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Rare chromosomal aberrations induced by vincristine. Partial endoreduplication and pseudoendoreduplication, segmentally endoreduplicated chromosomes, and segmental premature chromosome condensation.
Vincristine (VCR) is capable of inducing a cell containing both conventional chromosomes (monochromosomes) and diplochromosomes. A total of 124 such metaphases were examined by 5-bromodeoxyuridine (BrdU) incorporation and fluorescence plus Giemsa (FPG) technique to analyze cell cycle kinetics. The majority of cells (11...
['Aneuploidy', 'Animals', 'Autoradiography', 'Cells, Cultured', 'Chromosome Aberrations', 'Cricetinae', 'DNA Replication', 'In Vitro Techniques', 'Polyploidy', 'Vincristine']
1,993,301
[['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['A11.251'], ['C23.550.210', 'G05.365.590.175'], ['B01.050.150.900.649.313.992.635.075.250'], ['G02.111.225', 'G05.226'], ['E05.481'], ['C23.550.210.702', 'G05.365.590.175.677', 'G05.700.7...
['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]']
1
1
1
1
1
0
1
0
0
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Aorta-pulmonary shunts in growing pigs. Functional and structural assessment of the changes in the pulmonary circulation.
Aorta-pulmonary shunts were produced in growing pigs, 4 to 12 weeks of age, by anastomosing the thoracic descending aorta to the pulmonary trunk, and the animals were followed for periods of 1 to 3 months. Correlation between the hemodynamic findings and the lung structure, analyzed by quantitative methods, showed that...
['Animals', 'Aorta, Thoracic', 'Cardiac Catheterization', 'Female', 'Follow-Up Studies', 'Lung', 'Male', 'Methods', 'Pulmonary Artery', 'Pulmonary Circulation', 'Respiration', 'Swine']
758,561
[]
[]
0
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Peripheral blood myeloid-derived suppressor cells reflect disease status in idiopathic pulmonary fibrosis.
Idiopathic pulmonary fibrosis (IPF) is a fibroproliferative disease with irreversible lung function loss and poor survival. Myeloid-derived suppressor cells (MDSC) are associated with poor prognosis in cancer, facilitating immune evasion. The abundance and function of MDSC in IPF is currently unknown.Fluorescence-activ...
['Aged', 'Biomarkers', 'Case-Control Studies', 'Cell Separation', 'Coculture Techniques', 'Disease Progression', 'Female', 'Flow Cytometry', 'Humans', 'Idiopathic Pulmonary Fibrosis', 'Immune System', 'Leukocytes, Mononuclear', 'Lung', 'Lung Diseases, Interstitial', 'Male', 'Middle Aged', 'Myeloid-Derived Suppressor Ce...
27,587,556
[['M01.060.116.100'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E05.481.500.374'], ['C23.550.291.656'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.34...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]']
1
1
1
1
1
0
0
0
0
0
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1
1
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Incidence of type 2 diabetes by place of birth in the Multi-Ethnic Study of Atherosclerosis (MESA).
Incidence of diabetes among US foreign-born individuals is not well studied. Data were from the Multi Ethnic Study of Atherosclerosis. Cox proportional hazards regression was used to examine diabetes risk by race/ethnicity, place of birth, and duration of residence among foreign-born. Foreign-born Latinos had a higher ...
['African Continental Ancestry Group', 'Aged', 'Aged, 80 and over', 'Atherosclerosis', 'China', 'Cohort Studies', 'Confidence Intervals', 'Diabetes Mellitus, Type 2', 'Emigrants and Immigrants', 'European Continental Ancestry Group', 'Female', 'Hispanic Americans', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Proport...
22,833,256
[['M01.686.508.100'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.137.126.307'], ['Z01.252.474.164'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['C18.452.394.750.149', 'C19.246.300'], ['M01.189'], ['M01.6...
['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]']
0
1
1
0
1
0
0
0
0
0
0
1
1
1
DNA (cytosine-5) methyltransferase turnover and cellular localization in developing Paracentrotus lividus sea urchin embryo.
The turnover and localization of the enzyme DNA (cytosine-5) methyltransferase (Dnmt1) were studied during Paracentrotus lividus sea urchin embryo development using antibody preparations against the NH(2) and COOH-terminal regions of the molecule. The antibodies reveal, by Western blots and whole-mount analyses, that t...
['Animals', 'Antibodies, Monoclonal', 'Antibody Specificity', 'Blotting, Western', 'DNA', 'DNA (Cytosine-5-)-Methyltransferases', 'Embryo, Nonmammalian', 'Embryonic Development', 'Isoenzymes', 'Molecular Weight', 'Precipitin Tests', 'Sea Urchins', 'Substrate Specificity']
11,470,526
[['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D13.444.308'], ['D08.811.913.555.500.350.100.500'], ['A13.350', 'A16.331'], ['G07.345.500.325.1...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]']
1
1
0
1
1
0
1
0
0
0
0
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Lack of synergy by mixtures of weakly estrogenic hydroxylated polychlorinated biphenyls and pesticides.
We examined the estrogenicity of binary mixtures of the hydroxylated polychlorinated biphenyls (OHPCBs) 2,4,6-trichloro-4'-biphenylol (2,4,6-TCB-4'-OH) and 2,3,4,5-tetrachloro-4'-biphenylol and the pesticides endosulfan and dieldrin. The OHPCBs and pesticides were tested in both the MCF-7 focus assay and a competitive ...
['Adenocarcinoma', 'Binding, Competitive', 'Breast Neoplasms', 'Dieldrin', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Endosulfan', 'Estrogens', 'Female', 'Humans', 'Insecticides', 'Polychlorinated Biphenyls', 'Receptors, Estrogen', 'Tumor Cells, Cultured']
9,703,490
[['C04.557.470.200.025'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['C04.588.180', 'C17.800.090.500'], ['D02.455.526.439.371'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['D02.886.092.408', 'D03.633.100.197.408'], ['D27.505.696.399.472.277'], ['B01.050.150.900.649.313.988.400.112.400.40...
['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]']
1
1
1
1
1
0
1
0
0
0
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Strong linkage disequilibrium of TAP1*0301 and TAP2D alleles with the HLA A1-B35-DRB1*1104-DQA1*0103-DQB1*0603 extended haplotype in Ashkenazi Jews.
On the basis of data collected during the 12th International Histocompatibility Workshop, we postulated a possible linkage disequilibrium between the TAP1C allele and the DRB1*1104-DQA1*0103-DQB1*0603 haplotype characteristic of Ashkenazi Jews. In order to confirm and extend this preliminary observation, a group of 34 ...
['ATP Binding Cassette Transporter, Subfamily B, Member 2', 'ATP Binding Cassette Transporter, Subfamily B, Member 3', 'ATP-Binding Cassette Transporters', 'Alleles', 'Female', 'Genotype', 'HLA-DQ Antigens', 'HLA-DQ alpha-Chains', 'HLA-DQ beta-Chains', 'HLA-DR Antigens', 'HLA-DRB1 Chains', 'Haplotypes', 'Humans', 'Jews...
10,553,498
[['D12.776.157.530.100.075.250', 'D12.776.157.530.450.074.500.500.250.250', 'D12.776.395.550.020.400.305', 'D12.776.543.550.192.400.305', 'D12.776.543.585.100.200.250', 'D12.776.543.585.450.074.500.500.250.250'], ['D12.776.157.530.100.075.500', 'D12.776.157.530.450.074.500.500.250.375', 'D12.776.395.550.020.400.458', '...
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
0
1
1
0
1
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0
0
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1
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The effect of methylene blue phototreatment on plasma proteins and in vitro coagulation capability of single-donor fresh-frozen plasma.
BACKGROUND: Photodynamic virus inactivation of fresh-frozen plasma (FFP) may result in its impaired coagulation capability.STUDY DESIGN AND METHODS: Double-volume plasmapheresis samples from 11 donors were divided in pairs of 250 mL. One group underwent methylene blue (MB) phototreatment (MB-FFP). The other group was t...
['Blood Coagulation', 'Blood Proteins', 'Humans', 'In Vitro Techniques', 'Light', 'Methylene Blue', 'Plasma', 'Viruses']
8,073,485
[['G09.188.390.150'], ['D12.776.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['D02.886.369.517', 'D03.633.300.783.517'], ['A12.207.152.693', 'A12.207.270.695', 'A15.145.693'], ['B04']]
['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]']
1
1
0
1
1
0
1
0
0
0
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Identification of a calcium-controlled negative regulatory system affecting Vibrio cholerae biofilm formation.
Vibrio cholerae's capacity to cause outbreaks of cholera is linked to its survival and adaptability to changes in aquatic environments. One of the environmental conditions that can vary in V. cholerae's natural aquatic habitats is calcium (Ca(+2)). In this study, we investigated the response of V. cholerae to changes i...
['Biofilms', 'Calcium', 'Gene Expression Profiling', 'Gene Expression Regulation, Bacterial', 'Genes, Bacterial', 'Vibrio cholerae']
19,397,680
[['A20.593', 'G06.120'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.393.332'], ['G05.308.300'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['B03.440.450.900.859.225', 'B03.660.250.830.830.100']]
['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]']
1
1
0
1
1
0
1
0
0
0
0
0
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Seasonality of primary care utilization for respiratory diseases in Ontario: a time-series analysis.
BACKGROUND: Respiratory diseases represent a significant burden in primary care. Determining the temporal variation of the overall burden of respiratory diseases on the health care system and their potential causes are keys to understanding disease dynamics in populations and can contribute to the rational management o...
['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Child, Preschool', 'Cross-Sectional Studies', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Middle Aged', 'Models, Statistical', 'Multivariate Analysis', 'Ontario', 'Primary Health Care', 'Respiratory Tract Diseases', 'Retrospective S...
18,662,391
[['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'...
['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Phenomena and Processes [G]']
0
1
1
0
1
0
1
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1
1
Role of inhibitory control in modulating focal seizure spread.
Focal seizure propagation is classically thought to be spatially contiguous. However, distribution of seizures through a large-scale epileptic network has been theorized. Here, we used a multielectrode array, wide field calcium imaging, and two-photon calcium imaging to study focal seizure propagation pathways in an ac...
['4-Aminopyridine', 'Animals', 'Calcium', 'Electric Stimulation', 'Electroencephalography', 'Epilepsy', 'Interneurons', 'Male', 'Nerve Net', 'Neural Pathways', 'Neurons', 'Rats', 'Rats, Sprague-Dawley', 'Seizures', 'Synaptic Transmission']
29,757,347
[['D02.092.080.060', 'D03.383.725.050.060'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.723.402'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['A08.675.358', 'A11.671.358'], ['A08.511'], ['A08.612'], ['A08.675', 'A11.671'], ['B01.050.150.900.649.313.992.635.505.700'], ['...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]']
1
1
1
1
1
0
1
0
0
0
0
0
0
0
Protein thermal stability, hydrogen bonds, and ion pairs.
Researchers in both academia and industry have expressed strong interest in comprehending the mechanisms responsible for enhancing the thermostability of proteins. Many and different structural principles have been postulated for the increased stability. Here, 16 families of proteins with different thermal stability we...
['Animals', 'Heating', 'Humans', 'Hydrogen Bonding', 'Ions', 'Protein Folding', 'Protein Structure, Secondary', 'Proteins', 'Solvents', 'Thermodynamics']
9,217,266
[['B01.050'], ['N06.230.150.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.282'], ['D01.248.497'], ['G01.154.651', 'G02.111.688'], ['G02.111.570.820.709.600'], ['D12.776'], ['D27.720.844'], ['G01.906']]
['Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]']
0
1
0
1
0
0
1
0
0
0
0
0
1
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Conservative treatment for anterior dislocation of the meniscus.
Anterior dislocation of the meniscus is classified as an internal derangement of the temporomandibular joint (TMI). The pathogenesis and clinical syndromes of anterior dislocation have been described fairly frequently. Conservative treatment for this painful, clicking joint is the treatment of choice. This article pres...
['Adult', 'Female', 'Humans', 'Joint Dislocations', 'Temporomandibular Joint Disorders']
1,289,165
[['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['C05.500.607.221.897', 'C05.550.905', 'C05.651.243.897', 'C07.320.610.291.897', 'C07.678']]
['Named Groups [M]', 'Organisms [B]', 'Diseases [C]']
0
1
1
0
0
0
0
0
0
0
0
1
0
0
Serum creatine kinase BB isoenzyme as a diagnostic aid in occult small cell lung cancer.
