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Lifestyle-adjusted function: variation beyond BADL and IADL competencies. | PURPOSE: Using the Activity Card Sort (ACS), we derived a measure of lifestyle-adjusted function and examined the distribution of this measure and its correlates in a community sample of older adults at risk for disability transitions.DESIGN AND METHODS: Participants in the Sources of Independence in the Elderly projec... | ['Activities of Daily Living', 'Aged', 'Aged, 80 and over', 'Aging', 'Disabled Persons', 'Female', 'Humans', 'Life Style', 'Male', 'Q-Sort'] | 19,506,030 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['M01.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458'], ['F04.513.636']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A scalable admission control scheme based on time label. | Resource reservation protocols allow communicating hosts to reserve resources such as bandwidth to offer guaranteed service. However, current resource reservation architectures do not scale well for a large number of flows. In this paper, we present a simple reservation protocol and a scalable admission control algorit... | ['Algorithms', 'Computer Simulation', 'Information Storage and Retrieval', 'Internet', 'Models, Statistical', 'Quality Assurance, Health Care', 'Quality Control', 'Signal Processing, Computer-Assisted', 'Time Factors'] | 15,495,337 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['L01.313.500.750.280', 'L01.470'], ['L01.224.230.110.500'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['N04.761.700', 'N05.700'], ['J01.897.608'], ['L01.224.800'], ['G01.910.857']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Proteoglycan metabolism in tissue-cultured human articular cartilage. Influence of niflumic acid. | Proteoglycan metabolism was investigated in tissue-cultured human cartilage. Normal cartilage obtained from a normal joint showed improving accumulation rates for 35S-labelled proteoglycans over a 3-6 weeks' period. The loss of newly synthesized molecules in the nutrient media was low and constant throughout culture. A... | ['Adolescent', 'Cartilage, Articular', 'Cells, Cultured', 'Glycosaminoglycans', 'Humans', 'Knee Joint', 'Male', 'Middle Aged', 'Nicotinic Acids', 'Niflumic Acid', 'Proteoglycans'] | 2,402,599 | [['M01.060.057'], ['A02.165.407.150', 'A02.835.583.192'], ['A11.251'], ['D09.698.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['M01.060.116.630'], ['D03.066.515', 'D03.383.725.547'], ['D02.241.223.100.050.400.200.777', 'D02.455.426.559.389.127.020.906.750.777', 'D03.066.515.550', 'D03.38... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Peripheral GLP-1 gastroprotection against ethanol: the role of exendin, NO, CGRP, prostaglandins and blood flow. | The aim of this study was to investigate the effects of peripherally injected glucagon like peptide-1 (GLP-1) on ethanol-induced gastric mucosal damage and the mechanisms included in the effect. Absolute ethanol was administered through an orogastric cannula right after the injection of GLP-1 (1, 10, 100, 1000 or 10,00... | ['Animals', 'Calcitonin Gene-Related Peptide', 'Ethanol', 'Gastric Mucosa', 'Glucagon-Like Peptide 1', 'Indomethacin', 'Male', 'NG-Nitroarginine Methyl Ester', 'Nitric Oxide', 'Peptide Fragments', 'Prostaglandins', 'Rats', 'Rats, Sprague-Dawley', 'Regional Blood Flow'] | 18,926,859 | [['B01.050'], ['D12.644.400.097', 'D12.776.631.650.097'], ['D02.033.375'], ['A03.556.875.875.440', 'A10.615.550.291'], ['D06.472.317.680.500.500'], ['D03.633.100.473.420'], ['D12.125.068.050.525', 'D12.125.095.104.525'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['D12.644.541'], ['D1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Nuclear scintigraphic assessment of radiation-induced intestinal dysfunction. | Radiation-induced damage to the intestine can be measured by abnormalities in the absorption of various nutrients. Changes in intestinal absorption occur after irradiation because of loss of the intestinal absorptive surface and a consequent decrease in active transport. In our study, the jejunal absorption of (99m)Tc-... | ['Animals', 'Female', 'Intestinal Absorption', 'Jejunum', 'Mice', 'Mice, Inbred C3H', 'Radionuclide Imaging', 'Radiopharmaceuticals', 'Sodium Pertechnetate Tc 99m'] | 10,629,615 | [['B01.050'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500', 'G07.690.725.015.500.374.500', 'G10.261.353.500'], ['A03.556.124.684.500', 'A03.556.249.750'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.388', 'B01.050.150.900.649.313.992.635.505.500.400.388'], ['E01.37... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinico-immunologic characteristics of acute toxic-allergic reactions to drugs and current methods for their treatment]. | The paper is concerned with clinicoimmunological and allergological characterization of 29 cases of acute toxic allergic reactions (ATAR) to drugs. Four degrees of severity of disease were identified; the most severe form was toxic epidermal necrolysis caused by the use of sulfanilamides and pyrazolones in patients wit... | ['Acute Disease', 'Adolescent', 'Adult', 'Child', 'Combined Modality Therapy', 'Drug Hypersensitivity', 'Drug-Related Side Effects and Adverse Reactions', 'Female', 'Hospitalization', 'Humans', 'Male', 'Middle Aged', 'Stevens-Johnson Syndrome', 'Time Factors'] | 3,222,755 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E02.186'], ['C20.543.206', 'C25.100.468'], ['C25.100'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C07.465.864.500', 'C17.800.174.600.900', 'C17.800.229.400.683', 'C17.800.865.475.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Quantitative trait loci mapping for the shear force value in breast muscle of F2 chickens. | The shear force value is one of the major traits that determine meat quality. In the present study, we performed QTL analysis for chicken breast muscle shear force value at 7 wk of age using 545 single nucleotide polymorphism (SNP) markers developed via restriction-site associated DNA sequencing (RAD-seq). An F2 resour... | ['Animals', 'Biomechanical Phenomena', 'Chickens', 'Female', 'Male', 'Meat', 'Pectoralis Muscles', 'Quantitative Trait Loci'] | 30,329,107 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G07.203.300.600', 'J02.500.600'], ['A02.633.567.775'], ['G05.360.340.024.380.937']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Study on the relationship between smoking, alcohol intake and hyperlipidemia in fishermen]. | OBJECTIVE: To identify the relationship between smoking, alcohol intake and hyperlipidemia in fishermen.METHODS: 115 fishermen were randomly recruited and divided into case and control groups according to the result of blood lipoprotein. A questionnaire was used to record general information and the history of smoking ... | ['Adolescent', 'Adult', 'Alcohol Drinking', 'Case-Control Studies', 'Cholesterol', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Fisheries', 'Humans', 'Hyperlipidemias', 'Logistic Models', 'Male', 'Middle Aged', 'Occupational Health', 'Risk Factors', 'Smoking', 'Surveys and Questionnaires'] | 14,761,628 | [['M01.060.057'], ['M01.060.116'], ['F01.145.317.269'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['D04.210.50... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Isolation and Characterization of Cyclic C33 | Three cyclic C33 botryococcenes and one new trimethylsqualene isomer were isolated from the B race, Showa (Berkeley) strain of Botryococcus braunii, which is known to produce large amounts of isoprenoid hydrocarbons ranging in carbon number from 30 to 34. Their purity was determined by GC-MS, and structures were charac... | ['Chlorophyta', 'Gas Chromatography-Mass Spectrometry', 'Isomerism', 'Molecular Structure', 'Nuclear Magnetic Resonance, Biomolecular', 'Squalene', 'Terpenes'] | 28,333,447 | [['B01.650.940.150'], ['E05.196.181.349.500', 'E05.196.566.500'], ['G02.111.570.685', 'G02.607.445'], ['G02.111.570', 'G02.466'], ['E05.196.867.519.550'], ['D02.455.326.271.665.806', 'D02.455.849.919.681'], ['D02.455.849']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prognostic evaluation for squamous cell carcinomas of the lower thoracic esophagus treated with three-field lymph node dissection. | OBJECTIVE: The efficacy of esophagectomy with three-field lymph node dissection in surgical treatment for patients with squamous cell carcinomas of the lower thoracic esophagus remains controversial. This report documents the outcomes of this surgical procedure for a large series.METHODS: From February 1986 to November... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Squamous Cell', 'Esophageal Neoplasms', 'Esophagectomy', 'Female', 'Humans', 'Lymph Node Excision', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Prognosis', 'Retrospective Studies', 'Survival Rate'] | 11,404,147 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['E04.210.346'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.446'], ['C04.697.650.560', 'C23.550... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pitfalls to avoid: the Australian experience. | In this paper the major health problems facing Australia's Aboriginal population are reviewed and an attempt is made to assess the genetic and environmental, social and cultural factors to which they may be attributed. Among Aborigines living in remote areas under semi-tribal conditions, recent improvements in health, ... | ['Adult', 'Age Factors', 'Anomie', 'Attitude to Health', 'Australia', 'Family Characteristics', 'Feeding Behavior', 'Genetics, Population', 'Health Education', 'Health Services', 'Health Surveys', 'Humans', 'Infant', 'Infant Mortality', 'Infant, Newborn', 'Life Style', 'Middle Aged', 'Mortality', 'Oceanic Ancestry Grou... | 244,414 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.145.813.093', 'I01.880.853.450.283'], ['F01.100.150', 'N05.300.150'], ['Z01.639.100', 'Z01.678.100.373'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N01.824.308', 'N06.850.505.400.400'], ['F01.145.113.547', 'F01.145.407', 'G0... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseas... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Vasogenic edema characterizes pediatric acute disseminated encephalomyelitis. | INTRODUCTION: MR imaging criteria for diagnosing acute disseminated encephalomyelitis (ADEM) have not been clearly established. Due to the wide spectrum of differential considerations, new imaging features allowing early and accurate diagnosis for ADEM are needed. We hypothesized that ADEM lesions would be characterize... | ['Adolescent', 'Age Factors', 'Brain Edema', 'Child', 'Child, Preschool', 'Diffusion Magnetic Resonance Imaging', 'Encephalomyelitis, Acute Disseminated', 'Female', 'Humans', 'Male', 'Reproducibility of Results', 'Retrospective Studies', 'Time Factors'] | 24,854,347 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['C10.228.140.187'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.350.825.500.150'], ['C10.114.375.225', 'C10.228.140.695.562.225', 'C10.314.350.225', 'C20.111.258.250.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.370.725', 'E05.337.851', ... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Aqueous or lipid components of atherosclerotic lesion increase macrophage oxidation and lipid accumulation. | INTRODUCTION AND OBJECTIVE: Understanding the interactions among atherosclerotic plaque components and arterial macrophages, is essential for elucidating the mechanisms involved in the development of atherosclerosis. We assessed the effects of lesion extracts on macrophages.METHODS: Mouse peritoneal macrophages from at... | ['Animals', 'Aorta', 'Atherosclerosis', 'Cells, Cultured', 'Humans', 'Lipid Metabolism', 'Macrophages, Peritoneal', 'Mice', 'Mice, Knockout', 'Oxidation-Reduction', 'Oxidative Stress'] | 27,114,099 | [['B01.050'], ['A07.015.114.056'], ['C14.907.137.126.307'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G03.458'], ['A11.329.372.630', 'A11.627.482.630', 'A11.733.397.630', 'A15.382.670.522.630', 'A15.382.680.397.630'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.05... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Turnip Mosaic Virus Is a Second Example of a Virus Using Transmission Activation for Plant-to-Plant Propagation by Aphids. | Cauliflower mosaic virus (CaMV; family Caulimoviridae) responds to the presence of aphid vectors on infected plants by forming specific transmission morphs. This phenomenon, coined transmission activation (TA), controls plant-to-plant propagation of CaMV. A fundamental question is whether other viruses rely on TA. Here... | ['Animals', 'Aphids', 'Brassica rapa', 'Hydrogen Peroxide', 'Lanthanum', 'Plant Diseases', 'Potyvirus'] | 30,760,573 | [['B01.050'], ['B01.050.500.131.617.412.165'], ['B01.650.940.800.575.912.250.157.200.277'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D01.268.558.362.500', 'D01.552.550.399.500'], ['G15.610'], ['B04.715.464.600', 'B04.715.635.600', 'B04.820.578.782.600']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diagnosis of congenital syphilis by immunofluorescence following fetal death in utero. | The etiology of fetal death may be difficult to identify, particularly with the presence of marked fetal maceration and autolysis. Immunofluorescence with human antitreponemal antibody was used in this case to establish a diagnosis of congenital syphilis. | ['Adult', 'Female', 'Fetal Death', 'Fluorescent Antibody Technique', 'Humans', 'Liver', 'Pregnancy', 'Syphilis, Congenital'] | 3,895,941 | [['M01.060.116'], ['C13.703.223', 'C23.550.260.585'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['G08.686.784.769'], ['C01.150.252.400.794.840.500.937', 'C01.150.2... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Laparoscopic gastroenterostomy for duodenal obstruction. | BACKGROUND: It is not yet clear where laparoscopic procedures will fit into the armamentarium of the surgeon. Over the past decade, there has been a clear trend toward minimally invasive procedures for palliation of inoperable cancer. Traditionally, when duodenal obstruction occurs secondary to a disease process, gastr... | ['Aged', 'Aged, 80 and over', 'Cholecystostomy', 'Duodenal Obstruction', 'Female', 'Follow-Up Studies', 'Gastroenterostomy', 'Humans', 'Jejunostomy', 'Laparoscopy', 'Male', 'Middle Aged', 'Palliative Care', 'Postoperative Complications', 'Postoperative Period', 'Reoperation', 'Survival Rate', 'Treatment Outcome'] | 7,538,268 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.035.195', 'E04.210.120.195'], ['C06.405.469.275.395', 'C06.405.469.531.311'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.035.398', 'E04.210.457'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.210.338.523... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effect of diclofenac and nefopam on postoperative dental pain. | Eighty-two outpatients who received general anaesthesia for surgical removal of maxillary or mandibular third molars were given either diclofenac 75 mg or nefopam 20 mg intramuscularly for postoperative pain control. They and the control group were also allowed oral paracetamol as required. The results showed that ther... | ['Adult', 'Ambulatory Surgical Procedures', 'Anesthesia, Dental', 'Anesthesia, General', 'Diclofenac', 'Double-Blind Method', 'Female', 'Humans', 'Male', 'Nefopam', 'Oxazocines', 'Pain, Postoperative', 'Randomized Controlled Trials as Topic', 'Tooth Extraction'] | 2,186,651 | [['M01.060.116'], ['E04.030'], ['E03.155.141', 'E06.045'], ['E03.155.197'], ['D02.241.223.601.210'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.113.767.500'], ['D03.383.113.767'], ['C23.550.767.700', 'C23.888.592.612.8... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Categorizing and assessing comprehensive drivers of provider behavior for optimizing quality of health care. | Inadequate quality of care in healthcare facilities is one of the primary causes of patient mortality in low- and middle-income countries, and understanding the behavior of healthcare providers is key to addressing it. Much of the existing research concentrates on improving resource-focused issues, such as staffing or ... | ['Child Health', 'Female', 'Health Personnel', 'Humans', 'India', 'Infant, Newborn', 'Male', 'Quality of Health Care'] | 30,995,274 | [['N01.400.225'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['M01.060.703.520'], ['N04.761', 'N05.715']] | ['Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
D-Glucose enhancement of water reabsorption in proximal tubule of the rat kidney. | Water reabsorption in the proximal convoluted tubule of the rat kidney was examined by in vivo microperfusion techniques in order to examine the effect of D-glucose within the tubular lumen. When tubules were perfused with a balanced artificial solution containing Na, K, Cl, HCO3, urea, and D-glucose, absolute reabsorp... | ['Animals', 'Deoxyglucose', 'Glucose', 'Kidney Tubules, Proximal', 'Male', 'Methylglucosides', 'Phlorhizin', 'Rats', 'Sodium Chloride', 'Water-Electrolyte Balance'] | 970,456 | [['B01.050'], ['D09.254.229'], ['D09.947.875.359.448'], ['A05.810.453.736.560.570'], ['D09.408.348.500', 'D09.408.514.622'], ['D09.408.702'], ['B01.050.150.900.649.313.992.635.505.700'], ['D01.210.450.150.875', 'D01.857.650'], ['G02.111.635.500', 'G03.615.500', 'G07.410.810.500']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
3'-UTR-mediated post-transcriptional regulation of cancer metastasis: beginning at the end. | Epithelial-mesenchymal transition (EMT) and the underlying mechanisms and signaling pathways regulating such transitions have generated a lot of interest among cancer researchers. Much of this can be attributed to the apparent similarities in the molecular processes regulating embryonic EMT that can be recapitulated du... | ["3' Untranslated Regions", 'Epithelial-Mesenchymal Transition', 'Gene Expression Regulation, Neoplastic', 'Heterogeneous-Nuclear Ribonucleoproteins', 'Humans', 'Neoplasm Metastasis', 'Neoplasms', 'Peptide Elongation Factor 1', 'Proto-Oncogene Proteins c-akt', 'RNA, Messenger', 'Signal Transduction', 'Transforming Grow... | 21,654,215 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['G04.356.500'], ['G05.308.370'], ['D12.776.157.725.813.750', 'D12.776.664.962.813.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650', 'C23.550.727.650'], ['C04'], ['D08.811.277... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Suppression of survival signalling pathways by the phosphatase PHLPP. | The recently discovered pleckstrin homology (PH) domain leucine-rich repeat protein phosphatase (PHLPP) family is emerging as a central component in suppressing cell survival pathways. Originally discovered in a rational search for a phosphatase that directly dephosphorylates and inactivates Akt, PHLPP is now known to ... | ['Cell Survival', 'Humans', 'Male', 'Mutation', 'Nuclear Proteins', 'Phosphatidylinositol 3-Kinases', 'Phosphoprotein Phosphatases', 'Prostatic Neoplasms', 'Proto-Oncogene Proteins c-akt', 'Signal Transduction', 'Tumor Suppressor Proteins'] | 22,340,730 | [['G04.346'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.590'], ['D12.776.660'], ['D08.811.913.696.620.500'], ['D08.811.277.352.650.625'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['D08.811.913.696.620.682.700.755', 'D12.776.476.565', 'D12.776.624.664.700.168'], ... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of perhexiline maleate on asialo-orosomucoid receptor endocytosis and recycling in HTC cells. | Perhexiline is a lysosomotropic agent which has proved to be very valuable to certain patients suffering from angina pectoris. However long-term administration of the drug may induce hepato- and neuro-toxicity. Using HTC cells (a rat hepatoma-derived cell line) whose plasma membranes were labeled with NaB[3H]4 after ox... | ['Animals', 'Asialoglycoprotein Receptor', 'Cells, Cultured', 'Endocytosis', 'Kinetics', 'Neuraminidase', 'Orosomucoid', 'Perhexiline', 'Rats', 'Receptors, Immunologic'] | 2,616,900 | [['B01.050'], ['D12.776.503.280.124', 'D12.776.543.750.024'], ['A11.251'], ['G04.417'], ['G01.374.661', 'G02.111.490'], ['D08.811.277.450.692'], ['D12.776.124.050.600', 'D12.776.124.790.106.640', 'D12.776.377.715.085.640', 'D12.776.395.560.742'], ['D03.383.621.644'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.7... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Changes in motor cortical activity during visuomotor adaptation. | We examined neuronal activity in three motor cortical areas while a rhesus monkey adapted to novel visuomotor transforms. The monkey moved a joystick that controlled a cursor on a video screen. Each trial began with the joystick centered. Next, the cursor appeared in one of eight positions, arranged in a circle around ... | ['Adaptation, Physiological', 'Animals', 'Behavior, Animal', 'Brain Mapping', 'Conditioning, Psychological', 'Electromyography', 'Macaca mulatta', 'Male', 'Motor Cortex', 'Motor Skills', 'Movement', 'Oculomotor Muscles', 'Photic Stimulation', 'Psychomotor Performance'] | 9,746,135 | [['G07.025', 'G16.012.500'], ['B01.050'], ['F01.145.113'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.425.179'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tibial tenderness identifies secondary hyperparathyroidism responding to high-dose vitamin D in Pakistani women. | OBJECTIVE: To assess the utility of anterior tibial tenderness (ATT) measured by visual analogue scoring (VAS) as a clinical diagnostic tool for vitamin D deficiency in a high-risk population of Pakistani women.METHODS: ATT was measured by VAS in 75 premenopausal women age 17 to 56 years (mean, 41.3 years) with general... | ['Adolescent', 'Adult', 'Child', 'Female', 'Humans', 'Hyperparathyroidism, Secondary', 'Middle Aged', 'Pakistan', 'Tibia', 'Vitamin D', 'Vitamin D Deficiency', 'Young Adult'] | 23,425,639 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.642.355.480'], ['M01.060.116.630'], ['Z01.252.245.723'], ['A02.835.232.043.650.883'], ['D04.210.500.812.768'], ['C18.654.521.500.133.770'], ['M01.060.116.815']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Primary malignant fibrous histiocytoma of the liver MRI findings. | Primary malignant fibrous histiocytoma (MFH) is an unusual tumor which involves the deep fascia or skeletal muscles of the extremities or retroperitoneum. It rarely arises in the liver and, to our knowledge, the MRI appearance of primary MFH of the liver has never been reported. We present a patient with primary MFH of... | ['Histiocytoma, Benign Fibrous', 'Humans', 'Liver', 'Liver Neoplasms', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Tomography, X-Ray Computed'] | 8,380,881 | [['C04.557.450.565.590.425.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.8... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Adsorption of microcystin-LR from water with iron oxide nanoparticles. | Adsorption of microcystin-LR (MC-LR) from water using iron oxide (alpha-Fe2O3) nanoparticles was investigated in this study. Adsorption of MC-LR adsorption was well-described by a pseudo second order kinetics model and Freundlich and Langmuir isotherm equations at 15 to 35 degrees C. Thermodynamic analysis showed that ... | ['Adsorption', 'Ferric Compounds', 'Hydrogen-Ion Concentration', 'Marine Toxins', 'Metal Nanoparticles', 'Microcystins', 'Time Factors', 'Water Pollutants, Chemical'] | 22,876,478 | [['G01.030', 'G02.020'], ['D01.490.100'], ['G02.300'], ['D23.946.580'], ['J01.637.512.600.500'], ['D04.345.566.447', 'D12.644.641.447', 'D23.946.123.574'], ['G01.910.857'], ['D27.888.284.903.655']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
