23.300.825.411.235'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['C04.588.274.476.411.307.190', 'C04.700.250', 'C06.301.371.411.307.190', 'C06.405.249.411.307.190', 'C06.40... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Successful colonoscopic fecal transplant for severe acute Clostridium difficile pseudomembranous colitis. | Clostridium difficile-associated diarrhea has become one of the most common healthcare-associated infections, with significant morbidity and mortality, especially among the elderly in the inpatient setting. The standard approach with metronidazole and vancomycin is not very effective in treating patients with severe co... | ['Acute Disease', 'Aged', 'Colonoscopy', 'Enterocolitis, Pseudomembranous', 'Feces', 'Humans', 'Male', 'Remission Induction', 'Severity of Illness Index'] | 22,450,020 | [['C23.550.291.125'], ['M01.060.116.100'], ['E01.370.372.250.250.200', 'E01.370.388.250.250.250.160', 'E04.210.240.250.160', 'E04.502.250.250.250.160'], ['C01.150.252.410.222.310', 'C06.405.205.596.800', 'C06.405.469.363.800'], ['A12.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.860'], ['E05.318.308.980... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Subretinal Implantation of a Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium Monolayer in a Porcine Model. | The goal of this study was to quantitatively assess retinal thickness using spectral domain optical coherence tomography (SD-OCT) after subretinal implantation of human embryonic stem cell-derived retinal pigment epithelium in a porcine model. The implant is called CPCB-RPE1 for the California Project to Cure Blindness... | ['Animals', 'California', 'Human Embryonic Stem Cells', 'Humans', 'Retina', 'Retinal Pigment Epithelium', 'Swine', 'Tomography, Optical Coherence'] | 31,884,672 | [['B01.050'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['A11.872.700.250.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.729'], ['A09.371.670.500', 'A09.371.729.887'], ['B01.050.150.900.649.313.500.880'], ['E01.370.350.589.249.500', 'E01.370.350.825.805.500', 'E05.642.249.500']] | ['Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Morphological and genetic characterization of Echinococcus granulosus in the Slovak Republic. | The present study was undertaken to characterize more thoroughly aetiological agent of cystic echinococcosis that still represents a health problem in the Slovak Republic. Sequencing of the mitochondrial ND1 gene, Random Amplified Polymorphic DNA (RAPD) analysis and isoenzyme analyses were used to characterize genetica... | ['Animals', 'Base Sequence', 'Dogs', 'Echinococcosis', 'Echinococcus', 'Isoenzymes', 'Population', 'Slovakia'] | 12,606,100 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.649.313.750.250.216.200'], ['C01.610.335.190.396'], ['B01.050.500.500.736.215.327'], ['D08.811.348', 'D12.776.800.300'], ['N01.600'], ['Z01.542.248.797']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Gender and health social enterprises in Africa: a research agenda. | BACKGROUND: Health social enterprises in Africa working with community health workers (CHWs) are growing rapidly but understudied. In particular, gender equality issues related to their work has important public health and equity implications.METHODS: Particularly suited for generating timely findings from reviews at t... | ['Adult', 'Africa', 'Community Health Services', 'Community Health Workers', 'Female', 'Human Rights', 'Humans', 'Male', 'Middle Aged', 'Personnel Staffing and Scheduling', 'Sex Factors'] | 31,221,156 | [['M01.060.116'], ['Z01.058'], ['N02.421.143'], ['M01.526.485.067.080', 'N02.360.067.080'], ['I01.880.604.473', 'N03.706.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I03.946.225', 'N04.452.677.650'], ['N05.715.350.675', 'N06.850.490.875']] | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Evolution and characterization of a benzylguanine-binding RNA aptamer. | Repurposing the "protein-labeling toolkit" for RNA research could be a pragmatic approach for developing new RNA-labeling methods. We have evolved an RNA aptamer that tightly binds benzylguanine (bG), the key ligand for the protein SNAP-tag. The aptamer tightly binds bG fluorophores and can be purified from cellular RN... | ['Aptamers, Nucleotide', 'Base Sequence', 'Chromatography, Agarose', 'Guanidines', 'Molecular Structure', 'RNA', 'SELEX Aptamer Technique'] | 26,538,152 | [['D13.695.578.424.224'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.181.400.250.200'], ['D02.078.370'], ['G02.111.570', 'G02.466'], ['D13.444.735'], ['E05.197.312.500', 'J01.897.836.249.249.500']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Quantification of the Pharmacodynamic Interaction of Morphine and Gabapentin Using a Response Surface Approach. | The combination of morphine and gabapentin has shown to be promising for managing postoperative pain but finding the right dose for the combination has proven to be a challenge. The purpose of this study was to quantitatively characterize the pharmacodynamic interaction between the two drugs and to identify the optimal... | ['Amines', 'Analgesics', 'Animals', 'Cyclohexanecarboxylic Acids', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Gabapentin', 'Morphine', 'Pain, Postoperative', 'Rats', 'Rats, Sprague-Dawley', 'gamma-Aminobutyric Acid'] | 28,853,055 | [['D02.092'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['D02.241.223.268', 'D02.455.426.392.368.367.218'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['D02.092.521', 'D02.241.081.114.500.350.300', 'D02.241.223.268.469', 'D02.455.426.392.368.367.218.500', 'D12.125.190.350.225'],... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Computerized tomography of the otic capsule and otoliths in the oyster toadfish, Opsanus tau. | The neurocranium of the toadfish (Opsanus tau) exhibits a distinct translucent region in the otic capsule (OC) that may have functional significance for the auditory pathway. This study used ultrahigh resolution computerized tomography (100 µm voxels) to compare the relative density of three sites along the OC (dorsola... | ['Animals', 'Batrachoidiformes', 'Female', 'Imaging, Three-Dimensional', 'Male', 'Otolithic Membrane', 'Saccule and Utricle', 'Sex Characteristics', 'Skull', 'Tomography, X-Ray Computed'] | 25,502,869 | [['B01.050'], ['B01.050.150.900.493.039'], ['E01.370.350.400', 'L01.224.308.410'], ['A09.246.300.909.625.125.680'], ['A09.246.300.909.625'], ['G08.686.815'], ['A02.835.232.781'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Acute cyanosis following balloon angioplasty of residual arch obstruction after the Norwood I operation. | A 7-month-old child with residual aortic arch obstruction following a modified Norwood I operation developed profound cyanosis with subsequent bradycardia and hypotension immediately after successful balloon angioplasty. This complication of aortic angioplasty is specific to patients with this physiology. The pathophys... | ['Acute Disease', 'Angioplasty, Balloon', 'Aorta, Thoracic', 'Aortic Coarctation', 'Constriction, Pathologic', 'Cyanosis', 'Humans', 'Hypoplastic Left Heart Syndrome', 'Infant, Newborn', 'Male'] | 8,722,863 | [['C23.550.291.125'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['A07.015.114.056.372'], ['C14.240.400.090', 'C14.280.400.090', 'C16.131.240.400.090'], ['C23.300.287'], ['C23.888.248'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.240.400.625', 'C14.280.400.625'... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Tumor budding and poorly-differentiated cluster in prognostication in Stage II colon cancer. | Comparison between tumor budding (TB) and poorly-differentiated clusters (PDC) for prognostication in Stage II colon cancer was not extensively studied in literature. In this retrospective study, we assessed TB (according to the consensus statement in 2016) and PDC in 135 Stage II colon adenocarcinoma resection specime... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Colonic Neoplasms', 'Colorectal Neoplasms', 'Disease-Free Survival', 'Humans', 'Middle Aged', 'Neoplasm Grading', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Prognosis', 'Retrospective Studies'] | 29,487,008 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Newborn rabbit blood-brain barrier is selectively permeable and differs substantially from the adult. | Examination of blood-brain barrier (BBB) function by the intracarotid injection technique has been utilized in studies of newborn (6-30 h) and adult rabbits. The exclusion of mannitol (mol. wt. 182), dextran (mol. wt. 60,000-90,000), and indium-bound EDTA indicate that the newborn BBB has restrictive properties similar... | ['Adenine', 'Adenosine', 'Aging', 'Amino Acids', 'Animals', 'Animals, Newborn', 'Blood-Brain Barrier', 'Brain', 'Carbohydrate Metabolism', 'Cerebrovascular Circulation', 'Choline', 'Rabbits'] | 7,452,231 | [['D03.633.100.759.138'], ['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['G07.345.124'], ['D12.125'], ['B01.050'], ['B01.050.050.282'], ['A07.035', 'A08.186.211.035'], ['A08.186.211'], ['G02.111.158', 'G03.191'], ['G09.330.100.159'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.3... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Histone H3 lysine 36 methyltransferase Hypb/Setd2 is required for embryonic vascular remodeling. | HYPB is a human histone H3 lysine 36 (H3K36)-specific methyltransferase and acts as the ortholog of yeast Set2. This study explored the physiological function of mammalian HYPB using knockout mice. Homozygous disruption of Hypb impaired H3K36 trimethylation but not mono- or dimethylation, and resulted in embryonic leth... | ['Animals', 'Cells, Cultured', 'Embryo, Mammalian', 'Gene Expression Profiling', 'Gene Expression Regulation, Developmental', 'Histone-Lysine N-Methyltransferase', 'Humans', 'Methylation', 'Mice', 'Mice, Knockout', 'Neovascularization, Physiologic', 'RNA Interference'] | 20,133,625 | [['B01.050'], ['A11.251'], ['A16.254'], ['E05.393.332'], ['G05.308.310'], ['D08.811.913.555.500.800.