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Higher expression of transcription targets and components of the nuclear factor-kappaB pathway is a distinctive feature of umbilical cord blood CD34+ precursors. | Delayed engraftment, better reconstitution of progenitors, higher thymic function, and a lower incidence of the graft-versus-host disease are characteristics associated with umbilical cord blood (UCB) transplants, compared with bone marrow (BM). To understand the molecular mechanisms causing these intrinsic differences... | ['Adult', 'Antigens, CD34', 'Cord Blood Stem Cell Transplantation', 'DNA Primers', 'Expressed Sequence Tags', 'Gene Expression Regulation', 'Hematopoietic Stem Cells', 'Humans', 'Infant, Newborn', 'NF-kappa B', 'Polymerase Chain Reaction', 'Promoter Regions, Genetic', 'Stem Cells', 'Transcription, Genetic'] | 16,973,832 | [['M01.060.116'], ['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['E02.095.147.500.500.312', 'E04.936.225.687.312'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.360.340.024.340.137.275'], ['G05.308'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B01.050.150.900.649.313.988.400.112.400... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A brain heater in the swordfish. | The brain and eye of swordfish are warmer than the water. Associated with one of the eye muscles is a tissue that heats the brain. This brain heater is rich in mitochondria and cytochrome c and is supplied with blood through a vascular heat exchanger. It protects the central nervous system from rapid cooling during dai... | ['Acclimatization', 'Adipose Tissue', 'Animals', 'Body Temperature Regulation', 'Brain', 'Fishes', 'Hot Temperature', 'Organ Specificity', 'Retina', 'Species Specificity'] | 7,079,766 | [['G07.025.133', 'G16.012.500.133'], ['A10.165.114'], ['B01.050'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['A08.186.211'], ['B01.050.150.900.493'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G07.650'], ['A09.371.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
High-performance liquid chromatographic determination of tramadol and its O-desmethylated metabolite in blood plasma. Application to a bioequivalence study in humans. | Simultaneous HPLC determination of the analgetic agent tramadol, its major pharmacodynamically active metabolite (O-desmethyltramadol) in human plasma is described. Simple methods for the preparation of the standard of the above-mentioned tramadol metabolite and N1,N1-dimethylsulfanilamide (used as the internal standar... | ['Analgesics, Opioid', 'Calibration', 'Chromatography, High Pressure Liquid', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Magnetic Resonance Spectroscopy', 'Reference Standards', 'Reference Values', 'Reproducibility of Results', 'Therapeutic Equivalency', 'Tramadol'] | 11,999,728 | [['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E05.978.155'], ['E05.196.181.400.300'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.867.519'], ['E05.978.808'], ['E05.978.810'], ['E... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Risk factors for recurrence in pT3aN0M0 renal cell carcinoma according to 2009 TNM classification]. | The TNM classification of renal cell carcinoma was updated in 2009. In this new classification system, T3a consists of tumors with renal vein involvement and tumors with fat invasion. To assess risk factors for recurrence, we retrospectively reviewed 89 patients with pT3aN0M0 renal cell carcinoma who underwent radical ... | ['Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Carcinoma, Renal Cell', 'Chemotherapy, Adjuvant', 'Disease-Free Survival', 'Female', 'Humans', 'Interferons', 'Kidney Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Neoplasms, Adipose Tissue', 'Neoplas... | 24,594,765 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['E02.186.170', 'E02.319.170'], ['E01.789.800.190'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of axitinib to downstage cT2a renal tumours and allow partial nephrectomy: a phase II study. | OBJECTIVE: To evaluate the ability of neoadjuvant axitinib to reduce the size of T2 renal cell carcinoma (RCC) for shifting from a radical nephrectomy (RN) to a partial nephrectomy (PN) indication, offering preservation of renal function.PATIENTS AND METHODS: Patients with cT2aN0NxM0 clear-cell RCC, considered not suit... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antineoplastic Agents', 'Axitinib', 'Carcinoma, Renal Cell', 'Drug Administration Schedule', 'Female', 'Humans', 'Kidney Neoplasms', 'Male', 'Middle Aged', 'Neoadjuvant Therapy', 'Neoplasm Staging', 'Nephrectomy', 'Organ Preservation', 'Prospective Studies', 'Treatment Outcome'] | 30,288,884 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248'], ['D02.065.277.051', 'D02.241.223.100.100.115', 'D02.455.426.559.389.127.085.093', 'D03.383.129.539.487.065', 'D03.633.100.449.065'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation of Biochemical, Genetic and Hematological Biomarkers in a Commercial Catfish Rhamdia quelen Exposed to Diclofenac. | Juveniles Rhamdia quelen fish species were exposed to diclofenac for 96 h at concentrations of 0.2, 2, and 20 ìg/L. Biochemical, genetic, and hematological biomarkers were assessed in the liver, kidney, and blood in order to evaluate the toxic effects. No oxidative stress was observed in liver. In kidney the superoxide... | ['Animals', 'Aquaculture', 'Biomarkers', 'Catfishes', 'DNA Damage', 'Diclofenac', 'Kidney', 'Lipid Peroxidation', 'Liver', 'Oxidative Stress', 'Seafood', 'Toxicity Tests, Acute', 'Water Pollutants, Chemical'] | 26,589,900 | [['B01.050'], ['J01.040.168'], ['D23.101'], ['B01.050.150.900.493.080'], ['G05.200'], ['D02.241.223.601.210'], ['A05.810.453'], ['G02.111.515', 'G03.295.531.587'], ['A03.620'], ['G03.673', 'G07.775.750'], ['G07.203.300.600.875', 'J02.500.600.875'], ['E05.940.790'], ['D27.888.284.903.655']] | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Endocytic prolactin routes to the secretory pathway in lactating mammary epithelial cells. | Plasma-borne prolactin is carried from blood to milk by transcytosis across the mammary epithelial cell through the endocytic and secretory pathways. To determine the precise route of prolactin endocytosis, intracellular transport of biotinylated prolactin was monitored, in parallel with endocytosis of fluorescein isot... | ['Animals', 'Arachidonic Acid', 'Breast', 'Caseins', 'Endocytosis', 'Endosomes', 'Epithelial Cells', 'Exocytosis', 'Female', 'Food, Formulated', 'Glycoproteins', 'Golgi Apparatus', 'Lactation', 'Lipids', 'Mannose-Binding Lectins', 'Membrane Glycoproteins', 'Membrane Proteins', 'Microscopy, Electron', 'Prolactin', 'Prot... | 12,206,656 | [['B01.050'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['A01.236'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['G04.417'], ['A11.284.430.214.190.875.190.880.337'], ['A11.436'], ['G04.468'], ['G07.203.300.525.350', 'J02.500.525.350'], ['D09.400.430', 'D12.776.395'], ['A11.284.430.214.190.875.336'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Frequency and characteristics of cognitive services provided in response to a financial incentive. | OBJECTIVE: To determine the effects of a financial incentive on the number and types of cognitive services (CS) provided by community pharmacies to Medicaid recipients in the State of Washington.DESIGN: Prospective randomized trial. CS were reported using a problem-intervention-result coding system over a 20-month peri... | ['Cognition Disorders', 'Humans', 'Prospective Studies'] | 11,029,841 | [['F03.615.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cortical depth dependent population receptive field attraction by spatial attention in human V1. | Visual spatial attention concentrates neural resources at the attended location. Recently, we demonstrated that voluntary spatial attention attracts population receptive fields (pRFs) toward its location throughout the visual hierarchy. Theoretically, both a feed forward or feedback mechanism could underlie pRF attract... | ['Adult', 'Attention', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Pattern Recognition, Visual', 'Space Perception', 'Visual Cortex', 'Young Adult'] | 29,709,626 | [['M01.060.116'], ['F02.830.104.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F02.463.593.778'], ['A08.186.211.200.885.287.500.571.735', 'A08.186.211.200.885.287.500.814.953'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Use of gene expression and pathway signatures to characterize the complexity of human melanoma. | A defining characteristic of most human cancers is heterogeneity, resulting from the somatic acquisition of a complex array of genetic and genomic alterations. Dissecting this heterogeneity is critical to developing an understanding of the underlying mechanisms of disease and to paving the way toward personalized treat... | ['Cluster Analysis', 'Databases, Genetic', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Melanoma', 'Neoplasm Metastasis', 'Signal Transduction', 'Tumor Cells, Cultured'] | 21,641,377 | [['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['E05.393.332'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['C04.697.650', 'C23.550.727.650']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
In situ posterolateral fusion for spondylolisthesis. | In this series spondylolisthesis was treated operatively in children and adolescents who had a displacement greater than 50% even if they were asymptomatic. In youngsters with less than 50% displacement and in adults, operative stabilization was performed if the displacement was progressive or if there were persistent ... | ['Adolescent', 'Adult', 'Child', 'Female', 'Follow-Up Studies', 'Humans', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Spinal Fusion', 'Spondylolisthesis'] | 1,927,342 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['E04.555.100.700'], ['C05.116.900.938.500.500']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Internal jugular vein thrombosis following in-vitro fertilization in a woman with protein S deficiency and heterozygosity for the prothrombin 3' UTR mutation, despite anticoagulation with heparin. | We report the case of a 31-year-old woman with protein S deficiency and heterozygosity for the prothrombin 3' UTR mutation who developed an internal jugular vein thrombosis despite therapeutic anticoagulation with a low molecular weight heparin, following in-vitro fertilization. This case indicates that the stimulus to... | ["3' Untranslated Regions", 'Abortion, Spontaneous', 'Adult', 'Anticoagulants', 'Female', 'Fertilization in Vitro', 'Heparin, Low-Molecular-Weight', 'Heterozygote', 'Humans', 'Jugular Veins', 'Mutation', 'Pregnancy', 'Pregnancy Complications, Cardiovascular', 'Pregnancy Outcome', 'Protein S Deficiency', 'Prothrombin', ... | 11,555,702 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['C13.703.039', 'G08.686.784.769.496.125'], ['M01.060.116'], ['D27.505.954.502.119'], ['E02.875.800.750', 'E05.820.800.750'], ['D09.698.373.400.300'], ['G05.380.383'], ['B01.050.150.900.649.313.988... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The detection of duodenogastric reflux with a non-invasive method using cholescintigraphy. | A non-invasive method to detect duodenogastric reflux is presented. The distribution of a hepatobiliary tracer 99mTc-diethyl-IDA is recorded after an intravenous injection of the substance for one hour. Normally the tracer is excreted through the liver into the biliary tract and into the duodenum, and the further passa... | ['Bile Reflux', 'Biliary Tract', 'Duodenal Diseases', 'Duodenum', 'Gastrointestinal Motility', 'Humans', 'Imino Acids', 'Liver', 'Radionuclide Imaging', 'Stomach', 'Technetium', 'Technetium Tc 99m Diethyl-iminodiacetic Acid'] | 6,941,420 | [['C06.130.140', 'C06.405.748.240.140'], ['A03.159'], ['C06.405.469.275'], ['A03.556.124.684.124', 'A03.556.875.249'], ['G10.261.