2-Nitroimidazole-tricarbocyanine conjugate as a near-infrared fluorescent probe for in vivo imaging of tumor hypoxia. | We developed a novel near-infrared (NIR) fluorescent probe, GPU-167, for in vivo imaging of tumor hypoxia. GPU-167 comprises a tricarbocyanine dye as an NIR fluorophore and two 2-nitroimidazole moieties as exogenous hypoxia markers that undergo bioreductive activation and then selective entrapment in hypoxic cells. Aft... | ['Animals', 'Carbocyanines', 'Cell Hypoxia', 'Fluorescent Dyes', 'Mice', 'Mice, Nude', 'Neoplasms', 'Nitroimidazoles', 'Spectroscopy, Near-Infrared'] | 22,335,430 | [['B01.050'], ['D02.455.326.397.300'], ['G03.197.300', 'G04.270.300'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.500'], ['C04'], ['D02.640.672', 'D03.383.129.308.658'], ['E01.370.350.750', 'E05.196.867.851']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular characterization and expression analysis of AMPK á subunit isoform genes from Scophthalmus maximus responding to salinity stress. | AMP-activated protein kinase (AMPK) is a highly conserved and multi-functional protein kinase that plays important roles in both intracellular energy balance and cellular stress response. In the present study, molecular characterization, tissue distribution and gene expression levels of the AMPK á1 and á2 genes from tu... | ['AMP-Activated Protein Kinases', 'Amino Acid Sequence', 'Animals', 'Base Sequence', 'DNA, Complementary', 'Fish Proteins', 'Flatfishes', 'Gene Expression', 'Gills', 'Phylogeny', 'Protein Isoforms', 'RNA, Messenger', 'Salinity', 'Sodium-Potassium-Exchanging ATPase', 'Stress, Physiological'] | 27,380,381 | [['D08.811.913.696.620.682.700.085', 'D12.644.360.062', 'D12.776.476.062'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D12.776.325'], ['B01.050.150.900.493.418'], ['G... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Trends in salmonella food poisoning in England and Wales 1941-72. | Cattle and pig herds and flocks of domestic fowl have formed the main reservoir of human salmonella food poisoning in England and Wales from 1941 to 1972. Changes in the incidence of human salmonella food poisoning and in the serotypes of salmonellas isolated from human infections are shown to have been associated with... | ['Animals', 'Cattle', 'Cattle Diseases', 'Eggs', 'England', 'Food Microbiology', 'Humans', 'Meat', 'Poultry', 'Poultry Diseases', 'Poultry Products', 'Salmonella', 'Salmonella Food Poisoning', 'Salmonella Infections', 'Salmonella Infections, Animal', 'Serotyping', 'Sheep', 'Sheep Diseases', 'Swine', 'Swine Diseases', '... | 1,054,731 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['G07.203.300.470', 'J02.500.470'], ['Z01.542.363.300'], ['H01.158.273.540.274.332', 'J01.576.423.850.730.500.249.300', 'N06.850.425.200', 'N06.850.460.400.300', 'N06.850.601.500.249.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.300... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
The atomic structure of the virally encoded antifungal protein, KP6. | Killer toxins are produced by several genera of yeast and filamentous fungi. A small proportion of Ustilago maydis strains produce killer toxins, to which they are resistant, but sensitive strains are the majority in the wild populations. There are three killer types (P1, P4 and P6) that secrete KP1, KP4 and KP6 toxins... | ['Amino Acid Sequence', 'Crystallography, X-Ray', 'Fungal Proteins', 'Models, Biological', 'Models, Molecular', 'Molecular Sequence Data', 'Mycotoxins', 'Protein Biosynthesis', 'Protein Conformation', 'Protein Processing, Post-Translational', 'Sequence Homology, Amino Acid', 'Ustilago'] | 23,219,466 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.196.309.742.225'], ['D12.776.354'], ['E05.599.395'], ['E05.599.595'], ['L01.453.245.667'], ['D23.946.587'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['G02.111.570.820.709'], ['G02.111.660.871.790.600', 'G02.111.691.600', 'G03.734.871.790.600', 'G05.308.670.60... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Supraventricular tachycardia in children: clinical features, response to treatment, and long-term follow-up in 217 patients. | We reviewed the records of 217 children whose first episode of supraventricular tachycardia occurred before 18 years (median age 24 months). There were 112 males and 105 females. Of the 49 with congenital heart disease, SVT began before any operation in 26 and greater than 2 weeks postoperatively in 23. Wolf-Parkinson-... | ['Adolescent', 'Anti-Arrhythmia Agents', 'Child', 'Child, Preschool', 'Digoxin', 'Female', 'Follow-Up Studies', 'Heart Failure', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Tachycardia', 'Wolff-Parkinson-White Syndrome'] | 7,229,788 | [['M01.060.057'], ['D27.505.954.411.097'], ['M01.060.406'], ['M01.060.406.448'], ['D04.210.500.155.580.130.500.436', 'D04.210.500.155.580.130.688', 'D09.408.180.261.436'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Soldier morphogenesis in the damp-wood termite is regulated by the insulin signaling pathway. | Eusocial insects exhibit various morphological castes associated with the division of labor within a colony. Termite soldiers possess defensive traits including mandibles that are greatly exaggerated and enlarged, as compared to termite reproductives and workers. The enlarged mandibles of soldiers are known to result f... | ['Animals', 'In Situ Hybridization', 'Insulin', 'Isoptera', 'Juvenile Hormones', 'Morphogenesis', 'Signal Transduction', 'Wood'] | 23,703,784 | [['B01.050'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['B01.050.500.131.617.485'], ['D06.472.445.573.666'], ['G07.345.500'], ['G02.111.820', 'G04.835'], ['A18.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Mucin- and carbohydrate-stimulated adhesion and subproteome changes of the probiotic bacterium Lactobacillus acidophilus NCFM. | Adhesion to intestinal mucosa is a crucial property for probiotic bacteria. Adhesion is thought to increase host-bacterial interactions, thus potentially enabling health benefits to the host. Molecular events connected with adhesion and surface proteome changes were investigated for the probiotic Lactobacillus acidophi... | ['Bacterial Adhesion', 'Bacterial Proteins', 'Carbohydrates', 'HT29 Cells', 'Humans', 'Lactobacillus acidophilus', 'Mucins', 'Peptide Elongation Factor G', 'Probiotics', 'Proteome', 'Pyruvate Kinase'] | 28,533,178 | [['G06.099.050'], ['D12.776.097'], ['D09'], ['A11.251.210.190.475', 'A11.251.860.180.475', 'A11.436.365'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.353.750.450.475.100', 'B03.510.460.400.410.475.475.100', 'B03.510.550.450.475.100'], ['D12.776.395.560.631'], ['D08.811.277.040.330.300.100.200', 'D12.776.157... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Impact of weight gain on the evolution and regression of prediabetes: a quantitative analysis. | BACKGROUND/OBJECTIVES: The quantitative impact of weight gain on prediabetic glucose dysregulation remains unknown; only one study quantitated the impact of weight loss. We quantified the impact of weight gain on the evolution and regression of prediabetes (PDM).SUBJECTS/METHODS: In 4234 subjects without diabetes, usin... | ['Adult', 'Blood Glucose', 'Body Mass Index', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Glucose Tolerance Test', 'Humans', 'Logistic Models', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Odds Ratio', 'Prediabetic State', 'Retrospective Studies', 'Risk Factors', 'Sex Factors', 'Weight Gain'] | 27,406,163 | [['M01.060.116'], ['D09.947.875.359.448.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.550.291.656'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mid-term results of a modified self-growing rod technique for the treatment of early-onset scoliosis. | AIMS: To report the mid-term results of a modified self-growing rod (SGR) technique for the treatment of idiopathic and neuromuscular early-onset scoliosis (EOS).METHODS: We carried out a retrospective analysis of 16 consecutive patients with EOS treated with an SGR construct at a single hospital between September 2008... | ['Age Factors', 'Bone Nails', 'Child', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Retrospective Studies', 'Scoliosis', 'Spinal Fusion', 'Thoracic Vertebrae'] | 33,135,451 | [['N05.715.350.075', 'N06.850.490.250'], ['E07.695.370.249', 'E07.858.442.660.460.249', 'E07.858.690.725.460.249'], ['M01.060.406'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.75... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The laboratory diagnosis of plasma cell myeloma and related disorders. | Plasma cell myeloma constitutes the commonest primary malignant tumor affecting the skeleton of the adult. It is also one of several forms of monoclonal gammopathy that include Waldenstr?m's macroglobulinemia, the heavy chain diseases, "benign" (nonprogressive, asymptomatic) monoclonal gammopathy, and primary amyloidos... | ['Bence Jones Protein', 'Biopsy', 'Blood Cell Count', 'Blood Protein Disorders', 'Blood Protein Electrophoresis', 'Bone Marrow', 'Humans', 'Immunodiffusion', 'Immunoelectrophoresis', 'Immunoglobulins', 'Multiple Myeloma', 'Plasma Cells'] | 109,804 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Histologic Evaluation of Micronized AlloDerm After Injection Laryngoplasty in a Rabbit Model. | OBJECTIVES/HYPOTHESIS: Micronized AlloDerm is a commonly used injectable material for injection laryngoplasty; however, the histologic response to laryngeal implantation and resorption rate over time have not been elucidated. This study aimed to evaluate the in vivo response of micronized AlloDerm over time after laryn... | ['Animals', 'Collagen', 'Disease Models, Animal', 'Injections', 'Laryngoplasty', 'Rabbits', 'Recurrent Laryngeal Nerve', 'Time Factors', 'Vocal Cord Paralysis'] | 27,578,401 | [['B01.050'], ['D05.750.078.280', 'D12.776.860.300.250'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.319.267.530'], ['E04.580.371'], ['B01.050.150.900.649.313.968.700'], ['A08.800.050.050.925.450.700', 'A08.800.050.600.825.450.700', 'A08.800.800.060.920.450.700', 'A08.800.800.120.900.450.700'], ['G01.910.857'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Uridine diphosphate glucuronosyltransferase isoform-dependent regiospecificity of glucuronidation of flavonoids. | The objective of this study was to determine the regiospecificity of the important uridine diphosphate glucuronosyltransferase (UGT) isoforms responsible for the glucuronidation of flavones and flavonols. We systematically studied the glucuronidation of 13 flavonoids (7 flavones and 6 flavonols, with hydroxyl groups at... | ['Flavonoids', 'Glucuronides', 'Glucuronosyltransferase', 'Humans', 'Isoenzymes', 'Recombinant Proteins', 'Substrate Specificity'] | 21,413,806 | [['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['D02.241.081.844.915.162.500', 'D02.241.152.811.162.750', 'D02.241.511.902.915.162.750', 'D09.811.922.162.750'], ['D08.811.913.400.450.