Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Local Adaptation in European Firs Assessed through Extensive Sampling across Altitudinal Gradients in Southern Europe. | BACKGROUND: Local adaptation is a key driver of phenotypic and genetic divergence at loci responsible for adaptive traits variations in forest tree populations. Its experimental assessment requires rigorous sampling strategies such as those involving population pairs replicated across broad spatial scales.METHODS: A hi... | ['Abies', 'Adaptation, Physiological', 'Altitude', 'Bayes Theorem', 'Climate', 'Computer Simulation', 'DNA, Plant', 'Expressed Sequence Tags', 'Gene Frequency', 'Genetic Variation', 'Genotype', 'Geography', 'Phenotype', 'Polymorphism, Single Nucleotide', 'Trees'] | 27,392,065 | [['B01.650.940.800.575.912.625.875.033'], ['G07.025', 'G16.012.500'], ['G16.500.275.058', 'N06.230.058'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['G16.500.275.071', 'N06.230.300.100.250'], ['L01.224.160'], ['D13.444.308.435'], ['G05.360.340.024.340.137.275'], ['G05.330'], ['G05.3... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[Supportive care in oncology]. | At the present time, cancer can be cured in about 50% of the patients, mainly through surgical procedures associated or not with radiotherapy and/or chemotherapy. For the rest of these patients, therapy will only be palliative; in other words, these patients will not be cured but radiation therapy and/or chemotherapy w... | ['Female', 'Humans', 'Male', 'Neoplasms', 'Palliative Care', 'Prognosis', 'Survival Rate'] | 9,627,440 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['E02.760.666', 'N02.421.585.666'], ['E01.789'], ['E05.318.308.985.550.900', 'N01.224.935.698.826', 'N06.850.505.400.975.550.900', 'N06.850.520.308.985.550.900']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Renal lesions in congenital syphilis. A case report]. | The authors describe a case of congenital syphilitic nephropathy in an infant. The review of the reports in the literature shows many similarities of this congenital disease with the syphilitic nephrotic syndrome in the adult. The prognosis is favorable provided the diagnosis is made sufficiently early. Histological st... | ['Antigens, Bacterial', 'Glomerulonephritis', 'Humans', 'Infant, Newborn', 'Kidney', 'Male', 'Syphilis, Congenital'] | 429,197 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A pilot study of the relationship between bowel habits and sleep health by actigraphy measurement and fecal flora analysis. | We have previously reported that there may be a relationship between bowel habits including functional constipation (FC) and irritable bowel syndrome and sleep health. However, our previous studies were based on only subjective parameters by self-reported questionnaire. The aim of this study is to investigate the relat... | ['Bacteria', 'Colony Count, Microbial', 'Constipation', 'Feces', 'Female', 'Habits', 'Humans', 'Middle Aged', 'Pilot Projects', 'Polysomnography', 'Sleep Wake Disorders'] | 18,536,515 | [['B03'], ['E01.370.225.875.220', 'E05.200.875.220'], ['C23.888.821.150'], ['A12.459'], ['F01.145.466'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E01.370.520.625'], ['C10.886', 'C23.888.592.796', 'F03.870']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Signal detection by the PhoQ sensor-transmitter. Characterization of the sensor domain and a response-impaired mutant that identifies ligand-binding determinants. | The PhoP-PhoQ two-component system is required for virulence and/or regulatory stress responses in enteric bacteria. The PhoQ protein responds to low concentrations of extracellular divalent cations by activating PhoP-mediated transcription of a set of genes. PhoQ is a member of a family of transmembrane proteins that ... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Binding Sites', 'Biosensing Techniques', 'Cations, Divalent', 'Molecular Sequence Data', 'Mutagenesis', 'Protein Denaturation', 'Protein Structure, Secondary', 'Tryptophan'] | 8,900,137 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.120'], ['E05.601.043'], ['D01.248.497.300.333'], ['L01.453.245.667'], ['G05.558'], ['G01.154.651.750.500', 'G02.111.688.750.500'], ['G02.111.570.820.709.600'], ['D12.125.072.050.850', 'D12.125.142.875']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A dark-field light scattering platform for real-time monitoring of the erosion of microparticles by Co2+. | Monitoring chemical reactions using tools of analytical chemistry is crucial for understanding the mechanisms of these reactions. In this study, leaf-like poly(p-phenylenediamine) (PpPD) microparticles were prepared with precisely tailored properties. The dark field microscopy protocol proved to be a powerful tool for ... | ['Cobalt', 'Light', 'Microscopy, Electron, Scanning', 'Microspheres', 'Scattering, Radiation'] | 24,710,388 | [['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E07.565'], ['E05.196.822', 'G01.867']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Medical nutrition therapy for the prevention and treatment of unintentional weight loss in residential healthcare facilities. | OBJECTIVES: To identify the rate of unintentional weight loss (UWL) in adults following their admission into residential healthcare facilities, assess the effectiveness of a new medical nutrition therapy (MNT) protocol for the prevention and treatment of UWL, and describe nutrition assessment and intervention activitie... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Nutrition Assessment', 'Nutrition Disorders', 'Nutritional Requirements', 'Outcome Assessment, Health Care', 'Prospective Studies', 'Residential Facilities', 'Treatment Outcome', 'Weight Loss'] | 12,616,259 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['M01.060.116.630'], ['E05.318.308.585', 'N05.715.360.300.560', 'N06.850.505.557', 'N06.850.520.308.585'], ['C18.654... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 |
In-service light path PMD (polarization mode dispersion) monitoring by PMD compensation. | We describe a novel method of measuring PMD (polarization mode dispersion) of an in-service DWDM system by PMD compensation. We successfully demonstrate the method in a 1500-km ultra-long haul DWDM test bed. We further verify the feasibility of the method for in-service light path PMD monitoring in a field trial in a r... | ['Computer Communication Networks', 'Computer-Aided Design', 'Equipment Design', 'Equipment Failure Analysis', 'Feasibility Studies', 'Fiber Optic Technology', 'Light', 'Photometry', 'Scattering, Radiation'] | 21,197,009 | [['L01.224.230.110'], ['L01.224.108.150', 'L01.296.110.150'], ['E05.320'], ['E05.325.192'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['H01.671.617.249'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E05.196.712'], ['E05.196.822', 'G01.867']] | ['Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Triage of children with headache at the ED: a guideline implementation study. | UNLABELLED: We present a multicenter validation of a modified Manchester Triage System (MTS) flowchart for pediatric patients who present with headache to the emergency department. A prospective observational study was conducted across 5 European pediatric emergency departments. The standard MTS headache flowchart and ... | ['Adolescent', 'Child', 'Child, Preschool', 'Emergency Service, Hospital', 'Female', 'Guideline Adherence', 'Headache', 'Humans', 'Male', 'Prospective Studies', 'Triage'] | 23,380,115 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['N04.761.337', 'N05.715.360.395'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Anaesthetic management of a patient with glycogen storage disease type 1b. | PURPOSE: A rare case of a ten-year old patient with type 1b glycogen storage disease (GSD), scheduled for extracorporeal shockwave lithotripsy (ESWL), is described.CLINICAL FEATURES: Patients with type 1b GSD manifest a range of clinical symptoms, including mental retardation, hepatosplenomegaly, renal enlargement, sto... | ['Anesthesia', 'Child', 'Glycogen Storage Disease Type I', 'Humans', 'Lithotripsy', 'Male'] | 8,723,853 | [['E03.155'], ['M01.060.406'], ['C16.320.565.202.449.448', 'C18.452.648.202.449.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.600', 'E04.943.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Oestrogen receptors interact with the á-catalytic subunit of AMP-activated protein kinase. | Normal and pathological stressors engage the AMP-activated protein kinase (AMPK) signalling axis to protect the cell from energetic pressures. Sex steroid hormones also play a critical role in energy metabolism and significantly modify pathological progression of cardiac disease, diabetes/obesity and cancer. AMPK is ta... | ['AMP-Activated Protein Kinases', 'Breast', 'Breast Neoplasms', 'Catalytic Domain', 'Cell Line', 'Cell Line, Tumor', 'Enzyme Activation', 'Estradiol', 'Estrogen Receptor alpha', 'Estrogen Receptor beta', 'Female', 'Humans'] | 26,374,855 | [['D08.811.913.696.620.682.700.085', 'D12.644.360.062', 'D12.776.476.062'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['A11.251.210'], ['A11.251.210.190', 'A11.251.860.180'], ['G02.111.263', 'G03.328'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.5... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Methionine sulfoxide reductase B1 deficiency does not increase high-fat diet-induced insulin resistance in mice. | Methionine-S-sulfoxide reductase (MsrA) protects against high-fat diet-induced insulin resistance due to its antioxidant effects. To determine whether its counterpart, methionine-R-sulfoxide reductase (MsrB) has similar effects, we compared MsrB1 knockout and wild-type mice using a hyperinsulinemic-euglycemic clamp tec... | ['Animals', 'Blood Glucose', 'Diet, High-Fat', 'Extracellular Signal-Regulated MAP Kinases', 'Insulin Resistance', 'Liver', 'MAP Kinase Kinase 4', 'Male', 'Methionine Sulfoxide Reductases', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Muscle, Skeletal', 'Oxidative Stress', 'Phosphorylation', 'Protein Processing, Post-Trans... | 27,838,938 | [['B01.050'], ['D09.947.875.359.448.500'], ['G07.203.650.240.267'], ['D08.811.913.696.620.682.700.567.249', 'D12.644.360.450.169', 'D12.776.476.450.169'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['A03.620'], ['D08.811.913.696.620.682.700.565.400', 'D08.811.913.696.620.682.725.200.400', 'D12.644.360.440.400', 'D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The use of pulsed field gel electrophoresis to investigate the epidemiology of Staphylococcus aureus infection in commercial broiler flocks. | Pulsed field gel electrophoresis (PFGE) analysis of SmaI restriction patterns was used to type 109 isolates of Staphylococcus aureus collected from broiler farms and hatcheries in Northern Ireland. Forty-seven isolates from clinical conditions in broilers and 62 strains from hatcheries, were examined. The PFGE patterns... | ['Animals', 'Bone and Bones', 'Chickens', 'Comb and Wattles', 'DNA, Bacterial', 'Electrophoresis, Gel, Pulsed-Field', 'Ireland', 'Joints', 'Liver', 'Poultry Diseases', 'Restriction Mapping', 'Staphylococcal Infections', 'Staphylococcus aureus'] | 9,851,005 | [['B01.050'], ['A02.835.232', 'A10.165.265'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A13.242'], ['D13.444.308.212'], ['E05.196.401.220', 'E05.301.300.220'], ['Z01.542.467', 'Z01.639.587'], ['A02.835.583'], ['A03.620'], ['C22.131.728'], ['E05.393.183.620.650', 'E05.393.712'], ['C01.150.252.410... