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Analysis of cytokine production by inflammatory mouse macrophages at the single-cell level: selective impairment of IL-12 induction in Leishmania-infected cells. | Intracellular staining for cytokines and parasites, combined with two-color flow cytometric analyses, were used to examine the frequencies of IL-12-, TNF-alpha- and IL-6-producing macrophages in response to Leishmania major infection and/or activation with IFN-gamma/lipopolysaccharide (LPS). Inflammatory macrophages we... | ['Animals', 'Female', 'Inflammation', 'Interleukin-12', 'Interleukin-6', 'Leishmania major', 'Leishmaniasis, Cutaneous', 'Macrophages', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C3H', 'Mice, Inbred C57BL', 'Mice, Inbred CBA', 'Tumor Necrosis Factor-alpha'] | 9,565,379 | [['B01.050'], ['C23.550.470'], ['D12.644.276.374.465.512', 'D12.776.467.374.465.512', 'D23.529.374.465.512'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['B01.268.475.868.488.405'], ['C01.610.752.300.500.400', 'C01.610.858.560.400', 'C01.920.813.400', 'C17.800.838.775.560.400'], ['A1... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chemically induced aneuploidy in mammalian cells in culture. | Our objectives were to assess whether there exist useful aneuploidy tests in vitro, to identify chemicals that showed potential for mitotic aneuploidy induction, and to recommend some features of suitable protocols for such testing. From over 100 papers we selected 24 for review. The acceptable studies examined hyperdi... | ['Aneuploidy', 'Animals', 'Biotransformation', 'Cell Line', 'Cells, Cultured', 'Crosses, Genetic', 'Evaluation Studies as Topic', 'Humans', 'Hydrogen-Ion Concentration', 'Kinetics', 'Metaphase', 'Mutagenicity Tests', 'Mutagens', 'Temperature'] | 3,941,674 | [['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['B01.050'], ['G03.171', 'G03.787.225', 'G07.690.725.225'], ['A11.251.210'], ['A11.251'], ['E05.393.281'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['G01.374.661', 'G02.111.490'], ['G04.144.220.220.687.625',... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Thalamocortical Innervation Pattern in Mouse Auditory and Visual Cortex: Laminar and Cell-Type Specificity. | Despite many previous studies, the functional innervation pattern of thalamic axons and their target specificity remains to be investigated thoroughly. Here, in primary auditory cortical slices, we examined thalamic innervation patterns for excitatory and different types of inhibitory neurons across laminae, by optogen... | ['Animals', 'Auditory Cortex', 'Excitatory Postsynaptic Potentials', 'Female', 'Inhibitory Postsynaptic Potentials', 'Male', 'Mice, Transgenic', 'Microscopy, Fluorescence', 'Neural Pathways', 'Neuroanatomical Tract-Tracing Techniques', 'Neurons', 'Optogenetics', 'Parvalbumins', 'Patch-Clamp Techniques', 'Somatostatin',... | 25,979,090 | [['B01.050'], ['A08.186.211.200.885.287.500.814.249', 'A08.186.211.200.885.287.500.863.297'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['G04.580.887.374', 'G07.265.675.887.374', 'G07.265.755.500', 'G07.265.880.750.400', 'G11.561.570.918.374', 'G11.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Global effects of the energetics of coenzyme binding: NADPH controls the protein interaction properties of human cytochrome P450 reductase. | The thermodynamics of coenzyme binding to human cytochrome P450 reductase (CPR) and its isolated FAD-binding domain have been studied by isothermal titration calorimetry. Binding of 2',5'-ADP, NADP(+), and H(4)NADP, an isosteric NADPH analogue, is described in terms of the dissociation binding constant (K(d)), the enth... | ['Adenosine Diphosphate', 'Calorimetry', 'Coenzymes', 'Cytochromes c', 'Humans', 'Kinetics', 'NADP', 'NADPH-Ferrihemoprotein Reductase', 'Oxidation-Reduction', 'Phosphates', 'Protein Binding', 'Protein Conformation', 'Protein Structure, Tertiary', 'Temperature', 'Thermodynamics', 'Titrimetry'] | 16,445,284 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['E05.196.131'], ['D08.211'], ['D08.244.286.100', 'D12.776.422.220.286.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['D03.633.100.759.646.138.749', 'D08.211.625', 'D13.695.667.138.749', 'D13.695.82... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Interprofessional Education in U.S. Dental Hygiene Programs: Program Director Responses Before and After Introduction of CODA Standard 2-15. | A 2014 survey found that dental hygiene program directors perceived interprofessional education (IPE) as a priority for themselves and the dental hygiene profession in the U.S. The aim of this study was to explore whether IPE collaborations in dental hygiene programs and program directors' attitudes changed from 2014 t... | ['Curriculum', 'Dental Hygienists', 'Humans', 'Interprofessional Relations', 'Schools, Dental', 'Surveys and Questionnaires', 'United States'] | 30,600,245 | [['I02.158'], ['M01.526.485.067.105.376', 'N02.360.067.105.376'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205'], ['I02.783.495.481'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['Z01.107.567.875']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Phenotypical and functional characterization of Herpesvirus saimiri-immortalized human major histocompatibility complex class II-deficient T lymphocytes. | CD8+ T lymphocytes from two unrelated cases of MHC class II deficiency were immortalized in vitro using Herpesvirus saimiri. In both cases, a lack of expression of surface MHC class II molecules was ascertained, whereas variable defects were shown for MHC class I, CD74 (invariant chain) and LAG-3 (an MHC class II ligan... | ['Cell Transformation, Viral', 'Female', 'Herpesvirus 2, Saimiriine', 'Histocompatibility Antigens Class II', 'Humans', 'Immunophenotyping', 'Infant', 'T-Lymphocytes'] | 9,550,325 | [['C04.697.098.500.160', 'C23.550.727.098.500.160', 'G06.920.143'], ['B04.280.210.400.700.400', 'B04.280.382.400.700.400', 'B04.613.204.500.700.400'], ['D12.776.395.550.509', 'D12.776.543.550.440', 'D23.050.301.500.400', 'D23.050.705.552.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.447', 'E... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A prospective study of end-to-side vs. side-to-side arteriovenous fistulas for haemodialysis. | In an attempt to determine the optimum configuration of arteriovenous (A-V) fistulas for haemodialysis, 71 patients were prospectively randomized to undergo either a side-to-side or end-of-vein to side-of-artery A-V fistula. Nine months after operation, the patency rates on dialysis were almost identical in the two gro... | ['Arteriovenous Shunt, Surgical', 'Blood Flow Velocity', 'Blood Pressure', 'Female', 'Humans', 'Intraoperative Period', 'Male', 'Postoperative Complications', 'Postoperative Period', 'Prospective Studies', 'Random Allocation', 'Regional Blood Flow', 'Renal Dialysis', 'Thrombosis', 'Wrist'] | 6,743,990 | [['E04.035.087', 'E04.100.814.868.249'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E01.370.600.875.249', 'G09.330.380.076'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374', 'N02.421.585.753.374'], ['C23.550.767'], ['E04.614.750', 'N02.421.585.753.750'], ['E05.318.372.500.750.625', 'N05.715.360.330.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
On-treatment monitoring of liver fibrosis with serum hepatitis B core-related antigen in chronic hepatitis B. | BACKGROUND: Non-invasive evaluation for liver fibrosis is clinically important, especially in patients with undetectable hepatitis B virus (HBV) DNA treated with nucleoside analogs.AIM: To clarify the monitoring power of hepatitis B core-related antigen (HBcrAg) for hepatic histologic changes in patients with chronic h... | ['Adult', 'Antiviral Agents', 'Biomarkers', 'DNA, Viral', 'Disease Progression', 'Female', 'Guanine', 'Hepatitis B Core Antigens', 'Hepatitis B virus', 'Hepatitis B, Chronic', 'Humans', 'Liver', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Prospective Studies', 'Treatment Outcome'] | 31,528,100 | [['M01.060.116'], ['D27.505.954.122.388'], ['D23.101'], ['D13.444.308.568'], ['C23.550.291.656'], ['D03.633.100.759.758.399.454'], ['D23.050.327.495.500.450'], ['B04.280.375.650.425', 'B04.450.390.650.425'], ['C01.221.250.500.100', 'C01.925.256.430.400.100', 'C01.925.440.435.100', 'C06.552.380.350.100', 'C06.552.380.70... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Detection of polymorphic epithelial mucins in the serum of systemic breast cancer patients using the monoclonal antibody, NCRC-11. | Serum from patients with systemic breast cancer was found to contain elevated levels of polymorphic epithelial mucin (PEM) as detected using an immunoradiometric assay employing the monoclonal antibody NCRC-11. PEM was partially purified from pooled sera from these patients and the complex, polymorphic, high-molecular-... | ['Antibodies, Monoclonal', 'Antigens, Neoplasm', 'Breast Neoplasms', 'Female', 'Humans', 'Immunoradiometric Assay', 'Mucins', 'Time Factors'] | 2,376,045 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.285'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.639.405', 'E05.601.470.639.405'], ['D12.776.395.560.631'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prenatal color and pulsed Doppler sonographic documentation of intrathoracic umbilical vein and ductus venosus, confirming extensive hepatic herniation in left congenital diaphragmatic hernia. | Prenatal sonographic diagnosis of an unusual case of a large left congenital diaphragmatic hernia is presented. The fetal stomach was located within the right thorax, posterior to the dextropositioned heart. Color and pulsed Doppler ultrasonography documented intrathoracic umbilical vein and ductus venosus vessels and ... | ['Adult', 'Dextrocardia', 'Female', 'Hernia, Diaphragmatic', 'Hernias, Diaphragmatic, Congenital', 'Humans', 'Liver', 'Pregnancy', 'Ultrasonography, Doppler, Color', 'Ultrasonography, Doppler, Pulsed', 'Ultrasonography, Prenatal', 'Umbilical Veins'] | 8,688,107 | [['M01.060.116'], ['C14.240.400.280', 'C14.280.400.280', 'C16.131.240.400.280', 'C16.131.810.250'], ['C23.300.707.960.500'], ['C16.131.433', 'C23.300.707.960.500.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['G08.686.784.769'], ['E01.370.350.850.850.850.850'], ['E01.370.350.850.850.860'], ['E01.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Simultaneous combined supra-infrasellar approach for giant/large multilobulated pituitary adenomas. | BACKGROUND: Surgical treatment of few complex pituitary adenomas, mostly large/giant and multilobulated, still remains troublesome. We present our case series using a simultaneous combined supra-infrasellar approach for these tumors.METHODS: We retrospectively reviewed our 29 consecutive patients who have undergone pro... | ['Adolescent', 'Adult', 'Aged', 'Cavernous Sinus', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neurosurgical Procedures', 'Ophthalmoplegia', 'Pituitary Function Tests', 'Pituitary Neoplasms', 'Postoperative Complications', 'Retrospective Studies', 'Sella Turcica', 'Treatment Outcome', 'Vision Disorders', 'Young Adult'] | 22,120,331 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A07.015.908.224.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.525'], ['C10.292.562.750', 'C10.597.622.447', 'C11.590.472', 'C23.888.592.636.447'], ['E01.370.374.605'], ['C04.588.322.609', 'C04.588.614.250.195.885.500.600', 'C... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Accumulation of terpenoid phytoalexins in maize roots is associated with drought tolerance. | Maize (Zea mays) production, which is of global agro-economic importance, is largely limited by herbivore pests, pathogens and environmental conditions, such as drought. Zealexins and kauralexins belong to two recently identified families of acidic terpenoid phytoalexins in maize that mediate defence against both patho... | ['Abscisic Acid', 'Adaptation, Physiological', 'Biosynthetic Pathways', 'Droughts', 'Herbivory', 'Plant Diseases', 'Plant Growth Regulators', 'Plant Proteins', 'Plant Roots', 'Signal Transduction', 'Stress, Physiological', 'Terpenes', 'Zea mays'] | 25,392,907 | [['D02.241.223.268.034', 'D02.455.326.271.665.202.061', 'D02.455.426.392.368.367.379.249.024', 'D02.455.849.131.061', 'D02.455.849.765.521.500'], ['G07.025', 'G16.012.500'], ['G02.111.098', 'G03.493.100'], ['G16.500.175.781', 'G16.500.750.775.154', 'N06.230.100.230.150'], ['F01.145.113.547.600', 'F01.145.407.758', 'G07... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Circuit librarian serves five hospitals in shared program. | There is increasing emphasis on continuing education of hospital personnel, who need and want access to information in order to be aware of advances in health care. Small hospitals cannot afford to duplicate extensive collections. Personnel of hospitals that are remote from urban centers often do not have opportunities... | ['Education, Continuing', 'Hospital Shared Services', 'Library Services', 'Ohio', 'Personnel, Hospital'] | 939,511 | [['I02.358.212'], ['N02.278.216.500.990', 'N04.452.442.452.565', 'N04.452.540.308'], ['L01.453.639', 'L01.583.464'], ['Z01.107.567.875.075.512', 'Z01.107.567.875.350.540', 'Z01.107.567.875.510.540'], ['M01.526.485.740', 'N02.360.740']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Information Science [L]', 'Geographicals [Z]', 'Named Groups [M]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Change in intraocular pressure during maturation in Labrador Retriever dogs. | OBJECTIVE: To measure intraocular pressure (IOP) in a group of dogs as puppies and young adults to determine if there is any change during maturation. Animals studied Thirty-two healthy Labrador Retriever dogs.PROCEDURES: Intraocular pressure was measured using a Tonopen XL initially at approximately 6 weeks of age (T1... | ['Animals', 'Animals, Newborn', 'Dogs', 'Female', 'Intraocular Pressure', 'Male', 'Pedigree', 'Reference Values'] | 14,982,587 | [['B01.050'], ['B01.050.050.282'], ['B01.050.150.900.649.313.750.250.216.200'], ['G14.440'], ['E05.393.673'], ['E05.978.810']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Credit-card sized field and benchtop NMR relaxometers using field programmable gate arrays. | The tools for developing systems for NMR improve each year. Some firmware based designs based on Field Programmable Gate Arrays (FPGAs) have been developed to implement both the core and peripheral apparatus for NMR Relaxometers and NMR Cryoporometers. Hand held in size they are particularly suitable for desktop, mobil... | ['Equipment Design', 'Magnetic Resonance Spectroscopy', 'Signal Processing, Computer-Assisted'] | 30,344,057 | [['E05.320'], ['E05.196.867.519'], ['L01.224.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Isolation and characterization of the plasma membranes of cultured lymphoblasts from patients with cystic fibrosis and normal individuals. | Plasma membranes were isolated from two cystic fibrosis lymphoblastoid cell lines and two age and sex-matched normal cell lines after controlled cell disruption. The preparations were enriched approx. 20-fold in plasma membrane markers and were essentially free of markers for other organelles except the Golgi-localized... | ['Carbohydrates', 'Cell Fractionation', 'Cell Line', 'Cell Membrane', 'Cystic Fibrosis', 'Humans', 'Lymphocytes', 'Membrane Fluidity', 'Membrane Lipids', 'Membrane Proteins'] | 7,417,420 | [['D09'], ['E05.242.251'], ['A11.251.210'], ['A11.284.149'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567', 'A15.145.229.637.555.567', 'A15.382.490.555.567'], ['G01.154.500', 'G02.111.550', 'G04.570'], ['D10.570'], ['D12.776.543']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An unusual case of benign hibernoma in the paediatric age group. | An unusual case of congenital benign hibernoma, in the submandibular region, in a 2.5 years old girl, is reported, who presented with a progressively increasing neck swelling. A CAT scan of neck revealed a superficial and deep low density mass. Surgical excision revealed a benign hibernoma. A 3-year follow-up shows no ... | ['Child, Preschool', 'Female', 'Follow-Up Studies', 'Head and Neck Neoplasms', 'Humans', 'Lipoma', 'Neck', 'Soft Tissue Neoplasms', 'Time Factors', 'Tomography, X-Ray Computed'] | 16,542,612 | [['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.550.400'], ['A01.598'], ['C04.588.839'], ['G01.910.857'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Dorsal medullary compression due to a primary vertebral chondrosarcoma]. | INTRODUCTION: Chondrosarcomas are the second commonest type of bony tumors, although they are not commonly found to be vertebral. They may originate in healthy bone or develop in a cartilaginous lesion with sarcomatous degeneration.CLINICAL CASE: A 62 year old woman complained of pain in the back and weakness of her le... | ['Bone Neoplasms', 'Chondrosarcoma', 'Female', 'Humans', 'Middle Aged', 'Spinal Cord Compression', 'Thoracic Vertebrae', 'Tomography, X-Ray Computed'] | 10,789,139 | [['C04.588.149', 'C05.116.231'], ['C04.557.450.565.280', 'C04.557.450.795.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.228.854.761', 'C26.819.678'], ['A02.835.232.834.892'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810',... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An exploration of the perceptions of male partners involved in the birthing experience at a regional Australian hospital. | INTRODUCTION: The benefits to women of having their male partners present during labor and birth have been well documented, but the effects on men of sharing the birth experience have been less well explored. Several studies have suggested that male partners' positive experiences at this time may benefit partner and fa... | ['Adult', 'Attitude to Health', 'Delivery, Obstetric', 'Female', 'Hospitals', 'Humans', 'Labor, Obstetric', 'Male', 'Men', 'Perception', 'Pregnancy', 'Prenatal Care', 'Sexual Partners', 'Social Support', 'Spouses', 'Surveys and Questionnaires', 'Young Adult'] | 23,279,049 | [['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['E04.520.252'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769.326'], ['M01.390'], ['F02.463.593'], ['G08.686.784.769'], ['E02.760.786', 'N02.421.143.620.704', 'N02.421.585.786'], ['M01.778'], ['I01.880.853.500.600'], ['F01.829.263.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Behavioral observations and operant procedures using microwaves as a heat source for young chicks. | Four trials, using operant conditioning procedures, were conducted to study the response of chicks, housed at 16 C, to microwave or infrared heat. Microwave power density was 26 mW/cm2 in Trial 1, 13 mW/cm2 in Trial 2, and 10 mW/cm2 in Trials 3 and 4. Chicks voluntarily demanded between 28 and 63% as much heat (min hea... | ['Animals', 'Behavior, Animal', 'Conditioning, Operant', 'Hot Temperature', 'Infrared Rays', 'Microwaves'] | 3,588,476 | [['B01.050'], ['F01.145.113'], ['F02.463.425.179.509'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G01.358.500.505.650.552', 'G01.590.540.552', 'G01.750.250.650.552', 'G01.750.770.578.552', 'G16.500.275.063.725.525.400', 'G1... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Characterization of Taenia solium cysticerci microsomal glutathione S-transferase activity. | Glutathione S-transferase activity has been shown to be associated with the microsomal fraction of Taenia solium. Electron microscopy and subcellular enzyme markers indicate the purity of the microsomal fraction that contains the glutathione S-transferase activity. T. solium microsomes were solubilized under conditions... | ['Aldehydes', 'Alkadienes', 'Animals', 'Dinitrochlorobenzene', 'Enzyme Inhibitors', 'Enzyme Stability', 'Glutathione Peroxidase', 'Glutathione Transferase', 'Hydrogen-Ion Concentration', 'Kinetics', 'Microsomes', 'Nitrobenzenes', 'Taenia solium'] | 17,704,948 | [['D02.047'], ['D02.455.326.271.665.146'], ['B01.050'], ['D02.455.426.559.389.261.250', 'D02.455.426.559.389.565.250', 'D02.455.526.439.202.200', 'D02.640.529.240.250', 'D23.050.550.480.350'], ['D27.505.519.389'], ['E05.916.360', 'G02.111.700.500'], ['D08.811.682.732.500'], ['D08.811.913.225.500'], ['G02.300'], ['G01.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Coronary involvement in Mediterranean spotted fever. | Mediterranean spotted fever (MSF) is a tick-borne acute febrile disease caused by Rickettsia conorii and characterized by fever, a maculo-papular rash and a black eschar at the site of the tick bite. We describe the case of a 3-year-old boy with MSF who developed a transient right coronary artery ectasia. The patient w... | ['Boutonneuse Fever', 'Child, Preschool', 'Coronary Artery Disease', 'Dilatation, Pathologic', 'Echocardiography', 'Humans', 'Italy', 'Male', 'Rickettsia conorii'] | 22,143,818 | [['C01.150.252.400.789.725.400.250', 'C01.920.930.887.250'], ['M01.060.406.448'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['C23.300.325'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['B03.660.050... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
National campaign effects on secondary pupils' bullying and violence. | BACKGROUND: Research on pupils' bullying (1991) and violence (1993) motivated the Dutch Ministry of Education, Culture and Science to initiate a national campaign on school safety. The government campaign was undertaken from 1995 to 2000.AIM: To test for differences in secondary pupils' bullying and violence before and... | ['Adolescent', 'Aggression', 'Child', 'Child Behavior', 'Dominance-Subordination', 'Female', 'Humans', 'Male', 'Netherlands', 'Program Evaluation', 'Students', 'Surveys and Questionnaires', 'Violence'] | 16,238,878 | [['M01.060.057'], ['F01.145.126.125', 'F01.145.813.045'], ['M01.060.406'], ['F01.145.179'], ['F01.145.813.650.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.651'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['M01.848'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['I01.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Mass balance of base equivalents during hemodialysis: importance of organic acid anions. | Acid-base changes during hemodialysis cannot be calculated solely from the balance of acetate and bicarbonate. Organic acid losses strongly influence acid-base balance during hemodialysis. Changes in organic acid concentrations might alter acid-base balance in hemodialysis patients. | ['Acetates', 'Acetoacetates', 'Acid-Base Equilibrium', 'Acidosis', 'Bicarbonates', 'Blood', 'Carbon Dioxide', 'Carboxylic Acids', 'Citrates', 'Homeostasis', 'Humans', 'Hydrogen-Ion Concentration', 'Hydroxybutyrates', 'Kidney Failure, Chronic', 'Lactates', 'Pyruvates', 'Renal Dialysis'] | 40,220 | [['D02.241.081.018', 'D10.251.400.045'], ['D02.241.755.080', 'D02.522.585.175'], ['G02.111.007', 'G02.300.176', 'G03.030', 'G07.410.110', 'G09.188.050'], ['C18.452.076.176'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['A12.207.152', 'A15.145'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D02.241'], [... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Trace elements in size-segregated urban aerosol in relation to the anthropogenic emission sources and the resuspension. | Size segregated particulate samples of atmospheric aerosols in urban site of continental part of Balkans were collected during 6 months in 2008. Six stages impactor in the size ranges: Dp ? 0.49 ìm, 0.49 < Dp ? 0.95 ìm, 0.95 < Dp ? 1.5 ìm, 1.5 < Dp ? 3.0 ìm, 3.0 < Dp ? 7.2 ìm, and 7.2 < Dp ? 