Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Elimination of iatrogenic impotence and improvement of sexual function after aortoiliac revascularization. | One hundred ten men who underwent revascularization for aortoiliac occlusive disease by either aortic reconstruction (n = 66), crossover femorofemoral bypass (n = 38), or axillofemoral bypass (n = 6) were examined with regard to preoperative and postoperative sexual function. Aortic reconstructions were performed using... | ['Adult', 'Aged', 'Aorta', 'Aortic Aneurysm', 'Arterial Occlusive Diseases', 'Erectile Dysfunction', 'Female', 'Femoral Artery', 'Humans', 'Iliac Artery', 'Male', 'Methods', 'Middle Aged', 'Postoperative Complications', 'Sexual Dysfunction, Physiological'] | 7,200,349 | [['M01.060.116'], ['M01.060.116.100'], ['A07.015.114.056'], ['C14.907.055.239', 'C14.907.109.139'], ['C14.907.137'], ['C12.294.644.486', 'F03.835.400'], ['A07.015.114.351'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.444'], ['E05.581'], ['M01.060.116.630'], ['C23.550.767'], ['C12.294.644', 'C13.351.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of lindane on terrestrial invertebrates. | Acute and chronic ecotoxicity tests with lindane were carried out using the soil invertebrates Eisenia fetida, Enchytraeus albidus, and Folsomia candida. To assess the influence of soil type on the bioavailability, these tests were carried out in a standard artificial OECD soil and in sandy and loamy field soil. For ea... | ['Animals', 'Biological Availability', 'Hexachlorocyclohexane', 'Insecta', 'Insecticides', 'No-Observed-Adverse-Effect Level', 'Oligochaeta', 'Population Dynamics', 'Risk Assessment', 'Soil Pollutants', 'Solubility'] | 11,815,813 | [['B01.050'], ['G03.787.151', 'G07.690.725.129'], ['D02.455.526.439.600'], ['B01.050.500.131.617'], ['D27.720.031.700.491', 'D27.888.723.491'], ['E05.940.600', 'G07.690.936.750'], ['B01.050.500.091.657'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
A side reaction of alanine racemase: transamination of cycloserine. | Alanine racemase (EC 5.1.1.1) catalyzes the interconversion of alanine enantiomers, and thus represents the first committed step involved in bacterial cell wall biosynthesis. Cycloserine acts as a suicide inhibitor of alanine racemase and as such, serves as an antimicrobial agent. The chemical means by which cycloserin... | ['Alanine Racemase', 'Catalytic Domain', 'Crystallography, X-Ray', 'Cycloserine', 'Enzyme Inhibitors', 'Geobacillus stearothermophilus', 'Kinetics', 'Models, Molecular', 'Protein Conformation', 'Spectrophotometry', 'Static Electricity', 'Stereoisomerism'] | 12,741,835 | [['D08.811.399.894.200.200'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.196.309.742.225'], ['D03.383.129.385.162', 'D03.383.129.462.600.162', 'D12.125.154.800.750'], ['D27.505.519.389'], ['B03.300.390.400.158.400.400', 'B03.353.500.100.400.400', 'B03.510.100.100.400.400', 'B03.510.415.400.158.40... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of ultrafine carbon black particles on lipoteichoic acid-induced early pulmonary inflammation in BALB/c mice. | We studied the interaction effects of a single intratracheal instillation of ultrafine carbon black (CB) particles and staphylococcal lipoteichoic acid (LTA) on early pulmonary inflammation in male BALB/c mice. We examined the cellular profile, cytokine and chemokine levels in the bronchoalveolar lavage (BAL) fluid, an... | ['Animals', 'Bronchoalveolar Lavage Fluid', 'Carbon', 'Cytokines', 'Drug Synergism', 'Gene Expression Regulation', 'Lipopolysaccharides', 'Lung', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Neutrophils', 'Particle Size', 'Pneumonia', 'RNA, Messenger', 'Teichoic Acids', 'Toll-Like Receptor 2', 'Toll-Like Receptor 4'] | 16,387,335 | [['B01.050'], ['E05.927.100.500'], ['D01.268.150'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G07.690.773.968.477'], ['G05.308'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['A04.411'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.52... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Studies on the pharmacokinetics and mutagenic potential of rhodamine B. | Rhodamine B is used as a marker dye in herbicide sprays. There is evidence that spray operators and others may absorb rhodamine B through the skin. This study was undertaken to investigate the in vivo mutagenicity of rhodamine B, to compare the in vitro mutagenicity of two commercial preparations of the dye with that o... | ['Adult', 'Animals', 'Chromatography, High Pressure Liquid', 'Dose-Response Relationship, Drug', 'Female', 'Humans', 'Injections, Intravenous', 'Male', 'Mutagenicity Tests', 'Rabbits', 'Rhodamines', 'Skin Absorption', 'Xanthenes'] | 2,381,022 | [['M01.060.116'], ['B01.050'], ['E05.196.181.400.300'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['E05.393.560', 'E05.940.560'], ['B01.050.150.900.649.313.968.700'], ['D03.633.300.953.600'], ['G03.015.500.750', 'G03.787.024.... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ticks and mosquitoes as vectors of Borrelia burgdorferi s. l. in the forested areas of Szczecin. | The aim of the study was to determine the infection level of adult forms and larvae of ticks and mosquitoes with Borrelia burgdorferi in the forested areas of Szczecin. A total of 1699 ticks Ixodes ricinus, including 1422 nymphs, 277 adult forms and 2862 mosquito females representing the genera Aedes (89.6%) and Culex ... | ['Animals', 'Borrelia burgdorferi', 'Culicidae', 'Female', 'Insect Vectors', 'Male', 'Poland', 'Ticks'] | 18,274,258 | [['B01.050'], ['B03.440.425.410.711.193.150.125', 'B03.851.595.193.150.125'], ['B01.050.500.131.617.720.500.500.750.712.500.875'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['Z01.542.248.679'], ['B01.050.500.131.166.132.832']] | ['Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Porous hydroxyapatite as a bone graft substitute in cranial reconstruction: a histometric study. | To assess the potential of a porous hydroxyapatite matrix to serve as a bone graft substitute, bilateral 15 X 20 mm craniectomy defects were reconstructed in 17 dogs with blocks of implant and split-rib autografts. Specimens were retrieved at 3, 6, 12, 24, and 48 months, and undecalcified sections were prepared for mic... | ['Animals', 'Dogs', 'Durapatite', 'Hydroxyapatites', 'Prostheses and Implants', 'Ribs', 'Skull', 'Surgery, Plastic', 'Wound Healing'] | 2,834,761 | [['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['D01.029.260.700.675.374.075.025.300', 'D01.146.360.050.300', 'D01.578.122.477', 'D01.695.625.675.650.075.025.300'], ['E07.695... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Cushing disease in children and adolescents - assessment of the clinical course, diagnostic process, and effects of the treatment - experience from a single paediatric centre. | INTRODUCTION: Adrenocorticotropic hormone-dependent Cushing syndrome, known as Cushing disease (CD), is a rare disease in paediatric patients, the signs and symptoms of which differ from those seen in adult patients.AIM OF THE STUDY: The objective of the study was to present the diagnostics and treatment results of CD ... | ['Adenoma', 'Adolescent', 'Child', 'Female', 'Glucocorticoids', 'Humans', 'Pituitary ACTH Hypersecretion', 'Pituitary Neoplasms', 'Retrospective Studies', 'Treatment Outcome'] | 31,769,271 | [['C04.557.470.035'], ['M01.060.057'], ['M01.060.406'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.617.738.250.725', 'C19.700.355.800'], ['C04.588.322.609', 'C04.588.614.250.195.885.500.600', 'C10.228.140.211.885.500.600', 'C10.228.140.617.477.600', 'C... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Safety and immunogenicity of Shigella sonnei and Shigella flexneri 2a O-specific polysaccharide conjugates in children. | O-specific polysaccharide conjugates of shigellae were safe and immunogenic in young adults, and a Shigella sonnei conjugate conferred protection [1-3]. Shigellosis is primarily a disease of children; therefore, the safety and immunogenicity of S. sonnei and Shigella flexneri 2a conjugates were studied in 4- to 7-year-... | ['Antibodies, Bacterial', 'Antibody Specificity', 'Bacterial Vaccines', 'Child', 'Child, Preschool', 'Dysentery, Bacillary', 'Humans', 'Immunoconjugates', 'Immunoglobulin Isotypes', 'O Antigens', 'Shigella', 'Shigella flexneri', 'Shigella sonnei', 'Vaccination'] | 10,228,084 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['G12.100'], ['D20.215.894.135'], ['M01.060.406'], ['M01.060.406.448'], ['C01.150.252.400.310.229', 'C06.405.205.331.479', 'C06.405.469.300.479'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.790.651.114.58... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enteroaggregative Escherichia coli is a cause of acute diarrheal illness: a meta-analysis. | BACKGROUND: Conflicting studies exist regarding the role of enteroaggregative Escherichia coli (EAEC) as a cause of acute diarrheal illness. The objective of this meta-analysis was to determine whether identification of EAEC in stool samples is associated with acute diarrheal illness among different subpopulations, by ... | ['Escherichia coli Infections', 'Humans', 'Odds Ratio', 'Risk Factors'] | 16,886,146 | [['C01.150.252.400.310.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.750.625.590', 'N06.850.520.830.600.600'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Role of Slingshot-1L in peripheral eosinophils of asthmatic patients]. | OBJECTIVE: To investigate the expression of Slingshot-1L (SSH-1L) in peripheral blood eosinophils of asthmatic patients.METHODS: Peripheral vein blood sample of 30 ml was collected from 15 healthy volunteers, 15 asthmatic patients with glucocorticoid treatment and 15 asthmatic patients without the treatment. The eosino... | ['Actin Depolymerizing Factors', 'Actins', 'Adult', 'Asthma', 'Blotting, Western', 'Eosinophils', 'Female', 'Humans', 'Male', 'Middle Aged', 'Phosphoprotein Phosphatases', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction'] | 17,259,100 | [['D05.750.078.730.212', 'D12.776.220.525.212'], ['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.11... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Decrease in the urine cotinine concentrations of Korean non-smokers between 2009 and 2011 following implementation of stricter smoking regulations. | This study aimed to determine if there was an association between the implementation of smoking regulation policies and the urine cotinine concentrations of Korean non-smokers. The subjects of this study were 4612 non-smoking Korean citizens (aged 19 or older) selected from the first stage of the Korean National Enviro... | ['Adult', 'Aged', 'Cotinine', 'Female', 'Gas Chromatography-Mass Spectrometry', 'Government Regulation', 'Humans', 'Male', 'Middle Aged', 'Republic of Korea', 'Smoking', 'Smoking Cessation', 'Smoking Prevention', 'Young Adult'] | 26,507,969 | [['M01.060.116'], ['M01.060.116.100'], ['D03.383.773.812.180'], ['E05.196.181.349.500', 'E05.196.566.500'], ['I01.880.604.394', 'N03.706.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.252.474.557.750'], ['F01.145.805'], ['F01.145.488.732'], ['I02.233.332.812', 'N02.421.726.407.840'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Origin and function of adherent lymphokine activated killer cells in patients with chronic myeloid leukaemia who relapse following bone marrow transplantation. | Adherent lymphokine activated killer (ALAK) cells are a subpopulation of activated natural killer (NK) cells with MHC unrestricted antitumour activity distinguished by their propensity to adhere to plastic in the presence of interleukin-2 (IL-2). We generated ALAK cells from seven patients with chronic myeloid leukaemi... | ['Antigens, Neoplasm', 'Antigens, Surface', 'Bone Marrow Transplantation', 'Cytotoxicity, Immunologic', 'Female', 'Humans', 'Karyotyping', 'Killer Cells, Lymphokine-Activated', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Male', 'Recurrence'] | 1,998,598 | [['D23.050.285'], ['D23.050.301'], ['E02.095.147.725.040', 'E04.936.580.040'], ['G12.287'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['A11.118.637.555.283.500', 'A11.118.637.555.567.537.500', 'A15.145.229.637.555.283.500',... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Results of a cooperative educational program to improve prostate pathology reports among patients undergoing radical prostatectomy. | The information contained in pathology reports of radical prostatectomy specimens is critically important to treating physicians for the selection of adjuvant therapy, the evaluation of therapy, estimating prognosis, and analyzing outcomes. This information is also important to patients and their families. The first ph... | ['Adenocarcinoma', 'Aged', 'Documentation', 'Education, Medical, Continuing', 'Feedback', 'Humans', 'Laboratories, Hospital', 'Male', 'Medical Audit', 'Medical Records', 'Medicare', 'Middle Aged', 'New York', 'Pathology Department, Hospital', 'Pathology, Surgical', 'Professional Review Organizations', 'Prostatectomy', ... | 11,845,938 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['L01.453.245'], ['I02.358.212.350', 'I02.358.399.250'], ['L01.906.394.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.216.500.968.420', 'N02.278.487.410', 'N04.452.442.452.422.420'], ['N04.761.700.250.500', 'N05.700.175.500'], ['E05.318.308.940.968', 'N0... | ['Diseases [C]', 'Named Groups [M]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Molecular characterization of Clostridium perfringens strains isolated from diseased turkeys in Italy. | One hundred and six Clostridium perfringens field strains, isolated from diseased turkeys in Italy between 2006 and 2015, were toxinotyped by polymerase chain reaction. Strains were derived from intestines (87), livers (17) and subcutaneous tissues (2). In addition to the four major toxins, strains were also screened f... | ['Animals', 'Bacterial Toxins', 'Clostridium Infections', 'Clostridium perfringens', 'Coccidiosis', 'Enteritis', 'Enterotoxins', 'Intestines', 'Italy', 'Necrosis', 'Poultry Diseases', 'Turkeys'] | 26,950,690 | [['B01.050'], ['D23.946.123'], ['C01.150.252.410.222'], ['B03.300.390.400.200.575', 'B03.353.625.375.500.575', 'B03.510.415.400.200.575'], ['C01.610.752.250'], ['C06.405.205.462', 'C06.405.469.326'], ['D23.946.330'], ['A03.556.124'], ['Z01.542.489'], ['C23.550.717'], ['C22.131.728'], ['B01.050.150.900.248.350.800', 'B0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Physicochemical and transfection properties of cationic Hydroxyethylcellulose/DNA nanoparticles. | In this study the physicochemical and transfection properties of cationic hydroxyethylcellulose/plasmid DNA (pDNA) nanoparticles were investigated and compared with the properties of DNA nanoparticles based on polyethylene imine (PEI), which is widely investigated as a gene carrier. The two types of cationic hydroxyeth... | ['Animals', 'Biocompatible Materials', 'Biotechnology', 'COS Cells', 'Cations', 'Cell Survival', 'Cellulose', 'Chemistry, Physical', 'Chlorocebus aethiops', 'DNA', 'HeLa Cells', 'Humans', 'Macromolecular Substances', 'Nanoparticles', 'Transfection'] | 17,025,362 | [['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['H01.158.550', 'J01.897.120'], ['A11.251.210.172.500', 'A11.329.228.220'], ['D01.248.497.300'], ['G04.346'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['H01.181.529'], ['B01.050.150.900.649.313.988.400.112.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Proteomic analysis of enterotoxigenic Escherichia coli (ETEC) in neutral and alkaline conditions. | BACKGROUND: Enterotoxigenic Escherichia coli (ETEC) is a major cause of diarrhea in children and travelers to endemic areas. Secretion of the heat labile AB5 toxin (LT) is induced by alkaline conditions. In this study, we determined the surface proteome of ETEC exposed to alkaline conditions (pH 9) as compared to neutr... | ['Adenosine Triphosphatases', 'Amino Acids', 'Bacterial Outer Membrane Proteins', 'Bacterial Toxins', 'Down-Regulation', 'Electron Transport', 'Enterotoxigenic Escherichia coli', 'Enterotoxins', 'Escherichia coli Infections', 'Escherichia coli Proteins', 'Gene Expression Regulation, Bacterial', 'Hydrogen-Ion Concentrat... | 28,061,865 | [['D08.811.277.040.025'], ['D12.125'], ['D12.776.097.120', 'D12.776.543.100'], ['D23.946.123'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G02.111.248', 'G03.295.531.403', 'G03.493.350'], ['B03.440.450.425.325.300.340', 'B03.660.250.150.180.100.340'], ['D23.946.330'], ['C01.150.252.400.310.330'], ['D12.776.09... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A comparison of field and laboratory polygraphs in the detection of deception. | This study compared the effectiveness of field and laboratory polygraphs in discriminating guilty and innocent subjects tested using the Control Question Technique (CQT). Subjects were 48 prisoners examined regarding a mock theft in a peer threat context; physiological responses were recorded simultaneously on a Lafaye... | ['Adult', 'Antisocial Personality Disorder', 'Arousal', 'Guilt', 'Humans', 'Lie Detection', 'Male', 'Monitoring, Physiologic', 'Prisoners', 'Psychophysiology'] | 1,816,590 | [['M01.060.116'], ['F03.675.050'], ['F02.830.104', 'G11.561.035'], ['F01.470.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.784.240.514', 'F02.830.512', 'I01.198.780.937.619'], ['E01.370.520'], ['M01.729'], ['E02.190.525.812', 'F02.830', 'F04.096.795', 'H01.158.782.795']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
Antitrypanosomal action enhanced by photoaffinity labeling with ethidium analogs. | The trypanocidal activity of photoreactive azido analogs of ethidium was tested to determine the suitability of using such compounds as in vivo probes to study the mechanism of the antitrypanosomal activity of ethidium. Eight ethidium analogs, including three nonphotoreactive compounds, were tested for their ability to... | ['Animals', 'Chemical Phenomena', 'Chemistry', 'Ethidium', 'Light', 'Male', 'Mice', 'Photolysis', 'Structure-Activity Relationship', 'Trypanosoma brucei brucei'] | 7,264,832 | [['B01.050'], ['G02'], ['H01.181'], ['D03.633.300.633.416'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['B01.050.150.900.649.313.992.635.505.500'], ['G02.740.685'], ['G02.111.830', 'G07.690.773.997'], ['B01.268.475.868.887.080']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
From probation to prevention: protecting college students and workers from animal hazards. | OBJECTIVE: Our objective was to develop an organized system to assess individual and group exposure to animal hazards on a college campus.MAIN POINTS: The scope and complexity of college health services continue to expand as campuses confront unforeseen exposures and disease entities. Of great concern are students and ... | ['Animals', 'Animals, Laboratory', 'Health Promotion', 'Humans', 'Occupational Exposure', 'Student Health Services', 'Students', 'Universities'] | 17,017,307 | [['B01.050'], ['B01.050.050.199'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.460.350.600'], ['N02.421.897'], ['M01.848'], ['I02.783.830', 'J03.832.830']] | ['Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
Preoperative staging of rectal carcinoma by endorectal ultrasound: is there a learning curve? | BACKGROUND AND AIMS: Endorectal ultrasound (ERUS) is becoming an essential tool in the management of rectal cancer. However, accuracy in the assessment of disease staging may be dependent on operator experience. The aim of this study was to determine if a learning curve exists.MATERIALS AND METHODS: From October 1999 t... | ['Aged', 'Carcinoma', 'Endosonography', 'Female', 'Humans', 'Learning', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Observer Variation', 'Preoperative Care', 'Rectal Neoplasms', 'Sensitivity and Specificity'] | 17,294,198 | [['M01.060.116.100'], ['C04.557.470.200'], ['E01.370.350.850.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['E01.789.625'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['E... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Plasma nitric oxide end products are increased in the ischemic canine heart. | Coronary arteriovenous difference in stable end-products of nitric oxide metabolism, nitrate and nitrite, was increased in ischemic canine hearts. In accordance with the reduction of coronary blood flow by 40, 67, 80 and 100%, the plasma nitrate+nitrite concentration increased from 3.2 +/- 0.6 to 8.7 +/- 1.3, 12.5 +/- ... | ['Animals', 'Arginine', 'Coronary Circulation', 'Coronary Vessels', 'Dogs', 'Hemodynamics', 'Myocardial Ischemia', 'Myocardium', 'NG-Nitroarginine Methyl Ester', 'Nitrates', 'Nitric Oxide', 'Nitrites', 'Oxygen Consumption', 'Time Factors'] | 7,794,246 | [['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['G09.330.100.324'], ['A07.015.114.269', 'A07.015.908.194'], ['B01.050.150.900.649.313.750.250.216.200'], ['G09.330.380'], ['C14.280.647', 'C14.907.585'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D12.125.068.050.525', 'D12.125.095.104.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
T-cell-induced expression of human immunodeficiency virus in macrophages. | Macrophages are major reservoirs of human immunodeficiency virus (HIV) in the tissues of infected humans. As monocytes in the peripheral blood do not show high levels of infection, we have investigated the expression of HIV in T-cell-activated, differentiated macrophages. Peripheral blood mononuclear cells were isolate... | ['Cell Communication', 'Cells, Cultured', 'Gene Products, gag', 'HIV Core Protein p24', 'HIV Seropositivity', 'HIV-1', 'HLA-DR Antigens', 'Humans', 'Lymphocyte Activation', 'Macrophages', 'Monocytes', 'T-Lymphocytes', 'Time Factors', 'Viral Core Proteins'] | 2,112,615 | [['G04.085'], ['A11.251'], ['D12.776.775.330', 'D12.776.964.775.350', 'D12.776.964.970.600.850.350'], ['D12.776.964.775.350.362.500', 'D12.776.964.775.562.750.500', 'D12.776.964.970.600.850.350.362.500', 'D23.050.327.520.300'], ['C01.221.250.875.500', 'C01.221.812.640.400.500', 'C01.778.640.400.500', 'C01.925.782.815.6... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Elective induction of labor: failure to follow guidelines and risk of cesarean delivery. | BACKGROUND: Estimate the frequency of failure to follow the French consensus guidelines for elective induction, and assess how failure affects the rate of cesarean delivery.METHODS: We compared cesarean rates according to mode of onset of labor among 5,046 low-risk patients. Violation of the guidelines was defined as i... | ['Adult', 'Cesarean Section', 'Female', 'France', 'Gestational Age', 'Guideline Adherence', 'Humans', 'Labor, Induced', 'Logistic Models', 'Multivariate Analysis', 'Oxytocin', 'Parity', 'Pregnancy', 'Prospective Studies', 'Risk Factors'] | 17,520,395 | [['M01.060.116'], ['E04.520.252.500'], ['Z01.542.286'], ['G07.345.500.325.235.968', 'G08.686.320'], ['N04.761.337', 'N05.715.360.