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.348', 'D12.776.800.300'], ['D12.776.828'], ['G02.111.835']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Self-adaptive genetic algorithms with simulated binary crossover. | Self-adaptation is an essential feature of natural evolution. However, in the context of function optimization, self-adaptation features of evolutionary search algorithms have been explored mainly with evolution strategy (ES) and evolutionary programming (EP). In this paper, we demonstrate the self-adaptive feature of ... | ['Algorithms', 'Bias', 'Biological Evolution', 'Computer Simulation', 'Genetics, Population', 'Models, Genetic', 'Models, Statistical', 'Mutation'] | 11,382,356 | [['G17.035', 'L01.224.050'], ['N05.715.350.150', 'N06.850.490.500'], ['G05.045', 'G16.075'], ['L01.224.160'], ['H01.158.273.343.335'], ['E05.599.395.397'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['G05.365.590']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Estrogenic and anti-estrogenic activities of Cassia tora phenolic constituents. | Through an estrogenic activity bioassay-guided fractionation of the 70% ethanolic extract of Cassia tora seeds two new phenolic triglucosides, torachrysone 8-O-[beta-D-glucopyranosyl(1-->3)-O-beta-D-glucopyranosyl(1-->6)-O-beta-D-glucopyranoside] (1) and toralactone 9-O-[beta-D-glucopyranosyl-(1-->3)-O-beta-D-glucopyra... | ['Cassia', 'Cell Line, Tumor', 'Estrogen Receptor alpha', 'Ethanol', 'Humans', 'Naphthols', 'Phenols', 'Phytoestrogens', 'Plant Extracts', 'Pyrones', 'Sesquiterpenes', 'Two-Hybrid System Techniques'] | 17,917,292 | [['B01.650.940.800.575.912.250.401.100'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.776.826.750.350.174'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.847.638.638', 'D04.615.638.638'], ['D02.455.426.559.389.657'], ['D27.505.696.399.472.277.540.500'], ['D20.215.784.500', 'D26.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fever alters osmosensitivity of hypothalamic-vasopressin system in the rat. | The osmosensitivity of peripheral vasopressin release was studied during healthy thermoregulation and endotoxin-induced fever. There was an increase in osmosensitivity following bolus injection of saline in febrile rats. These animals displayed a steeper slope in the linear relationship between plasma osmolality and pl... | ['Animals', 'Arginine Vasopressin', 'Blood Pressure', 'Blood Volume', 'Body Temperature Regulation', 'Fever', 'Hypothalamo-Hypophyseal System', 'Infusions, Intravenous', 'Male', 'Osmolar Concentration', 'Rats', 'Rats, Sprague-Dawley', 'Sodium Chloride', 'Urine'] | 8,402,384 | [['B01.050'], ['D06.472.699.631.692.781.100', 'D12.644.400.900.100', 'D12.644.456.925.100', 'D12.644.548.691.692.781.100', 'D12.776.631.650.937.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.188.130', 'G09.330.380.092'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['C23.888.119.344'], ['A06.688.357', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Complexation of bioreducible cationic polymers with gold nanoparticles for improving stability in serum and application on nonviral gene delivery. | Widespread applications of conventional polymeric gene carriers are greatly hampered by their inefficient transfection performance under serum-containing environment. Aiming to overcome this limitation, we propose a bioreducible polyethylenimine-gold nanocomplex system (SSPEI-Au NC), which can be prepared by a simple l... | ['Absorbable Implants', 'Cations', 'DNA', 'Gold', 'HEK293 Cells', 'Humans', 'MCF-7 Cells', 'Materials Testing', 'Metal Nanoparticles', 'Nanocapsules', 'Polymers', 'Serum', 'Transfection'] | 25,764,067 | [['E07.695.025'], ['D01.248.497.300'], ['D13.444.308'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.251.210.190.630'], ['E05.570'], ['J01.637.512.600.500'], ['D26.255.260.575', 'E02.319.300.380.575', 'J01.637.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Retroperitoneal tumours--a ten years retrospective study. | In a ten-year retrospective study (1985-95), 42 cases of retroperitoneal tumours were analysed. All cases were treated surgically. Among the relevant investigations CT scan and fine needle aspiration cytology were found to be most helpful to have a pre-operative idea regarding the best course of therapy. The highest in... | ['Adolescent', 'Adult', 'Age Distribution', 'Aged', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retroperitoneal Neoplasms', 'Retrospective Studies'] | 16,008,325 | [['M01.060.057'], ['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.033.731'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Probing DNA Translocations with Inplane Current Signals in a Graphene Nanoribbon with a Nanopore. | Many theoretical studies predict that DNA sequencing should be feasible by monitoring the transverse current through a graphene nanoribbon while a DNA molecule translocates through a nanopore in that ribbon. Such a readout would benefit from the special transport properties of graphene, provide ultimate spatial resolut... | ['DNA', 'Electric Conductivity', 'Electrochemical Techniques', 'Equipment Design', 'Graphite', 'Motion', 'Nanopores', 'Nanostructures', 'Nanotechnology', 'Sequence Analysis, DNA'] | 29,474,060 | [['D13.444.308'], ['G01.358.500.249.277'], ['E05.301'], ['E05.320'], ['D01.268.150.300', 'D01.578.300'], ['G01.482'], ['J01.637.512.650'], ['J01.637.512'], ['H01.603', 'J01.897.520.600'], ['E05.393.760.700']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
[Data from measuring air pathogens of inhabitants of refuse disposal sites in Cairo (1)]. | Atmospheric germ measurements were carried out and the germ spectrum determined in medical ambulances, bedrooms and livingrooms. | ['Air Microbiology', 'Bacteria', 'Colony Count, Microbial', 'Cross Infection', 'Egypt', 'Humans', 'Microbial Sensitivity Tests', 'Refuse Disposal'] | 2,583,508 | [['H01.158.273.540.274.110', 'N06.850.425.110'], ['B03'], ['E01.370.225.875.220', 'E05.200.875.220'], ['C01.248', 'C23.550.291.875.500'], ['Z01.058.266.317'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['N06.850.780.200.800.800.700', 'N06.850.860.510.... | ['Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Calcium balance in uremia: longitudinal study of long-term survivors. | Twelve male patients surviving uremia of 9-15 years duration were studied sequentially over a mean period of 9.2 years. Radiographs, bone biopsies, bone mineral mass (BMM) measured by photon absorptiometry, and total body calcium (TBC) determined by in vivo neutron activation analysis (NAA) were used. Pathologic fractu... | ['Adult', 'Aluminum', 'Bone and Bones', 'Calcinosis', 'Calcium', 'Chronic Kidney Disease-Mineral and Bone Disorder', 'Fractures, Spontaneous', 'Humans', 'Hyperparathyroidism, Secondary', 'Male', 'Middle Aged', 'Minerals', 'Neutron Activation Analysis', 'Time Factors', 'Uremia'] | 4,047,271 | [['M01.060.116'], ['D01.268.557.050', 'D01.552.547.050'], ['A02.835.232', 'A10.165.265'], ['C18.452.174.130'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['C05.116.198.816.750', 'C12.777.419.080', 'C13.351.968.419.795', 'C18.452.104.816.750', 'C18.452.174.845.750', 'C18.654.521.500.133.770.734.750', 'C19.64... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Characterization of Croatian Rape (Brassica | Rape (Brassica sp.) unifloral honey from Croatia was characterized by certain physicochemical parameters, micro- and macroelement content, and pollen spectrum, as determined in 21 honey samples. The Brassica sp. pollen type was predominant in the analyzed samples and ranged between 60 and 98%, with Trifolium spp., Robi... | ['Brassica', 'Chemical Phenomena', 'Croatia', 'Honey', 'Pollen'] | 28,573,965 | [['B01.650.940.800.575.912.250.157.200'], ['G02'], ['Z01.542.248.295'], ['G07.203.300.581', 'J02.500.581'], ['A18.024.249.500.249.500']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Modulation of gephyrin-glycine receptor affinity by multivalency. | Gephyrin is a major determinant for the accumulation and anchoring of glycine receptors (GlyRs) and the majority of ã-aminobutyric acid type A receptors (GABAARs) at postsynaptic sites. Here we explored the interaction of gephyrin with a dimeric form of a GlyR â-subunit receptor-derived peptide. A 2 ? crystal structure... | ['Binding Sites', 'Calorimetry', 'Carrier Proteins', 'Chromatography, Liquid', 'Dimerization', 'Ligands', 'Mass Spectrometry', 'Membrane Proteins', 'Receptors, Glycine'] | 25,137,389 | [['G02.111.570.120'], ['E05.196.131'], ['D12.776.157'], ['E05.196.181.400'], ['G02.206', 'G03.230'], ['D27.720.470.480'], ['E05.196.566'], ['D12.776.543'], ['D12.776.157.530.400.175.781', 'D12.776.157.530.400.400.100.200', 'D12.776.543.550.450.175.781', 'D12.776.543.550.450.500.100.200', 'D12.776.543.585.400.175.781', ... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ploidy of 36 stromal tumors of the gastrointestinal tract. A comparative study with flow cytometry and image analysis. | DNA ploidy was investigated by flow cytometry (FC) and image analysis (IA) in paraffin-embedded tissue sections from 36 stromal tumors of the gastrointestinal tract. The results of both techniques were correlated with pathologic features of the tumors and survival. Ten (27.8%) tumors were aneuploid by FC and IA. Most o... | ['Flow Cytometry', 'Gastrointestinal Neoplasms', 'Humans', 'Image Processing, Computer-Assisted', 'Ploidies'] | 7,710,619 | [['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['G05.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Autoimmunity as the consequence of a spontaneous mutation in Rasgrp1. | A mouse strain was identified with a recessive genetic lesion, which spontaneously developed a lymphoproliferative autoimmune syndrome exhibiting features of systemic lupus erythematosus. Positional mapping of the disease-associated locus revealed a lesion in Rasgrp1 that prevented the translation of the RasGRP1 protei... | ['Animals', 'Apoptosis', 'Autoimmune Diseases', 'Autoimmunity', 'B-Lymphocytes', 'CD4-Positive T-Lymphocytes', 'Cell Division', 'Cytokines', 'DNA-Binding Proteins', 'Guanine Nucleotide Exchange Factors', 'Immunologic Memory', 'Lupus Erythematosus, Systemic', 'Lymphocyte Activation', 'MAP Kinase Signaling System', 'Mice... | 12,932,358 | [['B01.050'], ['G04.146.954.035'], ['C20.111'], ['G12.450.192'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['G04.144.220', 'G04.161.750.500', ... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A new approach to autocalibrated dynamic parallel imaging based on the Karhunen-Loeve transform: KL-TSENSE and KL-TGRAPPA. | TSENSE and TGRAPPA are autocalibrated parallel imaging techniques that can improve the temporal resolution and/or spatial resolution in dynamic magnetic resonance imaging applications. In its original form, TSENSE uses temporal low-pass filtering of the undersampled frames to create the sensitivity map. TGRAPPA uses a ... | ['Artifacts', 'Calibration', 'Exercise Test', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Imaging, Cine', 'Motion', 'Myocardial Contraction', 'Phantoms, Imaging', 'Principal Component Analysis', 'Respiration', 'Sensitivity and Specificity', 'Thoracic Wall'] | 21,254,210 | [['E05.047'], ['E05.978.155'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500.510'], ['G01.482'], ['G09.330.580', 'G11.427.494.570'], ['E07.671'], ['E05.318.740.562'], ['G09.772.705'], ['E05.318.370.800', 'E05.318.74... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Do ethics committees need a legal framework? | The question "do ethics committees need a legal framework" may then raise fundamental discussion in the case of developing countries: will an ethical framework bring them a better capacity to assume their task? And what should this task be if we consider the particularities of clinical research conducted in developing ... | ['Biomedical Research', 'Cultural Diversity', 'Developing Countries', 'Ethics Committees, Research', 'Humans', 'International Cooperation', 'Multicenter Studies as Topic', 'United Nations', 'World Health Organization'] | 17,902,584 | [['H01.770.644.145'], ['I01.076.201.450.350', 'I01.880.853.100.450'], ['I01.615.500.300'], ['K01.752.566.479.147.750', 'N04.452.758.788.300.750', 'N05.350.268.750', 'N05.700.685.300.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.615.500'], ['E05.318.372.658', 'N05.715.360.330.643', 'N06.850.520.450.643']... | ['Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Hyporesponsiveness to inhibitory agents of alveolar macrophages and polymorphonuclear leukocytes primed by platelet activating factor. | In this study, it was presented that PAF and LTB4 exert a priming effect on PMNs to promote their superoxide anion production. PMNs preincubated with PAF of normal controls or PMNs from asthmatic patients are activated and their responsiveness to inhibitory stimuli such as antiallergic drugs and corticosteroid are atte... | ['Adult', 'Aged', 'Asthma', 'Bronchial Hyperreactivity', 'Cells, Cultured', 'Dexamethasone', 'Female', 'Humans', 'Leukotriene B4', 'Lymphocyte Activation', 'Macrophage Activation', 'Macrophages, Alveolar', 'Male', 'Middle Aged', 'Neutrophils', 'Phthalazines', 'Platelet Activating Factor', 'Superoxides'] | 8,389,539 | [['M01.060.116'], ['M01.060.116.100'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['C08.127.210'], ['A11.251'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.251.355.255.100.450.411', 'D10.251.355.310.166.887.411', 'D23.469.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Vertical trauma: injuries to patients who fall and land on their feet. | We reviewed the patterns of injuries sustained by 12 consecutive fallers and jumpers in whom primary impact was onto the feet. The fall heights ranged from 20 to 100 ft. The 12 patients sustained 49 significant injuries. Skeletal injuries were most frequent and included 15 lower extremity fractures, four pelvic fractur... | ['Accidental Falls', 'Accidents', 'Adolescent', 'Adult', 'Aged', 'Child', 'Female', 'Humans', 'Male', 'Middle Aged', 'Multiple Trauma', 'Suicide, Attempted', 'Wounds and Injuries'] | 2,916,780 | [['N06.850.135.122'], ['N06.850.135'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C26.640'], ['F01.145.126.980.875.600', 'I01.880.735.856.600'], ['C26']] | ['Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Evaluation of Postharvest Washing on Removal of Silver Nanoparticles (AgNPs) from Spinach Leaves. | There is increasing use of silver nanoparticles (AgNPs) as pesticides for fruits and vegetables due to the particles' unique antimicrobial and insecticidal properties. However, residual AgNPs in harvested produce may transfer through the food chain and pose a potential risk to public health. The objective of this study... | ['Anti-Infective Agents', 'Food Contamination', 'Food Handling', 'Metal Nanoparticles', 'Plant Leaves', 'Silver', 'Spectrum Analysis, Raman', 'Spinacia oleracea'] | 27,548,506 | [['D27.505.954.122'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['J01.576.423.200'], ['J01.637.512.600.500'], ['A18.024.812'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.544.812'], ['E05.196.822.860', 'E05.196.867.890'], ['B01.650.940.800.575.912.250.200.800']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Spatial-temporal characteristics and driving factors of the human health impacts of five industrial aquatic toxic metals in China. | With the rapid advancement of industrialization without effective supervision, industrial aquatic toxic metal (TM) emissions pose threats to human health in China. Due to differences in socioeconomic development, the regional disparity of industrial aquatic TM emissions is obvious nationwide. In this study, the human h... | ['China', 'Environmental Health', 'Environmental Monitoring', 'Heavy Metal Poisoning', 'Humans', 'Industry', 'Mercury', 'Metals, Heavy', 'Water Pollutants'] | 32,300,920 | [['Z01.252.474.164'], ['H02.229'], ['N06.850.460.350.080', 'N06.850.780.375'], ['C25.723.522'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.576'], ['D01.268.556.504', 'D01.268.956.437', 'D01.552.544.504'], ['D01.268.556', 'D01.552.544'], ['D27.888.284.903']] | ['Geographicals [Z]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 |
Technical Note: Evaluation of the systematic accuracy of a frameless, multiple image modality guided, linear accelerator based stereotactic radiosurgery system. | PURPOSE: To evaluate the total systematic accuracy of a frameless, image guided stereotactic radiosurgery system.METHODS: The localization accuracy and intermodality difference was determined by delivering radiation to an end-to-end prototype phantom, in which the targets were localized using optical surface monitoring... | ['Calibration', 'Equipment Design', 'Particle Accelerators', 'Phantoms, Imaging', 'Radiometry', 'Radiosurgery', 'Radiotherapy, Image-Guided', 'Robotics'] | 27,147,363 | [['E05.978.155'], ['E05.320'], ['E07.710.680'], ['E07.671'], ['E05.799'], ['E02.815.530', 'E04.525.800.650', 'E05.873.500'], ['E02.815.768'], ['H01.671.293.643', 'J01.897.104.834', 'L01.224.050.375.630']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Catecholamine induced double tachycardia: case report in a child. | A six-year-old girl with syncope in association with atrial flutter-fibrillation and ventricular tachycardia produced by exercise or emotion is presented. The tachycardias could be reproduced by low-dose isoproterenol infusion and were blocked by high dose propranolol therapy. Catecholamine-induced tachyarrhythmias sho... | ['Atrial Fibrillation', 'Catecholamines', 'Child', 'Electrocardiography', 'Electrophysiology', 'Female', 'Humans', 'Physical Exertion', 'Propranolol', 'Stress, Psychological', 'Syncope', 'Tachycardia'] | 6,160,500 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
["Thermogradient" unit]. | An experimental device--Thermogradient--for studying the behaviour of small animals under various thermal conditions has been described. Constructive circuit of thermoplates and principal circuits of thermoregulator and test thermometer are given. The device provides using of various combinations of temperature gradien... | ['Animals', 'Behavior, Animal', 'Electronics', 'Physiology', 'Temperature', 'Thermometers'] | 6,850,008 | [['B01.050'], ['F01.145.113'], ['H01.671.293'], ['H01.158.782'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710'], ['E07.900']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Brain activation during manipulation of the myoelectric prosthetic hand: a functional magnetic resonance imaging study. | Neuroimaging data, particularly functional magnetic resonance imaging (fMRI) findings, have not been reported in users of the myoelectric or electromyographic (EMG) prosthetic hand. We developed a virtual EMG prosthetic hand system to eliminate mutual signal noise interference between fMRI imaging and the EMG prosthesi... | ['Action Potentials', 'Artificial Limbs', 'Biofeedback, Psychology', 'Cerebellum', 'Computer Graphics', 'Dominance, Cerebral', 'Electrodes', 'Electromyography', 'Electronic Data Processing', 'Functional Laterality', 'Hand', 'Hand Strength', 'Humans', 'Image Processing, Computer-Assisted', 'Imaging, Three-Dimensional', ... | 15,050,584 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['E07.695.050', 'E07.858.082.050', 'E07.858.442.050'], ['E02.190.525.123', 'F02.830.131', 'F04.754.137.301', 'F04.754.308.500'], ['A08.186.211.132.810.428.200'], ['L01.224.108', 'L01.296.110'], ['F02.830.297', 'G11.561.225'], ['E07.305.250'], ['E01.370.405.255', '... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Patterns of outcome in schizophrenia in Hong Kong. | A total of 153 schizophrenic subjects were included for outcome assessment in different aspects of their life functions. The same group of subjects was followed-up 1 year later to assess the consistency of their outcome pattern. A factor analysis on the outcome measures was conducted, and 5 independent factors were not... | ['Activities of Daily Living', 'Adolescent', 'Adult', 'Combined Modality Therapy', 'Cross-Cultural Comparison', 'Cross-Sectional Studies', 'Female', 'Follow-Up Studies', 'Hong Kong', 'Hospitalization', 'Humans', 'Male', 'Middle Aged', 'Psychiatric Status Rating Scales', 'Quality of Life', 'Rehabilitation, Vocational', ... | 1,746,286 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.057'], ['M01.060.116'], ['E02.186'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Experiences of partners of prostate cancer survivors: A qualitative study. | Prostate cancer, Australia's leading cancer, has treatment side effects that reduce the quality of life for both survivors and partners. Limited partner research exists. This study aimed to address this gap in the literature by gathering data directly from partners to obtain a deeper understanding of their experiences ... | ['Adaptation, Psychological', 'Aged', 'Aged, 80 and over', 'Australia', 'Cancer Survivors', 'Female', 'Focus Groups', 'Humans', 'Male', 'Middle Aged', 'Prostatic Neoplasms', 'Qualitative Research', 'Quality of Life', 'Sexual Partners'] | 28,506,193 | [['F01.058'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.639.100', 'Z01.678.100.373'], ['M01.860.350'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Structural changes and fluctuations of proteins. II. Analysis of the denaturation of globular proteins. | The statistical thermodynamic model of protein structure proposed in paper I is developed with special attention to the hydrophobic interaction. Calorimetric measurements of the thermal denaturation of five globular proteins, ribonuclease A, lysozyme, alpha-chymotrypsin, cytochrome c, and myoglobin, are quantitatively ... | ['Calorimetry, Differential Scanning', 'Chemical Phenomena', 'Chemistry', 'Globulins', 'Hot Temperature', 'Hydrogen-Ion Concentration', 'Mathematics', 'Models, Chemical', 'Protein Denaturation', 'Ribonucleases', 'Solubility', 'Solvents', 'Thermodynamics', 'Water'] | 15,668 | [['E05.196.131.310', 'E05.196.370.310'], ['G02'], ['H01.181'], ['D12.776.377'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G02.300'], ['H01.548'], ['E05.599.495'], ['G01.154.651.750.500', 'G02.111.688.750.500'], ['D08.811.27... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Evolution of Salmonella enterica virulence via point mutations in the fimbrial adhesin. | Whereas the majority of pathogenic Salmonella serovars are capable of infecting many different animal species, typically producing a self-limited gastroenteritis, serovars with narrow host-specificity exhibit increased virulence and their infections frequently result in fatal systemic diseases. In our study, a genetic ... | ['Adhesins, Bacterial', 'Amino Acid Sequence', 'Animals', 'Base Sequence', 'Biological Evolution', 'Gene Knockout Techniques', 'Humans', 'Macrophages', 'Mice', 'Mice, Inbred BALB C', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Phylogeny', 'Point Mutation', 'Salmonella Infections', 'Salmonella enterica', '... | 22,685,400 | [['D12.776.097.120.050', 'D12.776.543.100.050', 'D23.050.161.050'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045', 'G16.075'], ['E05.393.335.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.329.372', 'A11.627.482', 'A11.733.39... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A combined molecular dynamic simulation and urea 14N NMR relaxation study of the urea-lysozyme system. | Urea in the lysozyme solvation shell has been studied by utilizing a combination of urea 14N, water 17O NMR relaxation experiments and a molecular dynamics simulation of the urea-lysozyme system. Samples with lysozyme in the native fold in water as well as in 3M urea have been studied, as well as denatured lysozyme in ... | ['Animals', 'Anti-Infective Agents', 'Chickens', 'Models, Molecular', 'Molecular Dynamics Simulation', 'Muramidase', 'Nuclear Magnetic Resonance, Biomolecular', 'Protein Conformation', 'Protein Denaturation', 'Protein Folding', 'Urea', 'Water'] | 20,061,179 | [['B01.050'], ['D27.505.954.122'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.599.595'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D08.811.277.450.642'], ['E05.196.867.519.550'], ['G02.111.570.820.709'], ['G01.154.651.750.500', 'G02.111.688.750.500'], ['G01.154.651', 'G02.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease. | Type IX collagen is a nonfibrillar collagen composed of three gene products, alpha 1(IX), alpha 2(IX), and alpha 3(IX). Type IX molecules are localized on the surface of type II-containing fibrils and consist of two arms, a long arm that is crosslinked to type II collagen and a short arm that projects into the perifibr... | ['Animals', 'Cell Line', 'Collagen', 'Homozygote', 'Mice', 'Mutation', 'Osteoarthritis', 'Stem Cells'] | 8,197,187 | [['B01.050'], ['A11.251.210'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G05.380.554'], ['B01.050.150.900.649.313.992.635.505.500'], ['G05.365.590'], ['C05.550.114.606', 'C05.799.613'], ['A11.872']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A comparison of working postures of parcel sorters using three different working methods. | The postures of the trunk of eight parcel sorters were measured continuously under three different working conditions, during whole shifts. The working methods used were two different sorting tables and a hydraulic lifting platform on which the carts were to be placed. The question posed by the PTT-Post occupational he... | ['Adult', 'Ergometry', 'Humans', 'Male', 'Movement', 'Netherlands', 'Physical Exertion', 'Postal Service', 'Posture', 'Work'] | 8,119,262 | [['M01.060.116'], ['E05.333'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410'], ['Z01.542.651'], ['G11.427.683'], ['I01.451.617'], ['G11.427.695'], ['I03.946']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Dense deconvolution net: Multi path fusion and dense deconvolution for high resolution skin lesion segmentation. | BACKGROUND: Dermoscopy imaging has been a routine examination approach for skin lesion diagnosis. Accurate segmentation is the first step for automatic dermoscopy image assessment.OBJECTIVE: The main challenges for skin lesion segmentation are numerous variations in viewpoint and scale of skin lesion region.METHODS: To... | ['Dermoscopy', 'Diagnosis, Differential', 'Humans', 'Image Processing, Computer-Assisted', 'Neural Networks, Computer', 'Nevus', 'Skin Neoplasms'] | 29,758,959 | [['E01.370.350.515.277.250', 'E05.595.185.250'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['G17.485', 'L01.224.050.375.605'], ['C04.557.665.560'], ['C04.588.805', 'C17.800.882']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Employee competence and performance-based assessment: A college of American pathologists Q-probes study of larboratory personnel in 522 institutions. | OBJECTIVE: To survey employee competence assessment practices in departments of pathology and laboratory medicine and provide suggestions for improvement.DESIGN: A 3-part study consisting of a questionnaire about current competence assessment practices, an evaluation of compliance with stated competence assessment prac... | ['Educational Measurement', 'Employee Performance Appraisal', 'Hospitals, Teaching', 'Humans', 'Laboratories, Hospital', 'Medical Laboratory Personnel', 'Pathology, Clinical', 'Professional Competence', 'Quality Assurance, Health Care', 'Societies, Medical', 'Specimen Handling', 'Surveys and Questionnaires', 'United St... | 10,656,726 | [['I02.399'], ['N04.452.677.370'], ['N02.278.020.300', 'N02.278.421.639'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.278.216.500.968.420', 'N02.278.487.410', 'N04.452.442.452.422.420'], ['M01.526.485.510', 'M01.526.502.500', 'N02.360.510'], ['H02.403.650.500'], ['I02.399.630'], ['N04.761.700', 'N05.700'], ... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
An early circulating factor in severe sepsis modulates apoptosis of monocytes and lymphocytes. | We hypothesized that a factor may circulate in serum early during sepsis, modulating apoptosis of monocytes and lymphocytes. Serum was collected from 20 healthy volunteers and from 48 patients with severe sepsis/shock within 12 h from signs of the first failing organ. PBMCs were isolated from 20 healthy volunteers and ... | ['Aged', 'Apoptosis', 'CD4-Positive T-Lymphocytes', 'Caspase 3', 'Cell Extracts', 'Cell Separation', 'Demography', 'Female', 'Humans', 'Immunologic Factors', 'Lipopolysaccharide Receptors', 'Male', 'Monocytes', 'Sepsis', 'fas Receptor'] | 21,030,664 | [['M01.060.116.100'], ['G04.146.954.035'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['D20.777.162'], ['E01.370.225.500.3... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Amorphous cellulose feed supplement alters the broiler caecal microbiome. | The grains that form the basis of most commercial chicken diets are rich in cellulose, an unbranched â-1,4-linked D-glucopyranose polymer, used as a structural molecule in plants. Although it is a predominant polysaccharide in cereal hulls, it is considered an inert non-fermentable fiber. The aim of the current study w... | ['Animal Feed', 'Animals', 'Cecum', 'Cellulose', 'Chickens', 'Diet', 'Dietary Supplements', 'Gastrointestinal Microbiome', 'Male'] | 31,065,709 | [['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['A03.556.124.526.209', 'A03.556.249.249.209'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G07.203.650.240'], ['G07.203.300.456', 'J02.500.456'], ['G... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Comparative effects of fosinopril and irbesartan on hematopoiesis in essential hypertensives. | OBJECTIVE: To compare the response of erythropoiesis to an angiotensin receptor blocker, irbesartan with an angiotensin conversing enzyme inhibitor, fosinopril, in essential hypertensive patients with normal renal function.DESIGN AND METHODS: Thirty patients were randomized to receive either irbesartan (150 mg once dai... | ['Aged', 'Angiotensin II Type 1 Receptor Blockers', 'Angiotensin-Converting Enzyme Inhibitors', 'Biphenyl Compounds', 'Erythrocyte Count', 'Female', 'Follow-Up Studies', 'Fosinopril', 'Hematopoiesis', 'Hemoglobins', 'Humans', 'Hypertension', 'Irbesartan', 'Male', 'Middle Aged', 'Tetrazoles', 'Time Factors'] | 15,462,108 | [['M01.060.116.100'], ['D27.505.519.162.500'], ['D27.505.519.389.745.085'], ['D02.455.426.559.389.185'], ['E01.370.225.500.195.107.330', 'E01.370.225.625.107.330', 'E05.200.500.195.107.330', 'E05.200.625.107.330', 'E05.242.195.107.330', 'G04.140.107.330', 'G09.188.105.330'], ['E05.318.372.500.750.249', 'N05.715.360.330... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Limited-host-range plasmid of Agrobacterium tumefaciens: molecular and genetic analyses of transferred DNA. | A tumor-inducing (Ti) plasmid from a strain of Agrobacterium tumefaciens that induces tumors on only a limited range of plants was characterized and compared with the Ti plasmids from strains that induce tumors on a wide range of plants. Whereas all wide-host-range Ti plasmids characterized to date contain closely link... | ['DNA, Bacterial', 'Gene Expression Regulation', 'Genes, Bacterial', 'Mutation', 'Plant Tumors', 'Plasmids', 'Rhizobium', 'Species Specificity'] | 4,008,445 | [['D13.444.308.212'], ['G05.308'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.365.590'], ['G15.610.700'], ['G05.360.600'], ['B03.440.400.425.700.800', 'B03.585.900', 'B03.660.050.662.670'], ['G16.824']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Liquid chromatography-mass spectrometry with on-line solid-phase extraction by a restricted-access C18 precolumn for direct plasma and urine injection. | In this paper, the on-line coupling of solid-phase extraction, based on a restricted-access support with liquid chromatography-mass spectrometry (LC-MS), for the analysis of biological samples is described. The system was tested with cortisol and prednisolone for plasma analysis and arachidonic acid for urine analysis.... | ['Arachidonic Acid', 'Blood Chemical Analysis', 'Chromatography, Liquid', 'Fludrocortisone', 'Hydrocortisone', 'Mass Spectrometry', 'Online Systems', 'Prednisolone', 'Urinalysis'] | 9,098,977 | [['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['E01.370.225.124.100', 'E05.200.124.100'], ['E05.196.181.400'], ['D04.210.500.745.745.654.600.500'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['E05.196.566'], ['L01.313.500.750.300.742'], ['D04.210.500.745.432.769.79... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of ischemia and reperfusion on sarcoplasmic reticulum calcium uptake. | To investigate the mechanism underlying postischemic cardiac dysfunction (myocardial stunning), contractility and adenine nucleotide metabolism were studied in three groups of isolated perfused rabbit hearts (control, ischemic, and reperfused), whereas Ca2+ uptake by the sarcoplasmic reticulum (SR) was measured in homo... | ['Adenine Nucleotides', 'Animals', 'Calcium', 'In Vitro Techniques', 'Myocardial Contraction', 'Myocardial Ischemia', 'Myocardial Reperfusion', 'Myocardium', 'Rabbits', 'Sarcoplasmic Reticulum'] | 1,394,874 | [['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.481'], ['G09.330.580', 'G11.427.494.570'], ['C14.280.647', 'C14.907.585'], ['E04.100.700.600', 'E05.680.730.600'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['B01.050.15... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Assessing the relationship between functional impairment/recovery and depression severity: a pooled analysis. | The objective of this study was to explore the relationship between assessments of functional impairment, emotional well-being, and depression symptoms. Data were pooled from 3530 outpatients with major depressive disorder enrolled in 10 desvenlafaxine clinical trials. The primary outcome measures included (a) the 17-i... | ['Adult', 'Antidepressive Agents', 'Clinical Trials as Topic', 'Cyclohexanols', 'Depressive Disorder, Major', 'Desvenlafaxine Succinate', 'Disability Evaluation', 'Emotions', 'Evidence-Based Medicine', 'Female', 'Humans', 'Linear Models', 'Logistic Models', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Psychiatr... | 21,971,533 | [['M01.060.116'], ['D27.505.954.427.700.122'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D02.033.415.510.500', 'D02.455.426.392.368.367.318', 'D10.289.510.500'], ['F03.600.300.375'], ['D02.033.415.510.500.303', 'D02.455.426.392.368.367.318.500', 'D02.455.426.559.389.657.265', 'D10... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Taste-mixture suppression: functional dissection of cellular and paracellular origins. | 1. Chorda tympani (CT) nerve responses were recorded during simultaneous current and voltage clamping of the lingual receptive-field epithelium to examine the role of field potential in taste mixture suppression between sodium gluconate (NaG) and potassium gluconate (KG). 2. Under zero current-clamp conditions, CT resp... | ['Animals', 'Chorda Tympani Nerve', 'Electrophysiology', 'Evoked Potentials', 'Female', 'Gluconates', 'In Vitro Techniques', 'Kinetics', 'Patch-Clamp Techniques', 'Rats', 'Rats, Sprague-Dawley', 'Signal Transduction', 'Taste', 'Taste Buds', 'Tight Junctions', 'Tongue'] | 8,734,608 | [['B01.050'], ['A08.800.800.120.250.120'], ['H01.158.344.528', 'H01.158.782.236'], ['G07.265.216.500', 'G11.561.200.500'], ['D02.241.081.844.322', 'D02.241.511.902.322', 'D09.811.308'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['E05.200.500.905', 'E05.242.800'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.05... | ['Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Computed tomography in hepatic trauma. | Twenty-five patients with hepatic injury from blunt upper abdominal trauma were examined by computed tomography (CT). The spectrum of CT findings was recorded, and the size of the hepatic laceration and the associated hemoperitoneum were correlated with the mode of therapy used in each case (operative vs. nonoperative)... | ['Hematoma', 'Hemoperitoneum', 'Humans', 'Liver', 'Liver Diseases', 'Tomography, X-Ray Computed', 'Wounds, Nonpenetrating'] | 6,603,125 | [['C23.550.414.838'], ['C06.844.400', 'C23.550.414.888'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['C06.552'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810'], ['C26.974']] | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Platinum-promoted Ga/Al₂O₃ as highly active, selective, and stable catalyst for the dehydrogenation of propane. | A novel catalyst material for the selective dehydrogenation of propane is presented. The catalyst consists of 1000 ppm Pt, 3 wt% Ga, and 0.25 wt% K supported on alumina. We observed a synergy between Ga and Pt, resulting in a highly active and stable catalyst. Additionally, we propose a bifunctional active phase, in wh... | ['Aluminum Oxide', 'Catalysis', 'Gallium', 'Hydrogenation', 'Platinum', 'Propane'] | 24,989,975 | [['D01.056.050', 'D01.650.550.050'], ['G02.130'], ['D01.268.556.289', 'D01.552.544.289'], ['G02.111.380', 'G02.607.324', 'G03.409'], ['D01.268.556.690', 'D01.268.956.734', 'D01.552.544.690'], ['D02.455.326.146.800']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Penetrating chest injuries caused by swordfish sword used as a weapon. | We report 5 cases of penetrating chest wounds caused by weapons made from swordfish swords, involving breakage of the sword that later appeared as a thoracic foreign body. The patients had been assaulted 2 days to 17 years earlier. Three of them had a chronic infected wound, one had a penetrating thoracic wound with he... | ['Adolescent', 'Adult', 'Hemopneumothorax', 'Humans', 'Male', 'Thoracic Injuries', 'Thoracotomy', 'Tomography, X-Ray Computed', 'Weapons', 'Wounds, Stab', 'Young Adult'] | 28,185,476 | [['M01.060.057'], ['M01.060.116'], ['C08.528.338', 'C23.550.414.904.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.891'], ['E04.928.760'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.370.350.825.810.810'], ['J01.637.870'], ['C26.986.95... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
A Golgi and electron microscope study of the ventral septum in the reptile, Podarcis hisp?nica. | The ventral septum of the reptile Podarcis hisp?nica has been studied using cytoarchitectonical and Golgi methods as well as electron microscopy techniques. The ventral septum is located in the medial wall of the telencephalon, just ventral to the dorsal septum. 2 different cell masses or nuclei can be easily appreciat... | ['Animals', 'Lizards', 'Microscopy, Electron', 'Neurons', 'Telencephalon'] | 3,400,895 | [['B01.050'], ['B01.050.150.900.833.393'], ['E01.370.350.515.402', 'E05.595.402'], ['A08.675', 'A11.671'], ['A08.186.211.200.885']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Treatment of recurrent tension headache: a meta-analytic review. | The primary aim of this study was to investigate which treatment, patient, and study characteristics are related to treatment outcome in tension headache. Literature on the subject was obtained by searching for articles published in English through CD-rom Compact Cambridge and PSYCHLIT (1970/1993) on the subjects of he... | ['Humans', 'Recurrence', 'Tension-Type Headache'] | 7,833,575 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.291.937'], ['C10.228.140.546.399.875']] | ['Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Wireless ECG transfer and centralized system of ECG analysis and storage. Experience with easy ECG usage in the Russian Cardiological Research Center]. | Methods of wire and wireless ECG remote registration anda centralized system of ECG reception, analysis and storage are outlined in the context of setting up computer case history. Qualitative assessment of an algorithm of computer syndromal diagnosis used in the Easy ECG system is presented. The system comprises an EC... | ['Algorithms', 'Diagnosis, Computer-Assisted', 'Electrocardiography', 'Equipment Design', 'Humans', 'Russia', 'Software', 'Wireless Technology'] | 22,774,492 | [['G17.035', 'L01.224.050'], ['E01.158', 'L01.313.500.750.100.158'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.122.500', 'Z01.542.248.775'], ['L01.224.900'], ['L01.178.847.950']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Separate effects of triploidy, parentage and genomic diversity upon feeding behaviour, metabolic efficiency and net energy balance in the Pacific oyster Crassostrea gigas. | Triploid oysters were induced using cytochalasin B upon retention of either the first (meiosis I triploids) or the second (meiosis II triploids) polar body in embryos from a single cohort derived from mixed parentage. Allozyme and microsatellite assays enabled the confirmation of both parentage and triploidy status in ... | ['Animals', 'Animals, Laboratory', 'Biopsy', 'Breeding', 'Cytochalasin B', 'Energy Metabolism', 'Feeding Behavior', 'Genetic Variation', 'Genotype', 'Heterozygote', 'Image Processing, Computer-Assisted', 'Meiosis', 'Metabolism', 'Microsatellite Repeats', 'Ostreidae', 'Oxygen Consumption', 'Ploidies', 'Quantitative Trai... | 11,204,974 | [['B01.050'], ['B01.050.050.199'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E05.820.150', 'G05.090'], ['D03.633.100.473.231.370', 'D23.946.587.370.370'], ['G03.295'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.3... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The role of IL-10 in promoting disease progression in leishmaniasis. | To determine the role of IL-10 in cutaneous leishmaniasis, we examined lesion development following Leishmania major infection of genetically susceptible BALB/c mice lacking IL-10. Whereas normal BALB/c mice developed progressive nonhealing lesions with numerous parasites within them, IL-10(-/-) BALB/c mice controlled ... | ['Adjuvants, Immunologic', 'Animals', 'Cell-Free System', 'Disease Progression', 'Immunoglobulin G', 'Interferon-gamma', 'Interleukin-10', 'Interleukin-12', 'Leishmania major', 'Leishmaniasis, Cutaneous', 'Lipopolysaccharides', 'Macrophage Activation', 'Macrophages', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C3H', '... | 11,145,695 | [['D27.505.696.477.067'], ['B01.050'], ['A11.284.835.168'], ['C23.550.291.656'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.44... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gramicidin S biosynthesis operon containing the structural genes grsA and grsB has an open reading frame encoding a protein homologous to fatty acid thioesterases. | The DNA sequence of about 5.9 kilobase pairs (kbp) of the gramicidin S biosynthesis operon (grs) was determined. Three open reading frames were identified; the corresponding genes, called grsT, grsA, and grsB, were found to be organized in one transcriptional unit, not two as previously reported (M. Krause and M. A. Ma... | ['Amino Acid Sequence', 'Bacillus', 'Bacterial Proteins', 'Base Sequence', 'Genes, Bacterial', 'Gramicidin', 'Molecular Sequence Data', 'Molecular Weight', 'Operon', 'Palmitoyl-CoA Hydrolase', 'Promoter Regions, Genetic', 'Restriction Mapping', 'Single-Strand Specific DNA and RNA Endonucleases', 'Thiolester Hydrolases'... | 2,477,357 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B03.300.390.400.158.218', 'B03.353.500.100.218', 'B03.510.100.100.218', 'B03.510.415.400.158.218', 'B03.510.460.410.158.218'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.34... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Assessing Incidence and Risk Factors of Cervical Spine Injury in Blunt Trauma Patients Using the National Trauma Data Bank. | Despite the potentially devastating impact of missed cervical spine injuries (CI), there continues to be a large disparity in how institutions attempt to make the diagnosis. To better streamline the approach among institutions, understanding incidence and risk factors across the country is paramount. We evaluated the i... | ['Adult', 'Cervical Vertebrae', 'Female', 'Humans', 'Incidence', 'Injury Severity Score', 'Male', 'Middle Aged', 'Registries', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors', 'Spinal Injuries', 'Survival Rate', 'Trauma Centers', 'United States', 'Wounds, Nonpenetrating'] | 26,350,665 | [['M01.060.116'], ['A02.835.232.834.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E05.318.308.940.968.875.500', 'E05.944.600', 'N04.452.859.564.800.500', 'N05.715.360.300.715.500.800.400'], ['M0... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Biohistorical approaches to "race" in the United States: Biological distances among African Americans, European Americans, and their ancestors. | Folk taxonomies of race are the categorizations used by people in their everyday judgments concerning the persons around them. As cultural traditions, folk taxonomies may shape gene flow so that it is unequal among groups sharing geography. The history of the United States is one of disparate people being brought toget... | ['African Americans', 'Anthropology, Physical', 'Continental Population Groups', 'Culture', 'European Continental Ancestry Group', 'History, 17th Century', 'History, 18th Century', 'History, 19th Century', 'History, 20th Century', 'Humans', 'Models, Theoretical', 'Odontometry', 'Principal Component Analysis', 'United S... | 19,226,643 | [['M01.686.508.100.100', 'M01.686.754.100'], ['I01.076.368'], ['M01.686.508'], ['I01.076.201.450', 'I01.880.853.100'], ['M01.686.508.400'], ['K01.400.504.750'], ['K01.400.504.875'], ['K01.400.504.937'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['E01.370.600.024.650', 'E05.041.6... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Suppression of Aâ toxicity by puromycin-sensitive aminopeptidase is independent of its proteolytic activity. | The accumulation of â-amyloid (Aâ) peptide in the brain is one of the pathological hallmarks of Alzheimer's disease and is thought to be of primary aetiological significance. In an unbiased genetic screen, we identified puromycin-sensitive aminopeptidase (PSA) as a potent suppressor of Aâ toxicity in a Drosophila model... | ['Alzheimer Disease', 'Aminopeptidases', 'Amyloid beta-Peptides', 'Animals', 'Animals, Genetically Modified', 'Autophagy', 'Blotting, Western', 'Brain', 'Drosophila melanogaster', 'Enzyme-Linked Immunosorbent Assay', 'Flow Cytometry', 'Fluorescent Antibody Technique', 'Humans', 'Immunoenzyme Techniques', 'Neuroblastoma... | 23,911,349 | [['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['D08.811.277.656.350.100'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['G04.011'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