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.081.583', 'D02.491.485', 'D12.125.072.401'], ['A03.620'], ['E01.370.350.710', 'E01.370.384.730'], ['A03.556.875.875'], ['D01.... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nicotinamide mononucleotide (NMN) supplementation promotes anti-aging miRNA expression profile in the aorta of aged mice, predicting epigenetic rejuvenation and anti-atherogenic effects. | Understanding molecular mechanisms involved in vascular aging is essential to develop novel interventional strategies for treatment and prevention of age-related vascular pathologies. Recent studies provide critical evidence that vascular aging is characterized by NAD+ depletion. Importantly, in aged mice, restoration ... | ['Aging', 'Animals', 'Aorta', 'Atherosclerosis', 'Dietary Supplements', 'Endothelium, Vascular', 'Epigenesis, Genetic', 'Gene Expression Profiling', 'Mice, Inbred C57BL', 'MicroRNAs', 'Nicotinamide Mononucleotide', 'Rejuvenation'] | 31,463,647 | [['G07.345.124'], ['B01.050'], ['A07.015.114.056'], ['C14.907.137.126.307'], ['G07.203.300.456', 'J02.500.456'], ['A07.015.700.500', 'A10.272.491.355'], ['G05.308.203'], ['E05.393.332'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.4... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Familial non-cystic fibrosis mucus inspissation of respiratory tract. | Perlman, M., Williams, J., Hirsch, M., and Bar-Ziv, J. (1975). Archives of Disease in Childhood, 50, 727. Familial non-cystic fibrosis mucus inspissation of respiratory tract. Two sibs, whose parents are first cousins, have had chronic obstructive airways disease from birth with recurrent otitis media, sinusitis, and m... | ['Airway Obstruction', 'Ampicillin', 'Bronchitis', 'Bronchopneumonia', 'Child', 'Child, Preschool', 'Chronic Disease', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Mastoiditis', 'Mucus', 'Otitis Media', 'Physical Therapy Modalities', 'Respiration', 'Sinusitis'] | 1,190,822 | [['C08.618.846.185'], ['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['C01.748.099', 'C08.127.446', 'C08.381.495.146', 'C08.730.099'], ['C01.748.610.127', 'C08.127.509', 'C08.381.677.127', 'C08.730.610.127'], ['M01.060.406'], ['M01.060.406.448'], ['C23.550.291.500'], ['B01.05... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Psychological problems and stomas: a rough guide for community nurses. | There are a reported 100,000 people in the UK with a stoma (McCahon, 1999), and it is thought that about 20% of them will have experienced clinically significant psychological problems following their stoma-forming surgery. This article examines some of the most common problems encountered, and offers suggestions for n... | ['Adaptation, Psychological', 'Body Image', 'Community Health Nursing', 'Humans', 'Ostomy', 'Practice Guidelines as Topic', 'Quality of Life', 'Sexuality', 'Surgical Stomas'] | 15,923,989 | [['F01.058'], ['F01.752.747.792.110', 'F02.463.593.112'], ['H02.478.676.150', 'N02.421.143.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.579'], ['N04.761.700.350.650', 'N05.700.350.650'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['F01.145.802.975', 'G08.686.867'], ['A10.850.720']] | ['Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Evaluating the effectiveness of management practices on hydrology and water quality at watershed scale with a rainfall-runoff model. | The adverse influence of urban development on hydrology and water quality can be reduced by applying best management practices (BMPs) and low impact development (LID) practices. This study applied green roof, rain barrel/cistern, bioretention system, porous pavement, permeable patio, grass strip, grassed swale, wetland... | ['Conservation of Natural Resources', 'Hydrology', 'Models, Theoretical', 'Nitrogen', 'Phosphorus', 'Rain', 'Water Pollutants, Chemical', 'Water Pollution', 'Water Quality', 'Water Supply'] | 25,553,544 | [['J01.256', 'N06.230.080'], ['H01.158.273.248.875', 'H01.277.249.875', 'J01.293.622'], ['E05.599'], ['D01.268.604', 'D01.362.625'], ['D01.268.666'], ['G16.500.175.859', 'G16.500.275.063.725.395', 'G16.500.750.775.450', 'N06.230.300.100.725.450', 'N06.230.520'], ['D27.888.284.903.655'], ['N06.850.460.790'], ['N06.850.4... | ['Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Pseudohypoparathyroidism - epidemiology, mortality and risk of complications. | OBJECTIVE: Pseudohypoparathyroidism (PHP) is caused by a mutation within the GNAS gene or upstream of the GNAS complex locus. It is characterized by target organ resistance to PTH, resulting in hypocalcaemia and hyperphosphataemia. Studies in patients with PHP are limited. We sought to identify all patients in Denmark ... | ['Adolescent', 'Adult', 'Case-Control Studies', 'Cataract', 'Child', 'Child, Preschool', 'Chromogranins', 'Denmark', 'Female', 'GTP-Binding Protein alpha Subunits, Gs', 'Humans', 'Infant', 'Infections', 'Male', 'Mental Disorders', 'Middle Aged', 'Mutation', 'Pseudohypoparathyroidism', 'Seizures', 'Young Adult'] | 26,387,561 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C11.510.245'], ['M01.060.406'], ['M01.060.406.448'], ['D12.776.631.199', 'D12.776.811.185'], ['Z01.542.816.124'], ['D08.811.277.040.330.300.200.100.400', 'D12.644.360.360.100.400', 'D12.776.157.325.332.10... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Expansion of quiescent lung adenocarcinoma CD8+ T cells by MUC1-8-mer peptide-T2 cell-â2 microglobulin complexes. | Adoptive immunotherapy requires the isolation of CD8+ T cells specific for tumor-associated antigens, their expansion in vitro and their transfusion to the patient to mediate a therapeutic effect. MUC1 is an important adenocarcinoma antigen immunogenic for T cells. The MUC1-derived SAPDTRPA (MUC1-8-mer) peptide is a po... | ['Adult', 'Aged', 'CD8-Positive T-Lymphocytes', 'Carcinoma, Non-Small-Cell Lung', 'Cell Line', 'Cell Proliferation', 'Epitopes, T-Lymphocyte', 'Female', 'HLA-A2 Antigen', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Mucin-1', 'T-Lymphocytes, Cytotoxic', 'Tumor Cells, Cultured'] | 26,498,650 | [['M01.060.116'], ['M01.060.116.100'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'], ['D23.050.550.402'], ['D12.776.395.550... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Obesity prevalence and associated factors in the elderly in Pelotas, Rio Grande do Sul State, Brazil: obesity classification according to two cutoff points for body mass index]. | The aim of this study was to estimate obesity prevalence and associated factors in the elderly, according to two cutoff points for body mass index (BMI). This was a cross-sectional, population-based study of a sample of 596 elderly residents in Pelotas, southern Brazil. Nutritional status was evaluated through BMI base... | ['Aged', 'Aged, 80 and over', 'Body Mass Index', 'Brazil', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Obesity', 'Prevalence', 'Reference Values', 'Risk Factors', 'Socioeconomic Factors', 'Urban Population'] | 19,578,578 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['Z01.107.757.176'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C18.654... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Survival and redox activity of Friedmanniomyces endolithicus, an Antarctic endemic black meristematic fungus, after gamma rays exposure. | Despite living organisms are not exposed to acute ionizing radiation under natural conditions, some exhibit a high radiation resistance. Understanding this phenomenon is important for assessing the impact of radiation-related accidents, occupational exposures and space missions. In this context, in this study we analyz... | ['Antarctic Regions', 'Ascomycota', 'Gamma Rays', 'Metabolism', 'Microbial Viability', 'Oxidation-Reduction', 'Pigments, Biological'] | 30,449,360 | [['Z01.158'], ['B01.300.107'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['G03'], ['G06.580'], ['G02.700', 'G03.295.531'], ['D23.767']] | ['Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Developmental expression and subcellular localization of glutaminyl cyclase in mouse brain. | Glutaminyl cyclase (QC) converts N-terminal glutaminyl residues into pyroglutamate (pE), thereby stabilizing these peptides/proteins. Recently, we demonstrated that QC also plays a pathogenic role in Alzheimer's disease by generating the disease-associated pE-Abeta from N-terminally truncated Abeta peptides in vivo. Th... | ['Alzheimer Disease', 'Aminoacyltransferases', 'Amyloid beta-Peptides', 'Animals', 'Brain', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Neurons', 'Organelles', 'Tissue Distribution'] | 19,699,792 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D08.811.913.050.200'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['A08.186.211'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Body size distribution of the dinosaurs. | The distribution of species body size is critically important for determining resource use within a group or clade. It is widely known that non-avian dinosaurs were the largest creatures to roam the Earth. There is, however, little understanding of how maximum species body size was distributed among the dinosaurs. Do t... | ['Animals', 'Biological Evolution', 'Body Size', 'Dinosaurs', 'Fossils'] | 23,284,818 | [['B01.050'], ['G05.045', 'G16.075'], ['E01.370.600.115.100.160', 'E05.041.124.160', 'G07.100.100.160', 'G07.345.249.314'], ['B01.050.150.900.833.150'], ['I01.076.368.584.311']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
[Thrombocytopenia associated with sodium polystyrene sulfonate]. | A 84-year-old man was admitted with diabetes mellitus, hypertension and chronic renal failure in September 1994. In October 1995, his renal function gradually worsened with hyperkalemia. Sodium polystyrene sulfonate (Kayexalate) was administered orally for the treatment of hyperkalemia. However, after 7 days from the s... | ['Aged', 'Aged, 80 and over', 'Humans', 'Hyperkalemia', 'Male', 'Polystyrenes', 'Thrombocytopenia'] | 9,423,342 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.950.396'], ['D02.455.426.559.389.150.750.800.830', 'D05.750.716.579', 'D25.720.716.579', 'J01.637.051.720.716.579'], ['C15.378.140.855']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Mre11-Rad50 promotes rapid repair of DNA damage in the polyploid archaeon Haloferax volcanii by restraining homologous recombination. | Polyploidy is frequent in nature and is a hallmark of cancer cells, but little is known about the strategy of DNA repair in polyploid organisms. We have studied DNA repair in the polyploid archaeon Haloferax volcanii, which contains up to 20 genome copies. We have focused on the role of Mre11 and Rad50 proteins, which ... | ['Archaeal Proteins', 'Cell Survival', 'DNA Breaks, Double-Stranded', 'DNA Repair', 'DNA-Binding Proteins', 'Endodeoxyribonucleases', 'Exodeoxyribonucleases', 'Gene Knockout Techniques', 'Genome, Bacterial', 'Haloferax volcanii', 'Mutation', 'Polyploidy', 'Recombination, Genetic', 'Sequence Deletion', 'Ultraviolet Rays... | 19,593,371 | [['D12.776.090'], ['G04.346'], ['G05.200.210.220'], ['G02.111.222', 'G05.219'], ['D12.776.260'], ['D08.811.277.352.335.350', 'D08.811.277.352.355.325'], ['D08.811.277.352.335.375', 'D08.811.277.352.365.290'], ['E05.393.335.750'], ['G05.360.340.358.207'], ['B02.200.400.400.440.900'], ['G05.365.590'], ['C23.550.210.702',... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A sarcomatous-type peritoneal malign mixed mullerian tumor implant in association with ovarian adenocarcinoma: a case report. | A rare case of a patient with a histopathological diagnosis of a sarcomatous-type peritoneal malign mixed m?llerian tumor implant in association with ovarian adenocarcinoma is reported. A 52-year-old patient was referred to our clinic for an adnexal mass. At pelvic examination, an irregular, fixed, approximately 7-8 cm... | ['Adenocarcinoma', 'Fatal Outcome', 'Female', 'Humans', 'Ileus', 'Middle Aged', 'Mixed Tumor, Mullerian', 'Ovarian Neoplasms', 'Peritoneal Neoplasms', 'Postoperative Complications'] | 18,459,565 | [['C04.557.470.200.025'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531.492'], ['M01.060.116.630'], ['C04.557.435.540'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Arthroscopic anterior cruciate ligament reconstruction with quadriceps tendon-patellar bone autograft. | BACKGROUND: Surgical reconstruction of the anterior cruciate ligament (ACL) is indicated in the ACL-deficient knee with symptomatic instability and multiple ligaments injuries. Bone patellar tendon-bone and the hamstring tendon generally have been used. In the present study, we describe an alternative graft, the quadri... | ['Adult', 'Anterior Cruciate Ligament', 'Anterior Cruciate Ligament Injuries', 'Arthroscopy', 'Baseball', 'Basketball', 'Female', 'Humans', 'Male', 'Patella', 'Tendons', 'Transplantation, Autologous', 'Treatment Outcome'] | 10,217,233 | [['M01.060.116'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['C26.558.554.213'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['I03.450.642.845.110'], ['I03.450.642.845.117'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.043.650.624', 'A02.835.232.730.500'], ['A0... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Reversibility of the haemodynamic effects of anabolic steroids in rats. | The haemodynamic effects of 6 weeks nandrolone decanoate treatment (total dose 30 mg.kg-1) (SG I, n = 12) and their reversibility were studied in anaesthetised, open-chest male rats exposed to 5 min isoproterenol (2.5 micrograms.kg-1) and CaCl2 (25.0 mg.kg-1) loads. In SG I, the heart weight and its ratio to body weigh... | ['Anabolic Agents', 'Animals', 'Calcium Chloride', 'Hemodynamics', 'Isoproterenol', 'Male', 'Nandrolone', 'Nandrolone Decanoate', 'Rats', 'Rats, Inbred Strains', 'Reference Values', 'Time Factors'] | 3,203,656 | [['D27.505.696.399.472.080'], ['B01.050'], ['D01.146.300', 'D01.210.450.150.150'], ['G09.330.380'], ['D02.033.100.291.439', 'D02.092.063.291.439', 'D02.092.311.649', 'D02.455.426.559.389.657.166.175.649'], ['D04.210.500.365.415.638', 'D06.472.334.851.968.976'], ['D04.210.500.365.415.638.500', 'D06.472.334.851.968.976.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genetic structure of North American wolverine (Gulo gulo) populations. | Wolverines (Gulo gulo) are found in low densities throughout their circumpolar distribution. They are also potentially susceptible to human-caused population fragmentation (development, recreation and fur harvesting). The combination of these factors has contributed to this species being listed as having either vulnera... | ['Animals', 'Carnivora', 'DNA', 'Data Interpretation, Statistical', 'Female', 'Genetics, Population', 'Humans', 'Male', 'Microsatellite Repeats', 'North America', 'Phylogeny'] | 11,298,949 | [['B01.050'], ['B01.050.150.900.649.313.750'], ['D13.444.308'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['H01.158.273.343.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Induction of sister chromatid exchange in multiple murine tissues in vivo by various methylating agents. | In order to study the reliability of in vivo sister chromatid exchange (SCE) assays for predicting carcinogenicity, several known animal carcinogens were tested in a multicellular in vivo SCE assay and an in vivo/in vitro murine lymphocyte assay. The methylating agents 1,2-dimethylhydrazine.2 HCl (DMH), dimethylnitrosa... | ['Animals', 'Biotransformation', 'Carcinogenicity Tests', 'Carcinogens', 'Cell Survival', 'DNA Damage', 'Lethal Dose 50', 'Lymphocytes', 'Male', 'Methylation', 'Mice', 'Organ Specificity', 'Sister Chromatid Exchange'] | 2,572,066 | [['B01.050'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['E05.940.150'], ['D27.888.569.100'], ['G04.346'], ['G05.200'], ['E05.940.402', 'G07.225.500', 'G07.690.773.875.750', 'G07.690.936.500.750'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['G02.111.035.538', 'G02.607.094.538', 'G0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunoscintigraphic detection of venous thrombosis of the lower extremities by means of human antifibrin monoclonal antibodies labeled with 111In. | A new monoclonal antibody specific for the beta-chain of human fibrin (C22A) and labeled with 111In has been obtained and successfully used in rabbits and dogs for the in vivo detection of venous thrombosis. Studies in humans are currently ongoing. In order to assess the diagnostic value of 111In-antifibrin for the det... | ['Adult', 'Aged', 'Antibodies, Monoclonal', 'Female', 'Fibrin', 'Humans', 'Indium Radioisotopes', 'Male', 'Middle Aged', 'Phlebography', 'Radionuclide Imaging', 'Sensitivity and Specificity', 'Thrombophlebitis'] | 2,662,832 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.496.749.460'], ['M01.060.116.630'], ['E01.370.350.700.060.600', 'E01.370.370.050.600'], ['E01.370.350.710', 'E... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Steroidogenic acute regulatory protein gene expression, steroid-hormone secretion and proliferative activity of adrenocortical cells in the presence of proteasome inhibitors: in vivo studies on the regenerating rat adrenal cortex. | Previous studies have shown that proteasome inhibitors promote the accumulation of steroidogenic acute regulatory protein (StAR) in cultured rat adrenocortical cells. Unexpectedly, this response was associated with a moderate lowering in the corticosterone secretion and proliferation rate of cultured cells. Hence, we s... | ['Adrenal Cortex', 'Animals', 'Enzyme Inhibitors', 'Female', 'Gene Expression Regulation', 'Leupeptins', 'Phosphoproteins', 'Proteasome Endopeptidase Complex', 'Proteasome Inhibitors', 'Rats', 'Regeneration', 'Steroids'] | 18,425,351 | [['A06.300.071.140'], ['B01.050'], ['D27.505.519.389'], ['G05.308'], ['D12.644.456.580'], ['D12.776.744'], ['D05.500.562.500', 'D08.811.277.656.918', 'D08.811.600.730'], ['D27.505.519.389.745.705'], ['B01.050.150.900.649.313.992.635.505.700'], ['G16.762'], ['D04.210.500']] | ['Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dissecting a popliteal cyst after failed unicompartmental knee arthroplasty. | This report documents the first case of a popliteal cyst in a knee with failed unicompartmental knee arthroplasty (UKA). The cyst was treated successfully with the creation of a small communication hole between the posteromedial compartment and the popliteal cyst under direct arthroscopic visualization. This was follow... | ['Aged', 'Arthroplasty, Replacement, Knee', 'Debridement', 'Female', 'Humans', 'Osteoarthritis', 'Popliteal Cyst', 'Postoperative Complications', 'Recurrence', 'Suction'] | 12,426,547 | [['M01.060.116.100'], ['E04.555.110.110.115', 'E04.650.110.115', 'E04.680.101.110.115'], ['E04.176'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.114.606', 'C05.799.613'], ['C04.182.867.500'], ['C23.550.767'], ['C23.550.291.937'], ['E04.237.890']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Clouston's ectodermal dysplasia. A case report with biochemical study of keratin]. | One familial case of ectodermal dysplasia of the Clouston's type is reported. The clinical picture consisted of hypotrichosis and dysonychia with normal sweating. The disease follows dominant autosomal transmission. Histologically, keratin was slightly abnormal. The biochemical study of keratin of hair and nails showed... | ['Child', 'Cysteine', 'Ectodermal Dysplasia', 'Female', 'Genes, Dominant', 'Hair', 'Humans', 'Keratins', 'Nails'] | 610,663 | [['M01.060.406'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['C16.131.077.350', 'C16.131.831.350', 'C16.320.850.250', 'C17.800.804.350', 'C17.800.827.250'], ['G05.360.340.024.340.240', 'G05.420.320'], ['A17.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D05.750.078.593.450... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Brain oxidative stress in the syndrome of mutual aggravation on the model of combined injury in Mongolian gerbils. | General reaction of an organism (survival, body temperature, hematocrit, glycemia) was followed in Mongolian gerbils subjected to isolated head injury (brain ischemia--LD5), to peripheral injury (ischemia of both hind limbs--LD20), and to combined injury (head injury + peripheral injury). In the early period (1 hour) a... | ['Animals', 'Body Temperature', 'Brain', 'Brain Ischemia', 'Cerebral Cortex', 'Female', 'Gerbillinae', 'Glutathione Reductase', 'Hematocrit', 'Hindlimb', 'Ischemia', 'Lipid Peroxidation', 'Male', 'Multiple Trauma', 'Oxidative Stress', 'Superoxide Dismutase', 'Superoxides'] | 11,769,409 | [['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['A08.186.211'], ['C10.228.140.300.150', 'C14.907.253.092'], ['A08.186.211.200.885.287.500'], ['B01.050.150.900.649.313.992.635.300'], ['D08.811.682.667.092'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['A13.473'], ['C23.550.513'], ['G02.111.515', '... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Clinical impact of interlaboratory variation in international normalized ratio determinations. | Variation among laboratories and point-of-care (POC) devices in International Normalized Ratio (INR) determinations for individual patients in the same community was studied. For each patient, blood samples obtained from a single venipuncture followed by a finger stick were tested at three laboratories and with two POC... | ['Anticoagulants', 'Humans', 'International Normalized Ratio', 'Laboratories, Hospital', 'North Dakota', 'Observer Variation', 'Point-of-Care Systems', 'Warfarin'] | 11,329,760 | [['D27.505.954.502.119'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.625.115.320', 'E05.200.625.115.320'], ['N02.278.216.500.968.420', 'N02.278.487.410', 'N04.452.442.452.422.420'], ['Z01.107.567.875.510.525'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', 'N06.850.490.500.250'], ['N04.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Phosphorylation of microtubule-associated proteins from the ovaries of hemipteran insects by MPF and MAP kinase: possible roles in the regulation of microtubules during oogenesis. | Nutritive tubes that link the developing oocytes to the nurse cells in ovarioles of hemipteran insects contain extensive arrays of microtubules. These are established, then later depolymerised, by developmentally regulated processes. Breakdown of the microtubules corresponds with the activation of M-phase promoting fac... | ['Animals', 'Calcium-Calmodulin-Dependent Protein Kinases', 'Female', 'Hemiptera', 'In Vitro Techniques', 'Maturation-Promoting Factor', 'Microtubule-Associated Proteins', 'Microtubules', 'Oogenesis', 'Ovary', 'Phosphorylation'] | 9,846,377 | [['B01.050'], ['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['B01.050.500.131.617.412'], ['E05.481'], ['D08.811.913.696.620.682.700.646.500.984', 'D12.644.360.250.580', 'D12.776.167.200.580', 'D12.776.476.250.580'], ['D12.776.220.600.450', 'D12.776.631.560'], ['A11.284.430.214.190.750.602']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chronic bile duct ligation in the dog: hemodynamic characterization of a portal hypertensive model. | Splanchnic and systemic hemodynamics were measured in six normal dogs and in 18 dogs that had the bile ducts ligated for a period of 8 weeks. In the bile duct-ligated dogs, there was a decrease in arterial pressure (110 +/- 4 mm Hg vs. normal 136 +/- 6 mm Hg; p less than 0.005) and peripheral vascular resistance (4.60 ... | ['Animals', 'Cholestasis', 'Common Bile Duct', 'Disease Models, Animal', 'Dogs', 'Female', 'Hemodynamics', 'Hypertension, Portal', 'Ligation', 'Liver', 'Liver Circulation', 'Male', 'Splanchnic Circulation'] | 6,629,314 | [['B01.050'], ['C06.130.120.135'], ['A03.159.183.079.300'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.750.250.216.200'], ['G09.330.380'], ['C06.552.494'], ['E04.426'], ['A03.620'], ['G09.330.100.881.552'], ['G09.330.100.881']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