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Congenital stridor secondary to an upper airway cyst in a patient with Ellis-van Creveld syndrome. | We report the occurrence of a pyriform sinus cyst in a patient with Ellis-van Crevald syndrome. The patient presented with congenital stridor. The cyst was drained but recurred. MRI scanning revealed extensive involvement in the neck. Marsupialization and CO2 laser ablation of the lesion was successful, and the patient... | ['Airway Obstruction', 'Cysts', 'Ellis-Van Creveld Syndrome', 'Humans', 'Infant, Newborn', 'Laryngeal Diseases', 'Magnetic Resonance Imaging', 'Otorhinolaryngologic Surgical Procedures', 'Respiratory Sounds'] | 15,869,807 | [['C08.618.846.185'], ['C04.182', 'C23.300.306'], ['C05.116.099.708.327', 'C16.131.077.350.398', 'C16.131.831.350.398', 'C16.320.850.250.398', 'C17.800.804.350.398', 'C17.800.827.250.398'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C08.360', 'C09.400'], ['E01.370.350.825.500'], ['E04.580']... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Innovative Technique in Extended Intramedullary Humeral Lengthening: A Case Report. | CASE: Intramedullary humeral lengthening is still a very uncommon procedure to treat humeral limb length discrepancy (LLD). This approach has various advantages compared with external devices but is limited in its ability to lengthen bones because of the length of the telescopic nail. This case report describes a middl... | ['Bone Lengthening', 'Humans', 'Humerus', 'Male', 'Middle Aged'] | 31,425,164 | [['E04.555.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.087.090.400'], ['M01.060.116.630']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Changes in cardiovascular activity during an increase in biliary tract pressure in rabbits. | In order to study the mechanism of decreased blood pressure caused by an acute increase in biliary tract pressure, we observed house rabbit model of self-made caecus for changes in cardiovascular function when biliary tract pressure was increased. It was found that both the blood pressure and cardiac output evidently d... | ['Animals', 'Biliary Tract', 'Central Venous Pressure', 'Cholangitis', 'Female', 'Hemodynamics', 'Male', 'Pressure', 'Rabbits', 'Splanchnic Nerves'] | 7,807,606 | [['B01.050'], ['A03.159'], ['G09.330.380.076.732.336'], ['C06.130.120.200'], ['G09.330.380'], ['G01.374.715'], ['B01.050.150.900.649.313.968.700'], ['A08.800.050.050.800', 'A08.800.050.800.800', 'A08.800.800.060.800']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High expression of cyclin A is associated with poor prognosis in endometrial endometrioid adenocarcinoma. | Cyclins are a group of proteins that act as activators to cyclin-dependent kinases and are required for normal cell cycle transitions. Cyclin A is involved in the transitions between G1 to S and G2 to M. Its deregulation has been linked to a number of neoplasms, including endometrial cancer. The prognostic significance... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Endometrioid', 'Cyclin A', 'Endometrial Neoplasms', 'Female', 'Humans', 'Immunohistochemistry', 'Middle Aged', 'Neoplasm Staging', 'Prognosis', 'Proportional Hazards Models'] | 24,519,066 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.025.240', 'C04.588.945.418.948.585.124', 'C13.351.500.056.630.705.331', 'C13.351.937.418.685.331', 'C13.351.937.418.875.200.124', 'C19.391.630.705.331'], ['D12.644.360.262.100', 'D12.776.167.218.100', 'D12.776.476... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Prospective assessment of carotid endarterectomy by clinical and ultrasonic methods. | Sixty-three carotid endarterectomies in 60 patients were followed by clinical and duplex scanning at 2 weeks postoperatively and at 3-monthly intervals for 3 years (mean 18 months). Four patients died (two of stroke, two of myocardial infarction) and four survivors had recurrent ipsilateral symptoms. Two had an immedia... | ['Arterial Occlusive Diseases', 'Carotid Arteries', 'Carotid Artery Diseases', 'Endarterectomy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prospective Studies', 'Ultrasonography'] | 3,311,279 | [['C14.907.137'], ['A07.015.114.186'], ['C10.228.140.300.200', 'C14.907.253.123'], ['E04.100.814.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E01.370.350.850']] | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sepsis: a need for prehospital intervention? | Prehospital staff have made a significant contribution in recent years to improving care for patients with acute coronary syndrome, multiple trauma and stroke. There is, however, another group of patients that is not currently being targeted, with a similar time-critical condition. This group of patients is those with ... | ['Anti-Bacterial Agents', 'Communication', 'Critical Illness', 'Emergency Medical Services', 'Emergency Treatment', 'Fluid Therapy', 'Humans', 'Lactic Acid', 'Oxygen', 'Sepsis'] | 19,546,282 | [['D27.505.954.122.085'], ['F01.145.209', 'L01.143'], ['C23.550.291.625'], ['N02.421.297'], ['E02.365'], ['E02.319.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459.450'], ['D01.268.185.550', 'D01.362.670'], ['C01.757', 'C23.550.470.790.500']] | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Methane emissions from free-ranging cattle: comparison of tracer and integrated horizontal flux techniques. | Accurate measurements of methane (CH4) emission rates from livestock in their undisturbed natural environments are required to assess their impacts on radiative forcing (i.e., enhanced greenhouse effect) and the environment. Here we compare results from two nonintrusive techniques for the measurement of CH4 emissions f... | ['Air Pollutants', 'Animals', 'Carbon Dioxide', 'Cattle', 'Dairying', 'Environmental Monitoring', 'Female', 'Methane', 'New Zealand', 'Nitrous Oxide', 'Spectroscopy, Fourier Transform Infrared'] | 18,396,544 | [['D27.888.284.101'], ['B01.050'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['B01.050.150.900.649.313.500.380.271'], ['J01.040.246'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D02.455.326.146.571'], ['Z01.639.760.747', 'Z01.678.100.747'], ['D01.362.635.625', 'D01.625.550.550', 'D01.650.550.587.650'], ['E0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Neutralisation of specific surface carboxylates speeds up translocation of botulinum neurotoxin type B enzymatic domain. | Botulinum neurotoxins translocate their enzymatic domain across vesicular membranes. The molecular triggers of this process are unknown. Here, we tested the possibility that this is elicited by protonation of conserved surface carboxylates. Glutamate-48, glutamate-653 and aspartate-877 were identified as possible candi... | ['Animals', 'Aspartic Acid', 'Botulinum Toxins', 'Botulinum Toxins, Type A', 'Catalytic Domain', 'Cell Membrane', 'Cells, Cultured', 'Cytosol', 'Glutamic Acid', 'Hydrogen-Ion Concentration', 'Mice', 'Mutation', 'Neurons', 'Neurotoxins', 'Protein Transport', 'Protons'] | 24,157,364 | [['B01.050'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['D08.811.277.656.300.480.153', 'D08.811.277.656.675.374.153', 'D12.776.097.156', 'D23.946.123.179'], ['D08.811.277.656.300.480.153.100', 'D08.811.277.656.675.374.153.100', 'D12.776.097.156.100', 'D23.946.123.179.050'], ['G02.111.570.120.704', 'G0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of alpha-tocopherol on premenstrual symptomatology: a double-blind study. | In a double-blind, randomized dose-response study, 75 women with benign breast disease were administered a written questionnaire in which they scored the severity of premenstrual syndrome (PMS) symptoms before and after two months of treatment with placebo or alpha-tocopherol (150, 300, or 600 IU/day). Controlling for ... | ['Adolescent', 'Adult', 'Clinical Trials as Topic', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Female', 'Humans', 'Menstruation Disturbances', 'Middle Aged', 'Premenstrual Syndrome', 'Syndrome', 'Vitamin E'] | 6,350,402 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.568'], ['M01.060.116.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cryoablation of a small pulmonary nodule with pure ground-glass opacity: a case report. | Treatments for pure ground-glass nodules (GGNs) include limited resection; however, surgery is not always possible in patients with limited pulmonary functional reserve. In such patients, cryoablation may be a suitable alternative to treat a pure GGN. Here, we report our initial experience with cryoablation of a pure G... | ['Cryosurgery', 'Female', 'Humans', 'Lung Neoplasms', 'Middle Aged', 'Multiple Pulmonary Nodules', 'Neoplasm Recurrence, Local', 'Tomography, X-Ray Computed'] | 25,995,697 | [['E04.014.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['C04.588.894.797.520.237', 'C08.381.540.148', 'C08.785.520.148'], ['C04.697.655', 'C23.550.727.655'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.70... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Longitudinal and cross-sectional relationships of circulating reproductive hormone levels to self-rated health and health-related quality of life in community-dwelling older men. | CONTEXT: Self-rated health and health-related quality of life are inversely associated with increased morbidity and mortality; however, the temporal relationship with reproductive hormones is poorly understood.OBJECTIVES: The objective of the study was to examine relationships between reproductive hormones, self-rated ... | ['Aged', 'Aged, 80 and over', 'Aging', 'Cross-Sectional Studies', 'Dihydrotestosterone', 'Estradiol', 'Estrone', 'Follicle Stimulating Hormone', 'Health Status', 'Humans', 'Longitudinal Studies', 'Luteinizing Hormone', 'Male', 'Quality of Life', 'Self Report', 'Sex Hormone-Binding Globulin', 'Testosterone'] | 24,552,220 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D04.210.500.054.040.248', 'D06.472.334.851.968.964'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D04.210.500.365.415.414', 'D04.210.500.578.502.497', 'D06.472.0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Structure of a human histone cDNA: evidence that basally expressed histone genes have intervening sequences and encode polyadenylylated mRNAs. | We have isolated and sequenced full-length cDNA clones encoding the human basally expressed H3.3 histone from a human fibroblast cDNA library. Several features of this atypical cDNA distinguish it and its gene from the well-characterized cell-cycle regulated histone genes and their RNA transcripts. The H3.3 mRNA is app... | ['Base Sequence', 'Cell Cycle', 'Cloning, Molecular', 'DNA', 'Gene Amplification', 'Gene Expression Regulation', 'Genes', 'Genetic Variation', 'Histones', 'Humans', 'Poly A', 'RNA, Messenger', 'Transcription, Genetic'] | 2,859,593 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.144'], ['E05.393.220'], ['D13.444.308'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['G05.308'], ['G05.360.340.024.340'], ['G05.365'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Increased activity of the female gonadotropic hormone producing dorsal bodies in Lymnaea stagnalis infected with Trichobilharzia ocellata. | Juvenile specimens of Lymnaea stagnalis were exposed to 0 or 4 miracidia of Trichobilharzia ocellata. Dissection followed at day 22 post exposure. The effects of infection on the activity of the female gonadotropic hormone producing Dorsal Bodies (DB) were studied by phase-contrast and electron microscopy. Morphometry ... | ['Animals', 'Female', 'Golgi Apparatus', 'Gonadotropins', 'Lymnaea', 'Reproduction', 'Schistosomatidae'] | 6,695,535 | [['B01.050'], ['A11.284.430.214.190.875.336'], ['D06.472.699.322'], ['B01.050.500.644.400.750.645'], ['G08.686.784'], ['B01.050.500.500.736.715.770']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular diagnostics, personalized medicine, and the evolving role of the cytotechnologist: an institutional experience. | The role