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Short-term beta-adrenergic regulation of leptin, adiponectin and interleukin-6 secretion in vivo in lean and obese subjects. | AIM: Adipose tissue and skeletal muscle are endocrine organs, secreting substances that have been implicated in obesity-related disorders. This study examined short-term beta-adrenergic regulation of circulating leptin, adiponectin and interleukin-6 (IL-6) concentrations and secretion from abdominal subcutaneous adipos... | ['Adiponectin', 'Adrenergic beta-Agonists', 'Adult', 'Case-Control Studies', 'Forearm', 'Humans', 'Interleukin-6', 'Isoproterenol', 'Leptin', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Obesity', 'Statistics, Nonparametric', 'Stimulation, Chemical', 'Subcutaneous Fat, Abdominal'] | 18,435,774 | [['D06.472.699.042.249', 'D12.644.276.024.249', 'D12.644.548.011.249', 'D12.776.467.024.249', 'D23.529.024.249'], ['D27.505.519.625.050.100.200', 'D27.505.696.577.050.100.200'], ['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['A01.378.800.585'], ['B01.050.150.900.649.313... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mangiferin activates the Nrf2-ARE pathway and reduces etoposide-induced DNA damage in human umbilical cord mononuclear blood cells. | CONTEXT: Mangiferin (2-C-â-d-gluco-pyranosyl-1,3,6,7-tetrahydroxyxanthone) is a well-known natural antioxidant distributed in various plants of the Anacardiaceae and Gentianaceae families. Mangiferin can inhibit carcinogen-induced lung or colon tumor formation in experimental animals. However, the molecular mechanisms ... | ['Antineoplastic Agents, Phytogenic', 'Antioxidant Response Elements', 'Antioxidants', 'Comet Assay', 'DNA Damage', 'Electrophoretic Mobility Shift Assay', 'Etoposide', 'Female', 'Fetal Blood', 'Humans', 'Leukocytes, Mononuclear', 'Micronuclei, Chromosome-Defective', 'Micronucleus Tests', 'Microscopy, Confocal', 'NF-E2... | 25,380,307 | [['D27.505.954.248.179'], ['G02.111.570.080.689.675.700.040', 'G05.360.080.689.675.700.040', 'G05.360.340.024.340.137.750.680.765.040'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['E05.196.401.153.150', 'E05.301.300.100.150', 'E05.393.560.150', 'E05.940.560.150'], ['G05.200'], ['E05.196.401.500'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Beyond histone methyl-lysine binding: how malignant brain tumor (MBT) protein L3MBTL1 impacts chromatin structure. | Alterations in gene expression are commonly accompanied by changes in chromatin structure. Histone lysine residues of the so called "histone tails" are subject to various post-translational modifications among which methylation has been extensively studied over the past years. The presence and the extent of methylation... | ['Animals', 'Chromatin', 'Chromosomal Proteins, Non-Histone', 'Gene Expression Regulation, Neoplastic', 'Histones', 'Humans', 'Lysine', 'Methylation', 'Mitosis', 'Neoplasm Proteins', 'Protein Binding', 'Protein Structure, Tertiary', 'Repressor Proteins', 'Tumor Suppressor Proteins'] | 18,256,536 | [['B01.050'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D12.776.660.235', 'D12.776.664.235'], ['G05.308.370'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.49... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The shadow clinic: Emails, "curbsides," and "quick peeks" in pediatric dermatology. | BACKGROUND/OBJECTIVES: Curbside consultations are common in pediatric dermatology. There are both associated risks and benefits. Email, text messaging, and cell phone cameras have greatly facilitated this practice. We sought to characterize the nature of this practice among pediatric dermatologists and highlight concer... | ['Child', 'Dermatology', 'Electronic Mail', 'Humans', "Practice Patterns, Physicians'", 'Referral and Consultation', 'Surveys and Questionnaires', 'Telemedicine', 'Text Messaging'] | 31,177,554 | [['M01.060.406'], ['H02.403.225'], ['L01.178.847.249', 'L01.559.423.906.377.333'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.374.577', 'N05.300.625'], ['N04.452.758.849'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['H02.403.840', 'L01.178.847.652', 'N04.590.374.800'], ['L01.178... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Antinociceptive pharmacological profile of Dysphania graveolens in mouse. | This work evaluates the potential antinociceptive activity of Dysphania graveolens, traditional medicinal plant used in Mexico to treat stomach pain. A CH2Cl2-MeOH extract, infusion and essential oil from aerial parts of Dysphania graveolens were evaluated in hot plate and writhing tests in mice. The metabolites pinost... | ['Amaranthaceae', 'Analgesics', 'Animals', 'Male', 'Mice', 'Mice, Inbred ICR', 'Pain', 'Pain Measurement', 'Plant Extracts'] | 28,292,021 | [['B01.650.940.800.575.912.250.198.500.100'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.510', 'B01.050.150.900.649.313.992.635.505.500.400.510'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E01.370.600.550.324... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Normalized average glandular dose in molybdenum target-rhodium filter and rhodium target-rhodium filter mammography. | PURPOSE: To determine the normalized glandular dose (DgN) for molybdenum target-rhodium filter (Mo-Rh) and rhodium target-rhodium filter (Rh-Rh) mammography and compare the average glandular doses (Dg) that resulted with a conventional molybdenum target-molybdenum filter (Mo-Mo) source assembly.MATERIALS AND METHODS: X... | ['Adipose Tissue', 'Breast', 'Female', 'Humans', 'Mammography', 'Models, Structural', 'Molybdenum', 'Radiation Dosage', 'Radiation Protection', 'Rhodium', 'Skin', 'X-Ray Intensifying Screens'] | 8,090,926 | [['A10.165.114'], ['A01.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['J01.897.280.500.545', 'L01.178.820.090.545'], ['D01.268.556.555', 'D01.268.956.500', 'D01.552.544.555'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['N06.850.810.425'], ['D01.268.556.793', 'D01.268.956.781... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Role of the lipase-specific foldase of Burkholderia glumae as a steric chaperone. | Most lipases of Gram-negative bacteria require a lipase-specific foldase (Lif) in order to fold in the periplasm into their active, protease-resistant conformation prior to their secretion. The periplasmic domain of the Lif (amino acids 44-353) of Burkholderia glumae was purified as a His-tagged protein, and its functi... | ['Burkholderia', 'Circular Dichroism', 'Disulfides', 'Histidine', 'Kinetics', 'Lipase', 'Molecular Chaperones', 'Protein Folding'] | 10,859,310 | [['B03.660.075.090.688.100'], ['E05.196.867.151'], ['D01.248.497.158.874.390', 'D01.875.350.850.150', 'D02.886.520.150'], ['D12.125.072.329', 'D12.125.142.308'], ['G01.374.661', 'G02.111.490'], ['D08.811.277.352.100.400'], ['D12.776.580'], ['G01.154.651', 'G02.111.688']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of caffeine on the ATR/Chk1 pathway in the epidermis of UVB-irradiated mice. | Administration of caffeine was shown in earlier studies to enhance UVB-induced apoptosis and inhibit UVB-induced carcinogenesis in hairless SKH-1 mice. Here, we describe a potential mechanism for these in vivo effects. A single irradiation of mouse skin with UVB activated the ataxia-telangiectasia mutated- and Rad3-rel... | ['Animals', 'Apoptosis', 'Ataxia Telangiectasia Mutated Proteins', 'Caffeine', 'Cell Cycle Proteins', 'Checkpoint Kinase 1', 'Cyclin B', 'Cyclin B1', 'Female', 'Mice', 'Mice, Hairless', 'Mice, Knockout', 'Mitosis', 'Phosphorylation', 'Protein Kinases', 'Protein-Serine-Threonine Kinases', 'Skin', 'Skin Neoplasms', 'Tumo... | 18,381,462 | [['B01.050'], ['G04.146.954.035'], ['D08.811.913.696.620.682.700.097', 'D12.776.157.687.125', 'D12.776.660.720.125'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['D12.776.167'], ['D08.811.913.696.620.682.700.143'], ['D12.644.360.262.120', 'D12.776.167.218.120', 'D12.776.476.262.120'], ['D12.644.360.262.120.100... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Exercise in the heat is limited by a critical internal temperature. | We examined whether fatigue during exertional heat stress occurred at a critical internal temperature independent of the initial temperature at the start of exercise. Microwaves (2.1 GHz; 100 mW/cm(2)) were used to rapidly (3-8 min) heat rats before treadmill exercise to exhaustion. In a repeated-measures design, food-... | ['Animals', 'Body Temperature', 'Hot Temperature', 'Hypothalamus', 'Male', 'Microwaves', 'Physical Exertion', 'Rats', 'Rats, Sprague-Dawley', 'Running', 'Stereotaxic Techniques', 'Weight Loss'] | 10,926,668 | [['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['G11.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Helping patients and their family caregivers cope with cancer. | Family caregivers face multiple demands as they care for their loved ones with cancer, and these demands have increased dramatically in recent years. Patients with cancer now receive toxic treatments in outpatient settings and return home to the care of their family members. Some patients receive in-home infusions, whi... | ['Adaptation, Psychological', 'Caregivers', 'Communication', 'Emotions', 'Family Relations', 'Fear', 'Helping Behavior', 'House Calls', 'Humans', 'Neoplasms', "Nurse's Role", 'Nurse-Patient Relations', 'Oncology Nursing', 'Patient Education as Topic', 'Patients', 'Professional-Family Relations', 'Social Support', 'Spir... | 22,940,514 | [['F01.058'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['F01.145.209', 'L01.143'], ['F01.470'], ['F01.829.263.370', 'I01.880.853.150.439'], ['F01.470.361'], ['F01.145.813.225'], ['N04.452.758.307'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['F01.829.316.616.625.450', 'N05.300.100.337'], ['F01.829... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Absolute cardiovascular disease risk and shared decision making in primary care: a randomized controlled trial. | PURPOSE: We wanted to determine the effect of promoting the effective communication of absolute cardiovascular disease (CVD) risk and shared decision making through disseminating a simple decision aid for use in family practice consultations.METHODS: The study was based on a pragmatic, cluster randomized controlled tri... | ['Adult', 'Aged', 'Cardiovascular Diseases', 'Decision Making', 'Decision Support Techniques', 'Female', 'Health Behavior', 'Humans', 'Male', 'Middle Aged', 'Patient Education as Topic', 'Patient Participation', 'Patient Satisfaction', 'Physician-Patient Relations', 'Physicians, Family', 'Primary Health Care', 'Risk As... | 18,474,884 | [['M01.060.116'], ['M01.060.116.100'], ['C14'], ['F02.463.785.373'], ['E05.245', 'L01.313.500.750.190'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['I02.233.332.500', 'N02.421.726.407.680'], ['F01.100.150.750.500.620', 'F01.145.488.887.500.620', 'N02.421.143.212.300', 'N03.5... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Condition dependence of iridescent wing flash-marks in two species of dabbling ducks. | Growing empirical evidence supports the hypothesis of male mate choice for female ornaments which are thought to reflect individual quality and future breeding ability. While structural colors are clearly used in mate choice and pairing, the condition dependence of such traits is less obvious, particularly in females. ... | ['Analysis of Variance', 'Animals', 'Beak', 'Body Size', 'Color', 'Ducks', 'Feathers', 'Female', 'Linear Models', 'Male', 'Mating Preference, Animal', 'Pigmentation', 'Principal Component Analysis', 'Sex Characteristics', 'Species Specificity', 'Ultraviolet Rays', 'Visual Perception', 'Wings, Animal'] | 20,117,191 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['A13.114'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['G01.590.540.199'], ['B01.050.150.900.248.050.200', 'B01.050.150.900.248.690.345'], ['A13.370'], ['E05.318.740.500.500', 'E05.318.740.750.4... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