10.0 ìm was applied for sam... | ['Aerosols', 'Air Pollutants', 'Atmosphere', 'Cities', 'Environmental Monitoring', 'Metals', 'Particle Size', 'Principal Component Analysis', 'Serbia'] | 24,859,696 | [['D20.280.055', 'D26.255.165.055'], ['D27.888.284.101'], ['G16.500.275.063', 'N06.230.300.100'], ['G16.500.275.069', 'N06.230.069', 'Z01.433'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D01.552'], ['G02.712'], ['E05.318.740.562'], ['Z01.542.248.786']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Plate fixation versus intramedullary fixation for midshaft clavicle fractures: Meta-analysis of complications and functional outcomes. | OBJECTIVE: This analysis critically compares publications discussing complications and functional outcomes of plate fixation (PF) versus intramedullary fixation (IF) for midshaft clavicle fractures.METHODS: Relevant studies published between January 1990 and October 2014, without language restrictions, were identified ... | ['Adolescent', 'Adult', 'Bone Plates', 'Brachial Plexus', 'Clavicle', 'Female', 'Fracture Fixation, Intramedullary', 'Fractures, Bone', 'Fractures, Malunited', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Range of Motion, Articular', 'Recovery of Function', 'Reoperation', 'Treatment Outcome'] | 26,880,791 | [['M01.060.057'], ['M01.060.116'], ['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['A08.800.800.720.050'], ['A02.835.232.087.227'], ['E04.555.300.300.300'], ['C26.404'], ['C26.404.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E01.370.600.700'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cardiac injury after subarachnoid hemorrhage is independent of the type of aneurysm therapy. | OBJECTIVE: Subarachnoid hemorrhage (SAH) is associated with cardiac injury and dysfunction. Whether aneurysm clipping versus coiling has a differential effect on the risk of troponin release and left ventricular (LV) dysfunction after SAH is unknown. It is hypothesized that aneurysm treatment does not affect the risk o... | ['Cohort Studies', 'Female', 'Humans', 'Intracranial Aneurysm', 'Male', 'Middle Aged', 'Prospective Studies', 'Subarachnoid Hemorrhage', 'Treatment Outcome', 'Troponin', 'Vascular Surgical Procedures', 'Ventricular Dysfunction, Left'] | 15,574,206 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.510.600', 'C14.907.055.635', 'C14.907.253.560.300'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C10.22... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Coordination between posture and phonation in vocal effort behavior. | BACKGROUND: Postural correlates of vocal effort are rarely described in the literature, while they are extensively dealt with in speech therapy.OBJECTIVES: This study aims at determining whether body movement is a side effect of vocal effort or an integral part of communication effort behavior. The answer to this quest... | ['Abdomen', 'Adult', 'Biomechanical Phenomena', 'Communication', 'Electrodiagnosis', 'Female', 'Glottis', 'Head Movements', 'Humans', 'Motor Activity', 'Phonation', 'Posture', 'Sound Spectrography', 'Speech Acoustics', 'Task Performance and Analysis', 'Thigh', 'Time Factors', 'Voice', 'Voice Quality', 'Young Adult'] | 20,460,932 | [['A01.923.047'], ['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['F01.145.209', 'L01.143'], ['E01.370.405'], ['A04.329.364'], ['G11.427.410.478'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.632', 'G11.427.410.698'], ['G09.772.585'], ['G11.427.695'], ['E05.855'], ['G11.561.812.650', 'G11.561.820'], ['... | ['Anatomy [A]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Echocardiographic Doppler assessments of left ventricular filling and ejection during upright exercise in endurance athletes. | Doppler echocardiography was used to describe left ventricular filling and ejection during upright bicycle exercise in 24 healthy male endurance athletes. The transmitral pressure gradient was estimated and isovolumetric relaxation, filling and ejection time and transmitral and aortic flow velocities were measured at r... | ['Adult', 'Echocardiography, Doppler', 'Exercise Test', 'Heart Ventricles', 'Humans', 'Image Interpretation, Computer-Assisted', 'Male', 'Physical Endurance', 'Physical Exertion', 'Posture', 'Stroke Volume', 'Ventricular Function'] | 17,204,036 | [['M01.060.116'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 |
Determination of lamb wave dispersion data in lossy anisotropic plates using time domain finite element analysis. Part II: application to 2-2 and 1-3 piezoelectric composite transducer arrays. | The use of finite element modeling, combined with optical generation and detection of Lamb waves in plate structures, was extended to encompass periodic ceramic-polymer materials typical of those encountered in 1-3 and 2-2 piezoelectric composite array transducers. The resultant dispersion data was employed to predict ... | ['Anisotropy', 'Computer Simulation', 'Elasticity', 'Electrochemistry', 'Energy Transfer', 'Finite Element Analysis', 'Models, Chemical', 'Polymers', 'Stress, Mechanical', 'Transducers', 'Ultrasonography', 'Vibration'] | 16,529,120 | [['G01.590.040', 'G02.050'], ['L01.224.160'], ['G01.374.590'], ['H01.181.529.307'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['E05.355'], ['E05.599.495'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['G01.374.835'], ['E07.305.812'], ['E01.370.350.850'], ['G01.374.930']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Very severe anemia and one year mortality outcome after hospitalization in Tanzanian children: A prospective cohort study. | BACKGROUND: Africa has the highest rates of child mortality. Little is known about outcomes after hospitalization for children with very severe anemia.OBJECTIVE: To determine one year mortality and predictors of mortality in Tanzanian children hospitalized with very severe anemia.METHODS: We conducted a prospective coh... | ['Anemia', 'Cause of Death', 'Child', 'Child, Preschool', 'Female', 'Hospitalization', 'Humans', 'Male', 'Mortality', 'Prevalence', 'Prospective Studies', 'Regression Analysis', 'Risk Factors', 'Tanzania'] | 31,220,109 | [['C15.378.071'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['M01.060.406'], ['M01.060.406.448'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.550', 'N01.224.935.698', 'N06.850.505.400.975.5... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Role of oral anticoagulation and inoue balloon mitral valvulotomy in presence of left atrial thrombus: a prospective serial transesophageal echocardiographic study. | BACKGROUND AND AIMS OF THE STUDY: Left atrial (LA) and/or left atrial appendage (LAA) thrombi are often found in patients with rheumatic mitral stenosis (MS). The fate of these thrombi on optimal oral anticoagulation, and the feasibility of balloon mitral valvulotomy (BMV) is not well established. The study aims were t... | ['Acenocoumarol', 'Administration, Oral', 'Adult', 'Anticoagulants', 'Catheterization', 'Dose-Response Relationship, Drug', 'Echocardiography, Transesophageal', 'Female', 'Follow-Up Studies', 'Heart Atria', 'Heart Diseases', 'Humans', 'Male', 'Middle Aged', 'Mitral Valve Stenosis', 'Probability', 'Prospective Studies',... | 12,150,310 | [['D03.383.663.283.446.520.079', 'D03.633.100.150.446.520.079'], ['E02.319.267.100'], ['M01.060.116'], ['D27.505.954.502.119'], ['E02.148', 'E05.157'], ['G07.690.773.875', 'G07.690.936.500'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.380.220.235'], ['E05.318.372.500.750.249', 'N05.715.360.330.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A repeatedly refuelable mediated biofuel cell based on a hierarchical porous carbon electrode. | Biofuel cells that generate electricity from renewable fuels, such as carbohydrates, must be reusable through repeated refuelling, should these devices be used in consumer electronics. We demonstrate the stable generation of electricity from a glucose-powered mediated biofuel cell through multiple refuelling cycles. Th... | ['Bioelectric Energy Sources', 'Carbon', 'Electrochemistry', 'Electrodes', 'NAD', 'Porosity'] | 24,820,210 | [['E07.305.124.150'], ['D01.268.150'], ['H01.181.529.307'], ['E07.305.250'], ['D03.633.100.759.646.138.694', 'D08.211.589', 'D13.695.667.138.694', 'D13.695.827.068.694'], ['G01.374.710']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Promoter methylation regulates SAMHD1 gene expression in human CD4+ T cells. | The retrovirus restriction factor SAMHD1 is the first identified mammalian dNTP triphosphohydrolase that is highly expressed in human myeloid lineage cells and CD4(+) T lymphocytes. Although SAMHD1 expression is variable in human cell lines and tissue types, mechanisms underlying SAMHD1 gene regulation have not been de... | ['Base Sequence', 'CD4-Positive T-Lymphocytes', 'Cell Proliferation', 'CpG Islands', 'DNA Methylation', 'Epigenesis, Genetic', 'Gene Expression Regulation', 'HEK293 Cells', 'Humans', 'Jurkat Cells', 'Molecular Sequence Data', 'Monocytes', 'Monomeric GTP-Binding Proteins', 'Promoter Regions, Genetic', 'SAM Domain and HD... | 23,426,363 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['G04.161.750', 'G07.345.249.410.750'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['G02.111.035.538.161', 'G02.111.218', 'G03.05... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A simple but effective ferrocene derivative as a redox, colorimetric, and fluorescent receptor for highly selective recognition of Zn2+ ions. | A new probe, based on a 1,1'-disubstituted ferrocene, senses Zn2+ selectively among heavy and transition-metal (HTM) ions through three different channels: anodic redox shift of the Fe(II)/Fe(III) redox couple, the orange to deep purple color change that is visible to the naked-eye, and a remarkable enhancement of the ... | ['Colorimetry', 'Ferrous Compounds', 'Fluorescent Dyes', 'Metallocenes', 'Models, Chemical', 'Molecular Structure', 'Oxidation-Reduction', 'Sensitivity and Specificity', 'Zinc'] | 17,503,839 | [['E05.196.922.250'], ['D01.490.200'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D02.691.657'], ['E05.599.495'], ['G02.111.570', 'G02.466'], ['G02.700', 'G03.295.531'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.850.520.830.872'], ... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Highly diastereoselective preparation of anti-1,2-diols by catalytic addition of alkynylsilanes to alpha-silyloxyaldehydes. | The catalytic, diastereoselective coupling of alpha-silyloxy aldehydes and alkynylsilanes catalyzed by a nickel(0) N-heterocyclic carbene complex provides an effective entry to anti-1,2-diols. The scope of couplings and extent of diastereoselection are excellent across a range of substrates. | ['Aldehydes', 'Catalysis', 'Magnetic Resonance Spectroscopy', 'Silanes', 'Stereoisomerism'] | 16,986,920 | [['D02.047'], ['G02.130'], ['E05.196.867.519'], ['D01.837.700'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evanescent wave long-period fiber bragg grating as an immobilized antibody biosensor. | An immunosensor using a long-period grating (LPG) was used for sensitive detection of antibody-antigen reactions. Goat anti-human IgG (antibody) was immobilized on the surface of the LPG, and detection of specific antibody-antigen binding was investigated. This sensor operates using total internal reflection where an e... | ['Animals', 'Antibodies', 'Antigen-Antibody Reactions', 'Biosensing Techniques', 'Goats', 'Humans', 'Indicators and Reagents', 'Signal Processing, Computer-Assisted'] | 10,905,324 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['G12.122'], ['E05.601.043'], ['B01.050.150.900.649.313.500.380.513'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.410'], ['L01.224.800']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Hereditary angioedema with gastrointestinal involvement: endoscopic appearance. | We present the first reported case of hereditary angioedema (HAE) with gastric involvement to be successfully evaluated by endoscopy both during and after an attack. A 31-year-old man who had a family history of angioedema was admitted to our hospital with complaints of abdominal pain and swelling of extremities. Compu... | ['Adult', 'Angioedema', 'Complement C1 Inactivator Proteins', 'Complement C4', 'Endoscopy, Gastrointestinal', 'Gastric Mucosa', 'Humans', 'Intestinal Mucosa', 'Male'] | 10,376,461 | [['M01.060.116'], ['C14.907.079', 'C17.800.862.945.066', 'C20.543.480.904.066'], ['D12.644.861.140', 'D12.776.124.486.274.920.250', 'D12.776.872.140'], ['D12.776.124.486.274.350'], ['E01.370.372.250.250', 'E01.370.388.250.250.250', 'E04.210.240.250', 'E04.502.250.250.250'], ['A03.556.875.875.440', 'A10.615.550.291'], [... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dominant replication of either virus in dual infection with hepatitis viruses B and C. | To characterize the state of dual infection with hepatitis B virus (HBV) and hepatitis C virus (HCV), HBV-DNA and HCV-RNA levels were determined by spot hybridization or polymerase chain reaction in the sera of patients who were positive for both hepatitis B surface antigen and HCV antibody. Among 27 patients who showe... | ['Adolescent', 'Adult', 'Aged', 'Base Sequence', 'DNA Primers', 'DNA, Viral', 'Female', 'Genome, Viral', 'Hepacivirus', 'Hepatitis Antibodies', 'Hepatitis B', 'Hepatitis B Surface Antigens', 'Hepatitis B virus', 'Hepatitis C', 'Hepatitis C Antibodies', 'Hepatitis, Chronic', 'Humans', 'Male', 'Middle Aged', 'Molecular S... | 7,539,830 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.568'], ['G05.360.340.358.840'], ['B04.450.380', 'B04.820.578.344.475'], ['D12.776.124.486.485.114.254.450', 'D12.776.124.790.651.11... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Curcumin blocks fibrosis in anti-Thy 1 glomerulonephritis through up-regulation of heme oxygenase 1. | BACKGROUND: Induction of heme oxygenase 1 (HO-1) has been shown to be beneficial in a variety of pathologic settings. Curcumin, a polyphenolic compound, has antifibrotic effects in lung models of fibrosis, and is known to induce HO-1 in renal tubular cells. In this study, we determined whether curcumin has antifibrotic... | ['Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Curcumin', 'Drug Interactions', 'Enzyme Inhibitors', 'Fibrosis', 'Glomerulonephritis', 'Heme Oxygenase-1', 'Isoantibodies', 'Kidney Glomerulus', 'Male', 'Proteinuria', 'Rats', 'Rats, Sprague-Dawley', 'Up-Regulation'] | 16,221,204 | [['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D02.455.326.146.485.222.222', 'D02.455.426.559.389.657.166.200', 'D02.455.426.559.694.222'], ['G07.690.773.968'], ['D27.505.519.389'], ['C23.550.355'], ['C12.777.419.570.363', 'C13.351.968.419.570.363'], ['D08.811.682.690... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Risk of lower limb amputation in a national prevalent cohort of patients with diabetes. | AIMS/HYPOTHESIS: Lower limb amputation is a serious complication of diabetes mellitus. Understanding how amputation risk differs by population subgroups is crucial in terms of directing preventive strategies. In this study, we describe those factors that impact amputation risk in the entire prevalent diabetic populatio... | ['Adult', 'Aged', 'Amputation', 'Cohort Studies', 'Comorbidity', 'Diabetes Mellitus', 'Female', 'Hospitalization', 'Humans', 'Lower Extremity', 'Male', 'Middle Aged', 'Proportional Hazards Models', 'Risk Factors', 'Treatment Outcome'] | 29,101,423 | [['M01.060.116'], ['M01.060.116.100'], ['E04.555.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.225', 'N06.850.490.687'], ['C18.452.394.750', 'C19.246'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610'], ['M01.060.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis. | The mechanistic/mammalian target of rapamycin complex 1 (mTORC1) regulates cellular function in various cell types. Although the role of mTORC1 in skeletogenesis has been investigated previously, here we show a critical role of mTORC1/4E-BPs/SOX9 axis in regulating skeletogenesis through its expression in undifferentia... | ['Animals', 'Cell Differentiation', 'Gene Expression', 'Mechanistic Target of Rapamycin Complex 1', 'Mice', 'Mice, Transgenic', 'Osteogenesis', 'Phenotype', 'Protein Biosynthesis', 'SOX9 Transcription Factor', 'Skeleton'] | 30,008,325 | [['B01.050'], ['G04.152'], ['G05.297'], ['D05.500.337', 'D08.811.913.696.620.682.700.931.500', 'D12.776.476.925.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['G07.345.500.325.377.625.050.500.729', 'G11.427.578.050.500.729'], ['G05.695'], ['G... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Heterogeneity of immunoregulatory T-cell subsets in systemic lupus erythematosus. Correlation with clinical features. | Immunoregulatory T-cell subsets as defined by differentiation antigens were studied in 32 patients with systemic lupus erythematosus (SLE) and 16 healthy persons using the monoclonal antibodies OKT 3 or anti-Leu 4 (T cells), anti-Leu 2a (suppressor/cytotoxic cells) and anti-Leu 3a (helper/inducer cells). Compared with ... | ['Adult', 'Antibodies, Monoclonal', 'Antibody Specificity', 'Female', 'Humans', 'Leukocyte Count', 'Lupus Erythematosus, Systemic', 'Male', 'Middle Aged', 'T-Lymphocytes', 'T-Lymphocytes, Regulatory'] | 6,211,094 | [['M01.060.116'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E05.200.625.107.595', 'E05.242.195.107.595', 'G04.140.107.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[A case of bronchial stump recurrence of lung cancer successfully treated with chemoradiotherapy using cisplatin plus vinorelbine]. | A 61-year-old man, who had undergone right upper lobectomy for lung cancer about nineteen months earlier, was examined at our hospital for hemoptysis. A bronchial stump recurrence was observed by chest CT and bronchoscopy. The patient underwent chemoradiotherapy using cisplatin (CDDP) and vinorelbine (VNB). Irradiation... | ['Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma, Non-Small-Cell Lung', 'Cisplatin', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Pneumonectomy', 'Radiotherapy Dosage', 'Vinblastine'] | 11,016,003 | [['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Modulation of cellular anti-tumour responses by tumour-specific T suppressor lymphocytes. | Tumour-specific Ts cells, induced by a protocol which simulates early stages of tumourigenesis in BALB/c mice by the syngeneic plasmacytoma ADJ-PC-5, suppress the generation of specific cytotoxic T lymphocytes (CTL) in a primary in vitro mixed lymphocyte tumour culture (MLTC) of BALB/c spleen cells against ADJ-PC-5. Th... | ['Animals', 'Female', 'Interleukin-2', 'Killer Cells, Natural', 'Lymphocyte Activation', 'Mice', 'Mice, Inbred BALB C', 'Neoplasms, Experimental', 'Plasmacytoma', 'T-Lymphocytes, Cytotoxic', 'T-Lymphocytes, Regulatory', 'Tumor Cells, Cultured'] | 2,975,538 | [['B01.050'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.776.467.374.480.372', 'D23.529.374.465.155', 'D23.529.374.480.372'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ammonia stress on a resilient mesophilic anaerobic inoculum: Methane production, microbial community, and putative metabolic pathways. | Short term inhibition tests, 16S rRNA tag sequencing and Phylogenetic Investigation of Communities by Reconstruction of Unobserved States (PICRUSt), were employed to visualise the effects of increasing total ammoniacal nitrogen (TAN) concentration (3400-10166 ppm TAN) on microbial community structure and metabolic path... | ['Acetic Acid', 'Ammonia', 'Anaerobiosis', 'Metabolic Networks and Pathways', 'Methane', 'Microbiota', 'Oxidation-Reduction', 'Stress, Physiological'] | 30,579,103 | [['D02.241.081.018.165', 'D10.251.400.045.500'], ['D01.362.075', 'D01.625.050'], ['G02.111.062', 'G03.078'], ['G03.493'], ['D02.455.326.146.571'], ['G06.591', 'G16.500.275.157.049.100.500', 'N06.230.124.049.100.500'], ['G02.700', 'G03.295.531'], ['G07.775']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Characteristics associated with fasting appetite hormones (obestatin, ghrelin, and leptin). | Obestatin, derived from the same gene as the hunger hormone ghrelin, may reduce food intake in animals. The role of obestatin in human physiology is unclear. We evaluated cross-sectional associations between participant characteristics and fasting levels of obestatin as well two other hormones associated with energy ba... | ['Adult', 'Blood Pressure', 'Body Mass Index', 'Cross-Sectional Studies', 'Energy Metabolism', 'Fasting', 'Female', 'Ghrelin', 'Humans', 'Leptin', 'Linear Models', 'Male', 'Middle Aged', 'Motor Activity', 'Obesity', 'Overweight'] | 19,057,526 | [['M01.060.116'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G03.295'], ['F01.145.407.400', 'G07.203.650.240.587', 'G07.203.650.353.400'], ['D06... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A MYC-GCN2-eIF2á negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer. | Tumours depend on altered rates of protein synthesis for growth and survival, which suggests that mechanisms controlling mRNA translation may be exploitable for therapy. Here, we show that loss of APC, which occurs almost universally in colorectal tumours, strongly enhances the dependence on the translation initiation ... | ['Adenomatous Polyposis Coli Protein', 'Animals', 'Apoptosis', 'Cell Line, Tumor', 'Cell Movement', 'Cell Proliferation', 'Colon', 'Colorectal Neoplasms', 'Eukaryotic Initiation Factor-2', 'Eukaryotic Initiation Factor-2B', 'Feedback, Physiological', 'Female', 'Gene Expression Regulation, Neoplastic', 'HCT116 Cells', '... | 31,685,988 | [['D05.500.117.249', 'D12.776.220.040', 'D12.776.476.081.249', 'D12.776.624.776.010'], ['B01.050'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['C04.588.274.476.411.307', 'C06.301.37... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Injuries and damage caused by excess stress in body building and power lifting]. | A questionnaire, designed to elict information about training programs, experience and injury profile, was administered to 358 bodybuilders and 60 powerlifters. This was followed by a clinical orthopedic and radiological examination. The upper extremity, particulary the shoulder and elbow joint, showed the highest inju... | ['Adult', 'Athletic Injuries', 'Cumulative Trauma Disorders', 'Elbow Joint', 'Female', 'Humans', 'Knee Injuries', 'Lumbar Vertebrae', 'Male', 'Muscles', 'Risk Factors', 'Shoulder Joint', 'Sports', 'Weight Lifting'] | 2,711,326 | [['M01.060.116'], ['C26.115'], ['C26.844.150'], ['A02.835.583.290'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558.554'], ['A02.835.232.834.519'], ['A02.633', 'A10.690'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725'],... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The effect of noncontingent sensory reinforcement, contingent sensory reinforcement, and response interruption on stereotypical and self-injurious behavior. | Three analyses were conducted to assess the effects of different consequent stimuli on the rate of stereotypical and self-injurious behavior performed by two individuals with severe developmental disabilities and dual sensory impairments. An analogue functional analysis documented an undifferentiated pattern of problem... | ['Adult', 'Behavior Therapy', 'Child', 'Disabled Persons', 'Education of Intellectually Disabled', 'Female', 'Humans', 'Intellectual Disability', 'Male', 'Motivation', 'Reinforcement Schedule', 'Self-Injurious Behavior', 'Stereotyped Behavior'] | 9,085,430 | [['M01.060.116'], ['F04.754.137'], ['M01.060.406'], ['M01.150'], ['F02.784.629.375', 'I02.233.213.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['F01.658', 'F01.752.543.500.750'], ['F02.463.425.770.644'], ['F01.145.126.980'], ['F01.145.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
