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Sleep/wake cycles in the dark: sleep recorded by polysomnography in 26 totally blind subjects compared to controls. | OBJECTIVES: To evaluate subjective sleep difficulties and nocturnal sleep with polysomnography in 26 completely blind subjects, living in normal social environments and to compare the findings with those of matched controls.METHODS: Twenty-six blind individuals with no light perception and free-running melatonin rhythm... | ['Adult', 'Blindness', 'Darkness', 'Female', 'Humans', 'Male', 'Marital Status', 'Melatonin', 'Middle Aged', 'Occupations', 'Polysomnography', 'Reaction Time', 'Reference Values', 'Sleep', 'Sleep Wake Disorders', 'Socioeconomic Factors', 'Time Factors', 'Wakefulness'] | 12,350,437 | [['M01.060.116'], ['C10.597.751.941.162', 'C11.966.075', 'C23.888.592.763.941.162'], ['G01.590.540.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.315.500', 'I01.240.361.500', 'I01.880.853.150.423.500', 'N01.224.361.500', 'N01.824.308.500'], ['D03.633.100.473.914.481', 'D06.472.506'], ['M01.060.11... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Parietal Fast Sleep Spindle Density Decrease in Alzheimer's Disease and Amnesic Mild Cognitive Impairment. | Several studies have identified two types of sleep spindles: fast (13-15 Hz) centroparietal and slow (11-13 Hz) frontal spindles. Alterations in spindle activity have been observed in Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI). Only few studies have separately assessed fast and slow spindles in these ... | ['Aged', 'Alzheimer Disease', 'Amnesia', 'Attention', 'Brain', 'Brain Waves', 'Cognition', 'Cognitive Dysfunction', 'Electroencephalography', 'Female', 'Humans', 'Male', 'Neuropsychological Tests', 'Sleep'] | 27,066,274 | [['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['C10.597.606.525.100', 'C23.888.592.604.529.100', 'F01.700.625.100', 'F03.615.200'], ['F02.830.104.214'], ['A08.186.211'], ['E01.370.376.300.150', 'E01.370.405.245.287', 'G07.265.087', 'G11.561.127'], ['F02.463.188'], ['F03.615.250.70... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Action imitation changes perceptual alternations in binocular rivalry. | Binocular rivalry is a visual phenomenon in which perception alternates between two different monocular images presented to each of the two eyes. Here, we propose using this phenomenon as a method to study the relation between action execution and action perception. In our experiment, a simple background (a checkerboar... | ['Adult', 'Analysis of Variance', 'Attention', 'Female', 'Humans', 'Imitative Behavior', 'Male', 'Models, Psychological', 'Motor Activity', 'Photic Stimulation', 'Time Factors', 'Vision Disparity', 'Visual Perception'] | 24,870,450 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F02.830.104.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.510'], ['E05.599.695'], ['F01.145.632', 'G11.427.410.698'], ['E05.723.729'], ['G01.910.857'], ['F02.463.593.778.255.780', 'F02.463.593.932.877', 'G14.930']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A stopped-flow clinical analyzer in which immobilized-enzyme reaction loops are used. | A stopped-flow clinical analyzer is described that makes use of a reaction loop containing immobilized enzyme(s) for the determination of the analyte/substrate. The analyzer has been evaluated by determining glucose with immobilized glucose oxidase. The stopped-flow mixing system was constructed at a current cost of le... | ['Blood Glucose', 'Chemistry, Clinical', 'Enzymes, Immobilized', 'Glucose Oxidase', 'Humans', 'Methods', 'Spectrophotometry'] | 858,193 | [['D09.947.875.359.448.500'], ['H01.181.341'], ['D08.811.180', 'D12.776.463.500'], ['D08.811.682.047.239'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['E05.196.712.726', 'E05.196.867.826']] | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Towards ending preventable maternal deaths by 2035. | Maternal mortality has been reduced by half from 1990 to 2010, yet a woman in sub-Saharan Africa has a lifetime risk of maternal death of 1 in 39 compared with around 1 in 10,000 in industrialized countries. Annual rates of reduction of maternal mortality of over 10% have been achieved in several countries. Highly cost... | ['Africa South of the Sahara', 'Cost-Benefit Analysis', 'Delivery, Obstetric', 'Female', 'Humans', 'Infant, Newborn', 'Maternal Death', 'Maternal Mortality', 'Maternal-Child Health Centers', 'Pregnancy', 'Prenatal Care', 'Primary Prevention', 'Reproductive Health Services'] | 25,565,508 | [['Z01.058.290'], ['N03.219.151.125'], ['E04.520.252'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C13.703.401', 'C23.550.260.730.500', 'I01.880.735.607.500'], ['E05.318.308.985.550.500', 'N01.224.935.698.653', 'N06.850.505.400.975.550.500', 'N06.850.520.308.985.550.500'], ['N02.278.035.310... | ['Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Pabp binds to the osk 3'UTR and specifically contributes to osk mRNA stability and oocyte accumulation. | RNA localization is tightly coordinated with RNA stability and translation control. Bicaudal-D (Bic-D), Egalitarian (Egl), microtubules and their motors are part of a Drosophila transport machinery that localizes mRNAs to specific cellular regions during oogenesis and embryogenesis. We identified the Poly(A)-binding pr... | ["3' Untranslated Regions", 'Adenine', 'Animals', 'Blastoderm', 'Body Patterning', 'Drosophila Proteins', 'Drosophila melanogaster', 'Female', 'Gene Expression Regulation, Developmental', 'Haploinsufficiency', 'Oocytes', 'Oogenesis', 'Phenotype', 'Poly(A)-Binding Proteins', 'Protein Binding', 'Protein Transport', 'RNA ... | 21,782,810 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['D03.633.100.759.138'], ['B01.050'], ['A16.331.024'], ['G07.345.500.100'], ['D12.776.093.500.462'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G05.308.310'], ['G05.365.590.029.530.587'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spatial properties of binocular neurones in the human visual system. | The spatial properties of human binocular mechanisms were investigated using the technique of subthreshold summation. Isolation of binocular mechanisms was achieved by means of interocular stimulus presentation. The contrast detection threshold for a sinusoidal test grating viewed by one eye was found to be reduced by ... | ['Humans', 'Models, Biological', 'Ocular Physiological Phenomena', 'Pattern Recognition, Visual', 'Space Perception'] | 838,010 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['G14'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F02.463.593.778']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Apocrine (cutaneous) sweat gland carcinoma of axilla with signet ring cells: a diagnostic dilemma on fine-needle aspiration cytology. | Carcinoma arising in the apocrine sweat glands is rare and there are few reports describing the cytological features of this neoplasm. We describe the cytological features of a histologically confirmed apocrine carcinoma occurring in a 55-year-old man who presented with an ulcerated mass in the right axilla. Fine-needl... | ['Adenocarcinoma', 'Axilla', 'Biopsy, Fine-Needle', 'Carcinoma, Signet Ring Cell', 'Diagnosis, Differential', 'Humans', 'Male', 'Middle Aged', 'Sweat Gland Neoplasms'] | 18,773,442 | [['C04.557.470.200.025'], ['A01.378.800.090'], ['E01.370.225.500.384.100.119.500', 'E01.370.225.998.054.119.500', 'E01.370.388.100.100.500', 'E04.074.119.500', 'E04.665.100.500', 'E05.200.500.384.100.119.500', 'E05.200.998.054.119.500', 'E05.242.384.100.119.500'], ['C04.557.470.200.025.415', 'C04.557.470.590.415'], ['E... | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Validity of the Telephone Interview for Cognitive Status (TICS) in post-stroke subjects. | BACKGROUND: Cognitive impairment and dementia are very common after stroke. Telephone screening has potential advantages for clinical follow-up and population-based research in this group. We wished to test the validity of the Telephone Interview for Cognitive Status (TICS) for cognitive testing in post-stroke subjects... | ['Aged', 'Aged, 80 and over', 'Cerebrovascular Disorders', 'Cognition Disorders', 'Dementia', 'Humans', 'Interview, Psychological', 'Middle Aged', 'Psychiatric Status Rating Scales', 'Psychometrics', 'Remote Consultation', 'Sensitivity and Specificity', 'Telephone'] | 14,716,702 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300', 'C14.907.253'], ['F03.615.250'], ['C10.228.140.380', 'F03.615.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.669.599'], ['M01.060.116.630'], ['F04.711.513.653'], ['F04.711.780'], ['L01.178.847.652.550', 'N04.452.758.849.550', 'N04.590.374... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Differential diagnosis of chronic fatigue in children: behavioral and emotional dimensions. | A battery of self-report questionnaires and structured diagnostic interviews was administered to 20 children and adolescents who presented to a pediatric specialty clinic with chronic fatigue. Matched groups of healthy and depressed control subjects (aged 8 to 19 years) were also studied. Criteria were established to i... | ['Adolescent', 'Affective Symptoms', 'Child', 'Child Behavior Disorders', 'Diagnosis, Differential', 'Fatigue Syndrome, Chronic', 'Female', 'Humans', 'Life Change Events', 'Male', 'Patient Care Team', 'Personality Assessment', 'Self Concept', 'Sick Role', 'Somatoform Disorders'] | 8,675,709 | [['M01.060.057'], ['F01.145.126.100'], ['M01.060.406'], ['F03.625.141'], ['E01.171'], ['C01.925.330', 'C05.651.310', 'C10.228.440.600', 'C10.668.364'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458.410'], ['N04.590.715'], ['F04.513'], ['F01.752.747.792'], ['F01.829.316.616.751'], ['F03.875']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Developmental anatomy and auxin response of lateral root formation in Ceratopteris richardii. | The homosporous fern Ceratopteris richardii exhibits a homorhizic root system where roots originate from the shoot system. These shoot-borne roots form lateral roots (LRs) that arise from the endodermis adjacent to the xylem poles, which is in contrast to flowering plants where LR formation arises from cell division in... | ['Flowers', 'Indoleacetic Acids', 'Plant Roots', 'Plant Shoots', 'Pteridaceae'] | 14,754,921 | [['A18.024.249.500'], ['D03.066.288', 'D03.633.100.473.404'], ['A18.400'], ['A18.024.875'], ['B01.650.940.800.575.912.063.750']] | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of different yeast cell-wall mutants on performance and protection against pathogenic bacteria (Vibrio campbellii) in gnotobiotically-grown Artemia. | A selection of isogenic yeast strains (with deletion for genes involved in cell-wall synthesis) was used to evaluate their nutritional and immunostimulatory characteristics for gnotobiotically-grown Artemia. In the first set of experiments the nutritional value of isogenic yeast strains (effected in mannoproteins, gluc... | ['Adjuvants, Immunologic', 'Animal Feed', 'Animals', 'Artemia', 'Cell Wall', 'Chitin', 'Germ-Free Life', 'Membrane Glycoproteins', 'Saccharomyces cerevisiae', 'Survival Analysis', 'Vibrio', 'beta-Glucans'] | 17,240,162 | [['D27.505.696.477.067'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B01.050.500.131.365.060.050'], ['A11.284.183'], ['D05.750.078.139', 'D09.698.211'], ['G06.320'], ['D12.776.395.550', 'D12.776.543.550'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['E05.318.740.998', 'N05.715.360.750.795', 'N0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Angiosarcoma, porphyria cutanea tarda, and probable chloracne in a