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[Villous adenoma of Vater's papilla; a therapeutic dilemma]. | After a cholecystectomy in 1980, local excision of a villous adenoma of the ampulla of Vater was performed in 1983 in a 69-year-old female; this had to be repeated in 1990 because of recurrence. In case of a tumour of this kind, pancreaticoduodenectomy should be considered because of the relatively high risk of recurre... | ['Adenocarcinoma', 'Adenoma', 'Aged', 'Ampulla of Vater', 'Cell Transformation, Neoplastic', 'Common Bile Duct Neoplasms', 'Female', 'Humans', 'Neoplasm Recurrence, Local'] | 1,620,256 | [['C04.557.470.200.025'], ['C04.557.470.035'], ['M01.060.116.100'], ['A03.159.183.079.300.950', 'A03.556.124.684.124.236', 'A03.556.875.249.160', 'A03.734.667.500'], ['C04.697.098.500', 'C23.550.727.098.500'], ['C04.588.274.120.250.250', 'C06.130.120.120.280', 'C06.130.120.250.280', 'C06.130.320.120.280', 'C06.301.120.... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Syndrome of microcephaly, mental retardation, and tracheoesophageal fistula associated with features of Rett syndrome. | We report a 12-year-old girl with features of the syndrome of microcephaly, mesobrachydactyly, and tracheoesophageal fistula, who also developed distinctive features of Rett syndrome including regression of milestones with repetitive actions, autistic-like behavior, stereotypic hand movements, and seizures. This unique... | ['Adolescent', 'Female', 'Humans', 'Intellectual Disability', 'Microcephaly', 'Phenotype', 'Rett Syndrome', 'Sex Chromosome Aberrations', 'Tracheoesophageal Fistula', 'X Chromosome'] | 10,641,614 | [['M01.060.057'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.360', 'C23.888.592.604.646', 'F01.700.687', 'F03.625.539'], ['C05.660.207.620', 'C10.500.507.400.500', 'C16.131.621.207.620', 'C16.131.666.507.400.500'], ['G05.695'], ['C10.597.606.360.455.937', 'C16.320.322.500.937', 'C16.320.400.525.937'... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Frequency of urinary incontinence in people with chronic heart failure. | OBJECTIVES: The purpose of the study was to examine the frequency and severity of urinary incontinence in people with heart failure (HF). Secondary aims were to determine the differences in known risk factors for those who were continent and incontinent, to investigate the correlates of urinary incontinence in people w... | ['Activities of Daily Living', 'Adult', 'Aged', 'Aged, 80 and over', 'Cross-Sectional Studies', 'Female', 'Heart Failure', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Prospective Studies', 'Quality of Life', 'Queensland', 'Risk Factors', 'Surveys and Questionnaires', 'Urinary Incontinence', 'Young Adult'] | 23,122,947 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Antimicrobial resistance in septic-purulent infections. | UNLABELLED: Evaluating the spread of antibiotic-resistant microorganisms from a multi-profile hospital.MATERIALS AND METHODS: There were analyzed 3940 strains of antibiotic-resistant microorganisms from patients with septic-purulent infections.RESULTS: From the total, 51.44% samples of isolated strains showed resistanc... | ['Anti-Bacterial Agents', 'Bacteremia', 'Bacterial Infections', 'Cephalosporins', 'Drug Resistance, Multiple, Bacterial', 'Gram-Negative Bacterial Infections', 'Gram-Positive Bacterial Infections', 'Humans', 'Klebsiella Infections', 'Klebsiella pneumoniae', 'Microbial Sensitivity Tests', 'Penicillins', 'Suppuration'] | 24,340,531 | [['D27.505.954.122.085'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['C01.150.252'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.300.249'], ['G06.099.225.812', 'G06.225.347.812', 'G07.690.773.984.269.347.812', 'G07.690.773.984.300.500'], ['C01.150.252.400'], ['C01.150.252.410'], ['B01.0... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gene expression patterns in visual cortex during the critical period: synaptic stabilization and reversal by visual deprivation. | The mapping of eye-specific, geniculocortical inputs to primary visual cortex (V1) is highly sensitive to the balance of correlated activity between the two eyes during a restricted postnatal critical period for ocular dominance plasticity. This critical period is likely to have amplified expression of genes and protei... | ['Animals', 'Critical Period, Psychological', 'Dominance, Ocular', 'Down-Regulation', 'Gene Expression Profiling', 'Gene Expression Regulation, Developmental', 'Inhibitory Postsynaptic Potentials', 'Mice', 'Myelin Sheath', 'Neurons', 'Reproducibility of Results', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sens... | 18,606,990 | [['B01.050'], ['F02.463.425.209'], ['G11.561.225.425.500', 'G14.264'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['E05.393.332'], ['G05.308.310'], ['G04.580.887.374', 'G07.265.675.887.374', 'G07.265.755.500', 'G07.265.880.750.400', 'G11.561.570.918.374', 'G11.561.616.500', 'G11.561.830.750.400'], ['B01.050.150... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Evolution of follistatin in teleosts revealed through phylogenetic, genomic and expression analyses. | Follistatin (Fst) inhibits transforming growth factor-beta (TGF-B) proteins and is a known regulator of amniote myogenesis. Here, we used phylogenetic, genomic and experimental approaches to study its evolution in teleosts. Phylogenetic analyses suggested that one fst gene (fst1) is common to euteleosts, but a second g... | ['Animals', 'Base Sequence', 'Cluster Analysis', 'Computational Biology', 'DNA Primers', 'Evolution, Molecular', 'Fishes', 'Follistatin', 'Gene Expression', 'Genes, Duplicate', 'Genomics', 'In Situ Hybridization', 'Molecular Sequence Data', 'Phylogeny', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sequence Analy... | 18,074,148 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['H01.158.273.180', 'L01.313.124'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['G05.045.250', 'G16.075.250'], ['B01.050.150.900.493'], ['D12.776.157.247'], ['G05.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Cost of hypertension control at the workplace. | A cost analysis of hypertension treatment at the workplace indicates that average patient cost in 1978 was $194.77. The distribution of cost is: clinical personnel, 26.7%; administrative personnel, 26.7%; drugs, 23.9%; laboratory, 3.4%; clinical supplies, 1.1%; general supplies and other operating expenses, 8.7%; equip... | ['Costs and Cost Analysis', 'Humans', 'Hypertension', 'Occupational Health Services'] | 7,218,056 | [['N03.219.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['N02.421.143.740']] | ['Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Chronic phosphocreatine depletion by the creatine analogue beta-guanidinopropionate is associated with increased mortality and loss of ATP in rats after myocardial infarction. | BACKGROUND: The failing myocardium is characterized by reductions of phosphocreatine (PCr) and free creatine content and by decreases of energy reserve via creatine kinase (CK), ie, CK reaction velocity (Flux(CK)). It has remained unclear whether these changes contribute directly to contractile dysfunction. In the pres... | ['Adenosine Triphosphate', 'Animals', 'Blood Flow Velocity', 'Body Weight', 'Chronic Disease', 'Coronary Circulation', 'Coronary Vessels', 'Disease Models, Animal', 'Guanidines', 'Heart', 'Heart Rate', 'Homeostasis', 'In Vitro Techniques', 'Ligation', 'Magnetic Resonance Spectroscopy', 'Myocardial Infarction', 'Organ S... | 11,591,624 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['E01.370.370.130', 'G09.330.380.630.080'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C23.550.291.500'], ['G09.330.100.324'], ['A07.015.114.269', 'A07... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A randomized double-blind controlled trial comparing three sedation regimens during flexible bronchoscopy: Dexmedetomidine, alfentanil and lidocaine. | INTRODUCTION: No standardized sedation protocol is available for flexible bronchoscopy (FB).OBJECTIVES: The aim of this study was to evaluate the efficacy and safety of three regimens used for sedation during FB.METHODS: This randomized double-blind controlled trial assessed patients undergoing bronchoscopy and receivi... | ['Adolescent', 'Adult', 'Aged', 'Alfentanil', 'Analgesics, Non-Narcotic', 'Analgesics, Opioid', 'Anesthetics, Local', 'Bronchoscopy', 'Conscious Sedation', 'Dexmedetomidine', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Female', 'Follow-Up Studies', 'Humans', 'Lidocaine', 'Male', 'Middle Aged', 'Pain', '... | 28,779,544 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D03.383.621.265.100'], ['D27.505.696.663.850.014.040', 'D27.505.954.427.040.100'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Expression of ecdysteroid-regulated genes is reduced specifically in the wing discs of the wing-deficient mutant (fl) of Bombyx mori. | The wing-deficient mutant, fl?gellos (fl), of the silkworm, lacks four wings in the pupa and the adult. Previous studies have suggested that the fl wing discs lose responsiveness to ecdysteroid during metamorphosis. To test this hypothesis at the molecular level we compared the expression of 12 genes when the wing disc... | ['Animals', 'Base Sequence', 'Bombyx', 'DNA Primers', 'Ecdysterone', 'Gene Expression Regulation', 'Metamorphosis, Biological', 'Mutation', 'Wings, Animal'] | 11,180,812 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.050.500.131.617.720.500.500.937.650.100'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D04.210.500.247.222.265.165.750', 'D06.472.445.573.271.750'], ['G05.308'], ['G07.345.500.550'], ['G05.365.590'], ['A13.395.823']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Perceived discrimination and mental health symptoms among Black men with HIV. | People living with HIV (PLWH) exhibit more severe mental health symptoms, including depression and posttraumatic stress disorder (PTSD) symptoms, than do members of the general public. We examined whether perceived discrimination, which has been associated with poor mental health in prior research, contributes to great... | ['Adult', 'African Americans', 'Cross-Sectional Studies', 'Depression', 'Discrimination, Psychological', 'HIV Infections', 'Homosexuality, Male', 'Humans', 'Los Angeles', 'Male', 'Mental Health', 'Middle Aged', 'Perception', 'Psychiatric Status Rating Scales', 'Socioeconomic Factors', 'Stress Disorders, Post-Traumatic'... | 21,787,061 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.126.350'], ['F02.463.593.257'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['F01.145.802... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
