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Radically Healing Black Lives: A Love Note to Justice. | This chapter describes how present conditions in Black communities have fostered the development of new modes of youth leadership that focus on hope, love, and joy, and are ultimately restorative and redemptive. | ['Adolescent', 'Adult', 'African Americans', 'Hope', 'Humans', 'Leadership', 'Love', 'Social Justice', 'Young Adult'] | 26,895,167 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['F01.470.572'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.609'], ['F01.470.734'], ['I01.880.604.473.700', 'K01.752.566.479.830.750', 'N03.706.437.700', 'N05.350.958.750'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The subcellular organization of cortactin in hippocampus. | Spines may undergo rapid, activity-dependent changes in shape and size, reflecting reorganization of the actin cytoskeleton. This remodeling is implicated in development and also in the late phase of long-term potentiation. However, the cellular mechanisms that convert activity into morphological change remain poorly u... | ['Actins', 'Animals', 'Cortactin', 'Dendritic Spines', 'Hippocampus', 'Immunohistochemistry', 'Male', 'Microfilament Proteins', 'Microscopy, Confocal', 'Microscopy, Electron', 'Neurons', 'Rats', 'Rats, Sprague-Dawley'] | 15,548,644 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['D05.750.078.730.281', 'D12.644.360.024.280', 'D12.776.157.057.014', 'D12.776.220.525.281', 'D12.776.476.024.311', 'D12.776.744.390'], ['A08.675.256.200', 'A11.284.180.225.169', 'A11.671.240.169'], ['A08.186.211.180.405', 'A08.186.211... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Motion deficit of the thumb in CMC joint arthritis. | PURPOSE: Idiopathic osteoarthritis (OA) of the thumb carpometacarpal (CMC) joint is a common disabling disease that often causes pain and motion loss. The aims of this study were to characterize the multidimensional motion capability of the thumb CMC joint in a group with severe CMC OA and to compare it with a control ... | ['Analysis of Variance', 'Carpometacarpal Joints', 'Case-Control Studies', 'Female', 'Hand Strength', 'Humans', 'Male', 'Middle Aged', 'Osteoarthritis', 'Pain Measurement', 'Range of Motion, Articular', 'Reference Values', 'Risk Assessment', 'Severity of Illness Index', 'Thumb'] | 20,807,622 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['A02.835.583.405.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.600.425.500', 'G11.427.560.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.550.114.606', 'C05.799.613']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Rapid diagnosis of beta-thalassemia mutations in Chinese by naturally and amplified created restriction sites. | We developed a rapid and simple method to diagnose the molecular defects of beta-thalassemia in Chinese patients. This method involves the selective amplification of a DNA fragment from human beta globin gene with specific oligonucleotide primers, followed by digestion with restriction enzymes that recognize artificial... | ['Base Sequence', 'Codon', 'DNA', 'Deoxyribonuclease EcoRI', 'Deoxyribonucleases, Type II Site-Specific', 'Globins', 'Humans', 'Molecular Sequence Data', 'Mutation', 'Polymerase Chain Reaction', 'Restriction Mapping', 'Taiwan', 'beta-Thalassemia'] | 1,391,961 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['D13.444.308'], ['D08.811.150.280.260.300', 'D08.811.277.352.335.350.300.260.250', 'D08.811.277.352.355.325.300.260.250'], ['D08.811.150.280.260', 'D08.811.277.352.335.350.300.260', 'D... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Chronic inflammatory arthritis of the ankle/hindfoot/midfoot complex in children with extreme obesity. | BACKGROUND: Childhood obesity is an increasing public health concern, but little is known about how obesity contributes to chronic arthritis.OBJECTIVE: The objective of this study was to identify and characterize children and adolescents who present with isolated arthritis of the ankle/hindfoot/midfoot complex and prof... | ['Adolescent', 'Age Factors', 'Ankle Joint', 'Antibodies, Antinuclear', 'Arthritis, Juvenile', 'Body Mass Index', 'Child', 'Cohort Studies', 'Female', 'Foot Joints', 'Humans', 'Male', 'Obesity', 'Prevalence', 'Retrospective Studies', 'Risk Factors', 'Severity of Illness Index', 'Sex Factors'] | 25,160,015 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['A02.835.583.378.062'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['C05.550.114.122', 'C05.799.056', 'C17.300.775.049', 'C20.111.198'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.... | ['Named Groups [M]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Transient neonatal diabetes mellitus in half sisters. A sequel. | This is a sequel to a previous report of two half sisters with transient neonatal diabetes mellitus. In 1970, the same syndrome developed in a third half sibling, a boy, born of the same father by his third wife. It followed essentially the same neonatal clinical course as that of his two half sisters. The firstborn si... | ['Adolescent', 'Diabetes Mellitus', 'Female', 'Humans', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Male'] | 7,091,092 | [['M01.060.057'], ['C18.452.394.750', 'C19.246'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A Pr?fer-Sequence Based Algorithm for Calculating the Size of Ideal Randomly Branched Polymers. | Branched polymers can be represented as tree graphs. A one-to-one correspondence exists between a tree graph comprised of N labeled vertices and a sequence of N - 2 integers, known as the Pr?fer sequence. Permutations of this sequence yield sequences corresponding to tree graphs with the same vertex-degree distribution... | ['Algorithms', 'Models, Chemical', 'Polymers'] | 27,104,292 | [['G17.035', 'L01.224.050'], ['E05.599.495'], ['D05.750', 'D25.720', 'J01.637.051.720']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Screening of virulence traits in Legionella pneumophila and analysis of the host susceptibility to infection by using the Dictyostelium host model system. | The social soil amoeba Dictyostelium discoideum has been established as a host model for several human pathogens including Legionella pneumophila. The complete genome sequence, the genetic tractability, and the phagocytic characteristics of Dictyostelium generate many opportunities for the study of host-pathogen intera... | ['Animals', 'Dictyostelium', 'Host-Pathogen Interactions', 'Legionella pneumophila', 'Lysosomes', 'Microbiological Techniques', 'Models, Biological', 'Mutation', 'Phagosomes', 'Virulence'] | 19,089,374 | [['B01.050'], ['B01.046.550.200.300'], ['G06.462', 'G16.527.200'], ['B03.440.400.425.450.450.500', 'B03.660.250.460.460.580'], ['A11.284.430.214.190.875.190.550'], ['E01.370.225.875', 'E05.200.875'], ['E05.599.395'], ['G05.365.590'], ['A11.284.430.214.190.875.190.700'], ['G06.930']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Purification of interstitial cells of Cajal by fluorescence-activated cell sorting. | Interstitial cells of Cajal (ICC) in the gastrointestinal tract generate and propagate slow waves and mediate neuromuscular neurotransmission. Although damages to ICC have been described in several gastrointestinal motor disorders, analysis of their gene expression in health and disease has been problematic because of ... | ['Animals', 'Antigens, CD', 'Antigens, Differentiation, Myelomonocytic', 'Biomarkers', 'Cell Separation', 'Flow Cytometry', 'Fluorescent Antibody Technique', 'Gastrointestinal Tract', 'Macrophages', 'Magnetics', 'Mice', 'Mice, Inbred BALB C', 'Muscle, Smooth', 'Proto-Oncogene Proteins c-kit', 'RNA, Messenger', 'Reverse... | 14,534,083 | [['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.900', 'D23.101.100.900'], ['D23.101'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Kinetic properties, nutrient-dependent regulation and energy coupling of amino-acid transport systems in Penicillium cyclopium. | In submerged grown hyphae of Penicillium cyclopium the activities of seven transport systems could be distinguished which share in the uptake of L-arginine, L-glutamic acid, L-phenylalanine and L-leucine. They include the specific systems a (accepting L-arginine and L-lysine), b (L-phenylalanine, L-tyrosine), c (L-glut... | ['Adenosine Triphosphate', 'Amino Acid Transport Systems', 'Amino Acids', 'Ammonia', 'Arginine', 'Biological Transport', 'Biological Transport, Active', 'Carbon', 'Carrier Proteins', 'Cycloheximide', 'Energy Metabolism', 'Glutamates', 'Glutamic Acid', 'Hydrogen-Ion Concentration', 'Kinetics', 'Leucine', 'Membrane Trans... | 2,563,328 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D12.776.157.530.200', 'D12.776.543.585.200'], ['D12.125'], ['D01.362.075', 'D01.625.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['G03.143'], ['G03.143.310'], ['D01.268.150'], ['D12.776.157'], ['D03.383.621.808.240'],... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of combined carotid sinus and aortic depressor nerve denervations in neonatal rat pups. | Denervation of the major peripheral chemo- and barosensory organs of neonatal mammals is known to produce age-dependent effects on mortality and on respiratory and cardiovascular functions. In the current series of experiments, these phenomena were more fully characterized in the young rat. 8- to 9-day-old rats showed ... | ['Age Factors', 'Animals', 'Animals, Newborn', 'Aorta', 'Body Temperature', 'Carotid Sinus', 'Denervation', 'Electrocardiography', 'Female', 'Heart Rate', 'Male', 'Rats', 'Rats, Wistar', 'Respiration', 'Time Factors', 'Weight Gain'] | 9,129,794 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['B01.050.050.282'], ['A07.015.114.056'], ['E01.370.600.875.374', 'G07.110'], ['A07.015.114.186.456'], ['E04.525.210'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150... | ['Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Labral Repair Versus Biceps Tenodesis for Primary Surgical Management of Type II Superior Labrum Anterior to Posterior Tears: A Systematic Review. | PURPOSE: To examine the outcomes of SLAP repair versus biceps tenodesis (BT) for the index treatment of isolated type II SLAP tears.METHODS: A search of PubMed, MEDLINE, and EMBASE was performed in April 2018 for English-language studies that presented outcomes data on patients with isolated type II SLAP tears treated ... | ['Arm', 'Arthroscopy', 'Case-Control Studies', 'Cohort Studies', 'Humans', 'Muscle, Skeletal', 'Prospective Studies', 'Reoperation', 'Retrospective Studies', 'Shoulder Injuries', 'Shoulder Joint', 'Tenodesis'] | 31,053,457 | [['A01.378.800.075'], ['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.567', 'A10.690.552.500... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Volatile monoterpenes in black currant (Ribes nigrum L.) juice: effects of heating and enzymatic treatment by beta-glucosidase. | Changes of terpenes in black currant juice induced by the action of heat were investigated in the present study. Limonene, alpha-terpinene, linalool, alpha-terpineol, 4-terpineol, and menthol added to either black currant juice or a model system were thermally treated at 90 degrees C for 30 min. Similar heat-induced de... | ['Beverages', 'Fruit', 'Hot Temperature', 'Hydrolysis', 'Monoterpenes', 'Ribes', 'Volatilization', 'beta-Glucosidase'] | 16,536,610 | [['G07.203.100', 'J02.200'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G02.380'], ['D02.455.849.575'], ['B01.650.940.800.575.912.250.859.937.311.500'], ['G01.645.750', 'G02... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Glycine-directed peptide amidation: presence in rat brain of two enzymes that convert p-Glu-His-Pro-Gly-OH into p-Glu-His-Pro-NH2 (thyrotropin-releasing hormone). | To study the possibility of glycine-directed amidation in rat brain, we synthesized the substrate p-Glu-His-Pro-Gly-OH. Adult and neonatal rat brain and adult rat pituitary were sonicated, frozen and thawed, and fractionated by gel permeation chromatography, and fractions from each tissue were assayed for enzymatic act... | ['Aging', 'Animals', 'Animals, Newborn', 'Brain', 'Glycine', 'Kinetics', 'Mass Spectrometry', 'Pituitary Gland', 'Protein Processing, Post-Translational', 'Pyrrolidonecarboxylic Acid', 'Rats', 'Rats, Inbred Strains', 'Substrate Specificity', 'Thyrotropin-Releasing Hormone'] | 6,427,768 | [['G07.345.124'], ['B01.050'], ['B01.050.050.282'], ['A08.186.211'], ['D12.125.481'], ['G01.374.661', 'G02.111.490'], ['E05.196.566'], ['A06.300.747', 'A06.688.357.750', 'A08.186.211.180.497.352.435.500', 'A08.186.211.200.317.357.352.435.500', 'A08.713.357.750'], ['G02.111.660.871.790.600', 'G02.111.691.600', 'G03.734.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Time course images of cellular injury and recovery in murine brain with high-resolution GRIN lens system. | Time course, in vivo imaging of brain cells is crucial to fully understand the progression of secondary cellular damage and recovery in murine models of injury. We have combined high-resolution gradient index lens technology with a model of diffuse axonal injury in rodents to enable repeated visualization of fine featu... | ['Animals', 'Axons', 'Brain', 'Brain Injuries, Traumatic', 'Brain Ischemia', 'Carotid Arteries', 'Coronary Occlusion', 'Female', 'Fluorescent Dyes', 'Male', 'Mice', 'Mice, Transgenic', 'Microglia', 'Microscopy, Fluorescence, Multiphoton', 'Myelin Sheath', 'Neuroimaging', 'Regeneration', 'White Matter'] | 31,138,885 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['A08.186.211'], ['C10.228.140.199.444', 'C10.900.300.087.235', 'C26.915.300.200.194'], ['C10.228.140.300.150', 'C14.907.253.092'], ['A07.015.114.186'], ['C14.280.647.250.272', 'C14.907.585.250.272'], ['D27.720.233.348', 'D27.720.47... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gas vesicle genes identified in Bacillus megaterium and functional expression in Escherichia coli. | Gas vesicles are intracellular, protein-coated, and hollow organelles found in cyanobacteria and halophilic archaea. They are permeable to ambient gases by diffusion and provide buoyancy, enabling cells to move upwards in liquid to access oxygen and/or light. In halobacteria, gas vesicle production is encoded in a 9-kb... | ['Amino Acid Sequence', 'Bacillus megaterium', 'Bacillus subtilis', 'Bacterial Proteins', 'Cloning, Molecular', 'Escherichia coli', 'Gases', 'Gene Expression', 'Gene Transfer Techniques', 'Genes, Bacterial', 'Molecular Sequence Data', 'Multigene Family', 'Organelles', 'Sequence Analysis, DNA', 'Sequence Homology, Amino... | 9,573,198 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B03.300.390.400.158.218.500', 'B03.353.500.100.218.500', 'B03.510.100.100.218.500', 'B03.510.415.400.158.218.500', 'B03.510.460.410.158.218.500'], ['B03.300.390.400.158.218.725', 'B03.353.500.100.218.725', 'B03.510.100.100.218.725', 'B03.510.415.400.158.218.725', 'B03.510.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The sharing of injecting equipment among drug users attending prescribing clinics and those using needle-exchanges. | Three groups of injecting drug-users were defined in terms of their experience of methadone treatment: treatment for periods longer than 6 months, treatment for shorter periods, and no treatment. Methadone treatment and the use of needle exchanges were related in subsequent analysis to the sharing of injecting equipmen... | ['Adolescent', 'Adult', 'Female', 'HIV Infections', 'Health Behavior', 'Humans', 'Male', 'Methadone', 'Needles', 'Opioid-Related Disorders', 'Patient Education as Topic', 'Substance Abuse, Intravenous'] | 2,021,704 | [['M01.060.057'], ['M01.060.116'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.522.675'], ['E07.612'], ['C25.775.643.500', 'F03.900.647.500'], ['I02.233.332.500', 'N02.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Binding of ATP to eukaryotic initiation factor 2. Differential modulation of mRNA-binding activity and GTP-dependent binding of methionyl-tRNAMetf. | Eukaryotic initiation factor 2 (eIF-2) is shown to bind ATP with high affinity. Binding of ATP to eIF-2 induces loss of the ability to form a ternary complex with Met-tRNAf and GTP, while still allowing, and even stimulating, the binding of mRNA. Ternary complex formation between eIF-2, GTP, and Met-tRNAf is inhibited ... | ['Adenosine Diphosphate', 'Adenosine Triphosphate', 'Adenylyl Imidodiphosphate', 'Animals', 'Binding Sites', 'Binding, Competitive', 'Deoxyadenine Nucleotides', 'Eukaryotic Initiation Factor-2', 'Guanosine Triphosphate', 'Guanylyl Imidodiphosphate', 'Kinetics', 'Macromolecular Substances', 'Penicillium chrysogenum', 'P... | 2,111,815 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D03.633.100.759.646.138.236.050', 'D13.695.667.138.236.050', 'D13.695.827.068.236.050'], ['B01.050'], ['G02.111.570.120'], ['E05.196.080', 'G02.111.084', 'G02.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Medical informatics: past, present, future. | OBJECTIVE: To reflect about medical informatics as a discipline. To suggest significant future research directions with the purpose of stimulating further discussion.METHODS: Exploring and discussing important developments in medical informatics from the past and in the present by way of examples. Reflecting on the rol... | ['Delivery of Health Care', 'History, 20th Century', 'History, 21st Century', 'Medical Informatics', 'Quality of Health Care', 'Societies, Scientific'] | 20,615,752 | [['N04.590.374', 'N05.300'], ['K01.400.504.968'], ['K01.400.504.984'], ['L01.313.500'], ['N04.761', 'N05.715'], ['N03.540.828.838']] | ['Health Care [N]', 'Humanities [K]', 'Information Science [L]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Set-up errors and planning margins in planar and CBCT image-guided radiotherapy using three different imaging systems: A clinical study for prostate and head-and-neck cancer. | PURPOSE: The purpose of this work is to compare the positioning accuracy achieved by three different imaging techniques and planar vs. CBCT imaging for two common IGRT indications.METHODS: A collective of prostate cancer and head-and-neck cancer patients treated at our institution during the year 2013 was retrospective... | ['Cone-Beam Computed Tomography', 'Head and Neck Neoplasms', 'Humans', 'Male', 'Phantoms, Imaging', 'Prostatic Neoplasms', 'Radionuclide Imaging', 'Radiotherapy Planning, Computer-Assisted', 'Radiotherapy Setup Errors', 'Radiotherapy, Image-Guided', 'Retrospective Studies'] | 26,476,789 | [['E01.370.350.700.810.810.490', 'E01.370.350.825.810.810.399'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.671'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E01.370.350.710', 'E01.370.384.730'], ['E02.950.825', 'L01.313.500.750.100.710.600.608'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Determinants of anticoagulant control in patients receiving warfarin. | 1 A hospital-based drug information system has been used to assess the time for which patients treated with warfarin were outside the range of Thrombotest values 5-10% and 5-15% and to examine possible contributory factors in situations where anticoagulation fell outside these ranges. 2 Anticoagulant control varied wit... | ['Adult', 'Aged', 'Aging', 'Blood Coagulation', 'Blood Coagulation Tests', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Female', 'Humans', 'Male', 'Middle Aged', 'Sex Factors', 'Time Factors', 'Warfarin'] | 901,698 | [['M01.060.116'], ['M01.060.116.100'], ['G07.345.124'], ['G09.188.390.150'], ['E01.370.225.625.115', 'E05.200.625.115'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N05.715.350.675', 'N06.850.490.875'], ['G01.910.857'], ['D03.383.6... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of antimalarial activity of Artemisia turanica extract with current drugs in vivo. | BACKGROUND & OBJECTIVES: The purpose of this study was to compare antimalarial activity of Artemisia turanica Krasch as Iranian flora with current antimalarial drugs against Plasmodium berghei in vivo in mice.METHODS: Air-dried aerial parts of Iranian flora A. turanica were collected from Khorasan, northeastern Iran, e... | ['Animals', 'Antimalarials', 'Artemisia', 'Disease Models, Animal', 'Iran', 'Malaria', 'Male', 'Mice', 'Plant Extracts', 'Plasmodium berghei', 'Treatment Outcome'] | 23,703,440 | [['B01.050'], ['D27.505.954.122.250.100.085'], ['B01.650.940.800.575.912.250.100.100'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['Z01.252.245.500.350'], ['C01.610.752.530', 'C01.920.875'], ['B01.050.150.900.649.313.992.635.505.500'], ['D20.215.784.500', 'D26.667'], ['B01.043.075.380.611.461'], ['E01.789.800', 'N... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Side effects of verapamil in infants. | Two infants with supraventricular tachycardia were given intravenous verapamil and subsequently suffered life threatening bradycardia and hypotension. As there were no predisposing factors, direct drug action is implicated and other reports of the adverse effects of verapamil are noted. Supraventricular tachycardia in ... | ['Bradycardia', 'Female', 'Humans', 'Hypotension', 'Infant', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Male', 'Tachycardia', 'Verapamil'] | 6,859,944 | [['C14.280.067.319', 'C23.550.073.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.514'], ['M01.060.703'], ['M01.060.703.520'], ['C16.614'], ['C14.280.067.845', 'C14.280.123.875', 'C23.550.073.845'], ['D02.092.471.683.953']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Creatine monohydrate and glucose supplementation to slow- and fast-growing chickens changes the postmortem pH in pectoralis major. | The energy status of the chicken at slaughter has a large impact on the development of pH postmortem and thus on color and water-holding capacity (WHC). Supplementation of creatine monohydrate and glucose (CMH+GLU) may increase the creatine content in the muscles before slaughter, thereby delaying the formation of lact... | ['Animals', 'Body Weight', 'Chickens', 'Color', 'Creatine', 'Dietary Supplements', 'Drinking', 'Eating', 'Female', 'Food Technology', 'Glucose', 'Hydrogen-Ion Concentration', 'Muscle, Skeletal', 'Postmortem Changes', 'Temperature', 'Water'] | 16,776,473 | [['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G01.590.540.199'], ['D02.078.370.280', 'D12.125.373'], ['G07.203.300.456', 'J02.500.456'], ['G07.203.650.283.249', 'G10.261... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Effects of different methods of purification on aggregation of scrapie infectivity. | High levels of scrapie infectivity were found in detergent-insoluble residues of hamster brain purified by either repeated pelleting in 10% NaCl or by separation in Nycodenz gradients. Titres determined by the method of incubation interval assay were 100-fold higher than titres measured by endpoint dilution assay. The ... | ['Animals', 'Brain', 'Cell Fractionation', 'Cell Membrane', 'Cricetinae', 'Prions', 'Ribonuclease, Pancreatic', 'Scrapie', 'Urea'] | 3,100,716 | [['B01.050'], ['A08.186.211'], ['E05.242.251'], ['A11.284.149'], ['B01.050.150.900.649.313.992.635.075.250'], ['D12.776.785'], ['D08.811.277.352.355.350.715', 'D08.811.277.352.700.350.715'], ['C01.207.800.717', 'C10.228.228.800.717', 'C10.574.843.850', 'C22.836.799'], ['D02.065.950']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Human red cell esterase D polymorphism in Denmark, its use in paternity cases and the description of a new phenotype. | Red cell esterase D (EsD) phenotypes were determined in a Danish population sample of 3,116 unrelated adults by starch-gel electrophoresis. A new phenotype was discovered, which appeared to be determined by the EsD1 allele and a new allele EsDCph. The gene frequencies observed were EsD1 = 0.9007, EsD2 = 0.0992, EsDCph ... | ['Adult', 'Alleles', 'Blood Protein Electrophoresis', 'Carboxylesterase', 'Carboxylic Ester Hydrolases', 'Child', 'Denmark', 'Erythrocytes', 'Female', 'Gene Frequency', 'Humans', 'Male', 'Paternity', 'Phenotype', 'Polymorphism, Genetic'] | 6,469,261 | [['M01.060.116'], ['G05.360.340.024.340.030'], ['E01.370.225.124.100.110', 'E05.196.401.076', 'E05.200.124.100.110', 'E05.301.300.049'], ['D08.811.277.352.100.100'], ['D08.811.277.352.100'], ['M01.060.406'], ['Z01.542.816.124'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['G05.330'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Anatomy [A]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Orbiviruses: A North American Perspective. | Orbiviruses are members of the Reoviridae family and include bluetongue virus (BTV) and epizootic hemorrhagic disease virus (EHDV). These viruses are the cause of significant regional disease outbreaks among livestock and wildlife in the United States, some of which have been characterized by significant morbidity and ... | ['Animals', 'Animals, Wild', 'Arthropod Vectors', 'Bluetongue', 'Bluetongue virus', 'Disease Reservoirs', 'Hemorrhagic Disease Virus, Epizootic', 'Humans', 'Livestock', 'North America', 'Orbivirus', 'Reoviridae Infections', 'Sheep', 'Viral Vaccines'] | 26,086,554 | [['B01.050'], ['B01.050.050.300'], ['N06.850.335.188.100', 'N06.850.520.203.375.100'], ['C01.920.500.125', 'C01.925.081.125', 'C01.925.782.791.315', 'C22.836.120'], ['B04.820.223.719.550.100'], ['N06.850.520.203.250'], ['B04.820.223.719.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.050.116.500']... | ['Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Vaccination with autologous tumour antigen-pulsed dendritic cells in advanced gynaecological malignancies: clinical and immunological evaluation of a phase I trial. | Dendritic cell (DC)-based therapy has proven to be effective in patients with malignant lymphoma, melanoma, and renal and prostate carcinoma. In this phase I clinical trial, we have shown that patients with advanced gynaecological malignancies can be effectively vaccinated with DC pulsed with keyhole limpet haemocyanin... | ['Adult', 'Antigen Presentation', 'Cancer Vaccines', 'Carcinoma', 'Combined Modality Therapy', 'Dendritic Cells', 'Drug Eruptions', 'Female', 'Hemocyanins', 'Humans', 'Hypersensitivity, Delayed', 'Immunocompetence', 'Immunologic Memory', 'Interferon-gamma', 'Lymphocyte Activation', 'Middle Aged', 'Ovarian Neoplasms', '... | 11,845,259 | [['M01.060.116'], ['G12.119', 'G12.450.050.400.070'], ['D20.215.894.200'], ['C04.557.470.200'], ['E02.186'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['C17.800.174.600', 'C20.543.206.380', 'C25.100.468.380'], ['D12.776.093.375', 'D12.776.556.462', 'D23.767.482'], ['B01.050.150.900.649.313.9... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A Biosensor-CMOS Platform and Integrated Readout Circuit in 0.18-ìm CMOS Technology for Cancer Biomarker Detection. | This paper presents a biosensor-CMOS platform for measuring the capacitive coupling of biorecognition elements. The biosensor is designed, fabricated, and tested for the detection and quantification of a protein that reveals the presence of early-stage cancer. For the first time, the spermidine/spermine N1 acetyltransf... | ['Biomarkers, Tumor', 'Biosensing Techniques', 'Electric Capacitance', 'Equipment Design', 'Humans', 'Neoplasms', 'Pilot Projects', 'Semiconductors'] | 28,832,523 | [['D23.101.140'], ['E05.601.043'], ['G01.358.500.249.270'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E07.305.625']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The Infants' Dermatitis Quality of Life Index. | BACKGROUND: The impact on quality of life (QOL) caused by atopic dermatitis (AD) has been quantified in children and adults using established QOL measures. However, these are not suitable for use in infants under the age of 4 years, when AD usually develops.OBJECTIVES: To validate a new parent-generated QOL questionnai... | ['Child, Preschool', 'Dermatitis, Atopic', 'Family Health', 'Female', 'Health Status Indicators', 'Humans', 'Infant', 'Infant Behavior', 'Male', 'Quality of Life', 'Reproducibility of Results', 'Severity of Illness Index', 'Surveys and Questionnaires', 'Treatment Outcome'] | 11,167,690 | [['M01.060.406.448'], ['C16.320.850.210', 'C17.800.174.193', 'C17.800.815.193', 'C17.800.827.210', 'C20.543.480.343'], ['N01.400.300'], ['E05.318.308.980.438.475', 'N05.715.360.300.800.438.375', 'N06.850.520.308.980.438.475'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.145.179.500'], ['I01.... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Characteristics of particulate constituents and gas precursors during the episode and non-episode periods. | UNLABELLED: Size-segregated distribution of ambient particulate matter (PM) was determined using a micro-orifice uniform deposition impactor (MOUDI) and a nano-MOUDI in southern Taiwan. Eleven water-soluble ionic species including six anions (NO3-, SO4(2-), Cl-, F-, NO2-, Br-) and five cations (NH4+, Na+, K+, Ca2+, Mg2... | ['Acids', 'Anions', 'Cations', 'Gases', 'Metals', 'Particulate Matter', 'Quaternary Ammonium Compounds'] | 23,447,862 | [['D01.029'], ['D01.248.497.158'], ['D01.248.497.300'], ['D01.362'], ['D01.552'], ['D20.633'], ['D01.625.062.500', 'D02.092.877', 'D02.675.276']] | ['Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulation of fatty acid biosynthesis as a possible mechanism for the mitoinhibitory effect of fumonisin B1 in primary rat hepatocytes. | The mitoinhibitory effect of fumonisin B1 (FB1) on the mitogenic response of epidermal growth factor (EGF) was investigated in primary hepatocyte cultures with respect to the alterations in the omega6 fatty acid metabolic pathway. Fatty acid analyses of hepatocytes showed that EGF treatment resulted in a significant de... | ['Alprostadil', 'Animals', 'Arachidonic Acid', 'Carboxylic Acids', 'Carcinogens, Environmental', 'Cell Death', 'Cell Division', 'Cells, Cultured', 'Dinoprostone', 'Epidermal Growth Factor', 'Fatty Acids', 'Fumonisins', 'Ibuprofen', 'Linoleic Acid', 'Liver', 'Mycotoxins', 'Rats'] | 10,574,646 | [['D10.251.355.255.550.250.100', 'D10.251.355.325.050', 'D23.469.050.175.725.250.100'], ['B01.050'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['D02.241'], ['D27.888.569.100.125'], ['G04.146'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['D10.251.355.255.550.250... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biocompatibility evaluation of laser-induced AAm and HEMA grafted EPR. Part 1: In-vitro study. | Samples based on ethylene-propylene rubber (EPR) have been surface grafted with acrylamide (AAm) and 2-hydroxyethyl methacrylate (HEMA) using CO2-pulsed laser as a stimulation source. Scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDXA) and attenuated total reflectance infrared (ATR-IR) spectra w... | ['Absorptiometry, Photon', 'Acrylamide', 'Acrylamides', 'Alkenes', 'Animals', 'Cell Adhesion', 'Ethylenes', 'Fractals', 'Lasers', 'Macrophages, Alveolar', 'Materials Testing', 'Methacrylates', 'Mice', 'Microscopy, Electron, Scanning', 'Rubber', 'Spectrophotometry, Infrared'] | 10,184,316 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['D02.065.122.015', 'D02.241.081.069.094.015'], ['D02.065.122', 'D02.241.081.069.094'], ['D02.455.326.271'], ['B01.050'], ['G04.022'], ['D02.455.326.271.367'], ['E05.599.125', 'G17.290'], ['E07.632.490', 'E07.710.520'], ['A11.329.372.600', 'A11.627.482.600', 'A11.733.397... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Aerobic fitness and cardiorespiratory function of pediatric cancer survivors]. | INTRODUCTION: Overall, more than 80% of children diagnosed with cancer will survive their immediate disease. This growing group of childhood cancer survivors is at an increased risk for several chronic diseases and increased mortality. Physical activity is a well-known and powerful means to reduce such complications, y... | ['Adolescent', 'Case-Control Studies', 'Child', 'Exercise Test', 'Heart Function Tests', 'Humans', 'Male', 'Neoplasms', 'Oxygen Consumption', 'Physical Fitness', 'Respiratory Function Tests', 'Respiratory Mechanics', 'Survivors'] | 22,741,209 | [['M01.060.057'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['E01.370.370.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['G03.680'], ['G11.427.685', 'I03.450.642.845.054.800', 'N01.400... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A protocol for wide awake local anaesthetic no tourniquet (WALANT) hand surgery in the context of the coronavirus disease 2019 (COVID-19) pandemic. | There are new and unique challenges to emergency surgery service provision posed by the Coronavirus disease 2019 global pandemic. It is in the best interests of patients for care providers to streamline services where possible to maximise the number of cases that can be performed by limited surgical and anaesthetic tea... | ['Anesthesia, Local', 'Anesthetics, Local', 'Betacoronavirus', 'COVID-19', 'Clinical Protocols', 'Coronavirus Infections', 'Hand', 'Humans', 'Infection Control', 'Orthopedic Procedures', 'Pandemics', 'Patient Selection', 'Personal Protective Equipment', 'Pneumonia, Viral', 'SARS-CoV-2', 'Tourniquets'] | 32,631,702 | [['E03.155.086.231'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['E02.183', 'N05.715.360.33... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Effects of hypercapnia with and without acidosis on hypoxic pulmonary vasoconstriction. | Acute respiratory disorders and permissive hypercapnic strategy may lead to alveolar hypoxia and hypercapnic acidosis. However, the effects of hypercapnia with or without acidosis on hypoxic pulmonary vasoconstriction (HPV) and oxygen diffusion capacity of the lung are controversial. We investigated the effects of hype... | ['Acidosis, Respiratory', 'Animals', 'Capillary Permeability', 'Endothelium, Vascular', 'Hydrogen-Ion Concentration', 'Hypercapnia', 'Hypoxia', 'In Vitro Techniques', 'Lung', 'Male', 'Metalloporphyrins', 'Nitric Oxide', 'Nitroarginine', 'Partial Pressure', 'Pulmonary Ventilation', 'Rabbits', 'Vasoconstriction'] | 19,717,554 | [['C08.618.846.093', 'C18.452.076.176.310'], ['B01.050'], ['G03.143.330', 'G09.330.165'], ['A07.015.700.500', 'A10.272.491.355'], ['G02.300'], ['C23.888.852.544'], ['C23.888.852.079'], ['E05.481'], ['A04.411'], ['D02.257.250', 'D03.383.129.578.840.500.640', 'D03.633.400.909.500.640', 'D04.345.783.500.640', 'D23.767.727... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Athletes' perceptions of National Collegiate Athletic Association-mandated sickle cell trait screening: insight for academic institutions and college health professionals. | OBJECTIVE: The study objective was to explore athletes' perspectives of National Collegiate Athletic Association (NCAA)-mandated sickle cell trait (SCT)-screening policy by examining race- and gender-related differences in athletes' perceptions regarding risk of having SCT and concern about loss of playing time.PARTICI... | ['Academies and Institutes', 'Athletes', 'Attitude of Health Personnel', 'Cross-Sectional Studies', 'Female', 'Humans', 'Logistic Models', 'Male', 'Mass Screening', 'Multivariate Analysis', 'Perception', 'Risk Factors', 'Sickle Cell Trait', 'Southeastern United States', 'Students', 'Surveys and Questionnaires', 'Univer... | 24,628,029 | [['N03.540.052'], ['M01.072'], ['F01.100.050', 'N05.300.