A technique for serial sampling of cerebrospinal fluid from conscious swine and sheep. | We devised a method for the atraumatic repeated collection of cerebrospinal fluid samples from conscious swine and sheep. Indwelling needles, with injection caps, were secured intracisternally and protected with plastic "crowns" attached to their skulls. The crowns permitted the animals freer movement with minimal risk... | ['Animals', 'Cisterna Magna', 'Evaluation Studies as Topic', 'Male', 'Restraint, Physical', 'Sheep', 'Spinal Puncture', 'Swine'] | 1,666,153 | [['B01.050'], ['A08.186.566.166.686.351'], ['E05.337', 'N05.715.360.335'], ['E02.085.700', 'E05.472.760'], ['B01.050.150.900.649.313.500.380.791'], ['E01.370.225.998.054.790', 'E01.370.376.700', 'E02.800.779', 'E04.074.790', 'E04.665.700', 'E05.200.998.054.790'], ['B01.050.150.900.649.313.500.880']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Human renal clear cell carcinoma: establishment and characterization of a new cell line (G-2101). | A human cell line has been established from a renal adenocarcinoma rib metastasis of a 58-y-old male. This cell line has been maintained in continuous culture for 20 mo. through more than 50 passages. It displays simultaneous expression of the intermediate filaments cytokeratin and vimentin. Flow cytometric analysis of... | ['Adenocarcinoma', 'Cell Line', 'Flow Cytometry', 'Fluorescent Antibody Technique', 'Gene Expression Regulation', 'Humans', 'Keratins', 'Kidney Neoplasms', 'Male', 'Middle Aged', 'Vimentin'] | 2,453,501 | [['C04.557.470.200.025'], ['A11.251.210'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The mouse mafB 5'-upstream fragment directs gene expression in myelomonocytic cells, differentiated macrophages and the ventral spinal cord in transgenic mice. | The b-Zip transcription factor MafB is an essential determinant of neural development and an inducer of monocytic differentiation. The MafB protein is expressed in a variety of tissues including the developing spinal cord, retina, myelomonocytic lineages of hematopoietic cells, and peritoneal macrophages. However, the ... | ["5' Untranslated Regions", 'Animals', 'Avian Proteins', 'Bone Marrow', 'Brain', 'Cell Differentiation', 'Cell Lineage', 'DNA-Binding Proteins', 'Gene Dosage', 'Gene Expression Regulation', 'Genes, Reporter', 'Green Fluorescent Proteins', 'Luminescent Proteins', 'Macrophages', 'MafB Transcription Factor', 'Mice', 'Mice... | 12,966,068 | [['D13.444.735.544.875.885', 'D13.444.735.790.878.885', 'G05.360.340.024.220.880.885', 'G05.360.340.024.340.137.910.885'], ['B01.050'], ['D12.776.095'], ['A15.382.216'], ['A08.186.211'], ['G04.152'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['D12.776.260'], ['G05.380.350'], ['G0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chemical composition and in sacco degradability of four varieties of cassava leaves grown in Southwestern Nigeria in the rumen of sheep. | The nutritive value of leaves of four varieties of cassava (MS 6, TMS 30555, Idileruwa and TMS 30572) were studied through analysis of their chemical components and degradability of their dry matter (DM) and crude protein (CP) in the rumen of sheep. Results of the chemical analyses showed that the leaves of the four va... | ['Animals', 'Digestion', 'Energy Metabolism', 'Male', 'Manihot', 'Minerals', 'Nigeria', 'Plant Leaves', 'Plant Proteins, Dietary', 'Rumen', 'Sheep', 'Species Specificity'] | 20,521,108 | [['B01.050'], ['G07.203.650.250', 'G10.261.190'], ['G03.295'], ['B01.650.940.800.575.912.250.859.797.438.535'], ['D01.578'], ['Z01.058.290.190.565'], ['A18.024.812'], ['D12.776.256.920', 'D12.776.765.836', 'G07.203.300.428.920', 'J02.500.428.920'], ['A13.869.804'], ['B01.050.150.900.649.313.500.380.791'], ['G16.824']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
In vivo detection and imaging of low-density foreign body with microwave-induced thermoacoustic tomography. | Radiography or computed tomography is the most widely available imaging tool for foreign body detection. However, the detectability of low-density substances by x ray is very poor when located in soft tissues. Various dielectric loss factors of foreign bodies contribute great microwave absorption heterogeneity compared... | ['Acoustics', 'Algorithms', 'Animals', 'Calibration', 'Electromagnetic Phenomena', 'Foreign Bodies', 'Glass', 'Humans', 'Image Processing, Computer-Assisted', 'Mice', 'Microwaves', 'Muscles', 'Phantoms, Imaging', 'Surface Properties', 'Swine', 'Temperature', 'Tomography', 'Tomography, X-Ray Computed', 'Wood'] | 19,746,776 | [['H01.671.031'], ['G17.035', 'L01.224.050'], ['B01.050'], ['E05.978.155'], ['G01.358.500'], ['C26.392'], ['J01.637.437'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['B01.050.150.900.649.313.992.635.505.500'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['A02.633',... | ['Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
The prognostic value of QTc interval and QT dispersion following myocardial infarction in patients treated with or without dofetilide. | BACKGROUND: Acute myocardial infarction (MI) is associated with an increased risk of death, with a 1-year mortality close to 10% in patients discharged from hospital alive. During the first year following MI, close to 50% of deaths are assumed to be due to arrhythmic events.HYPOTHESIS: The study was undertaken to deter... | ['Aged', 'Aged, 80 and over', 'Anti-Arrhythmia Agents', 'Denmark', 'Double-Blind Method', 'Electrocardiography', 'Female', 'Follow-Up Studies', 'Humans', 'Long QT Syndrome', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Myocardial Infarction', 'Phenethylamines', 'Prognosis', 'Proportional Hazards Models', 'Risk Fact... | 12,769,249 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.411.097'], ['Z01.542.816.124'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The mitochondrial genome of Ancylostoma tubaeforme from cats in China. | Ancylostoma tubaeforme may infect canids, felids and humans, and pose a potential risk to public health. Polymerase chain reaction (PCR) techniques were used to amplify the complete mitochondrial (mt) genome sequence of A. tubaeforme from cats and to analyse its sequence characteristics after molecular identification b... | ['Ancylostoma', 'Ancylostomiasis', 'Animals', 'Cat Diseases', 'Cats', 'China', 'DNA, Helminth', 'DNA, Mitochondrial', 'Genome, Mitochondrial', 'Phylogeny', 'RNA, Helminth', 'RNA, Ribosomal', 'RNA, Transfer'] | 28,215,215 | [['B01.050.500.500.294.400.968.100.100'], ['C01.610.335.508.700.775.455.154'], ['B01.050'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['Z01.252.474.164'], ['D13.444.308.315'], ['D13.444.308.283.225'], ['G05.360.340.360'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.735.520'], ['D13.444.735.... | ['Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
[Reduction surgery combined with chemotherapy of liver cancer]. | Effects of reduction surgery combined with chemotherapy on DAB induced hepatoma were investigated. DAB hepatoma was transplanted in the liver and subcutaneous tissue of rats. The results were as follows; 1. Reduction surgery prolonged the survival time of rats with DAB induced hepatoma, either in liver (5, 7 days, p le... | ['Animals', 'Antineoplastic Combined Chemotherapy Protocols', 'Combined Modality Therapy', 'Flow Cytometry', 'Humans', 'Liver Neoplasms, Experimental', 'Male', 'Rats', 'Rats, Inbred Strains', 'Tumor Cells, Cultured', 'p-Dimethylaminoazobenzene'] | 3,119,451 | [['B01.050'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['E02.186'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interleukin-2 mediated regulation of mitogen-activated T cell reactivity from different lymphoid sources in patients with squamous cell carcinoma of the oral cavity. | Peripheral blood lymphocytes (PBL) from patients with oral cancer (treated and untreated), oral leukoplakia and healthy donors; lymphocytes from metastatic and non-metastatic lymph nodes (met LNL and non-met LNL); and tumor infiltrating lymphocytes (TIL) were tested for proliferative response to mitogen PHA (phytohemag... | ['Adult', 'Aged', 'Antigens, CD', 'Carcinoma, Squamous Cell', 'Humans', 'Immune Tolerance', 'Interleukin-2', 'Lymphocyte Activation', 'Middle Aged', 'Mouth Neoplasms', 'Receptors, Interleukin-2', 'Recombinant Proteins', 'T-Lymphocytes'] | 2,810,131 | [['M01.060.116'], ['M01.060.116.100'], ['D23.050.301.264.035', 'D23.101.100.110'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.535.425'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.776.467.374.480.372', 'D23.529.374.4... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Estimating respiratory rate from FBG optical sensors by using signal quality measurement. | Non-intrusiveness is one of the advantages of in-bed optical sensor device for monitoring vital signs, including heart rate and respiratory rate. Estimating respiratory rate reliably using such sensors, however, is challenging, due to body movement, signal variation according to different subjects or body positions, et... | ['Humans', 'Movement', 'Polysomnography', 'Respiratory Rate'] | 26,736,396 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410'], ['E01.370.520.625'], ['E01.370.600.875.875', 'G09.772.705.730']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of the expression directed by two HTLV-I promoters in transgenic mice. | We generated several lines of mice transgenic for the lacZ reporter gene under the control of an HTLV-I LTR. Two different LTR were used; one was isolated from a case of Adult T-cell Leukemia (ATL), the other from a case of Tropical Spastic Paraparesis (TSP/HAM). These LTR differed at 18 nucleotide positions. The patte... | ['Animals', 'Astrocytes', 'Brain', 'DNA Methylation', 'DNA, Viral', 'Gene Expression', 'Genes, Reporter', 'Human T-lymphotropic virus 1', 'Humans', 'Immunoenzyme Techniques', 'In Situ Hybridization', 'Mice', 'Mice, Transgenic', 'Paraparesis, Tropical Spastic', 'Point Mutation', 'Promoter Regions, Genetic', 'Transgenes'... | 8,912,210 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['A08.186.211'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['D13.444.308.568'], ['G05.297'], ['G05.360.340.024.340.435'], ['B04.613.807.200.725.400', 'B04.820.650.200.725.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350',... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protein Profile and Morphological Alterations in Penumbra after Focal Photothrombotic Infarction in the Rat Cerebral Cortex. | After ischemic stroke, cell damage propagates from infarct core to surrounding tissues (penumbra). To reveal proteins involved in neurodegeneration and neuroprotection in penumbra, we studied protein expression changes in 2-mm ring around the core of photothrombotic infarct induced in the rat brain cortex by local lase... | ['Animals', 'Brain Infarction', 'Cell Count', 'Cerebral Cortex', 'Light', 'Male', 'Neurons', 'Proteomics', 'Rats, Wistar', 'Signal Transduction', 'Somatosensory Cortex', 'Thrombosis'] | 27,324,898 | [['B01.050'], ['C10.228.140.300.150.477', 'C10.228.140.300.775.200', 'C14.907.253.092.477', 'C14.907.253.855.200', 'C23.550.513.355.250', 'C23.550.717.489.250'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A08.186.211.200.885.287.500'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Morphologies of rabbit retinal ganglion cells with concentric receptive fields. | Rabbit retinal ganglion cells with concentric receptive fields were intracellularly recorded and stained in the isolated superfused eyecup preparation to relate specific physiological response properties to dendritic morphology. Concentric ganglion cells, as traditionally defined, were those that had On or Off centers ... | ['Action Potentials', 'Animals', 'Dendrites', 'Female', 'In Vitro Techniques', 'Male', 'Photic Stimulation', 'Rabbits', 'Retina', 'Retinal Ganglion Cells'] | 2,918,097 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['A08.675.256', 'A11.284.180.225', 'A11.671.240'], ['E05.481'], ['E05.723.729'], ['B01.050.150.900.649.313.968.700'], ['A09.371.729'], ['A08.675.650.850.875', 'A09.371.729.831.875', 'A11.671.650.850.875']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessment and validation of a suite of reverse transcription-quantitative PCR reference genes for analyses of density-dependent behavioural plasticity in the Australian plague locust. | BACKGROUND: The Australian plague locust, Chortoicetes terminifera, is among the most promising species to unravel the suites of genes underling the density-dependent shift from shy and cryptic solitarious behaviour to the highly active and aggregating gregarious behaviour that is characteristic of locusts. This is bec... | ['Animals', 'Crowding', 'Genome, Insect', 'Grasshoppers', 'Insect Proteins', 'Osteonectin', 'Reverse Transcriptase Polymerase Chain Reaction'] | 21,324,174 | [['B01.050'], ['F01.145.875.281'], ['G05.360.340.357'], ['B01.050.500.131.617.678.369'], ['D12.776.093.500'], ['D12.776.157.125.715', 'D12.776.395.600'], ['E05.393.620.500.725']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Seasonal variation characteristics of algae biomass in Chaohu Lake]. | The biomass and distribution of algae community in Chaohu Lake were investigated in 2008. At the same time, the seasonal variations of algae translocation between the sediment and overlying water were also quantitative studied by self-made "algae up/down trap". Chaohu Lake was dominated by Cyanobacteria all the year, a... | ['Biomass', 'China', 'Cyanobacteria', 'Eutrophication', 'Fresh Water', 'Seasons', 'Temperature', 'Water Pollutants'] | 21,072,924 | [['G16.500.275.157.100', 'N06.230.124.100'], ['Z01.252.474.164'], ['B03.280', 'B03.440.475.100'], ['G16.500.285'], ['G16.500.275.280', 'N06.230.232'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Single brain death examination is equivalent to dual brain death examinations. | BACKGROUND: Although the new Practice Parameters for brain death support a single examination, there is paucity of data comparing its impact to dual brain death (DBD) examinations.METHODS: We reviewed all brain deaths in our hospital over a 39-month period and compared the optional single brain death (SBD) exam requiri... | ['Adult', 'Aged', 'Brain', 'Brain Death', 'Cause of Death', 'Cost-Benefit Analysis', 'Female', 'Guideline Adherence', 'Humans', 'Informed Consent', 'Intensive Care Units', 'Male', 'Middle Aged', 'Neurologic Examination', 'Reproducibility of Results', 'Retrospective Studies', 'Tissue and Organ Procurement'] | 21,604,079 | [['M01.060.116'], ['M01.060.116.100'], ['A08.186.211'], ['C10.228.140.151', 'C10.597.606.358.800.200.100', 'C23.550.260.159'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['N03.219.151.125'], ['N04.761.337', 'N05.715.360.395'], ['B01.050.150.900.649.... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Intraductal papillary mucinous neoplasms of the pancreas: differentiation of malignant and benign tumors by endoscopic ultrasound findings of mural nodules. | BACKGROUND AND AIM: Intraductal papillary mucinous neoplasms (IPMNs)have a wide pathologic spectrum and it is difficult to differentiate malignant from benign tumors. The aim of this study was to identify predictors of malignancy using contrast-enhanced endoscopic ultrasound (CE-EUS).SUBJECTS AND METHODS: In our instit... | ['Adenocarcinoma, Mucinous', 'Aged', 'Aged, 80 and over', 'Analysis of Variance', 'Biopsy, Fine-Needle', 'Carcinoma, Pancreatic Ductal', 'Cohort Studies', 'Confidence Intervals', 'Contrast Media', 'Diagnosis, Differential', 'Endosonography', 'Female', 'Humans', 'Immunohistochemistry', 'Logistic Models', 'Male', 'Mucous... | 19,300,203 | [['C04.557.470.200.025.075', 'C04.557.470.590.075'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.1... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
microRNA and Metabolite Signatures Linked to Early Consequences of Lethal Radiation. | Lethal total body irradiation (TBI) triggers multifactorial health issues in a potentially short time frame. Hence, early signatures of TBI would be of great clinical value. Our study aimed to interrogate microRNA (miRNA) and metabolites, two biomolecules available in blood serum, in order to comprehend the immediate i... | ['Animals', 'Biomarkers', 'Dose-Response Relationship, Radiation', 'Fatty Acids', 'Gamma Rays', 'Inflammation', 'Male', 'Mass Spectrometry', 'Mice', 'MicroRNAs', 'Radiation Exposure', 'Reactive Oxygen Species', 'Whole-Body Irradiation'] | 32,214,144 | [['B01.050'], ['D23.101'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['D10.251'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['C23.550.470'], ['E05.196.566'], ['B01.050.150.900.649.313.992.635.505.500'], ['D13.150.650.319', 'D13.444.735.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Replacing Saturated Fats with Unsaturated Fats from Walnuts or Vegetable Oils Lowers Atherogenic Lipoprotein Classes Without Increasing Lipoprotein(a). | BACKGROUND: Walnuts have established lipid-/lipoprotein-lowering properties; however, their effect on lipoprotein subclasses has not been investigated. Furthermore, the mechanisms by which walnuts improve lipid/lipoprotein concentrations are incompletely understood.OBJECTIVES: We aimed to examine, as exploratory outcom... | ['Adult', 'Aged', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Cross-Over Studies', 'Diet', 'Fats, Unsaturated', 'Fatty Acids', 'Female', 'Food Analysis', 'Gene Expression Regulation', 'Humans', 'Juglans', 'Lipoprotein(a)', 'Male', 'Middle Aged', 'Overweight', 'Plant Oils', 'Proprotein Convertase 9'] | 31,909,809 | [['M01.060.116'], ['M01.060.116.100'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['G07.203.650.240'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Antigens of Micropolyspora faeni strains. | Exocellular antigens from Micropolyspora faeni and Micropolyspora rectivirgula were prepared by growing them in a synthetic broth culture at 50 degrees C for 1 week under continuous shaking. The broth was separated from the organisms by filtration and the filtrate was dialyzed and freeze-dried. The cross-reactivity of ... | ['Antibodies, Bacterial', 'Antigens, Bacterial', 'Epitopes', 'Immunoelectrophoresis, Two-Dimensional', 'Micromonosporaceae', 'Species Specificity'] | 89,093 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D23.050.161'], ['D23.050.550'], ['E01.370.225.812.735.645.350.350.350', 'E05.196.401.568.520', 'E05.200.812.735.645.350.350.350', 'E05.301.300.568.520', 'E05.478.594.760.645.350.350.350', 'E05.478.605.492.350.350.350'], ['... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Aberrant Behavior Checklist and the Behavior Problems Inventory: convergent and divergent validity. | This study was designed to compare and cross-validate two rating instruments [the Aberrant Behavior Checklist (ABC) and the Behavior Problems Inventory (BPI)] for assessing maladaptive behavior. The BPI assesses three types of behavior problems: Self-Injurious Behavior (SIB), Stereotyped Behavior and Aggressive/Destruc... | ['Adaptation, Psychological', 'Adult', 'Aged', 'Aged, 80 and over', 'Diagnosis, Differential', 'Female', 'Humans', 'Intellectual Disability', 'Male', 'Middle Aged', 'Regression Analysis', 'Reproducibility of Results', 'Self-Injurious Behavior', 'Severity of Illness Index', 'Stereotypic Movement Disorder', 'Surveys and ... | 12,951,135 | [['F01.058'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['M01.060.116.630'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['E05.318.370.725',... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The legendary contributions of Thomas Willis (1621-1675): the arterial circle and beyond. | Thomas Willis established neurology as a distinct discipline and made significant original contributions to many related fields including anatomy, pathology, cardiology, endocrinology, and gastroenterology. He is most remembered for his work in elucidating the function and anatomy of the circle of Willis. Willis' accom... | ['Brain Diseases', 'Circle of Willis', 'Cranial Nerves', 'England', 'History, 17th Century', 'Humans', 'Neuroanatomy', 'Neurology'] | 18,826,368 | [['C10.228.140'], ['A07.015.114.228.351'], ['A08.800.800.120'], ['Z01.542.363.300'], ['K01.400.504.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.158.100.700', 'H01.158.610.060'], ['H02.403.600']] | ['Diseases [C]', 'Anatomy [A]', 'Geographicals [Z]', 'Humanities [K]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Attempts to induce chronic experimental allergic neuritis in strain 13 and Hartley guinea pigs. | An attempt has been made to develop a model of chronic experimental allergic neuritis (EAN) using juvenile and adult inbred (Strain 13) and Hartley guinea pigs sensitized with peripheral nerve in complete Freund's adjuvant. Animals were followed clinically for periods ranging from 2 to 44 weeks postinoculation and then... | ['Age Factors', 'Animals', 'Autoimmune Diseases', 'Demyelinating Diseases', 'Disease Models, Animal', 'Guinea Pigs', 'Neuritis', 'Peripheral Nerves', 'Spinal Cord', 'Spinal Nerve Roots'] | 870,623 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['C20.111'], ['C10.314'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['B01.050.150.900.649.313.992.550'], ['C10.668.829.650'], ['A08.800.800'], ['A08.186.854'], ['A08.800.800.720.725']] | ['Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Striving for safety: experiences of nurses in a hospital under siege. | The hospital in which this study took place served as a centre for emergencies, critically ill patients and maternity cases during a nurses' strike in 98 hospitals in Alberta, Canada. Nurses at this hospital were not members of the striking union; they belonged to their own independent union and they worked throughout ... | ['Adaptation, Psychological', 'Alberta', 'Burnout, Professional', 'Clinical Competence', 'Female', 'Humans', 'Interviews as Topic', 'Leadership', 'Male', 'Morale', 'Nursing Methodology Research', 'Nursing Staff, Hospital', 'Quality of Health Care', 'Safety', 'Strikes, Employee', 'Workload'] | 1,578,072 | [['F01.058'], ['Z01.107.567.176.064'], ['C24.580.500', 'F01.145.126.990.367.500', 'F02.830.900.333.500'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['F01.752.609'], ['F01.829.4... | ['Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Named Groups [... | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Assessment of Tunisian acceptance to participate in a Clinical Trial. | "CT" clinical trials are medical research studies to determine whether different treatments are effective and safe. Some trials involve patients and other trials involve healthy volunteers. This survey aims to assess CT knowledge and the acceptance to participate to CT of Tunisian citizen. The study involved 260 partic... | ['Attitude of Health Personnel', 'Clinical Trials as Topic', 'Community Participation', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Patient Participation', 'Research Subjects', 'Surveys and Questionnaires', 'Tunisia'] | 31,729,700 | [['F01.100.050', 'N05.300.100'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['N02.421.143.212', 'N03.540.245.360'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.100.150.750.500.620', 'F01.145.488.887.500.620', 'N02.421.143.212.300', '... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Germline MEN1 mutations in sixteen Japanese families with multiple endocrine neoplasia type 1 (MEN1). | OBJECTIVE: Multiple endocrine neoplasia type 1 (MEN1) is a syndrome of endocrine tumors involving the parathyroids, anterior pituitary and enteropancreatic neuroendocrine tissues, and is inherited in an autosomal dominant manner. Recently, the gene responsible for this syndrome, MEN1, was positionally cloned in 11q13. ... | ['Adult', 'Aged', 'DNA', 'DNA Primers', 'Electrophoresis, Agar Gel', 'Electrophoresis, Polyacrylamide Gel', 'Female', 'Humans', 'Japan', 'Male', 'Middle Aged', 'Multiple Endocrine Neoplasia Type 1', 'Mutation', 'Neoplasm Proteins', 'Pancreatic Neoplasms', 'Parathyroid Neoplasms', 'Pituitary Neoplasms', 'Polymerase Chai... | 10,576,763 | [['M01.060.116'], ['M01.060.116.100'], ['D13.444.308'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['E05.196.401.153', 'E05.301.300.100'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['M01.060.116.630'], ['C04.588.322.400.