First In Vivo Test of Thermoembolization: Turning Tissue Against Itself Using Transcatheter Chemistry in a Porcine Model. | PURPOSE: Embolotherapies are commonly used for management of primary liver cancer. Explant studies of treated livers, however, reveal an untreated tumor in a high fraction of cases. To improve on this, we propose a new concept referred to as thermoembolization. In this technique, the embolic material reacts in local ti... | ['Animals', 'Computed Tomography Angiography', 'Dichloroacetic Acid', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Embolization, Therapeutic', 'Ethiodized Oil', 'Feasibility Studies', 'Hepatic Artery', 'Humans', 'Liver', 'Necrosis', 'Swine'] | 29,872,896 | [['B01.050'], ['E01.370.350.350.810.335', 'E01.370.350.567.250', 'E01.370.350.600.350.700.810.335', 'E01.370.350.700.700.810.335', 'E01.370.350.700.810.810.568', 'E01.370.350.825.810.810.499'], ['D02.241.081.018.214.500', 'D02.455.526.439.196.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.875', 'G0... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Sleep disorders associated with risk of rheumatoid arthritis. | BACKGROUND: Immune disorders impair sleep quality and sleep disorders (SDs) may derange immune function.PURPOSE: The study evaluated the incidence and risk of rheumatoid arthritis (RA) in patients with SDs using a nationwide cohort.METHODS: We recognized the patients with SDs from 1998 to 2002 by using the Taiwan Natio... | ['Adult', 'Arthritis, Rheumatoid', 'Cohort Studies', 'Comorbidity', 'Confidence Intervals', 'Female', 'Humans', 'Male', 'Mass Screening', 'Middle Aged', 'Odds Ratio', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors', 'Sex Distribution', 'Sex Factors', 'Sleep Apnea, Obstructive', 'Taiwan'] | 29,428,977 | [['M01.060.116'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Material and structural characterization of human saphenous vein. | Saphenous vein patch rupture after carotid endarterectomy is an infrequent but devastating complication. This study was undertaken to evaluate the material and structural properties of fresh human saphenous veins to understand the causes of this complication. Segments of saphenous veins were obtained from 22 patients f... | ['Aged', 'Biomechanical Phenomena', 'Female', 'Humans', 'In Vitro Techniques', 'Male', 'Middle Aged', 'Saphenous Vein', 'Stress, Mechanical', 'Tensile Strength'] | 2,231,964 | [['M01.060.116.100'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['M01.060.116.630'], ['A07.015.908.819'], ['G01.374.835'], ['G01.374.850']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Repetition proportion affects masked priming in nonspeeded tasks. | Masked repetition priming is often greater when a larger proportion of trials involve repetition primes, suggesting that a context-sensitive unconscious process may be operating. Two recent studies have failed to obtain an effect of prime proportion in the perceptual identification (PI) task, suggesting that the effect... | ['Attention', 'Cues', 'Decision Making', 'Humans', 'Mental Recall', 'Paired-Associate Learning', 'Perceptual Masking', 'Reaction Time', 'Recognition, Psychology', 'Semantics', 'Unconscious, Psychology'] | 19,451,375 | [['F02.830.104.214'], ['F02.463.425.234'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.641'], ['F02.463.425.952.500'], ['F02.463.593.071.594', 'F02.463.593.932.733', 'G07.888.125.594'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.463.425.540.706'], ['L... | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Clinical study of inner ear hemorrhage-associated sudden deafness and vertigo]. | Objective: To analyze the clinical features and possible pathogenesis of sudden deafenss and vertigo induced by inner ear hemorrhage. Methods: Clinical data of 30 patients with inner ear hemorrhage, from the first affiliated hospital of Sun Yat-sen university during Jan 2016 to May 2017, were retrospectively analyzed. ... | ['Benign Paroxysmal Positional Vertigo', 'Hearing Loss, Sensorineural', 'Hearing Loss, Sudden', 'Hemorrhage', 'Humans', 'Labyrinth Diseases', 'Prognosis', 'Retrospective Studies', 'Vestibular Evoked Myogenic Potentials'] | 31,315,355 | [['C09.218.568.900.883.500', 'C10.597.951.500', 'C23.888.592.958.500'], ['C09.218.458.341.887', 'C10.597.751.418.341.887', 'C23.888.592.763.393.341.887'], ['C09.218.458.341.900', 'C10.597.751.418.341.900', 'C23.888.592.763.393.341.900'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C09.218.568'],... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Arthroscopic reconstruction of the posterior cruciate ligament with use of a quadruple hamstring tendon graft with 3- to 5-year follow-up. | PURPOSE: This study prospectively evaluated 20 patients treated consecutively to determine patient outcomes, efficacy, and complication potential of arthroscopically assisted posterior cruciate ligament (PCL) reconstruction performed with hamstring tendon grafts.METHODS: Twenty patients (15 men and 5 women), each with ... | ['Adult', 'Arthroscopy', 'Female', 'Follow-Up Studies', 'Humans', 'Knee Joint', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Muscular Atrophy', 'Posterior Cruciate Ligament', 'Postoperative Period', 'Prospective Studies', 'Range of Motion, Articular', 'Reconstructive Surgical Procedures', 'Recovery of Function', 'Tendon... | 16,843,813 | [['M01.060.116'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['M01.060.116.630'], ['A02.633.567', 'A10.690.552.500'], ['C10.597.613.612', 'C23.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Apparent diffusion coefficient reproducibility of the pancreas measured at different MR scanners using diffusion-weighted imaging. | PURPOSE: To evaluate the reproducibility of the pancreatic apparent diffusion coefficient (ADC) measured at different MR scanners.MATERIALS AND METHODS: Twenty-four healthy volunteers underwent three consecutive diffusion-weighted imaging (DWI) at a GE 1.5 Tesla (T), a Siemens 1.5 T and a Philips 3.0 T (session 1), and... | ['Adult', 'Diffusion Magnetic Resonance Imaging', 'Equipment Design', 'Equipment Failure Analysis', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Male', 'Pancreas', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Young Adult'] | 24,222,019 | [['M01.060.116'], ['E01.370.350.825.500.150'], ['E05.320'], ['E05.325.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['A03.734'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The public health dashboard: a surveillance model for bioterrorism preparedness. | The City of Milwaukee Health Department piloted a short-term, near real-time syndromic surveillance and communication tool by using an existing secure regional Internet infrastructure. Voluntary, active syndromic case reporting by hospital Emergency Departments was combined with other data streams, including clinical l... | ['Bioterrorism', 'Disaster Planning', 'Emergency Medical Services', 'Emergency Service, Hospital', 'Hospital Planning', 'Humans', 'Models, Organizational', 'Public Health Administration', 'Sentinel Surveillance', 'Syndrome', 'Wisconsin'] | 15,253,519 | [['I01.198.240.856.800.100', 'I01.880.735.900.800.100', 'I01.880.735.950.500.226.100'], ['N06.230.100.035'], ['N02.421.297'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['N03.349.650.250.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.670', 'N04.452.534'], ['N04.452.794... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
A comparison of in vitro toxicity and antifungal efficacy of membrane-active drugs after liposome encapsulation. | The membrane-active ionophores were observed to possess antifungal activity against Candida albicans 336 and were toxic to human erythrocytes. Liposome encapsulation of these drugs significantly reduced their toxicity to erythrocytes but resulted in the loss of their antifungal potency. These results are compared with ... | ['Antifungal Agents', 'Cell Membrane', 'Drug Carriers', 'Drug Compounding', 'Erythrocytes', 'Gramicidin', 'Humans', 'Ionophores', 'Liposomes', 'Polyenes'] | 2,479,067 | [['D27.505.954.122.136'], ['A11.284.149'], ['D26.255.260', 'E02.319.300.380'], ['E05.916.270'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D04.345.566.850.300', 'D12.644.641.850.300', 'D12.776.543.695.221'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.562.374', 'D27.720.395'], ['D25.479.517... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Epidemiology and phylogenetic analysis of VP7 and VP4 genes of rotaviruses circulating in Rawalpindi, Pakistan during 2010. | Human group A rotaviruses (RVAs) possess a large genetic diversity and new RVA strains and G/P genotype combinations are been identified frequently. Only a few studies reporting the distribution and co-circulation of RVA G and P genotypes are available for Pakistan. This hospital based study showed a RVA prevalence rat... | ['Antigens, Viral', 'Capsid Proteins', 'Child, Preschool', 'Genotype', 'Humans', 'Infant', 'Infant, Newborn', 'Molecular Sequence Data', 'Pakistan', 'Phylogeny', 'Prevalence', 'Rotavirus', 'Rotavirus Infections'] | 23,187,023 | [['D23.050.327'], ['D12.776.964.970.600.550'], ['M01.060.406.448'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['L01.453.245.667'], ['Z01.252.245.723'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
[Bladder dysfunction caused by a large presacral retention mucocele]. | Large pelvic masses can displace the urinary bladder and cause bladder dysfunction with various symptoms. We report the case of a 42-year-old man who described a feeling of reduced urinary stream and bladder filling and residual urine since his youth. After various unsuccessful conservative treatments, the patient was ... | ['Adult', 'Anus, Imperforate', 'Cystoscopy', 'Diagnosis, Differential', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Mucocele', 'Postoperative Complications', 'Recurrence', 'Reoperation', 'Sacrum', 'Suction', 'Tomography, X-Ray Computed', 'Urinary Retention', 'Urination Disorders', 'Urography'] | 20,349,032 | [['M01.060.116'], ['C06.198.050', 'C16.131.314.094'], ['E01.370.388.250.180', 'E01.370.390.175', 'E04.502.250.180', 'E04.950.774.155'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C04.182.511'], ['C23.550.767'], ['C23.550.291.937'], ['E04.690'], ['A02.835.232.834.717'], ['E0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Loss of external rotation following anterior capsulorrhaphy of the shoulder. | A retrospective study was performed on twenty shoulders in nineteen patients who had been managed for severe loss of external rotation of the glenohumeral joint after a previous anterior capsulorrhaphy for recurrent instability. All patients had noted a restricted range of motion, and seventeen shoulders had been painf... | ['Adolescent', 'Adult', 'Arthroplasty', 'Female', 'Follow-Up Studies', 'Humans', 'Joint Instability', 'Male', 'Middle Aged', 'Postoperative Complications', 'Radiography', 'Range of Motion, Articular', 'Reoperation', 'Shoulder Joint', 'Surgical Procedures, Operative', 'Treatment Outcome'] | 8,354,677 | [['M01.060.057'], ['M01.060.116'], ['E04.555.110', 'E04.680.101'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['M01.060.116.630'], ['C23.550.767'], ['E01.370.350.700'], ['E01.370.600.700', 