ATP-binding cassette transporter ABCA2 (ABC2) expression in the developing spinal cord and PNS during myelination. | We examined developmental characteristics of the ATP-binding cassette transporter ABCA2 (or ABC2) -expressing cells in rat spinal cord and peripheral nerves. In adult spinal cord, ABCA2 immunoreactivity was detected in lysosome-like organelles of mature oligodendrocyte cell bodies, and a single specific band was detect... | ['ATP-Binding Cassette Transporters', 'Age Factors', 'Animals', 'Animals, Newborn', 'Biomarkers', 'Cell Lineage', 'Ependyma', 'Glial Fibrillary Acidic Protein', 'Immunohistochemistry', 'Myelin Sheath', 'Oligodendroglia', 'Peripheral Nervous System', 'Rats', 'Rats, Sprague-Dawley', 'Schwann Cells', 'Spinal Cord'] | 12,210,128 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['B01.050.050.282'], ['D23.101'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['A08.186.211.140.460', 'A10.755.260'], ['D05.750.078.59... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Aryl hydrocarbon receptor mediates laminar fluid shear stress-induced CYP1A1 activation and cell cycle arrest in vascular endothelial cells. | AIMS: We investigated the mechanisms of shear stress (SS)-induced activation of cytochrome P450 (CYP) 1A1 and cell cycle arrest with regard to the role of the aryl hydrocarbon receptor (AhR), since AhR mediates the expression of CYP1A1 induced by polycyclic aromatic hydrocarbons (PAHs) and is thought to be involved in ... | ['Active Transport, Cell Nucleus', 'Basic Helix-Loop-Helix Transcription Factors', 'Benzoflavones', 'Cell Cycle', 'Cells, Cultured', 'Cyclin-Dependent Kinase Inhibitor p21', 'Cytochrome P-450 CYP1A1', 'Endothelial Cells', 'Enzyme Activation', 'Enzyme Induction', 'Humans', 'Mitogen-Activated Protein Kinases', 'Phosphory... | 18,065,768 | [['G03.143.310.100', 'G03.143.700.100'], ['D12.776.260.103', 'D12.776.930.125'], ['D03.383.663.283.266.450.175', 'D03.633.100.150.266.450.175'], ['G04.144'], ['A11.251'], ['D12.644.360.225.500', 'D12.776.157.687.250', 'D12.776.167.187.500', 'D12.776.476.225.500', 'D12.776.624.776.355.500', 'D12.776.660.720.250'], ['D08... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glucose intolerance develops prior to increased adiposity and accelerated cessation of estrous cyclicity in female growth-restricted rats. | BACKGROUND: The incidence of metabolic disease increases in early menopause. Low birth weight influences the age at menopause. Thus, this study tested the hypothesis that intrauterine growth restriction programs early reproductive aging and impaired glucose homeostasis in female rats.METHODS: Estrous cyclicity, body co... | ['Adiposity', 'Animals', 'Body Composition', 'Estrus', 'Female', 'Fetal Growth Retardation', 'Glucose', 'Glucose Intolerance', 'Glucose Tolerance Test', 'Homeostasis', 'Menopause', 'Organ Size', 'Rats', 'Testosterone', 'Time Factors', 'Uterus'] | 26,854,801 | [['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['B01.050'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['G08.686.195.500'], ['C13.703.277.370', 'C16.300.390', 'C23.550.393.450'], ['D09.947.875.359.448'], ['C18.452.394.952.500'], ['E01.370.225.124.100.355', 'E01.370.37... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Epithelialization of hydrogels achieved by amine functionalization and co-culture with stromal cells. | The aim of this study was to develop a hydrogel which would be suitable for corneal cell re-epithelialization when used as a corneal implant. To achieve this, a series of hydrogels were functionalized with primary amines by post-polymerization reactions between amine compounds and glycidyl ether groups attached to the ... | ['Amines', 'Animals', 'Cattle', 'Cell Communication', 'Cell Differentiation', 'Cells, Cultured', 'Coculture Techniques', 'Cornea', 'Epithelial Cells', 'Epithelium, Corneal', 'Humans', 'Hydrogels', 'Models, Biological', 'Stromal Cells'] | 17,888,510 | [['D02.092'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G04.085'], ['G04.152'], ['A11.251'], ['E05.481.500.374'], ['A09.371.060.217'], ['A11.436'], ['A09.371.060.217.325', 'A10.272.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.280.320.375', 'D26.255.165.320.375'], ['E05.599.395'], ['A11.32... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Developing a sustainable hip service in Cambodia. | OBJECTIVE: Initial report on establishment of a hip service in Phnom Penh, Cambodia at Children's Surgical Centre. We describe indications for total hip replacement (THR) and initial results.METHODS: A database was established to collect data and track patients for follow up. Initial data collected included; diagnosis,... | ['Adolescent', 'Adult', 'Aged', 'Arthroplasty, Replacement, Hip', 'Cambodia', 'Databases, Factual', 'Female', 'Femur Head Necrosis', 'Hip Injuries', 'Hip Prosthesis', 'Humans', 'Joint Diseases', 'Male', 'Middle Aged', 'Prosthesis Failure', 'Registries', 'Reoperation', 'Treatment Outcome', 'Young Adult'] | 25,044,267 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['Z01.252.145.182'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['C05.116.852.175', 'C23.550.717.732.368'], ['C26.531'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Effects of cocaine and quinpirole on perceptual and motor functions in baboons. | The effects of cocaine and quinpirole were studied in baboons to determine whether quinpirole, a relatively selective D2/D3 dopamine agonist, produced effects similar to those of cocaine on perceptual and motor processes. To measure perceptual and motor function, three baboons were trained to discriminate differences b... | ['Animals', 'Auditory Perception', 'Cocaine', 'Dopamine Agonists', 'Dopamine Uptake Inhibitors', 'Dose-Response Relationship, Drug', 'Male', 'Papio', 'Perception', 'Psychomotor Performance', 'Quinpirole', 'Reaction Time', 'Verbal Behavior'] | 9,399,365 | [['B01.050'], ['F02.463.593.071', 'G07.888.125'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['D27.505.519.625.150.151', 'D27.505.696.577.150.151'], ['D27.505.519.562.437.220', 'D27.505.519.625.150.800', 'D27.505.519.625.600.220', 'D27.505.696.577.150.800', 'D27.505.696.57... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A randomized control clinical trial of Euruikang (docetaxel) in treatment of advanced non-small cell lung cancer (NSCLC)]. | BACKGROUND & OBJECTIVE: Docetaxel is one of the major drugs for advanced non-small cell lung cancer (NSCLC) treatment in clinical use. It is reported that the response rate of docetaxel alone is about 20% and its major toxicity is myelosuppression. The study was to evaluate the efficacy and tolerability of docetaxel (m... | ['Adolescent', 'Adult', 'Aged', 'Alopecia', 'Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma, Non-Small-Cell Lung', 'Cisplatin', 'Docetaxel', 'Female', 'Humans', 'Infusions, Intravenous', 'Leukopenia', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Nausea', 'Neoplasm Staging', 'Remission Induction', 'Taxoids', '... | 16,965,682 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C17.800.329.937.122', 'C23.300.035'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D02.455.426.392.368.242.888.3... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Wilson disease: findings at MR imaging and CT of the brain with clinical correlation. | PURPOSE: To describe the spectrum of brain abnormalities in Wilson disease (hepatolenticular degeneration) as depicted at magnetic resonance (MR) imaging and computed tomography (CT) and to relate these findings to neurologic and hepatologic abnormalities.MATERIALS AND METHODS: Fifty patients with Wilson disease partic... | ['Adult', 'Brain', 'Cross-Sectional Studies', 'Female', 'Hepatolenticular Degeneration', 'Humans', 'Hypertension, Portal', 'Liver', 'Liver Circulation', 'Magnetic Resonance Imaging', 'Male', 'Neurologic Examination', 'Portal System', 'Tomography, X-Ray Computed', 'Ultrasonography'] | 8,596,862 | [['M01.060.116'], ['A08.186.211'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C06.552.413', 'C10.228.140.079.493', 'C10.228.140.163.100.360', 'C10.228.662.400', 'C10.574.500.487', 'C16.320.400.361', 'C16.320.565.189.360', 'C16.320.565.618.403', 'C18.452.132.100.360', 'C18.452.648.1... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Roentgen findings in bronchial tuberculosis]. | To determine the value of chest roentgenographic findings in the diagnosis and therapy of endobronchial tuberculosis we analysed roentgenograms of 41 patients with endoscopically confirmed tuberculous involvement of the intrathoracic airways. 