of cytotechnologists has focused primarily on the microscopic examination of cytologic specimens for diagnosing disease. Cytotechnologists currently evaluate a wide assortment of both gynecological and nongynecological cytology specimens. However, the Pap test remains the primary test for most cytology laborat... | ['Biomarkers, Tumor', 'Cytodiagnosis', 'Humans', 'Molecular Diagnostic Techniques', 'Neoplasms', 'Precision Medicine'] | 23,207,447 | [['D23.101.140'], ['E01.370.225.500.384', 'E05.200.500.384', 'E05.242.384'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.880', 'E05.200.880', 'E05.393.520'], ['C04'], ['E02.782', 'H02.403.200.700']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Infection of Female BWF1 Lupus Mice with Malaria Parasite Attenuates B Cell Autoreactivity by Modulating the CXCL12/CXCR4 Axis and Its Downstream Signals PI3K/AKT, NFêB and ERK. | Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by abnormal autoreactivity in B cells. Lymphocytes and their soluble mediators contribute to the disease pathogenesis. We recently demonstrated that infecting lupus mice with malaria confers protection against lupus nephritis by attenua... | ['Animals', 'Autoantibodies', 'B-Cell Activating Factor', 'B-Lymphocytes', 'Cell Proliferation', 'Chemokine CXCL12', 'Disease Models, Animal', 'Female', 'Immunoglobulin G', 'Interferon-alpha', 'Interferon-gamma', 'Interleukins', 'Lupus Erythematosus, Systemic', 'MAP Kinase Signaling System', 'Malaria', 'Mice', 'NF-kapp... | 25,909,640 | [['B01.050'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D12.644.276.374.750.061', 'D12.776.395.191', 'D12.776.467.374.750.061', 'D12.776.543.550.193', 'D23.529.374.750.061'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Neuro-cognitive condition of 8 year old children with congenital hypothyroidism treated early]. | INTRODUCTION: Congenital hypothyroidism is the most important cause of preventable mental retardation. Since the use of programmes for early detection, mental retardation due to cretinism has been abolished and current investigations seek to detect subtle damage due to foetal hypothyroidism and strategies to minimize s... | ['Age Factors', 'Brain Diseases', 'Child', 'Child, Preschool', 'Cognition Disorders', 'Congenital Hypothyroidism', 'Electroencephalography', 'Female', 'Fetal Blood', 'Humans', 'Hypothyroidism', 'Intelligence', 'Male', 'Thyrotropin', 'Thyroxine'] | 10,363,298 | [['N05.715.350.075', 'N06.850.490.250'], ['C10.228.140'], ['M01.060.406'], ['M01.060.406.448'], ['F03.615.250'], ['C05.116.099.343.347', 'C05.116.132.256', 'C16.320.240.625', 'C19.297.155', 'C19.874.482.281'], ['E01.370.376.300', 'E01.370.405.245'], ['A12.207.152.200', 'A15.145.300', 'A16.378.200'], ['B01.050.150.900.6... | ['Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Beliefs underlying stress reduction and depression help-seeking among college students: An elicitation study. | OBJECTIVE: This study illustrates how a theory-based approach can identify college students' beliefs about stress reduction activities and help-seeking for depression. These beliefs are the basis for intervention design.PARTICIPANTS: A sample of 53 undergraduate students at a public university in the Midwest participat... | ['Adult', 'Attitude to Health', 'Depressive Disorder', 'Female', 'Humans', 'Male', 'Minnesota', 'Preventive Health Services', 'Social Stigma', 'Stress, Psychological', 'Students', 'Surveys and Questionnaires', 'Universities', 'Young Adult'] | 29,652,623 | [['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.350.510', 'Z01.107.567.875.510.510'], ['N02.421.726'], ['F01.145.813.840'], ['F01.145.126.990', 'F02.830.900'], ['M01.848'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.9... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Resistin in rheumatoid arthritis synovial tissue, synovial fluid and serum. | BACKGROUND: Resistin is a newly identified adipocytokine which has demonstrated links between obesity and insulin resistance in rodents. In humans, proinflammatory properties of resistin are superior to its insulin resistance-inducing effects.OBJECTIVES: To assess resistin expression in synovial tissues, serum and syno... | ['Adult', 'Aged', 'Arthritis, Rheumatoid', 'Biomarkers', 'Female', 'Humans', 'Immunoenzyme Techniques', 'Inflammation Mediators', 'Male', 'Microscopy, Confocal', 'Middle Aged', 'Osteoarthritis, Knee', 'Resistin', 'Severity of Illness Index', 'Spondylarthropathies', 'Synovial Fluid', 'Synovial Membrane'] | 17,040,961 | [['M01.060.116'], ['M01.060.116.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D23.101'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['D23.469'], ['E01.370.350.515.395', 'E05.595.395'], ['M01.060.116.630'], ['C05.550.114.60... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An integrated approach to NMR spin relaxation in flexible biomolecules: application to beta-D-glucopyranosyl-(1-->6)-alpha-D-mannopyranosyl-OMe. | The description of the reorientational dynamics of flexible molecules is a challenging task, in particular when the rates of internal and global motions are comparable. The commonly used simple mode-decoupling models are based on the assumption of statistical independence between these motions. This assumption is not v... | ['Carbohydrate Conformation', 'Disaccharides', 'Glucose', 'Magnetic Resonance Spectroscopy', 'Mannose', 'Models, Molecular', 'Molecular Dynamics Simulation', 'Motion'] | 20,025,329 | [['G02.111.570.820.235'], ['D09.698.629.305', 'D09.947.750'], ['D09.947.875.359.448'], ['E05.196.867.519'], ['D09.947.875.359.588'], ['E05.599.595'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['G01.482']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Illness-specific catastrophic thinking and overperception in asthma. | OBJECTIVE: This study investigated the role of illness-specific catastrophic thinking in symptom perception in asthma.DESIGN AND MAIN OUTCOME MEASURES: A total sample of 72 patients with intermittent to moderate persistent asthma completed the Catastrophizing about Asthma Scale and completed the Asthma Symptom Checklis... | ['Adolescent', 'Adult', 'Anxiety', 'Asthma', 'Belgium', 'Fear', 'Female', 'Humans', 'Male', 'Surveys and Questionnaires', 'Thinking'] | 18,230,019 | [['M01.060.057'], ['M01.060.116'], ['F01.470.132'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['Z01.542.115'], ['F01.470.361'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['F02.463.785']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Facile green synthesis of gold nanoparticles using leaf extract of antidiabetic potent Cassia auriculata. | A simple biological method for the synthesis of gold nanoparticles (AuNPs) using Cassia auriculata aqueous leaf extract has been carried out in the present study. The reduction of auric chloride led to the formation of AuNPs within 10 min at room temperature (28°C), suggesting a higher reaction rate than chemical metho... | ['Cassia', 'Chlorides', 'Gold', 'Gold Compounds', 'Green Chemistry Technology', 'Hypoglycemic Agents', 'Metal Nanoparticles', 'Plant Extracts', 'Plant Leaves', 'Solutions', 'Spectrophotometry, Ultraviolet', 'Spectroscopy, Fourier Transform Infrared', 'Time Factors', 'X-Ray Diffraction'] | 21,640,563 | [['B01.650.940.800.575.912.250.401.100'], ['D01.210.450.150', 'D01.248.497.158.215'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['D01.379'], ['J01.897.360'], ['D27.505.696.422'], ['J01.637.512.600.500'], ['D20.215.784.500', 'D26.667'], ['A18.024.812'], ['D26.776'], ['E05.196.712.726.802', 'E05.196.867.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Accuracy of self-report and toxicological assays to detect substance misuse disorders in parasuicide patients. | OBJECTIVE: To assess the accuracy of self-reported substance use and toxicological assays in subjects admitted for Intentional Drug Overdose (IDO), using as a reference diagnosis of substance use disorder.METHOD: Self-reported substance use was collected and toxicological assays were carried out in urine samples in 507... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Communication', 'Drug Overdose', 'Emergency Services, Psychiatric', 'Female', 'Humans', 'Male', 'Medical History Taking', 'Middle Aged', 'Self-Assessment', 'Self-Injurious Behavior', 'Sensitivity and Specificity', 'Substance-Related Disorders', 'Toxicology'] | 14,616,221 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.145.209', 'L01.143'], ['C25.775.383', 'E02.319.306.500.500'], ['F04.408.525', 'N02.421.297.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.510'], ['M01.060.116.630'], ['F01.752.747.792.537'], ['F01.145.126.980'], ['... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Flutter of left ventricular structures in patients with aortic regurgitation, with special reference to patients with associated mitral stenosis. | Echocardiography was performed in 45 patients with aortic regurgitation. Forty showed a high frequency diastolic flutter of the mitral valve, which was holodiastolic in all but the patients with associated mitral stenosis. Of four patients with coexisting mitral stenosis, mitral flutter was absent in two; in the other ... | ['Adolescent', 'Adult', 'Aged', 'Aortic Valve Insufficiency', 'Aortography', 'Child', 'Echocardiography', 'Humans', 'Middle Aged', 'Mitral Valve Stenosis', 'Movement'] | 998,474 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C14.280.484.048.500'], ['E01.370.350.700.060.070', 'E01.370.370.050.070'], ['M01.060.406'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.484.517'], ['G07.56... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Stomach perforation in the neonatal period and in children]. | Among the upper gastrointestinal tract perforations in infants and children, the gastric perforations were predominating. With exception of peptic ulcers, localization was found mainly in the upper parts of the stomach regarding to mechanical originating factors. Mortality depends on prematurity and additional injuries... | ['Child', 'Child, Preschool', 'Follow-Up Studies', 'Humans', 'Infant', 'Infant, Newborn', 'Infant, Premature, Diseases', 'Peptic Ulcer Perforation', 'Postoperative Complications', 'Risk Factors', 'Stomach', 'Stomach Rupture'] | 2,330,768 | [['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['C16.614.521'], ['C06.405.469.275.800.698', 'C06.405.748.586.698'], ['C23.550.767'], ['E05.318.740.600... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Estimated cerebral blood flow in term infants with hypoxic-ischemic encephalopathy. | Estimated cerebral blood flow (eCBF) was measured sequentially in seven term infants with evidence of hypoxic-ischemic encephalopathy (HIE) and compared with that of normal-term infants. The eCBF was determined by a noninvasive method involving brief bilateral jugular venous occlusion with simultaneous measurement of o... | ['Asphyxia Neonatorum', 'Blood Pressure', 'Brain Ischemia', 'Carbon Dioxide', 'Cerebrovascular Circulation', 'Female', 'Fetal Hypoxia', 'Humans', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Intracranial Pressure', 'Pregnancy'] | 6,795,582 | [['C16.614.092'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C10.228.140.300.150', 'C14.907.253.092'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['G09.330.100.159'], ['C13.703.277.390', 'C16.300.420', 'C23.888.852.079.594'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614'], ... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cyclophilin A is required for CXCR4-mediated nuclear export of heterogeneous nuclear ribonucleoprotein A2, activation and nuclear translocation of ERK1/2, and chemotactic cell migration. | The chemokine receptor CXCR4-mediated signaling cascades play an important role in cell proliferation and migration, but the underlying mechanisms by which the receptor signaling is regulated remain incompletely understood. Here, we demonstrate that CXCR4 was co-immunoprecipitated with cyclophilin A (CyPA) from the lys... | ['Cell Line', 'Cell Movement', 'Cell Nucleus', 'Chemotaxis', 'Cyclophilin A', 'Flow Cytometry', 'Fluorescent Antibody Technique', 'HeLa Cells', 'Heterogeneous-Nuclear Ribonucleoprotein Group A-B', 'Humans', 'Immunoprecipitation', 'Microscopy, Confocal', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated Protein K... | 17,991,743 | [['A11.251.210'], ['G04.198', 'G07.568.500.180'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['F01.145.113.780.500', 'F01.145.875.439.500.500', 'G04.198.424', 'G07.568.500.590.500', 'G11.427.410.568.850.500'], ['D08.811.399.325.500.400.300.500'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pharmacokinetic-pharmacodynamic relationships of cognitive and psychomotor effects of intravenous buprenorphine infusion in human volunteers. | The main objective of the present study was to characterize the pharmacokinetic/pharmacodynamic (PK/PD) relationship of the effects of buprenorphine on cognitive functioning in healthy volunteers. Twenty-three male volunteers received 0.6 mg buprenorphine as an intravenous infusion over 150 min. The cognitive and psych... | ['Adult', 'Analgesics, Opioid', 'Buprenorphine', 'Cognition', 'Half-Life', 'Humans', 'Infusions, Intravenous', 'Male', 'Nonlinear Dynamics', 'Psychological Tests', 'Psychomotor Performance'] | 18,598,301 | [['M01.060.116'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['D03.132.577.249.150', 'D03.605.497.150', 'D03.633.400.686.150', 'D04.615.723.795.150'], ['F02.463.188'], ['G01.910.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Immunological alterations associated with Plasmodium vivax malaria in South Korea. | Various haematological and immunological studies on patients infected with Plasmodium vivax were undertaken, at diagnosis (day 0), after treatment with chloroquine but during primaquine treatment (day 10) and after all treatment (day 59), in South Korea (where there has been a recent and abrupt increase in the incidenc... | ['Adolescent', 'Adult', 'Antimalarials', 'Biomarkers', 'Case-Control Studies', 'Chloroquine', 'Eosinophils', 'Female', 'Humans', 'Immunoglobulin E', 'Immunoglobulin M', 'Leukocyte Count', 'Leukopenia', 'Lymphocyte Subsets', 'Malaria, Vivax', 'Male', 'Middle Aged', 'Primaquine', 'Thrombocytopenia'] | 11,235,551 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.250.100.085'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D03.633.100.810.050.180'], ['A11.118.637.415.345', 'A11.627.340.345', 'A15.145.229.637.415.345', 'A15.382.490.315.251'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t(8;21)(q24;q22) acute myeloid leukemia. | The Runt domain transcription factor AML1/RUNX1 is essential for the generation of hematopoietic stem cells and is the most frequent target of chromosomal translocations associated with leukemia. Here, we present a new AML1 translocation found in a patient with acute myeloid leukemia M4 with t(8;21)(q24;q22) at the tim... | ['Animals', 'Cell Line', 'Cell Proliferation', 'Cell Transformation, Neoplastic', 'Chromosomes, Human, Pair 21', 'Chromosomes, Human, Pair 8', 'Core Binding Factor Alpha 2 Subunit', 'DNA-Binding Proteins', 'GATA Transcription Factors', 'Hematopoietic Stem Cells', 'Humans', 'Leukemia, Myeloid, Acute', 'Mice', 'Oncogene ... | 17,244,685 | [['B01.050'], ['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.697.098.500', 'C23.550.727.098.500'], ['A11.284.187.520.300.505.510', 'G05.360.162.520.300.505.510'], ['A11.284.187.520.300.325.340', 'G05.360.162.520.300.325.340'], ['D12.776.930.155.200.200'], ['D12.776.260'], ['D12.776.260.257', 'D12.776.93... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of iodine-131 dose on the outcome of hyperthyroidism in children. | OBJECTIVES: Iodine-131 is an effective treatment for Graves' hyperthyroidism in children and adults. Yet the responses to treatment as related to iodine-131 dose in children are not well-defined. The objective of this study was to examine the relationship between the dose of iodine-131 in children with hyperthyroidism ... | ['Adolescent', 'Adult', 'Child', 'Dose-Response Relationship, Radiation', 'Female', 'Follow-Up Studies', 'Graves Disease', 'Humans', 'Hyperthyroidism', 'Hypothyroidism', 'Iodine Radioisotopes', 'Male', 'Radiotherapy Dosage', 'Thyroid Gland', 'Treatment Outcome'] | 12,671,107 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C11.675.349.500', 'C19.874.283.605', 'C19.874.397.370', 'C20.111.555'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Simple method for preparing poly(ethylene glycol)-surface-conjugated liposome-encapsulated hemoglobins: physicochemical properties, long-term storage stability, and their reactions with O2, CO, and NO. | During the last few decades, liposome-encapsulated hemoglobin (LEH) dispersions have been investigated for use as red blood cell (RBC) substitutes. However, the process for formulating LEHs is cumbersome, and the composition of the lipid mixture is often complex. This work investigates a simple approach to formulating ... | ['Animals', 'Blood Substitutes', 'Blood Transfusion', 'Capsules', 'Carbon Monoxide', 'Cattle', 'Chemical Phenomena', 'Hemoglobins', 'Humans', 'Kinetics', 'Liposomes', 'Methemoglobin', 'Nitric Oxide', 'Oxygen', 'Polyethylene Glycols', 'Surface Properties'] | 21,678,920 | [['B01.050'], ['D27.505.954.502.140', 'J01.637.087.249'], ['E02.095.135'], ['D26.255.150'], ['D01.200.250', 'D01.362.200', 'D01.650.550.250'], ['B01.050.150.900.649.313.500.380.271'], ['G02'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The RhoA effector mDia is induced during T cell activation and regulates actin polymerization and cell migration in T lymphocytes. | Regulation of actin polymerization is critical for many different functions of T lymphocytes, including cell migration. Here we show that the RhoA effector mDia is induced in vitro in activated PBL and is highly expressed in vivo in diseased tissue-infiltrating activated lymphocytes. mDia localizes at the leading edge ... | ['Actins', 'Carrier Proteins', 'Cell Adhesion', 'Cell Line, Transformed', 'Cell Migration Inhibition', 'Cell Movement', 'Cell Polarity', 'Cell Size', 'Cells, Cultured', 'Contractile Proteins', 'HeLa Cells', 'Humans', 'Integrins', 'Intracellular Signaling Peptides and Proteins', 'Jurkat Cells', 'Lymphocyte Activation', ... | 12,847,276 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D12.776.157'], ['G04.022'], ['A11.251.210.172'], ['G04.198.337'], ['G04.198', 'G07.568.500.180'], ['G04.250'], ['G04.325'], ['A11.251'], ['D12.776.210'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization and treatment of the liquid effluents from the anaerobic digestion of biogenic solid waste. | The process wastewater generated by the fermentation of biogenic fractions of solid waste (biowaste) is characterized by very specific composition features, which sets it apart from the well known categories of wastewater. Up to now, there is a definite lack of practical experience and know-how in the treatment of thos... | ['Anaerobiosis', 'Bioreactors', 'Fermentation', 'Nitrogen', 'Organic Chemicals', 'Refuse Disposal', 'Solubility', 'Waste Disposal, Fluid'] | 11,381,915 | [['G02.111.062', 'G03.078'], ['E07.115', 'J01.897.120.115'], ['G02.111.158.249', 'G03.191.249'], ['D01.268.604', 'D01.362.625'], ['D02'], ['N06.850.780.200.800.800.700', 'N06.850.860.510.900.600'], ['G02.805'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Modified TDx assay for cyclosporine and metabolites, for use with whole-blood samples. | A recently introduced fluorescence polarization immunoassay (FPIA) for determination of cyclosporine A in serum and plasma is discussed with regard to its use for whole-blood samples, with and without hemolysis before the assay. The performance characteristics of the modified method are highly satisfactory (within-run ... | ['Cyclosporins', 'Fluorescence Polarization', 'Hemolysis', 'Humans', 'Radioimmunoassay', 'Reagent Kits, Diagnostic', 'Temperature'] | 3,390,918 | [['D04.345.566.235', 'D12.644.641.235'], ['E05.196.712.516.600.390'], ['C23.550.403', 'G12.122.545'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['D27.505.259.875', 'D27.720.470.410.680', 'E07.720'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes. | Yeast cells contain a family of three monothiol glutaredoxins: Grx3, 4, and 5. Absence of Grx5 leads to constitutive oxidative damage, exacerbating that caused by external oxidants. Phenotypic defects associated with the absence of Grx5 are suppressed by overexpression of SSQ1 and ISA2, two genes involved in the synthe... | ['Amino Acid Sequence', 'Antifibrinolytic Agents', 'Blotting, Western', 'DNA, Complementary', 'Glutaredoxins', 'Iron', 'Iron-Sulfur Proteins', 'Mitochondria', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Mutation', 'Oxidation-Reduction', 'Oxidoreductases', 'Oxygen', 'Peptides', 'Plasmids', 'Protein Binding... | 11,950,925 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D27.505.519.421.500', 'D27.505.954.502.270.463.091'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D08.811.682.667.084'], ['D01.268.556.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Factor X activator from Vipera lebetina snake venom, molecular characterization and substrate specificity. | Our studies of the venom from the Levantine viper Vipera lebetina have demonstrated the existence of both coagulants and anticoagulants of the hemostatic system in the same venom. We showed that V. lebetina venom contains factor X activator (VLFXA) and factor V activator, fibrinolytic enzymes. VLFXA was separated by ge... | ['Chromatography, Gel', 'Chromatography, Ion Exchange', 'Cysteine Endopeptidases', 'Electrophoresis, Polyacrylamide Gel', 'Factor X', 'Humans', 'Isoelectric Focusing', 'Metalloendopeptidases', 'Molecular Weight', 'Neoplasm Proteins', 'Peptide Fragments', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization'... | 11,731,090 | [['E05.196.181.400.250'], ['E05.196.181.400.383'], ['D08.811.277.656.262.500', 'D08.811.277.656.300.200'], ['E05.196.401.402', 'E05.301.300.319'], ['D08.622.471', 'D12.776.124.125.400', 'D12.776.811.243.471', 'D23.119.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.401.663', 'E05.301.300.663'], ['D08.