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.... | ['Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Implementation of the biological passport: the experience of the International Cycling Union. | The concept of the biological passport is to evaluate, on an individual and longitudinal basis, the effects of doping substances and prohibited methods--blood doping and gene doping--on the body. Indirect biological markers can be measured and used to establish an individual's biological profile, when variations in an ... | ['Athletes', 'Doping in Sports', 'Humans', 'International Agencies', 'Performance-Enhancing Substances', 'Substance Abuse Detection'] | 21,204,287 | [['M01.072'], ['I01.880.735.265'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.540.514'], ['D27.505.696.620'], ['E05.885', 'N06.850.780.500.765']] | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Maternal exposure to fine particulate matter from a large coal mine fire is associated with gestational diabetes mellitus: A prospective cohort study. | BACKGROUND: In 2014, the Hazelwood coal mine fire was an unprecedented event that resulted in a six-week period of poor air quality in the Latrobe Valley in regional Australia. We aimed to determine whether maternal exposure to fine particulate matter in coal mine fire smoke was associated with selected obstetric compl... | ['Air Pollutants', 'Air Pollution', 'Australia', 'Coal', 'Diabetes, Gestational', 'Female', 'Humans', 'Maternal Exposure', 'Particulate Matter', 'Pregnancy', 'Prospective Studies'] | 31,831,154 | [['D27.888.284.101'], ['N06.850.460.100'], ['Z01.639.100', 'Z01.678.100.373'], ['D20.345.108', 'N06.230.132.258.108'], ['C13.703.170', 'C18.452.394.750.448', 'C19.246.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.460.350.145'], ['D20.633'], ['G08.686.784.769'], ['E05.318.372.500.750.625', 'N05.715.3... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Predictability of retroperitoneal lymph node metastasis by using clinicopathologic variables in surgically staged endometrial cancer. | The purpose of this study was to predict lymphatic involvement in endometrial cancer using clinicopathologic variables of patients treated with surgical staging. Overall, 461 patients treated with an initial surgical staging procedure including complete pelvic-para-aortic lymphadenectomy were included. The mean number ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Endometrial Neoplasms', 'Female', 'Humans', 'Lymphatic Metastasis', 'Middle Aged', 'Models, Theoretical', 'Neoplasm Staging', 'Predictive Value of Tests', 'Prognosis', 'Retroperitoneal Space'] | 16,803,527 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.945.418.948.585', 'C13.351.500.852.762.200', 'C13.351.937.418.875.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['E05.599'], ['E01.789.625'], ['E05.318.370.800.650', 'N05.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
PrEP on Twitter: Information, Barriers, and Stigma. | On May 14, 2014 the Centers for Disease Control and Prevention (CDC) endorsed the drug Truvada as an HIV preventative, called pre-exposure prophylaxis (PrEP). PrEP has been shown to dramatically reduce the risk of HIV infection, but its rate of adoption has been slow, and discourse surrounding it has been marked by sti... | ['Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination', 'HIV Infections', 'Health Knowledge, Attitudes, Practice', 'Health Services Accessibility', 'Humans', 'Pre-Exposure Prophylaxis', 'Social Media', 'Social Stigma', 'Treatment Refusal'] | 27,295,507 | [['D02.705.429.906.750', 'D03.383.742.680.245.500.600.750', 'D03.633.100.759.138.881.750', 'D13.570.230.329.525.500', 'D13.570.685.245.500.600.500', 'D26.310.423'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['F01.100.150.500', 'N05.300.15... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
The therapeutic efficacy of Bifidobacterium animalis subsp. lactis BB-12® | BACKGROUND: The pathogenesis of infant colic is poorly defined. Gut microbiota seems to be involved, supporting the potential therapeutic role of probiotics.AIMS: To assess the rate of infants with a reduction of ?50% of mean daily crying duration after 28 days of intervention with the probiotic Bifidobacterium animali... | ['Bifidobacterium animalis', 'Breast Feeding', 'Colic', 'Crying', 'Defecation', 'Double-Blind Method', 'Feces', 'Female', 'Gastrointestinal Microbiome', 'Humans', 'Infant', 'Infant Care', 'Male', 'Placebos', 'Probiotics', 'Treatment Outcome'] | 31,797,399 | [['B03.510.024.100.250', 'B03.510.460.400.400.049.100.250'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['C16.614.166'], ['F01.145.209.530.258', 'F01.525.200.310.300'], ['G10.261.165'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], [... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Induction of alkylator (melphalan) resistance in HL60 cells is accompanied by increased levels of topoisomerase II expression and function. | Human leukemic HL60 cells were selected for resistance to alkylating agents by stepwise exposure to increasing concentrations of L-phenylalanine mustard (melphalan). The resulting resistant cell line (R-HL60) was 4-fold resistant (melphalan IC50 value, 27.84 +/- 4.2 microM) to melphalan compared with parental HL60 cell... | ['Antineoplastic Agents, Alkylating', 'Cross-Linking Reagents', 'DNA Adducts', 'DNA Damage', 'DNA Topoisomerases, Type I', 'DNA Topoisomerases, Type II', 'DNA, Neoplasm', 'Doxorubicin', 'Enzyme Activation', 'Gene Expression', 'HL-60 Cells', 'Humans', 'Kinetics', 'Melphalan', 'Topoisomerase II Inhibitors'] | 10,385,695 | [['D27.505.519.124.035', 'D27.505.954.248.150', 'D27.888.569.035.035'], ['D27.720.470.410.210'], ['D13.444.308.135', 'G05.200.104'], ['G05.200'], ['D08.811.399.403.483', 'D12.776.157.687.375', 'D12.776.660.720.375'], ['D08.811.399.403.741'], ['D13.444.308.425'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Approach to learning disability. | Learning disabilities (LD) is one of the important causes of poor academic performance in school going children. Learning disabilities are developmental disorders that usually manifest during the period of normal education. These disabilities create a significant gap between the true potential and day to day performanc... | ['Adolescent', 'Child', 'Child, Preschool', 'Diagnosis, Differential', 'Female', 'Humans', 'Learning Disabilities', 'Male', 'Patient Care Team', 'Remedial Teaching', 'Risk Factors'] | 11,450,386 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.150.550', 'C23.888.592.604.150.550', 'F03.625.562'], ['N04.590.715'], ['F02.784.629.709', 'I02.903.694'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Glycinebetaine alleviates the chromium toxicity in Brassica oleracea L. by suppressing oxidative stress and modulating the plant morphology and photosynthetic attributes. | Anthropogenic activities are a major source for contaminating the agricultural soil with heavy metals, which can affect physiological and metabolic processes in plants. Among the heavy metals, chromium (Cr) is the most toxic pollutant that negatively affects plants' metabolic activities, growth, and yield. Chromium red... | ['Betaine', 'Biomass', 'Brassica', 'Chromium', 'Hydrogen Peroxide', 'Malondialdehyde', 'Oxidative Stress', 'Photosynthesis', 'Plant Leaves', 'Plant Roots', 'Soil', 'Soil Pollutants'] | 31,820,244 | [['D02.092.877.883.077', 'D02.675.276.125'], ['G16.500.275.157.100', 'N06.230.124.100'], ['B01.650.940.800.575.912.250.157.200'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D02.047.700'], ['G03.673', 'G07... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
NMR-visible intracellular P(i) and phosphoesters during regulation of Na(+)-P(i) cotransport in opossum kidney cells. | There is an inverse relationship between intracellular concentration of P(i) ([P(i)]i) in the kidney and maximum velocity (Vmax) of Na(+)-P(i) cotransport in brush-border membrane vesicles both in P(i)-deprived and growing animals. However, at any given [P(i)]i, the Vmax is substantially higher in growing than in P(i)-... | ['Animals', 'Carrier Proteins', 'Cell Line', 'Insulin-Like Growth Factor I', 'Intracellular Membranes', 'Kidney', 'Magnetic Resonance Spectroscopy', 'Opossums', 'Organophosphates', 'Phosphates', 'Sodium-Phosphate Cotransporter Proteins', 'Symporters'] | 7,943,285 | [['B01.050'], ['D12.776.157'], ['A11.251.210'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['A11.284.149.450', 'A11.284.835.514'], ['A05.810.453'], ['E05.196.867.519'], ['B01.050.150.900.649.573.575'], ['D02.705.400'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endothelial dysfunction in hypercholesterolemia is improved by L-arginine administration: possible role of oxidative stress. | Hypercholesterolemia impairs endothelial function. However, the production/release of nitric oxide from the hypercholesterolemic aorta is reported to be enhanced rather than impaired in animal studies. L-arginine improves endothelial function in hypercholesterolemic subjects. The goal of the present study was to invest... | ['Adult', 'Analysis of Variance', 'Arginine', 'Endothelium, Vascular', 'Humans', 'Hypercholesterolemia', 'Male', 'Observer Variation', 'Oxidative Stress', 'Probability', 'Reference Values', 'Treatment Outcome', 'Vascular Patency', 'Vasoconstriction', 'Vasodilation'] | 11,888,520 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.584.500.500.396'], ['E01.354.753', 'N02.421.450.600', 'N05.715.350.150.675', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Gene expression by human articular chondrocytes cultured in alginate beads. | Culture of articular chondrocytes in alginate beads offers several advantages over culture in monolayer; cells retain their phenotype for 8 months or longer. Earlier studies of chondrocytes cultured in alginate concentrated on collagen and proteoglycan synthesis. However, gene expression by in situ hybridization (ISH) ... | ['Adult', 'Aggrecans', 'Blotting, Western', 'Cartilage, Articular', 'Cells, Cultured', 'Chondrocytes', 'Extracellular Matrix Proteins', 'Humans', 'Immunohistochemistry', 'In Situ Hybridization', 'Infant, Newborn', 'Lectins, C-Type', 'Male', 'Matrix Metalloproteinase 3', 'Matrix Metalloproteinase 8', 'Procollagen', 'Pro... | 11,561,005 | [['M01.060.116'], ['D09.698.735.200.500', 'D12.776.395.650.750.687.100', 'D12.776.503.280.437.100', 'D12.776.860.300.140'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A02.165.407.150', 'A02.835.583.192'], ['A11.251'], ['A11.329.171'], ['D12.776.860.300'], ['B0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
DNA microarray expression analysis of baicalin-induced differentiation of C17.2 neural stem cells. | Identifying baicalin-regulated genes for neuronal differentiation: Baicalin is a potent neuronal-differentiation-inducing compound. This study explored the gene expression regulated through baicalin-induced differentiation of C17.2 neural stem cells by using a DNA microarray followed by qPCR validation. The expression ... | ['Animals', 'Cell Differentiation', 'Cell Line', 'Flavonoids', 'Gene Expression Profiling', 'Mice', 'Neural Stem Cells', 'Oligonucleotide Array Sequence Analysis'] | 22,556,041 | [['B01.050'], ['G04.152'], ['A11.251.210'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['E05.393.332'], ['B01.050.150.900.649.313.992.635.505.500'], ['A11.872.653'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1. | The mechanistic target of rapamycin complex 1 (mTORC1) protein kinase is a master growth regulator that responds to multiple environmental cues. Amino acids stimulate, in a Rag-, Ragulator-, and vacuolar adenosine triphosphatase-dependent fashion, the translocation of mTORC1 to the lysosomal surface, where it interacts... | ['Amino Acid Sequence', 'Amino Acid Transport Systems', 'Arginine', 'HEK293 Cells', 'Humans', 'Lysosomes', 'Mechanistic Target of Rapamycin Complex 1', 'Molecular Sequence Data', 'Monomeric GTP-Binding Proteins', 'Multiprotein Complexes', 'Protein Structure, Tertiary', 'Signal Transduction', 'TOR Serine-Threonine Kinas... | 25,567,906 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.157.530.200', 'D12.776.543.585.200'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.284.430.214.190.875.190.550'], ['D05.500.337', 'D08.811.913.696.620.682.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