Four patients with metastatic small cell carcinoma of the lung who had initial chest x-rays that did not reveal the cancer showed striking elevations of serum creatine kinase BB isoenzyme, which suggested the diagnosis and directed the subsequent evaluation. Creatine kinase BB isoenzyme elevation with widespread small ...
['Aged', 'Carcinoma, Small Cell', 'Creatine Kinase', 'Diagnosis, Differential', 'Female', 'Humans', 'Isoenzymes', 'Lung', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Staging']
2,988,748
[['M01.060.116.100'], ['C04.557.470.200.380'], ['D08.811.913.696.640.150'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.348', 'D12.776.800.300'], ['A04.411'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['E01.789.625']]
['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]']
1
1
1
1
1
0
0
0
0
0
0
1
0
0
Morbid obesity in women is associated to a lower prevalence of thyroid nodules.
BACKGROUND: Few studies have recently showed functional and morphological changes of the thyroid gland in relation to obesity. To our knowledge, no data are available about the prevalence of thyroid nodules in female obese patients. The aim of this study was to investigate the prevalence of thyroid nodules in morbidly ...
['Adult', 'Body Mass Index', 'Case-Control Studies', 'Female', 'Humans', 'Italy', 'Obesity, Morbid', 'Prevalence', 'Risk Assessment', 'Risk Factors', 'Thyroid Nodule', 'Thyrotropin', 'Ultrasonography']
21,491,133
[['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['C18.654.726.500.700', 'C23.888.144.699.500.500', 'E01.370.600...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Chemicals and Drugs [D]']
0
1
1
1
1
0
1
0
0
0
0
1
1
1
[Infectious complications of surgically treatment pelvic fractures].
Based on case histories, the authors draw attention to important infectious complications in patients surgically treated for pelvic injuries. These complications were recorded in four out of 75 patients (5.3%) undergoing surgery for pelvic fracture in the period from 2001 to 2005. The chief risk factors for the develop...
['Adult', 'Female', 'Fractures, Bone', 'Humans', 'Male', 'Pelvic Bones', 'Surgical Wound Infection']
18,760,086
[['M01.060.116'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.043.825'], ['C01.947.692', 'C23.550.767.925']]
['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]']
1
1
1
0
0
0
0
0
0
0
0
1
0
0
The nature of iron released by resident and stimulated mouse peritoneal macrophages.
Mouse peritoneal macrophages were allowed to ingest 59Fe, 125I-labelled transferrin-antitransferrin immune complexes, and the release of 59Fe and degraded transferrin was studied. Some iron was released as ferritin, but a major portion was bound by bovine transferrin present in the culture medium, which contained fetal...
['Animals', 'Antigen-Antibody Complex', 'Ascitic Fluid', 'Cells, Cultured', 'Ferritins', 'Iodine Radioisotopes', 'Iron', 'Iron Radioisotopes', 'Macrophages', 'Mice', 'Transferrin']
6,692,005
[['B01.050'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['A12.207.119'], ['A11.251'], ['D12.776.157.427.249', 'D12.776.556.579.249'], ['D01.268.380.400.500.496', 'D01.496.448.496', 'D01.496.749.474'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]']
1
1
0
1
0
0
0
0
0
0
0
0
0
0
[Effect of temperature on the infectivity of the iridovirus and densonucleosis virus of blood-sucking mosquitoes].
Mosquito densonucleosis virus and iridovirus were used to study the influence of temperature on their infectivity. Biological assays of mosquito densonucleosis virus were carried out in larvae of I-II instar of Aedes aegypti mosquitoes, those of mosquito iridovirus in larvae of Galleria mellonella. The rate of inactiva...
['Aedes', 'Animals', 'Culicidae', 'DNA Viruses', 'Insect Viruses', 'Iridoviridae', 'Larva', 'Temperature', 'Time Factors', 'Virus Activation']
2,905,849
[['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875'], ['B04.280'], ['B04.525'], ['B04.280.410'], ['B05.500.500', 'G07.345.500.550.500.500'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710...
['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]']
0
1
0
0
0
0
1
0
0
0
0
0
1
0
Is platelet transfusion efficient to restore platelet reactivity in patients who are responders to aspirin and/or clopidogrel before emergency surgery?
PURPOSE: The aim of this study was to confirm that emergency platelet transfusion effectively restores platelet function to patients receiving antiplatelet therapy (APT) with aspirin and/or clopidogrel.PATIENTS AND METHODS: This was a prospective observational case report series conducted between January 1, 2009, and J...
['Aspirin', 'Blood Platelets', 'Clopidogrel', 'Hemorrhage', 'Humans', 'Platelet Aggregation', 'Platelet Aggregation Inhibitors', 'Platelet Transfusion', 'Prospective Studies', 'Ticlopidine', 'Wounds and Injuries']
23,609,292
[['D02.455.426.559.389.657.410.595.176'], ['A11.118.188', 'A15.145.229.188'], ['D02.886.778.823.500.500', 'D03.383.725.849.500.500', 'D03.383.903.830.500.500', 'D03.633.100.928.500.500'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.188.370.687', 'G09.188.390.600.640'], ['D27.505.954.502.780'...
['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
1
1
1
1
1
0
1
0
0
0
0
0
1
0
Lansoprazole treatment of patients with chronic idiopathic laryngitis: a placebo-controlled trial.
OBJECTIVE: Previous uncontrolled studies suggested a therapeutic benefit for treating gastroesophageal reflux disease (GERD) among patients with laryngitis. The present study is the first randomized, placebo-controlled, double-blind study of gastric acid suppression among patients with laryngitis in the United States.M...
['2-Pyridinylmethylsulfinylbenzimidazoles', 'Aged', 'Chronic Disease', 'Double-Blind Method', 'Female', 'Gastroesophageal Reflux', 'Humans', 'Lansoprazole', 'Laryngitis', 'Male', 'Middle Aged', 'Omeprazole', 'Proton Pump Inhibitors']
11,316,215
[['D02.886.640.074', 'D03.383.725.024', 'D03.633.100.103.034'], ['M01.060.116.100'], ['C23.550.291.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.886.640.074.249', 'D03.383.725.024.249', 'D0...
['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]']
0
1
1
1
1
0
0
0
0
0
0
1
1
0
The effect of 1% chlorhexidine gel and 0.12% dentifrice gel on plaque accumulation: a 3-day non-brushing model.
AIM: The purpose of the study was to compare the effects of four treatments on 'de novo' plaque accumulation. Treatments included tray application of 1% chlorhexidine gel (CHX-Gel), 0.12% chlorhexidine dentifrice-gel (CHX-DFG), a regular dentifrice (RDF) tray application, or 0.2% chlorhexidine mouthwash (CHX-MW) in a 3...
['Analysis of Variance', 'Anti-Infective Agents, Local', 'Chlorhexidine', 'Dental Devices, Home Care', 'Dental Plaque', 'Dental Plaque Index', 'Dentifrices', 'Dose-Response Relationship, Drug', 'Female', 'Gels', 'Humans', 'Male', 'Mouthwashes', 'Periodontal Index', 'Single-Blind Method', 'Statistics, Nonparametric', 'S...
20,961,386
[['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D27.505.954.122.187'], ['D02.078.370.141.100'], ['E06.186.250', 'E06.761.726.292', 'E07.222.250'], ['C07.793.208.377'], ['E05.318.308.980.438.300.300', 'E06.208.250', 'N05.715.360.300.800.438.300.325', 'N06.850.520.308.980.438.300.300', 'N06.890.160....
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Named Groups [M]']
0
1
1
1
1
1
1
0
0
1
0
1
1
0
Prediction of Peptide and Protein Propensity for Amyloid Formation.
Understanding which peptides and proteins have the potential to undergo amyloid formation and what driving forces are responsible for amyloid-like fiber formation and stabilization remains limited. This is mainly because proteins that can undergo structural changes, which lead to amyloid formation, are quite diverse an...
['Amino Acid Sequence', 'Amyloid', 'Amyloidogenic Proteins', 'Neural Networks, Computer', 'Protein Structure, Secondary']
26,241,652
[['G02.111.570.060', 'L01.453.245.667.060'], ['D05.500.049', 'D12.776.049'], ['D12.776.049.407'], ['G17.485', 'L01.224.050.375.605'], ['G02.111.570.820.709.600']]
['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]']
0
0
0
1
0
0
1
0
0
0
1
0
0
0
Genetic analysis of a unique bacteriocin, Smb, produced by Streptococcus mutans GS5.
A dipeptide lantibiotic, named Smb, in Streptococcus mutans GS5 was characterized by molecular genetic approaches. The Smb biosynthesis gene locus is encoded by a 9.5-kb region of chromosomal DNA and consists of seven genes in the order smbM1, -T, -F, -M2, -G, -A, -B. This operon is not present in some other strains of...
['Bacteriocins', 'Base Sequence', 'Blotting, Northern', 'DNA Primers', 'DNA Transposable Elements', 'Molecular Sequence Data', 'Mutagenesis', 'Operon', 'Plasmids', 'RNA, Bacterial', 'Reverse Transcriptase Polymerase Chain Reaction', 'Streptococcus mutans']
15,673,730
[['D12.776.097.151', 'D12.776.543.695.110'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.20...
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]']
0
1
0
1
1
0
1
0
0
0
1
0
0
0
Integrating HIV, syphilis, malaria and anaemia point-of-care testing (POCT) for antenatal care at dispensaries in western Kenya: discrete-event simulation modelling of operational impact.
BACKGROUND: Despite WHO advocating for an integrated approach to antenatal care (ANC), testing coverage for conditions other than HIV remains low and women are referred to distant laboratories for testing. Using point-of-care tests (POCTs) at peripheral dispensaries could improve access to testing and timely treatment....
['Adult', 'Anemia', 'Female', 'HIV Infections', 'Humans', 'Kenya', 'Malaria', 'Nurses', 'Point-of-Care Testing', 'Pregnancy', 'Pregnancy Complications', 'Prenatal Care', 'Prenatal Diagnosis', 'Referral and Consultation', 'Syphilis', 'Time Factors', 'Time and Motion Studies', 'Workload']
31,795,999
[['M01.060.116'], ['C15.378.071'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.058.290.120.400'], ['C01.610.752.530', 'C01.920.875'], ['M01.526.485.650', 'N02.360.650'], ['N04.590.874.5...
['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]']
0
1
1
0
1
1
1
0
1
0
0
1
1
1
Laparoscopic versus robotic hysterectomy in obese and extremely obese patients with endometrial cancer: A multi-institutional analysis.
OBJECTIVE: The aim of this study was to evaluate the surgical and oncological outcome of robotic surgical staging with hysterectomy (RH) plus or less pelvic and aortic lymphadenectomy, compared to the same procedures performed by laparoscopic surgery (LH) in obese patients (BMI?30 kg/m2) with endometrial cancer.MATERIA...
['Adult', 'Aged', 'Aged, 80 and over', 'Body Mass Index', 'Endometrial Neoplasms', 'Female', 'Humans', 'Hysterectomy', 'Italy', 'Laparoscopy', 'Length of Stay', 'Lymph Node Excision', 'Middle Aged', 'Obesity', 'Operative Time', 'Retrospective Studies', 'Robotic Surgical Procedures', 'Treatment Outcome']
30,245,146
[['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['Z01.542...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]']
0
1
1
0
1
0
1
0
0
1
0
1
1
1
Surface plasmon resonance for the label-free detection of Alzheimer's â-amyloid peptide aggregation.
Amyloid peptide oligomers and fibrils are studied as targets for therapy and diagnosis of Alzheimer's disease. They are usually detected by amyloid incubation, but such method is necessarily associated with Aâ1-42 depletion and dye binding or conjugation, which have a complex influence on fibril growth, provide informa...
['Alzheimer Disease', 'Amyloid beta-Peptides', 'Humans', 'Surface Plasmon Resonance']
26,558,762
[['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.890', 'E05.601.043.700']]
['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
1
1
1
1
0
0
0
0
0
0
0
0
In situ extracorporeal shock wave lithotripsy for primary ureteric calculi.