40 patients had infiltrates typical for pulmonary tuberculosis predominantly ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bronchial Diseases', 'Bronchoscopy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Radiography', 'Retrospective Studies', 'Tracheal Diseases', 'Tuberculosis', 'Tuberculosis, Pulmonary'] | 7,824,499 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C08.127'], ['E01.370.386.105', 'E01.370.388.250.100', 'E04.502.250.100', 'E04.928.600.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.350.700'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Deficiency of Adenosine Deaminase 2 Causes Antibody Deficiency. | PURPOSE: Determining the monogenic cause of antibody deficiency and immune dysregulation in a non-consanguineous family with healthy parents, two affected children, and one unaffected child.METHODS: Whole Exome Sequencing (WES) was performed in the index family. WES results were confirmed by Sanger Sequencing. Dried pl... | ['Adenosine Deaminase', 'Adolescent', 'Adult', 'Child', 'Common Variable Immunodeficiency', 'Dried Blood Spot Testing', 'Exome', 'Female', 'Gene Expression', 'Heterozygote', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Immunoglobulin A', 'Immunoglobulin G', 'Intercellular Signaling Peptides and Proteins', 'Lupus... | 26,922,074 | [['D08.811.277.151.486.075'], ['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['C20.673.330'], ['E01.370.225.124.100.232', 'E05.200.124.100.232'], ['G05.360.340.011'], ['G05.297'], ['G05.380.383'], ['E05.393.760.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Diabetic photographic eye screening using a mobile unit in Tayside, Scotland. | Early detection and hospital referral of patients with diabetic changes (retinopathy) is essential if laser photocoagulation is to be effective. The British Diabetic Association (BDA) have therefore funded several diabetic mobile eye screening units and donated them to areas throughout the country, the aim being to scr... | ['Diabetic Retinopathy', 'Fundus Oculi', 'Humans', 'Mass Screening', 'Mobile Health Units', 'Photography', 'Scotland'] | 1,460,238 | [['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['A09.371.729.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.780.500'], ['N02.278.421.702', 'N02.421.726.233.628']... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Transtrochanteric rotational osteotomy for late-onset Legg-Calve-Perthes disease. | BACKGROUND: The pathology of late-onset Legg-Calve-Perthes disease (LCPD) is similar to that of avascular necrosis of the femoral head in adult and is associated with poorer prognosis of the hip. The optimal treatment for this condition is still controversial. The purpose of this study was to evaluate the long-term cli... | ['Adolescent', 'Age of Onset', 'Child', 'Female', 'Femur Head', 'Femur Head Necrosis', 'Follow-Up Studies', 'Humans', 'Legg-Calve-Perthes Disease', 'Male', 'Osteotomy', 'Retrospective Studies', 'Severity of Illness Index', 'Time Factors', 'Treatment Outcome'] | 21,857,443 | [['M01.060.057'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.406'], ['A02.835.232.043.150.343'], ['C05.116.852.175', 'C23.550.717.732.368'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.852.175.570'],... | ['Named Groups [M]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Outcome after procedures for retained blood syndrome in coronary surgery. | OBJECTIVES: Incomplete drainage of blood from around the heart and lungs can lead to retained blood syndrome (RBS) after cardiac surgery. The aim of this study was to assess the incidence of and the outcome after procedures for RBS in patients undergoing isolated coronary artery bypass grafting (CABG).METHODS: A total ... | ['Aged', 'Blood Loss, Surgical', 'Coronary Artery Bypass', 'Female', 'Fibrinolytic Agents', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Retrospective Studies', 'Thoracentesis', 'Treatment Outcome'] | 28,329,287 | [['M01.060.116.100'], ['C23.550.414.300', 'C23.550.505.300'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['D27.505.519.421.750', 'D27.505.954.411.320', 'D27.505.954.502.427'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E05.318.37... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Normal cortical bone mass in patients after long term coumadin therapy. | Clinical delineation of the warfarin embryopathy and the recent discovery of osteocalcin (a vitamin K-dependent bone protein) suggest that coumadin therapy could adversely affect the skeleton. Using bone densitometry and metacarpal cortical width measurement, we found normal cortical bone mass in 17 adults receiving lo... | ['Adult', 'Aged', 'Bone and Bones', 'Densitometry', 'Female', 'Humans', 'Male', 'Metacarpus', 'Middle Aged', 'Vitamin K', 'Warfarin'] | 7,054,229 | [['M01.060.116'], ['M01.060.116.100'], ['A02.835.232', 'A10.165.265'], ['E05.196.712.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.800.667.572'], ['M01.060.116.630'], ['D02.455.426.559.847.638.721.374', 'D02.455.849.291.523.500', 'D04.615.638.721.374'], ['D03.383.663.283.446.520.914', 'D03.633.100.1... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
IL4 limits the efficacy of tumor-targeted antibody therapy in a murine model. | Tumor-targeted antibody therapy has had a major impact on reducing morbidity and mortality in a wide range of cancers. Antibodies mediate their antitumor activity in part by activating immune effector cells; however, the tumor microenvironment (TME) is enriched with cellular and soluble mediators that actively suppress... | ['Animals', 'Antibodies, Monoclonal', 'Antibodies, Monoclonal, Humanized', 'Antineoplastic Combined Chemotherapy Protocols', 'Blotting, Western', 'Enzyme-Linked Immunosorbent Assay', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Immunotherapy', 'Interleukin-4', 'Mice', 'Mice, Transgenic', 'Real-Time Polymerase C... | 25,204,776 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E05.196.401.143', 'E05.301.300.096', 'E05.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The 75th anniversary of Military Sanatorium "Volga"]. | The article presents the history of development and becoming of a military sanatorium Volga. In the article was shown the structure of sanatorium and units of rehabilitation treatment, was shortly observed an individual program of rehabilitation of military servicemen. There were marked veterans of sanatorium, who have... | ['Health Resorts', 'History, 20th Century', 'History, 21st Century', 'Military Medicine', 'Rehabilitation Centers', 'Russia', 'Workforce'] | 20,020,619 | [['N02.278.330'], ['K01.400.504.968'], ['K01.400.504.984'], ['H02.403.500'], ['N02.278.808'], ['Z01.252.122.500', 'Z01.542.248.775'], ['N04.452.525']] | ['Health Care [N]', 'Humanities [K]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Obstetricians and the 2009-2010 H1N1 vaccination effort: implications for future pandemics. | Our objective was to describe the experiences of obstetricians during the 2009-2010 H1N1 vaccination campaign in order to identify possible improvements for future pandemic situations. We conducted a cross-sectional mail survey of a national random sample of 4,000 obstetricians, fielded in Summer 2010. Survey items inc... | ['Adult', 'Attitude of Health Personnel', 'Cross-Sectional Studies', 'Female', 'Health Care Surveys', 'Health Promotion', 'Humans', 'Influenza A Virus, H1N1 Subtype', 'Influenza Vaccines', 'Influenza, Human', 'Male', 'Mass Vaccination', 'Middle Aged', 'Obstetrics', 'Pandemics', "Physician's Role", "Practice Patterns, P... | 22,911,451 | [['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Phenomena and P... | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Striving for liminality: Eating disorders and social suffering. | In this article, I argue that eating disorders constitute a form of social suffering, in which sufferers embody liminality as a response to, and a reflection of, oppressive sociality, structural violence, and institutional constraints. Based on the illness narratives of people with anorexia nervosa, bulimia nervosa, an... | ['Adolescent', 'Adult', 'Feeding and Eating Disorders', 'Female', 'Humans', 'Israel', 'Male', 'Personal Narratives as Topic', 'Social Behavior', 'Stress, Psychological', 'Young Adult'] | 29,757,091 | [['M01.060.057'], ['M01.060.116'], ['F03.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.375'], ['K01.517.211.753'], ['F01.145.813'], ['F01.145.126.990', 'F02.830.900'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
HNF1á | This study is aimed at evaluating the effects, functions, and mechanism of HNF1á on hepatic glycolipid metabolism. In this study, free fatty acid- (FFA-) induced steatosis of hepatocyte liver cell LO2 was used as an in vitro model. The methods of Oil Red O staining, RT-qPCR, western blot, and immunofluorescence stainin... | ['Animals', 'Gene Expression Regulation', 'Glycolipids', 'Hepatocyte Nuclear Factor 1-alpha', 'Hepatocytes', 'Humans', 'Insulin', 'Insulin Resistance', 'Lipid Metabolism', 'Lipids', 'Liver', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Organ Size', 'Phosphorylation', 'STAT3 Transcription Factor', 'Signal Transduction', 'Supp... | 31,223,625 | [['B01.050'], ['G05.308'], ['D09.400.410', 'D10.390'], ['D12.776.260.262.500.500', 'D12.776.260.400.218.500', 'D12.776.660.352.500.500', 'D12.776.930.318.500.500'], ['A11.436.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['C18.452.394.968.500', '... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Attentional control underlies the perceptual load effect: Evidence from voxel-wise degree centrality and resting-state functional connectivity. | The fact that interference from peripheral distracting information can be reduced in high perceptual load tasks has been widely demonstrated in previous research. The modulation from the perceptual load is known as perceptual load effect (PLE). Previous functional magnetic resonance imaging (fMRI) studies on perceptual... | ['Adolescent', 'Adult', 'Attention', 'Brain', 'Brain Mapping', 'Executive Function', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Neural Pathways', 'Neuropsychological Tests', 'Perception', 'Reaction Time', 'Rest', 'Young Adult'] | 28,888,953 | [['M01.060.057'], ['M01.060.116'], ['F02.830.104.214'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.217'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A08.612'], ['F04.711.513'], ['F02.463.593'], ['E05.796.817', 'F02.830.650', 'F0... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