In vitro antioxidant and photo-oxidant properties of dipyridamole. | The in vitro antioxidant and photo-oxidant activity of dipyridamole was studied by its effect on superoxide- and singlet oxygen-mediated photohemolysis and viability of neutrophils. Dipyridamole was found to be phototoxic when examined by the photohemolysis on human erythrocytes and on linoleic acid as lipid peroxidati... | ['Antioxidants', 'Dipyridamole', 'Free Radical Scavengers', 'Hemolysis', 'Humans', 'In Vitro Techniques', 'Kinetics', 'Linoleic Acid', 'Photolysis', 'Platelet Aggregation Inhibitors', 'Singlet Oxygen', 'Spectrophotometry, Ultraviolet', 'Superoxides', 'Triamterene', 'Ultraviolet Rays'] | 11,797,818 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D03.383.742.175'], ['D27.505.519.217.500'], ['C23.550.403', 'G12.122.545'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['G01.374.661', 'G02.111.490'], ['D10.251.355.310.515.500', 'D10.251.355.343.500.500'], ['G02.740.685'], ['D27.505.9... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Obesity epidemic: origins and consequences]. | Obesity is a chronic disease with serious health consequences. Initial weight gain is related to behavioural and environmental factors acting on a biological (mainly genetic) predisposition. The evolution of the disease is characterized by the development of an inflammatory organ disease that involves the adipocytes an... | ['Adipose Tissue', 'Energy Metabolism', 'Environment', 'Humans', 'Obesity', 'Respiratory Tract Diseases'] | 16,860,274 | [['A10.165.114'], ['G03.295'], ['G16.500.275', 'N06.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120.699.500'], ['C08']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Preliminary investigations on a new disposable potentiometric biosensor for uric acid. | In this paper, uricase, catalase, and electron mediator were coimmobilized on the surface of the tin oxide (SnO2)/indium tin oxide (ITO) glass, to develop a disposable potentiometric uric acid biosensor. The SnO2/ITO glass was employed as a pH sensor, fabricated by sputtering SnO2 thin films on the ITO glass. 3-Glycidy... | ['Biosensing Techniques', 'Electrochemistry', 'Equipment Design', 'Equipment Failure Analysis', 'Hydrogen-Ion Concentration', 'Microelectrodes', 'Pilot Projects', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Urate Oxidase', 'Uric Acid', 'Urinalysis'] | 16,830,944 | [['E05.601.043'], ['H01.181.529.307'], ['E05.320'], ['E05.325.192'], ['G02.300'], ['E07.305.250.500'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[The expression of nicotinamide phosphoribosyl transferase and vascular endothelial growth factor-A in gastric carcinoma and their clinical significance]. | OBJECTIVES: To study the expression of nicotinamide phosphoribosyl transferase (Nampt) and vascular endothelial growth factor-A (VEGF-A) in gastric carcinoma and investigate their correlations to clinicopathologic features and prognostic significance.METHODS: The proteins of Nampt and VEGF-A in 68 specimens of gastric ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cytokines', 'Female', 'Humans', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Nicotinamide Phosphoribosyltransferase', 'Prognosis', 'Stomach Neoplasms', 'Survival Rate', 'Vascular Endothelial Growth Factor A'] | 23,157,963 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['D08.811.913.400.725.575'], ['E01.789'], ['C04.588.274.476.767', 'C06.301.371.767', 'C... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
SCL interacts with VEGF to suppress apoptosis at the onset of hematopoiesis. | During development, hematopoiesis initiates in the yolk sac through a process that depends on VEGF/Flk1 signaling and on the function of the SCL/Tal1 transcription factor. Here we show that VEGF modifies the developmental potential of primitive erythroid progenitors and prolongs their life span. Furthermore, the surviv... | ['Animals', 'Apoptosis', 'Basic Helix-Loop-Helix Transcription Factors', 'Cell Movement', 'DNA-Binding Proteins', 'Erythrocytes', 'Erythroid Cells', 'Genes, Lethal', 'Hematopoiesis', 'Hematopoietic Stem Cells', 'Mice', 'Proto-Oncogene Proteins', 'T-Cell Acute Lymphocytic Leukemia Protein 1', 'Transcription Factors', 'V... | 14,729,577 | [['B01.050'], ['G04.146.954.035'], ['D12.776.260.103', 'D12.776.930.125'], ['G04.198', 'G07.568.500.180'], ['D12.776.260'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['A11.443'], ['G05.360.340.024.340.350'], ['G04.152.825', 'G09.188.343'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B01.050.150.900.64... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mathematical model of the fission yeast cell cycle with checkpoint controls at the G1/S, G2/M and metaphase/anaphase transitions. | All events of the fission yeast cell cycle can be orchestrated by fluctuations of a single cyclin-dependent protein kinase, the Cdc13/Cdc2 heterodimer. The G1/S transition is controlled by interactions of Cdc13/Cdc2 and its stoichiometric inhibitor, Rum1. The G2/M transition is regulated by a kinase-phosphatase pair, W... | ['Anaphase', 'Cell Cycle', 'Cyclins', 'Fungal Proteins', 'G1 Phase', 'G2 Phase', 'Mathematical Computing', 'Metaphase', 'Mitosis', 'Models, Biological', 'S Phase', 'Schizosaccharomyces', 'Schizosaccharomyces pombe Proteins'] | 9,652,094 | [['G04.144.220.220.687.222', 'G04.144.220.220.781.050', 'G05.113.220.687.250', 'G05.113.220.781.050'], ['G04.144'], ['D12.644.360.262', 'D12.776.167.218', 'D12.776.476.262'], ['D12.776.354'], ['G04.144.500.320'], ['G04.144.500.340'], ['L01.224.680'], ['G04.144.220.220.687.625', 'G04.144.220.220.781.625', 'G05.113.220.6... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Synthesis by mouse peritoneal cells of G-CSF, the differentiation inducer for myeloid leukemia cells: stimulation by endotoxin, M-CSF and multi-CSF. | Normal C57BL mouse peritoneal cells were able to synthesize material with the ability to induce differentiation in colonies of the mouse myelomonocytic leukemia cell line, WEHI-3B. The active factor was provisionally identified biochemically as the normal regulator, granulocyte colony-stimulating factor, G-CSF. Thiogly... | ['Animals', 'Ascitic Fluid', 'Cell Differentiation', 'Cells, Cultured', 'Colony-Stimulating Factors', 'Endotoxins', 'Female', 'Granulocytes', 'Leukemia, Myeloid', 'Lymphocytes', 'Macrophages', 'Male', 'Mice', 'Mice, Inbred Strains', 'Protein Biosynthesis', 'Whole-Body Irradiation'] | 3,887,043 | [['B01.050'], ['A12.207.119'], ['G04.152'], ['A11.251'], ['D12.644.276.374.410.240', 'D12.776.395.240', 'D12.776.467.374.410.240', 'D23.529.374.410.240'], ['D23.946.123.329'], ['A11.118.637.415', 'A11.148.350', 'A11.627.340', 'A15.145.229.637.415', 'A15.378.316.340', 'A15.382.490.315'], ['C04.557.337.539'], ['A11.118.6... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Segmental ischemic colitis in lymphocytic thrombotic venulitis]. | This case illustrates the difficulty of diagnosing a colonic stenosis of ischemic origin. A 70-year-old lady presents with abdominal pain, fever and melaena. Lc are 15.2, ESR 39 mm, CEA 2.7 ng/ml. A barium enema shows a stenosis of the transverse colon that is suspicious of neoplasia. At time of operation, an induratio... | ['Aged', 'Colitis, Ischemic', 'Colon', 'Colonic Diseases', 'Diagnosis, Differential', 'Female', 'Humans', 'Intestinal Obstruction', 'Lymphocytosis', 'Thrombosis', 'Vasculitis', 'Venules'] | 8,226,085 | [['M01.060.116.100'], ['C06.405.205.265.115', 'C06.405.469.158.188.115', 'C14.907.286'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['C06.405.469.158'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531'], ['C15.378.553.475.604'], ['C14.907.355.830'], ['C14.907.940'], ['A07.015.461.92... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Attitudes of Nurses Towards Searching Online for Medical Information for Personal Health Needs: Cross-Sectional Questionnaire Study. | BACKGROUND: Use of online clinical health care information has become part of the skill set required by medical teams. Nurses believe that information quality and availability affect nursing care and methods. However, nurses tend not to exploit professional medical databases for evidence-based medical information for t... | ['Adult', 'Aged', 'Cross-Sectional Studies', 'Delivery of Health Care', 'Female', 'Humans', 'Internet', 'Male', 'Middle Aged', 'Nurses', 'Professionalism', 'Surveys and Questionnaires', 'Young Adult'] | 32,175,910 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['N04.590.374', 'N05.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['M01.060.116.630'], ['M01.526.485.650', 'N02.360.650'], ['K01.752.566.479.171.566', 'N05.350.340.58... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Aldosterone modulates glucocorticoid receptor binding in hippocampal cell cultures via the mineralocorticoid receptor. | The regulation of corticosteroid receptor expression in the rat brain by adrenal steroids remains controversial. The results of in vivo studies [Brinton and McEwen, 1988; Luttge et al., 1989] suggest that activation of type I receptors can modulate both mineralocorticoid (MR; type I) and glucocorticoid (GR; type II) re... | ['Aldosterone', 'Androstanols', 'Animals', 'Binding, Competitive', 'Cells, Cultured', 'Dexamethasone', 'Down-Regulation', 'Hippocampus', 'Kinetics', 'Rats', 'Receptors, Glucocorticoid', 'Receptors, Mineralocorticoid', 'Spironolactone'] | 8,156,410 | [['D04.210.500.745.745.654.062', 'D06.472.040.585.353.118'], ['D04.210.500.054.040'], ['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['A11.251'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['A08.186.211.180.405', 'A08.186.211.200.885.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
5-benzyloxytryptamine: a relatively selective 5-hydroxytryptamine 1D/1B agent. | The ability of nineteen tryptamine derivatives to interact with putative 5-hydroxytryptamine1D (5-HT1D) receptor binding sites in bovine caudate was analyzed. Sixteen of the nineteen agents competed, with variable potency, for these binding sites with Hill slopes of approximately unity. By contrast, 5-carboxyamidotrypt... | ['Animals', 'Binding Sites', 'Cattle', 'Caudate Nucleus', 'Cerebral Cortex', 'Guinea Pigs', 'Indoles', 'Male', 'Radioligand Assay', 'Rats', 'Rats, Inbred Strains', 'Receptors, Neurotransmitter', 'Receptors, Serotonin', 'Serotonin', 'Sulfonamides', 'Sumatriptan', 'Synaptosomes', 'Vasoconstrictor Agents'] | 1,650,872 | [['B01.050'], ['G02.111.570.120'], ['B01.050.150.900.649.313.500.380.271'], ['A08.186.211.200.885.287.249.487.550.184'], ['A08.186.211.200.885.287.500'], ['B01.050.150.900.649.313.992.550'], ['D03.633.100.473'], ['E01.370.225.985', 'E01.370.374.650', 'E01.370.384.720', 'E05.200.985'], ['B01.050.150.900.649.313.992.635.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ectopic adenine nucleotide translocase activity controls extracellular ADP levels and regulates the F1 | Ecto-F1-ATPase is a complex related to mitochondrial ATP synthase which has been identified as a plasma membrane receptor for apolipoprotein A-I (apoA-I), the major protein of high-density lipoprotein (HDL), and has been shown to contribute to HDL endocytosis in several cell types. On hepatocytes, apoA-I binding to ect... | ['Adenosine Diphosphate', 'Adenosine Triphosphate', 'Apolipoprotein A-I', 'Cell Line', 'Cell Line, Tumor', 'Cell Membrane', 'Endocytosis', 'Hep G2 Cells', 'Hepatocytes', 'Humans', 'Lipoproteins, HDL', 'Mitochondrial ADP, ATP Translocases', 'Mitochondrial Proteins', 'Proton-Translocating ATPases', 'Signal Transduction'] | 28,504,211 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['D10.532.091.200.100', 'D12.776.070.400.200.100', 'D12.776.521.120.200.100'], ['A11.251.210'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.149'], ['G04.41... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Semi-rigid Ureteroscopy for the Management of Ureteric Calculi: Our Experience and Complication Encountered. | BACKGROUND: Semi-rigid ureteroscopy lithotripsy have become standard of treatment for ureteral calculi. The aim of this study isto review outcome of Semi-rigidureteroscopy lithotripsy and to report the complications encountered.METHODS: After approval from institutional committee of Public Health Concern Trust Nepal,we... | ['Adolescent', 'Adult', 'Aged', 'Female', 'Humans', 'Lithotripsy', 'Male', 'Middle Aged', 'Nepal', 'Postoperative Complications', 'Retrospective Studies', 'Ureteral Calculi', 'Ureteroscopy'] | 31,455,940 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.600', 'E04.943.500'], ['M01.060.116.630'], ['Z01.252.245.674'], ['C23.550.767'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.52... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[A woman with skin lesions and brain infarcts]. | We present the case of a 58-year-old woman with multiple brain infarcts and livedo racemosa, a distinctive branched and irregular skin discoloration, on the trunk and limbs. Skin biopsy showed intimal proliferation with occlusion of a subcutaneous arteriole. We diagnosed Sneddon's syndrome, a rare neurocutaneous disord... | ['Biopsy', 'Brain', 'Brain Infarction', 'Female', 'Humans', 'Middle Aged', 'Skin', 'Skin Diseases', 'Sneddon Syndrome', 'Vascular Diseases'] | 31,283,121 | [['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A08.186.211'], ['C10.228.140.300.150.477', 'C10.228.140.300.775.200', 'C14.907.253.092.477', 'C14.907.253.855.200', 'C23.550.513.355.250', 'C23.550.717.489.250'], ['B01.050.1... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Conditioning effects of sural nerve stimulation on short and long latency motor evoked potentials in lower limb muscles. | The effects of conditioning sural nerve stimulation on motor evoked potentials (MEPs) in relaxed muscles of the lower limb were examined in 11 healthy adults. The study tested the hypothesis that cutaneous afferent stimulation, in the absence of muscle afferent input, facilitates the short latency MEPs evoked in lower ... | ['Adult', 'Electric Stimulation', 'Electromyography', 'Evoked Potentials', 'Female', 'Humans', 'Leg', 'Male', 'Muscles', 'Reaction Time', 'Sural Nerve'] | 7,533,716 | [['M01.060.116'], ['E05.723.402'], ['E01.370.405.255', 'E01.370.530.255'], ['G07.265.216.500', 'G11.561.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['A02.633', 'A10.690'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['A08.800.800.720.450.760.820.820']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reconstruction of the original mycoflora in pelleted feed by PCR-SSCP and qPCR. | Ground feeds for pigs were investigated for fungal contamination before and after pelleting (subsamples in total n = 24) by cultural and molecular biological methods. A fungal-specific primer pair ITS1/ITS5.8R was used to amplify fungal DNA; PCR products were processed for the PCR-SSCP method. In the resulting acrylami... | ['Animal Feed', 'DNA Primers', 'DNA, Fungal', 'Fungi', 'Polymerase Chain Reaction', 'Polymorphism, Single-Stranded Conformational', 'Real-Time Polymerase Chain Reaction'] | 25,088,501 | [['G07.203.300.300.100', 'J02.500.300.100'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.300'], ['B01.300'], ['E05.393.620.500'], ['G05.365.795.600'], ['E05.393.620.500.706']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Anti-Jo-1 antibody-positive patients show a characteristic necrotizing perifascicular myositis. | Idiopathic inflammatory myopathies can be classified as polymyositis, dermatomyositis, immune-mediated necrotizing myopathy, sporadic inclusion body myositis or non-specific myositis. Anti-Jo-1 antibody-positive patients are assigned to either polymyositis or dermatomyositis suggesting overlapping pathological features... | ['Adult', 'Antibodies, Antinuclear', 'Autoantibodies', 'Dermatomyositis', 'Female', 'Humans', 'Ligases', 'Male', 'Microscopy, Electron, Transmission', 'Middle Aged', 'Muscle, Skeletal', 'Myositis', 'Myositis, Inclusion Body', 'Retrospective Studies', 'Statistics, Nonparametric'] | 26,198,592 | [['M01.060.116'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['C05.651.594.819.500', 'C10.668.491.562.575.500', 'C17.300.250', 'C17.800.185'], ['B01.050.150.900.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effects of euglycemic hyperinsulinemia and amino acid infusion on regional and whole body glucose disposal in man. | We investigated the effects of amino acid infusion on regional and whole body glucose metabolism in 16 normal volunteers, age 32 to 70 years. Ten subjects underwent 140-minute euglycemic insulin infusions at the rate of 1 mU/kg.min with concomitant 10% amino acid infusion. Six volunteers who underwent identical euglyce... | ['Adult', 'Aged', 'Amino Acids', 'Blood Glucose', 'Female', 'Glucagon', 'Glucose', 'Humans', 'Hyperinsulinism', 'Insulin', 'Male', 'Middle Aged', 'Reference Values'] | 1,984,572 | [['M01.060.116'], ['M01.060.116.100'], ['D12.125'], ['D09.947.875.359.448.500'], ['D06.472.699.587.730.500', 'D12.644.548.586.730.500'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['M01.060.116.630'], ['E... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Negative pressure therapy with the ULTRAVAC instillation in the therapy of infected laparotomies with fascitis temporary results of a prospective randomized study. | INTRODUCTION: Negative pressure wound therapy is a healing modality utilizing continuous or intermittently applied vacuum to the wound bed. Nowadays is available a vacuum system supported by an automated instillation with volumetric control. It`s main therapeutic benefit is the dilution of the exudate, which reduces th... | ['Debridement', 'Fasciitis', 'Humans', 'Laparotomy', 'Negative-Pressure Wound Therapy', 'Prospective Studies', 'Wound Healing'] | 31,159,548 | [['E04.176'], ['C05.321'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.406'], ['E02.309.610', 'E04.237.444', 'E04.987.550'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['G16.762.891']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A role of phosphodiesterase-3B pathway in mediating leptin action on proopiomelanocortin and neurotensin neurons in the hypothalamus. | Leptin signaling in the hypothalamus is required for normal food intake and body weight homeostasis. Recent evidence suggests that besides the signal transducer and activator of transcription-3 (STAT3) pathway, several non-STAT3 pathways mediate leptin signaling in the hypothalamus. We have previously demonstrated that... | ['Animals', 'Cyclic Nucleotide Phosphodiesterases, Type 3', 'Gene Expression', 'Hypothalamus', 'Leptin', 'Male', 'Models, Neurological', 'Neurons', 'Neurotensin', 'Phosphodiesterase 3 Inhibitors', 'Phosphodiesterase Inhibitors', 'Pro-Opiomelanocortin', 'Quinolones', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Si... | 20,471,454 | [['B01.050'], ['D08.811.277.352.640.150.300', 'D12.644.360.008.300', 'D12.776.476.008.300'], ['G05.297'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['D06.472.699.042.500', 'D12.644.276.024.500', 'D12.644.548.011.500', 'D12.776.467.024.500', 'D23.529.024.500'], ['E05.599.395.642'], ['A08.675', 'A11.671'], ['D1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neurobiological and psychopathological variables related to emotional instability: a study of their capability to discriminate patients with bulimia nervosa from healthy controls. | OBJECTIVE: To analyze the capability of a set of neurobiological and psychopathological variables to discriminate bulimia nervosa (BN) patients from healthy controls.METHOD: Seventy-five female patients with purging BN and 30 healthy controls were compared for psychopathology (impulsivity, borderline personality traits... | ['Adolescent', 'Adult', 'Biogenic Monoamines', 'Biomarkers', 'Bulimia Nervosa', 'Depression', 'Dexamethasone', 'Female', 'Humans', 'Hydrocortisone', 'Hypothalamo-Hypophyseal System', 'Impulsive Behavior', 'Personality Disorders', 'Personality Inventory', 'Pituitary-Adrenal Function Tests', 'Pituitary-Adrenal System', '... | 21,494,052 | [['M01.060.057'], ['M01.060.116'], ['D02.092.211.215'], ['D23.101'], ['F03.400.250'], ['F01.145.126.350'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['A06.688.357', 'A08.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The directionality of RuvAB-mediated branch migration: in vitro studies with three-armed junctions. | BACKGROUND: The Escherichia coli RuvA and RuvB proteins promote the branch migration of 4-way (Holliday) junctions during genetic recombination. The active complex is a tripartite structure in which RuvA protein is bound to the crossover and is sandwiched between two hexameric rings of RuvB. Branch migration requires A... | ['Bacterial Proteins', 'Base Sequence', 'Binding Sites', 'DNA Footprinting', 'DNA Helicases', 'DNA, Bacterial', 'DNA-Binding Proteins', 'Deoxyribonuclease I', 'Escherichia coli', 'Escherichia coli Proteins', 'Models, Molecular', 'Molecular Sequence Data', 'Molecular Structure', 'Nucleic Acid Conformation', 'Protein Con... | 9,078,376 | [['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['E05.393.300'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['D13.444.308.212'], ['D12.776.260'], ['D08.811.277.352.335.350.250'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['E05.599... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Bactericidal and inhibitory activity of quinupristin/dalfopristin against vancomycin- and gentamicin-resistant Enterococcus faecium. | There is a need for new agents, or combinations of agents, for the treatment of infections caused by vancomycin- and gentamicin-resistant Enterococcus faecium (VGREF) that may be resistant to all available antimicrobial agents. The early in-vitro activity of quinupristin/dalfopristin (30:70)--an injectable streptogrami... | ['Anti-Bacterial Agents', 'Colony Count, Microbial', 'Drug Resistance, Multiple', 'Enterococcus faecium', 'Gentamicins', 'Humans', 'Microbial Sensitivity Tests', 'Vancomycin', 'Virginiamycin'] | 9,511,058 | [['D27.505.954.122.085'], ['E01.370.225.875.220', 'E05.200.875.220'], ['G07.690.773.984.300'], ['B03.353.750.250.250.300', 'B03.510.550.250.250.300'], ['D09.408.051.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['D09.400.420.925', 'D12.644.233.925... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Model selection and estimation of multi-compartment models in diffusion MRI with a Rician noise model. | Multi-compartment models in diffusion MRI (dMRI) are used to describe complex white matter fiber architecture of the brain. In this paper, we propose a novel multi-compartment estimation method based on the ball-and-stick model, which is composed of an isotropic diffusion compartment ("ball") as well as one or more per... | ['Algorithms', 'Brain', 'Computer Simulation', 'Data Interpretation, Statistical', 'Diffusion Tensor Imaging', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Models, Neurological', 'Models, Statistical', 'Nerve Fibers, Myelinated', 'Pattern Recognition, Automated', 'Reproducibility of Result... | 24,684,006 | [['G17.035', 'L01.224.050'], ['A08.186.211'], ['L01.224.160'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['E01.370.350.578.750', 'E01.370.350.825.500.150.500', 'E01.370.376.537.500', 'E05.629.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