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.520.252.968'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A simple method to construct T-vectors using XcmI cassettes amplified by nonspecific PCR. | Polymerase chain reaction (PCR) is one of the most powerful tools in cloning genes. For the direct cloning of PCR products, T-vectors, which contain complementary 3'-thymidine overhangs, are widely used. In the present study, we developed a plasmid, pNB-T, which was constructed by cloning an XcmI cassette with a suffic... | ['Deoxyribonucleases, Type II Site-Specific', 'Gene Amplification', 'Genetic Vectors', 'Plasmids', 'Polymerase Chain Reaction'] | 11,319,930 | [['D08.811.150.280.260', 'D08.811.277.352.335.350.300.260', 'D08.811.277.352.355.325.300.260'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['G05.360.337'], ['G05.360.600'], ['E05.393.620.500']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Determination of organochlorine pesticide residues in soil/sediment using isotope dilution gas chromatography-mass spectrometry]. | A method was developed for the determination of organochlorine pesticide (OCP) residues in soil/sediment using high resolution gas chromatography coupled with low resolution mass spectrometry. The analytical procedures consisted of Soxhlet extraction, sulfur removal with copper powder, clean-up with gel permeation chro... | ['Gas Chromatography-Mass Spectrometry', 'Geologic Sediments', 'Hydrocarbons, Chlorinated', 'Pesticide Residues', 'Soil', 'Soil Pollutants'] | 20,812,624 | [['E05.196.181.349.500', 'E05.196.566.500'], ['G01.311.330', 'G16.500.320'], ['D02.455.526.439'], ['D27.720.031.700.672', 'D27.888.723.697', 'N06.850.460.200.700'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D27.888.284.756']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Anesthesia Exposure and Risk of Dementia and Alzheimer's Disease: A Prospective Study. | OBJECTIVES: To evaluate the associations between anesthesia and dementia or Alzheimer's disease (AD) risk using prospectively collected data.DESIGN: Cohort study.PARTICIPANTS: Community-dwelling members of the Adult Changes in Thought cohort aged 65 and older and free of dementia at baseline (N = 3,988).MEASUREMENTS: P... | ['Aged', 'Aged, 80 and over', 'Alzheimer Disease', 'Anesthesia, General', 'Anesthesia, Local', 'Dementia', 'Female', 'Humans', 'Male', 'Proportional Hazards Models', 'Prospective Studies', 'Risk Factors'] | 26,865,152 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E03.155.197'], ['E03.155.086.231'], ['C10.228.140.380', 'F03.615.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.700', 'E05.318.740.600.700', 'E05.318.740.750.725', 'E05.318.740.998.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Whole-Mount In Situ Hybridization in Zebrafish Embryos and Tube Formation Assay in iPSC-ECs to Study the Role of Endoglin in Vascular Development. | Vascular development is determined by the sequential expression of specific genes, which can be studied by performing in situ hybridization assays in zebrafish during different developmental stages. To investigate the role of endoglin(eng) in vessel formation during the development of hereditary hemorrhagic telangiecta... | ['Animals', 'Cardiovascular System', 'Endoglin', 'Endothelial Cells', 'Gene Knockdown Techniques', 'Humans', 'In Situ Hybridization', 'Induced Pluripotent Stem Cells', 'Mutation', 'Neural Tube', 'Protein Binding', 'Telangiectasia, Hereditary Hemorrhagic', 'Zebrafish'] | 32,538,908 | [['B01.050'], ['A07'], ['D12.776.543.750.250'], ['A11.436.275'], ['E05.393.335.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['A11.872.040.500', 'A11.872.700.500'], ['G05.36... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Infection Status with Metagonimus spp. Metacercariae in Fishes from Seomjin-gang and Tamjin-gang in Republic of Korea. | To grasp the infection status of Metagonimus spp. metacercariae (MsMc), the freshwater fishes were surveyed from Seomjin-gang (river) and Tamjin-gang in the Republic of Korea. Total 1,604 fishes from 7 local sites of Seomjin-gang and 1,649 fishes from 2 sites of Tamjin-gang were examined for 6 years (2012-2017) by the ... | ['Animals', 'Fish Diseases', 'Fishes', 'Fresh Water', 'Heterophyidae', 'Metacercariae', 'Prevalence', 'Republic of Korea', 'Trematode Infections'] | 30,196,667 | [['B01.050'], ['C22.362'], ['B01.050.150.900.493'], ['G16.500.275.280', 'N06.230.232'], ['B01.050.500.500.736.715.465'], ['B05.500.500.150.500', 'G07.345.500.550.500.500.150.500'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['Z01.252.474.557.750'], ... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Voluntary control of corticomuscular coherence through neurofeedback: a proof-of-principle study in healthy subjects. | Corticomuscular coherence (CMC) relates to synchronization between activity in the motor cortex and the muscle activity. The strength of CMC can be affected by motor behavior. In a proof-of-principle study, we examined whether independent of motor output parameters, healthy subjects are able to voluntarily modulate CMC... | ['Adult', 'Beta Rhythm', 'Electroencephalography', 'Electromyography', 'Female', 'Hand', 'Humans', 'Male', 'Motor Activity', 'Motor Cortex', 'Muscle, Skeletal', 'Neurofeedback', 'Volition'] | 25,596,321 | [['M01.060.116'], ['E01.370.376.300.150.750', 'E01.370.405.245.287.750', 'G07.265.087.750', 'G11.561.127.750'], ['E01.370.376.300', 'E01.370.405.245'], ['E01.370.405.255', 'E01.370.530.255'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.632', 'G11.427.410.698'], ['A08.186.211.200.885.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
(CT)n (GA)n repeats and heat shock elements have distinct roles in chromatin structure and transcriptional activation of the Drosophila hsp26 gene. | Previous analysis of the hsp26 gene of Drosophila melanogaster has shown that in addition to the TATA box and the proximal and distal heat shock elements (HSEs) (centered at -59 and -340, relative to the start site of transcription), a segment of (CT)n repeats at -135 to -85 is required for full heat shock inducibility... | ['Animals', 'Base Sequence', 'Binding Sites', 'Chromatin', 'Cytosine', 'DNA-Binding Proteins', 'Deoxyribonuclease I', 'Drosophila melanogaster', 'Gene Expression', 'Gene Expression Regulation', 'Heat-Shock Proteins', 'Hot Temperature', 'Molecular Sequence Data', 'Oligodeoxyribonucleotides', 'Plasmids', 'Repetitive Sequ... | 8,474,442 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D03.383.742.698.421'], ['D12.776.260'], ['D08.811.277.352.335.350.250'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G05.297'], ['G05.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Testicular cavernous hemangioma presenting as an ipsilateral lesion in a child with multicystic dysplastic kidney. | Childhood malignant testicle tumors are very rare. In the literature to date, it has been reported that there are only 24 cavernous hemangioma cases existing in English literature. In this study, we discuss a testicular mass case which was diagnosed as cavernous hemangioma. The patient, who followed for left multicysti... | ['Hemangioma, Cavernous', 'Humans', 'Infant', 'Male', 'Multicystic Dysplastic Kidney', 'Testicular Neoplasms', 'Testis'] | 27,735,807 | [['C04.557.645.375.385', 'C14.907.454.385', 'C15.378.463.515.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C12.706.629', 'C12.777.419.403.750', 'C13.351.875.558', 'C13.351.968.419.403.750', 'C16.131.939.629'], ['C04.588.322.762', 'C04.588.945.440.915', 'C12.294.260.937', 'C12.758.409.937', ... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The hair of the common hare (Lepus europaeus Pall.) and of the common vole (Microtus arvalis Pall.) as indicator of the environmental pollution. | We made the INAA of hair of the common hare (Lepus europaeus Pall.) and of the common vole (Microtus arvalis Pall.) living in the emission zones. Both the hare and the vole are almost exclusively herbivores; they consume relatively large amounts of contaminated food and mirror reliably the contamination degree of the r... | ['Animals', 'Arvicolinae', 'Czechoslovakia', 'Environmental Monitoring', 'Hair', 'Lagomorpha', 'Neutron Activation Analysis', 'Trace Elements'] | 3,517,159 | [['B01.050'], ['B01.050.150.900.649.313.992.635.075'], ['Z01.586.250'], ['N06.850.460.350.080', 'N06.850.780.375'], ['A17.360'], ['B01.050.150.900.649.313.968'], ['E05.196.039.564'], ['D01.268.811', 'D27.505.696.494.555', 'G07.203.300.681.500.555', 'J02.500.681.500.555']] | ['Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Translational selection is ubiquitous in prokaryotes. | Codon usage bias in prokaryotic genomes is largely a consequence of background substitution patterns in DNA, but highly expressed genes may show a preference towards codons that enable more efficient and/or accurate translation. We introduce a novel approach based on supervised machine learning that detects effects of ... | ['Archaea', 'Bacteria', 'Codon', 'Gene Expression Regulation', 'Genome', 'Models, Genetic', 'Prokaryotic Cells', 'Protein Biosynthesis', 'Ribosomal Proteins'] | 20,585,573 | [['B02'], ['B03'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['G05.308'], ['G05.360.340'], ['E05.599.395.397'], ['A11.760'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['D12.776.835']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of inspiratory muscle training with load compared with sham training on blood pressure in individuals with hypertension: study protocol of a double-blind randomized clinical trial. | BACKGROUND: Hypertension is a complex chronic condition characterized by elevated arterial blood pressure. Management of hypertension includes non-pharmacologic strategies, which may include techniques that effectively reduce autonomic sympathetic activity. Respiratory exercises improve autonomic control over cardiovas... | ['Adult', 'Blood Pressure', 'Blood Pressure Monitoring, Ambulatory', 'Breathing Exercises', 'Clinical Protocols', 'Double-Blind Method', 'Essential Hypertension', 'Female', 'Humans', 'Inhalation', 'Male', 'Middle Aged', 'Portugal', 'Research Design', 'Respiratory Muscles', 'Sympathetic Nervous System', 'Time Factors', ... | 27,484,507 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140.100', 'E01.370.520.500.100'], ['E02.190.525.186', 'E02.779.474.124'], ['E02.183', 'N05.715.360.330.125'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C14.907.489.165'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