A method for measuring colocalization of presynaptic markers with anatomically labeled axons using double label immunofluorescence and confocal microscopy. | Information concerning the location and distribution of presynaptic neurotransmitter release sites within anatomically labeled axons would be of value for a large number of studies in functional anatomy, development, and plasticity. Here we report a method for localizing presynaptic sites within identified arbors of in... | ['Animals', 'Artifacts', 'Axons', 'Biomarkers', 'Cats', 'Differential Threshold', 'Fluorescent Antibody Technique', 'Microscopy, Confocal', 'Neurotransmitter Agents', 'Phytohemagglutinins', 'Presynaptic Terminals', 'Synaptophysin', 'Tissue Distribution'] | 10,661,840 | [['B01.050'], ['E05.047'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['D23.101'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['F02.463.593.710.370'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.37... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of commercial assays and laboratory developed tests for detection of SARS-CoV-2. | The global COVID-19 pandemic has led to the rapid development of tests for detection of SARS-CoV-2. Studies are required to assess the relative performance of different assays. Here, we compared the performance of two commercial assays, the cobas® SARS-CoV-2 (Roche Diagnostics) and Xpert® Xpress SARS-CoV-2 (Cepheid®) t... | ['Betacoronavirus', 'COVID-19', 'COVID-19 Testing', 'COVID-19 Vaccines', 'Clinical Laboratory Techniques', 'Coronavirus Infections', 'Humans', 'Molecular Diagnostic Techniques', 'Pandemics', 'Pneumonia, Viral', 'Reagent Kits, Diagnostic', 'SARS-CoV-2', 'Sensitivity and Specificity'] | 32,920,028 | [['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['E01.370.225.312', 'E05.200.312'], ['D20.215.894.899.085'], ['E01.370.225', 'E05.200'], ['C01.925.782.600.550.200'], ['B01.050.150.900... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The Association of Polyunsaturated Fatty Acid ä-5-Desaturase Activity with Risk Factors for Type 2 Diabetes Is Dependent on Plasma ApoB-Lipoproteins in Overweight and Obese Adults. | Background: ä-5 and ä-6 desaturases (D5D and D6D) catalyze the endogenous conversion of n-3 (ù-3) and n-6 (ù-6) polyunsaturated fatty acids (PUFAs). Their activities are negatively and positively associated with type 2 diabetes (T2D), respectively, by unclear mechanisms. Elevated plasma apoB-lipoproteins (measured as p... | ['Apolipoproteins B', 'Diabetes Mellitus, Type 2', 'Fatty Acid Desaturases', 'Female', 'Gene Expression Regulation, Enzymologic', 'Humans', 'Male', 'Middle Aged', 'Overweight', 'Risk Factors'] | 30,535,058 | [['D10.532.091.300', 'D12.776.070.400.300', 'D12.776.521.120.300'], ['C18.452.394.750.149', 'C19.246.300'], ['D08.811.682.690.708.392'], ['G05.308.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.888.144.699', 'E01.370.600.115.100.160.120.699', 'G07.100.100.160.120.699'], ['E05.318.740... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enzymic synthesis of N-acetyl-L-phenylalanine in Escherichia coli K12. | 1. Cell-free extracts of Escherichia coli K12 catalyse the synthesis of N-acetyl-l-phenylalanine from acetyl-CoA and l-phenylalanine. 2. The acetyl-CoA-l-phenylalanine alpha-N-acetyltransferase was purified 160-fold from cell-free extracts. 3. The enzyme has a pH optimum of 8 and catalyses the acetylation of l-phenylal... | ['Acetates', 'Acyltransferases', 'Alanine', 'Ammonium Sulfate', 'Calcium Phosphates', 'Carbon Isotopes', 'Cell-Free System', 'Chromatography, Gel', 'Coenzyme A', 'Escherichia coli', 'Histidine', 'Hydrogen-Ion Concentration', 'Phenylalanine', 'Sulfhydryl Reagents', 'Ultracentrifugation'] | 4,943,352 | [['D02.241.081.018', 'D10.251.400.045'], ['D08.811.913.050'], ['D12.125.042'], ['D01.625.062.374', 'D01.875.800.800.850.050'], ['D01.029.260.700.675.374.075', 'D01.146.360', 'D01.695.625.675.650.075'], ['D01.268.150.075', 'D01.496.123'], ['A11.284.835.168'], ['E05.196.181.400.250'], ['D03.633.100.759.646.138.382', 'D08... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Elevated incidence of lung cancer among HIV-infected individuals. | PURPOSE: People with HIV infection in the United States frequently smoke tobacco. We sought to characterize lung cancer incidence among HIV-infected individuals, examine whether cancer risk was related to HIV-induced immunosuppression, and assess whether the high prevalence of smoking explained elevated risk.METHODS: W... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'HIV Infections', 'Humans', 'Immunocompromised Host', 'Incidence', 'Longitudinal Studies', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Risk Factors', 'Smoking'] | 16,549,832 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.470'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
JCAHO strengthening its infection standards. | CDC guideline shows hand washing is one of the main ways to stop cross-infection. Statistics show 90,000 health care-associated infection-related deaths per year. Pressure has been increased on top-level management in health care organizations. | ['Accreditation', 'Centers for Disease Control and Prevention, U.S.', 'Cross Infection', 'Guidelines as Topic', 'Hand Disinfection', 'Humans', 'Infection Control', 'Joint Commission on Accreditation of Healthcare Organizations', 'Leadership', 'Safety Management', 'United States'] | 14,870,523 | [['N03.706.110.070', 'N05.700.200.100'], ['I01.409.418.750.600.650.200', 'N03.540.348.500.500.600.650.225'], ['C01.248', 'C23.550.291.875.500'], ['N04.761.700.350', 'N05.700.350'], ['N06.850.670.150.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.780.200.450'], ['N03.706.110.070.410', 'N05.700.200.100... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Percutaneous fibrin sheath stripping versus transcatheter urokinase infusion for malfunctioning well-positioned tunneled central venous dialysis catheters: a prospective, randomized trial. | PURPOSE: To compare central dialysis catheter patency rates after stripping procedures with those after urokinase (UK) infusion.MATERIALS AND METHODS: Fifty-seven tunneled catheters with either (i) flow rates less than 250 mL/min and established baseline flow rates > or = 300 mL/min or (ii) flow rates 50 mL/min less th... | ['Adult', 'Aged', 'Aged, 80 and over', 'Catheterization, Central Venous', 'Catheters, Indwelling', 'Chi-Square Distribution', 'Equipment Failure', 'Female', 'Fibrin', 'Humans', 'Male', 'Middle Aged', 'Plasminogen Activators', 'Prospective Studies', 'Radiography, Interventional', 'Renal Dialysis', 'Statistics, Nonparame... | 11,041,467 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['E07.132.500'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E05.325'], ['D12.776.124.270'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Protein encapsulation in and release from monodisperse double-wall polymer microspheres. | Biodegradable polymer double-wall microspheres (DWMS) are promising vehicles for macromolecular therapeutics such as proteins and peptides. Using precision particle fabrication (PPF) technology, uniform DWMS with outer diameter approximately 55 ìm were fabricated comprising poly(lactide-co-glycolide) cores encapsulatin... | ['Animals', 'Cattle', 'Delayed-Action Preparations', 'Lactic Acid', 'Microspheres', 'Particle Size', 'Polyesters', 'Polymers', 'Serum Albumin, Bovine'] | 23,529,836 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['D26.255.210', 'E02.319.300.253'], ['D02.241.511.459.450'], ['E07.565'], ['G02.712'], ['D05.750.728', 'D25.720.728', 'J01.637.051.720.728'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['D12.776.034.841.540', 'D12.776.124.727.875']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Muscle carnitine deficiency and lipid storage myopathy in patients with mitochondrial myopathy. | Abnormal carnitine distribution in muscle was found in 22 of 77 patients (29%), with mitochondrial myopathy. Furthermore, total (TC) and free (FC) carnitine levels in muscle were lower in patients than in controls (P < 0.01). Muscle long-chain acylcarnitines (LCAC) were significantly increased in these patients (P < 0.... | ['Adolescent', 'Adult', 'Carnitine', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Mitochondrial Myopathies', 'Muscles'] | 8,505,934 | [['M01.060.057'], ['M01.060.116'], ['D02.092.877.883.099'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['C05.651.460', 'C10.668.491.500', 'C18.452.660.560'], ['A02.633', 'A10.690']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Functional effects of amino acid substitutions within the large binding pocket of the phosphotriesterase OpdA from Agrobacterium sp. P230. | The phosphotriesterase OpdA from Agrobacterium sp. P230 has about 10-fold higher activity for dimethyl organophosphate (OP) insecticides, than its homologue from Flavobacterium sp. ATCC27551, organophosphate hydrolase (OPH). OpdA shows about 10% amino acid sequence divergence from OPH and also has a 20 residue C-termin... | ['Amino Acid Sequence', 'Amino Acid Substitution', 'Base Sequence', 'Catalytic Domain', 'DNA, Bacterial', 'Isoflurophate', 'Methyl Parathion', 'Models, Molecular', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Parathion', 'Phosphoric Monoester Hydrolases', 'Recombinant Fusion Proteins', 'Rhizobium', 'Sequen... | 16,734,778 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D13.444.308.212'], ['D02.705.429.750.249'], ['D02.705.400.625.600.500', 'D02.705.539.345.600.500', 'D02.886.300.69... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Surgical "Fat Patch" Improves Secondary Intracranial Hypotension Orthostatic Headache Associated with Lumbosacral Dural Ectasia. | BACKGROUND: Secondary intracranial hypotension is a clinical syndrome associated with reduction of cerebrospinal fluid volume and dural continuity violation. The main symptoms are orthostatic headache associated with nausea, vomiting, diplopia, dizziness, and tinnitus. The treatment is usually nonspecific.CASE DESCRIPT... | ['Adult', 'Blood Patch, Epidural', 'Cerebrospinal Fluid Leak', 'Dilatation, Pathologic', 'Dura Mater', 'Female', 'Headache', 'Humans', 'Intracranial Hypotension', 'Lumbosacral Region'] | 28,866,058 | [['M01.060.116'], ['E02.095.125', 'E02.319.267.530.580.300.145'], ['C10.597.114', 'C10.900.300.109', 'C23.888.592.114', 'C26.915.300.225'], ['C23.300.325'], ['A08.186.566.395'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.638'], ['A01.923.176.519']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Indomethacin for preterm labor: fetal toxicity in a dizygotic twin gestation. | Indomethacin was given for the treatment of preterm labor in a twin pregnancy at a dosage of 200 mg/day for 7 days beginning at 34 weeks and 5 days' gestation. During treatment, one twin developed closure of the ductus arteriosus, tricuspid regurgitation, right ventricular dysfunction, and pericardial effusion. Severe ... | ['Abnormalities, Drug-Induced', 'Adult', 'Diseases in Twins', 'Drug Monitoring', 'Ductus Arteriosus', 'Female', 'Fetal Diseases', 'Humans', 'Indomethacin', 'Obstetric Labor, Premature', 'Oligohydramnios', 'Pericardial Effusion', 'Pregnancy', 'Tricuspid Valve Insufficiency', 'Ultrasonography'] | 1,923,225 | [['C16.131.042'], ['M01.060.116'], ['C23.550.291.750'], ['E01.370.520.200'], ['A07.541.278.395', 'A16.378.303.395'], ['C13.703.277', 'C16.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.420'], ['C13.703.420.491'], ['C13.703.560'], ['C14.280.695'], ['G08.686.784.769'], ['C14.280.484.856'], ['E0... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Electrostimulation of the interatrial septum]. | The first clinical experience of the successful application of electrostimulation of the atrial septum is described. Sickle-shaped electrodes were used for this purpose. Electrostimulation of the atrial septum was medically indicated in all cases. In 2 cases the electrode was fixed to the atrial septum after open-heart... | ['Cardiac Pacing, Artificial', 'Electrodes', 'Heart Septum', 'Humans', 'Male', 'Middle Aged', 'Pacemaker, Artificial', 'Sick Sinus Syndrome', 'Tachycardia, Paroxysmal'] | 6,521,217 | [['E02.331.200'], ['E07.305.250'], ['A07.541.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E07.305.250.750'], ['C14.280.067.093.249', 'C14.280.067.558.536', 'C14.280.123.500.536', 'C23.550.073.093.249', 'C23.550.073.425.440'], ['C14.280.067.845.695', 'C14.280.123.875.695', 'C23.550.073.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Regulation of interstitial excitatory amino acid concentrations after cortical contusion injury. | Increases in brain interstitial excitatory amino acid (EAA(I)) concentrations after ischemia are ameliorated by use-dependent Na+ channel antagonists and by supplementing interstitial glucose, but the regulation of EAA(I) after traumatic brain injury (TBI) is unknown. We studied the regulation of EAA(I) after TBI using... | ['Animals', 'Aspartic Acid', 'Brain Injuries', 'Cerebral Cortex', 'Disease Models, Animal', 'Excitatory Amino Acids', 'Extracellular Space', 'Glucose', 'Glutamic Acid', 'Glycine', 'Hippocampus', 'Male', 'Microdialysis', 'Neurons', 'Rats', 'Rats, Sprague-Dawley', 'Sodium Channels', 'Up-Regulation'] | 12,062,471 | [['B01.050'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['A08.186.211.200.885.287.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.125.427'], ['A10.082.500', 'A11.284.295'], ['D09.947.875.359.448'], ['D12.125.067.625.349', 'D12.125.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Council ofMedical Specialty Societies: committed to continuing medical education reform. | The Council of Medical Specialty Societies (CMSS) recognizes the need for continuing medical education (CME) reform and intends to be actively engaged in that process. While recognizing that CME reform must involve many organizations, the CMSS and particularly the 23 societies that make up the CMSS are in a position to... | ['Education, Medical, Continuing', 'Humans', 'Medicine', 'Organizational Innovation', 'Societies', 'Specialization', 'United States'] | 16,173,050 | [['I02.358.212.350', 'I02.358.399.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403'], ['N04.452.610'], ['N03.540.828'], ['H02.811'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Health-Related Quality of Life With Ulipristal Acetate for Treatment of Uterine Leiomyomas: A Randomized Controlled Trial. | OBJECTIVE: To investigate effects of ulipristal acetate on health-related quality of life (QOL) and symptom severity in women with symptomatic uterine leiomyomas and abnormal uterine bleeding.METHODS: Women were randomized to ulipristal (5 mg, 10 mg) or placebo in two phase 3, multicenter, double-blind, placebo-control... | ['Administration, Oral', 'Adult', 'Antineoplastic Agents, Hormonal', 'Double-Blind Method', 'Female', 'Humans', 'Leiomyoma', 'Norpregnadienes', 'Quality of Life', 'Surveys and Questionnaires', 'Treatment Outcome', 'Uterine Neoplasms'] | 30,969,201 | [['E02.319.267.100'], ['M01.060.116'], ['D27.505.954.248.169'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.590.450'], ['D04.210.500.668.651.443'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E05.31... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Carbon frames. Positioning and reduction aids in tibial intramedullary nailing with unreamed technique]. | Intramedullary stabilisation of long bones is an established treatment option since K?ntscher. Especially for tibial nailing different methods were proposed in the past, were as the use of a fracture table was more or less the standard procedure. Since 4 years now we are nailing tibial fractures without fracture table.... | ['Adult', 'Aged', 'Ankle Injuries', 'Carbon', 'External Fixators', 'Female', 'Fracture Fixation, Intramedullary', 'Humans', 'Knee Injuries', 'Male', 'Middle Aged', 'Surgical Instruments', 'Tibial Fractures'] | 10,763,365 | [['M01.060.116'], ['M01.060.116.100'], ['C26.558.100'], ['D01.268.150'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['E04.555.300.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558.554'], ['M01.060.116.630'], ['E07.858.700'], ['C26.404.875', 'C26.558.857']] | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Determination of cell proliferation using Mcm2 antigen and evaluation of apoptosis and TGF-beta1 expression in GH-secreting or clinically nonfunctioning pituitary adenomas. | Pituitary adenomas (PA) occasionally show aggressive behavior, with invasion of the surrounding tissues. The identification of markers able to recognize aggressive PA in early stages remains a challenge. We aimed to determine the expression of a new cell proliferation marker, Mcm2, and the presence of apoptosis in PA, ... | ['Adult', 'Apoptosis', 'Cell Cycle Proteins', 'Cell Growth Processes', 'Female', 'Human Growth Hormone', 'Humans', 'Immunohistochemistry', 'In Situ Nick-End Labeling', 'Ki-67 Antigen', 'Male', 'Middle Aged', 'Minichromosome Maintenance Complex Component 2', 'Nuclear Proteins', 'Pituitary Neoplasms', 'Statistics, Nonpar... | 20,174,894 | [['M01.060.116'], ['G04.146.954.035'], ['D12.776.167'], ['G04.161', 'G07.345.249.410'], ['D06.472.699.631.525.425.875', 'D12.644.548.691.525.425.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Dendritic cells treated with lipopolysaccharide up-regulate serine protease inhibitor 6 and remain sensitive to killing by cytotoxic T lymphocytes in vivo. | Ag presentation by dendritic cells (DC) in vivo is essential to the initiation of primary and secondary T cell responses. We have reported that DC presenting Ag in the context of MHC I molecules also become targets of specific CTL and are rapidly killed in mice. However, activated DC up-regulate expression of serine pr... | ['Animals', 'Cell Death', 'Cells, Cultured', 'Cytotoxicity, Immunologic', 'Dendritic Cells', 'Immunity, Innate', 'Lipopolysaccharides', 'Lymphocyte Activation', 'Membrane Proteins', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'NIH 3T3 Cells', 'Serine Endopeptidases', 'Serpins', 'T-Lymphocytes, Cytotoxic', 'Up-Reg... | 19,050,252 | [['B01.050'], ['G04.146'], ['A11.251'], ['G12.287'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['G12.450.564'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Epstein-Barr virus (EBV) associated lymphoepithelioma-like thymic carcinoma associated with paraneoplastic syndrome of polymyositis: a rare tumor with rare association. | Thymic carcinomas are rare neoplasms representing less than 1% of all thymic malignancies arising from thymic epithelium. Lymphoepithelioma-like thymic carcinoma is a high grade neoplasm with aggressive features and frequent metastasis. Association of lymphoepithelioma-like thymic carcinomas with Epstein-Barr virus was... | ['Adult', 'Carcinoma', 'Herpesvirus 4, Human', 'Humans', 'Male', 'Neoplasm Metastasis', 'Paraneoplastic Syndromes', 'Polymyositis', 'Radiography, Thoracic', 'Thymus Neoplasms', 'Tomography, X-Ray Computed'] | 19,893,401 | [['M01.060.116'], ['C04.557.470.200'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650', 'C23.550.727.650'], ['C04.730'], ['C05.651.594.819', 'C10.668.491.562.575'], ['E01.370.350.700.730'], ['C04.588.894.949', 'C15.604.86... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Crystal structure of 2-selenobenzyl-1-benzoic acid. | C14H12O2Se is monoclinic, P2(1)/c. Unit-cell dimensions at 293 K are a = 8.1055(7), b = 5.8403(11), c = 26.0302(17)A, beta = 94.560(5) degrees, V = 1228.3(3)A3, Dx = 1.575 g/cm3, and Z = 4. The R value is 0.048 for 2144 observed reflections. The dihedral angle between the phenyl rings is 74.9(2)degrees. There is an int... | ['Benzoates', 'Crystallography, X-Ray', 'Free Radical Scavengers', 'Hydrogen Bonding', 'Molecular Structure', 'Selenium Compounds'] | 14,516,097 | [['D02.241.223.100', 'D02.455.426.559.389.127'], ['E05.196.309.742.225'], ['D27.505.519.217.500'], ['G02.282'], ['G02.111.570', 'G02.466'], ['D01.810']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bax dimerizes via a symmetric BH3:groove interface during apoptosis. | During apoptotic cell death, Bax and Bak change conformation and homo-oligomerize to permeabilize mitochondria. We recently reported that Bak homodimerizes via an interaction between the BH3 domain and hydrophobic surface groove, that this BH3:groove interaction is symmetric, and that symmetric dimers can be linked via... | ['Animals', 'Apoptosis', 'Cell Line, Transformed', 'Cytochromes c', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Mice', 'Mice, Knockout', 'Mitochondria', 'Protein Multimerization', 'Protein Structure, Secondary', 'Protein Structure, Tertiary', 'Signal Transduction', 'bcl-2 Homologous Antagonist-Killer Protein... | 22,015,607 | [['B01.050'], ['G04.146.954.035'], ['A11.251.210.172'], ['D08.244.286.100', 'D12.776.422.220.286.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.409'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.150.900.649.313.992.635.505.500.550.455', 'B01.050.150.900.649.313.992.6... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Minimum displacement thresholds for binocular three-dimensional motion. | Thresholds for the detection of motion in depth in the median plane of the head are substantially poorer than those for motion in the frontoparallel plane. This suggests the existence of two independent mechanisms for their detection. Any three-dimensional (3-D) motion can be decomposed into components of motion in the... | ['Depth Perception', 'Discrimination, Psychological', 'Female', 'Humans', 'Models, Psychological', 'Motion Perception', 'Photic Stimulation', 'Psychophysics', 'Sensory Thresholds', 'Vision, Binocular'] | 11,888,537 | [['F02.463.593.200', 'F02.463.593.778.255'], ['F02.463.593.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.695'], ['F02.463.593.932.567'], ['E05.723.729'], ['E01.370.685', 'F04.096.753'], ['F02.463.593.710'], ['F02.463.593.932.885']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