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Variation in amount of enzyme protein in natural populations. | Among strains of Drosophila melanogaster each derived from a single fertilized female taken from natural populations, there is variation in both alcohol dehydrogenase (ADH) activity and the amount of ADH protein. The correlation between ADH activity and number of molecules over all strains examined is 0.87 or 0.96 in l... | ['Alcohol Oxidoreductases', 'Catalysis', 'Drosophila melanogaster', 'Genetic Variation', 'Isoenzymes', 'Kinetics', 'Larva', 'Substrate Specificity'] | 98,165 | [['D08.811.682.047'], ['G02.130'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G05.365'], ['D08.811.348', 'D12.776.800.300'], ['G01.374.661', 'G02.111.490'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G02.111.835']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[An adult case of rhabdmyosarcoma of the urinary bladder]. | A 37-year-old man was referred to our department for investigation of grosshematuria. Ultrasonography and computed tomography of the abdomen showed a mass in the urinary bladder. Emergency transurethral resection was performed for the control of bleeding. The histopathological diagnosis was rhabdomyosarcoma of the urin... | ['Adult', 'Humans', 'Male', 'Rhabdomyosarcoma', 'Urinary Bladder Neoplasms'] | 23,328,166 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.590.550.660', 'C04.557.450.795.550.660'], ['C04.588.945.947.960', 'C12.758.820.968', 'C12.777.829.813', 'C13.351.937.820.945', 'C13.351.968.829.707']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Acute submaxillitis: Etiological data and etiological management. | OBJECTIVES: The objective of the present study was to test the hypothesis that acute submaxillitis involves salivary duct obstruction. Obstacle characteristics and treatment were analyzed.MATERIAL AND METHODS: Patients presenting with an episode of acute submaxillitis between 2009 and 2015 were retrospectively included... | ['Acute Disease', 'Female', 'Hospitals, University', 'Humans', 'Laryngoscopy', 'Male', 'Otolaryngology', 'Retrospective Studies', 'Salivary Gland Calculi', 'Sialography', 'Submandibular Gland Diseases', 'Treatment Outcome'] | 28,359,731 | [['C23.550.291.125'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.386.460', 'E01.370.388.250.525', 'E04.502.250.525', 'E04.580.373'], ['H02.403.810.526'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330... | ['Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Conjugative Plasmid Transfer in Xylella fastidiosa Is Dependent on tra | The insect-transmitted plant pathogen Xylella fastidiosa is capable of efficient horizontal gene transfer (HGT) and recombination. Natural transformation occurs at high rates in X. fastidiosa, but there also is evidence that certain strains of X. fastidiosa carry native plasmids equipped with transfer and mobilization ... | ['Conjugation, Genetic', 'Gene Transfer, Horizontal', 'Genes, Bacterial', 'Operon', 'Plasmids', 'Type IV Secretion Systems', 'Xylella'] | 28,808,128 | [['G05.728.200'], ['G05.728.390'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.360.340.024.686', 'G05.360.340.358.207.500'], ['G05.360.600'], ['D05.500.890.500.937'], ['B03.440.400.425.967.950', 'B03.660.250.915.950']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Patient-reported outcomes in urticarial vasculitis treated with omalizumab: case report. | BACKGROUND: Despite the current knowledge of UV, there is a lack of consensus among diagnostic criteria and management. In general, antihistamine therapy is regularly used for the symptomatic management of pruritus but does not control inflammation or alter the course of the disease. Monoclonal antibodies such as omali... | ['Anti-Allergic Agents', 'Chronic Disease', 'Female', 'Histamine H1 Antagonists, Non-Sedating', 'Humans', 'Middle Aged', 'Omalizumab', 'Patient Reported Outcome Measures', 'Pruritus', 'Recurrence', 'Urticaria', 'Vasculitis, Leukocytoclastic, Cutaneous'] | 30,359,231 | [['D27.505.954.016'], ['C23.550.291.500'], ['D27.505.519.625.375.425.400.500', 'D27.505.696.577.375.425.400.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D12.776.124.486.485.114.071.500', 'D12.776.124.486.485.114.224.060.844', 'D12.776.124.790.651.114.071.500', 'D12.776.124.790.651.114.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Detectable concentrations of Fas ligand in cerebrospinal fluid after severe head injury. | When the cell surface molecule Fas is triggered by its agonist Fas ligand the result is apoptosis of these cells and tissue destruction. To elucidate the pathophysiological relevance of Fas ligand in patients with cerebral oedema caused by trauma, we examined its concentrations in cerebrospinal fluid in 18 patients usi... | ['Adult', 'Apoptosis', 'Blood-Brain Barrier', 'Brain Edema', 'Brain Injuries', 'Cerebrovascular Circulation', 'Fas Ligand Protein', 'Humans', 'Intracranial Pressure', 'Ligands', 'Membrane Glycoproteins', 'Middle Aged', 'Solubility', 'fas Receptor'] | 9,413,263 | [['M01.060.116'], ['G04.146.954.035'], ['A07.035', 'A08.186.211.035'], ['C10.228.140.187'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['G09.330.100.159'], ['D12.644.276.374.750.249', 'D12.776.395.550.312', 'D12.776.467.374.750.249', 'D12.776.543.550.312', 'D23.529.374.750.249'], ['B01.050.150.900.649.3... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Parental history of diabetes in a population-based study. | OBJECTIVE: To evaluate the relative frequency of parental history of diabetes in a population-based study of younger- and older-onset groups of individuals with diabetes and a comparison group of individuals without diabetes.RESEARCH DESIGN AND METHODS: Study participants were queried about a family history of diabetes... | ['Adult', 'Age Factors', 'Age of Onset', 'Analysis of Variance', 'Cohort Studies', 'Diabetes Mellitus', 'Fathers', 'Female', 'Genomic Imprinting', 'Humans', 'Male', 'Middle Aged', 'Mothers', 'Nuclear Family', 'Prevalence', 'Wisconsin'] | 8,842,599 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C18.452.394.750', 'C19.246'], ['F01.829.263.500.320.100', 'I01.880... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
An injectable supramolecular hydrogel hybridized with silver nanoparticles for antibacterial application. | Silver nanoparticles (AgNPs) show long-lasting and broad-spectrum antibacterial activity. Herein, PEGylated AgNPs were prepared in situ by complexing AgNO3 with the random copolymer of poly(ethylene glycol) methyl ether methacrylate (PEGMA) and polyacrylic acid via electrostatic interaction followed by in situ reductio... | ['Anti-Bacterial Agents', 'Escherichia coli', 'HeLa Cells', 'Humans', 'Hydrogels', 'Injections', 'Materials Testing', 'Metal Nanoparticles', 'Polyethylene Glycols', 'Silver', 'Staphylococcus aureus', 'alpha-Cyclodextrins'] | 29,354,845 | [['D27.505.954.122.085'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.280.320.375', 'D26.255.165.320.375'], ['E02.319.267.530'], ['E05.570'], ['J01.637.512.600.500'], ['D02.033.455.250.700',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Causal inference from observational data. | Randomized controlled trials have long been considered the 'gold standard' for causal inference in clinical research. In the absence of randomized experiments, identification of reliable intervention points to improve oral health is often perceived as a challenge. But other fields of science, such as social science, ha... | ['Causality', 'Data Interpretation, Statistical', 'Dental Research', 'Humans', 'Observational Studies as Topic', 'Regression Analysis'] | 27,111,146 | [['N05.715.350.200', 'N06.850.490.625'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['H01.770.644.145.124', 'H02.163.090'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.250.500', 'N05.715.360.330.250.500', 'N06.850.520.450.250.500'], ['... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Does sleep duration, napping, and social jetlag predict hemoglobin A1c among college students with type 1 diabetes mellitus? | AIMS: The first aim examined the relationship between sleep behaviors (duration, napping, and social jetlag) and hemoglobin A1c (HbA1c) among emerging young adults (EYAs) with T1DM between 18 and 25 years old, who are living on a college campus. The second aim characterized the gender differences in glucose management,... | ['Adolescent', 'Adult', 'Blood Glucose', 'Cross-Sectional Studies', 'Diabetes Mellitus, Type 1', 'Female', 'Glycated Hemoglobin A', 'Humans', 'Male', 'Prognosis', 'Sleep', 'Sleep Wake Disorders', 'Social Behavior', 'Students', 'Surveys and Questionnaires', 'Time Factors', 'Young Adult'] | 30,641,174 | [['M01.060.057'], ['M01.060.116'], ['D09.947.875.359.448.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.31... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Basolateral K+ channel involvement in forskolin-activated chloride secretion in human colon. | 1. In this study we investigated the role of basolateral potassium transport in maintaining cAMP-activated chloride secretion in human colonic epithelium. 2. Ion transport was quantified in isolated human colonic epithelium using the short-circuit current technique. Basolateral potassium transport was studied using nys... | ["4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid", 'Biological Transport', 'Bumetanide', 'Calcium', 'Cell Membrane', 'Chlorides', 'Colforsin', 'Colon', 'Humans', 'In Vitro Techniques', 'Intestinal Mucosa', 'Kinetics', 'Membrane Potentials', 'Models, Biological', 'Potassium', 'Potassium Channels', 'Sodium', 'Tetraethy... | 10,432,355 | [['D02.455.426.559.389.150.700.200', 'D02.500.375.125', 'D02.886.250.125'], ['G03.143'], ['D02.065.884.150', 'D02.241.223.100.050.300.200', 'D02.455.426.559.389.127.020.452.500', 'D02.886.590.700.150'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.284.149'], ['D01.210.450.150', 'D01.248.497.158.215'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sperm morphology analysis using strict criteria as a prognostic factor in intrauterine insemination. | The objective of this study was to investigate the predictive value of Kruger's criteria for sperm morphology on intrauterine insemination (IUI) outcome. A total of 209 infertile patients underwent 244 IUI treatment cycles. These include 75 couples (80 cycles) with teratozoospermia and 134 couples (164 cycles) with une... | ['Adult', 'Female', 'Humans', 'Insemination, Artificial', 'Male', 'Pregnancy', 'Pregnancy Rate', 'Prognosis', 'Spermatozoa', 'Uterus'] | 12,270,024 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.875.800.937', 'E05.820.800.937', 'G08.686.784.363.492'], ['G08.686.784.769'], ['E05.318.308.985.775', 'G08.686.705', 'N01.224.935.849', 'N06.850.505.400.975.775', 'N06.850.520.308.985.775'], ['E01.789'], ['A05.360.490.890', 'A11.497.760'], ['A05.3... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Keratitis-ichthyosis-deafness (KID) syndrome. | A 21-year-old man presented with a life-long history of diffusely thickened skin with a grainy-to-ridged surface, verrucous perioral plaques with radial fissures, and diffuse palmoplantar keratoderma with a stippled appearance. These skin findings were accompanied by sensorineural hearing loss and keratoconjunctivitis,... | ['Deafness', 'Humans', 'Ichthyosis', 'Keratitis', 'Male', 'Syndrome', 'Young Adult'] | 19,891,919 | [['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.131.831.512', 'C16.614.492', 'C17.800.428.333', 'C17.800.804.512'], ['C11.204.564'], ['C23.550.288.500'], ['M01.060.116.815']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Influence of adynamic bone disease on responsiveness to recombinant human erythropoietin in peritoneal dialysis patients. | Adynamic bone disease (ABD) has an increasing prevalence in the dialysis population, more so in peritoneal dialysis patients. Anemia in patients with high turnover bone disease and high intact parathyroid hormone (iPTH) tends to be resistant to recombinant human erythropoietin (rHuEPO). The same problem may occur in pa... | ['Aged', 'Alkaline Phosphatase', 'Anemia', 'Chronic Kidney Disease-Mineral and Bone Disorder', 'Drug Resistance', 'Erythropoietin', 'Female', 'Ferritins', 'Hematocrit', 'Humans', 'Iron', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Parathyroid Hormone', 'Peritoneal Dialysis', 'Recombinant Proteins'] | 11,045,314 | [['M01.060.116.100'], ['D08.811.277.352.650.035'], ['C15.378.071'], ['C05.116.198.816.750', 'C12.777.419.080', 'C13.351.968.419.795', 'C18.452.104.816.750', 'C18.452.174.845.750', 'C18.654.521.500.133.770.734.750', 'C19.642.355.480.500'], ['G07.690.773.984'], ['D12.644.276.374.410.240.150', 'D12.776.395.240.150', 'D12.