The Health Legislation Amendment Act 2013 (QLD) and Queensland's health assets privatisation dispute. | 'New legislation in Queensland has provided a "pathway" for the privatisation of health assets and services in Queensland, which effectively realigns the health care system to the financial market. This column explores how this legislation contained the antecedents of the Queensland doctors' dispute when doctors roundl... | ['Contracts', 'Employment', 'Humans', 'National Health Programs', 'Physicians', 'Privatization', 'Queensland'] | 25,341,319 | [['I01.880.604.583.090', 'N03.706.535.241'], ['N01.824.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.349.550'], ['M01.526.485.810', 'N02.360.810'], ['N04.452.633.780'], ['Z01.639.100.937', 'Z01.678.100.373.937']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Speckle-tracking imaging in patients with Eisenmenger syndrome. | BACKGROUND: Adults with Eisenmenger syndrome have a survival advantage over those with idiopathic pulmonary arterial hypertension. Improved survival may result from preservation of right ventricular (RV) function.AIMS: To assess left ventricular (LV) and RV remodelling in patients with Eisenmenger syndrome compared to ... | ['Adult', 'Biomechanical Phenomena', 'Case-Control Studies', 'Echocardiography, Doppler', 'Eisenmenger Complex', 'Female', 'France', 'Humans', 'Hypertension, Pulmonary', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Prognosis', 'Prospective Studies', 'Stress, Mechanical', 'Ventricular Function, Left', 'Ventricul... | 26,868,160 | [['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['C14.240.400.450', 'C14.280.400.450', 'C16.131.240.400.450'], ['Z01.542.286'], [... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Piezoelectric allostery of protein. | Allostery is indispensable for a protein to work, where a locally applied stimulus is transmitted to a distant part of the molecule. While the allostery due to chemical stimuli such as ligand binding has long been studied, the growing interest in mechanobiology prompts the study of the mechanically stimulated allostery... | ['Allosteric Regulation', 'Models, Molecular', 'Molecular Dynamics Simulation', 'Protein Conformation', 'Proteins', 'Static Electricity'] | 27,575,163 | [['G02.111.044'], ['E05.599.595'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['G02.111.570.820.709'], ['D12.776'], ['G01.358.500.249.820']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Role of periostin in cancer progression and metastasis: inhibition of breast cancer progression and metastasis by anti-periostin antibody in a murine model. | Periostin (PN), a secreted adhesion-related protein expressed in the periosteum and periodontal ligaments, acts as a critical regulator of the formation and maintenance of bone and teeth, and also plays an important role in tumorigenesis. Although PN is highly expressed in various types of human cancers, its function i... | ['Animals', 'Antibodies', 'Bone and Bones', 'Breast Neoplasms', 'Cell Adhesion Molecules', 'Cell Death', 'Cell Differentiation', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Disease Progression', 'Female', 'Gene Expression Regulation, Neoplastic', 'Mice', 'Mice, Inbred BALB C', 'Neoplasm Metastasis', 'Os... | 21,617,848 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['A02.835.232', 'A10.165.265'], ['C04.588.180', 'C17.800.090.500'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['G04.146'], ['G04.152'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Reversible Hydride Transfer to N,N'-Diarylimidazolinium Cations from Hydrogen Catalyzed by Transition Metal Complexes Mimicking the Reaction of [Fe]-Hydrogenase. | [Fe]-hydrogenase is a key enzyme involved in methanogenesis and facilitates reversible hydride transfer from H2 to N5,N10-methenyltetrahydromethanopterin (CH-H4MPT+). In this study, a reaction system was developed to model the enzymatic function of [Fe]-hydrogenase by using N,N'-diphenylimidazolinium cation (1+) as a s... | ['Biomimetic Materials', 'Catalysis', 'Cations', 'Coordination Complexes', 'Hydrogen', 'Hydrogenase', 'Imidazolidines', 'Iron-Sulfur Proteins', 'Models, Chemical', 'Protons', 'Solvents', 'Transition Elements'] | 28,654,277 | [['J01.637.087'], ['G02.130'], ['D01.248.497.300'], ['D01.234', 'D02.257'], ['D01.268.406', 'D01.362.340'], ['D08.811.682.400'], ['D03.383.129.308.432'], ['D12.776.157.427.374.375', 'D12.776.556.579.374.375'], ['E05.599.495'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['D27.7... | ['Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
LC-ESI-MS analysis of taxoids from the bark of Taxus wallichiana. | LC-ESI-MS analysis was carried out for taxoid profiling of partially purified methanol extracts of the stem bark of Taxus wallichiana growing in different regions of the Himalayas (Kashmir, Himachal Pradesh, UP hills, Sikkim and Arunachal Pradesh). Cone voltage fragmentation of the protonated, ammonium or sodium cation... | ['Alkaloids', 'Chromatography, Liquid', 'Spectrometry, Mass, Electrospray Ionization', 'Taxus'] | 12,210,508 | [['D03.132'], ['E05.196.181.400'], ['E05.196.566.600'], ['B01.650.940.800.575.912.625.937.500']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition of cisplatin-induced emesis in the pigeon by a non-psychotropic synthetic cannabinoid. | The (+) enantiomer of the synthetic cannabinoid, 7-hydroxy-delta-6-tetrahydrocannabinol, dimethylheptyl homolog (HU-211), possesses significant antimetic efficacy in the pigeon. However, unlike all anti-emetic cannabinoids tested in the past, it is devoid of psychotropic (cannabimimetic) activity. The anti-emetic activ... | ['Animals', 'Antiemetics', 'Cannabinoids', 'Cisplatin', 'Columbidae', 'Copper', 'Dronabinol', 'Female', 'Male', 'Vomiting'] | 2,557,222 | [['B01.050'], ['D27.505.696.663.050.030', 'D27.505.954.427.095', 'D27.505.954.483.200'], ['D02.455.849.090'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['B01.050.150.900.248.165.150'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D02.455.849.090.810'], ['C23.888.821.937']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prolactin release induced by physical exercise is independent from peripheral vasoactive intestinal polypeptide secretion. | The plasma concentrations of vasoactive intestinal polypeptide and prolactin were measured before and after an exhaustive and a submaximal exercise test in 7 male marathon runners. A significant increase of vasoactive intestinal polypeptide was recorded after both tests, whereas the prolactin increase was observed only... | ['Adult', 'Exercise', 'Humans', 'Male', 'Prolactin', 'Vasoactive Intestinal Peptide'] | 3,218,916 | [['M01.060.116'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.322.576.773', 'D06.472.699.631.525.525', 'D12.644.548.691.525.525'], ['D06.472.317.950', 'D06.472.699.952', 'D12.644.400.875', 'D12.644.548.952', 'D12.776.631.650.875']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Limits to exercise performance: some ideas from comparative studies. | Examples of exercise performance and metabolic scope in non-human mammalian species are considered from the point of view of problems and questions which may provide insights into evolutionary processes influencing adaptations to muscular activity. Consideration of both aerobic and anaerobic performance is required. So... | ['Aerobiosis', 'Anaerobiosis', 'Animals', 'Caniformia', 'Diving', 'Horses', 'Mitochondria, Heart', 'Muscle Proteins', 'Oxygen Consumption', 'Physical Exertion', 'Seals, Earless', 'Species Specificity'] | 3,471,056 | [['G02.111.017', 'G03.049'], ['G02.111.062', 'G03.078'], ['B01.050'], ['B01.050.150.900.649.313.750.250'], ['I03.450.642.845.945.500.110', 'N06.230.150.150'], ['B01.050.150.900.649.313.984.235.472'], ['A11.284.430.214.190.875.564.627.603', 'A11.284.835.626.627.603'], ['D12.776.210.500'], ['G03.680'], ['G11.427.683'], [... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Changes in renal function after implantation of continuous-flow left ventricular assist devices. | OBJECTIVES: The aim of this study was to determine renal outcomes after left ventricular assist device (LVAD) implantation.BACKGROUND: Renal dysfunction before LVAD placement is frequent, and it is unclear whether it is due to primary renal disease or to poor perfusion.METHODS: A retrospective single-center analysis wa... | ['Aged', 'Cohort Studies', 'Confidence Intervals', 'Female', 'Follow-Up Studies', 'Glomerular Filtration Rate', 'Heart Failure', 'Heart-Assist Devices', 'Humans', 'Kidney Function Tests', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Postoperative Care', 'Predictive Value of Tests', 'Preoperative Care', 'Renal Insuf... | 22,192,665 | [['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.390.400.300', 'G08.852.357'], ['C14.280.434'], ['E0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Myocarditis: magnetic resonance imaging diagnosis and follow-up]. | Myocarditis, inflammation of the myocardium, is usually due to viral infection. Diagnostic confirmation in ordinary clinical practice is difficult because the findings on the clinical history, physical examination, electrocardiogram, and laboratory tests offer scant diagnostic accuracy, and the differential diagnosis i... | ['Adult', 'Follow-Up Studies', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Myocarditis', 'Prognosis', 'Young Adult'] | 23,098,997 | [['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C14.280.238.625'], ['E01.789'], ['M01.060.116.815']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Phase II study of fenretinide (N-[4-hydroxyphenyl]retinamide) in advanced breast cancer and melanoma. | Retinoids, the natural and synthetic analogs of vitamin A, are growth-inhibiting and differentiation-inducing agents and show clinical promise as chemopreventive and antineoplastic agents. Fenretinide, a new synthetic retinoid, has antitumor activity in certain in vitro and in vivo model systems and was relatively nont... | ['Adult', 'Aged', 'Breast Neoplasms', 'Drug Evaluation', 'Female', 'Fenretinide', 'Humans', 'Male', 'Melanoma', 'Middle Aged', 'Tretinoin'] | 2,148,744 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['E05.290.625', 'E05.337.425'], ['D02.455.326.271.665.202.495.270', 'D02.455.426.392.368.367.379.249.700.270', 'D02.455.849.131.495.270', 'D23.767.261.700.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.510', 'C04.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sex differences in hemodynamic responses and long-term survival to optimal medical therapy in patients with pulmonary arterial hypertension. | It is widely known that the incidence of pulmonary arterial hypertension (PAH) is higher in female, whereas prognosis is poorer in male patients. However, sex differences in hemodynamic response to and long-term prognosis with PAH-targeted treatment in the modern era remain to be fully elucidated. We examined the long-... | ['Adult', 'Antihypertensive Agents', 'Female', 'Follow-Up Studies', 'Hemodynamics', 'Humans', 'Hypertension, Pulmonary', 'Japan', 'Male', 'Middle Aged', 'Prognosis', 'Pulmonary Artery', 'Retrospective Studies', 'Risk Assessment', 'Sex Distribution', 'Sex Factors', 'Survival Rate', 'Time Factors'] | 29,441,403 | [['M01.060.116'], ['D27.505.954.411.162'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['E01.789'], ['A07.015.114.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Pneumomediastinum following a prolonged second stage of labor - an emphasis on early diagnosis and conservative management: a case report. | BACKGROUND: Esophageal rupture is an extremely rare condition to occur to a pregnant or postnatal woman. Esophageal ruptures have been previously described in the literature; however, they are most common in the setting of hyperemesis gravidarum.CASE PRESENTATION: This case report describes a 27-year-old white woman wh... | ['Adult', 'Angiography', 'Chest Pain', 'Conservative Treatment', 'Early Diagnosis', 'Esophageal Perforation', 'Female', 'Humans', 'Labor, Obstetric', 'Mediastinal Emphysema', 'Postpartum Period', 'Pregnancy', 'Radiography, Thoracic', 'Tomography, X-Ray Computed', 'Treatment Outcome'] | 29,110,705 | [['M01.060.116'], ['E01.370.350.700.060', 'E01.370.370.050'], ['C23.888.592.612.233'], ['E02.197'], ['E01.390'], ['C06.405.117.468', 'C26.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769.326'], ['C08.846.187.290', 'C23.550.325.250'], ['G08.686.702'], ['G08.686.784.769'], ['E01.370.350.700.730']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Driver Gaze Behavior Is Different in Normal Curve Driving and when Looking at the Tangent Point. | Several steering models in the visual science literature attempt to capture the visual strategies in curve driving. Some of them are based on steering points on the future path (FP), others on tangent points (TP). It is, however, challenging to differentiate between the models' predictions in real-world contexts. Analy... | ['Adult', 'Automobile Driving', 'Female', 'Fixation, Ocular', 'Humans', 'Male', 'Middle Aged', 'Motion Perception', 'Nystagmus, Optokinetic', 'Psychomotor Performance', 'Vision, Ocular', 'Young Adult'] | 26,287,914 | [['M01.060.116'], ['I03.125'], ['G14.350.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F02.463.593.932.567'], ['G14.350.378.500'], ['F02.808', 'G11.427.700', 'G11.561.660'], ['F02.830.816.964', 'G02.111.820.480.900', 'G04.835.480.900', 'G11.561.790.964', 'G14.935'], ['M01.060.116.815']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