LiSEQ - whole-genome sequencing of a cross-sectional survey of Listeria monocytogenes in ready-to-eat foods and human clinical cases in Europe. | We present the LiSEQ (Listeria SEQuencing) project, funded by the European Food Safety Agency (EFSA) to compare Listeria monocytogenes isolates collected in the European Union from ready-to-eat foods, compartments along the food chain (e.g. food-producing animals, food-processing environments) and humans. In this artic... | ['Animals', 'Cross-Sectional Studies', 'Dairy Products', 'Drug Resistance, Bacterial', 'Europe', 'Fish Products', 'Food Handling', 'Food Microbiology', 'Genetic Variation', 'Humans', 'Listeria monocytogenes', 'Listeriosis', 'Meat Products', 'Virulence', 'Whole Genome Sequencing'] | 30,775,964 | [['B01.050'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.300.350', 'J02.500.350'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['Z01.542'], ['G07.203.300.600.875.400', 'J02.500.600.875.400'], ['J01.576.423.200'], ['H01.158.273.540.274.332', 'J01.576.423.850.7... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Cellular responses to neurotoxic compounds of environmental significance. | Many neurotoxic chemicals of environmental significance can be conveniently classified according to their cellular site of action in the nervous system. This paper considers neurotoxins which damage the nerve cell body (neuronopathy), its axonal process (axonopathy), or the myelin sheath which segmentally enwraps the m... | ['Animals', 'Axons', 'Environmental Pollutants', 'Nerve Fibers, Myelinated', 'Nervous System', 'Neurons'] | 299,578 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chromosomal mapping of repetitive DNAs in Gobionellus oceanicus and G. stomatus (Gobiidae; Perciformes): A shared XX/XY system and an unusual distribution of 5S rDNA sites on the Y chromosome. | With nearly 2,000 species, Gobiidae is the most specious family of the vertebrates. This high level of speciation is accompanied by conspicuous karyotypic modifications, where the role of repetitive sequences remains largely unknown. This study analyzed the karyotype of 2 species of the genus Gobionellus and mapped 18S... | ['Animals', 'Chromosome Mapping', 'DNA, Ribosomal', 'Evolution, Molecular', 'Female', 'Genetic Variation', 'Karyotype', 'Male', 'Perciformes', 'RNA, Ribosomal, 18S', 'RNA, Ribosomal, 5S', 'Repetitive Sequences, Nucleic Acid', 'X Chromosome', 'Y Chromosome'] | 25,720,317 | [['B01.050'], ['E05.393.183'], ['D13.444.308.475'], ['G05.045.250', 'G16.075.250'], ['G05.365'], ['G05.360.162.679'], ['B01.050.150.900.493.602'], ['D13.444.735.686.675'], ['D13.444.735.686.650'], ['G02.111.570.080.708', 'G05.360.080.708'], ['A11.284.187.865.982', 'G05.360.162.865.982'], ['A11.284.187.865.983', 'G05.36... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transition to capitation. Core competencies for physician practice success. | The growth of managed care--with the resulting consolidation, cost control, and profit-oriented players entering the market--is a major source of concern. Largely due to this market evolution, physicians find themselves in the position of working within a single management paradigm and attempting to apply it in two dif... | ['Attitude of Health Personnel', 'Capitation Fee', 'Fee-for-Service Plans', 'Managed Care Programs', 'Practice Management, Medical', "Practice Patterns, Physicians'", 'Professional Competence', 'United States', 'Workforce'] | 10,164,292 | [['F01.100.050', 'N05.300.100'], ['N03.219.442.090'], ['N03.219.442.195', 'N03.219.521.710.305.090', 'N04.452.758.745.225'], ['N03.219.521.576.343.800', 'N04.590.374.410'], ['N04.452.758.708.450'], ['N04.590.374.577', 'N05.300.625'], ['I02.399.630'], ['Z01.107.567.875'], ['N04.452.525']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[Endoscopic and surgical therapy of hemorrhagic duodenal and stomach ulcer]. | The aim of this prospective clinical study was to evaluate whether a combination of the endoscopic hemostasis together with fibrin sealing and consecutive conservative therapy could reduce the frequency of recurrent bleedings, thus the number of operations without adversely influencing the prognosis of the disease. 134... | ['Adult', 'Aged', 'Aged, 80 and over', 'Combined Modality Therapy', 'Duodenal Ulcer', 'Endoscopy, Digestive System', 'Epinephrine', 'Female', 'Fibrin Tissue Adhesive', 'Hospital Mortality', 'Humans', 'Male', 'Middle Aged', 'Peptic Ulcer Hemorrhage', 'Postoperative Complications', 'Prognosis', 'Prospective Studies', 'Re... | 7,634,943 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.186'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['E01.370.372.250', 'E01.370.388.250.250', 'E04.210.240', 'E04.502.250.250'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Recurrent mutations in the COL1A2 gene in patients with osteogenesis imperfecta. | A new recurrent point mutation in the COL1A2 gene was found in a patient with type III osteogenesis imperfecta (OI). A G-to-T transversion in nucleotide position 1121 leads to an amino acid substitution Gly238Cys. This is the first report on the most N-terminal cysteine substitution in COL1A2 reported so far. Until now... | ['Amino Acid Substitution', 'Base Sequence', 'Child', 'Child, Preschool', 'Collagen', 'DNA Mutational Analysis', 'DNA, Complementary', 'Female', 'Humans', 'Osteogenesis Imperfecta', 'Point Mutation'] | 11,359,465 | [['E05.393.420.601.035', 'G05.558.109'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['M01.060.406'], ['M01.060.406.448'], ['D05.750.078.280', 'D12.776.860.300.250'], ['E05.393.760.700.300'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['B01.050.150.900.649.313.988.400.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Mixed cultures of avian blastoderm cells and the quail mesoderm cell line QCE-6 provide evidence for the pluripotentiality of early mesoderm. | During the early stages of embryogenesis, the mesoderm gives rise to cells of the cardiovascular system which include cardiac myocytes and vascular endothelial and red blood cells. We have investigated the development of these cell phenotypes using aggregate cultures of avian blastoderm cells, which replicated mesoderm... | ['Animals', 'Blastoderm', 'Cell Differentiation', 'Cell Line', 'Cells, Cultured', 'Chick Embryo', 'Coculture Techniques', 'Coturnix', 'Endothelial Growth Factors', 'Endothelium, Vascular', 'Erythrocytes', 'Erythropoiesis', 'Erythropoietin', 'Fibroblast Growth Factor 2', 'Genes, Reporter', 'Heart', 'Lymphokines', 'Mesod... | 9,398,432 | [['B01.050'], ['A16.331.024'], ['G04.152'], ['A11.251.210'], ['A11.251'], ['A13.350.150', 'A16.331.200'], ['E05.481.500.374'], ['B01.050.150.900.248.350.650.350'], ['D12.644.276.390', 'D12.776.467.390', 'D23.529.390'], ['A07.015.700.500', 'A10.272.491.355'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G04.152.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anthocyanidin Extract from Summer-black-grape Affects the Expression of Ki-67 in Testis, Ovary of D-Galactose-induced Aging Mice. | The aim of this work was to analyze the expression of Ki-67 in ovary, testis of aging mice with anthocyanidin extract from Summer-black-grape. ICR mice (the aging group and the anthocyanidin-groups (50 mg/kg/D-group, 75 mg/kg/D-group and 100 mg/kg/D-group) were employed to evaluate the effect of grape anthocyanidin on ... | ['Aging', 'Animals', 'Anthocyanins', 'Female', 'Free Radical Scavengers', 'Galactose', 'Gene Expression', 'Ki-67 Antigen', 'Male', 'Mice, Inbred ICR', 'Models, Animal', 'Ovary', 'Testis', 'Vitis'] | 32,249,264 | [['G07.345.124'], ['B01.050'], ['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['D27.505.519.217.500'], ['D09.947.875.359.377'], ['G05.297'], ['D12.776.660.625.500', 'D23.050.290.500', 'D23.101.140.400'], ['B01.050.050.199.520.520.510', 'B01.050.150.900.649.313.992.635.505.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Murine heterotopic heart transplant technique. | It is now over forty years since this technique was first reported by Corry, Wynn and Russell. Although it took some years for other labs to become proficient in and utilize this technique, it is now widely used by many laboratories around the world. A significant refinement to the original technique was developed and ... | ['Animals', 'Heart Transplantation', 'Mice', 'Models, Animal', 'Transplantation Immunology', 'Transplantation, Heterotopic'] | 25,046,118 | [['B01.050'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.598'], ['G12.875'], ['E04.936.800']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association between DNA methylation of the KITLG gene and cortisol levels under stress: a replication study. | A recent study reported for the first time, that DNA methylation of the KITLG gene mediates the association between childhood trauma and cortisol stress reactivity. Our study aimed to provide the first independent replication of these findings. ESPRIT is a prospective study of community-dwelling participants (age ? 