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Protein O-mannosylation deficiency increases LprG-associated lipoarabinomannan release by Mycobacterium tuberculosis and enhances the TLR2-associated inflammatory response. | Protein O-mannosylation is crucial for the biology of Mycobacterium tuberculosis but the key mannosylated protein(s) involved and its(their) underlying function(s) remain unknown. Here, we demonstrated that the M. tuberculosis mutant (Äpmt) deficient for protein O-mannosylation exhibits enhanced release of lipoarabinom... | ['Animals', 'Bacterial Proteins', 'Female', 'Gene Deletion', 'Glycosylation', 'Inflammation', 'Lipopolysaccharides', 'Mannose', 'Mice, Inbred BALB C', 'Mycobacterium smegmatis', 'Mycobacterium tuberculosis', 'Toll-Like Receptor 2', 'Virulence Factors'] | 28,801,649 | [['B01.050'], ['D12.776.097'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['C23.550.470'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500'], ['D09.947.875.359.588'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.99... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A comparison of the effects of substance P and shorter analogues on the synaptosomal ATPases activities in the rat brain. | The influence in vitro of SP and C-terminal fragments of analogues SP(5-11) (pyroGlu5, Tyr8); SP(6-11) (pyroGlu6, Tyr8); SP(6-11) (pyroGlu6, D-Phe7); SP(6-11) (pyroGlu6, D-Phe8) on the (Ca, Mg) and (Na, K) ATPases activities from synaptosomal membranes of cerebral cortex and hippocampus of rat brain were compared. The ... | ['Adenosine Triphosphatases', 'Animals', 'Ca(2+) Mg(2+)-ATPase', 'Calcium-Transporting ATPases', 'Cerebral Cortex', 'Hippocampus', 'Kinetics', 'Male', 'Rats', 'Rats, Inbred Strains', 'Sodium-Potassium-Exchanging ATPase', 'Structure-Activity Relationship', 'Substance P', 'Synaptosomes'] | 2,442,045 | [['D08.811.277.040.025'], ['B01.050'], ['D08.811.277.040.025.095'], ['D08.811.277.040.025.314.250', 'D12.776.157.530.450.250.500', 'D12.776.157.530.813.250', 'D12.776.543.585.450.250.500', 'D12.776.543.585.813.250'], ['A08.186.211.200.885.287.500'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['G01.374.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease. | Evidence of reduced blood-brain barrier (BBB) integrity preceding other Alzheimer's disease (AD) pathology provides a strong link between cerebrovascular angiopathy and AD. However, the "Vascular hypothesis", holds that BBB leakiness in AD is likely due to hypoxia and neuroinflammation leading to vascular deterioration... | ['Aging', 'Alzheimer Disease', 'Amyloid', 'Animals', 'Apoptosis', 'Blood-Brain Barrier', 'Brain', 'Female', 'Humans', 'Male', 'Mice', 'Mice, Transgenic', 'Microvessels', 'Neovascularization, Pathologic', 'Permeability', 'Signal Transduction', 'Tight Junctions'] | 21,909,359 | [['G07.345.124'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D05.500.049', 'D12.776.049'], ['B01.050'], ['G04.146.954.035'], ['A07.035', 'A08.186.211.035'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.0... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Reduced glutathione inhibits beta-NAD+-activated non-selective cation currents in the CRI-G1 rat insulin-secreting cell line. | 1. Whole-cell voltage-clamp recordings were used to study the characteristics of a non-selective cation current, activated by intracellular beta-NAD+, present in CRI-G1 insulin-secreting cells. The monovalent cations Na+, K+ and Cs+ were equally permeant through this channel. 2. The magnitude of the beta-NAD+ current w... | ['Animals', 'Cations', 'Cell Line', 'Cesium', 'Glutathione', 'Hypoglycemic Agents', 'Insulin', 'Insulin Secretion', 'Ion Channel Gating', 'NAD', 'Oligopeptides', 'Patch-Clamp Techniques', 'Rats', 'Tolbutamide'] | 9,831,715 | [['B01.050'], ['D01.248.497.300'], ['A11.251.210'], ['D01.268.549.125', 'D01.268.556.165', 'D01.552.528.160', 'D01.552.544.165'], ['D12.644.456.448'], ['D27.505.696.422'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['G03.442', 'G07.475'], ['G02.111.820.400', 'G04.835.400', 'G07.265.625'], ['D03.633... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Normal Heart Rate Variability in Colchicine-Resistant Familial Mediterranean Fever Patients. | BACKGROUND: The relationship between autonomic nervous system (ANS) dysfunction and familial Mediterranean fever (FMF) is controversial. We recently reported normal heart rate variability (HRV), suggestive of normal ANS, in patients with uncomplicated FMF.OBJECTIVES: To evaluate ANS function in colchicine non-responder... | ['Adult', 'Autonomic Nervous System', 'Case-Control Studies', 'Colchicine', 'Confounding Factors, Epidemiologic', 'Drug Resistance', 'Electrocardiography', 'Familial Mediterranean Fever', 'Female', 'Heart', 'Heart Rate', 'Humans', 'Israel', 'Male', 'Middle Aged', 'Reference Values', 'Secondary Prevention'] | 26,137,658 | [['M01.060.116'], ['A08.800.050'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D03.132.225'], ['N05.715.350.240', 'N06.850.490.718'], ['G07.690.773.984'], ['E01.370.370.380.240', 'E01.370.405.240'], ['C16.320.382.625'], ['A07.541'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Multiple drilling combined with simvastatin versus multiple drilling alone for the treatment of avascular osteonecrosis of the femoral head: 3-year follow-up study. | BACKGROUND: Multiple small drilling for core decompression is widely used to preserve the femoral head in patients with avascular necrosis of the femoral head (ANFH). Nevertheless, the clinical outcome remains controversial. Simvastatin has been demonstrated to promote bone formation and reduce bone adsorption. The pur... | ['Adult', 'Body Mass Index', 'Combined Modality Therapy', 'Decompression, Surgical', 'Disease Progression', 'Female', 'Femur Head', 'Femur Head Necrosis', 'Follow-Up Studies', 'Hip', 'Humans', 'Hydroxymethylglutaryl-CoA Reductase Inhibitors', 'Male', 'Middle Aged', 'Osteogenesis', 'Prognosis', 'Radiography', 'Reoperati... | 27,528,281 | [['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E02.186'], ['E04.188'], ['C23.550.291.656'], ['A02.835.232.043.150.343'], ['C05.116.852.175', 'C23.550.717.732.368'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tumor origin and CD20 expression in posttransplant lymphoproliferative disorder occurring in solid organ transplant recipients: implications for immune-based therapy. | BACKGROUND: Posttransplant lymphoproliferative disorder (PTLD) is a potentially fatal complication of transplantation for which new therapies are being explored, including cytotoxic T-cell infusion and anti-CD20 antibody. Whether the PTLD is of donor cell or recipient cell origin influences the type of cytotoxic T-cell... | ['Antigens, CD', 'Antigens, CD20', 'Chromosome Mapping', 'Epstein-Barr Virus Infections', 'Follow-Up Studies', 'Heart Transplantation', 'Herpesvirus 4, Human', 'Humans', 'Immunosuppression', 'Kidney Transplantation', 'Lung Transplantation', 'Lymphoproliferative Disorders', 'Microsatellite Repeats', 'Neoplasms', 'T-Lymp... | 14,508,361 | [['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.035.120', 'D23.050.301.264.051.120', 'D23.101.100.110.120', 'D23.101.100.150.120'], ['E05.393.183'], ['C01.925.256.466.313', 'C01.925.928.313'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.100.376.475', '... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Tularaemia in European Brown Hares (Lepus europaeus) and Mountain Hares (Lepus timidus) Characterized by Histopathology and Immunohistochemistry: Organ Lesions and Suggestions of Routes of Infection and Shedding. | Tularaemia is an emerging zoonotic infectious disease caused by the bacterium Francisella tularensis. In Sweden, hares are considered to be key species in the epidemiology of tularaemia. The aim of this study was to characterize the pathology of natural tularaemia infection in European brown hares (EBHs) (Lepus europae... | ['Animals', 'Hares', 'Tularemia', 'Zoonoses'] | 28,942,292 | [['B01.050'], ['B01.050.150.900.649.313.968.400'], ['C01.150.252.400.900', 'C01.920.930.943'], ['C01.973', 'C22.969']] | ['Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Studies of the subunit structure of choleragen. | The two choleragen protein constituents were isolated and characterized. Protein I has a molecular weight of approximately 54000. It consists of subunits of approximate molecular weight 10000. Protein II with molecular weight of approximately 32000 is cleaved by 2-mercaptoethanol into two fragments, protein II1 (N-term... | ['Amino Acids', 'Bacterial Proteins', 'Immunodiffusion', 'Macromolecular Substances', 'Mercaptoethanol', 'Molecular Weight', 'Toxins, Biological', 'Vibrio cholerae'] | 809,284 | [['D12.125'], ['D12.776.097'], ['E01.370.225.812.735.645.350', 'E05.200.812.735.645.350', 'E05.478.594.760.645.350', 'E05.478.605.492.350'], ['D05'], ['D02.033.375.534', 'D02.886.489.409'], ['G02.494'], ['D23.946'], ['B03.440.450.900.859.225', 'B03.660.250.830.830.100']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Age trends in pre-cancerous and cancerous lesions of the uterine cervix in a cytology screening programme: what should be the target age group for a major thrust of screening in resource-limited settings? | OBJECTIVE: To identify the target age group where screening efforts may be concentrated in order to reduce the incidence of cervical cancer in resource-limited countries.STUDY DESIGN: The results of cyto-screening in a hospital-based screening programme for early detection of cervical cancer were analysed retrospective... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Cervical Intraepithelial Neoplasia', 'Economics, Hospital', 'Female', 'Health Care Rationing', 'Humans', 'India', 'Mass Screening', 'Middle Aged', 'Precancerous Conditions', 'Uterine Cervical Neoplasms', 'Vaginal Smears'] | 17,681,014 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.240.250'], ['N03.219.262'], ['I01.261.750.500', 'N03.349.270', 'N05.300.430.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['E01.370.500', 'E05.318.308.980.438.580', 'N... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Risk Perceptions of Wastewater Use for Urban Agriculture in Accra, Ghana. | Poor food hygiene is a significant risk to public health globally, but especially in low and middle-income countries where access to sanitation, and general hygiene remain poor. Food hygiene becomes even more pertinent when untreated, or poorly treated wastewater is used in agriculture. In such circumstances the WHO re... | ['Agriculture', 'Awareness', 'Diet', 'Ghana', 'Humans', 'Risk Assessment', 'Urbanization', 'Waste Water'] | 26,978,778 | [['J01.040'], ['F02.463.188.150'], ['G07.203.650.240'], ['Z01.058.290.190.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['I01.880.853.400.726'], ['D20.944.932', 'N06.850.460.710.865... | ['Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Dr... | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 |
Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations. | Nucleated polymerisation processes are involved in many growth phenomena in nature, including the formation of cytoskeletal filaments and the assembly of sickle hemoglobin and amyloid fibrils. Closed form rate equations have, however, been challenging to derive for these growth phenomena in cases where secondary nuclea... | ['Biopolymers', 'Crystallization', 'Models, Theoretical', 'Polymerization'] | 21,842,955 | [['D05.750.078', 'D25.720.099', 'J01.637.051.720.099'], ['E05.196.300', 'G02.171'], ['E05.599'], ['G02.750']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Post-transcriptional inhibition of ornithine decarboxylase induction by zinc in a difluoromethylornithine resistant cell line. | Addition of Zn2+ to cell medium inhibited the induction of ornithine decarboxylase (ODC) activity in ODC overproducing L1210-DFMOr cells. A significant effect was observed at a concentration as low as 0.01 mM, however, a more marked inhibition was caused by the addition of 0.1 mM Zn2+. The inhibition of the induction o... | ['Animals', 'Cell Line', 'Drug Resistance', 'Eflornithine', 'Enzyme Induction', 'Mice', 'Ornithine Decarboxylase', 'RNA, Messenger', 'Transcription, Genetic', 'Zinc'] | 7,918,572 | [['B01.050'], ['A11.251.210'], ['G07.690.773.984'], ['D12.125.068.665.340', 'D12.125.095.765.340'], ['G05.308.320.200'], ['B01.050.150.900.649.313.992.635.505.500'], ['D08.811.520.224.125.425'], ['D13.444.735.544'], ['G02.111.873', 'G05.297.700'], ['D01.268.556.940', 'D01.268.956.906', 'D01.552.544.940']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High-frequency jet ventilation during oleic-acid induced pulmonary oedema. | In oleic acid-induced pulmonary oedema (OAPO) sequential intrapulmonary fluid accumulation occurs leading to different expiratory flow pattern in dependent lung regions. The potential effects on efficacy of high-frequency jet ventilation (HFJV, f = 3 Hz, I: E = 0.43, FiO2 = 0.4) were studied and compared with continuou... | ['Animals', 'Disease Models, Animal', 'Dogs', 'Hemodynamics', 'High-Frequency Jet Ventilation', 'Lung Compliance', 'Oleic Acids', 'Positive-Pressure Respiration', 'Pulmonary Edema', 'Pulmonary Gas Exchange'] | 2,654,240 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.750.250.216.200'], ['G09.330.380'], ['E02.041.625.508.510', 'E02.880.820.508.510'], ['E01.370.386.700.475', 'G09.772.540'], ['D10.251.355.325.600'], ['E02.041.625.790', 'E02.880.820.790'], ['C08.381.742'], ['E01.370.386.700.650', 'G0... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Loving and Leaving Public Health: Predictors of Intentions to Quit Among State Health Agency Workers. | CONTEXT: State health agencies play a critical role in protecting and promoting the health and well-being of the people they serve. To be effective, they must maintain a highly skilled, diverse workforce of sufficient size and with proper training.OBJECTIVE: The goal of this study was to examine demographics, job and w... | ['Adult', 'Aged', 'Cross-Sectional Studies', 'Female', 'Humans', 'Intention', 'Job Satisfaction', 'Male', 'Middle Aged', 'Personnel Turnover', 'Public Health', 'State Government', 'Workforce'] | 26,422,500 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.650', 'F02.463.306'], ['F02.784.692.425'], ['M01.060.116.630'], ['N04.452.677.680'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['I01.409.775',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Protective role of Ficus deltoidea against BPA-induced impairments of the follicular development, estrous cycle, gonadotropin and sex steroid hormones level of prepubertal rats. | Ficus deltoidea is one of the well-known medicinal plants in Malaysia that is traditionally used by the Malay community to treat various ailments and for maintenance of female reproductive health. The objective of this study is to evaluate the potential protective roles of Ficus deltoidea against BPA-induced toxicity o... | ['Animals', 'Benzhydryl Compounds', 'Estrogens, Non-Steroidal', 'Estrous Cycle', 'Female', 'Ficus', 'Hormones', 'Ovarian Follicle', 'Phenols', 'Plant Extracts', 'Protective Agents', 'Rats, Sprague-Dawley', 'Sexual Maturation'] | 30,477,542 | [['B01.050'], ['D02.455.426.559.389.115'], ['D27.505.696.399.472.277.540'], ['G08.686.195'], ['B01.650.940.800.575.912.250.859.937.406.500'], ['D06.472', 'D27.505.696.399.472'], ['A05.360.319.114.630.535', 'A06.300.312.497.535'], ['D02.455.426.559.389.657'], ['D20.215.784.500', 'D26.667'], ['D27.505.696.706', 'D27.720.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of Chemerin and Its Receptors in the Porcine Hypothalamus and Plasma Chemerin Levels during the Oestrous Cycle and Early Pregnancy. | Chemerin (CHEM) may act as an important link integrating energy homeostasis and reproductive functions of females, and its actions are mediated by three receptors: chemokine-like receptor 1 (CMKLR1), G protein-coupled receptor 1 (GPR1), and C-C motif chemokine receptor-like 2 (CCRL2). The aim of the current study was t... | ['Animals', 'Chemokines', 'Estrous Cycle', 'Female', 'Gene Expression', 'Gonadotropin-Releasing Hormone', 'Hypothalamus', 'Pregnancy', 'Receptors, Chemokine', 'Swine'] | 31,404,950 | [['B01.050'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300', 'D23.469.200', 'D23.529.374.200'], ['G08.686.195'], ['G05.297'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['A08.186.211.180.497', 'A08.186.211.200.317.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Glomerular filtration rate during lithium therapy. A longitudinal study. | In order to investigate the side effect of lithium on renal function the glomerular filtration rate (GFR) was measured before (to) and after a mean of 16.5 months (t1) (range 12-25 months) lithium treatment in 13 consecutive patients aged 32-67 years (mean age 46 years). The patients had a normal renal function before ... | ['Adult', 'Aged', 'Creatinine', 'Female', 'Glomerular Filtration Rate', 'Humans', 'Kidney', 'Lithium', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Time Factors'] | 6,496,147 | [['M01.060.116'], ['M01.060.116.100'], ['D03.383.129.308.207'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['D01.268.549.450', 'D01.268.557.290', 'D01.552.528.480', 'D01.552.547.290'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Immunohistochemical detection of somatostatin receptor subtypes sst1 and sst2A in human somatostatin receptor positive tumors. | Although in situ hybridization has been used to examine the distribution of messenger RNA for somatostatin receptor subtypes (sst) in human tumors, the cellular localization of sst1 and sst2A receptors has not been reported. In this study, we describe the cellular localization of human sst1 and sst2A receptor proteins ... | ['Adrenal Gland Neoplasms', 'Carcinoid Tumor', 'Carcinoma, Renal Cell', 'Gastrinoma', 'Glycosylation', 'Humans', 'Immunoblotting', 'Immunohistochemistry', 'Intestinal Neoplasms', 'Neoplasms', 'Pancreatic Neoplasms', 'Pheochromocytoma', 'RNA, Messenger', 'Receptors, Somatostatin'] | 10,022,452 | [['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['C04.557.465.625.650.200', 'C04.557.470.200.025.200', 'C04.557.580.625.650.200'], ['C04.557.470.200.025.390', 'C04.588.945.947.535.160', 'C12.758.820.750.160', 'C12.777.419.473.160', 'C13.351.937.820.535.160', 'C13.351.968.419.473.160'], ['C04.557.470.200.025.290.500... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Tuberculous Spondylitis - Diagnosis and Management]. | Tuberculous Spondylitis - Diagnosis and Management Abstract. Despite a decreasing incidence of tuberculosis (TB) over the last decades in Switzerland, the frequency of newly diagnosed tuberculous spondylitis has remained stable. It occurs most frequently in old, immunocompromised persons and/or persons who have moved t... | ['Humans', 'Spondylitis', 'Switzerland', 'Tuberculosis, Spinal'] | 32,752,962 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.160.762', 'C05.116.165.762', 'C05.116.900.853'], ['Z01.542.883'], ['C01.150.252.410.040.552.846.843.722', 'C01.160.886.722', 'C05.116.165.886.722', 'C05.116.900.853.850']] | ['Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
PEDS: developmental milestones--an accurate brief tool for surveillance and screening. | About 16% of children have developmental-behavioral disabilities but less than one-third of the children are detected by their health care providers, probably because of the use of informal milestones checklists. The goal of this study is to determine the reliability, validity, accuracy, and utility of a new tool, PEDS... | ['Child', 'Child, Preschool', 'Developmental Disabilities', 'Health Status Indicators', 'Humans', 'Infant', 'Infant, Newborn', 'Mass Screening', 'Neonatal Screening', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Task Performance and Analysis'] | 18,057,141 | [['M01.060.406'], ['M01.060.406.448'], ['F03.625.421'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Note on Kurzia (Kurzia) latissima (Kurz, 1875) (Branchiopoda: Anomopoda: Chydoridae) from India. | Members of the chydorid genus Kurzia Dybowski & Grochowski, 1894 (Branchiopoda: Anomopoda) are typically known from the Holarctic and the Neotropics (Rajapaska & Fernando 1986; Hudec 2000; Elmoor-Loureiro 2002; Kotov, 2004). One representative of the sub genus Kurzia, Kurzia (Kurzia) latissima (Kurz 1875) has been repo... | ['Animal Distribution', 'Animals', 'Crustacea', 'Female', 'India', 'Species Specificity'] | 26,249,955 | [['F01.145.113.069', 'G16.049'], ['B01.050'], ['B01.050.500.131.365'], ['Z01.252.245.393'], ['G16.824']] | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
[Effect of aortic clamping on heart function in elective operation of the abdominal aorta: immediate effects of coronary revascularization]. | Infrarenal aortic cross-clamping required during surgical treatment of abdominal aortic aneurysm is generally well tolerated but can be occasionally associated with severe cardiac and haemodynamic disturbances, particularly in patients suffering from coronary artery disease. We compared the haemodynamic changes and the... | ['Aged', 'Aortic Aneurysm, Abdominal', 'Blood Pressure', 'Combined Modality Therapy', 'Coronary Artery Bypass', 'Coronary Disease', 'Female', 'Heart Rate', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Myocardial Ischemia'] | 8,376,152 | [['M01.060.116.100'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E02.186'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['C14.280.647.250', 'C14.907.585.250'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G09.330.380'], ['B01.050.150.900.649... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
What language says about the psychology of events. | Despite the variety of verb meanings, linguistic research on their syntax and semantics has shown that they can be categorized into a finite and surprisingly small number of event types. More recently, research in the psycholinguistics of language acquisition and processing has emphasized the relevance of event type. T... | ['Humans', 'Language', 'Life Change Events', 'Psycholinguistics', 'Psychology', 'Vocabulary'] | 16,460,993 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.209.399', 'L01.559'], ['F01.829.458.410'], ['F02.694', 'F04.096.586', 'L01.559.598.628'], ['F04.096.628'], ['L01.559.598.901']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Nucleoside-amino acid conjugates: An alternative route to the design of ribonuclease A inhibitors. | Nucleoside-amino acid conjugates have been employed to inhibit the ribonucleolytic activity of ribonuclease A (RNase A) and affect the protonation/deprotonation equilibrium of its active site histidine residues. Agarose gel and precipitation assays indicate inhibition of RNase A activity by these molecules with a possi... | ['Amino Acids', 'Animals', 'Cattle', 'Hydrogen Bonding', 'Kinetics', 'Models, Molecular', 'Nucleosides', 'Pancreas', 'Protein Binding', 'Protein Conformation', 'Ribonuclease, Pancreatic'] | 19,540,766 | [['D12.125'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G02.282'], ['G01.374.661', 'G02.111.490'], ['E05.599.595'], ['D09.408.595', 'D13.570'], ['A03.734'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709'], ['D08.811.277.352.355.350.715', 'D08.811.277.352.700.350.715']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sperm chymotrypsin-like enzymes of different inhibitor-susceptibility as lysins in ascidians. | Inhibitory effects of three peptidyl phenylalaninals on fertilization and on chymotrypsin-like enzyme activity of sperm in three species of ascidians were examined. The results suggest that a sperm chymotrypsin-like enzyme is indispensable for the fertilization in each of the ascidians, and that these enzymes have diff... | ['Animals', 'Anti-Bacterial Agents', 'Chymotrypsin', 'Enzyme Inhibitors', 'Fertilization', 'Leupeptins', 'Male', 'Oligopeptides', 'Peptides', 'Spermatozoa', 'Urochordata'] | 3,622,736 | [['B01.050'], ['D27.505.954.122.085'], ['D08.811.277.656.300.760.176', 'D08.811.277.656.959.350.176'], ['D27.505.519.389'], ['G08.686.784.277'], ['D12.644.456.580'], ['D12.644.456'], ['D12.644'], ['A05.360.490.890', 'A11.497.760'], ['B01.050.150.200.727', 'B01.050.500.272.727']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treatment of the acute migraine attack--current status. | The main treatment of the acute migraine attack remains sleep, sedation, an anti-nauseant and analgesics, and in some patients 1 or 2 mg of ergotamine tartrate. Drugs containing large amounts of caffeine should not be used. Absorption of drugs may be impaired in a migraine attack. Metoclopramide is probably the anti-em... | ['Acetaminophen', 'Aspirin', 'Drug Therapy, Combination', 'Ergotamine', 'Ergotamines', 'Humans', 'Metoclopramide', 'Migraine Disorders'] | 6,406,072 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['D02.455.426.559.389.657.410.595.176'], ['E02.319.310'], ['D03.132.327.412.400', 'D03.633.400.562.500'], ['D03.132.327.412', 'D03.633.400.562'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.277.573', 'D02.241.223.100.050.500.647', 'D02.241.223.100.100.