hZIP1 zinc uptake transporter down regulation and zinc depletion in prostate cancer. | BACKGROUND: The genetic and molecular mechanisms responsible for and associated with the development and progression of prostate malignancy are largely unidentified. The peripheral zone is the major region of the human prostate gland where malignancy develops. The normal peripheral zone glandular epithelium has the uni... | ['Cation Transport Proteins', 'Cell Line, Tumor', 'Citric Acid', 'Down-Regulation', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lymph Nodes', 'Male', 'Neoplasm Staging', 'Prostatic Neoplasms', 'RNA, Messenger', 'Zinc'] | 16,153,295 | [['D12.776.157.530.450.250', 'D12.776.543.585.450.250'], ['A11.251.210.190', 'A11.251.860.180'], ['D02.241.081.901.434.249'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.549.400', 'A15.382.520.604.412'], ['E01.789.625'], ['C04.588.945.440.77... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Seasonal changes of responses to gonadotropin-releasing hormone analog in expression of growth hormone/prolactin/somatolactin genes in the pituitary of masu salmon. | Gonadotropin-releasing hormone (GnRH) is considered to stimulate secretion of growth hormone (GH), prolactin (PRL), and somatolactin (SL) at particular stages of growth and sexual maturation in teleost fishes. We therefore examined seasonal variation in the pituitary levels of GH/PRL/SL mRNAs, and tried to clarify seas... | ['Animals', 'Drug Implants', 'Female', 'Fish Proteins', 'Gene Expression', 'Glycoproteins', 'Gonadotropin-Releasing Hormone', 'Growth Hormone', 'Male', 'Oncorhynchus', 'Pituitary Gland', 'Pituitary Hormones', 'Prolactin', 'RNA, Messenger', 'Seasons', 'Sex Characteristics', 'Sexual Maturation'] | 12,535,625 | [['B01.050'], ['D26.255.210.315'], ['D12.776.325'], ['G05.297'], ['D09.400.430', 'D12.776.395'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['B01.050.150.900.493.817.750.705.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The Drosophila Jun-N-terminal kinase is required for cell morphogenesis but not for DJun-dependent cell fate specification in the eye. | We cloned and characterized the Drosophila homolog of mammalian Jun-N-terminal kinases (DJNK). We show that DJNK is encoded by basket (bsk). Like hemipterous (hep), which encodes the Drosophila JNK kinase, bsk is required in the embryo for dorsal closure, a process involving coordinate cell shape changes of ectodermal ... | ['Amino Acid Sequence', 'Animals', 'Cell Lineage', 'Drosophila', 'Drosophila Proteins', 'Eye', 'Gene Expression Regulation, Developmental', 'Gene Expression Regulation, Enzymologic', 'Genes, Dominant', 'Mitogen-Activated Protein Kinase Kinases', 'Molecular Sequence Data', 'Morphogenesis', 'Mutation', 'Phenotype', 'Prot... | 8,946,916 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['D12.776.093.500.462'], ['A01.456.505.420', 'A09.371'], ['G05.308.310'], ['G05.308.320'], ['G05.360.340.024.340.240', 'G05.420.320... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
UPF1 is crucial for the infectivity of human immunodeficiency virus type 1 progeny virions. | The SF1 helicase MOV10 is an antiviral factor that is incorporated into human immunodeficiency virus type 1 (HIV-1) virions. We now report that HIV-1 virions also incorporate UPF1, which belongs to the same SF1 helicase subfamily as MOV10 and functions in the nonsense-mediated decay (NMD) pathway. Unlike ectopic MOV10,... | ['HIV-1', 'Host-Pathogen Interactions', 'Humans', 'Mutant Proteins', 'RNA Helicases', 'Trans-Activators', 'Virus Replication'] | 23,785,196 | [['B04.820.650.589.650.350.400'], ['G06.462', 'G16.527.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.602'], ['D08.811.913.696.445.735.720'], ['D12.776.260.755', 'D12.776.930.900', 'D12.776.964.925.984'], ['G06.920.925']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Automatic PAP Mask Sizing with an Error Correcting Autoencoder. | We present the use of an error correcting autoencoder stage to a convolutional neural network model as a means of improving image based automatic Positive Airway Pressure (PAP) mask sizing accuracy. A single convolutional layer neural network was pre-trained using MUCT dataset and transfer learning was applied to mitig... | ['Humans', 'Image Processing, Computer-Assisted', 'Machine Learning', 'Masks', 'Neural Networks, Computer', 'Positive-Pressure Respiration'] | 31,946,674 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['G17.035.250.500', 'L01.224.050.375.530'], ['E07.325.877.500', 'E07.700.500', 'E07.858.594.750', 'J01.637.708.560.782'], ['G17.485', 'L01.224.050.375.605'], ['E02.041.625.790', 'E02.880.820.790']] | ['Organisms [B]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Use-dependent loss of active sympathetic neurogenic vasodilation after nitric oxide synthase inhibition in conscious rats. Evidence for the presence of preformed stores of nitric oxide-containing factors. | In this study, we examined whether air-jet stress-induced active sympathetic hindlimb vasodilation in conscious rats involves the release of preformed stores of nitric oxide-containing factors. We determined the effects of repeated episodes of air-jet stress (six episodes given 5 minutes apart) on mean arterial pressur... | ['Air', 'Animals', 'Behavior, Animal', 'Cysteine', 'Hemodynamics', 'Hindlimb', 'Male', 'NG-Nitroarginine Methyl Ester', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Nitroprusside', 'Physical Stimulation', 'Rats', 'Rats, Sprague-Dawley', 'S-Nitrosothiols', 'Stress, Mechanical', 'Sympathetic Nervous System', 'Vasodilation'] | 8,794,815 | [['G16.500.275.063.150', 'N06.230.300.100.150'], ['B01.050'], ['F01.145.113'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['G09.330.380'], ['A13.473'], ['D12.125.068.050.525', 'D12.125.095.104.525'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['D08.8... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Biological pathway selection through Bayesian integrative modeling. | Pathway analysis has become a central approach to understanding the underlying biology of differentially expressed genes. As large amounts of microarray data have been accumulated in public repositories, flexible methodologies are needed to extend the analysis of simple case-control studies in order to place them in co... | ['Animals', 'Bayes Theorem', 'Databases, Genetic', 'Gene Expression Profiling', 'Humans', 'Mice', 'Mice, Inbred C57BL', 'Models, Genetic', 'Oligonucleotide Array Sequence Analysis', 'Signal Transduction', 'Transcriptome'] | 24,937,506 | [['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Outcomes in kidney transplant recipients from older living donors. | BACKGROUND: Previous studies demonstrate that graft survival from older living kidney donors (LD; age>60 years) is worse than younger LD but similar to deceased standard criteria donors (SCD). Limited sample size has precluded more detailed analyses of transplants from older LD.METHODS: Using the United Network for Org... | ['Adult', 'Age Factors', 'Aged', 'Databases, Factual', 'Donor Selection', 'Female', 'Graft Survival', 'Humans', 'Kidney Transplantation', 'Living Donors', 'Male', 'Middle Aged', 'Risk Factors', 'Time Factors', 'Transplant Recipients', 'Treatment Outcome', 'United States', 'Young Adult'] | 25,594,554 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E04.936.537.500', 'N02.421.911.600'], ['G12.875.545.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['M01.898.656'], ['M01.0... | ['Named Groups [M]', 'Health Care [N]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Treatment of the nonpsychotic chronic patient: a problem of interactive fit. | Nonpsychotic chronic adult patients are troublesome, not only because of their psychosocial dysfunction, cognitive and affective impairments, and behavioral problems, but also because they fail the expectations and values of health care providers. The concept of interactive fit is proposed to facilitate the therapeutic... | ['Attitude of Health Personnel', 'Behavior Therapy', 'Chronic Disease', 'Humans', 'Patient Care Team', 'Professional-Patient Relations', 'Psychotherapy', 'Psychotic Disorders'] | 3,674,214 | [['F01.100.050', 'N05.300.100'], ['F04.754.137'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.715'], ['F01.829.401.650', 'N05.300.660'], ['F04.754'], ['F03.700.675']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A Case of Granulocytic Sarcoma or Extramedullary Acute Myelomonocytic Leukemia of the Gallbladder. | BACKGROUND Granulocytic sarcoma, or 'chloroma,' due to extramedullary acute myeloid leukemia (AML) or due to acute myelomonocytic leukemia (AML M5), is rare and is associated with a poor prognosis. This report is of a case of granulocytic sarcoma of the gallbladder and describes the approach to diagnosis and treatment.... | ['Aged', 'Diagnosis, Differential', 'Female', 'Gallbladder Neoplasms', 'Humans', 'Leukemia, Myelomonocytic, Acute', 'Sarcoma, Myeloid'] | 30,352,989 | [['M01.060.116.100'], ['E01.171'], ['C04.588.274.120.401', 'C06.130.320.401', 'C06.130.564.401', 'C06.301.120.401'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.539.520'], ['C04.557.337.539.775', 'C04.557.450.795.853']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Autografts from the foot for reconstruction of the scapholunate interosseous ligament. | A cadaveric study was undertaken to identify a potential autograft for use in repairing the ruptured scapholunate interosseous ligament. Three ligament complexes (the dorsal metatarsal ligament of the fourth and fifth metatarsals, a dorsal tarsometatarsal ligament, and the dorsal calcaneocuboid ligament) were chosen as... | ['Aged', 'Aged, 80 and over', 'Biomechanical Phenomena', 'Carpal Bones', 'Humans', 'Ligaments, Articular', 'Lunate Bone', 'Male', 'Middle Aged', 'Tensile Strength', 'Transplantation, Autologous', 'Wrist Injuries'] | 8,583,071 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G01.154.090', 'G01.374.089'], ['A02.835.232.087.319.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.513.514', 'A02.835.583.512', 'A10.165.669.514'], ['A02.835.232.087.319.150.500'], ['M01.060.116.630'], ['G01.374.850'], ['E04.936.664'], ['C26.088.906']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Nicotine aggravates the brain postischemic inflammatory response. | A substantial body of evidence suggests that nicotine adversely affects cerebral blood flow and the blood-brain barrier and is a risk factor for stroke. The present study investigated the effect of nicotine on cerebrovascular endothelium under basal and ischemia/reperfusion injury under in vivo condition. Nicotine (2 m... | ['Animals', 'Blood-Brain Barrier', 'Brain Infarction', 'Cell Adhesion Molecules', 'Chemotaxis, Leukocyte', 'Cytokines', 'Encephalitis', 'Endothelium, Vascular', 'Hypoxia-Ischemia, Brain', 'Interleukin-1beta', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Nicotine', 'Reperfusion Injury'] | 21,239,632 | [['B01.050'], ['A07.035', 'A08.186.211.035'], ['C10.228.140.300.150.477', 'C10.228.140.300.775.200', 'C14.907.253.092.477', 'C14.907.253.855.200', 'C23.550.513.355.250', 'C23.550.717.489.250'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['G04.198.424.233'], ['D12.644.276.374', 'D12.776.467.374',... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Making it work: the application of time as a public health control in the field. | Time as a public health control (TPHC) is increasingly being recognized as a viable alternative to temperature control for potentially hazardous foods in the developed world. This is reflected by recent changes to food regulations and other pertinent health legislation in both Canada and abroad. Considerable ambiguity ... | ['Alberta', 'Consumer Product Safety', 'Food Inspection', 'Food Services', 'Foodborne Diseases', 'Humans', 'Legislation, Food', 'Temperature', 'Time Factors'] | 18,807,821 | [['Z01.107.567.176.064'], ['N06.850.210'], ['J01.576.423.850.730.500.500', 'N06.850.601.500.500', 'N06.850.780.200.800.325'], ['J01.576.423.500'], ['C25.723.415'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.706.615.412'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', '... | ['Geographicals [Z]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Sleep and depression in combat-related PTSD inpatients. | The sleep of 27 unmedicated Vietnam combat-related posttraumatic stress disorder (PTSD) inpatients was monitored for 3 nights. Depressive comorbidity was considered both as a diagnostic category using DMS-III-R criteria, and as a continuous variable using the Beck Depression Inventory (BDI). Data collected included sle... | ['Adult', 'Combat Disorders', 'Comorbidity', 'Depressive Disorder', 'Electromyography', 'Humans', 'Male', 'Middle Aged', 'Polysomnography', 'Psychiatric Status Rating Scales', 'Reaction Time', 'Sleep Wake Disorders', 'Sleep, REM', 'Veterans', 'Vietnam'] | 8,837,979 | [['M01.060.116'], ['F03.950.750.249'], ['N05.715.350.225', 'N06.850.490.687'], ['F03.600.300'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.520.625'], ['F04.711.513.653'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['C10.886'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of gonadal steroid hormones on plasma growth hormone concentrations in sexually immature rainbow trout, Oncorhynchus mykiss. | In the present study we investigated the effects of gonadal steroid hormones on plasma growth hormone (GH), triiodothyronine (T3), and thyroxine (T4) levels in steroid-primed sexually immature rainbow trout, Oncorhynchus mykiss, in order to determine whether changes in plasma GH and thyroid hormone levels during sexual... | ['Aging', 'Animals', 'Calcium', 'Delayed-Action Preparations', 'Dihydrotestosterone', 'Drug Implants', 'Estradiol', 'Gonadal Steroid Hormones', 'Growth Hormone', 'Methyltestosterone', 'Oncorhynchus mykiss', 'Testosterone', 'Thyroxine', 'Time Factors', 'Triiodothyronine'] | 9,038,257 | [['G07.345.124'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D26.255.210', 'E02.319.300.253'], ['D04.210.500.054.040.248', 'D06.472.334.851.968.964'], ['D26.255.210.315'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D06.472.334.851'], ['D06.472.699.631.525.425', 'D12.644.548.691... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Robust 3D DNA FISH using directly labeled probes. | 3D DNA FISH has become a major tool for analyzing three-dimensional organization of the nucleus, and several variations of the technique have been published. In this article we describe a protocol which has been optimized for robustness, reproducibility, and ease of use. Brightly fluorescent directly labeled probes are... | ['Allyl Compounds', 'Animals', 'DNA', 'DNA Probes', 'Fluorescent Dyes', 'Imaging, Three-Dimensional', 'In Situ Hybridization, Fluorescence', 'Mice', 'Uridine Triphosphate'] | 23,978,815 | [['D02.455.326.271.122'], ['B01.050'], ['D13.444.308'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['E01.370.350.400', 'L01.224.308.410'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Rabies-like inclusions in dogs. | Inclusion bodies, indistinguishable from rabies inclusion bodies (Negri bodies), were found in the brains of 8 nonrabid dogs. The inclusions were compared to Negri bodies present in neurons of rabies-positive animals and examined for the presence of rabies virus by a combination of immunoperoxidase staining (7 cases), ... | ['Animals', 'Antigens, Viral', 'Brain', 'Cerebral Cortex', 'Diagnosis, Differential', 'Dog Diseases', 'Dogs', 'Immunoenzyme Techniques', 'Inclusion Bodies, Viral', 'Microscopy, Electron', 'Neurons', 'Purkinje Cells', 'Rabies', 'Rabies virus', 'Thalamus'] | 2,488,717 | [['B01.050'], ['D23.050.327'], ['A08.186.211'], ['A08.186.211.200.885.287.500'], ['E01.171'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['A11.284.420.390', 'G06.920.400'], ['E01.370.350.515.402', 'E05.595.402'], ['A08.675', 'A11.671'], ['A08.186... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibitory amino acid effects upon cortical evoked potentials. | The amplitude of both P1 and N1 waves of the cortical evoked potentials are significantly increased by topical application of GABA and taurine but not of glycine. This suggests a possible depressant effect of both GABA and taurine at superficial cortical layers. | ['Animals', 'Cerebral Cortex', 'Electric Stimulation', 'Evoked Potentials', 'Glycine', 'Rats', 'Taurine', 'gamma-Aminobutyric Acid'] | 4,062,064 | [['B01.050'], ['A08.186.211.200.885.287.500'], ['E05.723.402'], ['G07.265.216.500', 'G11.561.200.500'], ['D12.125.481'], ['B01.050.150.900.649.313.992.635.505.700'], ['D02.455.326.146.100.850', 'D02.886.645.600.055.850'], ['D02.241.081.114.500.350', 'D12.125.190.350']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The association between arsenic exposure from drinking water and cerebrovascular disease mortality in Taiwan. | BACKGROUND: Chronic arsenic exposure is associated with a variety of diseases, including cancer, peripheral vascular disease, and diabetes. However, its association with cerebrovascular diseases (CVD) has not yet been resolved. The aim of this study is to explore this association in Taiwan using nation-wide data.MATERI... | ['Adult', 'Aged', 'Aged, 80 and over', 'Arsenic Poisoning', 'Cerebrovascular Disorders', 'Environmental Exposure', 'Female', 'Humans', 'Male', 'Middle Aged', 'Sex Factors', 'Taiwan', 'Water Pollutants, Chemical', 'Water Supply'] | 20,561,663 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.720.475.150', 'C25.723.098'], ['C10.228.140.300', 'C14.907.253'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N05.715.350.675', 'N06.850.490.875'], ['Z01.252.474.872', 'Z01.639.850'], ['D27.888.284.903... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Focal versus distributed temporal cortex activity for speech sound category assignment. | Percepts and words can be decoded from distributed neural activity measures. However, the existence of widespread representations might conflict with the more classical notions of hierarchical processing and efficient coding, which are especially relevant in speech processing. Using fMRI and magnetoencephalography duri... | ['Acoustic Stimulation', 'Adult', 'Aged', 'Brain Mapping', 'Case-Control Studies', 'Epilepsy', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Magnetoencephalography', 'Male', 'Phonetics', 'Speech Perception', 'Temporal Lobe', 'Young Adult'] | 29,363,598 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Thymic cyst with elevated SLX levels in serum and cystic fluid]. | A 24-year-old man was admitted to our hospital in June 1996 with complaints of anterior chest discomfort. Chest X-ray films on admission showed an abnormal mediastinal shadow with well-defined margin. Chest X-ray examinations about 6 weeks earlier had not detected any abnormalities. Laboratory tests on admission showed... | ['Adult', 'Biomarkers, Tumor', 'Carcinoembryonic Antigen', 'Humans', 'Lewis X Antigen', 'Male', 'Mediastinal Cyst'] | 10,540,840 | [['M01.060.116'], ['D23.101.140'], ['D12.776.395.550.200.210', 'D12.776.543.550.200.210', 'D23.050.285.329', 'D23.050.301.350.210', 'D23.101.140.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D23.050.285.050.050', 'D23.050.301.264.900.050', 'D23.050.301.264.965.500', 'D23.050.301.290.544.059', 'D23.050.550.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Circadian clocks are resounding in peripheral tissues. | Circadian rhythms are prevalent in most organisms. Even the smallest disturbances in the orchestration of circadian gene expression patterns among different tissues can result in functional asynchrony, at the organism level, and may to contribute to a wide range of physiologic disorders. It has been reported that as ma... | ['Adipose Tissue', 'Algorithms', 'Animals', 'Circadian Rhythm', 'Computational Biology', 'Gene Expression Regulation', 'Liver', 'Mice', 'Models, Statistical', 'Obesity', 'Oligonucleotide Array Sequence Analysis', 'Oscillometry', 'Stochastic Processes', 'Transcription, Genetic'] | 16,532,060 | [['A10.165.114'], ['G17.035', 'L01.224.050'], ['B01.050'], ['G07.180.562.190'], ['H01.158.273.180', 'L01.313.124'], ['G05.308'], ['A03.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Is public housing the cause of poor health or a safety net for the unhealthy poor? | Research has shown that public housing residents have the worst health of any population in the USA. However, it is unclear what the cause of that poor health is among this population. The purpose of this paper is to investigate the association between public housing and health conditions: specifically, we ask if resid... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Behavioral Risk Factor Surveillance System', 'Chronic Disease', 'Female', 'Georgia', 'Health Status Disparities', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Poverty', 'Prospective Studies', 'Public Housing', 'Risk Factors', 'Urban Population', 'Young Adult... | 20,585,883 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.308.980.438.149', 'N05.715.360.300.800.438.149', 'N06.850.520.308.980.438.149'], ['C23.550.291.500'], ['Z01.107.567.875.075.250', 'Z01.107.567.875.750.370'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['B0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Natural killer cell cytotoxicity in elderly humans after influenza immunization. | Previous studies have reported that human natural killer (NK) cytotoxicity can be augmented by either in vitro stimulation with influenza virus antigens or in vivo administration of killed influenza vaccine. The study demonstrating the latter conclusion reported an increase in NK cytotoxicity lasting for 4 weeks postva... | ['Aged', 'Aged, 80 and over', 'Aging', 'Antibodies, Viral', 'CD56 Antigen', 'Cytotoxicity, Immunologic', 'Humans', 'In Vitro Techniques', 'Influenza Vaccines', 'Killer Cells, Natural', 'Orthomyxoviridae', 'Time Factors'] | 8,770,513 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D12.776.395.550.200.250.520.156', 'D12.776.543.550.200.250.520.156', 'D23.050.301.264.894.156', 'D23.050.301.350.250.520.156', 'D23.101.100.894.156'], ['G12.28... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Spontaneously ruptured uterine angioleiomyoma. | Angioleiomyoma is an uncommon type of leiomyoma of the uterus that originates from smooth muscle cells and contains thick-walled vessels. A 45-year-old woman with the complaint of lower abdominal pain was admitted to the hospital. In the operation a ruptured, bleeding uterine tumor was seen. She underwent total hystere... | ['Angiomyoma', 'Antihypertensive Agents', 'Diagnosis, Differential', 'Female', 'Fibroma', 'Hemorrhage', 'Humans', 'Hypertension', 'Immunohistochemistry', 'Lipoma', 'Middle Aged', 'Rupture, Spontaneous', 'Uterine Neoplasms'] | 16,554,917 | [['C04.557.450.590.450.125'], ['D27.505.954.411.162'], ['E01.171'], ['C04.557.450.565.590.340'], ['C23.550.414'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Biomechanics: deadly strike mechanism of a mantis shrimp. | Stomatopods (mantis shrimp) are well known for the feeding appendages they use to smash shells and impale fish. Here we show that the peacock mantis shrimp (Odontodactylus scyllarus) generates an extremely fast strike that requires major energy storage and release, which we explain in terms of a saddle-shaped exoskelet... | ['Animals', 'Biomechanical Phenomena', 'Decapoda', 'Eating', 'Extremities', 'Movement', 'Predatory Behavior'] | 15,103,366 | [['B01.050'], ['G01.154.090', 'G01.374.089'], ['B01.050.500.131.365.190'], ['G07.203.650.283', 'G10.261.330'], ['A01.378'], ['G07.568', 'G11.427.410'], ['F01.145.113.111.600', 'F01.145.113.252.520']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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