OBJECTIVE: To determine the efficacy of the Lithostar lithotriptor for the in situ treatment of primary ureteric stones.METHODS: We reviewed, retrospectively, our experience with 283 patients with primary ureteric stones treated with extracorporeal shock wave lithotripsy (ESWL) using the Lithostar lithotriptor. No atte...
['Adolescent', 'Adult', 'Aged', 'Body Weight', 'Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Humans', 'Hydronephrosis', 'Lithotripsy', 'Male', 'Middle Aged', 'Retrospective Studies', 'Sex Factors', 'Treatment Outcome', 'Ureteral Calculi']
8,197,642
[['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900....
['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]']
0
1
1
0
1
0
1
0
0
0
0
1
1
0
Measles Outbreak at a Privately Operated Detention Facility: Arizona, 2016.
BACKGROUND: We describe a measles outbreak and control measures implemented at a privately operated detention facility housing US Immigration and Customs Enforcement detainees in 2016.METHODS: Case-patients reported fever and rash and were either laboratory-confirmed or had an epidemiological link to a laboratory-confi...
['Adult', 'Arizona', 'Disease Outbreaks', 'Female', 'History, 21st Century', 'Humans', 'Immunoenzyme Techniques', 'Immunoglobulin G', 'Immunoglobulin M', 'Male', 'Measles', 'Middle Aged', 'Polymerase Chain Reaction', 'Prisons', 'Public Health Surveillance', 'Serologic Tests', 'Young Adult']
30,256,908
[['M01.060.116'], ['Z01.107.567.875.760.100'], ['N06.850.290'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['D12.776.124.486.48...
['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]']
0
1
1
1
1
0
0
0
1
1
0
1
1
1
HSP70-hom gene polymorphisms modify the association of diethylhexyl phthalates with insulin resistance.
Recent studies suggest that diethylhexyl phthalates (DEHP) could contribute to the development of insulin resistance (IR) through oxidative stress, and that heat shock protein (HSP) could be related with the association between DEHP and IR. Therefore, we evaluated the effect modification of genetic polymorphisms of HSP...
['Aged', 'Aged, 80 and over', 'Asian Continental Ancestry Group', 'Diethylhexyl Phthalate', 'Environmental Exposure', 'Female', 'HSP70 Heat-Shock Proteins', 'Haplotypes', 'Humans', 'Insulin Resistance', 'Middle Aged', 'Phthalic Acids', 'Polymorphism, Single Nucleotide']
25,044,062
[['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.686.508.200'], ['D02.241.223.805.250'], ['N06.850.460.350'], ['D12.776.580.216.375'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['M01.060.116.630'], ['D02.241.223.805'], ['G05.365.795.598']]
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]']
0
1
1
1
0
0
1
0
0
0
0
1
1
0
Variability of antioxidant and antibacterial effects of essential oils and acetonic extracts of two edible halophytes: Crithmum maritimum L. and Inula crithmo?des L.
This work aimed to assess the richness of the food halophytes Crithmum maritimum and Inula crithmo?des on phenolics and essential oils (EOs) and to evaluate the antioxidant and antibacterial potential of these metabolites. Results displayed that extract of I. crithmo?des possesses considerable contents of phenolic comp...
['Acetone', 'Anti-Bacterial Agents', 'Antioxidants', 'Apiaceae', 'Climate', 'Dietary Supplements', 'Estuaries', 'Ethnopharmacology', 'Gram-Negative Bacteria', 'Gram-Positive Bacteria', 'Inula', 'Iron Chelating Agents', 'Monoterpenes', 'Oils, Volatile', 'Phenols', 'Plant Components, Aerial', 'Plant Extracts', 'Polypheno...
24,128,580
[['D02.522.064'], ['D27.505.954.122.085'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['B01.650.940.800.575.912.250.075'], ['G16.500.275.071', 'N06.230.300.100.250'], ['G07.203.300.456', 'J02.500.456'], ['G01.311.625.540'], ['H01.158.703.015', 'H02.628.100', 'I01.076.201.450.654.252'], ['B03.440'], ...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment ...
1
1
0
1
1
0
1
1
1
1
0
0
1
1
Polycystic kidney disease: prospective analysis of nonazotemic patients and family members.
To develop a profile of nonazotemic polycystic kidney disease as it occurs in families, we identified and studied 164 persons with autosomal-dominant polycystic kidney disease, 81 persons suspected of having the disease, and 250 family members without the disease. Because symptoms were absent in 32% of patients with th...
['Adolescent', 'Adult', 'Blood Chemical Analysis', 'Blood Urea Nitrogen', 'Child', 'Creatinine', 'Cysts', 'Female', 'Headache', 'Hematuria', 'Humans', 'Hypertension, Renal', 'Kidney', 'Kidney Diseases', 'Liver', 'Liver Diseases', 'Male', 'Middle Aged', 'Nausea', 'Physical Examination', 'Polycystic Kidney Diseases', 'Ul...
6,742,648
[['M01.060.057'], ['M01.060.116'], ['E01.370.225.124.100', 'E05.200.124.100'], ['E01.370.225.124.100.115', 'E01.370.390.400.100', 'E05.200.124.100.115'], ['M01.060.406'], ['D03.383.129.308.207'], ['C04.182', 'C23.300.306'], ['C23.888.592.612.441'], ['C12.777.934.442', 'C13.351.968.934.442', 'C23.550.414.849'], ['B01.05...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]']
1
1
1
1
1
0
0
0
0
0
0
1
0
0
Robotic-assisted laparoscopic implantation of artificial urinary sphincter in women with intrinsic sphincter deficiency incontinence: initial results.
OBJECTIVE: To investigate the feasibility, safety, and functional results of robotic-assisted artificial urinary sphincter (R-AUS) laparoscopic implantation in women with stress urinary incontinence due to intrinsic sphincter deficiency.PATIENTS AND METHODS: Six women underwent an R-AUS implantation between 2012 and 20...
['Aged', 'Equipment Design', 'Feasibility Studies', 'Female', 'Humans', 'Laparoscopy', 'Middle Aged', 'Operative Time', 'Perioperative Period', 'Postoperative Complications', 'Prosthesis Implantation', 'Robotic Surgical Procedures', 'Treatment Outcome', 'Urinary Bladder', 'Urinary Incontinence, Stress', 'Urinary Sphinc...
25,443,911
[['M01.060.116.100'], ['E05.320'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['M01.060.116.630'], ['E04.614.374.500', 'N02.421.585.753.374.500'], ['E04.614', 'N02.421.585.753'], ['C23.550...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]']
1
1
1
0
1
0
0
0
0
1
0
1
1
0
Anatomical variations and dimensions of arteries in the anterior part of the circle of Willis.
BACKGROUND: The aim of this study was to investigate different anatomic variations and dimensions of anterior part of the circle of Willis (CW) and their prevalence on Kosovo's population.MATERIALS AND METHODS: This is an observational descriptive and retrospective study performed at the University Clinical Centre, Cli...
['Adult', 'Anatomic Variation', 'Circle of Willis', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Magnetic Resonance Angiography', 'Male', 'Middle Aged']
30,311,936
[['M01.060.116'], ['G07.049', 'G16.117.500'], ['A07.015.114.228.351'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.350.825.500.500', 'E01.370.370.050.500'], ['M01.060.116.630']]
['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]']
1
1
0
0
1
0
1
0
0
0
1
1
0
0
Analysis of the trinucleotide CAG repeat from the DNA polymerase gamma gene (POLG) in patients with Parkinson's disease.
The human gene for the catalytic subunit of the mitochondrial DNA (mtDNA) polymerase (POLG) contains a trinucleotide CAG repeat encoding a polyglutamine tract near the amino-terminus of the protein. Expansions of similar polyglutamine-encoding CAG microsatellite repeats in other genes are known to cause neurodegenerati...
['Adult', 'Aged', 'Aged, 80 and over', 'Alleles', 'DNA Polymerase gamma', 'DNA-Directed DNA Polymerase', 'Female', 'Humans', 'Male', 'Middle Aged', 'Parkinson Disease', 'Peptides', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction', 'Trinucleotide Repeats']
15,694,274
[['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G05.360.340.024.340.030'], ['D08.811.913.696.445.308.300.169', 'D12.776.575.280'], ['D08.811.913.696.445.308.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750'...
['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
1
1
1
0
1
0
0
0
0
1
0
0
Circulating progenitor cells and the elderly: a seven-year observational study.
Cardiovascular (CV) diseases and related complications are the main causes of morbidity and mortality in the elderly. CV progenitor cells, including CD34+ cells, play a role in delaying the progression of atherosclerosis. In the present study we observed 100 octogenarians for seven years, in order to address the questi...
['Aged, 80 and over', 'Aging', 'Antigens, CD34', 'Antioxidants', 'Biomarkers', 'Cardiovascular Diseases', 'Cell Count', 'Female', 'Follow-Up Studies', 'Hematopoietic Stem Cells', 'Humans', 'Longevity', 'Male', 'Prognosis', 'Risk Factors', 'Sicily']
22,449,458
[['M01.060.116.100.080'], ['G07.345.124'], ['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D23.101'], ['C14'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.52...
['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]']
1
1
1
1
1
0
1
0
0
0
0
1
1
1
Chronic disease risk factors in rural Australia: results from the Greater Green Triangle risk factor surveys.
The aim of this article was to assess the level and prevalence of major chronic disease risk factors among rural adults. Two cross-sectional surveys were carried out in 2004 and 2005 in the southeast of South Australia and the southwest of Victoria. Altogether 891 randomly selected persons aged 25 to 74 years participa...
['Adult', 'Aged', 'Cardiovascular Diseases', 'Chronic Disease', 'Cross-Sectional Studies', 'Female', 'Health Behavior', 'Humans', 'Male', 'Middle Aged', 'Obesity', 'Prevalence', 'Risk Factors', 'Rural Health', 'Smoking', 'South Australia', 'Victoria']
19,124,336
[['M01.060.116'], ['M01.060.116.100'], ['C14'], ['C23.550.291.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G0...
['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]']
0
1
1
0
1
1
1
0
0
0
0
1
1
1
Is the secure base phenomenon evident here, there, and anywhere? A cross-cultural study of child behavior and experts' definitions.
The evolutionary rationale offered by Bowlby implies that secure base relationships are common in child-caregiver dyads and thus, child secure behavior observable across diverse social contexts and cultures. This study offers a test of the universality hypothesis. Trained observers in nine countries used the Attachment...
['Adolescent', 'Adult', 'Attitude of Health Personnel', 'Child', 'Child Behavior', 'Child Development', 'Child, Preschool', 'Cross-Cultural Comparison', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mother-Child Relations', 'Object Attachment', 'Observer Variation', 'Pediatrics', 'Young Adult']
23,495,673
[['M01.060.057'], ['M01.060.116'], ['F01.100.050', 'N05.300.100'], ['M01.060.406'], ['F01.145.179'], ['F01.525.200', 'G07.345.374.750'], ['M01.060.406.448'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.829.263.370.290.170'], ['F02.739.794.6...
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]']
0
1
0
0
1
1
1
1
1
0
0
1
1
0
Association studies of the IL-23R gene in autoimmune thyroid disease in the Japanese population.
Autoimmune thyroid diseases (AITDs), including Graves' disease (GD) and Hashimoto's thyroiditis (HT), are caused by interplays of genetic factors and environmental triggers. Interleukin-23 and its receptor (IL-23R) guide T cells towards the Th17 phenotype. IL-23R single nucleotide polymorphisms (SNPs) have been shown t...
['Alleles', 'Asian Continental Ancestry Group', 'Case-Control Studies', 'Female', 'Gene Frequency', 'Genetic Predisposition to Disease', 'Genetics, Population', 'Genotype', 'Graves Disease', 'Graves Ophthalmopathy', 'Hashimoto Disease', 'Humans', 'Interleukin-23', 'Japan', 'Polymorphism, Single Nucleotide', 'Receptors,...
19,021,011
[['G05.360.340.024.340.030'], ['M01.686.508.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G05.330'], ['C23.550.291.687.500', 'G05.380.355'], ['H01.158.273.343.335'], ['G05.380'], ['C11.675.349.500', 'C19.874.283.605', 'C19.874.397.370', 'C20.111.555'], ['C11.270.240', 'C11.675....