worker exposed to waste oil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin. | A worker developed angiosarcoma, porphyria cutanea tarda, and skin lesions characteristic of mild chloracne. About 10 years earlier he had been employed at a truck terminal in Saint Louis, Missouri, at a time when it was sprayed with waste oil contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). The occurrence... | ['Acne Vulgaris', 'Hemangiosarcoma', 'Humans', 'Industrial Oils', 'Male', 'Middle Aged', 'Occupational Diseases', 'Occupational Exposure', 'Polychlorinated Dibenzodioxins', 'Porphyria Cutanea Tarda', 'Time Factors', 'Weight Loss'] | 8,104,464 | [['C17.800.030.150', 'C17.800.794.111'], ['C04.557.450.795.390', 'C04.557.645.390'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.637.450'], ['M01.060.116.630'], ['C24'], ['N06.850.460.350.600'], ['D02.309.500.450', 'D03.633.300.786'], ['C06.552.830.100', 'C16.320.850.742.250', 'C17.800.827.742.250', 'C18.452... | ['Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Impact of Prophylaxis on Bone Mineral Metabolism in Children With Hemophilia. | In this study, we aimed to investigate changes in calcium (Ca) metabolism in hemophilia patients (PWH). We also aimed to investigate the importance of diagnosis and treatment of factors impairing calcium metabolism and the significance of early diagnosis and prophylaxis with respect to these subjects. For all patients,... | ['Adolescent', 'Adult', 'Alkaline Phosphatase', 'Biomarkers', 'Bone Density', 'Bone Diseases, Metabolic', 'Bone Remodeling', 'Calcium', 'Child', 'Child, Preschool', 'Female', 'Hemophilia A', 'Humans', 'Infant', 'Male', 'Phosphorus', 'Vitamin D'] | 30,789,845 | [['M01.060.057'], ['M01.060.116'], ['D08.811.277.352.650.035'], ['D23.101'], ['G11.427.100'], ['C05.116.198', 'C18.452.104'], ['G11.427.213', 'G16.762.150'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['M01.060.406'], ['M01.060.406.448'], ['C15.378.100.100.500', 'C15.378.100.141.500', 'C15.378.463.500', 'C1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Focal sclerosis of hypertrophied glomeruli in solitary functioning kidneys of humans. | Morphometric data on glomerular size are presented on three patients with solitary functioning kidneys and one with bilateral oligomeganephronic hypoplasia. Renal biopsy of each of two patients with a congenitally absent kidney (unilateral renal agenesis) and a patient with oligomeganephronie, all with proteinuria and ... | ['Adult', 'Biopsy', 'Female', 'Glomerulonephritis', 'Glomerulosclerosis, Focal Segmental', 'Humans', 'Hypertrophy', 'Kidney', 'Kidney Glomerulus', 'Male', 'Middle Aged', 'Nephrons'] | 4,003,392 | [['M01.060.116'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C12.777.419.570.363', 'C13.351.968.419.570.363'], ['C12.777.419.570.363.660', 'C13.351.968.419.570.363.640'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Community participation in primary care in Ireland: the need for implementation research. | There are now several decades of history of community participation in health, with significant international evidence to suggest that there is much to be gained by primary health services and disadvantaged communities working in partnership. In this paper we provide an overview of community participation in primary ca... | ['Community Participation', 'Community-Institutional Relations', 'Health Policy', 'Humans', 'Ireland', 'Organizational Case Studies', 'Organizational Innovation', 'Poverty Areas', 'Primary Health Care', 'Program Development', 'Program Evaluation'] | 22,717,410 | [['N02.421.143.212', 'N03.540.245.360'], ['N04.452.822.210'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.467', 'Z01.639.587'], ['N03.349.380.710', 'N05.715.360.455'], ['N04.452.610'], ['I01.880.853.996.535.550', 'N01.824.600.550'... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
The Ross procedure--valvular pathology of synchronous pulmonary autograft and homograft insufficiency. | We report the morphological changes in a patient with combined pulmonary autograft and homograft dysfunction after 9 years of implantation. The case highlights long-term adaptive changes in the autograft to withstand systemic blood pressure with formation of exuberant pannus rich in elastic tissue. In the homograft, ma... | ['Heart Valve Prosthesis', 'Heart Valve Prosthesis Implantation', 'Humans', 'Male', 'Middle Aged', 'Pulmonary Valve', 'Pulmonary Valve Insufficiency', 'Transplantation, Autologous', 'Transplantation, Homologous', 'Treatment Outcome'] | 17,651,782 | [['E07.695.310'], ['E04.100.376.485', 'E04.650.410', 'E04.928.220.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07.541.510.738'], ['C14.280.484.660'], ['E04.936.664'], ['E04.936.864'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Influence of Land Use Change on Ecosystem Service Value Based on GEE in the Beijing-Tianjin-Hebei Region from 1998 to 2018]. | In sustainable development assessment of the Beijing-Tianjin-Hebei region, the ability to dynamically estimate the value of ecosystem services is of great significance. This study considers the Beijing-Tianjin-Hebei region as the research area, based on the google earth engine (GEE); the classification and decision tre... | ['Agriculture', 'Beijing', 'China', 'Conservation of Natural Resources', 'Ecosystem', 'Forests', 'Reproducibility of Results'] | 31,854,620 | [['J01.040'], ['Z01.252.474.164.225', 'Z01.433.114'], ['Z01.252.474.164'], ['J01.256', 'N06.230.080'], ['G16.500.275.157', 'N06.230.124'], ['G16.500.275.157.437', 'N06.230.124.343'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725']] | ['Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Ovarian estrogen receptor alpha and beta mRNA expression: impact of development and estrogen. | We tested the hypothesis that ERalpha and ERbeta mRNAs in the rat ovary are regulated during the post-natal period and in immature rats in response to estrogen treatment. Total ovarian ERbeta mRNA was more abundant than ERalpha mRNA and expression of ERbeta increased between post-natal days 4 and 12, coinciding with ad... | ['Animals', 'Base Sequence', 'Cell Differentiation', 'Cell Division', 'DNA Primers', 'Diethylstilbestrol', 'Down-Regulation', 'Estrogen Receptor alpha', 'Estrogen Receptor beta', 'Female', 'Gene Expression Regulation, Developmental', 'Granulosa Cells', 'In Situ Hybridization', 'Models, Biological', 'Ovary', 'RNA, Messe... | 10,375,027 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D02.455.426.559.389.150.700.725.500'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['D12.77... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Impact of exploratory offshore drilling on benthic communities in the Minerva gas field, Port Campbell, Australia. | Changes to benthic infauna caused by exploratory gas drilling operations in the Minerva field were examined experimentally using a BACI (before, after, control, impact) design. Analysis of 72 x 0.1 m2 Smith-McIntyre grab samples obtained from one pre-drilling and three post-drilling periods yielded a diverse fauna cons... | ['Animals', 'Australia', 'Environment', 'Gasoline', 'Geologic Sediments', 'Invertebrates', 'Water Pollutants, Chemical'] | 15,465,131 | [['B01.050'], ['Z01.639.100', 'Z01.678.100.373'], ['G16.500.275', 'N06.230'], ['D20.345.630.540', 'N06.230.132.258.630.540'], ['G01.311.330', 'G16.500.320'], ['B01.050.500'], ['D27.888.284.903.655']] | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Pectoralis major muscle flap in head and neck reconstruction. | Pectoralis major muscle flaps have rarely been used on their own for head and neck reconstruction. Some of the problems experienced with myocutaneous flaps can be avoided by the judicious use of muscle flaps. These include suture line separation, excessive bulk, hair growth from the flap, and alteration of breast posit... | ['Aged', 'Carcinoma, Squamous Cell', 'Combined Modality Therapy', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Male', 'Mandibular Neoplasms', 'Middle Aged', 'Paranasal Sinus Neoplasms', 'Pectoralis Muscles', 'Pharynx', 'Reoperation', 'Skin Neoplasms', 'Surgical Flaps', 'Tongue Neoplasms'] | 3,942,635 | [['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E02.186'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.149.721.450.583', 'C05.116.231.754.450.583', 'C05.500.499.583', 'C05.500.607.442', 'C07.320.515.583', 'C07.320.610.583'], ['M01.060.116.630'], ['C04.588.443.665.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Levels of leukotriene B4 in gingival crevicular fluid and gingival tissue in specific periodontal diseases. | BACKGROUND: Leukotriene B4 (LTB4), a product of the lipoxygenase pathway of arachidonic acid metabolism, exhibits numerous activities that can account for most of the features of host responses seen in periodontal diseases. The aim of the present study was to examine the role of LTB4 in the pathogenesis of specific per... | ['Adult', 'Aggressive Periodontitis', 'Case-Control Studies', 'Chromatography, High Pressure Liquid', 'Chronic Disease', 'Female', 'Gingiva', 'Gingival Crevicular Fluid', 'Gingivitis', 'Humans', 'Leukotriene B4', 'Male', 'Middle Aged', 'Periodontitis', 'Radioimmunoassay', 'Statistics, Nonparametric'] | 11,525,433 | [['M01.060.116'], ['C07.465.714.533.161'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.196.181.400.300'], ['C23.550.291.500'], ['A14.549.167.646.480'], ['A12.383.500'], ['C01.408', 'C07.465.714.258.480'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.251.355.255.100.450... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Surgical treatment for primary interdigital neuroma. | We studied 366 feet in 313 patients who underwent surgical treatment for a primary interdigital neuroma through a dorsal web-splitting incision. Three hundred five feet in 259 patients were available for follow up, which averaged 5.9 years (range: 2.8 to 13); 45.2% of these patients were completely satisfied, 33.8% wer... | ['Adult', 'Aged', 'Aged, 80 and over', 'Algorithms', 'Female', 'Foot Diseases', 'Humans', 'Male', 'Middle Aged', 'Neuroma', 'Soft Tissue Neoplasms'] | 1,866,348 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G17.035', 'L01.224.050'], ['C05.360', 'C17.800.321'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.557.580.600.610'], ['C04.588.839']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Electrical stimulation of the posterior and ventromedial hypothalamic nuclei causes specific activation of shivering and nonshivering thermogenesis. | Experiments were designed to determine in the same animal whether electrical stimulation of the posterior hypothalamus and ventromedial hypothalamic nucleus could specifically evoke shivering and nonshivering (brown adipose tissue) thermogenesis, respectively, in anesthetized, normothermic rats. Urethane-anesthetized, ... | ['Adipose Tissue, Brown', 'Animals', 'Body Temperature Regulation', 'Electric Stimulation', 'Electrodes, Implanted', 'Electromyography', 'Hypothalamus, Posterior', 'Male', 'Rats', 'Shivering', 'Ventromedial Hypothalamic Nucleus'] | 8,012,903 | [['A10.165.114.322'], ['B01.050'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['E05.723.402'], ['E07.305.250.319', 'E07.695.202'], ['E01.370.405.255', 'E01.370.530.255'], ['A08.186.211.180.497.362', 'A08.186.211.200.317.357.362'], ['B01.050.150.900.649.313.992.635.505.700'], ['G07.110.232.778.500', 'G07.410.421... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influenza A pandemics of the 20th century with special reference to 1918: virology, pathology and epidemiology. | Influenza A virus initiated worldwide epidemics (pandemics) in 1918, 1957, 1968 and 1977. A revised calculation of the 1918-1919 pandemic estimates that 40 million persons died and 500 million were infected. The mortalities in 1957 and 1968 were nearly 6 million. Biological and genetic characteristics of the causative ... | ['Alaska', 'Disease Outbreaks', 'France', 'History, 20th Century', 'Hong Kong', 'Humans', 'Influenza, Human', 'Norway', 'United Kingdom', 'United States'] | 10,713,598 | [['Z01.107.567.875.580.100'], ['N06.850.290'], ['Z01.542.286'], ['K01.400.504.968'], ['Z01.252.474.164.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.748.310', 'C01.925.782.620.365', 'C08.730.310'], ['Z01.542.816.374'], ['Z01.542.363'], ['Z01.107.567.875']] | ['Geographicals [Z]', 'Health Care [N]', 'Humanities [K]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Conventional allogeneic hematopoietic stem cell transplantation for lymphoma may overcome the poor prognosis associated with a positive FDG-PET scan before transplantation. | A positive scan in pretransplantation fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) has been shown to be associated with a poor prognosis in patients with lymphoma undergoing high-dose chemotherapy followed by autologous stem cell transplantation (ASCT). For those with a positive FDG-PET scan, t... | ['Adult', 'Female', 'Fluorodeoxyglucose F18', 'Follow-Up Studies', 'Hematopoietic Stem Cell Transplantation', 'Humans', 'Lymphoma', 'Male', 'Middle Aged', 'Positron-Emission Tomography', 'Prognosis', 'Retrospective Studies', 'Salvage Therapy', 'Transplantation, Homologous', 'Treatment Outcome'] | 18,266,206 | [['M01.060.116'], ['D09.254.229.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E02.095.147.500.500.500', 'E04.936.225.687.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386', 'C15.604.515.569', 'C20.683.515.761'], ['M01.060.116.630'], ['E01.370.350... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
CA 125 surveillance and second-look laparotomy in ovarian carcinoma. | CA 125 was evaluated as a tumor marker in 31 patients undergoing treatment for ovarian carcinoma, 17 of whom had second-look laparotomies. At the time of second-look laparotomy, 14 patients had CA 125 values in the normal range. Six of these patients had a positive second-look laparotomy. Although normal CA 125 values ... | ['Adult', 'Aged', 'Antigens, Neoplasm', 'Antigens, Surface', 'Antigens, Tumor-Associated, Carbohydrate', 'Carcinoma', 'Female', 'Follow-Up Studies', 'Humans', 'Laparotomy', 'Middle Aged', 'Ovarian Neoplasms', 'Reoperation'] | 3,456,202 | [['M01.060.116'], ['M01.060.116.100'], ['D23.050.285'], ['D23.050.301'], ['D23.050.285.050', 'D23.050.550.325', 'D23.101.140.075'], ['C04.557.470.200'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.406'], ['M01.060.116.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cholecystokinin octapeptide decreases intake of solid food in man. | Cholecystokinin octapeptide (CCK-OP) was reported to decrease the intake of liquid food in lean and in obese man. This study investigated the effect of CCK-OP on the consumption of real life food, i.e., of standardized sandwiches. Sixteen young non-obese females and males participated, after an overnight fast, each in ... | ['Adult', 'Appetite Depressants', 'Cholecystokinin', 'Clinical Trials as Topic', 'Double-Blind Method', 'Female', 'Humans', 'Hunger', 'Male', 'Peptide Fragments', 'Placebos', 'Sincalide'] | 6,285,318 | [['M01.060.116'], ['D27.505.954.203.155'], ['D06.472.317.152', 'D12.644.120'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658.293.391', 'G07.20... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Craniofacial pain secondary to occult head and neck tumors. | OBJECTIVES: To review the natural history of occult head and neck malignancy presenting with facial pain and evaluate the risk factors, diagnostic workup, and management of facial pain in the setting of occult malignancy.STUDY DESIGN: Retrospective chart review.SETTING: Tertiary care center.SUBJECTS AND METHODS: All pa... | ['Adult', 'Aged', 'Aged, 80 and over', 'Diagnostic Imaging', 'Facial Pain', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Male', 'Middle Aged', 'Pain Measurement', 'Retrospective Studies', 'Risk Factors'] | 24,486,779 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350'], ['C23.888.592.612.330'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.600.550.324'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Monitoring parenteral nutrition intraoperatively with the dextrometer. | Patients receiving parenteral nutrition support frequently undergo operative procedures. Proper selection of patients and close monitoring of glucose levels are crucial if parenteral nutrition is to be maintained intraoperatively. The Dextrometer was used in 10 patients receiving parenteral nutrition intraoperatively. ... | ['Aged', 'Blood Glucose', 'Female', 'Humans', 'Intraoperative Period', 'Male', 'Middle Aged', 'Monitoring, Physiologic', 'Parenteral Nutrition', 'Parenteral Nutrition, Total'] | 6,417,367 | [['M01.060.116.100'], ['D09.947.875.359.448.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374', 'N02.421.585.753.374'], ['M01.060.116.630'], ['E01.370.520'], ['E02.421.505', 'E02.642.500.505'], ['E02.421.505.575', 'E02.642.500.505.750']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Combining fMRI and DTI: a framework for exploring the limits of fMRI-guided DTI fiber tracking and for verifying DTI-based fiber tractography results. | A powerful, non-invasive technique for estimating and visualizing white matter tracts in the human brain in vivo is white matter fiber tractography that uses magnetic resonance diffusion tensor imaging. The success of this method depends strongly on the capability of the applied tracking algorithm and the quality of th... | ['Adult', 'Brain Mapping', 'Corpus Striatum', 'Evoked Potentials, Motor', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Motor Cortex', 'Nerve Fibers', 'Subtraction Technique'] | 17,931,889 | [['M01.060.116'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['A08.186.211.200.885.287.249.487'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.825.500'], [... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Investigation of chemomarkers of astragali radix of different ages and geographical origin by NMR profiling. | Astragalus roots from Astragalus membranaceus Bunge or Astragalus membranaceus var. mongholicus (Bunge) Hsiao are among the most popular traditional medicinal plants due to their diverse therapeutic uses based on their tonic, antinephritic, immunostimulant, hepatoprotectant, diuretic, antidiabetic, analgesic, expectora... | ['Astragalus propinquus', 'Isoflavones', 'Magnetic Resonance Spectroscopy', 'Metabolome', 'Metabolomics', 'Plant Roots', 'Saponins'] | 25,690,295 | [['B01.650.940.800.575.912.250.401.087.750'], ['D03.383.663.283.266.450.400', 'D03.633.100.150.266.450.400'], ['E05.196.867.519'], ['G03.500'], ['H01.158.201.586', 'H01.158.273.180.599', 'H01.181.122.638'], ['A18.400'], ['D09.408.782']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A(H1N1)v2009: a controlled observational prospective cohort study on vaccine safety in pregnancy. | BACKGROUND: A(H1N1)v2009 influenza vaccination of pregnant women was a challenge for health care providers, as little safety data were available.METHODS: We prospectively followed the pregnancies of women who were vaccinated at any time during pregnancy or ? 4 weeks prior to conception and compared these outcomes to a ... | ['Adolescent', 'Adult', 'Case-Control Studies', 'Female', 'Humans', 'Influenza A Virus, H1N1 Subtype', 'Influenza Vaccines', 'Middle Aged', 'Pregnancy', 'Pregnancy Outcome', 'Prospective Studies', 'Risk Factors', 'Vaccination', 'Young Adult'] | 22,564,554 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.405.400.214'], ['D20.215.894.899.302'], ['M01.060.116.630'], ['G08.686.784.769'], ['E01.789.700', 'G08.686.784.769.496'], ['E05.318.372.500... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Surgical treatment of congenital cysts of the liver]. | We report 9 patients who were surgically treated for symptomatic congenital liver cysts. Median age at presentation was 51 years and all the cases were females. Symptoms and clinical findings included a painful mass in the upper right quadrant of the abdomen. Ultrasonography was used most frequently and was an accurate... | ['Adult', 'Cysts', 'Female', 'Humans', 'Liver Diseases', 'Middle Aged'] | 8,962,776 | [['M01.060.116'], ['C04.182', 'C23.300.306'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552'], ['M01.060.116.630']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The ribokinases of Arabidopsis thaliana and Saccharomyces cerevisiae are required for ribose recycling from nucleotide catabolism, which in plants is not essential to survive prolonged dark stress. | Nucleotide catabolism in Arabidopsis thaliana and Saccharomyces cerevisiae leads to the release of ribose, which requires phosphorylation to ribose-5-phosphate mediated by ribokinase (RBSK). We aimed to characterize RBSK in plants and yeast, to quantify the contribution of plant nucleotide catabolism to the ribose pool... | ['Arabidopsis', 'Arabidopsis Proteins', 'Darkness', 'Nucleotides', 'Phosphotransferases (Alcohol Group Acceptor)', 'Phylogeny', 'Ribose', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Stress, Physiological'] | 28,921,561 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G01.590.540.233'], ['D09.408.620', 'D13.695'], ['D08.811.913.696.620'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D09.947.875.627.651'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12.776.354.750'], ['G07.775']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Prophylaxis with ciprofloxacin in transurethral surgery]. | The purpose of the study was to compare in a prospective randomized study the effect of three doses of prophylactic administration of ciprofloxacin in 25 patients and a control group of 26 patients without prophylactic antibiotic treatment in conjunction with transurethral surgery. In the group of patients with prophyl... | ['Aged', 'Ciprofloxacin', 'Humans', 'Male', 'Premedication', 'Prospective Studies', 'Prostate', 'Urethra', 'Urinary Bladder'] | 7,716,662 | [['M01.060.116.100'], ['D03.633.100.810.835.322.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.703'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['A05.360.444.575', 'A10.336.707'], ['A05.360.444.492.726', 'A05.810.876'], ['A05.810.890']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Decreased circulating endothelial progenitor cell levels and function in patients with nonalcoholic fatty liver disease. | OBJECTIVES: Nonalcoholic fatty liver disease (NAFLD) is associated with advanced atherosclerosis and a higher risk of cardiovascular disease. Increasing evidence suggests that injured endothelial monolayer is regenerated by circulating bone marrow derived-endothelial progenitor cells (EPCs), and levels of circulating E... | ['Aged', 'Aged, 80 and over', 'Atherosclerosis', 'Blood Cells', 'Cardiovascular Diseases', 'Case-Control Studies', 'Cell Count', 'Endothelial Cells', 'Fatty Liver', 'Female', 'Humans', 'Male', 'Middle Aged', 'Non-alcoholic Fatty Liver Disease', 'Risk Factors', 'Stem Cells'] | 22,359,630 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.137.126.307'], ['A11.118', 'A15.145.229'], ['C14'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A11.436.275'], ['C06.552.241'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Toxicity from modafinil ingestion. | INTRODUCTION: Modafanil, a non-amphetamine stimulant, is used for narcolepsy, sleep apnea, and shift work sleep disorder. There is little available information on the toxicity of modafinil overdose.METHOD: We performed a retrospective multi-poison center chart review of patients from 11 states who had a single substanc... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Benzhydryl Compounds', 'Central Nervous System Stimulants', 'Child', 'Child, Preschool', 'Drug Overdose', 'Female', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Modafinil', 'Neurotoxicity Syndromes', 'Poison Control Centers', 'Retrospective Studies', 'Tachycardia', '... | 18,787,992 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D02.455.426.559.389.115'], ['D27.505.696.282', 'D27.505.954.427.220'], ['M01.060.406'], ['M01.060.406.448'], ['C25.775.383', 'E02.319.306.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], [... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Assessment of a new strategy, based on Aedes aegypti (L.) pupal productivity, for the surveillance and control of dengue transmission in Thailand. | In the countries where the disease is endemic, control of dengue is mainly based on the elimination or treatment of the water-filled containers where the main vector, Aedes aegypti, breeds, in interventions usually reliant on community participation. Although such control activities must be continuous, since vector era... | ['Aedes', 'Animals', 'Dengue', 'Endemic Diseases', 'Female', 'Humans', 'Male', 'Population Surveillance', 'Pupa', 'Rural Health', 'Seasons', 'Thailand', 'Urban Health', 'Water', 'Water Supply'] | 18,318,938 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['C01.920.500.270', 'C01.925.081.270', 'C01.925.782.350.250.214', 'C01.925.782.417.214'], ['N06.850.392'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980.438.700', 'N05.715.360.300.800.438.625', 'N06.850.520.308.980.438.700', 'N0... | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Antidiarrhoeal activity of eriosematin E isolated from the roots of Eriosema chinense Vogel. | BACKGROUND: Roots of the plant Eriosema chinense Vogel (Fabaceae) is distributed mainly over the Eastern Himalayan region of India and China. The roots of the plant are used as a vegetable by the people of Northern Australia, China and North East India and are used traditionally by the tribal people of Meghalaya (India... | ['Animals', 'Antidiarrheals', 'Diarrhea', 'Fabaceae', 'Flavanones', 'India', 'Intestines', 'Male', 'Phytotherapy', 'Plant Extracts', 'Plant Roots', 'Plants, Medicinal', 'Rats'] | 28,160,852 | [['B01.050'], ['D27.505.954.483.161'], ['C23.888.821.214'], ['B01.650.940.800.575.912.250.401'], ['D03.383.663.283.266.450.252', 'D03.633.100.150.266.450.252'], ['Z01.252.245.393'], ['A03.556.124'], ['E02.190.755'], ['D20.215.784.500', 'D26.667'], ['A18.400'], ['B01.650.560'], ['B01.050.150.900.649.313.992.635.505.700'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
A cohort study on mortality of "yusho" patients: a preliminary report. | In 1968, a mass food poisoning (yusho) occurred in western Japan involving more than 1,850 people, the majority of whom were residents of Fukuoka and Nagasaki prefectures. The poisoning is now understood to have been caused by ingestion of a commercial brand of rice oil contaminated with polychlorinated derivatives of ... | ['Cohort Studies', 'Dietary Fats', 'Food Contamination', 'Foodborne Diseases', 'Humans', 'Japan', 'Male', 'Neoplasms', 'Oryza', 'Polychlorinated Biphenyls'] | 3,147,283 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D10.212.302', 'G07.203.300.375', 'J02.500.375'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['C25.723.415'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['C04'], ['B... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
The phenotypes of podocytes and parietal epithelial cells may overlap in diabetic nephropathy. | Reversal of diabetic nephropathy (DN) has been achieved in humans and mice, but only rarely and under special circumstances. As progression of DN is related to podocyte loss, reversal of DN requires restoration of podocytes. Here, we identified and quantified potential glomerular progenitor cells that could be a source... | ['Bowman Capsule', 'Cell Plasticity', 'Cell Proliferation', 'Claudin-1', 'Cyclin-Dependent Kinase Inhibitor p57', 'Diabetic Nephropathies', 'Epithelial Cells', 'Humans', 'Ki-67 Antigen', 'Kidney Glomerulus', 'Microfilament Proteins', 'Phenotype', 'Podocytes', 'Regeneration', 'Retrospective Studies', 'Stem Cells', 'WT1 ... | 26,376,129 | [['A05.810.453.736.560.254'], ['G04.356.250'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.776.543.940.200.100'], ['D12.644.360.225.700', 'D12.776.167.187.700', 'D12.776.476.225.700', 'D12.776.624.776.355.700'], ['C12.777.419.192', 'C13.351.968.419.192', 'C19.246.099.875'], ['A11.436'], ['B01.050.150.900.649.313.988.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Analysis of melanoma cell type in uveal melanoma following treatment failure. | PURPOSE: To determine whether an increase (or progression) in the degree of malignancy according to cytologic or histopathologic criteria corresponded with failure of intraocular melanoma control.DESIGN: Retrospective case control study from a single institution.METHODS: Uveal melanoma patients had either fine-needle a... | ['Biopsy, Needle', 'Brachytherapy', 'Case-Control Studies', 'Eye Enucleation', 'Humans', 'Iodine Radioisotopes', 'Melanoma', 'Retrospective Studies', 'Treatment Failure', 'Uveal Neoplasms'] | 15,488,778 | [['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['E02.815.150'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E04.540.429'], ['B01.050.150.900.64... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Salt stress affects xylem differentiation of grey poplar (Populus x canescens). | In this study the impact of salt stress on the physiology and wood structure of the salt-sensitive Populus x canescens was investigated. Two weeks of salt stress altered wood anatomy significantly. The xylem differentiation zone was reduced and the resulting vessels exhibited reduced lumina. To understand this phenomen... | ['Abscisic Acid', 'Arabidopsis', 'Biological Transport', 'Cell Differentiation', 'Crosses, Genetic', 'Elements', 'Gene Expression Regulation, Plant', 'Malates', 'Phylogeny', 'Plant Leaves', 'Plant Roots', 'Populus', 'Potassium', 'Potassium Channels', 'RNA, Messenger', 'Sodium', 'Sodium Chloride', 'Stress, Physiological... | 18,946,679 | [['D02.241.223.268.034', 'D02.455.326.271.665.202.061', 'D02.455.426.392.368.367.379.249.024', 'D02.455.849.131.061', 'D02.455.849.765.521.500'], ['B01.650.940.800.575.912.250.157.100'], ['G03.143'], ['G04.152'], ['E05.393.281'], ['D01.268'], ['G05.308.375'], ['D02.241.081.337.463', 'D02.241.511.505'], ['G05.697', 'G16... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Identification of major dioxin-like compounds and androgen receptor antagonist in acid-treated tissue extracts of high trophic-level animals. | We evaluated the applicability of combining in vitro bioassays with instrument analyses to identify potential endocrine disrupting pollutants in sulfuric acid-treated extracts of liver and/or blubber of high trophic-level animals. Dioxin-like and androgen receptor (AR) antagonistic activities were observed in Baikal se... | ['Androgen Receptor Antagonists', 'Animals', 'Dioxins', 'Humans', 'Peroxisome Proliferator-Activated Receptors', 'Porpoises', 'Raccoon Dogs', 'Rats', 'Receptors, Androgen', 'Receptors, Estrogen', 'Receptors, Glucocorticoid', 'Seals, Earless', 'Water Pollutants, Chemical'] | 22,003,927 | [['D06.347.065.249', 'D27.505.696.399.450.065.249'], ['B01.050'], ['D02.309.500', 'D03.383.231'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.826.239', 'D12.776.930.705'], ['B01.050.150.900.649.313.875.566'], ['B01.050.150.900.649.313.750.250.216.700'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.... | ['Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
HLA-DM and MHC class II molecules co-distribute with peptidase-containing lysosomal subcompartments. | MHC class II molecules associate with peptides in the endocytic pathway. Different endosomal locations for peptide loading of class II molecules, varying from early endosomes (EE) to lysosomes, have been assigned on the basis of subcellular fractionation experiments. We have determined the intracellular location of HLA... | ['Cathepsin D', 'Cell Fractionation', 'Endopeptidases', 'HLA-D Antigens', 'Histocompatibility Antigens Class II', 'Humans', 'Lysosomes', 'Tumor Cells, Cultured', 'beta-N-Acetylhexosaminidases'] | 8,671,650 | [['D08.811.277.656.074.500.180', 'D08.811.277.656.224.187', 'D08.811.277.656.300.048.180'], ['E05.242.251'], ['D08.811.277.656.300'], ['D12.776.395.550.509.400', 'D12.776.543.550.440.400', 'D23.050.301.500.400.400', 'D23.050.301.500.450.400', 'D23.050.705.552.410.400', 'D23.050.705.552.450.400'], ['D12.776.395.550.509'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cytotoxic steroidal glycosides from Allium flavum. | Three new spirostane-type glycosides (1-3) were isolated from the whole plant of Allium flavum. Their structures were elucidated mainly by 2D NMR spectroscopic analysis and mass spectrometry as (20S,25R)-2á-hydroxyspirost-5-en-3â-yl O-â-D-xylopyranosyl-(1?3)-[â-D-galactopyranosyl-(1?2)]-â-D-galactopyranosyl-(1?4)-â-D-g... | ['Allium', 'Antineoplastic Agents, Phytogenic', 'Cell Line, Tumor', 'Drug Screening Assays, Antitumor', 'Glycosides', 'Humans', 'Magnetic Resonance Spectroscopy', 'Mass Spectrometry', 'Molecular Structure', 'Phytosterols'] | 24,380,693 | [['B01.650.940.800.575.912.250.618.100.050.060'], ['D27.505.954.248.179'], ['A11.251.210.190', 'A11.251.860.180'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['D09.408'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.867.519'], ['E05.196.566'], ['G02.111.570', 'G02.466'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Obesity genes and gene-environment-behavior interactions: recommendations for a way forward. | Obesity is a classical complex trait, influenced by both genetic and lifestyle factors. The number of obesity gene variants is currently unknown but, based on sound evolutionary principles, likely to be many, each with a modest effect on the phenotype. Recent advances in our knowledge of variation in the human genome a... | ['Environment', 'Feeding Behavior', 'Genetic Predisposition to Disease', 'Genetic Variation', 'Genome-Wide Association Study', 'Humans', 'Obesity', 'Polymorphism, Single Nucleotide'] | 19,037,219 | [['G16.500.275', 'N06.230'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.365'], ['E05.318.370.392', 'E05.318.416.249', 'E05.393.385.500', 'E05.393.522.500', 'E05.393.760.640.500', 'N06.850.520.445.392', 'N06.850.520.470.500'], ['B01.050.150.900.649.313.988.400.11... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Mucinous metaplasia of apocrine duct. | Mucinous syringometaplasia is a rare condition characterized by the presence of mucinous cells lining eccrine ducts. Because most occurrences are on the palms and soles, the disorder is generally considered to be the result of chronic trauma or pressure. We describe an example of mucinous metaplasia involving an apocri... | ['Adenoma, Sweat Gland', 'Apocrine Glands', 'Diagnosis, Differential', 'Female', 'Humans', 'Metaplasia', 'Middle Aged', 'Neoplasms, Adnexal and Skin Appendage'] | 9,580,527 | [['C04.557.470.035.175', 'C04.557.470.550.175'], ['A10.336.899.206', 'A17.815.830.206'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.589'], ['M01.060.116.630'], ['C04.557.470.550']] | ['Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fasudil, an inhibitor of Rho-associated coiled-coil kinase, attenuates hyperoxia-induced pulmonary fibrosis in neonatal rats. | BACKGROUND: Oxygen therapy is important during the management of high-risk neonatal infants, such as those with preterm birth, low birth weight, and asphyxia. However, prolonged exposure to high oxygen concentrations can readily lead to diffuse nonspecific inflammation, which promotes airway remodeling and pulmonary fi... | ['1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine', 'Animals', 'Animals, Newborn', 'Blotting, Western', 'Disease Models, Animal', 'Female', 'Hyperoxia', 'Immunohistochemistry', 'Male', 'Protein Kinase Inhibitors', 'Pulmonary Fibrosis', 'Rats', 'Rats, Sprague-Dawley', 'rho-Associated Kinases'] | 26,722,398 | [['D02.886.590.700.545', 'D03.383.606.527', 'D03.633.100.531.400'], ['B01.050'], ['B01.050.050.282'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.888.852.567'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Circumscribed scleroderma combined with lichen sclerosus et atrophicus]. | We report on two patients suffering from circumscribed scleroderma as well as lichen sclerosus et atrophicus. The cases are remarkable because it was possible to demonstrate histopathologic markers of both conditions in the same specimen. | ['Adult', 'Female', 'Humans', 'Middle Aged', 'Scleroderma, Localized', 'Skin', 'Skin Diseases'] | 3,984,437 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C17.300.787', 'C17.800.767'], ['A17.815'], ['C17.800']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Effectiveness of an intervention in schools to increase vaccination coverage in children aged 6]. | The management of the vaccination program is part of nursing competences. The main goal of this program is to vaccinate the whole population. There are some age groups in which vaccination coverage is represented by very low rates. Several methods can be used in order to increase such coverage and each professional sha... | ['Child', 'Humans', 'School Health Services', 'Spain', 'Vaccination'] | 21,428,006 | [['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.726.809'], ['Z01.542.846'], ['E02.095.465.425.400.530.890', 'E05.478.550.600.890', 'N02.421.726.758.310.890', 'N06.850.780.200.425.900', 'N06.850.780.680.310.890']] | ['Named Groups [M]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Synthesizing Qualitative Data Sets to Improve the Design of Trials and Complex Health Interventions: A Worked Example. | Qualitative researchers are increasingly reanalyzing and synthesizing data sets from different studies, and this method has now been used across trials to inform trial methodology and delivery. Despite this work, however, limited guidance exists about how this method should be employed. This article details an example ... | ['Data Analysis', 'Depression', 'Humans', 'Interviews as Topic', 'Qualitative Research', 'Randomized Controlled Trials as Topic', 'Research Design', 'United Kingdom'] | 30,293,516 | [['H01.548.338'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['H01.770.644.241.850'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365.500'], ['E05.581.500', 'H... | ['Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
[Comparison of chemical compositions in Moutan Cortex, Paeoniae Rubra Radix and Paeoniae Alba Radix based on "component structure" theory]. | To analyze and compare the chemical compositions of Moutan Cortex, Paeoniae Rubra Radix and Paeoniae Alba Radix based on "component structure" theory. Thirteen batches of Moutan Cortex, 14 batches of Paeoniae Rubra Radix from different origins and 10 batches of Paeoniae Alba Radix from different origins were analyzed b... | ['Chromatography, High Pressure Liquid', 'Drugs, Chinese Herbal', 'Paeonia', 'Principal Component Analysis'] | 28,895,329 | [['E05.196.181.400.300'], ['D20.215.784.500.350', 'D26.335'], ['B01.650.940.800.575.912.250.791'], ['E05.318.740.562']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bonding of resin cements to a metal substrate: influence of pretreatment on the adherence energy. | The adherence of resin cements to restoration as well as tooth structure is of prime importance for the longevity of cemented restorations. It was the aim of the study to investigate the effect of an acid and a base primer on (i) surface polarity of a nonprecious alloy and on (ii) adherence energy of resin cements bond... | ['Adhesiveness', 'Analysis of Variance', 'Chromium Alloys', 'Dental Bonding', 'Kinetics', 'Maleates', 'Materials Testing', 'Resin Cements', 'Solvents', 'Surface Properties', 'Thermodynamics', 'Toluidines', 'Wettability'] | 9,021,331 | [['G02.860.139'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D01.220.175', 'D01.552.033.182', 'D25.058.224', 'D25.339.208.224', 'J01.637.051.058.224', 'J01.637.051.339.208.224'], ['E06.095'], ['G01.374.661', 'G02.111.490'], ['D02.241.081.337.502'], ['E05.570'], ['D05.750.716.822.730', 'D25.339... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Categories of depression: reported life events in a controlled design. | In a case control study, 32 onset cases of depression, separated into PSE-CATEGO Categories N and R, were compared with individually matched symptom free general practice attenders. Combining both categories of depressives together a significantly greater number reported an Undesirable Life Event and a Threatening Life... | ['Adolescent', 'Adult', 'Depressive Disorder', 'Female', 'Humans', 'Life Change Events', 'Male', 'Middle Aged', 'Occupations', 'Time Factors'] | 3,830,325 | [['M01.060.057'], ['M01.060.116'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458.410'], ['M01.060.116.630'], ['N01.824.547'], ['G01.910.857']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Assessment in general practice: the predictive value of written-knowledge tests and a multiple-station examination for actual medical performance in daily practice. | This study compares the predictive values of written-knowledge tests and a standardized multiple-station examination for the actual medical performance of general practitioners (GPs) in order to select effective assessment methods to be used in quality-improvement activities. A comprehensive assessment was performed in... | ['Clinical Competence', 'Education, Medical, Continuing', 'Family Practice', 'Humans'] | 10,211,240 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.358.212.350', 'I02.358.399.250'], ['H02.403.340.500'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Ultrasensitive SERS Substrate for Label-Free Therapeutic-Drug Monitoring of Paclitaxel and Cyclophosphamide in Blood Serum. | Surface-enhanced Raman spectroscopy (SERS) has recently emerged as an innovative tool for therapeutic-drug monitoring (TDM), making it an ideal candidate for personalized treatment. Herein, we report a layer-by-layer (LbL) approach for the fabrication of a highly reproducible hybrid SERS substrate based on graphene oxi... | ['Animals', 'Biosensing Techniques', 'Cattle', 'Cyclophosphamide', 'Drug Monitoring', 'Gold', 'Graphite', 'Humans', 'Metal Nanoparticles', 'Paclitaxel', 'Quinolines', 'Serum Albumin, Bovine', 'Spectrum Analysis, Raman'] | 30,580,508 | [['B01.050'], ['E05.601.043'], ['B01.050.150.900.649.313.500.380.271'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['E01.370.520.200'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['D01.268.150.300', 'D01.578.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.637.512.600.500'], ['... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Rickets associated with vitamin D deficiency in young sheep. | An outbreak of rickets in sheep under a year old (hoggs) appeared clinically as stiffness and rotation of the carpal joints. Histological studies confirmed the diagnosis and biochemical analyses of blood demonstrated a primary vitamin D deficiency. | ['Animals', 'Disease Outbreaks', 'Female', 'Growth Plate', 'Male', 'Rickets', 'Scotland', 'Sheep', 'Sheep Diseases', 'Vitamin D', 'Vitamin D Deficiency'] | 3,394,220 | [['B01.050'], ['N06.850.290'], ['A02.835.232.251.352'], ['C05.116.198.816', 'C18.452.104.816', 'C18.452.174.845', 'C18.654.521.500.133.770.734'], ['Z01.542.363.766'], ['B01.050.150.900.649.313.500.380.791'], ['C22.836'], ['D04.210.500.812.768'], ['C18.654.521.500.133.770']] | ['Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Diseases [C]', 'Geographicals [Z]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Nocebo Effect in Meni?re's Disease: A Meta-analysis of Placebo-controlled Randomized Controlled Trials. | OBJECTIVE: To estimate the frequency and strength of nocebo effects in trials for Meni?re disease (MD).DATA SOURCES: A literature search was conducted in PUBMED. The search terms we used were " Meni?re or Meni?re's," "treatment," and "placebo." Limitations included article type to be Clinical Trial or Randomized Contro... | ['Humans', 'Meniere Disease', 'Nocebo Effect', 'Randomized Controlled Trials as Topic', 'Treatment Outcome'] | 28,832,394 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C09.218.568.217.500'], ['N05.715.350.350.625.500', 'N06.850.490.734.875.500'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365.500'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Repopulation of laser-perforated chondroepiphyseal matrix with xenogeneic chondrocytes. An experimental model. | Growth of chondrocytes into a xenogeneic chondroepiphyseal matrix was investigated in an in vitro experimental model by combining viable calf chondrocytes with chick epiphyseal matrix devoid of viable chondrocytes. The chondrocytes were harvested from the wrist joints of newborn calves and cultured for 2 days. The epip... | ['Animals', 'Bone Matrix', 'Cartilage, Articular', 'Cell Division', 'Cell Survival', 'Cell Transplantation', 'Chick Embryo', 'Coculture Techniques', 'Epiphyses', 'Microscopy, Fluorescence', 'Transplantation, Heterologous'] | 8,618,151 | [['B01.050'], ['A10.165.265.166'], ['A02.165.407.150', 'A02.835.583.192'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.346'], ['E02.095.147.500', 'E04.936.225'], ['A13.350.150', 'A16.331.200'], ['E05.481.500.374'], ['A02.835.232.251'], ['E01.370.350.515.458', 'E05.595.458'], ['E04.93... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Overreplication and recombination of DNA in higher eukaryotes: potential consequences and biological implications. | We propose that a fundamental problem in the faithful replication of complex chromosomes of higher eukaryotes is the proper control of both the number and timing of the multiple initiations of replication on single chromosomes. When replication patterns are disrupted by any of a variety of agents, overreplication of DN... | ['Aging', 'Biological Evolution', 'Cell Cycle', 'Cell Physiological Phenomena', 'Chromosome Aberrations', 'DNA Replication', 'Eukaryotic Cells', 'Extrachromosomal Inheritance', 'Gene Amplification', 'Neoplasms', 'Recombination, Genetic', 'Sister Chromatid Exchange'] | 3,457,380 | [['G07.345.124'], ['G05.045', 'G16.075'], ['G04.144'], ['G04'], ['C23.550.210', 'G05.365.590.175'], ['G02.111.225', 'G05.226'], ['A11.450'], ['G05.420.275'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['C04'], ['G05.728'], ['G05.728.615.750']] | ['Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Karyotypic similarity identifies multiple host-shifts of a pathogenic fungus in natural populations. | The detection of incipient host-shifts is important to the study of emergent diseases because it allows the examination of ecological and genetic conditions that favor novel inter-species transmission. Mixed populations of Silene latifolia and Silene vulgaris were investigated for the putative occurrence of host-shifts... | ['Basidiomycota', 'Electrophoresis', 'Genes, Fungal', 'Genetics, Population', 'Humans', 'Karyotyping', 'Phylogeny', 'Silene'] | 12,797,978 | [['B01.300.179'], ['E05.196.401', 'E05.301.300'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['H01.158.273.343.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['G05.697', 'G16.07... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