How Has the Lower Boundary of Human Mortality Evolved, and Has It Already Stopped Decreasing? | In contrast to the upper boundary of mortality, the lower boundary has so far largely been neglected. Based on the three key features-location, sex-specific difference, and level-I analyze past and present trends in the lower boundary of human mortality. The analysis is based on cohort mortality data for 38 countries, ... | ['Age Factors', 'Cohort Studies', 'Humans', 'Models, Statistical', 'Mortality', 'Residence Characteristics', 'Sex Factors'] | 30,076,587 | [['N05.715.350.075', 'N06.850.490.250'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.550',... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Clinical Factors Predicting Tumour Upgrading in Patients Under Active Surveillance and Elected to Active Treatment after Disease Reclassification or Progression. | OBJECTIVES: To evaluate clinical factors associated with tumour upgrading (UPG) in low-intermediate risk patients who progressed while under active surveillance (AS) and underwent delayed radical prostatectomy.MATERIAL AND METHODS: The evaluated factors included prostate specific antigen (PSA), prostate volume, PSA den... | ['Aged', 'Biopsy', 'Chi-Square Distribution', 'Disease Progression', 'Humans', 'Kallikreins', 'Logistic Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Grading', 'Odds Ratio', 'Predictive Value of Tests', 'Prostate-Specific Antigen', 'Prostatectomy', 'Prostatic Neoplasms', 'Retrospective Studies', 'R... | 28,196,367 | [['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.40... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Oncology nurses' experiences with requests for assisted dying from terminally ill patients with cancer. | PURPOSE/OBJECTIVES: To explore oncology nurses' experiences with receiving requests for assisted dying from terminally ill patients with cancer.DESIGN: Descriptive, naturalistic.SETTING: RNs who identified themselves as direct care providers or clinical nurse specialist members of the Oncology Nursing Society.SAMPLE: 4... | ['Adult', 'Analgesics, Opioid', 'Attitude of Health Personnel', 'Communication', 'Conflict, Psychological', 'Data Collection', 'Ethics, Nursing', 'Female', 'Humans', 'Internal-External Control', 'Male', 'Middle Aged', 'Morphine', 'Neoplasms', 'Nurse-Patient Relations', 'Suicide, Assisted', 'Terminal Care', 'United Stat... | 11,198,896 | [['M01.060.116'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['F01.100.050', 'N05.300.100'], ['F01.145.209', 'L01.143'], ['F01.658.209'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['K01.752.566.479.171.132.875... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geogr... | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
R-(+)-verapamil, S-(-)-verapamil, and racemic verapamil inhibit human retinal pigment epithelial cell contraction. | PURPOSE: To evaluate the effects of R-(+)-verapamil, S-(-)-verapamil, and the racemate on in vitro contraction of human retinal pigment epithelial cells.METHODS: RPE cells from human donor eyes were enzymatically dissociated and cultured on collagen gels. Transdifferentiated RPE cells (seventh and eighth passage) were ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Calcium Channel Blockers', 'Cell Division', 'Cells, Cultured', 'Collagen', 'Dose-Response Relationship, Drug', 'Female', 'Gels', 'Humans', 'Male', 'Middle Aged', 'Pigment Epithelium of Eye', 'Stereoisomerism', 'Verapamil'] | 10,943,681 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G07.690.773.875', 'G07.690.936.500'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Evidence supporting a role of serotonin in modulation of sudden death induced by seizures in DBA/2 mice. | PURPOSE: Sudden unexpected death in epilepsy (SUDEP) is a serious concern for epilepsy patients. DBA/2 mice are proposed as a SUDEP model, because these mice exhibit respiratory arrest (RA) after audiogenic seizures (AGSs), and RA is also implicated in human SUDEP. Respiratory mechanisms are modulated, in part, by sero... | ['Animals', 'Cyproheptadine', 'Death, Sudden', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Epilepsy, Reflex', 'Fluoxetine', 'Genetic Predisposition to Disease', 'Humans', 'Mice', 'Mice, Inbred DBA', 'Respiratory Paralysis', 'Serotonin', 'Serotonin Agents', 'Serotonin Antagonists', 'Serotonin Uptake I... | 16,417,527 | [['B01.050'], ['D02.455.426.559.847.181.384.340', 'D03.383.621.160', 'D04.615.181.384.340'], ['C23.550.260.322'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.875', 'G07.690.936.500'], ['C10.228.140.490.450'], ['D02.092.831.280'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sentinel node mapping guided by indocyanine green fluorescence imaging: a new method for sentinel node navigation surgery in gastrointestinal cancer. | BACKGROUND: Recently, gastrointestinal cancer has also been identified as a target for sentinel node navigation surgery (SNNS). This study is the first to determine the feasibility of sentinel node (SN) mapping guided by indocyanine green (ICG) fluorescence imaging in gastrointestinal cancer.METHODS: Our series consist... | ['Aged', 'Colorectal Neoplasms', 'Coloring Agents', 'Female', 'Fluorescent Dyes', 'Humans', 'Indocyanine Green', 'Lymph Nodes', 'Male', 'Spectrophotometry, Infrared', 'Stomach Neoplasms'] | 18,379,188 | [['M01.060.116.100'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['D27.720.233'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.400'], ['A10.549.400',... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[TUBERCULOSIS ANNUAL REPORT 2014--(2) Tuberculosis in Pediatric and Elderly Patients]. | In 2014, 49 pediatric tuberculosis (TB) patients aged 0-14 years were newly notified in Japan, with a notification rate of 0.30 per 100,000 population. Since 2006, the number of pediatric TB patients notified each year has been less than 100. Of the 49 patients, 17 (34.7%) were aged 0-4 years, 15 (30.6%) were 5-9 years... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Humans', 'Infant', 'Infant, Newborn', 'Japan', 'Middle Aged', 'Tuberculosis, Pulmonary', 'Young Adult'] | 27,530,022 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Proximal duodenoileal anastomosis for treatment of small intestinal obstruction and volvulus in a green iguana (Iguana iguana). | CASE DESCRIPTION A 13-year-old female green iguana (Iguana iguana) was examined because of a 6-day history of vomiting, anorexia, and lethargy and a 4-day history of decreased fecal and urate output. CLINICAL FINDINGS Physical examination revealed a distended abdomen, signs of depression, pallor, tachycardia, harsh lun... | ['Anastomosis, Surgical', 'Animals', 'Duodenum', 'Female', 'Ileum', 'Intestinal Obstruction', 'Intestinal Volvulus', 'Lizards'] | 27,767,426 | [['E04.035'], ['B01.050'], ['A03.556.124.684.124', 'A03.556.875.249'], ['A03.556.124.684.249', 'A03.556.249.124'], ['C06.405.469.531'], ['C06.405.469.531.568', 'C23.300.970.500'], ['B01.050.150.900.833.393']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human papillomavirus type 16 virus-like particles expressed in attenuated Salmonella typhimurium elicit mucosal and systemic neutralizing antibodies in mice. | Attenuated strains of Salmonella are attractive live vaccine candidates for eliciting mucosal as well as systemic immune responses. The ability to induce immune responses in the reproductive tract may be critical for the effectiveness of a prophylactic vaccine against genital human papillomaviruses (HPV), which are imp... | ['Animals', 'Antibodies, Viral', 'Epitopes', 'Female', 'Genital Diseases, Female', 'Immune Sera', 'Immunity, Mucosal', 'Immunization', 'Mice', 'Mice, Inbred BALB C', 'Papillomaviridae', 'Papillomavirus Infections', 'Plasmids', 'Salmonella typhimurium', 'Tumor Virus Infections', 'Vaccines, Attenuated', 'Vaccines, Synthe... | 9,234,794 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D23.050.550'], ['C13.351.500'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.114.573', 'D20.215.401'], ['G12.450.573'], ['E02.095.465.425.400', 'E0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Role of phosphoinositide 3-kinase p110 delta in TLR4- and TLR9-mediated B cell cytokine production and differentiation. | Phosphoinositide 3-kinase (PI3K) enzymes play key roles in signaling via antigen receptors and cytokine receptors and isoform-selective PI3K inhibitors are being evaluated as targets for treatment of allergic and inflammatory diseases. The specific roles of PI3K isoforms in TLR-mediated activation of lymphocytes have n... | ['Animals', 'B-Lymphocytes', 'Cell Differentiation', 'Cell Proliferation', 'Class I Phosphatidylinositol 3-Kinases', 'Cytokines', 'Immunoglobulin Class Switching', 'Interleukin-10', 'Interleukin-6', 'Lipopolysaccharides', 'Mice', 'Mice, Inbred C57BL', 'Oligodeoxyribonucleotides', 'Phosphatidylinositol 3-Kinases', 'Phos... | 19,362,372 | [['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['D08.811.913.696.620.500.100.100', 'D08.811.913.696.620.500.200.100', 'D12.776.476.162'], ['D12.644.276.374', 'D12.776.467.374', 'D... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protective effect of Teucrium polium on carbon tetrachloride induced genotoxicity and oxidative stress in rats. | This study aimed to investigate the protective effects of Teucrium polium (TP) on carbon tetrachloride (CCl4) induced spleen, erythrocyte's oxidative stress, and genotoxicity in rats. TP was found to contain large amounts of polyphenols (150 mg GAE/G of dry plant) and flavonoids (60 mg QE/g of quercetin dry plant). The... | ['Animals', 'Antioxidants', 'Carbon Tetrachloride Poisoning', 'Chromosome Aberrations', 'DNA Damage', 'Erythrocytes', 'Ethnopharmacology', 'Flavonoids', 'Lipid Peroxidation', 'Male', 'Medicine, African Traditional', 'Necrosis', 'Oxidative Stress', 'Plant Components, Aerial', 'Plant Extracts', 'Protective Agents', 'Rand... | 28,714,319 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C25.723.177'], ['C23.550.210', 'G05.365.590.175'], ['G05.200'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['H01.158.703.015', 'H02.628.100', 'I01.076.201.450.654.252'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['G02.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Tissue-specific expression and dietary regulation of chimeric mitochondrial 3-hydroxy-3-methylglutaryl coenzyme A synthase/human growth hormone gene in transgenic mice. | We have studied the role of the mitochondrial 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) synthase gene in regulating ketogenesis. The gene exhibits expression in various tissues and it is regulated in a tissue-specific manner. To investigate the underlying mechanisms of this expression, we linked a 1148-base-pair portion... | ['Animals', 'Base Composition', 'Base Sequence', 'DNA Primers', 'Diet', 'Fasting', 'Female', 'Gene Expression Regulation', 'Genes', 'Growth Hormone', 'Humans', 'Hydroxymethylglutaryl-CoA Synthase', 'Infant, Newborn', 'Ketone Bodies', 'Liver', 'Male', 'Mice', 'Mice, Inbred Strains', 'Mice, Transgenic', 'Mitochondria', '... | 8,631,784 | [['B01.050'], ['G02.111.080'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G07.203.650.240'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['G05.308'], ['G05.360.340.024.340'], ['D06.472.699.631.525.425', 'D12.644.548.691... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