'G11.427.760'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Failure to spread bovine virus diarrhoea virus infection from primarily infected calves despite concurrent infection with bovine coronavirus. | Previous reports on the spread of bovine virus diarrhoea virus (BVDV) from animals primarily infected with the agent are contradictory. In this study, the possibility of transmission of BVDV from calves simultaneously subjected to acute BVDV and bovine coronavirus (BCV) infection was investigated. Ten calves were inocu... | ['Acute Disease', 'Animals', 'Animals, Newborn', 'Bovine Virus Diarrhea-Mucosal Disease', 'Cattle', 'Comorbidity', 'Coronavirus Infections', 'Coronavirus, Bovine', 'Diarrhea Virus 1, Bovine Viral', 'Female', 'Male'] | 12,090,767 | [['C23.550.291.125'], ['B01.050'], ['B01.050.050.282'], ['C01.925.782.350.675.106', 'C22.196.106'], ['B01.050.150.900.649.313.500.380.271'], ['N05.715.350.225', 'N06.850.490.687'], ['C01.925.782.600.550.200'], ['B04.820.578.500.540.150.113.500.750'], ['B04.820.578.344.700.150.100']] | ['Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The pruritus- and TH2-associated cytokine IL-31 promotes growth of sensory nerves. | BACKGROUND: Pruritus is a cardinal symptom of atopic dermatitis, and an increased cutaneous sensory network is thought to contribute to pruritus. Although the immune cell-IL-31-neuron axis has been implicated in severe pruritus during atopic skin inflammation, IL-31's neuropoietic potential remains elusive.OBJECTIVE: W... | ['Animals', 'Cluster Analysis', 'Ganglia, Spinal', 'Gene Expression', 'Gene Expression Profiling', 'Humans', 'Interleukins', 'Mice', 'Mice, Knockout', 'Mice, Transgenic', 'Nerve Fibers', 'Phosphorylation', 'Pruritus', 'STAT3 Transcription Factor', 'Sensory Receptor Cells', 'Skin', 'Th2 Cells'] | 27,212,086 | [['B01.050'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['A08.340.390.340', 'A08.800.350.340', 'A08.800.800.720.725.350'], ['G05.297'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465', 'D12.776.467.374.465', 'D23.529.374.465'], ['B01.050.150.900.649.313.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Association of olfactory bulb volume and olfactory sulcus depth with olfactory function in patients with Parkinson disease. | BACKGROUND AND PURPOSE: Olfactory dysfunction is commonly associated with IPD. We here report the association of OB volume and OS depth with olfactory function in patients with PD.MATERIALS AND METHODS: Morphometric analyses by using MR imaging and the Japanese T&T olfactometer threshold test were used to evaluate olfa... | ['Adult', 'Aged', 'Aged, 80 and over', 'Atrophy', 'Echo-Planar Imaging', 'Female', 'Humans', 'Male', 'Middle Aged', 'Olfaction Disorders', 'Olfactory Bulb', 'Olfactory Pathways', 'Parkinson Disease', 'Sensory Thresholds', 'Smell'] | 21,330,398 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C23.300.070'], ['E01.370.350.825.500.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.597.751.600', 'C23.888.592.763.550'], ['A08.186.211.200.885.388'], ['A08.186.211.180.699', 'A08.612.220.640'], ['C10.228.140.079.862.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Indomethacin-induced intestinal ulcers in rats: effects of salicylazosulfapyridine and dexamethasone. | Characteristics of inflammatory bowel diseases have been hypothesized to resemble those of the syndrome of intestinal ulceration induced in the rat by non-steroidal anti-inflammatory compounds. However, no systematic studies have been undertaken to examine this possibility. Therefore, we have studied the influence of s... | ['Animals', 'Dexamethasone', 'Female', 'Indomethacin', 'Inflammation', 'Intestinal Diseases', 'Rats', 'Sulfasalazine', 'Ulcer'] | 2,864,817 | [['B01.050'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['D03.633.100.473.420'], ['C23.550.470'], ['C06.405.469'], ['B01.050.150.900.649.313.992.635.505.700'], ['D02.065.884.730', 'D02.886.590.700.730'], ['C23.550.891']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of self-relevant perspective-taking on the impact of persuasive appeals. | Donation appeals often describe the situations that confront victims of misfortune and advertisements for consumer products often show people using the products being promoted. When people consider these messages from the perspective of the individuals described in them, they often imagine the reactions they would have... | ['Attention', 'Female', 'Humans', 'Male', 'Persuasive Communication', 'Self Concept', 'Social Perception'] | 24,311,436 | [['F02.830.104.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.143.762'], ['F01.752.747.792'], ['F02.463.593.752']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain. | The transduction of transmembrane electric fields into protein motion has an essential role in the generation and propagation of cellular signals. Voltage-sensing domains (VSDs) carry out these functions through reorientations of positive charges in the S4 helix. Here, we determined crystal structures of the Ciona inte... | ['Amino Acid Sequence', 'Animals', 'Cell Membrane', 'Ciona intestinalis', 'Crystallography, X-Ray', 'Electron Spin Resonance Spectroscopy', 'Electrophysiology', 'Escherichia coli', 'Humans', 'Models, Molecular', 'Molecular Sequence Data', 'Oocytes', 'Protein Structure, Tertiary', 'Sequence Homology, Amino Acid', 'Stati... | 24,487,958 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A11.284.149'], ['B01.050.150.200.727.150.500', 'B01.050.500.272.727.150.500'], ['E05.196.309.742.225'], ['E05.196.867.519.274'], ['H01.158.344.528', 'H01.158.782.236'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.988.400.1... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Platelet monitoring for PCI: which test is the one to choose? | Despite the clinical benefit associated with the combined use of aspirin and clopidogrel in patients with acute coronary syndrome or those undergoing percutaneous coronary intervention, a considerable interindividual variability in response to these drugs have been consistently reported. There is a growing interest on ... | ['Acute Coronary Syndrome', 'Aspirin', 'Blood Platelets', 'Clopidogrel', 'Electric Impedance', 'Humans', 'Platelet Aggregation', 'Platelet Aggregation Inhibitors', 'Prognosis', 'Thromboxane B2', 'Ticlopidine'] | 19,882,078 | [['C14.280.647.124', 'C14.907.585.124'], ['D02.455.426.559.389.657.410.595.176'], ['A11.118.188', 'A15.145.229.188'], ['D02.886.778.823.500.500', 'D03.383.725.849.500.500', 'D03.383.903.830.500.500', 'D03.633.100.928.500.500'], ['G01.358.500.249.277.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.188.370.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Crystal structure of penta-O-acetyl-beta-D-galactopyranose with modeling of the conformation of the acetate groups. | The crystal structure of penta-O-acetyl-beta-D-galactopyranose was determined with Mo K(alpha) radiation at 150 K to R = 0.029. The space group is P2(1)2(1)2(1), and the unit cell dimensions are, a = 8.348, b = 9.021 and c = 25.418 A. The ring has the usual 4C(1) shape and O-6 is in the tg position as frequently observ... | ['Crystallization', 'Crystallography, X-Ray', 'Galactosides', 'Models, Molecular', 'Molecular Structure'] | 12,433,494 | [['E05.196.300', 'G02.171'], ['E05.196.309.742.225'], ['D09.408.320'], ['E05.599.595'], ['G02.111.570', 'G02.466']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Concentrations of glycerides and phospholipids in rat heart and gastrocnemius muscles. Effects of alloxan-diabetes and perfusion. | 1. Methods are described for the extraction of lipid and assay of mono-, di- and tri-glyceride glycerol and phospholipid phosphorus in rat heart and gastrocnemius muscles. 2. In hearts from normal animals, concentrations found were: monoglyceride, 0.6; diglyceride, 0.1; triglyceride, 12.6mumoles of glyceride glycerol/g... | ['Animals', 'Carbon Isotopes', 'Diabetes Mellitus, Experimental', 'Dietary Fats', 'Glucose', 'Glycerides', 'Growth Substances', 'Hydrocortisone', 'Hypophysectomy', 'Insulin', 'Male', 'Muscles', 'Myocardium', 'Oxygen Consumption', 'Perfusion', 'Phospholipids', 'Rats', 'Starvation'] | 6,048,783 | [['B01.050'], ['D01.268.150.075', 'D01.496.123'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['D09.947.875.359.448'], ['D10.351'], ['D27.505.696.377'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['E04.270.532'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
During the pre-dialysis stage of chronic kidney disease, which treatment is associated with better survival in dialysis? | INTRODUCTION: Specialised care of patients in advanced stages of chronic kidney disease (CKD) is associated with better survival in dialysis, but it is not known which treatments specifically favour this outcome.OBJECTIVES: To analyse normal treatment in advanced stages of CKD and establish which treatments are associa... | ['Disease Progression', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Renal Dialysis', 'Renal Insufficiency, Chronic', 'Survival Analysis', 'Survival Rate'] | 25,036,060 | [['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E02.870.300', 'E02.912.800'], ['C12.777.419.780.750', 'C13.351.968.419.780.750'], ['E05.318.740.998', 'N05.715.360.750.795', 'N06.850.5... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evolutionary paths of the cAMP-dependent protein kinase (PKA) catalytic subunits. | 3',5'-cyclic adenosine monophosphate (cAMP) dependent protein kinase or protein kinase A (PKA) has served as a prototype for the large family of protein kinases that are crucially important for signal transduction in eukaryotic cells. The PKA catalytic subunits Cá and Câ, encoded by the two genes PRKACA and PRKACB, res... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Bayes Theorem', 'Chordata', 'Conserved Sequence', 'Cyclic AMP-Dependent Protein Kinase Catalytic Subunits', 'Evolution, Molecular', 'Humans', 'Molecular Sequence Data', 'Multigene Family', 'Phylogeny', 'Protein Structure, Tertiary', 'Retroelements', 'Selection, Genet... | 23,593,352 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['B01.050.150'], ['G02.111.570.580'], ['D08.811.913.696.620.682.700.150.125.750.500', 'D08.811.913.696.620.682.700.150.125.8... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Electrophysiological changes in children with learning and attentional abnormalities as a function of age: event-related potentials to an "oddball" paradigm. | This study investigated age-related electrophysiological differences between children diagnosed with Learning Disabilities (LD), Attention Deficit Hyperactivity Disorder (ADHD), LD-ADHD and Conduct Disorder, using Event-Related Potentials recorded during a two-tone discrimination test. Although age-related (N1 and N2 a... | ['Adult', 'Age Factors', 'Attention Deficit Disorder with Hyperactivity', 'Child', 'Child Behavior Disorders', 'Electroencephalography', 'Event-Related Potentials, P300', 'Evoked Potentials', 'Humans', 'Learning Disabilities'] | 9,783,094 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F03.625.094.150'], ['M01.060.406'], ['F03.625.141'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500.350', 'G11.561.200.500.350'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.150.550', 'C23.8... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Association between major depressive episodes in patients with chronic kidney disease and initiation of dialysis, hospitalization, or death. | CONTEXT: Patients with chronic kidney disease (CKD) experience increased rates of hospitalization and death. Depressive disorders are associated with morbidity and mortality. Whether depression contributes to poor outcomes in patients with CKD not receiving dialysis is unknown.OBJECTIVE: To determine whether the presen... | ['Aged', 'Depressive Disorder, Major', 'Female', 'Humans', 'Kidney Diseases', 'Male', 'Middle Aged', 'Prospective Studies', 'Renal Dialysis', 'Survival Analysis', 'Treatment Outcome', 'United States'] | 20,483,971 | [['M01.060.116.100'], ['F03.600.