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of cervical sympathetic trunk transection on renal sympathetic nerve activity in rats. | Stellate ganglion blockade (SGB) with a local anesthetic increases muscle sympathetic nerve activity in the tibial nerve in humans. However, whether this sympathetic excitation in the tibial nerve is due to a sympathetic blockade in the neck itself, or due to infiltration of a local anesthetic to adjacent nerves includ... | ['Action Potentials', 'Adaptation, Physiological', 'Animals', 'Baroreflex', 'Blood Pressure', 'Ganglia, Sympathetic', 'Ganglionectomy', 'Heart Rate', 'Kidney', 'Male', 'Muscle, Skeletal', 'Nitroprusside', 'Rats', 'Rats, Sprague-Dawley', 'Tibial Nerve', 'Time Factors', 'Vasodilator Agents'] | 18,198,983 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['G07.025', 'G16.012.500'], ['B01.050'], ['G09.330.380.057', 'G11.561.731.063'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A08.340.315.350', 'A08.800.050.300.300', 'A08.800.050.800.300'], ['E04.525.210.105.800.380'], ['E01.370.600.875.500', 'G09.330.380.500'],... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Discovery of mammalian hosts to Gnathostoma nipponicum larvae and prevalence of the larvae in rodents and insectivores. | From September 1993 to November 1995, to clarify the natural infection of Gnathostoma nipponicum (G.n.) larvae in small wild mammals, a total of 313 animals consisted of three species of rodents and two species of insectivores, collected from an endemic area of this nematode in Aomori Prefecture, were investigated. Two... | ['Animals', 'Arvicolinae', 'Gnathostoma', 'Insectivora', 'Japan', 'Larva', 'Muridae', 'Prevalence', 'Rats', 'Rodent Diseases', 'Rodentia', 'Spirurida Infections'] | 8,898,280 | [['B01.050'], ['B01.050.150.900.649.313.992.635.075'], ['B01.050.500.500.294.400.937.700.722.375'], ['B01.050.150.900.649.313.961'], ['Z01.252.474.463', 'Z01.639.595'], ['B05.500.500', 'G07.345.500.550.500.500'], ['B01.050.150.900.649.313.992.635'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.97... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Radiologic imaging of osteosarcoma: role in planning surgical treatment. | We reviewed radiographic studies of 50 central osteosarcomas to assess their accuracy and contributions to surgical treatment planning. Accurate anatomic delineation was especially important when limb-sparing tumor resection was considered. The plain roentgenograms yielded most of the diagnostic information, and often ... | ['Adolescent', 'Adult', 'Aged', 'Angiography', 'Bone Neoplasms', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Middle Aged', 'Osteosarcoma', 'Patient Care Planning', 'Radionuclide Imaging', 'Tomography, X-Ray Computed'] | 6,579,671 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.350.700.060', 'E01.370.370.050'], ['C04.588.149', 'C05.116.231'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.450.565.575.650', 'C04.557.450.795.620'], ['N04.590.233.624'], ['E01.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Exploring new technologies to facilitate laparoscopic surgery: creating intestinal anastomoses without sutures or staples, using a radio-frequency-energy-driven bipolar fusion device. | INTRODUCTION: Intestinal anastomotic healing requires apposition of the collagen containing submucosal layers of the opposing intestinal walls, which is traditionally achieved by staples or sutures. Recently, a feedback-controlled bipolar sealing system (LigaSure) has been successfully introduced to seal and transect v... | ['Anastomosis, Surgical', 'Animals', 'Disease Models, Animal', 'Electrocoagulation', 'Equipment Design', 'Intestines', 'Laparoscopy', 'Sus scrofa', 'Suture Techniques', 'Treatment Outcome'] | 17,514,393 | [['E04.035'], ['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.154.402', 'E04.014.170.402'], ['E05.320'], ['A03.556.124'], ['E01.370.388.250.520', 'E04.502.250.520'], ['B01.050.150.900.649.313.500.880.399'], ['E04.987.775'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Clinical routine implantation of a dual chamber pacemaker system designed for safe use with MRI: a single center, retrospective study on lead performance of Medtronic lead 5086MRI in comparison to Medtronic leads 4592-53 and 4092-58. | AIMS: We report our experience concerning lead performance and re-surgery rate of the Medtronic EnRhythm MRI SureScan pacemaker system (MRI-PM) in comparison to standard pacemaker (PM) systems and leads used at our institution.METHODS: All patients (except patients with transvenous left ventricular leads) with successf... | ['Aged', 'Austria', 'Burns', 'Comorbidity', 'Electrodes, Implanted', 'Equipment Design', 'Equipment Failure', 'Equipment Failure Analysis', 'Female', 'Heart Failure', 'Humans', 'Incidence', 'Magnetic Resonance Imaging', 'Male', 'Pacemaker, Artificial', 'Prosthesis Implantation', 'Reoperation', 'Retrospective Studies', ... | 22,127,540 | [['M01.060.116.100'], ['Z01.542.088'], ['C26.200'], ['N05.715.350.225', 'N06.850.490.687'], ['E07.305.250.319', 'E07.695.202'], ['E05.320'], ['E05.325'], ['E05.325.192'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', '... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Sympathetic ophthalmia caused by ocular penetration with endophthalmitis]. | PURPOSE: To summarize the clinical features, diagnosis and treatment of sympathetic ophthalmia caused by ocular penetration with endophthalmitis.METHODS: Retrospective analysis was done on clinical data of 3 cases of sympathetic ophthalmia with ocular penetration and endophthalmitis.RESULTS: 5,253 cases of ocular penet... | ['Adult', 'Autoimmune Diseases', 'Endophthalmitis', 'Eye Injuries, Penetrating', 'Female', 'Fluorescein Angiography', 'Humans', 'Male', 'Middle Aged', 'Ophthalmia, Sympathetic', 'Retrospective Studies'] | 12,870,337 | [['M01.060.116'], ['C20.111'], ['C01.375.265', 'C11.294.265'], ['C10.900.300.284.250.270', 'C26.915.300.425.250.270', 'C26.986.450'], ['E01.370.370.050.350', 'E01.370.380.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C11.941.879.780.500', 'C20.111.709'], ['E05.318.372.500.500.500', 'E05... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ultra-pure polymerized bovine hemoglobin blood substitute: effects on the coronary circulation. | The effects of stroma-free hemoglobin (SFHgb) on the coronary circulation remain unclear. An intact canine model utilizing intracoronary adenosine to abolish the confounding effect of autoregulation was used to study maximal myocardial oxygen delivery during progressive hemodilution with polymerized bovine SFHgb. The c... | ['Animals', 'Blood Substitutes', 'Cattle', 'Coronary Circulation', 'Dogs', 'Hemodilution', 'Hemoglobins', 'Oxygen', 'Vasoconstriction'] | 1,391,493 | [['B01.050'], ['D27.505.954.502.140', 'J01.637.087.249'], ['B01.050.150.900.649.313.500.380.271'], ['G09.330.100.324'], ['B01.050.150.900.649.313.750.250.216.200'], ['E02.514'], ['D12.776.124.400', 'D12.776.422.316.762'], ['D01.268.185.550', 'D01.362.670'], ['G09.330.380.925']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Hypertension in a black population: prevalence and biosocial determinants of high blood pressure in a group of urban Nigerians. | AIMS: To define the prevalence of hypertension, a major cause of morbidity and mortality in blacks, and related biosocial factors in an urban African population group.METHODS: The setting was that of a civil service population in Ibadan, a major city in Southwestern Nigeria. Nine hundred and ninety-eight civil servants... | ['Adult', 'African Continental Ancestry Group', 'Aged', 'Anthropometry', 'Blood Glucose', 'Blood Pressure', 'Female', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Nigeria', 'Obesity', 'Prevalence', 'Sex Distribution', 'Socioeconomic Factors', 'Urban Population'] | 10,805,050 | [['M01.060.116'], ['M01.686.508.100'], ['M01.060.116.100'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['D09.947.875.359.448.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.116.630'], ['Z01.058.290.190.565'], ['C18.654.726.500', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Enhancing biodegradability of priority substances (pesticides) by solar photo-Fenton. | In this paper, we present the photo-Fenton treatment in a solar pilot-plant scale of several EU priority hazardous substances (Alachlor, Atrazine, Chlorfenvinphos, Diuron and Isoproturon) dissolved in water. The results have been evaluated not only from the point of view of contaminant disappearance and mineralisation,... | ['Acetamides', 'Atrazine', 'Biodegradation, Environmental', 'Bioreactors', 'Carbon', 'Chlorfenvinphos', 'Diuron', 'Herbicides', 'Hydrogen Peroxide', 'Insecticides', 'Iron', 'Molecular Structure', 'Phenylurea Compounds', 'Photochemistry', 'Sunlight', 'Water', 'Water Purification'] | 16,469,356 | [['D02.065.064', 'D02.241.081.018.110'], ['D03.383.931.247'], ['N06.230.080.600.500', 'N06.850.460.375.500'], ['E07.115', 'J01.897.120.115'], ['D01.268.150'], ['D02.705.400.120'], ['D02.065.950.681.397', 'D02.455.426.559.389.703.397'], ['D27.720.031.700.366', 'D27.888.723.366'], ['D01.248.497.158.685.750.424', 'D01.339... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Examination of cultural knowledge and provider sensitivity in nurse managed health centers. | It is important to examine empirical evidence of cultural competence among health care providers and to understand how it is assessed from an organizational context. There is a dearth of information about these concepts. Given its relevance to caring for diverse patient populations, the purpose of this paper is to pres... | ['Adult', 'Community Health Centers', 'Community Health Nursing', 'Cultural Competency', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', "Nurse's Role", 'Nurse-Patient Relations', 'Philosophy, Nursing', "Practice Patterns, Nurses'", 'United States', 'Young Adult'] | 25,011,210 | [['M01.060.116'], ['N02.278.035.128'], ['H02.478.676.150', 'N02.421.143.150'], ['I01.880.853.100.364'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.829.316.616.625.450', 'N05.300.100.337'], ['F01.829.401.650.600', 'N05.300.660.560'], ['K01.752.712'... | ['Named Groups [M]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
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