The implementation of overdose prevention sites as a novel and nimble response during an illegal drug overdose public health emergency. | BACKGROUND: Drug-related overdoses were declared a public health emergency in British Columbia, Canada in April, 2016 facilitating the scale-up of responses including rapid sanctioning and implementation of overdose prevention sites (OPSs). OPSs are a health service providing supervised injection and immediate overdose... | ['Adult', 'British Columbia', 'Drug Overdose', 'Emergencies', 'Female', 'Humans', 'Illicit Drugs', 'Male', 'Middle Aged', 'Needle-Exchange Programs', 'Public Health', 'Substance Abuse, Intravenous', 'Young Adult'] | 30,708,237 | [['M01.060.116'], ['Z01.107.567.176.160'], ['C25.775.383', 'E02.319.306.500.500'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.878'], ['M01.060.116.630'], ['N02.421.726.708'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['C25.775.793', 'F03.900.793'], ['M... | ['Named Groups [M]', 'Geographicals [Z]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Inhibition of in vitro natural killer activity by the third component of complement: role for the C3a fragment. | Purified human native third component of complement, C3, was found to inhibit in vitro natural killer (NK) cell cytotoxicity in both mouse and human systems. The effect was dose and time dependent, a 50% inhibition being reached with 190 nM C3 (35 micrograms/ml) added during the NK assay or after a 30-min preincubation... | ['Animals', 'Cell Line', 'Complement C3', 'Complement C3a', 'Cytotoxicity, Immunologic', 'Humans', 'Killer Cells, Natural', 'Kinetics', 'Leukemia, Experimental', 'Leukemia, Myeloid, Acute', 'Male', 'Mice', 'Mice, Nude', 'Spleen'] | 6,985,269 | [['B01.050'], ['A11.251.210'], ['D12.776.124.050.140', 'D12.776.124.486.274.250'], ['D12.776.124.486.274.024.250', 'D12.776.124.486.274.250.250'], ['G12.287'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.555.567.537', 'A15.145.229.637.555.567.537', 'A15.382.490.555.567.537'], ['G01.374.661', 'G02.111... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification and characterization of a conserved, stage-specific gene product of Plasmodium falciparum recognized by parasite growth inhibitory antibodies. | We have identified a novel conserved protein of Plasmodium falciparum, designated D13, that is stage-specifically expressed in asexual blood stages of the parasite. The predicted open reading frame (ORF) D13 contains 863 amino acids with a calculated molecular mass of 99.7 kDa and displays a repeat region composed of p... | ['Amino Acid Sequence', 'Animals', 'Antibodies, Monoclonal', 'Antibodies, Protozoan', 'Erythrocytes', 'Humans', 'Life Cycle Stages', 'Malaria, Falciparum', 'Mice', 'Molecular Sequence Data', 'Open Reading Frames', 'Plasmodium falciparum', 'Protozoan Proteins', 'Sequence Analysis, DNA'] | 12,654,839 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.050.150.900.649... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Portosystemic encephalopathy and splanchnic hemodynamics in liver cirrhosis]. | In 166 patients with liver cirrhosis (LC) and the portal hypertension syndrome the complex hemodynamical investigations were performed. It was established that portosystemic encephalopathy (PSE) is caused by the portosystemic shunts occurrence resulting in lowering of the volumetric blood flow in portal vein and hepati... | ['Adult', 'Hepatic Encephalopathy', 'Humans', 'Hypertension, Portal', 'Liver', 'Liver Cirrhosis', 'Middle Aged', 'Retrospective Studies'] | 10,330,833 | [['M01.060.116'], ['C06.552.308.500.356', 'C10.228.140.163.360', 'C18.452.132.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.494'], ['A03.620'], ['C06.552.630', 'C23.550.355.412'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cultural adaptation among Hispanic women as related to awareness and acquisition of emergency contraception. | BACKGROUND: The study was conducted to examine the relationship between cultural adaptation (acculturation), contraceptive use, personal history of induced abortion, and emergency contraceptive (EC) awareness and acquisition among a sample of young sexually active Hispanic women.STUDY DESIGN: A total of 959 Hispanic wo... | ['Abortion, Induced', 'Acculturation', 'Adolescent', 'Contraception Behavior', 'Contraception, Postcoital', 'Contraceptive Agents, Female', 'Female', 'Health Care Surveys', 'Health Knowledge, Attitudes, Practice', 'Hispanic Americans', 'Humans', 'Income', 'Texas', 'Young Adult'] | 21,074,016 | [['E04.520.050'], ['I01.076.201.450.050', 'I01.880.853.100.079'], ['M01.060.057'], ['F01.145.688.500', 'G08.686.784.891.500'], ['E02.875.194.540'], ['D27.505.696.875.360.276', 'D27.505.954.705.360.276'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['F... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
An integrated analysis of differential miRNA and mRNA expressions in human gallstones. | Gallstone disease, including cholesterol precipitation in bile, increased bile salt hydrophobicity and gallbladder inflammation. Here, we investigated miRNA and mRNA involved in the formation of gallstones, and explored the molecular mechanisms in the development of gallstones. Differentially expressed 17 miRNAs and 52... | ['ATP-Binding Cassette Transporters', 'Cells, Cultured', 'Databases, Protein', 'Gallbladder', 'Gallstones', 'Gene Expression Profiling', 'Gene Regulatory Networks', 'Humans', 'MicroRNAs', 'RNA, Messenger', 'Real-Time Polymerase Chain Reaction', 'Reproducibility of Results'] | 25,639,987 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['A11.251'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['A03.159.439'], ['C06.130.409.633', 'C06.130.564.332.500', 'C23.300.175.525']... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Information Science [L]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Pressurized whey protein can limit bacterial burden and protein oxidation in Pseudomonas aeruginosa lung infection. | BACKGROUND: Lung infection caused by Pseudomonas aeruginosa is associated with an exuberant inflammatory response, oxidative stress, and lung damage. Whey protein is a rich source of cysteine, and anti-inflammatory and immune-enhancing peptides. Anti-inflammatory and antioxidant properties of whey are augmented by hype... | ['Animals', 'Anti-Inflammatory Agents', 'Antioxidants', 'Bronchoalveolar Lavage', 'Cysteine', 'Dietary Supplements', 'Disease Models, Animal', 'Female', 'Glutathione', 'Lipid Peroxidation', 'Lung', 'Mice', 'Mice, Inbred C57BL', 'Milk Proteins', 'Oxidative Stress', 'Pseudomonas Infections', 'Pseudomonas aeruginosa', 'We... | 23,395,602 | [['B01.050'], ['D27.505.954.158'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['E05.927.100'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['G07.203.300.456', 'J02.500.456'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.644.456.448'], ['G02.111.515', 'G03.29... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Observation of Corneal Langerhans Cells by In Vivo Confocal Microscopy in Thyroid-Associated Ophthalmopathy. | PURPOSE: To examine the density and morphology of Langerhans cells (LCs) in the cornea of patients with thyroid-associated ophthalmopathy (TAO).METHODS: Forty patients with TAO and 20 healthy volunteers were studied. All subjects underwent a thorough ophthalmic examination of both eyes. The ocular surface status was as... | ['Adult', 'Cell Count', 'Cornea', 'Female', 'Follow-Up Studies', 'Graves Ophthalmopathy', 'Healthy Volunteers', 'Humans', 'Langerhans Cells', 'Male', 'Microscopy, Confocal', 'Middle Aged', 'Reproducibility of Results', 'Retrospective Studies', 'Severity of Illness Index'] | 26,735,162 | [['M01.060.116'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A09.371.060.217'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C11.270.240', 'C11.675.349.500.500', 'C16.320.347', 'C19.874.283.605.500', 'C19.874.397.370.500', 'C20.111.555.500'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Multiple brain metastasis from renal cell carcinoma--a care report]. | A 51-year-old woman was admitted with left renal cancer with lung metastasis. Nephrectomy was performed in September 1976. She was readmitted in comatous state 2.3 years later. Excision of multiple brain metastases resulted in recovery of consciousness and she was able to resume her normal life. However, 6 months later... | ['Adenocarcinoma', 'Brain Neoplasms', 'Female', 'Humans', 'Kidney Neoplasms', 'Lung Neoplasms', 'Middle Aged'] | 6,887,528 | [['C04.557.470.200.025'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.947.535', 'C12.758.820.750', 'C12.777.419.473', 'C13.351.937.820.535', 'C13.351.968.419.473'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Breast radiography using the oblique projection. | For 3,058 consecutive women who underwent film-screen mammography, oblique, mediolateral, and cephalocaudal images were obtained. Eighty neoplasms were identified. The oblique view disclosed all but one of the cancers; for six patients, it was the only projection that depicted a lesion in the upper-outer quadrant of th... | ['Adult', 'Aged', 'Breast Neoplasms', 'Female', 'Humans', 'Male', 'Mammography', 'Middle Aged'] | 6,622,708 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['M01.060.116.630']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Immunohistochemical expression of fibroblast growth factor (FGF)-2 in epilepsy-associated malformations of cortical development (MCDs). | To elucidate the biological significance of dysplastic cells in malformations of cortical development, an immunohistochemical study was performed to investigate fibroblast growth factor-2 (FGF-2) expression in corticectomy specimens from epilepsy patients, including focal cortical dysplasia (FCD) with balloon cells (BC... | ['Adolescent', 'Adult', 'Astrocytes', 'Basic Helix-Loop-Helix Transcription Factors', 'Cerebral Cortex', 'Child', 'Child, Preschool', 'Epilepsy', 'Female', 'Fibroblast Growth Factor 2', 'Humans', 'Immunohistochemistry', 'Infant', 'Male', 'Malformations of Cortical Development', 'Middle Aged', 'Nerve Tissue Proteins', '... | 18,179,408 | [['M01.060.057'], ['M01.060.116'], ['A08.637.200', 'A11.650.200'], ['D12.776.260.103', 'D12.776.930.125'], ['A08.186.211.200.885.287.500'], ['M01.060.406'], ['M01.060.406.448'], ['C10.228.140.490'], ['D12.644.276.624.120', 'D12.776.467.624.120', 'D23.529.624.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