65)... | ['Child', 'DNA Methylation', 'Female', 'Humans', 'Hydrocortisone', 'Hypothalamo-Hypophyseal System', 'Male', 'Pituitary-Adrenal System', 'Prospective Studies', 'Saliva', 'Stem Cell Factor', 'Stress, Psychological', 'Surveys and Questionnaires'] | 30,298,755 | [['M01.060.406'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['A06.688.357', 'A08.186.211.180.497.352.435', 'A08.186.211.200.317.357.352.435', 'A08.713.357']... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Atrioventricular (AV) node vagal stimulation by transvenous permanent lead implantation to modulate AV node function: safety and feasibility in humans. | BACKGROUND: Atrioventricular (AV) node vagal stimulation (AVNVS) has recently emerged as a novel approach to controlling AV dromotropic function. Animal studies have demonstrated that selective epicardial AVNVS is effective in controlling ventricular rate (VR) acutely and in the long term. Endocardial AVNVS has been sh... | ['Angioplasty, Balloon, Coronary', 'Atrial Fibrillation', 'Atrioventricular Node', 'Cardiac Pacing, Artificial', 'Defibrillators, Implantable', 'Electrodes, Implanted', 'Endocardium', 'Equipment Safety', 'Feasibility Studies', 'Heart Failure', 'Heart Rate', 'Humans', 'Male', 'Middle Aged', 'Reproducibility of Results',... | 19,716,083 | [['E02.148.050.060.100', 'E04.100.376.719.100', 'E04.100.814.529.124.060.100', 'E04.100.814.529.968.050', 'E04.502.382.124.060.100', 'E04.502.382.968.050', 'E04.928.220.520.100', 'E05.157.016.060.100'], ['C14.280.067.198', 'C23.550.073.198'], ['A07.541.409.147'], ['E02.331.200'], ['E07.305.250.159.175', 'E07.305.250.31... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Development of the Brussels Infant and Toddler Stool Scale ('BITSS'): protocol of the study. | INTRODUCTION: The Bristol Stool Form Scale (BSS) which consists of 7 photographs of different stool forms allows assessment of stool consistency (scale 1 for hard lumps to scale 7 for watery stools), in an objective manner in adults. The BSS is also sometimes used to characterise the stools of infants and young childre... | ['Child, Preschool', 'Defecation', 'Feces', 'Gastroenterology', 'Health Status Indicators', 'Humans', 'Infant', 'Observer Variation', 'Photography'] | 28,360,250 | [['M01.060.406.448'], ['G10.261.165'], ['A12.459'], ['H02.403.429.405'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E01.37... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[Continuous positive airway pressure (CPAP) with face mask to treat acute respiratory failure]. | OBJECTIVE: To evaluate the efficacy of continuous positive airway pressure (CPAP) administered by face mask in patients with acute respiratory failure with indication of mechanical ventilation.MATERIALS AND METHOD: Eleven patients (mean age 41.3 years) in acute respiratory failure were admitted in the Respiratory Unit-... | ['Acute Disease', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Blood Gas Analysis', 'Blood Pressure', 'Female', 'Heart Rate', 'Humans', 'Male', 'Masks', 'Middle Aged', 'Positive-Pressure Respiration', 'Respiratory Insufficiency'] | 9,497,542 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Clinical Utility of the Meal Tolerance Test in the Care of Patients with Type 2 Diabetes Mellitus. | Objective The measurement of C-peptide immunoreactivity (CPR) is essential for evaluating the pancreatic â-cell function and selecting appropriate therapeutic agents in patients with diabetes mellitus. The meal tolerance test (MTT) is simple to administer physiological insulin-stimulating test. Previous studies have re... | ['Adult', 'Biomarkers', 'Blood Glucose', 'Body Mass Index', 'C-Peptide', 'Diabetes Mellitus, Type 2', 'Diagnostic Techniques, Endocrine', 'Female', 'Glucose Tolerance Test', 'Humans', 'Hypoglycemic Agents', 'Insulin', 'Insulin-Secreting Cells', 'Male', 'Meals', 'Meat', 'Middle Aged', 'Postprandial Period'] | 32,938,850 | [['M01.060.116'], ['D23.101'], ['D09.947.875.359.448.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['C18.452.394.750.149', 'C19.246.300'], ['E01.370.374'], ['E01.370.225.124.100.355', 'E01.370.374.355'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Molecular Analysis of the B Microchromosome in Steindachnerina insculpta (Characiformes: Curimatidae) by Microdissection. | B chromosomes are additional elements to standard karyotypes observed in different species of fishes, especially in Curimatidae. However, despite studies demonstrating the occurrence of Bs, little is known about their origin and evolution. To better understand the genomic composition and evolutionary processes involvin... | ['Animals', 'Base Sequence', 'Characiformes', 'Chromosome Painting', 'Chromosomes', 'Evolution, Molecular', 'Female', 'Male', 'Molecular Sequence Data', 'Retroelements', 'Sequence Analysis, DNA'] | 25,999,244 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.150.900.493.130'], ['E01.370.225.500.620.670.325.350.125', 'E01.370.225.750.600.670.325.350.125', 'E05.200.500.620.670.325.350.125', 'E05.200.750.600.670.325.350.125', 'E05.393.285.350.125', 'E05.393.661.475.350.125'], ['A11.284.187', 'A... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A cadaveric study in the Indian population of the brachialis muscle innervation by the radial nerve. | Radial nerve innervation to the brachialis muscle has been studied previously by different authors in Caucasian, Chinese, and Thai population. Present study was aimed to describe the radial nerve and musculocutaneous nerve contribution to the brachialis muscle and to elucidate racial differences between Indian and othe... | ['Brachial Plexus', 'Cadaver', 'Embalming', 'Female', 'Humans', 'India', 'Male', 'Muscle, Skeletal', 'Radial Nerve', 'Skin'] | 19,221,655 | [['A08.800.800.720.050'], ['C23.550.260.224'], ['I01.076.201.450.550.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['A02.633.567', 'A10.690.552.500'], ['A08.800.800.720.050.700'], ['A17.815']] | ['Anatomy [A]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
CXCR2-positive neutrophils are essential for cuprizone-induced demyelination: relevance to multiple sclerosis. | Multiple sclerosis is an inflammatory demyelinating disorder of the CNS. Recent studies have suggested diverse mechanisms as underlying demyelination, including a subset of lesions induced by an interaction between metabolic insult to oligodendrocytes and inflammatory mediators. For mice of susceptible strains, cuprizo... | ['Animals', 'Chimera', 'Corpus Callosum', 'Cuprizone', 'Demyelinating Diseases', 'Disease Models, Animal', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Mice, Transgenic', 'Monoamine Oxidase Inhibitors', 'Multiple Sclerosis', 'Myelin Proteins', 'Myelin Sheath', 'Neutrophils', 'Oligodendroglia', 'RNA, Messenger', 'Re... | 20,154,684 | [['B01.050'], ['B05.200'], ['A08.186.211.200.885.800.750'], ['D02.455.426.392.368.367.190'], ['C10.314'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.500.500', 'B01.050.1... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cervical ICA pseudo-occlusion on single phase CTA in patients with acute terminal ICA occlusion: what is the mechanism and can delayed CTA aid diagnosis? | BACKGROUND: Single-phase CT angiography (CTA) forms the basis of hyperacute stroke imaging but many patients with terminal internal carotid artery (ICA) occlusion exhibit a pseudo-occlusion of the cervical ICA whereby a column of unopacified blood mimics a tandem cervical ICA lesion. We aimed to investigate the utility... | ['Adult', 'Aged', 'Angiography, Digital Subtraction', 'Arterial Occlusive Diseases', 'Carotid Artery Diseases', 'Carotid Artery, Internal', 'Computed Tomography Angiography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Stroke', 'Thrombectomy', 'Time Factors'] | 29,438,036 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.350.600.350.700.060', 'E01.370.350.700.060.060', 'E01.370.350.700.700.060', 'E01.370.350.760.060', 'E01.370.370.050.060'], ['C14.907.137'], ['C10.228.140.300.200', 'C14.907.253.123'], ['A07.015.114.186.200.230'], ['E01.370.350.350.810.335', 'E01.370.350.567.250', 'E01.37... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bacterial birth scar proteins mark future flagellum assembly site. | Many prokaryotic protein complexes underlie polar asymmetry. In Caulobacter crescentus, a flagellum is built exclusively at the pole that arose from the previous cell division. The basis for this pole specificity is unclear but could involve a cytokinetic birth scar that marks the newborn pole as the flagellum assembly... | ['Bacterial Proteins', 'Caulobacter crescentus', 'Cell Movement', 'Cell Polarity', 'Cytokinesis', 'Cytoskeletal Proteins', 'Flagella', 'Mutation', 'Recombinant Fusion Proteins'] | 16,530,048 | [['D12.776.097'], ['B03.440.400.280.280', 'B03.440.400.425.288.100.100', 'B03.660.050.090.100.100'], ['G04.198', 'G07.568.500.180'], ['G04.250'], ['G04.144.220.250'], ['D12.776.220'], ['A11.284.180.290'], ['G05.365.590'], ['D12.776.828.300']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Production and characterization of a monoclonal antibody against mannose-sensitive hemagglutinin of Vibrio cholerae. | We have generated murine monoclonal antibodies (MAb) against Vibrio cholerae mannose-sensitive hemagglutinin (MSHA) using conventional hybridoma procedures. Seven hybridomas were obtained and one characterized. Hybridoma 2F12/F1 secreted an antibody of the IgG3 type that reacted with a 17-kDa antigen corresponding to t... | ['Animals', 'Antibodies, Bacterial', 'Antibodies, Monoclonal', 'Bacterial Proteins', 'Chickens', 'Enzyme-Linked Immunosorbent Assay', 'Fimbriae Proteins', 'Hemagglutination Tests', 'Hemagglutinins', 'Hybridomas', 'Immunoblotting', 'Mannose', 'Mannose-Binding Lectin', 'Vibrio cholerae'] | 9,523,239 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.097'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.478.566.350.170', 'E05.478.56... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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