A simple model for teaching postmortem monocular indirect ophthalmoscopy. | Although the ophthalmoscope was invented by Hermann von Helmholtz in 1851, pathologists until recently have relied almost exclusively on ocular enucleation to identify and describe postmortem fundal abnormalities. An inexpensive but valuable tool for forensic pathologists, the postmortem monocular indirect ophthalmosco... | ['Forensic Pathology', 'Fundus Oculi', 'Humans', 'Internship and Residency', 'Models, Structural', 'Ophthalmology', 'Ophthalmoscopes', 'Ophthalmoscopy', 'Retinal Hemorrhage'] | 19,432,744 | [['H02.403.330.300', 'H02.403.650.249', 'I01.198.780.937.460'], ['A09.371.729.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['J01.897.280.500.545', 'L01.178.820.090.545'], ['H02.403.810.468'], ['E07.230.540'], ['E01.370.380.560'], ['C11.290.807', 'C11.768.710', ... | ['Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 |
Response to lysophosphatidic acid in Xenopus oocytes and its rapid desensitization: the role of Gq and Go G-protein families. | Native Xenopus oocytes exhibit dose-dependent depolarizing current responses to lysophosphatidic acid (LPA), with EC50 = 0.18 microM. Responses to LPA were subject to pronounced rapid desensitization. When oocytes were challenged with 5 nM LPA, the response was <10% of the maximal. Subsequent addition of 0.5 microM LPA... | ['Animals', 'Blotting, Western', 'Dose-Response Relationship, Drug', 'Female', 'GTP-Binding Protein alpha Subunits, Gi-Go', 'GTP-Binding Protein alpha Subunits, Gq-G11', 'Heterotrimeric GTP-Binding Proteins', 'Lysophospholipids', 'Membrane Potentials', 'Microinjections', 'Oligonucleotides, Antisense', 'Oocytes', 'Pertu... | 15,137,065 | [['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G07.690.773.875', 'G07.690.936.500'], ['D08.811.277.040.330.300.200.100.200', 'D12.644.360.360.100.200', 'D12.776.157.325.332.100.200', 'D12.776.476.375.100.200', 'D12.776.543.325.100.200'], ['D08.811.27... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Radiation-induced skull base leiomyosarcoma presenting with intracerebral haemorrhage. | Radiation-induced neoplasm including meningioma, glioma and sarcoma, is an uncommon but known consequence after therapeutic irradiation of pituitary tumour. Radiation-induced leiomyosarcoma due to previous sellar irradiation has only been reported once in the literature. We herein present the second case of radiation-i... | ['Adenoma', 'Adult', 'Cerebral Hemorrhage', 'Fatal Outcome', 'Female', 'Humans', 'Leiomyosarcoma', 'Neoplasms, Radiation-Induced', 'Pituitary Neoplasms', 'Skull Base Neoplasms', 'Tomography, X-Ray'] | 17,928,491 | [['C04.557.470.035'], ['M01.060.116'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.590.455', 'C04.557.450.795.45... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A Risk-prediction Model Based on Lymph-node Metastasis for Incorporation Into a Treatment Algorithm for Signet Ring Cell-type Intramucosal Gastric Cancer. | OBJECTIVE: The aim of the study was to develop a reliable and easy-to-use risk-scoring system (RSS) to predict lymph-node metastasis (LNM) and determine the feasibility of endoscopic submucosal dissection for mucosa-confined signet ring cell carcinomas (SRCs).BACKGROUND: Fewer LNM and better survival rates have been re... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Signet Ring Cell', 'Female', 'Gastrectomy', 'Gastric Mucosa', 'Gastroscopy', 'Humans', 'Incidence', 'Lymph Node Excision', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Grading', 'Neoplasm Staging', 'Predictive Value of Tests', 'Prospective Studies', 'Risk A... | 27,828,821 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.025.415', 'C04.557.470.590.415'], ['E04.210.419'], ['A03.556.875.875.440', 'A10.615.550.291'], ['E01.370.372.250.250.325', 'E01.370.388.250.250.250.320', 'E04.210.240.250.320', 'E04.502.250.250.250.320'], ['B01.050.150.900.649.313.988.400... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
High-resolution photoelectron spectra of the pyrimidine-type nucleobases. | High-resolution photoelectron spectra of the gas phase pyrimidine-type nucleobases, thymine, uracil, and cytosine, were collected using synchrotron radiation over the photon energy range 17 ? hí ? 150 eV. These data provide the highest resolution photoelectron spectra of thymine, uracil, and cytosine published to date.... | ['Cytosine', 'Electrons', 'Gases', 'Ions', 'Photochemistry', 'Photons', 'Pyrimidines', 'Thymine', 'Uracil'] | 26,071,713 | [['D03.383.742.698.421'], ['G01.249.335', 'G01.358.500.750'], ['D01.362'], ['D01.248.497'], ['H01.181.529.711'], ['G01.249.705', 'G01.358.500.505.650.782', 'G01.590.540.782', 'G01.750.250.650.782', 'G01.750.770.578.782'], ['D03.383.742'], ['D03.383.742.698.875.899'], ['D03.383.742.698.875']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Paratesticular m?llerian-type papillary serous tumor in a child. | We describe a case of a 15-year-old male presenting with an unusual right-sided paratesticular mass in whom the diagnosis of an ovarian-like paratesticular m?llerian-type papillary serous tumor was made. The tumor, also referred to as serous papillary cystadenoma by some authors, depicted papillae with fibro-vascular c... | ['Adolescent', 'Biomarkers, Tumor', 'Cystadenocarcinoma, Papillary', 'Cystadenocarcinoma, Serous', 'Humans', 'Immunohistochemistry', 'Male', 'Testicular Neoplasms'] | 19,348,511 | [['M01.060.057'], ['D23.101.140'], ['C04.557.470.200.025.480.230', 'C04.557.470.590.480.230'], ['C04.557.470.200.025.480.240', 'C04.557.470.590.480.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
The Dok-3/Grb2 protein signal module attenuates Lyn kinase-dependent activation of Syk kinase in B cell antigen receptor microclusters. | Recruitment of the growth factor receptor-bound protein 2 (Grb2) by the plasma membrane-associated adapter protein downstream of kinase 3 (Dok-3) attenuates signals transduced by the B cell antigen receptor (BCR). Here we describe molecular details of Dok-3/Grb2 signal integration and function, showing that the Lyn-dep... | ['Adaptor Proteins, Signal Transducing', 'Amino Acids', 'Animals', 'Calcium', 'Calcium Signaling', 'Chickens', 'Enzyme Activation', 'GRB2 Adaptor Protein', 'Humans', 'Lymphocyte Activation', 'Mass Spectrometry', 'Microscopy, Confocal', 'Receptors, Antigen, B-Cell', 'Signal Transduction', 'src-Family Kinases'] | 23,223,229 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['D12.125'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G02.111.263', 'G03.328'], ['D12.644.360.024.290', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A reproductive and developmental screening study of the fungal toxin ochratoxin A in Fischer rats. | The presence of the mycotoxin ochratoxin A (OTA) in cereal grains is due to the growth of toxigenic Penicillium mold on stored crops. Human exposure to OTA is higher in infants, toddlers, and children than in adolescents and adults, based on exposure assessments of ng OTA consumed/kg body weight/day. Ochratoxin A is ne... | ['Abnormalities, Drug-Induced', 'Administration, Oral', 'Animals', 'Disease Models, Animal', 'Female', 'Ochratoxins', 'Poisoning', 'Pregnancy', 'Pregnancy Complications', 'Rats, Inbred F344', 'Renal Insufficiency', 'Teratogens'] | 29,971,579 | [['C16.131.042'], ['E02.319.267.100'], ['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D03.383.663.283.446.800.500', 'D03.633.100.150.446.800.500', 'D23.946.587.697'], ['C25.723'], ['G08.686.784.769'], ['C13.703'], ['B01.050.050.199.520.760.200', 'B01.050.150.900.649.313.992.635.505.700.400.200'], ['C12.7... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Curriculum for an Interprofessional Seminar on Integrated Primary Care: Developing Competencies for Interprofessional Collaborative Practice. | Health care is increasingly delivered through team-based, collaborative strategies with interprofessional education as an important mechanism for building interprofessional practice competencies. This paper describes an Interprofessional Seminar on Integrated Primary Care (IS-IPC) designed to meet this educational need... | ['Allied Health Occupations', 'Cooperative Behavior', 'Curriculum', 'Health Policy', 'Humans', 'Interprofessional Relations', 'Leadership', 'Patient Care Team', 'Primary Health Care', 'Problem-Based Learning', 'Quality Improvement'] | 30,194,832 | [['H02.010'], ['F01.145.813.115'], ['I02.158'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205'], ['F01.752.609'], ['N04.590.715'], ['N04.590.233.727'], ['F02.463.425.720', 'I02.158.660', 'I02.903.565'], ['J01.293.754', 'N04.... | ['Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 |
Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes. | HAPLESS2 (HAP2) is a broadly conserved, gamete-expressed transmembrane protein that was shown recently to be structurally homologous to viral class II fusion proteins, which initiate fusion with host cells via insertion of fusion loops into the host membrane. However, the functional conformation of the HAP2 fusion loop... | ['Arabidopsis', 'Arabidopsis Proteins', 'Biological Evolution', 'Carrier Proteins', 'Chlamydomonas', 'Eukaryota', 'Genetic Variation', 'Germ Cells', 'Membrane Fusion', 'Sequence Homology, Amino Acid'] | 30,102,690 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G05.045', 'G16.075'], ['D12.776.157'], ['B01.650.940.150.385'], ['B01'], ['G05.365'], ['A05.360.490', 'A11.497'], ['G04.575'], ['G02.111.810.200', 'G05.810.200']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
STAT3-regulated exosomal miR-21 promotes angiogenesis and is involved in neoplastic processes of transformed human bronchial epithelial cells. | Although microRNA (miRNA) enclosed in exosomes can mediate intercellular communication, the roles of exosomal miRNA and angiogenesis in lung cancer remain unclear. We investigated functions of STAT3-regulated exosomal miR-21 derived from cigarette smoke extract (CSE)-transformed human bronchial epithelial (HBE) cells i... | ['Cell Transformation, Neoplastic', 'Cells, Cultured', 'Epithelial Cells', 'Exosomes', 'Humans', 'Lung Neoplasms', 'MicroRNAs', 'Neovascularization, Physiologic', 'STAT3 Transcription Factor', 'Smoke', 'Tobacco', 'Vascular Endothelial Growth Factor A'] | 26,525,579 | [['C04.697.098.500', 'C23.550.727.098.500'], ['A11.251'], ['A11.436'], ['A11.284.295.588.750', 'A11.284.430.214.190.875.190.880.495'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['G09.330.... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of different types of nanomaterials on their bioaccumulation in a paddy microcosm: a comparison of TiO2 nanoparticles and nanotubes. | We investigated the environmental fate and bioaccumulation of TiO2 nanomaterials in a simplified paddy microcosm over a period of 17 days. Two types of TiO2 nanomaterials, nanoparticles (TiO2-NP) and nanotubes (TiO2-NT), were synthesized to have a negative surface charge. Ti concentrations in the environmental media (w... | ['Agriculture', 'Animals', 'Aquatic Organisms', 'Ecosystem', 'Environmental Monitoring', 'Food Chain', 'Nanostructures', 'Oryza', 'Titanium', 'Water Pollutants, Chemical'] | 23,583,672 | [['J01.040'], ['B01.050'], ['B05.080', 'G16.500.275.725.500.650.075'], ['G16.500.275.157', 'N06.230.124'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G16.500.275.157.250', 'N06.230.124.250'], ['J01.637.512'], ['B01.650.940.800.575.912.250.822.616'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800'], ['D27.88... | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Tolerability of long-term fluconazole therapy. | BACKGROUND: Fluconazole is a commonly prescribed first-generation triazole antifungal. Although the toxicity profile of fluconazole has been evaluated in clinical trials, there are scant data regarding its tolerability with long-term therapy. Treatment guidelines for coccidioidomycosis recommend fluconazole therapy and... | ['Adult', 'Antifungal Agents', 'Coccidioidomycosis', 'Drug-Related Side Effects and Adverse Reactions', 'Female', 'Fluconazole', 'Humans', 'Male', 'Retrospective Studies', 'Time Factors', 'Treatment Outcome'] | 30,535,104 | [['M01.060.116'], ['D27.505.954.122.136'], ['C01.150.703.203'], ['C25.100'], ['D03.383.129.799.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