[Diagnosis and classification of hematologic tumors using anti-lymphocyte monoclonal antibodies]. | Many hybridoma monoclonal antibodies to lymphocytes of T cell and B cell lineage and of both T and B cell lineage and stem cells were newly developed and characterized. Lymphocyte surface antigens that appear at the specific stages of T and B cell differentiation were clearly detected by these monoclonal antibodies. Th... | ['Antibodies, Monoclonal', 'Antigens, Neoplasm', 'Antigens, Surface', 'B-Lymphocytes', 'Humans', 'Leukemia', 'Lymphocyte Activation', 'Lymphoma', 'T-Lymphocytes'] | 6,603,817 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.285'], ['D23.050.301'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337'], ['E... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Structure and properties of G84R and L99M mutants of human small heat shock protein HspB1 correlating with motor neuropathy. | Some properties of G84R and L99M mutants of HspB1 associated with peripheral distal neuropathies were investigated. Homooligomers formed by these mutants are larger than those of the wild type HspB1. Large oligomers of G84R and L99M mutants have compromised stability and tend to dissociate at low protein concentration.... | ['Amino Acid Sequence', 'Dimerization', 'HSP20 Heat-Shock Proteins', 'HSP27 Heat-Shock Proteins', 'Heat-Shock Proteins', 'Humans', 'Molecular Chaperones', 'Molecular Sequence Data', 'Motor Neurons', 'Mutation', 'Nervous System Diseases', 'Phosphorylation', 'Point Mutation', 'Protein Binding', 'Protein Structure, Tertia... | 23,948,568 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.206', 'G03.230'], ['D12.776.580.216.270.500'], ['D12.776.580.216.270.625'], ['D12.776.580.216'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.580'], ['L01.453.245.667'], ['A08.675.655.500', 'A11.671.655.500'], ['G05.365.590'], ['C10'], ['G02.111.665', 'G0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Large numbers of primitive stem cells are active simultaneously in aggregated embryo chimeric mice. | The possibility has been repeatedly raised that erythropoiesis results from clonal succession--the differentiation of one or a very small number of the most primitive stem cells that are sequentially activated to proliferate forming clones of differentiated cells and then eventually decline, to be replaced by new stem ... | ['Animals', 'Cell Differentiation', 'Cell Division', 'Cell Survival', 'Chimera', 'Clone Cells', 'Erythropoiesis', 'Hematopoietic Stem Cells', 'Hemoglobins', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred CBA', 'Reticulocytes'] | 3,814,815 | [['B01.050'], ['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['G04.346'], ['B05.200'], ['A11.251.353'], ['G04.152.825.414', 'G09.188.343.414'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.992.635.505.500... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A light-regulated genetic module was recruited to carpel development in Arabidopsis following a structural change to SPATULA. | A key innovation of flowering plants is the female reproductive organ, the carpel. Here, we show that a mechanism that regulates carpel margin development in the model flowering plant Arabidopsis thaliana was recruited from light-regulated processes. This recruitment followed the loss from the basic helix-loop-helix tr... | ['Amino Acid Sequence', 'Arabidopsis', 'Arabidopsis Proteins', 'Base Sequence', 'Basic Helix-Loop-Helix Transcription Factors', 'Evolution, Molecular', 'Flowers', 'Gene Expression Regulation, Developmental', 'Gene Expression Regulation, Plant', 'Light', 'Models, Molecular', 'Molecular Sequence Data', 'Mutation', 'Nucle... | 22,851,763 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.260.103', 'D12.776.930.125'], ['G05.045.250', 'G16.075.250'], ['A18.024.249.500'], ['G05.308.310'], ['G05.308.375'], ['G01.358.500.505.650', 'G0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Life without DNA repair]. | BACKGROUND: Faithful maintenance of the genomic information is crucial for the survival of a species. Consequently, DNA repair processes must have evolved early during evolution. DNA damage left unrepaired might cause mutations leading to cell death, increased cancer incidence and severe syndromes.MATERIAL AND METHODS:... | ['Animals', 'Ataxia Telangiectasia', 'Base Pair Mismatch', 'Bloom Syndrome', 'Colorectal Neoplasms', 'DNA Repair', 'Disease Models, Animal', 'Fanconi Anemia', 'Humans', 'Mice', 'Mice, Knockout', 'Mutation', 'Phenotype', 'Skin Neoplasms', 'Xeroderma Pigmentosum'] | 12,013,614 | [['B01.050'], ['C10.228.140.252.190.530.060', 'C10.562.100', 'C10.597.350.090.500.530.060', 'C14.907.823.213', 'C16.320.080', 'C16.320.798.250', 'C18.452.284.060', 'C20.673.795.250'], ['G05.365.590.060'], ['C16.131.077.137', 'C16.320.798.313', 'C18.452.284.100', 'C20.673.795.313'], ['C04.588.274.476.411.307', 'C06.301.... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The 3'-untranslated sequence of human skeletal muscle alpha-actin mRNA. | A human actin cDNA clone pGF3 isolated from a fetal skeletal muscle cDNA library is described. The insert cDNA is homologous to skeletal muscle alpha-actin as judged by restriction mapping and nucleotide sequencing. The recombinant contains a substantial portion of the coding and the complete 3'-untranslated region. Co... | ['Actins', 'Base Sequence', 'Cloning, Molecular', 'DNA', 'DNA Restriction Enzymes', 'Female', 'Fetus', 'Humans', 'Muscles', 'Nucleic Acid Hybridization', 'Plasmids', 'Poly A', 'Pregnancy', 'Protein Biosynthesis', 'RNA', 'RNA, Messenger'] | 6,207,203 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['A16.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Spirituality and psychosocial factors in persons living with HIV. | AIM OF THE STUDY: This pilot study was designed to examine the relationships among spirituality and psychosocial factors in a sample of 52 adult males living with human immunodeficiency virus (HIV) disease and to determine the most reliable spirituality measure for a proposed longitudinal study.BACKGROUND: HIV disease ... | ['Activities of Daily Living', 'Adaptation, Psychological', 'Adult', 'Attitude to Health', 'Cost of Illness', 'Existentialism', 'Follow-Up Studies', 'HIV Infections', 'Health Status', 'Humans', 'Male', 'Models, Psychological', 'Nursing Methodology Research', 'Pilot Projects', 'Quality of Life', 'Religion and Psychology... | 11,298,215 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['F01.058'], ['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['F02.739.418', 'K01.752.304'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Humanities [K]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Anti-apoptotic effect of phloretin on cisplatin-induced apoptosis in HEI-OC1 auditory cells. | Cisplatin is a highly effective chemotherapeutic agent, but it has significant ototoxic side effects. Apoptosis is an important mechanism of cochlear hair cell loss following exposure to cisplatin. The present study examined the effects of phloretin, a natural polyphenolic compound found in apples and pears, on cisplat... | ['Animals', 'Antineoplastic Agents', 'Apoptosis', 'Cell Line', 'Cisplatin', 'Dose-Response Relationship, Drug', 'Gene Expression Regulation, Enzymologic', 'Heme Oxygenase-1', 'JNK Mitogen-Activated Protein Kinases', 'Mice', 'NF-E2-Related Factor 2', 'Organ of Corti', 'Phloretin', 'Time Factors'] | 21,857,081 | [['B01.050'], ['D27.505.954.248'], ['G04.146.954.035'], ['A11.251.210'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['G07.690.773.875', 'G07.690.936.500'], ['G05.308.320'], ['D08.811.682.690.708.410.500'], ['D08.811.913.696.620.682.700.567.374', 'D12.644.360.450.340', 'D12.776.476.450.340'], ['B01.050.150.900.649.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of step size on clinical and adaptive 2IFC procedures in quiet and in a noise background. | Audibility thresholds for a 1000-Hz sinusoid were measured with a standard clinical (CLIN) procedure and a two-interval, forced-choice (2IFC) adaptive procedure bracketing 79% correct. Both used 2- and 5-dB step sizes in quiet and in a continuous, broadband noise background. Clinical thresholds were from 2 to 4 dB high... | ['Adult', 'Audiometry, Pure-Tone', 'Auditory Perception', 'Auditory Threshold', 'Computer Simulation', 'Humans', 'Middle Aged', 'Noise', 'Reproducibility of Results'] | 8,844,550 | [['M01.060.116'], ['E01.370.382.375.060.055'], ['F02.463.593.071', 'G07.888.125'], ['F02.463.593.071.173', 'F02.463.593.710.190', 'G07.888.125.173'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G01.750.770.776.567', 'G16.500.275.600', 'N06.230.400', 'N06.850.460.610'], ['E05... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Splenic metastases in gynaecologic cancer: clinical considerations, US, and CT diagnostic results. | PURPOSE: Splenic metastases from lesions in the genital system are an uncommon finding, both at staging and at follow-up. Most metastases are not an isolated finding but are quite frequently associated with metastases to lymph node or parenchymal sites. The aim of this paper is to describe the patterns of splenic metas... | ['Aged', 'Contrast Media', 'Diagnosis, Differential', 'Female', 'Genital Neoplasms, Female', 'Humans', 'Middle Aged', 'Neoplasm Staging', 'Predictive Value of Tests', 'Retrospective Studies', 'Sensitivity and Specificity', 'Splenic Neoplasms', 'Tomography, X-Ray Computed', 'Ultrasonography, Doppler'] | 12,951,549 | [['M01.060.116.100'], ['D27.505.259.500', 'D27.720.259'], ['E01.171'], ['C04.588.945.418', 'C13.351.937.418'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.625'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E05.318.372.500.500.500', 'E05.318.372.50... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[The combined application of visual evoked potentials and the quantified electroencephalogram improve discrimination of cerebral maturity]. | INTRODUCTION AND OBJECTIVE: The aim of this job is to evaluate brain maturation by means of Electroencephalogram (EEG) and Visual Evoked Potentials stimulated with flash (VEP-flash) quantitative analysis techniques.MATERIAL AND METHODS: The transversal study is made on a sample of 96 subjects in which EEG and VEP-flash... | ['Adolescent', 'Adult', 'Brain', 'Child', 'Child, Preschool', 'Electroencephalography', 'Evoked Potentials, Visual', 'Female', 'Humans', 'Male'] | 9,340,142 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500.425', 'G11.561.200.500.425', 'G14.330'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Minor envelope proteins of duck hepatitis B virus are initiated at internal pre-S AUG codons but are not essential for infectivity. | In infected liver tissue three major and several minor duck hepatitis B virus (DHBV) envelope proteins are detectable by immunoblotting. Translation initiation at the second and the most distal internal ATG codon of the Pre-S/S gene is known to lead to synthesis of two major envelope proteins (P36 and P17) whereas the ... | ['Animals', 'Base Sequence', 'Carcinoma, Hepatocellular', 'Codon', 'DNA Primers', 'Ducks', 'Hepatitis Virus, Duck', 'Hepatoblastoma', 'Humans', 'Liver Neoplasms', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Oligodeoxyribonucleotides', 'Polymerase Chain Reaction', 'Transfection', 'Tumor Cells, Cultured', '... | 8,212,596 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['B01.050.150.900.248.