TRPC1 expression and distribution in rat hearts. | Transient receptor potential canonical (TRPC) proteins have been identified as a family of plasma membrane calcium-permeable channels. TRPC proteins can be activated by various stimuli and act as cellular sensors in mammals. Stretch-activated ion channels (SACs) have been proposed to underlie cardiac mechano-electric f... | ['Animals', 'Endothelial Cells', 'Fibroblasts', 'Fluorescent Antibody Technique', 'Heart Atria', 'Heart Ventricles', 'Immunohistochemistry', 'Myocardium', 'Myocytes, Cardiac', 'Myocytes, Smooth Muscle', 'Purkinje Cells', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'TRPC Cation Channels', 'Tissue Distribution'] | 22,073,358 | [['B01.050'], ['A11.436.275'], ['A11.329.228'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['A07.541.358'], ['A07.541.560'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', ... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Economic crises, behavioral changes and hospitalization due to affective disorders in Brazil between 2003 and 2017: a nationwide cross-sectional study. | Our aim was to analyze hospitalization due to affective disorders in Brazil from 2003 to 2017 and the possible association with economic indicators during crises. We used data on hospitalizations due to affective disorders within the Brazilian National Health System, obtained from DATASUS; data on health-related behavi... | ['Brazil', 'Cross-Sectional Studies', 'Databases, Factual', 'Health Behavior', 'Hospitalization', 'Humans', 'Mood Disorders'] | 32,294,714 | [['Z01.107.757.176'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['F01.145.488'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03.600']] | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Maduramicin inactivation of Akt impairs autophagic flux leading to accumulated autophagosomes-dependent apoptosis in skeletal myoblast cells. | It has been clinically documented that maduramicin (Mad), a polyether ionophore antibiotic widely used in the control of coccidiosis in poultry worldwide, can elicit skeletal muscle degeneration, heart failure, and even death in animals and humans, if improperly used. Here, we show that Mad induced apoptosis dose-depen... | ['Animals', 'Apoptosis', 'Autophagic Cell Death', 'Autophagosomes', 'Cell Line', 'Lactones', 'Mice', 'Microtubule-Associated Proteins', 'Myoblasts, Skeletal', 'Proto-Oncogene Proteins c-akt'] | 31,325,628 | [['B01.050'], ['G04.146.954.035'], ['G04.011.500', 'G04.146.954.053'], ['A11.284.430.214.190.875.190.700.500'], ['A11.251.210'], ['D02.540'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.220.600.450', 'D12.776.631.560'], ['A11.872.620.500'], ['D08.811.913.696.620.682.700.755', 'D12.776.476.565', 'D12.776.624.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hereditary haemorrhagic telangiectasia, an Australian cohort: clinical and investigative features. | AIM: The present study aims to describe the phenotypic features of patients with hereditary haemorrhagic telangiectasia (HHT) seen at Royal Melbourne Hospital, Victoria, Australia, and to customise a protocol for surveillance of patients with HHT.METHODS: This is a retrospective study in a tertiary referral hospital of... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Australia', 'Cohort Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Retrospective Studies', 'Telangiectasia, Hereditary Hemorrhagic', 'Victoria', 'Young Adult'] | 24,750,312 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.639.100', 'Z01.678.100.373'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750',... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Tyrosinase activity and the expression of the agouti gene in the mouse. | Tyrosinase activity at the time of phaeomelanin synthesis in neonatal mice is lower in agouti than in black skin and hair bulb tissue, and this depressed activity is associated with a reduction in the electrophoretically distinct de novo form of the enzyme. Direct chemical measurements of sulphydryl compounds show elev... | ['Animals', 'Catechol Oxidase', 'Genes', 'Hair Color', 'Isoenzymes', 'Melanocytes', 'Mice', 'Mice, Inbred C3H', 'Mice, Inbred CBA', 'Mice, Mutant Strains', 'Monophenol Monooxygenase', 'Mutation', 'Skin Pigmentation'] | 3,119,767 | [['B01.050'], ['D08.811.682.690.708.125'], ['G05.360.340.024.340'], ['G13.500', 'G16.690.490'], ['D08.811.348', 'D12.776.800.300'], ['A11.409.750', 'A11.436.613'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.388', 'B01.050.150.900.649.313.992.635.505.500.400.388'], ['B01.050.050.199.520.520.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
D-mannose-specific Immunoglobulin M in Grass Puffer (Takifugu niphobles), a Nonhost Fish of a Monogenean Ectoparasite Heterobothrium okamotoi, Can Act as a Trigger for its Parasitism. | Heterobothrium okamotoi, a monogenean gill parasite, exhibits high host specificity for the tiger puffer, Takifugu rubripes, and it has been experimentally verified that the parasite cannot colonize either closely related species such as the grass puffer Takifugu niphobles or distantly related fish such as the red seab... | ['Amino Acid Sequence', 'Animals', 'Blotting, Western', 'Cilia', 'Cloning, Molecular', 'DNA, Complementary', 'Ectoparasitic Infestations', 'Electrophoresis, Polyacrylamide Gel', 'Fish Diseases', 'Gene Expression', 'Gills', 'Host Specificity', 'Hydrogen-Ion Concentration', 'Immunoglobulin M', 'Mannose', 'Mucous Membrane... | 32,294,759 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.284.180.165'], ['E05.393.220'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['C01.610.858.211'], ['E05.196.401.402', 'E0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Multiple evanescent white dot syndrome. A diagnostic dilemma]. | PURPOSE/METHOD: We present a patient with multiple evanescent white-dot syndrome (MEWDS). On presentation the patient was not initially diagnosed. The diagnosis was established eighteen months later by the clinical, angiographic and electrophysiologic features. We emphasize the difficulties to establish the diagnosis, ... | ['Adult', 'Chorioretinitis', 'Diagnosis, Differential', 'Female', 'Fluorescein Angiography', 'Fundus Oculi', 'Glucocorticoids', 'Humans', 'Immunosuppressive Agents', 'Syndrome', 'Treatment Outcome', 'Visual Acuity'] | 12,955,626 | [['M01.060.116'], ['C11.768.773.348', 'C11.941.160.478.400', 'C11.941.879.780.900.300.318'], ['E01.171'], ['E01.370.370.050.350', 'E01.370.380.250'], ['A09.371.729.313'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['C23.550.288.500'], ['E01.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Topographo-anatomical substantiation of the choice of a rational approach to the terminal region of the thoracic duct]. | With the aim to state the dependence between the projection of the place where the thoracic duct flows into and the superior part of its arc with the position of its external reference marks in order to choose a rational approach to the terminal part of the thoracic duct, an investigation on 50 embalmed human corpses h... | ['Adult', 'Aged', 'Drainage', 'Humans', 'Middle Aged', 'Thoracic Duct'] | 7,165,521 | [['M01.060.116'], ['M01.060.116.100'], ['E02.309', 'E04.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A15.382.520.301.750']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cross-cultural adaptation of the Malay version of the parent-proxy Health-Related Quality of Life Measure for Children with Epilepsy (CHEQOL-25) in Malaysia. | PURPOSE: We aimed to cross-culturally adapt the parent-proxy Health-Related Quality of Life Measure for Children with Epilepsy (CHEQOL-25) into Malay and to determine its validity and reliability among parents of children with epilepsy in Malaysia.METHODS: The English version of the parent-proxy CHEQOL-25 was translate... | ['Adolescent', 'Child', 'Cross-Cultural Comparison', 'Epilepsy', 'Female', 'Humans', 'Malaysia', 'Male', 'Parents', 'Pilot Projects', 'Proxy', 'Psychometrics', 'Quality of Life', 'Reproducibility of Results', 'Translations'] | 25,819,800 | [['M01.060.057'], ['M01.060.406'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.145.487'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], [... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Humanities [K]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
The Test for Severe Impairment: an instrument for the assessment of patients with severe cognitive dysfunction. | OBJECTIVE: To develop a reliable and valid test of cognitive function suitable for patients with severe cognitive impairment.DESIGN: Administration of a test; test-retest reliability; comparison to traditional test.SETTING: Chronic long-term-care facility.PATIENTS OR OTHER PARTICIPANTS: The participants were 40 elderly... | ['Aged', 'Aged, 80 and over', 'Cognition Disorders', 'Female', 'Humans', 'Male', 'Mental Status Schedule', 'Neuropsychological Tests', 'Reproducibility of Results'] | 1,634,695 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F03.615.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513.603.500', 'F04.711.513.653.574'], ['F04.711.513'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The cAMP transduction cascade mediates olfactory reception in Drosophila melanogaster. | Two main second messenger systems depending on IP3 and cAMP have been related to olfaction in vertebrates as well as invertebrates. In Drosophila melanogaster, the availability of mutations affecting one or the other pathway (rdgB and norpA or rut and dnc, respectively) allowed showing of abnormal olfactory behavior ph... | ['Animals', 'Animals, Genetically Modified', 'Choice Behavior', 'Crosses, Genetic', 'Cyclic AMP', 'DNA-Binding Proteins', 'Drosophila melanogaster', 'Female', 'Genes, Reporter', 'Hybridization, Genetic', 'Male', 'Saccharomyces cerevisiae Proteins', 'Signal Transduction', 'Transcription Factors'] | 15,082,937 | [['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['F02.463.785.373.346'], ['E05.393.281'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D12.776.260'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G05.360.340.024.340.435'], ['E05.820.150.390', 'G05.090.39... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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