['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]']
0
1
1
1
1
0
1
1
0
0
0
1
1
1
Effect of taurine on angiotensin II-induced hypertrophy of neonatal rat cardiac cells.
The effect of taurine on angiotensin II-induced hypertrophy of cultured neonatal rat heart cells (myocytes and nonmyocytes) was examined. Angiotensin II (1-100 nM) alone caused an increase in the rate of protein synthesis of myocytes without changing the rate of DNA synthesis and cell number. It mediated increases in D...
['Angiotensin II', 'Animals', 'Animals, Newborn', 'Genes, Immediate-Early', 'Heart', 'Hyperplasia', 'Hypertrophy', 'Myocardium', 'Rats', 'Rats, Wistar', 'Taurine']
9,436,809
[['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['B01.050'], ['B01.050.050.282'], ['G05.360.340.024.340.330', 'G05.360.340.024.340.364.875.345', 'G05.360.340.358.024.875.345', 'G05.360.340.358.840.500.345'], ['A07.541'], ['...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]']
1
1
1
1
0
0
1
0
0
0
0
0
0
0
Oxidative Stress Mediates the Antiproliferative Effects of Nelfinavir in Breast Cancer Cells.
The discovery of the anti-proliferative activity of nelfinavir in HIV-free models has encouraged its investigation as anticancer drug. Although the molecular mechanism by which nelfinavir exerts antitumor activity is still unknown, its effects have been related to Akt inhibition. Here we tested the effects of nelfinavi...
['Antineoplastic Agents', 'Apoptosis', 'Breast Neoplasms', 'Cell Proliferation', 'Female', 'HIV Protease Inhibitors', 'Humans', 'Nelfinavir', 'Oxidative Stress', 'Reactive Oxygen Species', 'Tumor Cells, Cultured']
27,280,849
[['D27.505.954.248'], ['G04.146.954.035'], ['C04.588.180', 'C17.800.090.500'], ['G04.161.750', 'G07.345.249.410.750'], ['D27.505.519.389.745.900.500', 'D27.505.954.122.388.077.088.420'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.531.520'], ['G03.673', 'G07.775.750'], ['D01.339.431', 'D01.650.775'],...
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]']
1
1
1
1
0
0
1
0
0
0
0
0
0
0
A Cloud Based Potentially Inappropriate Medication Management System Using Patient Owned Personal Health Records.
Taiwan has been confronted with a serious problem of aging in recent years. The prevalence of the chronic diseases caused by aging is increased continuously, which has led to a high percentage of comorbidity and polypharmacy. The proportion of the elderly people with polypharmacy (over three to five kinds of drugs) is ...
['Aged', 'Cloud Computing', 'Health Records, Personal', 'Humans', 'Inappropriate Prescribing', 'Potentially Inappropriate Medication List', 'Risk Factors', 'Taiwan']
29,857,437
[['M01.060.116.100'], ['L01.224.097'], ['E05.318.308.940.968.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.490', 'N02.421.450.500.249'], ['N04.761.700.615', 'N05.700.594'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.8...
['Named Groups [M]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]']
0
1
0
0
1
0
0
0
0
0
1
1
1
1
[Serotypes of Salmonella enterica in sewage effluent from Zaragoza. Comparison with clinical isolates. 1982-1989].
Between 1982 and 1989, 560 Salmonella enterica strains belonging to 63 serovars, were isolated from Zaragoza urban sewage. During the same period of time there were 45 different serovars isolated from faeces of patients from a hospital (in the same city). Only a reduced number of serovars comprised the majority of the ...
['Agglutination Tests', 'Humans', 'Salmonella', 'Salmonella Infections', 'Sewage', 'Spain', 'Water Microbiology']
1,867,775
[['E01.370.225.812.735.050', 'E05.200.812.735.050', 'E05.478.594.760.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.440.450.425.800', 'B03.660.250.150.710'], ['C01.150.252.400.310.821'], ['D20.944.932.500'], ['Z01.542.846'], ['H01.158.273.540.274.777', 'N06.850.425.450']]
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Health Care [N]']
0
1
1
1
1
0
0
1
0
0
0
0
1
1
The relevance of equity in health care for primary care: creating and sustaining a 'fair go, for a fair innings'.
This paper provides an 'equity lens' through which practitioners, policy makers and researchers can measure and monitor the equity of healthcare services provided. An argument is put forward which shows that services need to be assessed in terms of inequities, as opposed to the more often used terms of inequalities or ...
['Australia', 'Health Services Accessibility', 'Health Services Needs and Demand', 'Humans', 'Primary Health Care', 'Social Justice', 'Socioeconomic Factors']
19,281,674
[['Z01.639.100', 'Z01.678.100.373'], ['N04.590.374.350', 'N05.300.430'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.233.727'], ['I01.880.604.473.700', 'K01.752.566.479.830.750', 'N03.706.437.700', 'N05.350.958.750'], ['I01.880.853.996', 'N01.824']]
['Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]']
0
1
0
0
0
0
0
0
1
0
0
0
1
1
The potential for water hyacinth to improve the quality of Bogota River water in the Mu?a Reservoir: comparison with the performance of waste stabilization ponds.
The potential application of Water Hyacinth (Eichhornia crassipes) in organic matter degradation, sedimentation, nutrient and heavy metal absorption and sulfur reduction in the Mu?a Reservoir has been tested in experimental lagoons. The lagoons were operated at hydraulic retention times (HRT) of 6, 9 and 15 days. One l...
['Adsorption', 'Conservation of Natural Resources', 'Ecosystem', 'Eutrophication', 'Geologic Sediments', 'Hydrogen Sulfide', 'Metals, Heavy', 'Organic Chemicals', 'Plants', 'Water Movements', 'Water Purification']
11,833,723
[['G01.030', 'G02.020'], ['J01.256', 'N06.230.080'], ['G16.500.275.157', 'N06.230.124'], ['G16.500.285'], ['G01.311.330', 'G16.500.320'], ['D01.029.260.340', 'D01.362.350', 'D01.875.350'], ['D01.268.556', 'D01.552.544'], ['D02'], ['B01.650'], ['G16.500.971', 'N06.230.132.644.750', 'N06.230.850'], ['N06.850.780.200.800....
['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]']
0
1
0
1
0
0
1
0
0
1
0
0
1
0
Inhibition of DNA methyltransferases in vitro by benzo[a]pyrene diol epoxide-modified substrates.
Covalent adducts formed from the ultimate carcinogen 7 beta,8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[ a]pyrene inhibit the enzyme-catalyzed transfer of methyl groups from S-adenosylmethionine to cytosine residues in DNA. Two DNA methyltransferase enzymes, isolated from the bacterium Haemophilu...
['7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide', 'Animals', 'Base Sequence', 'Benzopyrenes', 'Cattle', 'DNA', 'DNA (Cytosine-5-)-Methyltransferases', 'DNA-Cytosine Methylases', 'Haemophilus', 'Male', 'Methyltransferases', 'Mice', 'Salmon', 'Spleen']
6,430,903
[['D02.455.426.559.847.799.306.400.350', 'D04.615.799.306.400.350'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D02.455.426.559.847.799.306', 'D04.615.799.306'], ['B01.050.150.900.649.313.500.380.271'], ['D13.444.308'], ['D08.811.913.555.500.350.100.500'], ['D08.811.913.555.500.350.100'],...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]']
1
1
0
1
0
0
1
0
0
0
1
0
0
0
Air pollution: the knowledge and ideas of students in Tehran-Iran, and a comparison with other countries.
Study of students' knowledge about air pollution can help authorities to have better imagination of this critical environmental problem. This research examines guidance school and high school students' ideas about air pollution and the results may be useful for the respective authorities to improve cultural and educati...
['Adolescent', 'Air Pollution', 'Child', 'Cognition', 'Cross-Sectional Studies', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Iran', 'Male', 'Students', 'Surveys and Questionnaires']
23,945,895
[['M01.060.057'], ['N06.850.460.100'], ['M01.060.406'], ['F02.463.188'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.350'], ['M01.848'], ['E05.318.308.980', 'N05.715.360.300.800'...
['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]']
0
1
0
0
1
1
0
0
0
0
0
1
1
1
A multicenter, randomized controlled trial of individualized occupational therapy for patients with schizophrenia in Japan.
The individualized occupational therapy (IOT) program is a psychosocial program that we developed to facilitate proactive participation in treatment and improve cognitive functioning and other outcomes for inpatients with acute schizophrenia. The program consists of motivational interviewing, self-monitoring, individua...
['Adult', 'Cognition', 'Humans', 'Male', 'Motivational Interviewing', 'Neuropsychological Tests', 'Occupational Therapy', 'Patient Discharge', 'Patient Education as Topic', 'Schizophrenia']
29,621,261
[['M01.060.116'], ['F02.463.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.784.176.279.500', 'F04.408.413.349.500', 'N02.421.461.363.349.500'], ['F04.711.513'], ['E02.760.169.063.500.489', 'E02.831.489', 'H02.010.500'], ['E02.760.169.125', 'E02.760.400.610', 'N02.421.585.169.125', 'N02.421.585.400.610', ...
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]']
0
1
0
0
1
1
0
1
1
0
0
1
1
0
Long-distance colonization, isolation by distance, and historical demography in a relictual Mexican pinyon pine (Pinus nelsonii Shaw) as revealed by paternally inherited genetic markers (cpSSRs).
Pinus nelsonii is a relictual pinyon pine distributed across a wide altitudinal range in semiarid zones in Mexico near the border between the States of Nuevo Le?n and Tamaulipas. It also occurs in small patches in the State of San Luis Potos?. Pinus nelsonii is classified in the monotypic subsection Nelsoniae, separate...
['Cluster Analysis', 'DNA, Chloroplast', 'Demography', 'Electrophoresis, Polyacrylamide Gel', 'Evolution, Molecular', 'Genetic Variation', 'Geography', 'Haplotypes', 'Mexico', 'Minisatellite Repeats', 'Models, Genetic', 'Phylogeny', 'Pinus']
12,859,631
[['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['D13.444.308.283.170', 'D13.444.308.435.275'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['E05.196.401.402', 'E05.301.300.319'], ['G05.045.250', 'G16.075.250'], ['G05.365'], ['H01.277.500'], ['G05.380.360'], ['Z01.107.567.589'], ['G02.111.570.080.708...
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Information Science [L]', 'Organisms [B]']
0
1
0
1
1
0
1
1
1
0
1
0
1
1
Pharmacological characterization of histamine receptors in the mouse seminal vesicle: sensitivity to H1- and H2-receptor agonists and antagonists.
Neither histamine nor the more specific H1- or H2-receptor agonists (0.2-220 micrometers) produced a contraction of the mouse seminal vesicle. However, all these agonists decreased resting tone and caused a dose-related inhibition of the electrically evoked twitch responses in these concentrations. The slopes of the pe...
['Animals', 'Cimetidine', 'Dose-Response Relationship, Drug', 'Electric Stimulation', 'Histamine', 'Histamine H1 Antagonists', 'Male', 'Mice', 'Mice, Inbred Strains', 'Muscle Contraction', 'Norepinephrine', 'Receptors, Histamine', 'Seminal Vesicles']
6,121,472
[['B01.050'], ['D02.078.370.200', 'D03.383.129.308.130'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.723.402'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['D27.505.519.625.375.425.400', 'D27.505.696.577.375.425.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050....
['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Web-based asthma collaboration management and public awareness.
Recent studies have shown that long-term monitoring of asthma severity can reduce asthma exacerbations, optimise drug therapy and decrease the cost of asthma management. The management of a chronic patient is a collective and cooperative enterprise that may exploit Information Technologies (IT) to improve the overall q...
['Asthma', 'Disease Management', 'Health Promotion', 'Humans', 'Internet', 'Patient Education as Topic', 'Patient Satisfaction', 'Telemedicine']
15,747,901
[['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['N04.590.607'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['I02.233.332.500', 'N02.421.726.407.680'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', ...
['Diseases [C]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]']
0
1
1
0
0
1
0
1
1
0
1
0
1
0
Evaluation of costs associated with tolvaptan-mediated hospital length of stay reduction among US patients with the syndrome of inappropriate antidiuretic hormone secretion, based on SALT-1 and SALT-2 trials.