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Chlamydia pneumoniae--induced macrophage foam cell formation is mediated by Toll-like receptor 2. | Chlamydia pneumoniae induces macrophage foam cell formation, a hallmark of early atherosclerosis, in the presence of low-density lipoprotein (LDL). This study examined the role that Toll-like receptor 2 (TLR2) and TLR4 may play in pathogen-induced foam cell formation. Murine macrophage RAW 264.7 cells either infected w... | ['Animals', 'Benzoates', 'Benzylamines', 'Cell Line', 'Cells, Cultured', 'Chlamydophila Infections', 'Chlamydophila pneumoniae', 'Cholesterol Esters', 'DNA-Binding Proteins', 'Foam Cells', 'Lipopolysaccharides', 'Lipoproteins', 'Liver X Receptors', 'Macrophages', 'Macrophages, Peritoneal', 'Male', 'Mice', 'Mice, Inbred... | 17,145,941 | [['B01.050'], ['D02.241.223.100', 'D02.455.426.559.389.127'], ['D02.092.200', 'D02.455.426.559.389.140.210'], ['A11.251.210'], ['A11.251'], ['C01.150.252.400.210.250'], ['B03.440.190.190.230.249'], ['D04.210.500.247.222.284.200', 'D04.210.500.247.808.197.200', 'D10.570.938.208.250'], ['D12.776.260'], ['A11.329.372.368'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The AB-variant of metachromatic leukodystrophy (postulated activator protein deficiency). Light and electron microscopic findings in a sural nerve biopsy. | THe histopathological findings in a sural nerve biopsy of a new distinct variant of metachromatic leukodystrophy (MLD) are compared to those of classical MLD. The clinical and histological features are typical of a sulfatide lipidosis, yet in vitro activities of arylsulfatases A and B and cerebroside sulfatase are norm... | ['Adult', 'Arylsulfatases', 'Biopsy', 'Cerebroside-Sulfatase', 'Consanguinity', 'Female', 'Humans', 'Leukodystrophy, Metachromatic', 'Sural Nerve'] | 6,120,612 | [['M01.060.116'], ['D08.811.277.352.827.070'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['D08.811.277.352.827.070.250'], ['G05.090.403.180', 'G05.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.16... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Strongly increased exposure of meloxicam in CYP2C9*3/*3 individuals. | OBJECTIVE: The effects of CYP2C9*1/*3 and *3/*3 genotypes on the pharmacokinetics and pharmacodynamics of meloxicam were evaluated in healthy Korean subjects.METHODS: After oral administration of 15 mg meloxicam, the plasma concentrations of meloxicam were assessed in 11 CYP2C9*1/*1 individuals, eight CYP2C9*1/*3 indiv... | ['Anti-Inflammatory Agents, Non-Steroidal', 'Aryl Hydrocarbon Hydroxylases', 'Asian Continental Ancestry Group', 'Cytochrome P-450 CYP2C9', 'Genetic Variation', 'Genotype', 'Humans', 'Male', 'Meloxicam', 'Metabolic Clearance Rate', 'Polymorphism, Genetic', 'Thiazines', 'Thiazoles', 'Thromboxane B2'] | 24,322,170 | [['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D08.244.453.005', 'D08.811.682.690.708.170.010', 'D12.776.422.220.453.010'], ['M01.686.508.200'], ['D08.244.453.491.500.500', 'D08.811.682.690.708.170.450.500.500', 'D12.776.422.220.453.491.500.500'], ['G05.365'], ['G05.380'], ['B01.0... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
GABAergic inhibition of neuronal activity in the primate motor and premotor cortex during voluntary movement. | 1. The functional role of GABAergic inhibition in neuronal activity in the forearm-hand area of the motor cortex and the postarcuate premotor cortex was studied while monkeys pressed and released a lever in response to a visual cue. gamma-Aminobutyric acid (GABA), its agonist muscimol (MUS), and its antagonist bicucull... | ['Animals', 'Bicuculline', 'Iontophoresis', 'Macaca', 'Macaca mulatta', 'Motor Cortex', 'Movement', 'Muscimol', 'Neural Inhibition', 'Neurons', 'Volition', 'gamma-Aminobutyric Acid'] | 1,432,042 | [['B01.050'], ['D03.132.098.077', 'D03.633.100.531.085.077'], ['E02.319.267.650', 'E05.301.300.575'], ['B01.050.150.900.649.313.988.400.112.199.120.510'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['G07.568', 'G11.427.410'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A suggested mode of inheritance for wool shedding in sheep. | The ability of a sheep to shed its own wool has an attraction in scenarios where the costs of harvesting wool outweigh its value. Certain breeds and composites have the ability to shed their wool in the spring, and these are investigated in this work in an attempt to outline the genetics of wool shedding. One flock fro... | ['Animals', 'Breeding', 'Female', 'Genes, Dominant', 'Genotype', 'Male', 'Phenotype', 'Selection, Genetic', 'Sheep', 'Wool'] | 21,357,446 | [['B01.050'], ['E05.820.150', 'G05.090'], ['G05.360.340.024.340.240', 'G05.420.320'], ['G05.380'], ['G05.695'], ['G05.783'], ['B01.050.150.900.649.313.500.380.791'], ['A13.970', 'A17.360.855']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The measurement of health related quality of life]. | The measurement of health-related quality of life (HRQOL) plays a very important role in the study of health outcomes, particularly in effectiveness studies. Nevertheless, the nature of these studies implies a series of challenges in the use of HRQOL instruments, due to the type of comparisons made, the heterogeneity o... | ['Cost of Illness', 'Humans', 'Outcome Assessment, Health Care', 'Quality of Life', 'Sickness Impact Profile'] | 10,994,560 | [['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E05.318.308.980.438.475.730', 'N05.715.360.300.800.... | ['Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Unexpected complication: renal parenchymal perforation with double-J ureteral stent. | Double-J ureteral stent is commonly used in various endourological procedures. This procedure may cause some complication. We present a case of renal parenchymal perforation due to double-J stent insertion. | ['Hematoma', 'Humans', 'Kidney Diseases', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prosthesis Implantation', 'Stents', 'Ureter'] | 18,769,908 | [['C23.550.414.838'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419', 'C13.351.968.419'], ['M01.060.116.630'], ['C23.550.767'], ['E04.650'], ['E07.695.750'], ['A05.810.776']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The precautionary principle is incoherent. | This article argues that no version of the precautionary principle can be reasonably applied to decisions that may lead to fatal outcomes. In support of this strong claim, a number of desiderata are proposed, which reasonable rules for rational decision making ought to satisfy. Thereafter, two impossibility theorems ar... | ['Death', 'Decision Making', 'Decision Theory', 'Environmental Health', 'Environmental Pollution', 'Humans', 'Policy Making', 'Public Health', 'Risk', 'Risk Assessment', 'Risk Management'] | 16,834,620 | [['C23.550.260'], ['F02.463.785.373'], ['G17.162'], ['H02.229'], ['N06.850.460'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.706.742'], ['H02.403.720', 'N01.400.550', 'N06.850'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600.800'], ['E05.318.740.600.800.715', 'N04.45... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
[Time-series analysis applied to nosocomial infection]. | BACKGROUND: In this study we introduce a new view of hospital infection, to apply time series techniques to it. Our objective is to complement hospital infection's epidemiological surveillance by means of obtaining alert and alarm thresholds that make easy to the epidemiologist the decision of intervention, in case the... | ['Analysis of Variance', 'Cross Infection', 'Humans', 'Incidence', 'Models, Statistical', 'Prognosis', 'Seasons', 'Spain'] | 1,630,180 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C01.248', 'C23.550.291.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Innate Immune B Cell Activation by Leishmania donovani Exacerbates Disease and Mediates Hypergammaglobulinemia. | Participation of B cells in the immune response by various antibody-independent mechanisms has recently been uncovered. B cells producing cytokines have been described for several infections and appear to regulate the adaptive immune response. B cell activation by Leishmania donovani results in disease exacerbation. Ho... | ['Animals', 'B-Lymphocytes', 'Disease Progression', 'Endosomes', 'Hypergammaglobulinemia', 'Immunity, Innate', 'Interferon Type I', 'Interleukin-10', 'Leishmania donovani', 'Leishmaniasis', 'Lymphocyte Activation', 'Membrane Transport Proteins', 'Mice, Inbred C57BL', 'RNA, Messenger', 'Receptor, Interferon alpha-beta',... | 27,264,176 | [['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['C23.550.291.656'], ['A11.284.430.214.190.875.190.880.337'], ['C15.378.147.542', 'C20.683.460', 'C23.888.512'], ['G12.450.564'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', ... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Endocrine complications of modern cancer therapy]. | Treatment with tyrosine kinase inhibitors leads to thyroid dysfunction in up to one half of treated patients, hypothyroidism being the most common. It is caused by destructive thyroiditis, impaired transport of T4 into the cell and deiodinase induction. Bexarotene is a nuclear retinoid X receptor agonist. Its applicati... | ['Antibodies, Monoclonal', 'Anticarcinogenic Agents', 'Antineoplastic Agents', 'Bexarotene', 'CTLA-4 Antigen', 'Humans', 'Hypophysitis', 'Hypothyroidism', 'Immunotherapy', 'Ipilimumab', 'Neoplasms', 'Protein Kinase Inhibitors', 'Tetrahydronaphthalenes', 'Thyroid Diseases', 'Thyroiditis, Autoimmune', 'Thyroxine'] | 27,734,691 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D27.505.696.706.018', 'D27.505.954.248.125', 'D27.720.799.018'], ['D27.505.954.248'], ['D02.455.426.559.847.638.960.423', 'D04.615.638.960.423'], ['D12.776.465.782', 'D12.776.543.750.705.222.750', 'D23.050.301.264.894.158'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Behavior of the primary care physicians in the treatment of community infections]. | This study aimed to evaluate the behavior of the physicians who attend to patients with community infections who are responsible for most of the antibiotic prescriptions made in the community setting. Furthermore, the evolution over the last 10 years in regards to the treatment habits of the most frequent infections in... | ['Adult', 'Aged', 'Anti-Infective Agents', 'Child', 'Community-Acquired Infections', 'Humans', "Practice Patterns, Physicians'", 'Primary Health Care', 'Surveys and Questionnaires'] | 18,443,927 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.122'], ['M01.060.406'], ['C01.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.374.577', 'N05.300.625'], ['N04.590.233.727'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Incidental 18F-FDG PET/CT bilateral breast uptake due to carcinoma. | We report a case of 71-year-old female patient, previously treated with chemotherapy and surgical resection of sigmoid tract of the large bowel for adenocarcinoma (pT3N1M0), who underwent a 18F-FDG PET/CT for a suspicious hepatic lesion detected at CT scan during follow-up. 18F-FDG PET/CT showed no abnormal uptake in t... | ['Adenocarcinoma', 'Aged', 'Breast Neoplasms', 'Carcinoma, Papillary', 'Colonic Neoplasms', 'Female', 'Fluorodeoxyglucose F18', 'Humans', 'Incidental Findings', 'Liver', 'Neoplasms, Multiple Primary', 'Positron Emission Tomography Computed Tomography', 'Radiopharmaceuticals'] | 27,900,755 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.360', 'C04.557.470.700.360'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['D09.254.229.500'], ['B01.050.150.900.649.313.9... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Blood pressure reduction during hemodialysis correlates to intradialytic changes in plasma volume. | Blood pressure alterations during hemodialysis were related to changes in body fluid in 14 patients with chronic renal failure. Changes in plasma volume (PV) and extracellular volume (ECV) were calculated from determinations of fluid volumes before and after hemodialysis, using 125I-albumin and 51Cr EDTA respectively. ... | ['Adult', 'Aged', 'Blood Pressure', 'Body Fluid Compartments', 'Female', 'Heart Rate', 'Humans', 'Male', 'Middle Aged', 'Osmolar Concentration', 'Plasma Volume', 'Renal Dialysis'] | 1,638,783 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.875.249', 'G09.330.380.076'], ['A10.082', 'A12.207.180'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G02.640'], ['G09.188.130.610', 'G09.330.380.092.610'], ['E02.870.300', 'E02.912.800']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
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