The cellular mechanism by which the human endogenous retrovirus ERV-3 env gene affects proliferation and differentiation in a human placental trophoblast model, BeWo. | The env region of the human endogenous retrovirus ERV-3 is expressed during differentiation of trophoblast and the choriocarcinoma BeWo. Stable transfectants with ERV-3 env exhibit most aspects of trophoblast differentiation, including inhibition of cell proliferation, changes in cell morphology, and increased producti... | ['Cell Differentiation', 'Cell Division', 'Choriocarcinoma', 'Chorionic Gonadotropin', 'Cyclic AMP-Dependent Protein Kinases', 'Cyclin B', 'Endogenous Retroviruses', 'Enzyme Inhibitors', 'Female', 'Gene Expression', 'Genes, env', 'Humans', 'Isoquinolines', 'Pregnancy', 'Sulfonamides', 'Transfection', 'Trophoblasts', 'T... | 10,692,254 | [['G04.152'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['C04.557.465.955.207', 'C04.557.470.200.025.455', 'C04.850.908.208', 'C13.703.720.949.208'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['D08.811.913.696.620.682.700.150.125', 'D12.644... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Alteration in sperm characteristics, endocrine balance and redox status in rats rendered diabetic by streptozotocin treatment: attenuating role of Loranthus micranthus. | OBJECTIVES: Loranthus micranthus is widely used in Nigerian folklore treatment of male infertility and diabetes complications. We investigated this claim in rats rendered diabetic by streptozotocin (STZ).METHODS: Induction of diabetes mellitus in adult male Wistar rats was by intraperitoneal injection of STZ (60 mg/kg... | ['Animals', 'Antioxidants', 'Diabetes Mellitus, Experimental', 'Lipid Peroxidation', 'Loranthaceae', 'Male', 'Oxidative Stress', 'Plant Extracts', 'Rats', 'Rats, Wistar', 'Spermatozoa', 'Testis'] | 30,376,784 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['G02.111.515', 'G03.295.531.587'], ['B01.650.940.800.575.912.250.735.249'], ['G03.673', 'G07.775.750'], ['D20.215.784.500', 'D26.667'], ['B01.050.150.900.649.313.992.635.505.700'], ['... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Body position and breathing abnormalities during sleep: a systematic study. | BACKGROUND: Until now, studies about body position and nocturnal breathing abnormalities have been restricted to comparing supine versus lateral positions.OBJECTIVES: In this retrospective study, we systematically evaluated the effect of body position on nocturnal breathing in 105 patients with a sleep apnea hypopnea s... | ['Algorithms', 'Female', 'Humans', 'Male', 'Middle Aged', 'Polysomnography', 'Posture', 'Prone Position', 'Retrospective Studies', 'Sleep Apnea, Obstructive', 'Statistics, Nonparametric', 'Supine Position'] | 22,420,172 | [['G17.035', 'L01.224.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.520.625'], ['G11.427.695'], ['G11.427.695.525'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.4... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Activation of Ha-ras p21 by substitution, deletion, and insertion mutations. | The transforming activity of naturally arising ras oncogenes results from point mutations that affect residue 12 or 61 of the encoded 21-kilodalton protein (p21). By use of site-directed mutagenesis, we showed that deletions and insertions of amino acid residues in the region of residue 12 are also effective in conferr... | ['Base Sequence', 'Cell Transformation, Neoplastic', 'Chromosome Deletion', 'DNA Transposable Elements', 'Humans', 'Mutation', 'Neoplasm Proteins', 'Nucleic Acid Hybridization', 'Oncogenes', 'Plasmids', 'Protein Conformation'] | 3,018,526 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['C04.697.098.500', 'C23.550.727.098.500'], ['C23.550.210.050.500.500', 'G05.365.590.029.530.175', 'G05.365.590.175.050.500.500', 'G05.365.590.762.180', 'G05.558.800.180', 'G05.700.131.500.500'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Sequential docetaxel as adjuvant chemotherapy for node-positive or/and T3 or T4 breast cancer: clinical outcome (Mansoura University). | This trial compared 6 cycles of fluorouracil, epirubicin, and cyclophosphamide (FEC) with a sequential regimen of 3 cycles of FEC followed by 3 cycles of docetaxel (FEC-D) as adjuvant treatment for women with node-positive or/and T3 or T4 breast cancer. Between January 2006 and January 2010, 657 patients with operable ... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Breast Neoplasms', 'Chemoradiotherapy', 'Chemotherapy, Adjuvant', 'Cyclophosphamide', 'Disease-Free Survival', 'Docetaxel', 'Epirubicin', 'Female', 'Fluorouracil', 'Humans', 'Kaplan-Meier Estimate', 'Lymphatic Metastasis', 'Mastectomy, Segmental', 'Mi... | 23,322,524 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.588.180', 'C17.800.090.500'], ['E02.186.079', 'E02.319.164', 'E02.815.160'], ['E02.186.170', 'E02.319.170'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Neuroprotection mediated through estrogen receptor-alpha in astrocytes. | Estrogen has well-documented neuroprotective effects in a variety of clinical and experimental disorders of the CNS, including autoimmune inflammation, traumatic injury, stroke, and neurodegenerative diseases. The beneficial effects of estrogens in CNS disorders include mitigation of clinical symptoms, as well as atten... | ['Animals', 'Astrocytes', 'Cells, Cultured', 'Encephalomyelitis, Autoimmune, Experimental', 'Estrogen Receptor alpha', 'Inflammation', 'Ligands', 'Mice', 'Mice, Knockout', 'Neurodegenerative Diseases', 'Neurons', 'Neuroprotective Agents'] | 21,555,578 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['A11.251'], ['C10.114.703.300', 'C10.228.140.695.562.250', 'C10.314.350.250', 'C20.111.258.625.300', 'E05.598.500.500.500'], ['D12.776.826.750.350.174'], ['C23.550.470'], ['D27.720.470.480'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Surgical management of anterior cavas foot in Charcot-Marie-Tooth patients. Five-year follow-up]. | UNLABELLED: Hereditary sensorimotor neuropathy involves foot deformities such as varus and cavus foot and claw toes. Several surgical techniques have been described to treat Charcot-Marie-Tooth disease.OBJECTIVE: To assess the clinical and functional result of "V" basal osteotomy of the central metatarsals with elevati... | ['Adolescent', 'Adult', 'Aged', 'Charcot-Marie-Tooth Disease', 'Female', 'Follow-Up Studies', 'Foot Deformities, Acquired', 'Humans', 'Longitudinal Studies', 'Male', 'Metatarsal Bones', 'Middle Aged', 'Osteotomy', 'Prospective Studies', 'Treatment Outcome', 'Young Adult'] | 27,012,083 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C10.500.300.200', 'C10.574.500.495.200', 'C10.668.829.800.300.200', 'C16.131.666.300.200', 'C16.320.400.375.200'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C05.330.488'], ['B01.050.150.900.649.313.988.400.112.4... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Occurrence of shigellosis in the young and elderly in rural China: results of a 12-month population-based surveillance study. | In 2002, population- and treatment center-based surveillance was used to study the disease burden of shigellosis in rural Hebei Province in the People's Republic of China. A total of 10,105 children with diarrhea or dysentery were enrolled. Infants were treated most frequently for diarrhea (1,388/1,000/year) followed b... | ['Adolescent', 'Age Distribution', 'Aged', 'Anti-Bacterial Agents', 'Child', 'Child, Preschool', 'China', 'Diarrhea', 'Dysentery, Bacillary', 'Humans', 'Infant', 'Microbial Sensitivity Tests', 'Middle Aged', 'Population Surveillance', 'Rural Population', 'Seasons', 'Shigella', 'Shigella flexneri'] | 16,103,614 | [['M01.060.057'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['D27.505.954.122.085'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.252.474.164'], ['C23.888.821.214'], ['C01.150.252.400.310.229', 'C06.405.205.331.479', 'C06.405.469.300.479'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Effect of the reducing-terminal substituents on the high energy collision-induced dissociation matrix-assisted laser desorption/ionization mass spectra of oligosaccharides. | High-energy collision-induced dissociation (CID) matrix-assisted laser desorption/ionization mass spectra of N-linked oligosaccharides bearing different, commonly encountered, reducing terminal modifications (hydroxyl, 2-aminobenzamide, asparagine and a tetrapeptide) were recorded on a magnetic sector instrument equipp... | ['Carbohydrate Sequence', 'Chromatography, High Pressure Liquid', 'Glycopeptides', 'Molecular Sequence Data', 'Oligosaccharides', 'Ribonucleases', 'Spectrometry, Fluorescence', 'Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization'] | 8,914,337 | [['G02.111.570.160', 'L01.453.245.667.160'], ['E05.196.181.400.300'], ['D09.400.420', 'D12.644.233'], ['L01.453.245.667'], ['D09.698.629'], ['D08.811.277.352.700'], ['E05.196.712.516.600.676', 'E05.196.867.726'], ['E05.196.566.755']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