MRI correlates of protein deposition and disease severity in postmortem frontotemporal lobar degeneration. | BACKGROUND: Frontotemporal lobar degeneration (FTLD) can be classified based on the presence of the microtubule-associated protein tau and the TAR DNA binding protein-43 (TDP-43). Future treatments will likely target these proteins, therefore it is important to identify biomarkers to help predict protein biochemistry.O... | ['Adult', 'Aged', 'Aged, 80 and over', 'Autopsy', 'DNA-Binding Proteins', 'Dementia', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'tau Proteins'] | 19,299,900 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['D12.776.260'], ['C10.228.140.380', 'F03.615.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.825.500'], ['M01.060.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 |
Evolution of exceptional species richness among lineages of fleshy-fruited Myrtaceae. | BACKGROUND AND AIMS: The angiosperm family Myrtaceae comprises 17 tribes with more than half of the estimated 5500 species being referred to the fleshy-fruited and predominantly rainforest associated Syzygieae and Myrteae. Previous studies suggest that fleshy fruits have evolved separately in these lineages, whereas ge... | ['Bayes Theorem', 'Evolution, Molecular', 'Fruit', 'Myrtaceae', 'Phylogeny', 'Plasmids'] | 20,462,850 | [['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['G05.045.250', 'G16.075.250'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['B01.650.940.800.575.912.250.773'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G05.360.600']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Classification of Setaria worms from calves and adult cattle into Setaria digitata and Setaria marshalli by polyacrylamide gel electrophoresis. | The protein profiles of solubilized whole worms of the species, Setaria digitata and Setaria marshalli were compared using sodium dodecyl sulfate polyacrylamide gel electrophoresis. The results showed that one band with a molecular size of 69 kDa was confirmed only in S. marshalli, while this band was not detected in S... | ['Animals', 'Cattle', 'Electrophoresis, Gel, Two-Dimensional', 'Electrophoresis, Polyacrylamide Gel', 'Female', 'Helminth Proteins', 'Male', 'Setaria Nematode'] | 9,440,202 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.196.401.250', 'E05.301.300.230'], ['E05.196.401.402', 'E05.301.300.319'], ['D12.776.419'], ['B01.050.500.500.294.400.937.463.700']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Research Ethics Considerations Regarding the Cancer Moonshot Initiative. | If the Precision Medicine Initiative was the launching pad, the Cancer Moonshot Initiative is the liftoff. A billion-dollar mission to "eliminate cancer as we know it," the Cancer Moonshot Initiative underscores the Precision Medicine Initiative's near-term focus in oncology research and translation. Spearheaded by Vic... | ['Biomedical Research', 'Ethics, Research', 'Humans', 'Neoplasms', 'Precision Medicine', 'United States'] | 27,314,185 | [['H01.770.644.145'], ['K01.752.566.479.173', 'N05.350.670'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['E02.782', 'H02.403.200.700'], ['Z01.107.567.875']] | ['Disciplines and Occupations [H]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Spinal subdural hematoma, neurilemmoma, and acute transverse myelopathy. | A 74-year-old woman had acute cervical transverse myelopathy from a neurilemmoma. Although extremely rare, the possibility of tumor should be recognized in patients with apparently spontaneous spinal subdural hematoma. As in other cases of compressive myelopathy, early operation is essential for recovery of neurologica... | ['Acute Disease', 'Aged', 'Female', 'Hematoma, Subdural', 'Humans', 'Neurilemmoma', 'Spinal Cord Compression', 'Spinal Cord Diseases', 'Spinal Cord Neoplasms'] | 3,975,824 | [['C23.550.291.125'], ['M01.060.116.100'], ['C10.228.140.300.535.450.400', 'C10.900.300.837.600', 'C14.907.253.573.400.450', 'C23.550.414.838.700', 'C23.550.414.913.700', 'C26.915.300.490.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.595', 'C04.557.580.600.610.595', 'C04.557.580.625.650.... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Double-sides sticking mechanism of vinblastine interacting with á,â-tubulin to get activity against cancer cells. | Vinblastine (VLB) and its derivatives have been used for clinical first-line drugs to treat various cancers. Due to the resistance and serious side effects from using VLB and its derivatives, there is a need to discover and develop novel VLB derivatives with high activity against cancer cells. In order to better discov... | ['Antineoplastic Agents', 'Cell Line, Tumor', 'Humans', 'Molecular Docking Simulation', 'Molecular Dynamics Simulation', 'Protein Conformation', 'Structure-Activity Relationship', 'Tubulin', 'Tubulin Modulators', 'Vinblastine'] | 30,451,089 | [['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595.249', 'L01.224.160.249'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['G02.111.570.820.709'], ['G02.111.830', 'G07.690.773.997'], ['D05.750.078.734.800', 'D12.776.220.600.800', 'D... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
RpkA, a highly conserved GPCR with a lipid kinase domain, has a role in phagocytosis and anti-bacterial defense. | RpkA (Receptor phosphatidylinositol kinase A) is an unusual seven-helix transmembrane protein of Dictyostelium discoideum with a G protein coupled receptor (GPCR) signature and a C-terminal lipid kinase domain (GPCR-PIPK) predicted as a phosphatidylinositol-4-phosphate 5-kinase. RpkA-homologs are present in all so far ... | ['Legionella pneumophila', 'Phagocytosis', 'Receptors, G-Protein-Coupled'] | 22,073,313 | [['B03.440.400.425.450.450.500', 'B03.660.250.460.460.580'], ['G04.417.350', 'G09.188.665', 'G12.450.564.809', 'G12.688'], ['D12.776.543.750.695']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prognosis-determined rehabilitation of hip fractures. | Hip fracture patients were selected for rehabilitation using a prognostic scheme created by multiple linear discriminant analysis. The outcome of positive or negative rehabilitation prognosis was depicted graphically against time. The majority of patients (77%) who had been admitted from their own homes had a good prog... | ['Aged', 'Aged, 80 and over', 'Femoral Neck Fractures', 'Hip Fractures', 'Home Nursing', 'Homes for the Aged', 'Humans', 'Length of Stay', 'Nursing Homes', 'Patient Readmission', 'Predictive Value of Tests', 'Prognosis', 'Regression Analysis'] | 3,197,049 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C26.404.061.425.500', 'C26.531.750.500', 'C26.558.276.425.500'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['E02.760.611.470', 'N02.421.143.524.470', 'N02.421.533.320'], ['J03.775.462', 'N02.278.825.462'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Insulin-like effects on liver Golgi membrane preparations of bis(oxalato)oxovanadate(IV) complex ion, a new vanadate compound. | Recent studies have shown the insulin-like effect of vanadyl sulphate or sodium ortho (or meta-)vanadate administered orally to rats. Toxicity of these drugs and reluctance by the animals to drink the solutions and take food, concerning the amelioration of some diabetes syndrome discussed in 1994 by Domingo et al. (1),... | ['Animals', 'Blood Glucose', 'Diabetes Mellitus, Experimental', 'Female', 'Galactose', 'Galactosyltransferases', 'Golgi Apparatus', 'Insulin', 'Intracellular Membranes', 'Liver', 'Oxalates', 'Rats', 'Rats, Wistar', 'Vanadates', 'Vanadium'] | 9,137,978 | [['B01.050'], ['D09.947.875.359.448.500'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['D09.947.875.359.377'], ['D08.811.913.400.450.400'], ['A11.284.430.214.190.875.336'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['A11.284.149.450', 'A11.284.835.514'], ['A03.620'], ['D02.241.081.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term outcome after treatment of feline inappropriate elimination. | Urination and defecation outside the litter box is one of the most common behavior problems reported by cat caretakers and the most common behavioral reason that results in the relinquishment of cats to shelters. A physical examination, laboratory tests, and a thorough behavioral history are necessary to differentiate ... | ['Animals', 'Behavior Therapy', 'Cats', 'Eliminative Behavior, Animal', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Ownership', 'Surveys and Questionnaires', 'Treatment Outcome'] | 16,221,080 | [['B01.050'], ['F04.754.137'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['F01.145.113.367'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['I01.880.604.583.594', 'N04.452.633'], ['E05.318.308.980', 'N05.715.360.300.80... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
The DSM-III in Canada: a survey. | A survey of the membership of the Canadian Psychiatric Association (CPA) was completed for the Scientific Council to discover, first, the reaction of the members to the Diagnostic and Statistical Manual, Third Edition (DSM-III) and second, the support given to the CPA Policy of not endorsing a particular classification... | ['Canada', 'Data Collection', 'Humans', 'Mental Disorders', 'Psychiatry', 'Societies, Medical'] | 6,850,498 | [['Z01.107.567.176'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['F04.096.544', 'H02.403.690'], ['N03.540.828.589']] | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