BACKGROUND: Two randomized clinical trials, the Study of Ascending Levels of Tolvaptan in Hyponatremia 1 and 2 (SALT-1 and SALT-2), showed that tolvaptan was an efficacious and safe therapy for the treatment of hyponatremic patients with the syndrome of inappropriate antidiuretic hormone secretion (SIADH).HYPOTHESIS: T...
['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Benzazepines', 'Cost Savings', 'Female', 'Health Care Costs', 'Hospitalization', 'Humans', 'Hyponatremia', 'Inappropriate ADH Syndrome', 'Length of Stay', 'Male', 'Middle Aged', 'Monte Carlo Method', 'Randomized Controlled Trials as Topic', 'Tolvaptan...
22,406,878
[['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D03.633.100.079'], ['N03.219.151.160.200'], ['N03.219.151.400', 'N05.300.375'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.950.620'], ['C10.228.1...
['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]', 'Geographicals [Z]']
0
1
1
1
1
0
0
0
0
0
1
1
1
1
[Programmed electrical stimulation in the treatment of reciprocating arrhythmias. Use of radiofrequency as a stimulating and synchronising means (author's transl)].
A new model of radiofrequency stimulator is presented, which can be programmed for the transmission of one or two impulses synchronised and delayed on the endocardial electrogram. This pacemaker was successfully used in jounctional reciprocating tachycardias and in a case of recurrent ventricular tachycardia. The impla...
['Cardiac Pacing, Artificial', 'Humans', 'Pacemaker, Artificial', 'Radio', 'Tachycardia']
754,957
[['E02.331.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.305.250.750'], ['J01.897.280.500.739', 'L01.178.590.700', 'L01.178.820.090.739', 'L01.178.847.514'], ['C14.280.067.845', 'C14.280.123.875', 'C23.550.073.845']]
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Diseases [C]']
0
1
1
0
1
0
0
0
0
1
1
0
0
0
The nontoxic natural compound Curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against malignant gliomas.
BACKGROUND: New drugs are constantly sought after to improve the survival of patients with malignant gliomas. The ideal substance would selectively target tumor cells without eliciting toxic side effects. Here, we report on the anti-proliferative, anti-migratory, and anti-invasive properties of the natural, nontoxic co...
['Antineoplastic Agents', 'Blotting, Western', 'Caspases', 'Cell Adhesion', 'Cell Cycle', 'Cell Movement', 'Cell Proliferation', 'Curcumin', 'Enzyme-Linked Immunosorbent Assay', 'Glioma', 'Humans', 'Neoplasm Invasiveness', 'Phosphorylation', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction', 'STAT3 Tr...
20,840,775
[['D27.505.954.248'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['G04.022'], ['G04.144'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249....
['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]']
1
1
1
1
1
0
1
0
0
0
0
0
0
0
Bone marrow transplantation attenuates the myopathic phenotype of a muscular mouse model of spinal muscular atrophy.
Bone marrow (BM) transplantation was performed on a muscular mouse model of spinal muscular atrophy that had been created by mutating the survival of motor neuron gene (Smn) in myofibers only. This model is characterized by a severe myopathy and progressive loss of muscle fibers leading to paralysis. Transplantation of...
['Animals', 'Antigens, CD34', 'Bone Marrow Cells', 'Bone Marrow Transplantation', 'Cell Proliferation', 'Gene Expression Regulation', 'Green Fluorescent Proteins', 'Hepatocyte Growth Factor', 'Mice', 'Mice, Mutant Strains', 'Muscle Fibers, Skeletal', 'Muscle, Skeletal', 'Muscular Atrophy, Spinal', 'Muscular Diseases', ...
16,888,281
[['B01.050'], ['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['A11.148', 'A15.378.316'], ['E02.095.147.725.040', 'E04.936.580.040'], ['G04.161.750', 'G07.345.249.410.750'], ['G05.308'], ['D12.776.532.265'], ['D12.644.276.374.420', 'D12.776.467.374.420', 'D23.529.374.420'], ['B01.050.150.900.649.313.992.635.505.500...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]']
1
1
1
1
1
0
1
0
0
0
0
0
0
0
The use of copper and silver in carbon point-of-use filters for the suppression of Legionella throughput in domestic water systems.
AIMS: To evaluate throughput of seeded Legionella pneumophila bacteria in domestic point-of-use filters.METHODS AND RESULTS: The filters were challenged with tap water seeded with Leg. pneumophila. After multiple challenge events (4.25 x 10(11) CFU per filter), the levels of Legionella were lower in the effluent from t...
['Biofilms', 'Carbon', 'Copper', 'Disinfection', 'Filtration', 'Fresh Water', 'Household Articles', 'Ions', 'Legionella', 'Silver', 'Temperature', 'Toxicity Tests', 'Water Microbiology', 'Water Purification']
18,042,187
[['A20.593', 'G06.120'], ['D01.268.150'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['N06.850.780.200.450.850.375'], ['E05.196.454', 'G01.280', 'G02.263'], ['G16.500.275.280', 'N06.230.232'], ['J01.494'], ['D01.248.497'], ['B03.440.400.425.450.450', 'B03.660.250.460.460'], ['D01.268.556.812', 'D01.268....
['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Disciplines and Occupations [H]']
1
1
0
1
1
0
1
1
0
1
0
0
1
0
Psychometric properties of the Norwegian version of the patient generated index in patients with rheumatic diseases participating in rehabilitation or self-management programmes.
OBJECTIVE: In rehabilitation, treatment is individually tailored to each patient's goals. Individualized instruments allow patients to choose domains that they consider important, which may make them particularly appropriate as evaluative tools in this setting. We aimed to evaluate the psychometric properties of the No...
['Adolescent', 'Adult', 'Aged', 'Cohort Studies', 'Female', 'Humans', 'Inpatients', 'Male', 'Middle Aged', 'Norway', 'Outcome Assessment, Health Care', 'Pain Measurement', 'Patient Participation', 'Psychometrics', 'Range of Motion, Articular', 'Rehabilitation Centers', 'Reproducibility of Results', 'Rheumatic Diseases'...
23,335,634
[['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['M01.060.116.630'], ['Z01.542.816.374'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['E01.370....
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenome...
0
1
1
0
1
1
1
1
1
0
0
1
1
1
Evaluation of insulin-like growth factor-1, total thyroxine, feline pancreas-specific lipase and urinary corticoid-to-creatinine ratio in cats with diabetes mellitus in Switzerland and the Netherlands.
Objectives The aim of the study was to evaluate circulating insulin-like growth factor-1 (IGF-1), feline pancreas-specific lipase (fPLI) and total thyroxine (TT4) concentrations and urinary corticoid-to-creatinine ratio (UCCR) as indicators for the prevalence of acromegaly, pancreatitis, hyperthyroidism and hypercortis...
['Acromegaly', 'Adrenal Cortex Hormones', 'Animals', 'Cat Diseases', 'Cats', 'Creatinine', 'Cushing Syndrome', 'Diabetes Mellitus', 'Female', 'Hyperthyroidism', 'Insulin-Like Growth Factor I', 'Lipase', 'Male', 'Netherlands', 'Pancreatitis', 'Prevalence', 'Switzerland', 'Thyroxine']
27,578,200
[['C05.116.132.082', 'C10.228.140.617.738.250.100', 'C19.700.355.179'], ['D06.472.040'], ['B01.050'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D03.383.129.308.207'], ['C19.053.800.367'], ['C18.452.394.750', 'C19.246'], ['C19.874.397'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.9...
['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
0
1
1
1
1
0
0
0
0
0
0
0
1
1
Nitric oxide synthase neurons in the rodent spinal cord: distribution, relation to Substance P fibers, and effects of dorsal rhizotomy.
The indirect immunofluorescent method was employed to investigate the distribution of neuronal nitric oxide synthase-like immunoreactivity(nNOS-LI) in the spinal cord of the golden hamster and to compare it to data obtained from rats. Immunoreactive neurons were found throughout the cervico-sacral extent in the dorsal ...
['Animals', 'Autonomic Fibers, Preganglionic', 'Cricetinae', 'Immunohistochemistry', 'Male', 'Mesocricetus', 'Nerve Fibers', 'Neurons', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type I', 'Perfusion', 'Rats', 'Rats, Sprague-Dawley', 'Rhizotomy', 'Spinal Cord', 'Substance P']
11,312,059
[['B01.050'], ['A08.675.127.500.060', 'A08.675.542.234.060', 'A08.800.050.050.060', 'A08.800.800.060.060', 'A11.671.188.500.060', 'A11.671.501.234.060'], ['B01.050.150.900.649.313.992.635.075.250'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01....
['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]']
1
1
0
1
1
0
0
1
0
0
0
0
0
0
Myocardial expression of the endothelin system in endotoxin-treated rats.
Although circulating plasma levels of endothelin (ET)-1 are elevated in endotoxemia, little is known about the myocardial expression of the ET system in endotoxic shock. We assessed the temporal mRNA expression pattern of key components of the ET system (pre-pro ET (ppET) -1, -2, ET-converting enzyme-1, ET(A) and ET(B)...
['Animals', 'Aspartic Acid Endopeptidases', 'Endothelin-1', 'Endothelin-Converting Enzymes', 'Endothelins', 'Endotoxins', 'Injections, Intraperitoneal', 'Lipopolysaccharides', 'Male', 'Metalloendopeptidases', 'Myocardium', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type II', 'Protein Precursors', 'RNA, Messenger',...
11,483,876
[['B01.050'], ['D08.811.277.656.074.500', 'D08.811.277.656.300.048'], ['D12.644.276.400.225', 'D12.776.467.400.225', 'D23.529.400.225'], ['D08.811.277.656.074.500.270', 'D08.811.277.656.300.048.270', 'D08.811.277.656.300.480.229', 'D08.811.277.656.675.374.229'], ['D12.644.276.400', 'D12.776.467.400', 'D23.529.400'], ['...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]']
1
1
0
1
1
0
0
0
0
0
0
0
0
0
Relation of serum insulin-like growth factor-I (IGF-I) and IGF binding protein-3 to risk of prostate cancer (United States).
OBJECTIVE: Insulin-like growth factor I (IGF-I) exerts potent mitogenic and antiapoptotic effects on prostatic epithelial cells. Insulin-like growth factor binding protein-3 (IGFBP-3) modulates the effects of IGF-I, and independently induces apoptosis and inhibits cell growth. Previous studies have inconsistently assoc...
['Aged', 'Case-Control Studies', 'Humans', 'Insulin-Like Growth Factor Binding Protein 3', 'Insulin-Like Growth Factor I', 'Logistic Models', 'Male', 'Middle Aged', 'Prostatic Neoplasms', 'Risk Factors', 'United States']
14,674,736
[['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.420.270'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]']
0
1
1
1
1
0
0
0
0
0
0
1
1
1
Oral administration of misoprostol for labor induction: a randomized controlled trial.
OBJECTIVE: To evaluate the effectiveness, safety, and gastrointestinal tolerance of misoprostol taken orally for induction of labor, against our established protocol, with the interval from induction to vaginal birth as the primary outcome measure.METHODS: Two hundred seventy-five women who presented with indication fo...
['Administration, Oral', 'Adult', 'Confidence Intervals', 'Female', 'Follow-Up Studies', 'Humans', 'Labor, Induced', 'Misoprostol', 'Oxytocics', 'Pregnancy', 'Time Factors']
9,052,592
[['E02.319.267.100'], ['M01.060.116'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.520.252.968'], ['D10.251.355.255.550.775.450.500', 'D23.469.050.175....
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]']
0
1
0
1
1
0
1
0
0
0
0
1
1
0
Opening of potassium channels protects mitochondrial function from calcium overload.
Ischemic preconditioning (IPC) protects myocardium from ischemia reperfusion injury by activating mitochondrial K(ATP) channels. However, the mechanism underlying the protective effect of K(ATP) channel activation has not been elucidated. It has been suggested that activation of mitochondrial K(ATP) channels may preven...