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Communication activity in stroke patients with aphasia. | OBJECTIVE: To study communication disability in stroke patients with aphasia.PATIENTS AND METHODS: Prospective, multicentric cohort study of patients with aphasia, consecutively included after a first stroke, and examined 1 year later at home. Assessment included a stroke severity scale, the Barthel Index, the boston d... | ['Aged', 'Aphasia', 'Communication', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Recovery of Function', 'Severity of Illness Index', 'Stroke'] | 23,468,019 | [['M01.060.116.100'], ['C10.597.606.150.500.800.100', 'C23.888.592.604.150.500.800.100'], ['F01.145.209', 'L01.143'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['G16.757'], ['E05.318.308.980.438.475.45... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Long-term depression of NMDA receptor-mediated synaptic transmission is dependent on activation of metabotropic glutamate receptors and is altered to long-term potentiation by low intracellular calcium buffering. | Synaptic plasticity of NMDA receptor (NMDAR)-mediated transmission was investigated in the rat dentate gyrus in vitro. Isolated NMDAR EPSCs were recorded from granule cells of the dentate gyrus in response to stimulation of the medial perforant path. Long-term potentiation (LTP) or long-term depression (LTD) of NMDAR E... | ['2-Amino-5-phosphonovalerate', '6-Cyano-7-nitroquinoxaline-2,3-dione', 'Amino Acids', 'Animals', 'Buffers', 'Calcium', 'Dentate Gyrus', 'Egtazic Acid', 'Electric Stimulation', 'Excitatory Amino Acid Antagonists', 'Long-Term Synaptic Depression', 'Male', 'Patch-Clamp Techniques', 'Perforant Pathway', 'Pyridines', 'Rats... | 16,436,598 | [['D12.125.070.950.100', 'D12.125.740.025'], ['D03.633.100.857.160'], ['D12.125'], ['B01.050'], ['D27.720.470.280'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A08.186.211.180.405.200', 'A08.186.211.200.885.287.500.345.200'], ['D02.092.782.258.368.257', 'D02.241.081.018.269'], ['E05.723.402'], ['D27.505.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The control of Glossina morsitans morsitans (Diptera: Glossinidae) in a settled area in Petauke District (Eastern Province, Zambia) using odour-baited targets. | A trial to control G. m. morsitans with the use of 980 odour-baited, insecticide-impregnated targets was conducted in a 300 km2 area in the Eastern Province of Zambia between 1989 and 1991. The area is highly cultivated and cattle density is high (about 8 cattle/km2). Targets were deployed along roads and tracks. Deplo... | ['Animals', 'Antibodies, Protozoan', 'Cattle', 'Cattle Diseases', 'Insect Control', 'Insect Vectors', 'Odorants', 'Population Density', 'Seasons', 'Trypanosomiasis, African', 'Tsetse Flies', 'Zambia'] | 9,551,476 | [['B01.050'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['N06.850.780.200.650.425'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['G16.500.275.640', 'N06.230.480'], ['N01.224.600', 'N06.850.505.400... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
DNA barcoding of Aristolochia plants and development of species-specific multiplex PCR to aid HPTLC in ascertainment of Aristolochia herbal materials. | The anecdotal evidence is outstanding on the uses of Aristolochia plants as traditional medicines and dietary supplements in many regions of the world. However, herbal materials derived from Aristolochia species have been identified as potent human carcinogens since the first case of severe renal disease after ingestin... | ['Aristolochia', 'DNA Barcoding, Taxonomic', 'DNA, Plant', 'DNA, Ribosomal Spacer', 'Europe', 'Multiplex Polymerase Chain Reaction', 'Plant Preparations', 'Species Specificity', 'Thailand'] | 30,125,304 | [['B01.650.940.800.575.912.250.096.211'], ['E05.393.542.249', 'E05.393.760.700.149'], ['D13.444.308.435'], ['D13.444.308.324.230', 'D13.444.308.475.230'], ['Z01.542'], ['E05.393.620.500.487'], ['D20.215.784'], ['G16.824'], ['Z01.252.145.841']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Serotonin in human tears. | It has been postulated that serotonergic receptors are present in the corneal epithelium and that their activation by serotonin released from subepithelial corneal nerves raises the level of cyclic AMP, which in turn stimulates active CI-secretion by the corneal epithelium. We looked for serotonin in tears because thes... | ['Adolescent', 'Adult', 'Chromatography, High Pressure Liquid', 'Cornea', 'Epithelium', 'Female', 'Humans', 'Male', 'Middle Aged', 'Receptors, Serotonin', 'Serotonin', 'Tears'] | 7,819,731 | [['M01.060.057'], ['M01.060.116'], ['E05.196.181.400.300'], ['A09.371.060.217'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D12.776.543.750.670.800', 'D12.776.543.750.695.800', 'D12.776.543.750.720.850'], ['D02.092.211.215.801.852', 'D03.633.100.473.914.814', 'D23.469.050.650']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The use of hospital registries in orthopaedic surgery. | A hospital registry is a collection of prospectively recorded information about patients who have a specific condition or who received a specific type of treatment. Hospital registries are beneficial for the patient, physicians, and administrators and serve several purposes, with the primary purpose being quality contr... | ['Data Collection', 'Hospitals', 'Humans', 'Orthopedics', 'Quality Control', 'Registries', 'Research Design'] | 19,411,502 | [['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.810.494'], ['J01.897.608'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.300.715.700', 'N06.850.520.308.970'], ['E05.581.500', 'H01.770.644.728']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Stem cell factor in human seminal plasma as a marker for spermatogenesis. | OBJECTIVES: To measure the level of stem cell factor (SCF) in human seminal plasma to determine whether SCF may be useful in evaluating the ability to produce sperm and search the role of SCF in the testes.METHODS: We measured the level of SCF in seminal plasma obtained from 108 males, including idiopathic azoospermia ... | ['Humans', 'Male', 'Oligospermia', 'RNA, Messenger', 'Semen', 'Spermatogenesis', 'Stem Cell Factor'] | 9,510,353 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365.700.508'], ['D13.444.735.544'], ['A12.200.732'], ['G04.152.650.624', 'G08.686.784.310.760'], ['D12.644.276.374.410.800', 'D12.776.467.374.410.800', 'D23.529.374.410.800']] | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CD24 Is Not Required for Tumor Initiation and Growth in Murine Breast and Prostate Cancer Models. | CD24 is a small, heavily glycosylated, GPI-linked membrane protein, whose expression has been associated with the tumorigenesis and progression of several types of cancer. Here, we studied the expression of CD24 in tumors of MMTV-PyMT, Apc1572/T+ and TRAMP genetic mouse models that spontaneously develop mammary or pros... | ['Animals', 'CD24 Antigen', 'Cell Differentiation', 'Cell Transformation, Neoplastic', 'Female', 'Gene Expression Regulation, Developmental', 'Gene Expression Regulation, Neoplastic', 'Genes, APC', 'Male', 'Mammary Glands, Animal', 'Mammary Neoplasms, Experimental', 'Mammary Tumor Virus, Mouse', 'Mice', 'Mice, Inbred C... | 26,978,528 | [['B01.050'], ['D12.776.395.550.200.098', 'D12.776.395.550.448.120', 'D12.776.543.484.500.120', 'D12.776.543.550.200.124', 'D12.776.543.550.418.120', 'D23.050.285.018', 'D23.050.301.350.098'], ['G04.152'], ['C04.697.098.500', 'C23.550.727.098.500'], ['G05.308.310'], ['G05.308.370'], ['G05.360.340.024.340.375.249.050', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization of Toxin Complex Gene Clusters and Insect Toxicity of Bacteria Representing Four Subgroups of Pseudomonas fluorescens. | Ten strains representing four lineages of the Pseudomonas fluorescens group (P. chlororaphis, P. corrugata, P. koreensis, and P. fluorescens subgroups) were evaluated for toxicity to the tobacco hornworm Manduca sexta and the common fruit fly Drosophila melanogaster. The three strains within the P. chlororaphis subgrou... | ['Animals', 'Bacterial Proteins', 'Bacterial Toxins', 'Drosophila melanogaster', 'Manduca', 'Multigene Family', 'Pseudomonas fluorescens'] | 27,580,176 | [['B01.050'], ['D12.776.097'], ['D23.946.123'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['B01.050.500.131.617.720.500.500.937.650.525'], ['G05.360.340.024.340.645'], ['B03.440.400.425.625.625.325', 'B03.660.250.580.590.210']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Locked metacarpo-phalangeal joint of the thumb. | 16 patients developed locking of the M.P. joint of the thumb as the result of a hyperextension injury. Four were successfully treated by manipulation under an intra-articular injection of a local anaesthetic, while the remaining twelve required open reduction. All were examined 4 to 48 months after treatment (average 1... | ['Adolescent', 'Adult', 'Child', 'Female', 'Finger Injuries', 'Humans', 'Joint Dislocations', 'Male', 'Metacarpophalangeal Joint', 'Middle Aged', 'Thumb'] | 3,249,154 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['C26.448.429'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['A02.835.583.405.500'], ['M01.060.116.630'], ['A01.378.800.667.430.705']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Intrathoracic sarcoidosis associated with tuberculous spondylodiscitis. 2 cases]. | We report 2 cases of intrathoracic sarcoidosis associated with tuberculous spondylitis. Although such cases are exceptional, one cannot help wondering whether or not sarcoidosis and tuberculosis are interrelated. | ['Adult', 'Discitis', 'Humans', 'Lumbar Vertebrae', 'Lung Diseases', 'Magnetic Resonance Imaging', 'Male', 'Mediastinal Diseases', 'Radiography, Thoracic', 'Sarcoidosis', 'Thoracic Vertebrae', 'Tomography, X-Ray Computed', 'Tuberculosis, Osteoarticular'] | 2,371,478 | [['M01.060.116'], ['C01.160.762.301', 'C05.116.165.762.301', 'C05.116.900.853.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['C08.381'], ['E01.370.350.825.500'], ['C08.846.187'], ['E01.370.350.700.730'], ['C15.604.515.827'], ['A02.835.232.834.892'], ['E01.370.350.350.810', 'E01.370.35... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Transcriptional modules related to hepatocellular carcinoma survival: coexpression network analysis. | We performed weighted gene coexpression network analysis (WGCNA) to gain insights into the molecular aspects of hepatocellular carcinoma (HCC). Raw microarray datasets (including 488 samples) were downloaded from the Gene Expression Omnibus (GEO) website. Data were normalized using the RMA algorithm. We utilized the WG... | ['Algorithms', 'Carcinoma, Hepatocellular', 'Gene Expression Profiling', 'Gene Regulatory Networks', 'Humans', 'Liver Neoplasms', 'Oligonucleotide Array Sequence Analysis', 'Prognosis', 'Regression Analysis'] | 27,052,251 | [['G17.035', 'L01.224.050'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E05.393.332'], ['G05.360.080.689.