ST-elevation myocardial infarction in a young adult secondary to giant coronary aneurysm thrombosis: an important sequela of Kawasaki disease and a management challenge. | Thrombosis of a coronary artery aneurysm (CAA) is a rare trigger for ST-elevation myocardial infarction (STEMI) and an important cause of STEMI in young adults previously affected by Kawasaki disease. Initial management should proceed in line with standard STEMI-management guidelines advocating antiplatelet medication ... | ['Adult', 'Chest Pain', 'Coronary Aneurysm', 'Coronary Angiography', 'Coronary Thrombosis', 'Electrocardiography', 'Female', 'Heart Conduction System', 'Humans', 'Mucocutaneous Lymph Node Syndrome', 'Myocardial Infarction', 'Shock, Cardiogenic', 'Treatment Outcome'] | 26,791,126 | [['M01.060.116'], ['C23.888.592.612.233'], ['C14.280.647.250.250', 'C14.907.055.395', 'C14.907.585.250.250'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250.290', 'C14.907.355.830.220', 'C14.907.585.250.290'], ['E01.370.370.380.240', 'E01.370.405.240'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Clinical experience in treatment of glaucoma with timolol (author's transl)]. | Forty patients with primary and secondary glaucoma were treated with the beta-blocking agent Timolol for six months. We used a 0.25% or 0.5% solution twice a day. In several cases sufficient pressure regulation was achieved by means of Timolol monotherapy. If pilocarpine or acetazolamide therapy was not sufficient we u... | ['Acetazolamide', 'Drug Therapy, Combination', 'Glaucoma', 'Humans', 'Intraocular Pressure', 'Pilocarpine', 'Propanolamines', 'Timolol'] | 7,420,985 | [['D02.886.675.867.060', 'D03.383.129.708.867.060'], ['E02.319.310'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['D03.132.672'], ['D02.033.100.624', 'D02.033.755.624', 'D02.092.063.624'], ['D02.033.100.624.915', 'D02.033.755.624.915', 'D02.092.063.624.915', 'D02.886.675.867.768', 'D... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Small molecule inhibition of protein depalmitoylation as a new approach towards downregulation of oncogenic Ras signalling. | The H- and N-Ras GTPases are prominent examples of proteins, whose localizations and signalling capacities are regulated by reversible palmitoylations and depalmitoylations. Recently, the novel small molecule inhibitor palmostatin B has been described to inhibit Ras depalmitoylation and to revert the phenotype of oncog... | ['Animals', 'Down-Regulation', 'Humans', 'Lipid Metabolism', 'Lipoylation', 'Signal Transduction', 'ras Proteins'] | 21,129,981 | [['B01.050'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.458'], ['G02.111.540', 'G03.458.875'], ['G02.111.820', 'G04.835'], ['D08.811.277.040.330.300.400.500', 'D12.644.360.525.500', 'D12.776.157.325.515.500', 'D12.776.476.525.500']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Variations in daylight as a contextual cue for estimating season, time of day, and weather conditions. | Experience and experiments on human color constancy (i.e., Arend & Reeves, 1986; Craven & Foster, 1992) tell us that we are capable of judging the illumination. However, when asked to make a match of the illuminant's color and brightness, human observers seem to be quite poor (Granzier, Brenner, & Smeets, 2009a). Here ... | ['Color Perception', 'Cues', 'Female', 'Humans', 'Male', 'Orientation', 'Photoperiod', 'Seasons', 'Time Factors', 'Vision, Ocular', 'Weather'] | 24,464,161 | [['F02.463.593.932.217'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.058.577', 'F02.830.606'], ['G01.910.675'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['G01.910.857'], ['F02.830.816.964', 'G02.111.820.480.900', 'G04.835.480.900', 'G11.561.790.964', 'G14.9... | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Prevalence, Knowledge and Attitudes Concerning Dietary Supplements among a Student Population in Croatia. | The aim of this study was to determine the prevalence of usage and the knowledge and attitudes towards dietary supplements among medical sciences and nonmedical sciences students from Croatia. The study was conducted based on a questionnaire about dietary supplement usage, knowledge and attitudes. The prevalence of die... | ['Adolescent', 'Body Mass Index', 'Consumer Health Information', 'Croatia', 'Cross-Sectional Studies', 'Dietary Supplements', 'Exercise', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Internet', 'Male', 'Prevalence', 'Surveys and Questionnaires', 'Vitamins', 'Young Adult'] | 29,882,906 | [['M01.060.057'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['I02.233.332.186', 'N02.421.726.407.229'], ['Z01.542.248.295'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G07.203.300.456', 'J02.500.456'], ['G11.427.410.698.277', 'I03... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Organisms [B]... | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 |
Changes In Learning Style Preferences Of Postgraduates After Entering A New Learning Environment. | BACKGROUND: The aim of this study was to investigate whether the learning style preferences of post-graduate medical students change with time when they enter a new learning environment. The learning styles of post-graduate medical students from Pakistan were assessed on Kolb's Learning style inventory and prospectivel... | ['Adult', 'Education, Medical, Graduate', 'Female', 'Humans', 'Learning', 'Longitudinal Studies', 'Male', 'Pakistan', 'Scotland', 'Students, Medical', 'Surveys and Questionnaires'] | 30,465,378 | [['M01.060.116'], ['I02.358.337.350', 'I02.358.399.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['Z01.252.245.723'], ['Z01.542.363.766'], ['M01.848.769.602'], ['E05.318.308.980', 'N0... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Left atrial abnormalities indicating diastolic ventricular dysfunction in cardiopathy of obesity. | Electrocardiograms and M-mode echocardiograms were evaluated in lean and obese patients, either normotensive or hypertensive, who were paired for mean arterial pressure, age, and sex. Electrocardiographic evidence of left atrial abnormalities (LAA) occurred more frequently (p less than 0.01) and left atrial size was gr... | ['Adult', 'Blood Pressure', 'Body Constitution', 'Cardiomegaly', 'Echocardiography', 'Electrocardiography', 'Female', 'Heart Atria', 'Humans', 'Hypertension', 'Male', 'Obesity'] | 2,960,499 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.115', 'G07.100'], ['C14.280.195', 'C23.300.775.250'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E01.370.370.380.240', 'E01.370.405.240'], ['A07.541.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A dimension reduction approach for modeling multi-locus interaction in case-control studies. | Studying one locus or one single nucleotide polymorphism (SNP) at a time may not be sufficient to understand complex diseases because they are unlikely to result from the effect of only one SNP. Each SNP alone may have little or no effect on the risk of the disease, but together they may increase the risk substantially... | ['Case-Control Studies', 'Chromosome Mapping', 'Computer Simulation', 'Humans', 'Likelihood Functions', 'Logistic Models', 'Models, Genetic', 'Polymorphism, Single Nucleotide'] | 21,734,407 | [['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.393.183'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.360.750.625.450', 'N06.850.520.830.500.475', 'N06.850.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Risk perception and decision processes underlying informed consent to research participation. | According to the rational choice model, informed consent should consist of a systematic, step-by-step evaluation of all information pertinent to the treatment or research participation decision. Research shows that people frequently deviate from this normative model, however, employing decision-making shortcuts, or heu... | ['Adolescent', 'Child', 'Comprehension', 'Decision Making', 'Diabetes Mellitus, Type 1', 'Ethics, Research', 'Female', 'Humans', 'Informed Consent', 'Interviews as Topic', 'Male', 'New England', 'Patient Participation', 'Research Subjects', 'Risk Assessment'] | 17,689,846 | [['M01.060.057'], ['M01.060.406'], ['F02.463.188.357'], ['F02.463.785.373'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['K01.752.566.479.173', 'N05.350.670'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.473.650.718', 'I01.880.604.583.427', 'N03.706.437.650.312', 'N03.706.535.489'], ['E05... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
[Features of erythrocyte aggregation in various forms of bronchial asthma]. | A model of aggregation of erythrocytes was used to study the characteristic features of membrane disorders in different forms of bronchial asthma. It was found that erythrocytic aggregations depended on the form of bronchial asthma, primarily due to the characteristic features of the erythrocytic cellular membrane. In ... | ['Asthma', 'Erythrocyte Aggregation', 'Humans'] | 2,773,448 | [['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['E01.370.225.625.225', 'E05.200.625.225', 'G09.188.370.187'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid estimation of left ventricular contractility from end-systolic relations by echocardiographic automated border detection and femoral arterial pressure. | BACKGROUND: Automated echocardiographic measures of left ventricular (LV) cavity area are closely correlated with changes in volume and can be coupled with LV pressure to construct pressure-area loops in real time. The objective was to rapidly estimate LV contractility from the end-systolic relations of cavity area (as... | ['Adult', 'Aged', 'Blood Pressure', 'Cardiopulmonary Bypass', 'Coronary Artery Bypass', 'Echocardiography, Transesophageal', 'Female', 'Femoral Artery', 'Heart', 'Heart Ventricles', 'Humans', 'Male', 'Middle Aged', 'Myocardial Contraction', 'Stroke Volume', 'Vena Cava, Inferior', 'Ventricular Function', 'Ventricular Fu... | 8,092,499 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E04.292.413'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['A07.015.114.351'], ['A07.541'], ['A07.541.560'], ['B01.050.150.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Comparative colposcopic, cytological and histological studies of the uterine cervix during pregnancy]. | The suspected findings, of colposcopic and cytologic cervix uteri in the pregravidity, was reported. Among 5852 patients, who primarily were directed in the clinic for interruption, 63 of them were examined because of their suspected colposcopic results and 3 cases of them were examined because of their suspected cytol... | ['Abortion, Induced', 'Adult', 'Carcinoma in Situ', 'Colposcopy', 'Female', 'Humans', 'Middle Aged', 'Precancerous Conditions', 'Pregnancy', 'Pregnancy Complications', 'Time Factors', 'Uterine Cervical Neoplasms', 'Vaginal Smears'] | 1,020,511 | [['E04.520.050'], ['M01.060.116'], ['C04.557.470.200.240'], ['E01.370.378.150', 'E01.370.388.250.150', 'E04.502.250.150', 'E04.520.150', 'E04.950.300.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.834'], ['G08.686.784.769'], ['C13.703'], ['G01.910.857'], ['C04.588.945.418.948.850', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Synthesis of [4,5,6,8-(13)C4]guanine, a reagent for the production of internal standards of guanyl DNA adducts. | Using readily available labeled compounds, [4,5,6,8-(13)C4]guanine was synthesized in high overall yield. Intermediates as well as the final product were characterized by 1H NMR, 13C NMR, and high resolution mass spectrometry. The labeled guanine was used to generate [13C4]-labeled analogs of the guanine adducts, N2,3-... | ['Animals', 'Carbon Radioisotopes', 'DNA Adducts', 'Guanine', 'Humans', 'Indicators and Reagents', 'Liver', 'Magnetic Resonance Spectroscopy', 'Rats', 'Spleen'] | 7,578,918 | [['B01.050'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['D13.444.308.135', 'G05.200.104'], ['D03.633.100.759.758.399.454'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.410'], ['A03.620'], ['E05.196.867.519'], ['B01.050.150.900.649.313.992.635.505.700'], ['A10.549.700', 'A15.382.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Insulin potentiates N-methyl-D-aspartate receptor activity in Xenopus oocytes and rat hippocampus. | Growth factor signal transduction pathways have recently been shown to affect voltage-gated ion channel activity. In this study we report that insulin can modulate the activity of a ligand-gated ion channel, the N-methyl-D-aspartate (NMDA) receptor. In Xenopus oocytes, brief insulin exposure rapidly potentiated NR1a/NR... | ['Animals', 'Hippocampus', 'Insulin', 'Oocytes', 'Rats', 'Receptors, N-Methyl-D-Aspartate', 'Signal Transduction', 'Synaptic Transmission', 'Time Factors', 'Xenopus'] | 7,675,309 | [['B01.050'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['A05.360.490.690.680', 'A11.497.497.600'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.157.530.400.400.500.500', 'D12.776.543.550.450.500.200.500', 'D12.776.543.585.400.5... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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