An updated classification of retinal detachment with proliferative vitreoretinopathy. | The Retinal Society classification on proliferative vitreoretinopathy of 1983 has been updated to accommodate major progress in understanding of this disease. There are three grades describing increasing severity of the disease. Posterior and anterior location of the proliferations have been emphasized. A more detailed... | ['Eye Diseases', 'Humans', 'Retinal Detachment', 'Retinal Diseases', 'Vitreous Body'] | 1,867,299 | [['C11'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.768.648'], ['C11.768'], ['A09.371.714.500']] | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of four different beta-adrenoceptor blocking drugs on lymphocyte isoprenaline-stimulated cyclic AMP production. | 1 The influence of acebutolol, atenolol, pindolol and timolol on human lymphocyte cyclic AMP (cAMP) and its stimulation by isoprenaline in vitro has been studied. 2 Acebutolol and atenolol (10(-8)-10(-6)M) had no significant influence on lymphocyte cAMP levels or on isoprenaline-stimulated increase in cAMP. 3 Pindolol ... | ['Acebutolol', 'Adrenergic beta-Antagonists', 'Adult', 'Atenolol', 'Cyclic AMP', 'Drug Interactions', 'Female', 'Humans', 'Isoproterenol', 'Lymphocytes', 'Male', 'Middle Aged', 'Pindolol', 'Timolol'] | 6,115,666 | [['D02.033.100.624.698.025', 'D02.033.755.624.698.025', 'D02.092.063.624.698.025'], ['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116'], ['D02.033.100.624.698.070', 'D02.033.755.624.698.070', 'D02.092.063.624.698.070'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395'... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Management of cavernous malformations in the pediatric population. | The management of cavernous malformations (CMs) in a child is similar in many ways to that of CMs in an adult. There are specific general principles that need to be considered when approaching these lesions in children, however. The long life span anticipated in the pediatric patient may favor an aggressive surgical ap... | ['Adolescent', 'Central Nervous System Neoplasms', 'Child', 'Child, Preschool', 'Female', 'Hemangioma, Cavernous', 'Humans', 'Infant', 'Male', 'Patient Selection', 'Retrospective Studies', 'Treatment Outcome'] | 10,419,575 | [['M01.060.057'], ['C04.588.614.250', 'C10.551.240'], ['M01.060.406'], ['M01.060.406.448'], ['C04.557.645.375.385', 'C14.907.454.385', 'C15.378.463.515.385'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.581.500.653', 'N04.590.731'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
MicroRNA‑29a enhances cisplatin sensitivity in non‑small cell lung cancer through the regulation of REV3L. | Cisplatin‑based chemotherapy may greatly enhance patient prognosis; however, chemotherapy resistance remains an obstacle to curing patients with non‑small cell lung cancer (NSCLC). The aim of the present study was to explore the microRNAs (miRs) that could regulate cisplatin sensitivity and provide a potential treatmen... | ['A549 Cells', 'Apoptosis', 'Carcinoma, Non-Small-Cell Lung', 'Cell Line', 'Cell Line, Tumor', 'Cell Proliferation', 'Cisplatin', 'DNA-Binding Proteins', 'DNA-Directed DNA Polymerase', 'Drug Resistance, Neoplasm', 'HEK293 Cells', 'Humans', 'Lung Neoplasms', 'MicroRNAs', 'Prognosis', 'Up-Regulation'] | 30,535,450 | [['A11.251.210.190.080', 'A11.251.860.180.080', 'A11.436.054'], ['G04.146.954.035'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['A11.251.210'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D1... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Raman spectroscopic study on the iron oxide film prepared by iron oxidation method]. | Micro-Raman spectroscopy was used to investigate the chemical composition, microstructure and crystalline phase of an iron oxide sample with three-layer macro-structure prepared by iron oxidation. Two laser lines of 514 and 633 nm with a power of 0.5 mW on the sample were employed to excite the Raman spectra. Comparing... | ['Ferric Compounds', 'Iron', 'Lasers', 'Nanostructures', 'Nanotechnology', 'Oxidation-Reduction', 'Oxygen', 'Spectrum Analysis, Raman', 'X-Ray Diffraction'] | 15,762,525 | [['D01.490.100'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['E07.632.490', 'E07.710.520'], ['J01.637.512'], ['H01.603', 'J01.897.520.600'], ['G02.700', 'G03.295.531'], ['D01.268.185.550', 'D01.362.670'], ['E05.196.822.860', 'E05.196.867.890'], ['E05.196.309.742', 'E05.196.822.950', 'G01.867.950', 'G02... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Characterization of S628N: a novel KIT mutation found in a metastatic melanoma. | IMPORTANCE The KIT receptor is mutated in approximately 15%of acral, mucosal, and chronic, sun-damaged melanomas. The status of KIT mutations is of interest because they usually are mutually exclusive with N-RAS and B-RAF mutations and because of the availability of KIT kinase inhibitors in the clinic. Some recurrent K... | ['Aged, 80 and over', 'Animals', 'Benzamides', 'Cell Transformation, Neoplastic', 'Cells, Cultured', 'Colony-Forming Units Assay', 'Dasatinib', 'Fatal Outcome', 'Female', 'Fibroblasts', 'Humans', 'Imatinib Mesylate', 'Lung Neoplasms', 'Melanoma', 'Mutation, Missense', 'Phosphorylation', 'Piperazines', 'Point Mutation',... | 25,317,746 | [['M01.060.116.100.080'], ['B01.050'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['C04.697.098.500', 'C23.550.727.098.500'], ['A11.251'], ['E01.370.225.500.383', 'E05.200.500.383', 'E05.242.383'], ['D02.886.675.184', 'D03.383.129.708.198', 'D03.383.742.148'], ['E05.318.308.985.550.325', 'N0... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reversible lesions of the corpus callosum with initially restricted diffusion in a series of Caucasian children. | BACKGROUND: Reversible lesions of the corpus callosum with initial restricted diffusion on diffusion-weighted imaging (DWI) are rare and mainly described in the south Asiatic population.OBJECTIVE: The purpose of this study was to describe the clinical presentation, imaging findings, prognosis and etiology of transient ... | ['Adolescent', 'Brain Diseases', 'Charcot-Marie-Tooth Disease', 'Child', 'Corpus Callosum', 'Diffusion Magnetic Resonance Imaging', 'European Continental Ancestry Group', 'Female', 'Humans', 'Male', 'Prognosis', 'Retrospective Studies'] | 29,666,887 | [['M01.060.057'], ['C10.228.140'], ['C10.500.300.200', 'C10.574.500.495.200', 'C10.668.829.800.300.200', 'C16.131.666.300.200', 'C16.320.400.375.200'], ['M01.060.406'], ['A08.186.211.200.885.800.750'], ['E01.370.350.825.500.150'], ['M01.686.508.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789'], ['E05.... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Developing a U.K. protocol for collaborative care: a qualitative study. | OBJECTIVE: This study aimed to explore the views of stakeholders including patients, general practitioners (GPs) and mental health workers on the feasibility, acceptability and barriers to a collaborative care model for treatment of depression within the context of U.K. primary health care.METHOD: We used semistructure... | ['Attitude of Health Personnel', 'Cooperative Behavior', 'Decision Making', 'Depression', 'Feasibility Studies', 'Focus Groups', 'Humans', 'Interprofessional Relations', 'Interviews as Topic', 'Mental Health Services', 'Patient Acceptance of Health Care', 'Patient Care Team', 'Primary Health Care', 'Social Support', 'T... | 16,814,628 | [['F01.100.050', 'N05.300.100'], ['F01.145.813.115'], ['F02.463.785.373'], ['F01.145.126.350'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401.205'], ['E05... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 |
Amnionless-mediated glycosylation is crucial for cell surface targeting of cubilin in renal and intestinal cells. | Mutations in either cubilin (CUBN) or amnionless (AMN) genes cause Imerslund-Gr?sbeck syndrome (IGS), a hereditary disease characterised by anaemia attributed to selective intestinal malabsorption of cobalamin and low-molecular weight proteinuria. Although cubilin protein does not have a transmembrane segment, it funct... | ['Cell Membrane', 'Cells, Cultured', 'Endoplasmic Reticulum', 'Glycosylation', 'Humans', 'Intestinal Mucosa', 'Kidney', 'Membrane Proteins', 'Mutation, Missense', 'Protein Transport', 'Proteins', 'Receptors, Cell Surface'] | 29,402,915 | [['A11.284.149'], ['A11.251'], ['A11.284.430.214.190.875.248'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.369', 'A10.615.550.444'], ['A05.810.453'], ['D12.776.543'], ['G05.365.590.650'], ['G03.143.700'], ['D12.776'], ['D12.776.543.750']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Plantar loading forces while walking in a below-knee cast with an attached loadbearing frame. | BACKGROUND: We measured loading forces across different points of the plantar foot surface to examine how different types of casts affect load distribution through the foot and ankle. The patella tendon-bearing (PTB) or Sarmiento cast is the current "gold-standard" casting method for offloading force through the foot a... | ['Calcaneus', 'Casts, Surgical', 'Female', 'Foot Orthoses', 'Healthy Volunteers', 'Humans', 'Male', 'Metatarsal Bones', 'Walking', 'Weight-Bearing', 'Young Adult'] | 25,712,122 | [['A02.835.232.043.300.710.300'], ['E07.858.442.660.430.500', 'E07.858.690.725.430.500'], ['E07.858.442.743.659'], ['M01.774.500', 'M01.955.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.043.300.492'], ['G11.427.410.568.900', 'G11.427.410.698.277.937', 'I03.350.937', 'I03.450.642.845.940'], ['G01... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[Water quality comparison between Lake Taihu and contribute river during high water-level period]. | Thirty-two main rivers around Lake Taihu were sampled during high water period in 2008 to investigate river's vital impact on Lake water quality. Different forms of nitrogen and phosphorus were analyzed for the 32 river water samples according to nutrients function to algae. The aim of this study is to provide the basi... | ['China', 'Environmental Monitoring', 'Eutrophication', 'Lakes', 'Nitrogen', 'Organic Chemicals', 'Phosphorus', 'Rivers', 'Water Pollutants, Chemical'] | 22,279,890 | [['Z01.252.474.164'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G16.500.285'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['D01.268.604', 'D01.362.625'], ['D02'], ['D01.268.666'], ['G01.311.750', 'G16.500.275.280.650', 'N06.230.232.650'], ['D27.888.284.903.655']] | ['Geographicals [Z]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The intracisternal A particle derived solo LTR promoter of the rat oncomodulin gene is not present in the mouse gene. | The rat gene encoding oncomodulin, a small calcium-binding protein related to parvalbumin, is under the control of a solo long terminal repeat (LTR) derived from an endogenous intracisternal A-particle (IAP). This gene was the first example of a mammalian gene regulated in normal cells by a promoter of retroviral origi... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Calcium-Binding Proteins', 'Cell Line, Transformed', 'Genes', 'Genes, Intracisternal A-Particle', 'Humans', 'Mice', 'Molecular Sequence Data', 'Phylogeny', 'Promoter Regions, Genetic', 'Rats', 'Repetitive Sequences, Nucleic Acid', 'Sequence Alignment', 'Sequence Homo... | 1,468,649 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D12.776.157.125'], ['A11.251.210.172'], ['G05.360.340.024.340'], ['G02.111.570.080.708.330.800.200', 'G05.360.080.708.330.800.200', 'G05.360.340.024.340.364.875.360', 'G05.360.340.024.425.800.200', 'G0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Nitric oxide donors increase the pregnancy rate in patients with unexplained infertility undergoing clomiphene citrate stimulation and intrauterine insemination: a randomized controlled pilot study. | This study evaluated the effects of nitric oxide donor's treatment on the pregnancy rate and uterine blood flow in patients with unexplained infertility undergoing clomiphene citrate stimulation and intrauterine insemination. A total of 120 patients were randomly allocated to a control group who received 100 mg clomiph... | ['Administration, Intravaginal', 'Adult', 'Clomiphene', 'Egypt', 'Endometrium', 'Female', 'Fertility Agents, Female', 'Follicular Phase', 'Hospitals, University', 'Humans', 'Infertility, Female', 'Insemination, Artificial', 'Isosorbide Dinitrate', 'Nitric Oxide Donors', 'Ovulation Induction', 'Pilot Projects', 'Pregnan... | 27,809,622 | [['E02.319.267.120.500'], ['M01.060.116'], ['D02.455.426.559.389.150.700.125'], ['Z01.058.266.317'], ['A05.360.319.679.490'], ['D27.505.696.875.552.344', 'D27.505.954.705.552.344'], ['G08.686.605.310'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.70... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Cryotherapy is associated with improved clinical outcomes of Sorafenib therapy for advanced hepatocellular carcinoma. | We assessed the safety and efficacy of sorafenib with cryotherapy (cryoRx) in advanced hepatocellular carcinoma (HCC). One hundred four HCC patients were enrolled, who met the following criteria: (i) Barcelona Clinic Liver Cancer stage C; (ii) HCC without distant metastasis; (iii) the presence of portal vein thrombosis... | ['Antineoplastic Agents', 'Benzenesulfonates', 'Carcinoma, Hepatocellular', 'Combined Modality Therapy', 'Cryotherapy', 'Humans', 'Kaplan-Meier Estimate', 'Liver Neoplasms', 'Microvessels', 'Neoplasm Staging', 'Niacinamide', 'Phenylurea Compounds', 'Pyridines', 'Sorafenib', 'Treatment Outcome'] | 22,477,032 | [['D27.505.954.248'], ['D02.455.426.559.389.097', 'D02.886.645.600.080.050.100'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E02.186'], ['E02.258'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.6... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Second serogroup of Legionella quinlivanii isolated from two unrelated sources in the United Kingdom. | A series of strains, presumptively identified as legionellas on the basis of their nutritional requirements and biochemical reactivity, were isolated from two unrelated environmental sources in the UK. Representatives of each of these series had a restriction endonuclease digest pattern indistinguishable from that of t... | ['Air Conditioning', 'DNA, Bacterial', 'Fluorescent Antibody Technique', 'Immune Sera', 'Legionella', 'Polymorphism, Restriction Fragment Length', 'Sequence Homology, Nucleic Acid', 'Serotyping', 'United Kingdom', 'Water Microbiology'] | 1,684,788 | [['N06.230.150.050'], ['D13.444.308.212'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.114.573', 'D20.215.401'], ['B03.4... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Identification of dehydroxytrichostatin A as a novel up-regulator of the ATP-binding cassette transporter A1 (ABCA1). | The ATP-binding cassette transporter A1 (ABCA1) mediates the cellular efflux of excess cholesterol and phospholipids to lipid-poor apolipoprotein A-I (apoA-I). ABCA1 plays an important role in high-density lipoprotein (HDL) biogenesis and reverse cholesterol transport. By using a cell-based screening model for the ABCA... | ['ATP Binding Cassette Transporter 1', 'ATP-Binding Cassette Transporters', 'Animals', 'Cholesterol', 'Genes, Reporter', 'Hep G2 Cells', 'Histone Deacetylase Inhibitors', 'Humans', 'Hydroxamic Acids', 'Lipoproteins, HDL', 'Luciferases', 'Magnetic Resonance Spectroscopy', 'Mice', 'Molecular Structure', 'Promoter Regions... | 21,869,747 | [['D12.776.157.530.100.050.500', 'D12.776.395.550.020.381.500', 'D12.776.543.550.192.381.500', 'D12.776.543.585.100.190.500'], ['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['B01.050'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['G05.360.3... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An inhibitor of interferon action: II. Biological properties of the IFN-gamma-associated inhibitor of interferon action. | Previously an inhibitor of interferon action had been isolated from mitogen stimulated mouse spleen cells. This inhibitor was associated with the IFN-gamma molecule and might possibly represent an altered IFN-gamma molecule which can no longer induce an effective antiviral state. This report further investigates the bi... | ['Animals', 'Humans', 'Interferon-gamma', 'Kinetics', 'L Cells', 'Mengovirus', 'Mice', 'Vaccinia virus', 'Vesicular stomatitis Indiana virus', 'Viral Interference'] | 2,985,715 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.529.374.480.615.350'], ['G01.374.661', 'G02.111.490'], ['A11.251.210.505', 'A11.329.228.505'], ['B04.820.578.750... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exposure to polychlorinated compounds and cryptorchidism; A nested case-control study. | BACKGROUND: Maldescended testes or cryptorchidism is a genital birth defect that affects 2-9% of all male new-borns. Over the last 40 years there have been reports of increased prevalence in countries like the US, the UK and the Scandinavian countries. This possible increase has in some studies been linked to a foetal ... | ['Adult', 'Case-Control Studies', 'Cryptorchidism', 'Dichlorodiphenyl Dichloroethylene', 'Environmental Pollutants', 'Female', 'Gas Chromatography-Mass Spectrometry', 'Hexachlorobenzene', 'Humans', 'Hydrocarbons, Chlorinated', 'Infant, Newborn', 'Male', 'Maternal Exposure', 'Polychlorinated Biphenyls', 'Pregnancy', 'Pr... | 32,702,712 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C12.294.829.258', 'C12.706.258', 'C16.131.939.258', 'C19.391.829.258'], ['D02.455.526.439.292'], ['D27.888.284'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D02.455.426.559.389.261.400', 'D02.455.526.439.202.400'], ['B... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Challenges with Collecting Smoking Status in Electronic Health Records. | Smoking is the leading cause of preventable death in the United States. Obtaining patients' smoking status is the first step in delivering smoking cessation counseling. In this study, we assessed the quality of smoking status captured in an electronic health record from a large academic medical center. We analyzed data... | ['Academic Medical Centers', 'Data Accuracy', 'Documentation', 'Electronic Health Records', 'Humans', 'Medical Records Systems, Computerized', 'Retrospective Studies', 'Smoking', 'United States'] | 29,854,208 | [['N02.278.020'], ['E05.318.308.028', 'E05.318.370.725.250', 'L01.399.250.202', 'N05.715.360.300.202', 'N05.715.360.325.685.250'], ['L01.453.245'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.530.250', 'N06.850.520.308.940.968.625.250'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Innate immune responses of Drosophila melanogaster are altered by spaceflight. | Alterations and impairment of immune responses in humans present a health risk for space exploration missions. The molecular mechanisms underpinning innate immune defense can be confounded by the complexity of the acquired immune system of humans. Drosophila (fruit fly) innate immunity is simpler, and shares many simil... | ['Animals', 'Drosophila melanogaster', 'Escherichia coli', 'Escherichia coli Infections', 'Female', 'Gene Expression Profiling', 'Immunity, Innate', 'Male', 'Signal Transduction', 'Space Flight', 'Weightlessness'] | 21,264,297 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['E05.393.332'], ['G12.450.564'], ['G02.111.820', 'G04.835'], ['J01.937.285.850'], ['G01.060.350.369.400.900']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Protein Stains to Detect Antigen on Membranes. | Western blotting (protein blotting/electroblotting) is the gold standard in the analysis of complex protein mixtures. Electroblotting drives protein molecules from a polyacrylamide (or less commonly, of an agarose) gel to the surface of a binding membrane, thereby facilitating an increased availability of the sites wit... | ['Amido Black', 'Animals', 'Azo Compounds', 'Blotting, Western', 'Carbon', 'Coloring Agents', 'Gold Colloid', 'Humans', 'Membrane Proteins', 'Proteins', 'Rosaniline Dyes', 'Staining and Labeling'] | 26,139,252 | [['D02.172.029', 'D02.455.426.559.847.638.555.220', 'D02.886.645.600.080.050.650.025', 'D04.615.638.555.220'], ['B01.050'], ['D02.172'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D01.268.150'], ['D27.720.233'], ['D01.379.400'], ['B01.050.150.900.649.313.988.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Subjective and objective personal noise exposure and hypertension: an epidemiologic approach. | OBJECTIVES: Evidence for an association between chronic noise exposure and hypertension has been observed in several studies but suffers from limitations like crude exposure assessment. In this analysis, an association between noise exposure and hypertension was investigated using personal noise dosimeters.METHODS: Stu... | ['Adolescent', 'Adult', 'Aged', 'Blood Pressure Determination', 'Child', 'Environmental Exposure', 'Female', 'Germany', 'Humans', 'Hypertension', 'Loudness Perception', 'Male', 'Middle Aged', 'Noise', 'Risk Assessment', 'Young Adult'] | 21,761,214 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E01.370.370.140', 'E01.370.600.100'], ['M01.060.406'], ['N06.850.460.350'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['F02.463.593.071.576', 'G07.888.125.576'], ['M01.060.116.630'], ['G01.750.770.776.567', 'G16.500.275.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Blood cultures for women hospitalized with acute pelvic inflammatory disease. Are they necessary? | OBJECTIVE: To determine the incidence of positive blood cultures and if the results affect the clinical management or the duration of hospital stay in patients with acute pelvic inflammatory disease (PID).STUDY DESIGN: Retrospective study of all patients hospitalized with a diagnosis of acute PID from January 1, 1996, ... | ['Acute Disease', 'Adult', 'Bacteremia', 'Female', 'Hematologic Tests', 'Humans', 'Length of Stay', 'Needs Assessment', 'New Jersey', 'Pelvic Inflammatory Disease', 'Retrospective Studies', 'Unnecessary Procedures'] | 11,584,483 | [['C23.550.291.125'], ['M01.060.116'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['E01.370.225.625', 'E05.200.625'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['I02.594', 'N03.349.380.565', 'N05.300.537'], ['Z01.107.567.875.500.525'], ['C01.635.500... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Staging of Fatty Liver Diseases Based on Hierarchical Classification and Feature Fusion for Back-Scan-Converted Ultrasound Images. | Fatty liver disease is progressive and may not cause any symptoms at early stages. This disease is potentially fatal and can cause liver cancer in severe stages. Therefore, diagnosing and staging fatty liver disease in early stages is necessary. In this paper, a novel method is presented to classify normal and fatty li... | ['Algorithms', 'Fatty Liver', 'Humans', 'Image Enhancement', 'Image Interpretation, Computer-Assisted', 'Liver Cirrhosis', 'Sensitivity and Specificity', 'Ultrasonography', 'Wavelet Analysis'] | 27,694,278 | [['G17.035', 'L01.224.050'], ['C06.552.241'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['C06.552.630', 'C23.550.355.412'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