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Aspirin and Non-Aspirin NSAID Use and Prostate Cancer Incidence, Mortality, and Case Fatality in the Atherosclerosis Risk in Communities Study. | BACKGROUND: NSAIDs appear to moderately reduce prostate cancer risk. However, evidence is limited on whether NSAIDs protect against prostate cancer mortality (death from prostate cancer among men without a cancer history) and case fatality (death from prostate cancer among men with prostate cancer), and whether benefit... | ['Anti-Inflammatory Agents, Non-Steroidal', 'Aspirin', 'Atherosclerosis', 'Ethnic Groups', 'Follow-Up Studies', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Prognosis', 'Prospective Studies', 'Prostatic Neoplasms', 'Risk Assessment', 'Survival Rate', 'United States'] | 30,487,131 | [['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D02.455.426.559.389.657.410.595.176'], ['C14.907.137.126.307'], ['M01.686.754', 'N01.224.317'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Quantitative studies on the polarization optical properties of striated muscle. I. Birefringence changes of rabbit psoas muscle in the transition from rigor to relaxed state. | The changes in birefringence in the rigor to relax transition of single triton-extracted rabbit psoas muscle fibers have been investigated with quantitative polarized light techniques. The total birefringence of rest lenght fibers in rigor was (1.46 +/- 0.08) x 10(-3) and increased to (1.67 +/- 0.05) x 10(-3) after Mg-... | ['Adenosine Triphosphate', 'Animals', 'Birefringence', 'Hydrogen-Ion Concentration', 'Muscle Contraction', 'Muscles', 'Myofibrils', 'Myosins', 'Osmolar Concentration', 'Rabbits'] | 16,016 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['G01.590.080'], ['G02.300'], ['G11.427.494'], ['A02.633', 'A10.690'], ['A10.690.552.875', 'A11.284.430.214.190.750.620', 'A11.620.249.850', 'A11.620.500.500'], ['D05.750.078.730.475', 'D08.811.277.040.025.193.750', 'D12.776.21... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunogenicity of Semliki Forest virus based self-amplifying RNA expressing Indian HIV-1C genes in mice. | Development of recombinant vaccines is considered as a promising approach to prevent transmission and eradication of HIV/AIDS. Candidate vaccines tested so far have shown poor to modest efficacy. Self-amplifying RNAs of positive strand alphaviruses are reported to be promising vectors for development of recombinant vac... | ['AIDS Vaccines', 'Animals', 'Cell Line', 'Cricetinae', 'Cytokines', 'Gene Expression', 'Gene Expression Regulation, Viral', 'Gene Order', 'Genetic Vectors', 'Genotype', 'HIV-1', 'Humans', 'Immunity, Cellular', 'Immunity, Humoral', 'Immunization', 'Mice', 'RNA, Viral', 'Semliki forest virus', 'Vaccines, DNA', 'env Gene... | 26,361,864 | [['D20.215.894.899.050'], ['B01.050'], ['A11.251.210'], ['B01.050.150.900.649.313.992.635.075.250'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G05.297'], ['G05.308.385'], ['G05.340'], ['G05.360.337'], ['G05.380'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Neuron-specific Cdk5 kinase is responsible for mitosis-independent phosphorylation of c-Src at Ser75 in human Y79 retinoblastoma cells. | c-Src is phosphorylated at specific serine and threonine residues during mitosis in fibroblastic and epithelial cells. These sites are phosphorylated in vitro by the mitotic kinase Cdk1 (p34(cdc2)). In contrast, c-Src in Y79 human retinoblastoma cells, which are of neuronal origin, is phosphorylated at one of the mitot... | ['4-Butyrolactone', 'Binding Sites', 'CSK Tyrosine-Protein Kinase', 'Cyclin-Dependent Kinase 5', 'Cyclin-Dependent Kinases', 'DNA, Antisense', 'Enzyme Inhibitors', 'Humans', 'Mitosis', 'Neurons', 'Phosphorylation', 'Protein-Tyrosine Kinases', 'Retinoblastoma', 'Serine', 'Transfection', 'Tumor Cells, Cultured', 'src-Fam... | 10,544,291 | [['D02.540.150', 'D03.383.312.150'], ['G02.111.570.120'], ['D08.811.913.696.620.682.725.800.158'], ['D08.811.913.696.620.682.700.646.500.500.500', 'D12.644.360.250.067.875', 'D12.776.167.200.067.875', 'D12.776.476.250.067.875'], ['D08.811.913.696.620.682.700.646.500', 'D12.644.360.250', 'D12.776.167.200', 'D12.776.476.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Multimodal imaging of language reorganization in patients with left temporal lobe epilepsy. | This study explored the relationships among multimodal imaging, clinical features, and language impairment in patients with left temporal lobe epilepsy (LTLE). Fourteen patients with LTLE and 26 controls underwent structural MRI, functional MRI, diffusion tensor imaging, and neuropsychological language tasks. Lateralit... | ['Adult', 'Anisotropy', 'Brain Mapping', 'Cerebral Cortex', 'Diffusion Tensor Imaging', 'Epilepsy, Temporal Lobe', 'Female', 'Functional Laterality', 'Humans', 'Language', 'Language Disorders', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Multimodal Imaging', 'Nerve Net', 'Neuropsychological Tests', 'Temporal ... | 28,432,987 | [['M01.060.116'], ['G01.590.040', 'G02.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.500'], ['E01.370.350.578.750', 'E01.370.350.825.500.150.500', 'E01.370.376.537.500', 'E05.629.750'], ['C10.228.140.490.360.290', 'C10.228.140.490.493.375'], ['F02.830.297.42... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Maur?cio Rocha e Silva MD: snake venom, bradykinin and the rise of autopharmacology. | Maur?cio Rocha e Silva is well known as the discoverer of bradykinin, the powerful hypotensive and smooth muscle stimulating polypeptide which was first detected in plasma following the addition of Bothrops jararaca venom. The discovery in S?o Paulo, Brazil, in 1948 was the outcome of studies on proteolytic enzymes tha... | ['Biochemistry', 'Bradykinin', 'Brazil', 'History, 20th Century', 'Snake Venoms'] | 9,428,104 | [['H01.158.201', 'H01.181.122'], ['D12.644.276.812.169', 'D12.644.400.090', 'D12.644.456.193', 'D12.776.467.812.169', 'D12.776.631.650.090', 'D23.469.050.375.110', 'D23.529.812.169'], ['Z01.107.757.176'], ['K01.400.504.968'], ['D20.888.850', 'D23.946.833.850']] | ['Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Humanities [K]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
A longitudinal study of the relationship between lifestyle and mental health among midlife and older women in Australia: findings from the Healthy Aging of Women Study. | We investigated the temporal relationship between lifestyle and mental health among 564 midlife women. The mental health measured included anxiety, depression, and mental well-being; the lifestyle measures included body mass index (BMI), exercise, smoking, alcohol use, and caffeine consumption. We found that BMI was po... | ['Aging', 'Alcohol Drinking', 'Anxiety', 'Australia', 'Body Mass Index', 'Depression', 'Exercise', 'Female', 'Humans', 'Life Style', 'Mental Disorders', 'Mental Health', 'Middle Aged', 'Prospective Studies', 'Psychiatric Status Rating Scales', 'Smoking', 'Socioeconomic Factors'] | 21,058,092 | [['G07.345.124'], ['F01.145.317.269'], ['F01.470.132'], ['Z01.639.100', 'Z01.678.100.373'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['F01.145.126.350'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458'], ['F03'], ['... | ['Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Human cell engraftment after busulfan or irradiation conditioning of NOD/SCID mice. | Human hematopoietic stem cell (HSC) xenotransplantation in NOD/SCID mice requires recipient conditioning, classically achieved by sublethal irradiation. Pretreatment with immunosuppressive and alkylating agents has been reported, but has not been rigorously tested against standard irradiation protocols. Here, we report... | ['Animals', 'Busulfan', 'Gamma Rays', 'Graft Rejection', 'Humans', 'Mice', 'Mice, Inbred NOD', 'Mice, SCID', 'Stem Cell Transplantation', 'Transplantation Conditioning', 'Transplantation, Heterologous'] | 17,018,389 | [['B01.050'], ['D02.033.455.125.125', 'D02.455.326.146.100.050.500.100', 'D02.886.645.600.055.050.510.100'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.565', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The forkhead transcription factor FOXL2 is expressed in somatic cells of the human ovary prior to follicle formation. | Interactions between germ cells and surrounding somatic cells are central to ovarian development as well as later function. Disruption of these interactions arising from abnormalities in either cell type can lead to premature ovarian failure (POF). The forkhead transcription factor FOXL2 is a candidate POF factor, and ... | ['Activins', 'Adult', 'Animals', 'Female', 'Fetus', 'Forkhead Box Protein L2', 'Forkhead Transcription Factors', 'Gene Expression Regulation, Developmental', 'Humans', 'Male', 'Mice', 'Ovarian Follicle', 'Ovary', 'Pregnancy', 'Primary Ovarian Insufficiency', 'RNA, Messenger'] | 19,706,741 | [['D06.472.334.500', 'D06.472.699.009', 'D12.644.548.009', 'D12.776.395.022'], ['M01.060.116'], ['B01.050'], ['A16.378'], ['D12.776.260.950.249.032', 'D12.776.930.977.249.032'], ['D12.776.260.950.249', 'D12.776.930.977.249'], ['G05.308.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.99... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Surfactants-aided syntheses of different sizes and triangular shape of gold nanoparticles using trisodium citrate in environmentally friendly and photoinduced methods. | We prepared gold nanoparticles (Au NPs) by only using trisodium citrate as the stabilizer. The detailed reaction mechanisms of S(N)1 and E1 reactions are examined and evidenced in this study by FTIR data. Citric acid is a kind of tertiary substrate. In aqueous solution, the substitution nucleophile path 1 (S(N)1) react... | ['Adsorption', 'Chlorides', 'Citrates', 'Environment', 'Gold', 'Ions', 'Light', 'Metal Nanoparticles', 'Microscopy, Electron, Transmission', 'Nanotechnology', 'Photochemistry', 'Spectrophotometry, Ultraviolet', 'Spectroscopy, Fourier Transform Infrared', 'Surface Properties', 'Surface-Active Agents'] | 18,019,141 | [['G01.030', 'G02.020'], ['D01.210.450.150', 'D01.248.497.158.215'], ['D02.241.081.901.434'], ['G16.500.275', 'N06.230'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['D01.248.497'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['J01.637.512.600.500'], ['E01.370.350.515.4... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Pilot study of 19 patients with severe pemphigus: prophylactic treatment with rituximab does not appear to be beneficial. | AIMS: To assess the efficacy and safety of rituximab in refractory pemphigus and the possible benefit of an additional prophylactic infusion at 6 months.METHODS: Seventeen patients with pemphigus vulgaris, 1 with pemphigus foliaceus and 1 with pemphigus vegetans were treated with 4 weekly infusions of rituximab (375 mg... | ['Adult', 'Aged', 'Antibodies, Monoclonal, Murine-Derived', 'Dermatology', 'Female', 'Hospitals, University', 'Humans', 'Immunologic Factors', 'Infusion Pumps', 'Male', 'Middle Aged', 'Pemphigus', 'Pilot Projects', 'Prospective Studies', 'Recurrence', 'Rituximab', 'Treatment Failure', 'Treatment Outcome'] | 24,557,145 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.224.075', 'D12.776.124.790.651.114.224.075', 'D12.776.377.715.548.114.224.284'], ['H02.403.225'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477'], ['E07.505', 'E07.858.082.505'], ['M01.0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis and evaluation of cis-hexahydropyrrolo[3,2-b]pyrrol-3-one peptidomimetic inhibitors of CAC1 cysteinyl proteinases. | A stereoselective synthesis of functionalised cis-hexahydropyrrolo[3,2-b]pyrrol-3-ones has been developed through Fmoc and Cbz-protected intermediates 5 and 6. Building blocks 5 and 6 were prepared via the intramolecular cyclisation of anti-epoxide 17. The intramolecular reaction occurred exclusively through the anti-e... | ['Chromatography, High Pressure Liquid', 'Cysteine Proteinase Inhibitors', 'Humans', 'Molecular Mimicry', 'Osteoblasts', 'Pyrroles', 'Spectrum Analysis'] | 15,653,329 | [['E05.196.181.400.300'], ['D27.505.519.389.745.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.560', 'G05.545', 'G16.012.750.500'], ['A11.329.629'], ['D03.383.129.578'], ['E05.196.867']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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