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419', 'C13.351.968.419'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E02.870.300', 'E02.912.800'], ['E05.318.740.998', 'N05.715.360.750.795', 'N06.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Social anxiety enhances recognition of task-irrelevant threat words. | Past research is mixed regarding the conditions under which memory biases emerge in individuals with high levels of social anxiety. The current study examined whether high social anxiety would be associated with a memory bias for threatening, but task-irrelevant information, or whether it creates a memory bias for both... | ['Adolescent', 'Adult', 'Anxiety', 'Attention', 'Fear', 'Female', 'Humans', 'Male', 'Memory', 'Mental Recall', 'Photic Stimulation', 'Recognition, Psychology', 'Young Adult'] | 30,779,989 | [['M01.060.057'], ['M01.060.116'], ['F01.470.132'], ['F02.830.104.214'], ['F01.470.361'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['F02.463.425.540.641'], ['E05.723.729'], ['F02.463.425.540.706'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Preferences of content of psychological reports for community placement programs. | With the shift toward community-based care for mentally retarded persons has come a change in programming goals aimed more at habilitation. The information from psychological reports is frequently used as one type of information for decision making about clients although such reports have frequently been criticized for... | ['Achievement', 'Activities of Daily Living', 'Community Mental Health Services', 'Humans', 'Intellectual Disability', 'Psychology, Clinical', 'Residential Facilities', 'Social Adjustment'] | 6,660,867 | [['F01.658.059', 'F02.784.629.054'], ['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['F04.408.307', 'N02.421.143.183', 'N02.421.461.232'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['F04.096.628.579'], ['J03.775'... | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 |
[RELATIONSHIP BETWEEN SMOKING AND INDICATORS OF SYSTEMIC INFLAMMATION IN PATIENTS WITH CORONARY HEART DISEASE]. | Aim: To estimate the severity of systemic inflammation in subjects with coronary artery disease (CAD) without bronchopulmonary system comorbidity depending on smoking factor.Materials and methods: The subjects were divided into groups depending on smoking factor. We estimated the following laboratory markers of nonspec... | ['Aged', 'Biomarkers', 'C-Reactive Protein', 'Coronary Artery Disease', 'Correlation of Data', 'Female', 'Humans', 'Inflammation', 'Interleukin-12', 'Interleukin-1beta', 'Male', 'Matrix Metalloproteinase 9', 'Middle Aged', 'Respiratory Function Tests', 'Smoking', 'Tumor Necrosis Factor-alpha'] | 30,303,364 | [['M01.060.116.100'], ['D23.101'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['H01.548.832.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['D12.644.276.374.465.512', 'D12.776.467.374.465.512', 'D23.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Optimizing long-term monitoring of radiation air-dose rates after the Fukushima Daiichi Nuclear Power Plant. | Radiation air dose rates near the Fukushima Daiichi Nuclear Power Plant (FDNPP) have been steadily decreasing over the past eight years since the release of radioactive elements in March 2011. Currently, the radiation monitoring program is expected to transition to long-term monitoring after most of the remediation act... | ['Air Pollutants, Radioactive', 'Bayes Theorem', 'Cesium Radioisotopes', 'Fukushima Nuclear Accident', 'Japan', 'Nuclear Power Plants', 'Radiation Monitoring'] | 32,560,882 | [['D20.693.101', 'D27.888.284.101.393'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['D01.268.549.125.500.300', 'D01.268.556.165.500.300', 'D01.496.180.300', 'D01.496.749.190', 'D01.552.528.160.500.300', 'D01.552.544.165.500.300'], ['K01.400.504.984.186', 'N06.850.135.848.750'], ['Z0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Humanities [K]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Locomotor and verbal distance judgments in action and vista space. | Judging distances is crucial when interacting with the environment. For short distances in action space (up to 30 m), both explicit verbal estimates and locomotor judgments are fairly accurate. For large distances, data have remained scarce. In two laboratory experiments, our observers judged distances to visual target... | ['Adult', 'Distance Perception', 'Female', 'Humans', 'Judgment', 'Male', 'Motor Activity', 'Photic Stimulation', 'Space Perception', 'Verbal Behavior', 'Young Adult'] | 21,365,183 | [['M01.060.116'], ['F02.463.593.200.390', 'F02.463.593.778.255.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.785.626'], ['F01.145.632', 'G11.427.410.698'], ['E05.723.729'], ['F02.463.593.778'], ['F01.145.209.908'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cell-cell mechanical communication through compliant substrates. | The role of matrix mechanics on cell behavior is under intense investigation. Cells exert contractile forces on their matrix and the matrix elasticity can alter these forces and cell migratory behavior. However, little is known about the contribution of matrix mechanics and cell-generated forces to stable cell-cell con... | ['Animals', 'Biomechanical Phenomena', 'Cattle', 'Cell Communication', 'Cell Movement', 'Cells, Cultured', 'Endothelial Cells', 'Extracellular Matrix', 'Stress, Mechanical'] | 18,775,964 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.500.380.271'], ['G04.085'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['A11.436.275'], ['A11.284.295.310'], ['G01.374.835']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Contribution of airway resistance to airway pressure during mechanical ventilation: an experimental study. | Although airway resistance (R) is an important parameter of the pulmonary condition, its determination during mechanical ventilation is not easy. Most physicians estimate R from peak airway pressure during mechanical ventilation. We assessed the relationship between R and peak airway pressure by a computer simulation. ... | ['Airway Resistance', 'Animals', 'Dogs', 'Pulmonary Ventilation'] | 9,972,533 | [['E01.370.386.700.050', 'G09.772.060'], ['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['E01.370.386.700.660', 'G09.772.650']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Safety guidelines for radiolocalised sentinel node resection. | BACKGROUND: Sentinel node radiolocalisation procedures are associated with low levels of radiation exposure. Radioactive material is present in the operating theatre and pathology laboratory. In most hospitals there are no official regulations in place for sentinel node radiation exposure.AIM: To establish guidelines o... | ['Breast Neoplasms', 'Female', 'Guidelines as Topic', 'Humans', 'Occupational Exposure', 'Pathology Department, Hospital', 'Radiation Protection', 'Radiopharmaceuticals', 'Sentinel Lymph Node Biopsy', 'Surgery Department, Hospital', 'Technetium Tc 99m Aggregated Albumin'] | 11,918,328 | [['C04.588.180', 'C17.800.090.500'], ['N04.761.700.350', 'N05.700.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.460.350.600'], ['N02.278.216.500.968.535', 'N04.452.442.452.422.535'], ['N06.850.810.425'], ['D27.505.259.843', 'D27.505.519.871', 'D27.720.470.410.650'], ['E01.370.225.500.384.100.580', '... | ['Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Gene-environment interplay in affect and dementia: emotional modulation of cognitive expression in personal outcomes. | A multitude of factors, that either singly, interactively, or sequentially influence the gene-environment interplay in affective and dementia states, include several phases of neurodevelopmental liability in both humans and laboratory animals. Genetic vulnerability for both affective disorders and dementia describes a ... | ['Adolescent', 'Adult', 'Affect', 'Blood Pressure', 'Cognition', 'Dementia', 'Environment', 'Expressed Emotion', 'Female', 'Humans', 'Interpersonal Relations', 'Male', 'Neuropsychological Tests', 'Personality', 'Personality Assessment', 'Psychiatric Status Rating Scales'] | 15,325,956 | [['M01.060.057'], ['M01.060.116'], ['F01.470.047'], ['E01.370.600.875.249', 'G09.330.380.076'], ['F02.463.188'], ['C10.228.140.380', 'F03.615.400'], ['G16.500.275', 'N06.230'], ['F01.829.197'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F04.711.513'], ['F01.752'], ['F04.513'], ['F04.711.513.653... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of anthropometric characteristics and socio-economic status on physical performances of pre-pubertal children living in Bolivia at low altitude. | We have previously observed that 11-year-old children of low socio-economic status (LSES) showed a delayed physical growth of approximately 2 years and developed lower normalized short-term power output than children of high socio-economic status (HSES) of the same age. In contrast, maximal oxygen uptake (VO2max) per u... | ['Altitude', 'Analysis of Variance', 'Bolivia', 'Child', 'Female', 'Humans', 'Male', 'Nutrition Disorders', 'Oxygen Consumption', 'Sex Factors', 'Social Conditions', 'Value of Life'] | 8,911,830 | [['G16.500.275.058', 'N06.230.058'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['Z01.107.757.136'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.654'], ['G03.680'], ['N05.715.350.675', 'N06.850.490.875'], ['I01.880.853.450', 'N01.824.827'], ['K01.752.400.900']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Optimized dual threshold entity resolution for electronic health record databases--training set size and active learning. | Clinical databases may contain several records for a single patient. Multiple general entity-resolution algorithms have been developed to identify such duplicate records. To achieve optimal accuracy, algorithm parameters must be tuned to a particular dataset. The purpose of this study was to determine the required trai... | ['Algorithms', 'Artificial Intelligence', 'Electronic Health Records', 'Fuzzy Logic'] | 24,551,372 | [['G17.035', 'L01.224.050'], ['G17.035.250', 'L01.224.050.375'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.530.250', 'N06.850.520.308.940.968.625.250'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Humanities [K]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Epidermal growth factor receptor mRNA in peripheral blood of patients with pancreatic, lung, and colon carcinomas detected by RT-PCR. | The epidermal growth factor receptor (EGFR) is overexpressed in many solid tumors. An RT-PCR assay was used to detect EGFR mRNA in the blood of 43 patients with pancreatic, lung (NSCLC), colon, and renal carcinomas. After an initial serum tube was drawn to clear the line of detached epithelial cells, a 3 ml sample of E... | ['Adenocarcinoma', 'Biomarkers, Tumor', 'Blotting, Southern', 'Carcinoma, Non-Small-Cell Lung', 'Carcinoma, Renal Cell', 'Colonic Neoplasms', 'Electrophoresis, Agar Gel', 'ErbB Receptors', 'Humans', 'Kidney Neoplasms', 'Lung Neoplasms', 'Neoplastic Cells, Circulating', 'Pancreatic Neoplasms', 'RNA, Messenger', 'RNA, Ne... | 12,527,944 | [['C04.557.470.200.025'], ['D23.101.140'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.35... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The effect of caffeine on daytime ambulatory blood pressure. | Caffeine produces an acute increase in blood pressure in the research laboratory, but its effect on the ambulatory blood pressure during normal daily activities is unknown. In 25 normotensive, caffeine-naive subjects, daily administration of 400 mg caffeine produced a small increase (+3/+3 mm Hg, P less than .001) in a... | ['Adult', 'Ambulatory Care', 'Blood Pressure', 'Blood Pressure Determination', 'Caffeine', 'Circadian Rhythm', 'Female', 'Humans', 'Male', 'Osmolar Concentration', 'Reference Values', 'Time Factors'] | 2,069,776 | [['M01.060.116'], ['E02.760.106', 'N02.421.585.106'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.140', 'E01.370.600.100'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['G07.180.562.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.640'], ['E05.978.810'], ['G01.910.857']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Extended total temporomandibular joint replacements: a classification system. | Prosthetic total temporomandibular joint (TMJ) replacement (TJR) is well established in the United Kingdom, with clear guidelines for indications and nationally published outcomes. CAD/CAM technology has made it possible to push the boundaries of custom-made TJR to include extended versions (eTJR), which may replace se... | ['Arthroplasty, Replacement', 'Computer-Aided Design', 'Humans', 'Joint Prosthesis', 'Prosthesis Design', 'Temporomandibular Joint Disorders', 'United Kingdom'] | 29,958,720 | [['E04.555.110.110', 'E04.650.110', 'E04.680.101.110'], ['L01.224.108.150', 'L01.296.110.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.400'], ['E05.320.550', 'E07.695.680'], ['C05.500.607.221.897', 'C05.550.905', 'C05.651.243.897', 'C07.320.610.291.897', 'C07.678'], ['Z01.542.363']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Involvement of the ipsilateral and contralateral cerebellum in the acquisition of unilateral classical eyeblink conditioning in guinea pigs. | AIM: The aim of this study was to evaluate the relative contributions of the ipsilateral and contralateral cerebellum to the acquisition of unilateral classical eyeblink conditioning (EBCC).METHODS: The unilateral EBCC was achieved using a binaural tone conditioned stimulus (CS) paired with a left airpuff unconditioned... | ['Animals', 'Blinking', 'Cerebellum', 'Conditioning, Classical', 'Electrophysiology', 'GABA Agonists', 'Guinea Pigs', 'Male', 'Microinjections', 'Muscimol', 'Neurons'] | 19,122,670 | [['B01.050'], ['G11.561.731.127', 'G14.152'], ['A08.186.211.132.810.428.200'], ['F02.463.425.179.308'], ['H01.158.344.528', 'H01.158.782.236'], ['D27.505.519.625.240.200', 'D27.505.696.577.240.200'], ['B01.050.150.900.649.313.992.550'], ['E02.319.267.530.690', 'E05.591.570'], ['D03.383.129.462.470', 'D23.946.587.587'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Drosophila microRNAs 263a/b confer robustness during development by protecting nascent sense organs from apoptosis. | miR-263a/b are members of a conserved family of microRNAs that are expressed in peripheral sense organs across the animal kingdom. Here we present evidence that miR-263a and miR-263b play a role in protecting Drosophila mechanosensory bristles from apoptosis by down-regulating the pro-apoptotic gene head involution def... | ['Animals', 'Apoptosis', 'Base Sequence', 'DNA Primers', 'Drosophila', 'Immunohistochemistry', 'MicroRNAs', 'Microscopy, Electron, Scanning', 'Mutation', 'Sense Organs', 'Transgenes'] | 20,563,308 | [['B01.050'], ['G04.146.954.035'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', '... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of menopause and aging on serum total and ionized calcium and protein concentrations. | The effects of menopause and aging on serum total and ionized calcium concentrations were evaluated in 402 healthy women (aged 18-71 years), of whom 83 were premenopausal and 319 postmenopausal. Serum albumin and globulin concentrations and serum pH were also measured in most of these women. Serum total but not ionized... | ['Adolescent', 'Adult', 'Aged', 'Aging', 'Blood Proteins', 'Calcium', 'Calcium-Binding Proteins', 'Female', 'Humans', 'Hydrogen-Ion Concentration', 'Menopause', 'Middle Aged', 'Serum Albumin', 'Serum Globulins'] | 2,493,324 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['D12.776.124'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['G08.686.157.500', 'G08.686.841.249.500'], ['M01.060.116.630'], ['D12.776.034.841', 'D12.77... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Activation of resting T lymphocytes by anti-CD3 (T3) antibodies in the absence of monocytes. | The antigen receptor molecules on human T lymphocytes are noncovalently associated on the cell surface with the CD3 (T3) molecular complex. Perturbation of this complex with anti-CD3 monoclonal antibodies induces T cell activation. Previous studies have demonstrated that this process requires the participation of monoc... | ['Antibodies, Monoclonal', 'Antigens, Differentiation, T-Lymphocyte', 'Antigens, Surface', 'Cells, Cultured', 'Humans', 'Immunoglobulin Fab Fragments', 'Interleukin-2', 'Lymphocyte Activation', 'Macromolecular Substances', 'Monocytes', 'Receptors, Immunologic', 'Receptors, Interleukin-2', 'T-Lymphocytes', 'Time Factors... | 3,926,881 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.301.264.894', 'D23.101.100.894'], ['D23.050.301'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.541.500.650', 'D12.776.124.486.485.680.650', 'D12.776.124.790.651.680.650', 'D12.776.377.71... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cultivation and stable operation of aerobic granular sludge at low temperature by sieving out the batt-like sludge. | Aerobic granules were successfully cultivated at 10 °C with relatively low strength substrate. Stable granules coexisted with the batt-like sludge (BLS) were obtained in 60 days. After removing the BLS, nutrient removal performance was greatly improved and stable removal efficiencies of 99% phosphorous, 98% ammonia and... | ['Aerobiosis', 'Ammonia', 'Bioreactors', 'Cold Temperature', 'Filtration', 'Phosphorus', 'Sewage', 'Waste Disposal, Fluid'] | 30,223,338 | [['G02.111.017', 'G03.049'], ['D01.362.075', 'D01.625.050'], ['E07.115', 'J01.897.120.115'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['E05.196.454', 'G01.280', 'G02.263'], ['D01.268.666'], ['D20.944.932.500'], ['N06.850.780... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Peroxiredoxin 4 inhibits insulin-induced adipogenesis through regulation of ER stress in 3T3-L1 cells. | Obesity was originally considered a disease endemic to developed countries but has since emerged as a global health problem. Obesity is characterized by abnormal or excessive lipid accumulation (World Health Organization, WHO) resulting from pre-adipocyte differentiation (adipogenesis). The endoplasmic reticulum (ER) p... | ['3T3-L1 Cells', 'Adipocytes', 'Adipogenesis', 'Animals', 'Calcium', 'Endoplasmic Reticulum', 'Endoplasmic Reticulum Stress', 'Gene Expression Regulation', 'Insulin', 'Lipid Metabolism', 'Mice', 'Obesity', 'Peroxiredoxins', 'Reactive Oxygen Species'] | 32,185,676 | [['A11.251.210.100.775.800', 'A11.329.228.100.775.800'], ['A11.329.114'], ['G04.152.149'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.284.430.214.190.875.248'], ['G04.434'], ['G05.308'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.458'], ['B01.050.150.900.649.313... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A contraceptive peptide vaccine targeting sulfated glycoprotein ZP2 of the mouse zona pellucida. | In this study, we have mapped and characterized a B cell epitope of sulfated glycoprotein ZP2 (ZP2) as a step toward the development of a multi-epitope zona pellucida (ZP) vaccine. Recombinant polypeptides expressed by random deoxyribonuclease-digested fragments of ZP2 cDNA were screened for binding to IE-3, a monoclon... | ['Amino Acid Sequence', 'Animals', 'Contraception, Immunologic', 'Egg Proteins', 'Epitope Mapping', 'Epitopes', 'Female', 'Immunoglobulin G', 'Male', 'Membrane Glycoproteins', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C3H', 'Mice, Inbred C57BL', 'Mice, Inbred DBA', 'Molecular Sequence Data', 'Ovariectomy', 'Receptor... | 10,084,964 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E02.875.194.300'], ['D12.776.290'], ['E05.478.274', 'E05.601.690.300'], ['D23.050.550'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['D12.776.395.550', 'D12.776.543.550'], ['B01.050.150.900.649.31... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Anemia in a population from an endemic area of malaria, Rond?nia (Brazil)]. | With the purpose of describing the prevalence rate of anaemia among inhabitants of a malaria endemic area--Candeias district, a periurban locality near Porto Velho, in Rond?nia State, Brazilian Amazon Basin--a random population sample comprehending 1,068 individuals of all age groups (14.1% of the total population) was... | ['Adolescent', 'Anemia, Hemolytic', 'Brazil', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Malaria', 'Male', 'Prevalence'] | 1,342,496 | [['M01.060.057'], ['C15.378.071.141'], ['Z01.107.757.176'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C01.610.752.530', 'C01.920.875'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750']] | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Intestinal schistosomiasis manifesting as colonic intussusception arising from a mucocele of the appendix: report of a case. | We report a case of intestinal schistosomiasis manifesting as colonic intussusception resulting from a mucocele of the appendix, caused by the obstruction of appendiceal outflow by schistosome egg-induced fibrosis. An 81-year-old woman from China presented with a tender right iliac fossa mass and computed tomography (C... | ['Aged, 80 and over', 'Appendix', 'Cecal Diseases', 'Female', 'Humans', 'Intussusception', 'Mucocele', 'Schistosomiasis mansoni', 'Treatment Outcome'] | 18,612,796 | [['M01.060.116.100.080'], ['A03.556.124.526.209.290', 'A03.556.249.249.209.290'], ['C06.405.469.110'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531.577'], ['C04.182.511'], ['C01.610.335.865.859.576', 'C01.920.922.576'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Impact of pregnancy on conversion to clinically isolated syndrome in a radiologically isolated syndrome cohort. | BACKGROUND: In multiple sclerosis (MS), the relapse rate declines during pregnancy and increases during the first three months post-partum before returning to the pre-pregnancy rate. It is unknown whether pregnancy impacts the risk of clinical conversion in those within the presymptomatic period.OBJECTIVES: We investig... | ['Adult', 'Brain', 'Case-Control Studies', 'Demyelinating Diseases', 'Disease Progression', 'Female', 'France', 'Humans', 'Kaplan-Meier Estimate', 'Longitudinal Studies', 'Magnetic Resonance Imaging', 'Middle Aged', 'Predictive Value of Tests', 'Pregnancy', 'Prospective Studies', 'Radiography', 'Risk Assessment', 'Risk... | 22,300,971 | [['M01.060.116'], ['A08.186.211'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C10.314'], ['C23.550.291.656'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['E05.318.372.500.750.500',... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Development of a female attractant for the click beetle pest Agriotes brevis. | BACKGROUND: Traps suitable for catching female Agriotes click beetles may provide better reconnaissance than pheromone-baited traps which catch only males, thereby contributing to more efficient crop protection. The basis for this study came from (i) observations of female Agriotes brevis (Candeze) aggregating beneath ... | ['Acetates', 'Animals', 'Arthropod Antennae', 'Behavior, Animal', 'Coleoptera', 'Female', 'Hexanols', 'Italy', 'Lolium', 'Medicago sativa', 'Pheromones', 'Plant Leaves', 'Salicylates', 'Volatile Organic Compounds'] | 23,749,439 | [['D02.241.081.018', 'D10.251.400.045'], ['B01.050'], ['A13.093'], ['F01.145.113'], ['B01.050.500.131.617.720.500.500.375'], ['D02.033.415.510', 'D10.289.510'], ['Z01.542.489'], ['B01.650.940.800.575.912.250.822.500'], ['B01.650.940.800.575.912.250.401.590.500'], ['D23.641'], ['A18.024.812'], ['D02.241.223.100.300.595'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