The chromatographic separation of factor VIII on aminohexyl sepharose. | A new method of factor VIII purification has been devised which involves chromatographic separation on aminohexyl-substituted agarose. Relatively large volumes of starting material can be processed compared to the volume of agarose employed and satisfactory yields are obtained. Factor-VIII-clotting activity is separate... | ['Animals', 'Antigens', 'Chromatography, Agarose', 'Factor VIII', 'Humans', 'Methods', 'Swine'] | 526,447 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of Ocular Pulse Amplitude Lowering Effects of Preservative-Free Tafluprost and Preservative-Free Dorzolamide-Timolol Fixed Combination Eyedrops. | PURPOSE: To compare the ocular pulse amplitude (OPA) lowering effects of preservative-free tafluprost and dorzolamide-timolol fixed combination (DTFC) using dynamic contour tonometry.METHODS: In total, 66 eyes of 66 patients with normal tension glaucoma (NTG) (n = 34) or primary open angle glaucoma (POAG) (n = 32) were... | ['Drug Combinations', 'Eye', 'Female', 'Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Low Tension Glaucoma', 'Male', 'Middle Aged', 'Ocular Hypertension', 'Ophthalmic Solutions', 'Preservatives, Pharmaceutical', 'Prostaglandins F', 'Retrospective Studies', 'Sulfonamides', 'Thiophenes', 'Timolol', 'Tonometry... | 26,557,671 | [['D26.310'], ['A01.456.505.420', 'A09.371'], ['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['C11.525.381.703', 'C11.640.225'], ['M01.060.116.630'], ['C11.525'], ['D26.776.708.645', 'D27.505.954.578.645', 'D27.720.752.608'], ['D26.650.702', 'D27.720.744.771'], ['D10.251.355.255.550.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Corneal epithelial toxic effects and inflammatory response to perfluorocarbon liquid. | We report an unusual case of corneal epithelial toxic effects associated with perfluorocarbon liquids (PFCLs). The clinical and histopathologic findings are described. An elderly man underwent vitreoretinal surgery for a complicated retinal detachment. Perfluorodecalin was used to repair the retina. It was left in situ... | ['Aged', 'Biopsy', 'Conjunctiva', 'Corneal Ulcer', 'Epithelium, Corneal', 'Fluorocarbons', 'Humans', 'Male', 'Retinal Detachment'] | 10,532,454 | [['M01.060.116.100'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['A09.371.060.200', 'A09.371.337.168'], ['C01.375.177', 'C11.204.564.225', 'C11.294.177'], ['A09.371.060.217.325', 'A10.272.510'], ['D02.455.526.510.435'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Co-ordinator of the health team. | We at the Diabetes Foundation see the general practitioner as the co-ordinator of the community health team. As a branch of this team we rely on the communications and referrals of the general practitioner. | ['Communication', 'Community Health Services', 'Diabetes Mellitus', 'Family', 'Family Practice', 'Foundations', 'Humans', 'Patient Care Team', 'Referral and Consultation'] | 7,337,571 | [['F01.145.209', 'L01.143'], ['N02.421.143'], ['C18.452.394.750', 'C19.246'], ['F01.829.263', 'I01.880.853.150'], ['H02.403.340.500'], ['N03.219.483.311', 'N03.540.630.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.590.715'], ['N04.452.758.849']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
Design and technology in the development of potters' lathes for modeling with terracota: the case of Cabo de Santo Agostinho. | This article reports the experience of the design team of the Laboratory The Imaginary in the process of developing an electric potter's lathe which respects the biomechanics of the body, helps to development the task, maintains the archetype of traditional equipment, and improves the mechanical efficiency of the power... | ['Biomechanical Phenomena', 'Brazil', 'Ceramics', 'Efficiency', 'Electric Power Supplies', 'Equipment Design', 'Ergonomics', 'Humans', 'Musculoskeletal Diseases', 'Occupational Diseases'] | 22,316,890 | [['G01.154.090', 'G01.374.089'], ['Z01.107.757.176'], ['J01.637.153'], ['F02.784.692.351', 'N04.452.209'], ['E07.305.124'], ['E05.320'], ['F02.784.412', 'J01.293.556'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05'], ['C24']] | ['Phenomena and Processes [G]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Tissue plasminogen activator (tPA) as a reporter gene in transient gene expression. | Using the gene coding for tissue plasminogen activator (tPA) as a reporter gene, a transient gene expression system has been established. Vectors containing the full-length cDNA of tPA with its signal sequences were introduced into mammalian recipient cells by a modified gene transfer procedure. Thirty hours after tran... | ['Animals', 'Cell Line', 'DNA Restriction Enzymes', 'Gene Expression Regulation', 'Genes', 'Genetic Vectors', 'L Cells', 'Mice', 'Promoter Regions, Genetic', 'Simian virus 40', 'Tissue Plasminogen Activator', 'Transcription, Genetic', 'Transfection'] | 2,828,192 | [['B01.050'], ['A11.251.210'], ['D08.811.150.280', 'D08.811.277.352.335.350.300', 'D08.811.277.352.355.325.300'], ['G05.308'], ['G05.360.340.024.340'], ['G05.360.337'], ['A11.251.210.505', 'A11.329.228.505'], ['B01.050.150.900.649.313.992.635.505.500'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.02... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transferring dying nursing home residents to the hospital: DON perspectives on the nurse's role in transfer decisions. | This qualitative study elicits factors that influence decision-making by nurses about transferring a dying resident from the nursing home to the hospital. Focus groups with directors of nursing (DONs) from long-term care facilities revealed those decisions are influenced by knowledge (or lack thereof) of resident or fa... | ['Decision Making', 'Focus Groups', 'Hospitalization', 'Humans', 'Managed Care Programs', 'Nurse Administrators', "Nurse's Role", 'Nursing Homes', 'Patient Transfer', 'Physician-Nurse Relations', 'Terminally Ill'] | 11,780,005 | [['F02.463.785.373'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.800', 'N04.590.374.410'], ['M01.526.070.670', 'M01.526.485.650.580', 'N02.360.650.580'], ['F01.829.316.616.625.450', 'N05.30... | ['Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inching Up and Socio-economic Differentiation: Exploring Self-rated Health of China's Rural-to-Urban Migrants from 2005 to 2015. | Objective Large-scale rural-to-urban migration in China has stimulated heated discussion about rural migrants' poor health status. This article reports the first study in China that compares the aggregate-level change in self-rated health of rural migrants between 2005 and 2015, and explores whether the difference, if ... | ['Adult', 'China', 'Cross-Sectional Studies', 'Female', 'Health Status', 'Health Status Disparities', 'Healthcare Disparities', 'Humans', 'Insurance Coverage', 'Male', 'Middle Aged', 'Rural Population', 'Transients and Migrants', 'Urban Population'] | 30,688,646 | [['M01.060.116'], ['Z01.252.474.164'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['N04.590.374.380', 'N05.300.493'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[A case of adolescent adrenoleukodystrophy with clinical improvement after allogeneic bone marrow transplantation (allo-BMT)]. | We reported a case of adolescent type adrenoleukodystrophy. A 20-year old man noticed slight hemiparesis on his right side. After admission, high level of serum VCLFA and ACTH and a point mutation in ALDP codon 606 were recognized along with white matter lesions in the left medulla, basal ganglia, splenium of the corpu... | ['Adrenoleukodystrophy', 'Adult', 'Bone Marrow Transplantation', 'Brain', 'Drug Combinations', 'Erucic Acids', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Transplantation, Homologous', 'Triolein'] | 15,568,481 | [['C10.228.140.163.100.084', 'C10.228.140.163.100.362.250', 'C10.228.140.695.625.250', 'C10.314.400.250', 'C10.597.606.360.455.124', 'C16.320.322.500.124', 'C16.320.400.525.124', 'C16.320.565.189.084', 'C16.320.565.189.362.250', 'C16.320.565.663.100', 'C18.452.132.100.084', 'C18.452.132.100.362.250', 'C18.452.648.189.0... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Conversations About Financial Issues in Routine Oncology Practices: A Multicenter Study. | PURPOSE: To describe the frequency, content, dynamics, and patterns of cost conversations in academic medical oncology across tumor types.PATIENTS AND METHODS: We reviewed 529 audio recordings between May 3, 2012, to September 23, 2014, from a prospective three-site communication study in which patients at any stage of... | ['Communication', 'Female', 'Humans', 'Male', 'Medical Oncology', 'Prospective Studies'] | 31,162,996 | [['F01.145.209', 'L01.143'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.429.515'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Pheochromocytoma with asymmetric septal hypertrophy and Wolff-Parkinson-White syndrome. | A 24-year-old woman with pheochromocytoma associated with asymmetric septal hypertrophy, Wolff-Parkinson-White syndrome and pigmentation was operated on and the tumor was excised. The asymmetric hypertrophy and the pre-excitation disappeared after the operation, but the pigmentation increased. We discuss the relation b... | ['Adrenal Gland Neoplasms', 'Adult', 'Cardiomyopathies', 'Female', 'Heart Septum', 'Humans', 'Pheochromocytoma', 'Pigmentation Disorders', 'Wolff-Parkinson-White Syndrome'] | 1,791,095 | [['C04.588.322.078', 'C19.053.347', 'C19.344.078'], ['M01.060.116'], ['C14.280.238'], ['A07.541.