['Animals', 'Calcium', 'Ion Channel Gating', 'Ischemic Preconditioning', 'Kinetics', 'Male', 'Mitochondria, Heart', 'Oxidative Phosphorylation', 'Oxygen Consumption', 'Pinacidil', 'Polarography', 'Potassium Channels', 'Rats', 'Rats, Sprague-Dawley']
11,104,651
[['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.400', 'G04.835.400', 'G07.265.625'], ['E02.592', 'E05.516'], ['G01.374.661', 'G02.111.490'], ['A11.284.430.214.190.875.564.627.603', 'A11.284.835.626.627.603'], ['G02.111.665.550', 'G03.295.631', 'G03.796.550'], ['G03.680'], ['D02.078.37...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Effects of cardiac rehabilitation and exercise training on low-density lipoprotein cholesterol in patients with hypertriglyceridemia and coronary artery disease.
Substantial data suggest that elevated triglycerides are associated with increased coronary risk, and may be an independent coronary risk factor. Although it is generally accepted that patients with hypertriglyceridemia can have marked improvement in lipids after vigorous nonpharmacologic therapy, data to support this ...
['Adult', 'Aged', 'Aged, 80 and over', 'Cholesterol', 'Cholesterol, LDL', 'Coronary Disease', 'Exercise Therapy', 'Female', 'Humans', 'Hypertriglyceridemia', 'Male', 'Middle Aged', 'Treatment Outcome', 'Triglycerides']
7,977,088
[['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.244', 'D10.532.515.500', 'D10.570.938.208.275', 'D12.776.521.550.500'], ['C14.280.647.250', 'C14.907.585.250'], ['E02.760.169.063.500.387', 'E02.779.483', ...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]']
0
1
1
1
1
0
0
0
0
0
0
1
1
0
Concurrent progressive-ratio schedules to compare reinforcing effectiveness of different phencyclidine (PCP) concentrations in rhesus monkeys.
RATIONALE: Progressive ratio (PR) schedules have become well accepted for testing the reinforcing effectiveness of drugs. This study extends the methods to concurrent PR schedules with different concentrations of orally delivered phencyclidine (PCP).OBJECTIVE: The sensitivity of the procedure is tested by presenting di...
['Administration, Oral', 'Animals', 'Behavior, Animal', 'Hallucinogens', 'Macaca mulatta', 'Male', 'Phencyclidine', 'Reinforcement Schedule']
10,394,998
[['E02.319.267.100'], ['B01.050'], ['F01.145.113'], ['D27.505.696.388', 'D27.505.954.427.700.372'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['D03.383.621.699'], ['F02.463.425.770.644']]
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]']
0
1
0
1
1
1
0
0
0
0
0
0
0
0
Electrophysiological studies of the visual system in myotonic dystrophy.
Ocular signs and electroretinal alterations frequently occur in Myotonic Dystrophy (MD). Surprisingly few reports describe VEP abnormalities for this syndrome. Since the evaluation of cortical visual responses is linked to an understanding of preceding retinal changes, we conducted a systematic study of the visual syst...
['Adult', 'Aged', 'Dark Adaptation', 'Electrooculography', 'Electroretinography', 'Evoked Potentials, Visual', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myotonic Dystrophy', 'Reaction Time', 'Retina', 'Visual Cortex', 'Visual Pathways']
3,425,222
[['M01.060.116'], ['M01.060.116.100'], ['G14.020.371'], ['E01.370.380.230.285', 'E01.370.405.245.787.285'], ['E01.370.380.225', 'E01.370.405.270'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.651.534.500.500', 'C05.651.662.750', ...
['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]']
1
1
1
0
1
1
1
0
0
0
0
1
0
0
Detection of Redox State Evolution during Wound Healing Process Based on a Redox-Sensitive Wound Dressing.
To detect the redox state evolution during wound healing process, a redox-sensitive surface-enhanced Raman scattering (SERS) probe was constructed by attaching anthraquinone as a redox-sensitive molecule onto gold nanoshells, and the redox-sensitive SERS probes were loaded on one surface of a chitosan membrane as a red...
['Animals', 'Anthraquinones', 'Chitosan', 'Gold', 'Male', 'Metal Nanoparticles', 'Mice', 'Mice, Inbred ICR', 'Molecular Probes', 'Molecular Structure', 'Oxidation-Reduction', 'Particle Size', 'Spectrum Analysis, Raman', 'Surface Properties', 'Wound Healing']
29,757,626
[['B01.050'], ['D02.455.426.559.847.117.159', 'D02.806.100', 'D04.615.117.159'], ['D05.750.078.139.500', 'D09.698.211.500'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['J01.637.512.600.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.510', 'B01.050.150.900.649.313.992.635.5...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
0
1
1
0
1
0
0
1
0
0
0
0
Metal substitution in transferrins: specific binding of cerium(IV) revealed by the crystal structure of cerium-substituted human lactoferrin.
Proteins of the transferrin family play a key role in iron homeostasis through their extremely strong binding of iron, as Fe3+. They are nevertheless able to bind a surprisingly wide variety of other metal ions. To investigate how metal ions of different size, charge and coordination characteristics are accommodated, w...
['Cerium', 'Crystallography, X-Ray', 'Humans', 'Lactoferrin', 'Models, Molecular', 'Protein Binding', 'Protein Conformation', 'Transferrin']
11,128,996
[['D01.268.558.362.249', 'D01.552.550.399.249'], ['E05.196.309.742.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.277.656.300.760.471', 'D08.811.277.656.959.350.471', 'D12.776.157.427.750.249', 'D12.776.256.159.750.816.500.507', 'D12.776.377.457.507', 'D12.776.395.507', 'D12.776.556.579.750.249'], ['...
['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]']
0
1
0
1
1
0
1
0
0
0
0
0
0
0
Stimulatory effects of vasoactive intestinal peptide and pituitary adenylate cyclase-activating peptide on tuberoinfundibular dopaminergic neuron activity in estrogen-treated ovariectomized rats and their correlation with prolactin secretion.
The effects of central administration of vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating peptide (PACAP) on hypothalamic tuberoinfundibular dopaminergic neuron activity and serum prolactin (PRL) levels were reported. Adult female Sprague-Dawley rats overiectomized for 2 weeks, implanted w...
['Animals', 'Dopamine', 'Estrogen Replacement Therapy', 'Female', 'Injections, Intraventricular', 'Median Eminence', 'Neurons', 'Neuropeptides', 'Ovariectomy', 'Ovary', 'Pituitary Adenylate Cyclase-Activating Polypeptide', 'Prolactin', 'Rats', 'Rats, Sprague-Dawley', 'Stimulation, Chemical', 'Vasoactive Intestinal Pept...
8,875,438
[['B01.050'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['E02.319.452.150'], ['E02.319.267.530.550'], ['A06.688.178.750', 'A06.688.357.500', 'A08.186.211.180.497.352.435.249', 'A08.186.211.200.317.357.352.435.249', 'A08.713.049.750', 'A08.713.357.500'], ['A08.675', 'A11.671'], [...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Role of Bcl-2, Bax, and Bak in spontaneous apoptosis and proliferation in neuroendocrine lung tumors: immunohistochemical study.
Fifty-six primary neuroendocrine lung tumors were examined morphologically and histologically and their apoptosis level was determined. Malignant carcinomas were characterized by increased apoptotic index and enhanced expression ofBcl-2, Bak, p53, and Ki-67 compared to typical carcinoid. However, apoptosis in these tum...
['Apoptosis', 'Carcinoid Tumor', 'Carcinoma, Small Cell', 'Cell Division', 'Female', 'Humans', 'Immunohistochemistry', 'Lung Neoplasms', 'Male', 'Membrane Proteins', 'Middle Aged', 'Neuroendocrine Tumors', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-bcl-2', 'bcl-2 Homologous Antagonist-Killer Protein', 'bcl-2...
11,140,590
[['G04.146.954.035'], ['C04.557.465.625.650.200', 'C04.557.470.200.025.200', 'C04.557.580.625.650.200'], ['C04.557.470.200.380'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500...
['Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Named Groups [M]']
0
1
1
1
1
0
1
1
0
0
0
1
0
0
Spontaneous generation of reactive oxygen species in the mixture of cyanide and glycerol.
Reactive oxygen species are involved in tumor promotion or apoptosis. In assaying prooxidant or antioxidant activities, cyanide has been commonly used as an inhibitor of mitochondrial oxidases, peroxidases, or Cu,Zn-superoxide dismutase, which have an influence on intracellular levels of reactive oxygen species. It has...
['Cyanides', 'Cytochromes c', 'Electron Spin Resonance Spectroscopy', 'Erythrocytes', 'Glycerol', 'Humans', 'In Vitro Techniques', 'Lipid Peroxidation', 'Nitroblue Tetrazolium', 'Paraquat', 'Reactive Oxygen Species', 'Vitamin K 3']
15,659,779
[['D01.248.497.158.291', 'D01.625.400.100'], ['D08.244.286.100', 'D12.776.422.220.286.100'], ['E05.196.867.519.274'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D02.033.800.875.500', 'D09.853.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['G02.111.515', 'G03.295.531.587'], ['D03.383...
['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
[Relationship between heparanase mRNA expression in human gastric cancer and its clinicopathological features].
OBJECTIVE: To explore the relationship between heparanase mRNA expression and clinicopathological parameters in human gastric cancer.METHODS: RT-PCR was used to detect the expression of heparanase mRNA in 43 human gastric carcinomas and 10 adjacent normal gastric tissues.RESULTS: Heparanase mRNA was expressed in 29 of ...
['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Glucuronidase', 'Humans', 'Liver Neoplasms', 'Lymph Nodes', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Staging', 'RNA, Messenger', 'Stomach Neoplasms']
15,634,522
[['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.811.277.450.426'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['A10.549.400', 'A15.382.520.604.412'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], [...
['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
1
1
1
0
0
0
0
0
0
1
0
0
Microbial agents associated with pneumonia in children from Uruguay.
The etiology of severe pneumonia, not frequently encountered in a community-based study, was determined in 204 hospitalized children less than 5 years of age. Potential pathogens were identified in 41% of episodes. Viruses were isolated or antigen was detected in 36.3% of cases; 82.4% of these cases were due to respira...
['Age Factors', 'Bacterial Infections', 'Child, Preschool', 'Humans', 'Infant', 'Pharynx', 'Pleural Effusion', 'Pneumonia', 'Pneumonia, Viral', 'Prevalence', 'Seasons', 'Sepsis', 'Uruguay']
2,270,414
[['N05.715.350.075', 'N06.850.490.250'], ['C01.150.252'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A03.556.750', 'A04.623', 'A14.724'], ['C08.528.652'], ['C01.748.610', 'C08.381.677', 'C08.730.610'], ['C01.748.610.763', 'C01.925.705', 'C08.381.677.807', 'C08.730.610.763']...
['Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]']
1
1
1
0
1
0
1
0
0
0
0
1
1
1
Synergistic effects of FGF-2 with insulin or IGF-I on the proliferation of human auricular chondrocytes.
Chondrocyte preparation with the safety and efficiency is the first step in cartilage regenerative medicine. To prepare a chondrocyte proliferation medium that does not contain fetal bovine serum (FBS) and that provides more than a 1000-fold increase in cell numbers within approximately 1 month, we attempted to use the...
['Adolescent', 'Analysis of Variance', 'Cell Proliferation', 'Cells, Cultured', 'Child', 'Chondrocytes', 'Culture Media', 'Drug Synergism', 'Fibroblast Growth Factor 2', 'Humans', 'Insulin', 'Insulin-Like Growth Factor I', 'Tissue Engineering']
16,405,079
[['M01.060.057'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['M01.060.406'], ['A11.329.171'], ['D27.720.470.305', 'E07.206'], ['G07.690.773.968.477'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['B01.050.150.900.649.31...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]']
1
1
0
1
1
0
1
0
0
1
0
1
1
0
Effects of incomplete pulmonary gas exchange on VO2 max.
Recent evidence suggests that heavy exercise may lower the percentage of O2 bound to hemoglobin (%SaO2) by greater than or equal to 5% below resting values in some highly trained endurance athletes. We tested the hypothesis that pulmonary gas exchange limitations may restrict VO2max in highly trained athletes who exhib...