The hearing aid revolution: fact or fiction? | OBJECTIVE: To present the experiences of consumers with traditional hearing aids (T-HAs) and digital signal processing hearing aids (DSP-HAs) during the period 1999-2001, based on data obtained from an ongoing quality assurance programme.MATERIAL AND METHODS: A questionnaire is mailed to subjects fitted with HAs 3-4 mo... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Audiometry', 'Correction of Hearing Impairment', 'Cost-Benefit Analysis', 'Denmark', 'Female', 'Forecasting', 'Health Care Surveys', 'Hearing Aids', 'Hearing Disorders', 'Humans', 'Male', 'Middle Aged', 'Patient Satisfaction', 'Persons With Hearing Impairments', 'Pr... | 12,701,750 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.382.375.060'], ['E02.760.169.063.500.200', 'E02.831.200', 'H02.403.680.600.500', 'N02.421.784.377'], ['N03.219.151.125'], ['Z01.542.816.124'], ['I01.320'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.30... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Closed loop ventilation mode in Intensive Care Unit: a randomized controlled clinical trial comparing the numbers of manual ventilator setting changes. | BACKGROUND: There is an equipoise regarding closed-loop ventilation modes and the ability to reduce workload for providers. On one hand some settings are managed by the ventilator but on another hand the automatic mode introduces new settings for the user.METHODS: This randomized controlled trial compared the number of... | ['Aged', 'Blood Gas Analysis', 'Female', 'Humans', 'Intensive Care Units', 'Male', 'Middle Aged', 'Respiration, Artificial'] | 28,679,200 | [['M01.060.116.100'], ['E01.370.225.124.100.100', 'E01.370.386.700.100', 'E05.200.124.100.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.388.493'], ['M01.060.116.630'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Myeloproliferative disease in children: a demographic study. | Over eight years, eight cases of childhood myeloproliferative disease were recognised in the northern region of England (population 3.1 million). Five were classic chronic myeloid leukaemia (CML) and the three others, forms of myeloproliferative disease. No case of juvenile CML was recognised. With the exception of CML... | ['Adolescent', 'Child', 'England', 'Humans', 'Infant', 'Leukemia, Myelogenous, Chronic, BCR-ABL Positive', 'Leukocyte Count', 'Male', 'Myeloproliferative Disorders', 'Platelet Count'] | 3,170,776 | [['M01.060.057'], ['M01.060.406'], ['Z01.542.363.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C04.557.337.539.250', 'C15.378.190.636.370'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.195.107.595', 'G04.140.107.595',... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Random assembly of SUR subunits in K(ATP) channel complexes. | Sulfonylurea receptors (SURs) associate with Kir6.x subunits to form tetradimeric K(ATP) channel complexes. SUR1 and SUR2 confer differential channel sensitivities to nucleotides and pharmacological agents, and are expressed in specific, but overlapping, tissues. This raises the question of whether these different SUR ... | ['ATP-Binding Cassette Transporters', 'Adenosine Triphosphate', 'Animals', 'COS Cells', 'Cell Membrane', 'Chlorocebus aethiops', 'Dimerization', 'Electrophysiology', 'Gene Expression Regulation', 'Ion Channel Gating', 'Models, Statistical', 'Potassium Channels', 'Potassium Channels, Inwardly Rectifying', 'Protein Bindi... | 18,690,055 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['A11.284.149'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['G02.206', 'G0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Soluble and particle-bound trehalase in the silk glands during larval-pupal development of the silkworm, Bombyx mori. | Trehalase localization in silk glands of the silkworm, Bombyx mori has been studied during larval-pupal development. Subcellular distribution of the silk gland trehalase depends upon larval-pupal development. The activity increases in the soluble fraction with a concomitant decrease in the particle-bound fraction durin... | ['Animals', 'Bombyx', 'Exocrine Glands', 'Hydrogen-Ion Concentration', 'Kinetics', 'Larva', 'Pupa', 'Trehalase'] | 6,174,091 | [['B01.050'], ['B01.050.500.131.617.720.500.500.937.650.100'], ['A10.336'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['B05.500.500', 'G07.345.500.550.500.500'], ['B05.500.700', 'G07.345.500.550.500.700'], ['D08.811.277.450.329.865']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
5-HT inhibition of rat insulin 2 promoter Cre recombinase transgene and proopiomelanocortin neuron excitability in the mouse arcuate nucleus. | A number of anti-obesity agents have been developed that enhance hypothalamic 5-HT transmission. Various studies have demonstrated that arcuate neurons, which express proopiomelanocortin peptides (POMC neurons), and neuropeptide Y with agouti-related protein (NPY/AgRP) neurons, are components of the hypothalamic circui... | ['Action Potentials', 'Agouti-Related Protein', 'Animals', 'Arcuate Nucleus of Hypothalamus', 'Biophysical Phenomena', 'Electric Stimulation', 'Green Fluorescent Proteins', 'In Vitro Techniques', 'Insulin Receptor Substrate Proteins', 'Integrases', 'Mice', 'Mice, Transgenic', 'Neural Inhibition', 'Neurons', 'Neuropepti... | 19,135,134 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['D12.644.276.074', 'D12.776.467.074', 'D23.529.074'], ['B01.050'], ['A08.186.211.180.497.352.081', 'A08.186.211.200.317.357.352.081'], ['G01.154'], ['E05.723.402'], ['D12.776.532.265'], ['E05.481'], ['D12.644.360.024.301', 'D12.776.157.057.045', 'D12.776.476.024.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
False positivity of the Aspergillus galactomannan Platelia ELISA because of piperacillin/tazobactam treatment: does it represent a clinical problem? | OBJECTIVES: False-positive results of the galactomannan (GM) ELISA caused by concurrent administration of piperacillin/tazobactam have been reported in patients with febrile neutropenia.PATIENTS AND METHODS: This prospective study investigated different sampling times in 30 patients receiving piperacillin/tazobactam fo... | ['Aged', 'Antigens, Fungal', 'Aspergillosis', 'Aspergillus', 'Enzyme-Linked Immunosorbent Assay', 'False Positive Reactions', 'Humans', 'Mannans', 'Middle Aged', 'Penicillanic Acid', 'Piperacillin', 'Prospective Studies', 'Tazobactam'] | 18,647,743 | [['M01.060.116.100'], ['D23.050.202'], ['C01.150.703.080'], ['B01.300.381.081'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E01.354.506'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.550'], ['M01.060.116.630'], ['D02.065.589.099.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dopaminergic growth patterns induced by striatal and cortical grafts show differences in sensitivity to increased striatal trophic activity induced by haloperidol. | During development, dopaminergic neurons innervate the developing striatal target, forming two different growth patterns: a patchy growth and a diffuse growth. Chronic treatment with the dopamine antagonist haloperidol increase the neurotrophic activity in striatum, but it is not known how this trophic activity influen... | ['Animals', 'Brain Tissue Transplantation', 'Cerebral Cortex', 'Dopamine', 'Dopamine Antagonists', 'Dopamine D2 Receptor Antagonists', 'Enkephalins', 'Female', 'Haloperidol', 'Image Processing, Computer-Assisted', 'Immunohistochemistry', 'Neostriatum', 'Nerve Fibers', 'Rats', 'Rats, Sprague-Dawley', 'Tyrosine 3-Monooxy... | 9,671,973 | [['B01.050'], ['E02.095.147.725.090', 'E04.525.090', 'E04.936.580.090'], ['A08.186.211.200.885.287.500'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D27.505.519.625.150.175', 'D27.505.696.577.150.175'], ['D27.505.519.625.150.175.500', 'D27.505.696.577.150.175.500'], ['D12.644.4... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Reliability and validity of test concepts for the cross-country skiing sprint. | PURPOSE: This study was conducted, first, to develop a test concept for the new cross-country (XC) skiing sprint and to check test reliability and validity, and, secondly, to test the hypothesis that short-duration maximal speed in double poling (DP) predicts DP sprint performance over race distance (1000-1500 m).METHO... | ['Adult', 'Austria', 'Exercise', 'Exercise Test', 'Female', 'Humans', 'Male', 'Skiing'] | 16,540,849 | [['M01.060.116'], ['Z01.542.088'], ['G11.427.410.698.277', 'I03.350'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I03.450.642.845.787.500']] | ['Named Groups [M]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Two mutations remote from an exon/intron junction in the beta-hexosaminidase beta-subunit gene affect 3'-splice site selection and cause Sandhoff disease. | Four unrelated Japanese patients with infantile Sandhoff disease (beta-hexosaminidase beta-subunit deficiency) have been studied for the molecular basis of their severe phenotype. Two patients had complex base substitutions; one patient was homoallelic for a triple mutation (P417L, K121R, and S255R) and the other was a... | ['Animals', 'COS Cells', 'Exons', 'Humans', 'Introns', 'Mutation', 'Polymorphism, Restriction Fragment Length', 'RNA Splicing', 'Sandhoff Disease', 'Sequence Analysis, DNA', 'Transfection', 'beta-N-Acetylhexosaminidases'] | 9,856,491 | [['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['G05.360.340.024.340.137.232'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'], ['G05.365.590'], ['G05.365.795.595'], ['G02.111.760.700', 'G03.839.700', 'G05.308.700.700'], ['C10.228.140.163.100.435.8... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
HEALTHCARE FORECASTING IN THE UNITED ARAB EMIRATES (UAE). | This study has been designed to address the issue of the forecasting of the healthcare needs of the United Arab Emirate (UAE) from 1974 to 2011. This includes predicting the health system's need for hospitals and hospital beds, as well as the public health manpower (example, physicians, nurses) requirements. The analys... | ['Forecasting', 'Health Policy', 'Health Services Needs and Demand', 'Health Services Research', 'Health Workforce', 'Humans', 'Quality Improvement', 'United Arab Emirates'] | 27,483,972 | [['I01.320'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['N03.349.380.420', 'N05.300.450'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['N02.350', 'N04.452.525.500', 'N05.300.420.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.293.754', 'N04.761.744'], ['Z01.252.24... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
Severe anterograde amnesia with extensive hippocampal degeneration in a case of rapidly progressive frontotemporal dementia. | Frontotemporal dementia (FTD) is usually characterized as a spectrum of relatively slowly progressive disorders with largely focal frontal or temporal presentations. The development of clinical and research criteria for discriminating FTD from Alzheimer's disease has relied, in part, on the relative preservation of epi... | ['Amnesia, Anterograde', 'Atrophy', 'Dementia', 'Frontal Lobe', 'Hippocampus', 'Humans', 'Male', 'Middle Aged', 'Temporal Lobe'] | 11,239,076 | [['C10.597.606.525.100.075', 'C23.888.592.604.529.100.075', 'F01.700.625.100.075', 'F03.615.200.137'], ['C23.300.070'], ['C10.228.140.380', 'F03.615.400'], ['A08.186.211.200.885.287.500.270'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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