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.700.725', 'C04.557.580.625.650.700.725'], ['C17.800.621', 'C23.550.755'], ['C14.280.067.780.977', 'C14.280.123.750.977', 'C16.131.240.400.980']] | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Autopsied cases of drowning in Denmark 1987-1989. | In the 3-year period 1987-1989, 219 drowning cases were submitted to medico-legal autopsy in Denmark. The demographic data including the manner of death and the external findings are reported. In 74 accident cases analysis for blood-alcohol concentration was performed. In 53% a concentration of more than 0.1% was found... | ['Accidents', 'Adult', 'Age Factors', 'Autopsy', 'Denmark', 'Drowning', 'Ethanol', 'Exudates and Transudates', 'Female', 'Homicide', 'Humans', 'Infant, Newborn', 'Lung', 'Male', 'Middle Aged', 'Organ Size', 'Pleura', 'Postmortem Changes', 'Seasons', 'Suicide'] | 1,783,341 | [['N06.850.135'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['Z01.542.816.124'], ['C23.550.260.393', 'C26.304', 'N06.850.135.696'], ['D02.033.375'], ['A12.383'], ['I01.198.240.470', 'I01.880.735.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and P... | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Inhibition of nitric oxide synthase and soluble guanylate cyclase induces cardiodepressive effects in normal rat hearts. | Exogenous nitric oxide (NO) has been shown to modulate the contractile force of rat cardiac myocytes. We sought to determine whether endogenous NO-production in the isolated normal rat heart has an effect on myocardial contractility. Hearts of male Wistar rats were investigated using a constant flow perfused non-paced ... | ['Animals', 'Coronary Circulation', 'Depression, Chemical', 'Guanylate Cyclase', 'Heart Rate', 'In Vitro Techniques', 'Male', 'Myocardial Contraction', 'Myocardium', 'Nitric Oxide', 'Nitric Oxide Synthase', 'Rats', 'Rats, Wistar', 'Solubility'] | 9,369,347 | [['B01.050'], ['G09.330.100.324'], ['G07.690.773.750'], ['D08.811.520.650.600', 'D12.644.360.350', 'D12.776.476.350'], ['E01.370.600.875.500', 'G09.330.380.500'], ['E05.481'], ['G09.330.580', 'G11.427.494.570'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D0... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Upper esophageal sphincter opening during swallow in stroke survivors. | OBJECTIVE: Timely and efficient upper esophageal sphincter (UES) opening may be critical to safe transport of food or liquid to the stomach and to prevent aspiration during the swallow. The purpose of this study was to examine the temporal and biomechanical characteristics of the UES opening in stroke survivors.METHOD:... | ['Deglutition', 'Deglutition Disorders', 'Esophageal Motility Disorders', 'Esophageal Sphincter, Upper', 'Female', 'Fluoroscopy', 'Follow-Up Studies', 'Humans', 'Male', 'Muscle Contraction', 'Pneumonia, Aspiration', 'Reference Values', 'Risk Assessment', 'Stroke', 'Stroke Rehabilitation', 'Survivors', 'Time Factors', '... | 25,768,066 | [['G10.261.178'], ['C06.405.117.119', 'C09.775.174'], ['C06.405.117.119.500'], ['A02.633.567.800.360', 'A03.556.875.500.360', 'A04.623.617.360', 'A14.724.617.360'], ['E01.370.350.700.225'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.4... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Neuroimaging Feature Terminology: A Controlled Terminology for the Annotation of Brain Imaging Features. | Ontologies and terminologies are used for interoperability of knowledge and data in a standard manner among interdisciplinary research groups. Existing imaging ontologies capture general aspects of the imaging domain as a whole such as methodological concepts or calibrations of imaging instruments. However, none of the... | ['Algorithms', 'Alzheimer Disease', 'Brain', 'Cognitive Dysfunction', 'Computational Biology', 'Databases, Bibliographic', 'Humans', 'Image Processing, Computer-Assisted', 'Natural Language Processing', 'Neuroimaging', 'Terminology as Topic'] | 28,731,430 | [['G17.035', 'L01.224.050'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['A08.186.211'], ['F03.615.250.700'], ['H01.158.273.180', 'L01.313.124'], ['L01.313.500.750.300.188.300', 'L01.470.750.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['L01.224.050.375.580'], ['E01.370.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Quality of life and visual function in children with glaucoma in Spain. | OBJECTIVE: To evaluate the effect of glaucoma on visual function, as well as quality of life in children and quality of life perceived by caregivers in children up to 16 years of age.MATERIAL AND METHODS: An observational and prospective study was designed using the questionnaire GQL-15 (Glaucoma Quality of Life) and c... | ['Child', 'Correlation of Data', 'Female', 'Glaucoma', 'Humans', 'Male', 'Prospective Studies', 'Quality of Life', 'Self Report', 'Spain', 'Vision, Ocular', 'Visual Acuity'] | 30,446,240 | [['M01.060.406'], ['H01.548.832.500'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E05.318.308.980.500', 'N05.715.360.300.800.500', 'N06.850.520.3... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Phe... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Nonimmunologic binding of horseradish peroxidase to hepatitis B surface antigen. A possible source of error in immunohistochemistry. | In the process of establishing the specificity of direct immunoperoxidase staining of liver tissue for hepatitis B surface antigen (HBsAg), an affinity of free horseradish peroxidase (HRP) for HBsAg in hepatocytes (ground-glass cells) was found. Of 95 patients, the horseradish peroxidase reaction was only positive in t... | ['Hepatitis B Surface Antigens', 'Horseradish Peroxidase', 'Humans', 'Immunoenzyme Techniques', 'Liver', 'Peroxidases', 'Staining and Labeling'] | 6,155,065 | [['D23.050.327.495.500.475'], ['D08.811.682.732.512'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.350', 'E05.478.583.400', 'E05.601.470.350'], ['A03.620'], ['D08.811.682.732'], ['E01.370.225.500.620.670', 'E01.370.225.750.600.670', 'E05.200.500.620.670', 'E05.200.750.600.670']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Culling-induced social perturbation in Eurasian badgers Meles meles and the management of TB in cattle: an analysis of a critical problem in applied ecology. | The Eurasian badger (Meles meles) is implicated in the transmission of bovine tuberculosis (TB) to cattle in the UK and Republic of Ireland. Badger culling has been employed for the control of TB in cattle in both countries, with varying results. Social perturbation of badger populations following culling has been prop... | ['Animals', 'Cattle', 'Disease Reservoirs', 'Female', 'Male', 'Motor Activity', 'Mustelidae', 'Mycobacterium bovis', 'Population Dynamics', 'Social Behavior', 'Tuberculosis, Bovine'] | 17,725,974 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['N06.850.520.203.250'], ['F01.145.632', 'G11.427.410.698'], ['B01.050.150.900.649.313.750.250.575'], ['B03.510.024.962.500.402', 'B03.510.460.400.410.552.552.402'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['F01.145.813'], ['C01.150.252.410.040.552.8... | ['Organisms [B]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Down-regulation and differential restoration of cAMP responses upon transient phorbol ester treatment of primary osteoblastic cells. | We studied cAMP responses induced by parathyroid hormone (PTH), prostaglandin E2 (PGE2) and forskolin in foetal rat calvariae-derived osteoblastic cells after 24 h treatment with a protein kinase C (PKC) activating phorbol ester. After this treatment, meant to down-regulate PKC activity, all tested cAMP responses were ... | ['1-Methyl-3-isobutylxanthine', 'Adenylyl Cyclases', 'Animals', 'Cells, Cultured', 'Colforsin', 'Cyclic AMP', 'Dinoprostone', 'Down-Regulation', 'Enzyme Activation', 'Kinetics', 'Osteoblasts', 'Parathyroid Hormone', 'Phorbol Esters', 'Phosphodiesterase Inhibitors', 'Protein Kinase C', 'Rats', 'Receptors, Parathyroid Ho... | 8,588,978 | [['D03.633.100.759.758.824.751.500'], ['D08.811.520.650.200', 'D12.644.360.050', 'D12.776.476.050'], ['B01.050'], ['A11.251'], ['D02.455.849.291.300'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D10.251.355.255.550.250.200', 'D23.469.050.175.725.250.200'], ['G02.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative genomics in cyprinids: common carp ESTs help the annotation of the zebrafish genome. | BACKGROUND: Automatic annotation of sequenced eukaryotic genomes integrates a combination of methodologies such as ab-initio methods and alignment of homologous genes and/or proteins. For example, annotation of the zebrafish genome within Ensembl relies heavily on available cDNA and protein sequences from two distantly... | ['Algorithms', 'Animals', 'Carps', 'Chromosome Mapping', 'Cyprinidae', 'Databases, Nucleic Acid', 'Expressed Sequence Tags', 'Gene Library', 'Genome', 'Genomics', 'Male', 'Sequence Homology, Nucleic Acid', 'Testis', 'Untranslated Regions', 'Zebrafish'] | 17,254,304 | [['G17.035', 'L01.224.050'], ['B01.050'], ['B01.050.150.900.493.200.244.248'], ['E05.393.183'], ['B01.050.150.900.493.200.244'], ['L01.313.500.750.300.188.400.300.500', 'L01.313.500.750.300.188.400.325.630', 'L01.470.750.750.300.500', 'L01.470.750.750.325.630'], ['G05.360.340.024.340.137.275'], ['G05.360.325'], ['G05.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of timing of parental divorce on the vulnerability of children to depression in young adulthood. | The significance of a child's age at parents' divorce on later well-being was studied. In a population-based follow-up study from age 16 to 22, children who had experienced parental divorce before school age (n = 134), in latency at age 7 to 12 (n = 129), and in adolescence at age 13 to 16 (n = 71) were compared. In yo... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Depression', 'Divorce', 'Female', 'Finland', 'Gender Identity', 'Humans', 'Interpersonal Relations', 'Male', 'Personality Development', 'Personality Inventory', 'Risk Factors'] | 7,832,032 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['F01.145.126.350'], ['F01.829.263.315.500.300', 'I01.240.361.500.300', 'I01.880.735.255', 'I01.880.853.150.423.500.300', 'N01.224.361.500.300', 'N01.824.308.500.300'], ['Z01.542.816.186'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.7... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Pregnancy-induced leukocytosis in Yemenite Jews. | Benign neutropenia is often found among healthy Yemenite Jews. An assessment was made of the magnitude of labor-induced leukocytosis in 44 Yemenite Jewish women, by comparing their hematological values during labor with those of 27 non-Yemenite women. A statistically significant difference was found in the absolute cou... | ['Adult', 'Female', 'Humans', 'Hydrocortisone', 'Jews', 'Labor, Obstetric', 'Leukocytosis', 'Leukopenia', 'Neutropenia', 'Pregnancy', 'Pregnancy Complications, Hematologic', 'Yemen'] | 6,410,643 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['M01.686.754.600'], ['G08.686.784.769.326'], ['C15.378.553.475', 'C23.550.526'], ['C15.378.553.546'], ['C15.378.553.546.184.564'], ['G08.686.784.769'], ['C13.703.667... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Genotyping Leishmania promastigotes isolated from patients with cutaneous leishmaniasis in south-eastern Turkey. | Objective Cutaneous leishmaniasis (CL) is a significant disease in south-eastern Anatolia because it is prevalent among Syrian refugees. We identified the causative Leishmania species in CL patients using molecular methods. Methods Novy-MacNeal-Nicolle medium was inoculated with aspirated fluid from suspected CL lesion... | ['Adolescent', 'Adult', 'Azure Stains', 'DNA, Intergenic', 'DNA, Protozoan', 'Female', 'Genotype', 'Humans', 'Leishmania tropica', 'Leishmaniasis, Cutaneous', 'Life Cycle Stages', 'Male', 'Molecular Typing', 'Phylogeny', 'Polymorphism, Restriction Fragment Length', 'Refugees', 'Sequence Analysis, DNA', 'Skin', 'Turkey'... | 28,222,637 | [['M01.060.057'], ['M01.060.116'], ['D02.886.369.080', 'D03.633.300.783.080'], ['D13.444.308.324', 'G05.360.340.024.220'], ['D13.444.308.442'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.268.475.868.488.680'], ['C01.610.752.300.500.400', 'C01.610.858.560.400', 'C01.920.813.400', 'C17.800.838.77... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Inactivation of phosphatidylethanolamine N-methyltransferase-2 in aflatoxin-induced liver cancer and partial reversion of the neoplastic phenotype by PEMT transfection of hepatoma cells. | Phosphatidylethanolamine N-methyltransferase(PEMT) is an enzyme in liver that catalyzes the stepwise methylation of phosphatidylethanolamine to phosphatidylcholine, in addition to the main pathway that synthesizes phosphatidylcholine directly from choline. We have reported that PEMT is permanently inactivated in liver ... | ['Aflatoxins', 'Animals', 'Cell Transformation, Neoplastic', 'Enzyme Activation', 'Gene Expression Regulation, Enzymologic', 'Gene Expression Regulation, Neoplastic', 'Gene Transfer Techniques', 'Genetic Therapy', 'Liver Neoplasms, Experimental', 'Male', 'Methyltransferases', 'Mice', 'Phosphatidylethanolamine N-Methylt... | 10,760,824 | [['D03.383.663.283.119', 'D03.633.100.150.119', 'D23.946.587.142'], ['B01.050'], ['C04.697.098.500', 'C23.550.727.098.500'], ['G02.111.263', 'G03.328'], ['G05.308.320'], ['G05.308.370'], ['E05.393.350'], ['E02.095.301', 'E05.393.420.301'], ['C04.588.274.623.460', 'C04.619.540', 'C06.301.623.460', 'C06.552.697.580', 'E0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Engineering Microbes to Synthesize Plant Isoprenoids. | Humans constantly look for faster, more economical, and more sustainable ways to produce chemicals that originally harvested from nature. Over the past two decades, substantial progress has been made toward this goal by harnessing enzymes and cells as biocatalysts. For example, enzymes of slow-growing plants can be rec... | ['Bioreactors', 'Biosynthetic Pathways', 'Coculture Techniques', 'Escherichia coli', 'Genes, Plant', 'Industrial Microbiology', 'Metabolic Engineering', 'Plants', 'Saccharomyces cerevisiae', 'Terpenes', 'Transformation, Genetic'] | 27,417,931 | [['E07.115', 'J01.897.120.115'], ['G02.111.098', 'G03.493.100'], ['E05.481.500.374'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['H01.158.273.540.460', 'J01.897.120.460'], ['E05.393.420.526', 'E05.481.500.311.249', 'J01.293.069.249.249'], ['B01.650'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Dynamic mechanical analysis of provisional resin materials reinforced by metal oxides. | In this study, several provisional resin materials were investigated by dynamic mechanical analysis (DMA). The materials were autopolymerized PMMA and PEMA, light cured PMMA. Autopolymerized PMMA has the highest T(g) (131 degrees C) compared to that of the autopolymerized PEMA (102 degrees C) and light cured PMMA (120 ... | ['Aluminum Oxide', 'Biomedical Engineering', 'Composite Resins', 'Hot Temperature', 'Magnesium Oxide', 'Metals', 'Methylmethacrylates', 'Models, Chemical', 'Oxides', 'Polymers', 'Polymethyl Methacrylate', 'Pressure', 'Temperature', 'Zinc Oxide'] | 15,911,998 | [['D01.056.050', 'D01.650.550.050'], ['H02.070', 'J01.293.140'], ['D05.750.716.822.308', 'D25.339.816.500', 'D25.720.716.822.308', 'J01.637.051.339.816.500', 'J01.637.051.720.716.822.308'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.... | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Improved sensitivity of glutamine synthetase assay and of acyl hydroxamates. | Sensitivity of glutamine synthetase assay by the hydroxamate method can be doubled by replacing ferric chloride with ferric nitrate of ferric perchlorate, each with the appropriate acid. | ['Absorption', 'Ferric Compounds', 'Glutamate-Ammonia Ligase', 'Hydroxamic Acids', 'Indicators and Reagents', 'Nitrates', 'Perchlorates', 'Spectrophotometry'] | 6,106,903 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['D01.490.100'], ['D08.811.464.259.200.600'], ['D02.092.570.394', 'D02.241.511.372'], ['D27.720.470.410'], ['D01.248.497.158.606', 'D01.625.525.550', 'D02.583'], ['D01.029.260.650', 'D01.210.675'], ['E05.196.712.726', 'E05.196.867.826']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Induction of proline-rich tyrosine kinase2 (Pyk2) through C/EBPbeta is involved in PMA-induced monocyte differentiation. | Proline-rich tyrosine kinase2 (Pyk2) is a cytoplasmic tyrosine kinase related to focal adhesion kinase. Pyk2 expression has been known to be restricted to neuronal and hematopoietic cells and Pyk2 tyrosine phosphorylation and its kinase activity is important for the function of monocytes/macrophages. In NB4 acute promy... | ['CCAAT-Enhancer-Binding Protein-beta', 'Cell Differentiation', 'Focal Adhesion Kinase 2', 'Gene Expression Regulation, Enzymologic', 'HeLa Cells', 'Hematopoiesis', 'Humans', 'MAP Kinase Kinase Kinases', 'Monocytes', 'Promoter Regions, Genetic', 'Tetradecanoylphorbol Acetate', 'Tumor Cells, Cultured', 'Up-Regulation'] | 18,198,130 | [['D12.776.260.108.124.750', 'D12.776.660.167.750', 'D12.776.930.127.124.750'], ['G04.152'], ['D08.811.913.696.620.682.725.049.750', 'D23.050.301.500.600.350', 'D23.050.705.552.600.350'], ['G05.308.320'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['G04.152.825', 'G09.188.343'], ['B01.050.150.900.64... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Vitamin D deficiency is associated with reduced mobility after hip fracture surgery: a prospective study. | BACKGROUND: Hip fractures are associated with a high rate of morbidity and mortality, and successful ambulation after surgery is an important outcome in this patient population.OBJECTIVE: This study aims to determine whether 25-hydroxyvitamin D [25(OH)D] concentration or the Geriatric Nutritional Risk Index (GNRI) is a... | ['Aged', 'Aged, 80 and over', 'Female', 'Hip Fractures', 'Humans', 'Male', 'Prospective Studies', 'Recovery of Function', 'Vitamin D', 'Vitamin D Deficiency'] | 32,073,599 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['G16.757'], ['D04.210.500.812.768'], ['C18.654.521.500.133.770']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Parallel evolution of placentation in Australian scincid lizards. | Viviparity and placental nutrient provision have evolved on numerous occasions in squamate reptiles. Five lineages are substantially placentotrophic and two of these, the genera Pseudemoia and Niveoscincus, are closely related scincid lizards that have independently evolved viviparity and placentation. Histological com... | ['Animals', 'Biological Evolution', 'Chorioallantoic Membrane', 'Female', 'Lizards', 'Placentation', 'Pregnancy', 'Viviparity, Nonmammalian', 'Yolk Sac'] | 19,012,323 | [['B01.050'], ['G05.045', 'G16.075'], ['A10.615.284.375', 'A13.350.575', 'A16.331.400'], ['B01.050.150.900.833.393'], ['G08.686.784.769.491'], ['G08.686.784.769'], ['G08.686.920'], ['A10.615.284.981', 'A16.254.750.981', 'A16.331.800']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Random sequential addition simulations of animal aggregations provide null models of group structure. | Apparent structure in animal aggregations such as fish and Antarctic krill schools may result from the tight packing of these elongated animals. This geometrical structure may be difficult to differentiate from behavior-induced structure resulting from individuals preferentially taking up certain positions relative to ... | ['Animals', 'Behavior, Animal', 'Fishes', 'Models, Biological', 'Swimming'] | 30,818,295 | [['B01.050'], ['F01.145.113'], ['B01.050.150.900.493'], ['E05.599.395'], ['G11.427.410.568.800', 'G11.427.410.698.277.875', 'I03.350.875', 'I03.450.642.845.945.500']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Endogenous testosterone and cortisol jointly influence reactive aggression in women. | The dual-hormone hypothesis posits that the effect of testosterone on social behavior is moderated by cortisol. The present study tested this hypothesis with a competitive reactive aggression paradigm in 53 healthy undergraduate women. Salivary cortisol and testosterone were assessed at baseline. Participants were pers... | ['Adult', 'Affect', 'Aggression', 'Dominance-Subordination', 'Female', 'Humans', 'Hydrocortisone', 'Interpersonal Relations', 'Testosterone'] | 22,854,014 | [['M01.060.116'], ['F01.470.047'], ['F01.145.126.125', 'F01.145.813.045'], ['F01.145.813.650.