['Adult', 'Exercise', 'Humans', 'Hypoxia', 'Male', 'Oxygen Consumption', 'Physical Fitness', 'Pulmonary Gas Exchange']
2,745,310
[['M01.060.116'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.079'], ['G03.680'], ['G11.427.685', 'I03.450.642.845.054.800', 'N01.400.545'], ['E01.370.386.700.650', 'G03.143.775.602', 'G09.772.705.760.602']]
['Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
1
0
1
0
1
0
1
0
0
1
1
0
[Big Data Revolution or Data Hubris? : On the Data Positivism of Molecular Biology].
Genome data, the core of the 2008 proclaimed big data revolution in biology, are automatically generated and analyzed. The transition from the manual laboratory practice of electrophoresis sequencing to automated DNA-sequencing machines and software-based analysis programs was completed between 1982 and 1992. This tran...
['Algorithms', 'Big Data', 'Data Science', 'History, 20th Century', 'History, 21st Century', 'Human Genome Project', 'Humans', 'Molecular Biology', 'Sequence Analysis, DNA']
29,058,018
[['G17.035', 'L01.224.050'], ['L01.313.500.750.300.092'], ['L01.305'], ['K01.400.504.968'], ['K01.400.504.984'], ['H01.158.273.180.350.174', 'H01.158.273.343.249.400', 'H01.158.273.343.350.174', 'H01.158.273.343.385.875', 'H01.770.644.145.350.500', 'L01.453.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01....
['Phenomena and Processes [G]', 'Information Science [L]', 'Humanities [K]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
0
0
1
0
1
1
0
0
1
0
0
0
[Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD)].
Dementia has become a priority worldwide in terms of both public health and social care due to its rapidly increasing burden in communities. Therefore, the early identification of possible risk factors and the establishment of preventive and treatment strategies for dementia have become increasingly important. The Japa...
['Aged', 'Aged, 80 and over', 'Databases, Factual', 'Dementia', 'Humans', 'Japan', 'Patient Care Team', 'Prospective Studies', 'Research Design', 'Risk Factors']
28,739,990
[['M01.060.116.100'], ['M01.060.116.100.080'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['C10.228.140.380', 'F03.615.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['N04.590.715'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750...
['Named Groups [M]', 'Information Science [L]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]']
0
1
1
0
1
1
0
1
0
0
1
1
1
1
Floral and vegetative cues in oil-secreting and non-oil-secreting Lysimachia species.
BACKGROUND AND AIMS: Unrelated plants pollinated by the same group or guild of animals typically evolve similar floral cues due to pollinator-mediated selection. Related plant species, however, may possess similar cues either as a result of pollinator-mediated selection or as a result of sharing a common ancestor that ...
['Color', 'Flowers', 'Gas Chromatography-Mass Spectrometry', 'Odorants', 'Phylogeny', 'Plant Oils', 'Primulaceae']
22,634,256
[['G01.590.540.199'], ['A18.024.249.500'], ['E05.196.181.349.500', 'E05.196.566.500'], ['G16.500.275.640', 'N06.230.480'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D10.627.700', 'D20.215.784.750'], ['B01.650.940.800.575.912.250.341.984']]
['Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]']
1
1
0
1
1
0
1
0
0
0
1
0
1
0
[Changes in autopsies in cancer in Navarra from 1980 to 1988].
BACKGROUND: Autopsies may be used to know the causes of death in population. In Navarra, the number of patients who died by cancer and were autopsied has increased. A similar pattern appeared in other communities.METHODS: We reviewed 2,643 autopsies performed in the main hospitals of Navarra. In each autopsy, age, sex,...
['Age Factors', 'Aged', 'Autopsy', 'Biliary Tract Neoplasms', 'Colonic Neoplasms', 'Female', 'Humans', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Neoplasms', 'Spain']
2,051,790
[['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['C04.588.274.120', 'C06.130.320', 'C06.301.120'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['B01.050.150.9...
['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]']
0
1
1
0
1
0
0
0
1
0
0
1
1
1
Exploring patient-physician communication in breast cancer care for African American women following primary treatment.
PURPOSE/OBJECTIVES: To investigate patient-physician communication from the patient's perspective about guidelines and sources of information used in developing survivorship care and preferred avenues for information delivery to African American breast cancer survivors.DESIGN: Qualitative.SETTING: Medical centers in th...
['African Americans', 'Breast Neoplasms', 'Communication', 'Female', 'Humans', 'Information Dissemination', 'Middle Aged', 'Physician-Patient Relations', 'Surveys and Questionnaires', 'Survivors']
18,765,331
[['M01.686.508.100.100', 'M01.686.754.100'], ['C04.588.180', 'C17.800.090.500'], ['F01.145.209', 'L01.143'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.143.443'], ['M01.060.116.630'], ['F01.829.401.650.675', 'N05.300.660.625'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['M01.860']]
['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
1
0
1
1
0
0
0
0
1
1
1
0
Renal trauma: kidney preservation through improved vascular control-a refined approach.
Indications for renal exploration, nephrectomy, or renal repair for patients with renal trauma continue to be a subject of controversy. The present survey evaluates the results of two series of patients from a single hospital having had renal exploration for injury: Series I (1964-1973) 185 patients previously reported...
['Adult', 'Female', 'Hematoma', 'Hematuria', 'Humans', 'Kidney', 'Kidney Diseases', 'Methods', 'Nephrectomy', 'Wounds, Gunshot', 'Wounds, Nonpenetrating', 'Wounds, Penetrating']
7,077,686
[['M01.060.116'], ['C23.550.414.838'], ['C12.777.934.442', 'C13.351.968.934.442', 'C23.550.414.849'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['C12.777.419', 'C13.351.968.419'], ['E05.581'], ['E04.950.774.435'], ['C26.986.900'], ['C26.974'], ['C26.986']]
['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
1
0
1
0
0
0
0
0
0
1
0
0
Lumbar spinal stenosis: conservative or surgical management?: A prospective 10-year study.
STUDY DESIGN: A cohort of 100 patients with symptomatic lumbar spinal stenosis, characterized in a previous article, were given surgical or conservative treatment and followed for 10 years.OBJECTIVES: To identify the short- and long-term results after surgical and conservative treatment, and to determine whether clinic...
['Activities of Daily Living', 'Adolescent', 'Adult', 'Aged', 'Back Pain', 'Decision Trees', 'Decompression, Surgical', 'Female', 'Follow-Up Studies', 'Humans', 'Intermittent Claudication', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Neurologic Examination', 'Orthotic Devices', 'Patient Dropouts', 'Prognosis', 'Prospec...
10,828,926
[['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C23.888.592.612.107'], ['G17.162.500'], ['E04.188'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.40...
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]']
1
1
1
0
1
1
1
0
1
0
0
1
1
0
Wave-induced fluid flow in random porous media: attenuation and dispersion of elastic waves.
A detailed analysis of the relationship between elastic waves in inhomogeneous, porous media and the effect of wave-induced fluid flow is presented. Based on the results of the poroelastic first-order statistical smoothing approximation applied to Biot's equations of poroelasticity, a model for elastic wave attenuation...
['Elasticity', 'Models, Theoretical', 'Porosity', 'Temperature']
15,957,744
[['G01.374.590'], ['E05.599'], ['G01.374.710'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']]
['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
0
0
0
0
1
0
1
0
0
0
0
0
1
0
Estimating RNA Polymerase Protein Binding Sites on ë DNA Using Solid-State Nanopores.
In this work, using a silicon nitride nanopore based device, we measure the binding locations of RNA Polymerase (RNAP) on 48.5 kbp (16.5 ìm) long ë DNA. To prevent the separation of bound RNAPs from a ë DNA molecule in the high electric field inside a nanopore, we cross-linked RNAP proteins to ë DNA by formaldehyde. We...
['Binding Sites', 'DNA', 'DNA-Directed RNA Polymerases', 'Formaldehyde', 'Nanopores', 'Protein Binding']
30,561,195
[['G02.111.570.120'], ['D13.444.308'], ['D08.811.913.696.445.735.270'], ['D02.047.407'], ['J01.637.512.650'], ['G02.111.679', 'G03.808']]
['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]']
0
0
0
1
0
0
1
0
0
1
0
0
0
0
Transconjunctival Nd:YAG laser revision of failing trabeculectomy.
We used a Q-switched Nd:YAG laser delivered transconjunctivally to restore filtration to a failing trabeculectomy of a 51-year-old black woman with primary open-angle glaucoma and uncontrolled intraocular pressure (IOP) on maximally tolerated anti-glaucoma medical therapy. Initially, the Nd:YAG laser was directed via a...
['Conjunctiva', 'Female', 'Follow-Up Studies', 'Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Laser Therapy', 'Middle Aged', 'Reoperation', 'Surgical Flaps', 'Trabeculectomy']
2,381,662
[['A09.371.060.200', 'A09.371.337.168'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['E02.594', 'E04.014.520'], ['M01.060.116.630'], ['E04.690'], ['A10.850.710', 'E07.862.710'], ['E04.540.4...
['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]']
1
1
1
0
1
0
1
0
0
0
0
1
1
0
Human SP-A genetic variants and bleomycin-induced cytokine production by THP-1 cells: effect of ozone-induced SP-A oxidation.
Surfactant protein A (SP-A) plays a role in innate host defense. Human SP-A is encoded by two functional genes (SP-A1 and SP-A2), and several alleles have been characterized for each gene. We assessed the effect of in vitro expressed human SP-A genetic variants, on TNF-alpha and IL-8 production by THP-1 cells in the pr...
['Animals', 'Antimetabolites, Antineoplastic', 'Biological Products', 'Bleomycin', 'Cell Line', 'Electrophoresis', 'Humans', 'In Vitro Techniques', 'Insecta', 'Interleukin-8', 'Mutagenesis', 'Oxidants, Photochemical', 'Oxidation-Reduction', 'Ozone', 'Pulmonary Surfactant-Associated Protein A', 'Tumor Necrosis Factor-al...
14,617,519
[['B01.050'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['D20.215'], ['D09.400.420.110', 'D12.644.233.110'], ['A11.251.210'], ['E05.196.401', 'E05.301.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['B01.050.500.131.617'], ['D12.644.276.374.200.120.800', 'D12.644.276.3...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Augmented gentamicin ototoxicity induced by vancomycin in guinea pigs.
Vancomycin has been reported to be an ototoxic drug in the clinical literature. At best, this literature is confusing. There are no reports of ototoxicity of vancomycin in experimental animals, even when it is administered concurrently with ethacrynic acid, a drug known to augment the ototoxic effect of most other otot...
['Acoustic Stimulation', 'Action Potentials', 'Animals', 'Cochlear Microphonic Potentials', 'Drug Synergism', 'Ear, External', 'Gentamicins', 'Guinea Pigs', 'Hair Cells, Auditory', 'Hearing Disorders', 'Reflex', 'Vancomycin']
2,294,943
[['E02.037', 'E02.190.888.030', 'E05.723.136'], ['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['G07.265.216.500.370.223', 'G07.888.250.223', 'G11.561.200.500.370.223'], ['G07.690.773.968.477'], ['A09.246.272'], ['D09.408.051.374'], ['B01.050.150.900.649.313.992.550'], ['A08.675.650.250', 'A08.675....
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]']
1
1
1
1
1
1
1
0
0
0
0
0
0
0
Mechanism of induction of cytochrome P-450ac (P-450j) in chemically induced and spontaneously diabetic rats.
Previous studies demonstrated that a microsomal high-affinity N-nitrosodimethylamine demethylase activity and cytochrome P-450ac (an acetone/ethanol-inducible form) were induced by streptozotocin-induced diabetes in rats. In the present work, the induction was studied in detail in two chemically induced (by streptozoto...
['Animals', 'Antibodies, Monoclonal', 'Body Weight', 'Cytochrome P-450 Enzyme System', 'Diabetes Mellitus, Experimental', 'Enzyme Induction', 'Insulin', 'Isoenzymes', 'Organ Size', 'RNA, Messenger', 'Rats', 'Rats, Inbred Strains']
3,285,794
[['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['C18.452.394.750.074', 'C1...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]']
0
1
1
1
1
0
1
0
0
0
0
0
0
0
Threshold detection using indicator-displacement assays: an application in the analysis of malate in Pinot Noir grapes.
The mathematics for modeling indicator-displacement assay isotherms is presented and contrasted to the classical host-guest binding isotherm. It is shown that the signal response can be tuned to occur closer to 1 equiv of guest relative to a standard binding algorithm. This delay in response leads to a better triggerin...
['Algorithms', 'Color', 'Colorimetry', 'Computer Simulation', 'Indicators and Reagents', 'Malates', 'Models, Statistical', 'Spectrophotometry, Ultraviolet', 'Tartrates', 'Thermodynamics', 'Vitis', 'Wine']
15,137,773
[['G17.035', 'L01.224.050'], ['G01.590.540.199'], ['E05.196.922.250'], ['L01.224.160'], ['D27.720.470.410'], ['D02.241.081.337.463', 'D02.241.511.505'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['D02.241.081.337.864', 'D02.241.081....
['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]']
0
1
0
1
1
0
1
0
0
1
1
0
1
0
The epidemiology of Paget's disease.
Paget's disease is commoner in men and its prevalence increases with age. It has a remarkable geographical localisation. Britain has the highest recorded prevalence. Somewhat lower rates have been recorded in North America, Australia and Western Europe. The disease is rare in Scandinavia. Within Britain there is a loca...
['Age Factors', 'Australia', 'Female', 'Humans', 'Male', 'Osteitis Deformans', 'Sex Factors', 'United Kingdom', 'United States']
7,052,246
[['N05.715.350.075', 'N06.850.490.250'], ['Z01.639.100', 'Z01.678.100.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.692'], ['N05.715.350.675', 'N06.850.490.875'], ['Z01.542.363'], ['Z01.107.567.875']]
['Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]']
0
1
1
0
0
0
0
0
0
0
0
0
1
1
Oncogenic KRAS Targets MUC16/CA125 in Pancreatic Ductal Adenocarcinoma.
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with the 5-year survival rate less than 6%. Previous results indicated that serum levels of CA125 (encoded by MUC16) could be used to predict which groups of pancreatic cancer patients may benefit from surgery. However, the underlying mechanism remains el...
['Animals', 'CA-125 Antigen', 'Carcinoma, Pancreatic Ductal', 'Cell Line, Tumor', 'Humans', 'Membrane Proteins', 'Mice', 'Mice, Transgenic', 'Pancreatic Neoplasms', 'Promoter Regions, Genetic', 'Proto-Oncogene Proteins p21(ras)', 'Proto-Oncogenes', 'Transfection']
28,108,627
[['B01.050'], ['D12.776.395.560.631.050', 'D23.050.285.050.225', 'D23.050.550.325.225', 'D23.101.140.075.225'], ['C04.557.470.200.025.232.750', 'C04.557.470.615.132.750', 'C04.588.274.761.750', 'C04.588.322.475.750', 'C06.301.761.750', 'C06.689.667.625', 'C19.344.421.750'], ['A11.251.210.190', 'A11.251.860.180'], ['B01...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
1
1
1
0
1
0
0
0
0
0
0
0
[Changes in the immune status under the influence of high-frequency electromagnetic radiation].
Experiments on white rats showed that electromagnetic radiation (24 MHz, 400 W/m and 20 W/m) caused leucopenia, reduction of E and EAC rosette formation of lymphocytes, functional activity of neutrophils within 2 months of radiation. No immunosuppressive effect was seen with 24 MHz, 100 W/m radiation, while 400 W/m inh...
['Animals', 'B-Lymphocytes', 'Dose-Response Relationship, Radiation', 'Electromagnetic Phenomena', 'Female', 'Immune System', 'Immune Tolerance', 'Neutrophils', 'Rats', 'Rosette Formation', 'T-Lymphocytes', 'Time Factors']
8,379,142
[['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['G01.358.500'], ['A15.382'], ['G12.535.425'], ['A11.118.637.415.583', 'A11.627.3...
['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]']
1
1
0
0
1
0
1
0
0
0
0
0
1
0
Identification of osteopontin phosphorylation sites involved in bone remodeling and inhibition of pathological calcification.
Osteopontin is a noncollagenous, phosphorylated extracellular glycoprotein, expressed in mineralized and nonmineralized tissues, organs and body fluids. The protein contains an RGD tripeptide cell-binding motif, and is subjected to a variety of posttranslational modifications that play important roles in its multiple b...
['Animals', 'Bone Remodeling', 'Bone and Bones', 'Calcification, Physiologic', 'Calcinosis', 'Casein Kinase II', 'Cattle', 'Escherichia coli', 'Extracellular Matrix', 'Osteogenesis', 'Osteopontin', 'Phosphorylation', 'Protein Processing, Post-Translational', 'Recombinant Proteins', 'Trypsin']
17,615,552
[['B01.050'], ['G11.427.213', 'G16.762.150'], ['A02.835.232', 'A10.165.265'], ['G07.345.155.500', 'G07.345.500.325.377.625.050.500.175', 'G11.427.578.050.500.175'], ['C18.452.174.130'], ['D08.811.913.696.620.682.700.140.600', 'D12.776.476.150.600'], ['B01.050.150.900.649.313.500.380.271'], ['B03.440.450.425.325.300', '...
['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]']
1
1
1
1
0
0
1
0
0
0
0
0
0
0
Lymphatic malformation causing intractable chylorrhagia.
Lymphatic malformation is a developmental error usually noticed at birth or in early childhood. Lesions of the upper leg and lower trunk are the most difficult to remove, because they are often the largest ones encountered and also because they tend to extend proximally into the retroperitoneal tissues. Chyle reflux, u...
['Adolescent', 'Chylous Ascites', 'Diagnostic Imaging', 'Humans', 'Lymphangioma', 'Lymphatic System', 'Male', 'Neoplasm, Residual', 'Postoperative Complications', 'Reoperation', 'Retroperitoneal Space', 'Soft Tissue Neoplasms', 'Surgical Flaps', 'Thigh']
10,744,233
[['M01.060.057'], ['C06.844.200'], ['E01.370.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.375.450'], ['A15.382.520'], ['C04.697.700', 'C23.550.727.700'], ['C23.550.767'], ['E04.690'], ['A01.923.047.025.750'], ['C04.588.839'], ['A10.850.710', 'E07.862.710'], ['A01.378.610.750']]
['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]']
1
1
1
0
1
0
0
0
0
0
0
1
0
0
[Primary treatment of Parkinson's disease: the application of the March 2000 consensus rules in the Nord Pas-de-Calais area].
INTRODUCTION: For Parkinson's disease, the choice of the initial treatment is essentially between L-Dopa and dopaminergic agonists. Selegilin, anticholinergic and amantadine can be used for subjects with moderate symptoms. The first French consensus conference, held in 2000, elaborated decision-making rules which take ...
['Aged', 'Consensus Development Conferences as Topic', 'Female', 'France', 'Guideline Adherence', 'Humans', 'Male', 'Middle Aged', 'Parkinson Disease', 'Practice Guidelines as Topic', 'Retrospective Studies']
15,602,362
[['M01.060.116.100'], ['L01.178.682.759.150', 'N03.540.199.205'], ['Z01.542.286'], ['N04.761.337', 'N05.715.360.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750'], ['N04.761.700.350.650', 'N05.700.350.650'], ['E05.318.372.50...
['Named Groups [M]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
1
0
1
0
0
0
0
0
1
1
1
1
Dysgenesis-induced instability of rosy locus transformation in Drosophila melanogaster: analysis of excision events and the selective recovery of control element deletions.
Utilizing the method of P-M hybrid dysgenesis-mediated gene transfer to insert rosy locus DNA into various chromosomal locations, we recovered a transformed strain that carries an ry+ transposon inserted in or near the scalloped locus in polytene section 13F on the X chromosome. The resultant product, when stabilized, ...
['Animals', 'Chromosome Deletion', 'DNA Restriction Enzymes', 'DNA Transposable Elements', 'Drosophila melanogaster', 'Female', 'Male', 'Transformation, Genetic', 'Xanthine Dehydrogenase']
2,981,758
[['B01.050'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330...
['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]']
0
1
1
1
0
0
1
0
0
0
0
0
0
0
Intravenous immunoglobulin therapy for prevention of infection in high-risk premature infants: report of a multicenter, double-blind study.
The effectiveness of intravenously administered immunoglobulin (Ig) therapy for prophylaxis of infection was evaluated in high-risk preterm infants. Two hundred thirty-five premature newborns were randomly assigned, in a double-blind controlled trial, to treatment and placebo groups. Thirty-five infants (29%) of the Ig...
['Cross Infection', 'Double-Blind Method', 'Drug Evaluation', 'Gestational Age', 'Humans', 'Immunoglobulin G', 'Infant, Newborn', 'Infant, Premature, Diseases', 'Infusions, Intravenous', 'Intensive Care Units, Neonatal', 'Risk Factors']
1,881,720
[['C01.248', 'C23.550.291.875.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E05.290.625', 'E05.337.425'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', '...
['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Named Groups [M]']
0
1
1
1
1
0
1
0
0
0
0
1
1
0
Identifying cognitive preferences for attractive female faces: an event-related potential experiment using a study-test paradigm.
In this experiment, sensitivity to female facial attractiveness was examined by comparing event-related potentials (ERPs) in response to attractive and unattractive female faces within a study-test paradigm. Fourteen heterosexual participants (age range 18-24 years, mean age 21.67 years) were required to judge 84 attra...
['Adolescent', 'Beauty', 'Choice Behavior', 'Evoked Potentials', 'Face', 'Facial Expression', 'Female', 'Humans', 'Male', 'Reaction Time', 'Young Adult']
21,805,493
[['M01.060.057'], ['F02.463.785.477.304', 'K01.752.210.304'], ['F02.463.785.373.346'], ['G07.265.216.500', 'G11.561.200.500'], ['A01.456.505'], ['E01.370.600.225', 'F01.145.209.530.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['M01.060.116.815']]
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Humanities [K]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]']
1
1
0
0
1
1
1
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1
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Neutrophils ameliorate lung injury and the development of severe disease during influenza infection.
The clinical response to influenza infection ranges from mild disease to severe pneumonia and it remains unclear whether the inflammatory response to infection is protective or pathogenic. We have defined a novel role for neutrophils in ameliorating lung injury during influenza infection, thereby limiting development o...
['Animals', 'Influenza A Virus, H3N2 Subtype', 'Mice', 'Mice, Inbred C57BL', 'Neutrophils', 'Orthomyxoviridae Infections', 'Pneumonia, Viral']
19,917,678
[['B01.050'], ['B04.820.480.968.405.400.300'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.689'], ['C01.925.782.62...
['Organisms [B]', 'Anatomy [A]', 'Diseases [C]']
1
1
1
0
0
0
0
0
0
0
0
0
0
0
Adolescent and young adult understanding of the differences between chlamydia, HIV, and AIDS.
OBJECTIVE: To explore young people's understanding of the differences between Chlamydia, HIV, and AIDS. METHODS. Participants from a hospital-based adolescent clinic completed a self-administered written survey. Three questions assessed participants' understanding of the differences between Chlamydia, HIV, and AIDS.RES...
['Acquired Immunodeficiency Syndrome', 'Adolescent', 'Age Factors', 'Chlamydia Infections', 'Comprehension', 'Female', 'HIV Infections', 'Health Knowledge, Attitudes, Practice', 'Health Surveys', 'Humans', 'Logistic Models', 'Male', 'Surveys and Questionnaires', 'Young Adult']
23,444,267
[['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C...
['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]']
0
1
1
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1
1
0
0
0
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1
1
0
Recurrence of iris melanoma after proton beam therapy.
BACKGROUND/AIMS: A retrospective service evaluation to report on recurrence of iris melanoma after proton beam therapy (PBT).METHODS: The cohort comprised 150 consecutive eyes with iris melanoma treated with proton beam radiotherapy. Treatment consisted of 53.1 Gy of proton beam irradiation delivered in four fractions ...
['Dose Fractionation, Radiation', 'Eye Enucleation', 'Follow-Up Studies', 'Humans', 'Iris Neoplasms', 'Melanoma', 'Neoplasm Recurrence, Local', 'Proton Therapy', 'Retrospective Studies', 'Visual Acuity']
24,414,401
[['E02.815.639.200'], ['E04.540.429'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.364.978.400', 'C11.319.494.400', 'C11.941.375.375', 'C11.941.855.400'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04...
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]']
0
1
1
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0
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1
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