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['F01.829.401'], ['D04.210.500.054.079.429.824', 'D06.472.334.851.968.984']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Motion makes sense: an adaptive motor-sensory strategy underlies the perception of object location in rats. | Tactile perception is obtained by coordinated motor-sensory processes. We studied the processes underlying the perception of object location in freely moving rats. We trained rats to identify the relative location of two vertical poles placed in front of them and measured at high resolution the motor and sensory variab... | ['Adaptation, Physiological', 'Animals', 'Choice Behavior', 'Discrimination Learning', 'Distance Perception', 'Female', 'Head Movements', 'Motion Perception', 'Physical Stimulation', 'Rats', 'Stereotyped Behavior', 'Touch', 'Touch Perception', 'Vibrissae'] | 26,063,912 | [['G07.025', 'G16.012.500'], ['B01.050'], ['F02.463.785.373.346'], ['F02.463.425.280'], ['F02.463.593.200.390', 'F02.463.593.778.255.390'], ['G11.427.410.478'], ['F02.463.593.932.567'], ['E05.723'], ['B01.050.150.900.649.313.992.635.505.700'], ['F01.145.896'], ['F02.830.816.850', 'G11.561.790.850'], ['F02.463.593.894']... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of triamterene on potassium excretion in cirrhotic patients receiving furosemide. | In a three-way crossover study, 23 patients with hepatic cirrhosis, ascites, and dependent edema received 40 mg/day of furosemide alone and combined with triamterene 50 mg/day and triamterine 100 mg/day. Baseline potassium excretion did not increase when furosemide was given alone, but potassium excretion fell when 50 ... | ['Chlorides', 'Clinical Trials as Topic', 'Drug Therapy, Combination', 'Electrolytes', 'Female', 'Furosemide', 'Humans', 'Liver Cirrhosis', 'Male', 'Potassium', 'Sodium', 'Triamterene'] | 321,176 | [['D01.210.450.150', 'D01.248.497.158.215'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['E02.319.310'], ['D01.248'], ['D02.065.884.725.300', 'D02.092.146.807.300', 'D02.886.590.700.725.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.355.412'], ['D01.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Recruiting and retaining minorities in nursing education. | Increasing nursing education opportunities for individuals from minority and/or disadvantaged backgrounds is the purpose of this project. Activities included the implementation of programs to enhance preentry preparation, retention, cultural competence and financial support. Intense recruitment strategies were targeted... | ['Alabama', 'Career Choice', 'Cultural Diversity', 'Education, Nursing', 'Humans', 'Minority Groups', 'Program Development', 'Training Support'] | 19,927,893 | [['Z01.107.567.875.075.100', 'Z01.107.567.875.750.100'], ['F02.463.785.373.346.400'], ['I01.076.201.450.350', 'I01.880.853.100.450'], ['I02.358.462'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.853.300'], ['N04.452.760'], ['N03.219.483.838']] | ['Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Cytochromes P450 Preferentially Expressed in Antennae of the Mountain Pine Beetle. | The mountain pine beetle (MPB, Dendroctonus ponderosae) is a forest insect pest endemic to western North America. During dispersal and host colonization, MPB identify suitable host trees by olfaction of monoterpene volatiles, contend with host terpene defenses, and communicate with conspecifics using terpenoid and othe... | ['Animals', 'Arthropod Antennae', 'Coleoptera', 'Cytochrome P-450 Enzyme System', 'Fat Body', 'Female', 'Life Cycle Stages', 'Male', 'Pheromones', 'RNA', 'Smell', 'Transcriptome'] | 30,043,088 | [['B01.050'], ['A13.093'], ['B01.050.500.131.617.720.500.500.375'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['A13.365'], ['B05.500', 'G07.345.500.550.500'], ['D23.641'], ['D13.444.735'], ['F02.830.816.643', 'G11.561.790.643'], ['G02.111.873.750', 'G05.297.700.750', 'G05.360.920']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Morbidity and mortality of craniotomy for excision of supratentorial gliomas. | Extensive surgical resection of supratentorial gliomas increases survival. However, some reports suggest that the perioperative morbidity and mortality outweigh the potential benefit of the procedure. We examined prospectively morbidity and mortality in 104 consecutive patients who underwent surgery for supratentorial ... | ['Adult', 'Aged', 'Brain Neoplasms', 'Craniotomy', 'Female', 'Glioma', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications'] | 3,412,585 | [['M01.060.116'], ['M01.060.116.100'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E04.525.190'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Tightly-regulated suicide gene expression kills PSA-expressing prostate tumor cells. | We have previously shown that a dual system for controlling gene expression that relies both on transcriptional regulation and DNA recombination mediated by the site-directed recombinase, Flp, effectively controls the expression of a gene encoding diphtheria toxin (DT-A). In this study, we investigated the use of a chi... | ['Adenoviridae', 'Animals', 'Biomarkers, Tumor', 'Cell Line, Tumor', 'DNA Nucleotidyltransferases', 'Diphtheria Toxin', 'Gene Expression Regulation', 'Genetic Therapy', 'Genetic Vectors', 'Humans', 'Male', 'Mice', 'Mice, Mutant Strains', 'Neoplasm Metastasis', 'Neoplasm Transplantation', 'Peptide Fragments', 'Promoter ... | 16,034,457 | [['B04.280.030'], ['B01.050'], ['D23.101.140'], ['A11.251.210.190', 'A11.251.860.180'], ['D08.811.913.696.445.308'], ['D08.811.913.400.725.115.220', 'D23.946.123.305'], ['G05.308'], ['E02.095.301', 'E05.393.420.301'], ['G05.360.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.50... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Patient Perceptions of Illness Identity in Cancer Clinical Trial Decision-Making. | When patients are diagnosed with cancer, they begin to negotiate their illness identity in relation to their past and future selves, their relationships, and their group memberships. Thus, how patients view their cancer in relation to their other identities may affect how and why they make particular decisions about tr... | ['Adult', 'Clinical Trials as Topic', 'Communication', 'Decision Making', 'Family', 'Female', 'Grounded Theory', 'Humans', 'Middle Aged', 'Neoplasms', 'Patient Participation', 'Perception'] | 28,622,019 | [['M01.060.116'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['F01.145.209', 'L01.143'], ['F02.463.785.373'], ['F01.829.263', 'I01.880.853.150'], ['H01.770.644.241.424'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04'], ['F01.100.150.750.500.620', 'F01.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Do Palliative Care Clinics Screen for Substance Abuse and Diversion? Results of a National Survey. | BACKGROUND: Opioids are the mainstay of treatment of cancer pain. With increased use there have been concerns about rising rates of prescription drug abuse and diversion. Although there has been an increase in research and practice guidelines about the scope of the problem for chronic, nonmalignant pain, less informati... | ['Humans', 'Organizational Policy', 'Pain', 'Palliative Care', 'Palliative Medicine', 'Prescription Drug Diversion', 'Risk Factors', 'Substance Abuse Detection', 'Substance-Related Disorders', 'Surveys and Questionnaires', 'United States'] | 26,302,425 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.655.500.550', 'I01.880.604.825.550', 'N03.623.500.550'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E02.760.666', 'N02.421.585.666'], ['H02.403.645'], ['I01.198.240.609', 'I01.880.735.191.204'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', ... | ['Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Viral load in asymptomatic patients with CD4+ lymphocyte counts above 500 x 10(6)/l. | BACKGROUND: HIV-1-infected patients with a CD4+ lymphocyte count > or = 500 x 10(6)/l may be selected for antiretroviral treatment when viral load is above a given cut-off point.OBJECTIVES: To assess the stability of viral load measurement at CD4+ T-cell counts above 500 x 10(6)/l, and the proportion of patients select... | ['Adult', 'CD4 Lymphocyte Count', 'Female', 'HIV Infections', 'HIV-1', 'Humans', 'Male', 'RNA, Viral', 'Viral Load', 'Viremia'] | 9,110,075 | [['M01.060.116'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.500.150', 'G04.140.107.595.500.150', 'G09.188.105.595.500.150'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Bifidobacteria isolated from vaginal and gut microbiomes are indistinguishable by comparative genomics. | Bifidobacteria colonize the human gastrointestinal tract, vagina, oral cavity and breast milk. They influence human physiology and nutrition through health-promoting effects, play an important role as primary colonizers of the newborn gut, and contribute to vaginal microbiome homeostasis by producing lactic acid. Never... | ['Adult', 'Bacterial Typing Techniques', 'Bifidobacterium', 'Female', 'Gastrointestinal Microbiome', 'Gastrointestinal Tract', 'Genome, Bacterial', 'Genomics', 'Humans', 'Infant, Newborn', 'Milk, Human', 'Mother-Child Relations', 'Phylogeny', 'Sequence Analysis, DNA', 'Vagina'] | 29,684,056 | [['M01.060.116'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['B03.510.024.100', 'B03.510.460.400.400.049.100'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['A03.556'], ['G05.360.340.358.207'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['B01.050.150.900.649.313.988... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 |
Effect of Nasal CPAP on SIRT1 and Endothelial Function in Obstructive Sleep Apnea Syndrome. | BACKGROUND: Sirtuin 1 (SIRT1), a histone/protein deacetylase, has been implicated in aging, metabolism, and stress resistance. SIRT1 regulates endothelial nitric oxide (NO) synthase, restores NO availability, and is involved in different aspects of cardiovascular disease. The aim of this study was to evaluate any abnor... | ['Adult', 'Case-Control Studies', 'Continuous Positive Airway Pressure', 'Endothelium, Vascular', 'Female', 'Humans', 'Male', 'Middle Aged', 'Nitric Oxide', 'Polysomnography', 'Prospective Studies', 'Sirtuin 1', 'Sleep Apnea, Obstructive'] | 26,345,325 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E02.041.625.790.259', 'E02.880.820.790.259'], ['A07.015.700.500', 'A10.272.491.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.55... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular microbial diversity of an anaerobic digestor as determined by small-subunit rDNA sequence analysis. | The bacterial community structure of a fluidized-bed reactor fed by vinasses (wine distillation waste) was analyzed. After PCR amplification, four small-subunit (SSU) rDNA clone libraries of Bacteria, Archaea, Procarya, and Eucarya populations were established. The community structure was determined by operational taxo... | ['Bacteria, Anaerobic', 'Base Composition', 'Biofilms', 'Bioreactors', 'Clone Cells', 'Cloning, Molecular', 'DNA, Bacterial', 'Fermentation', 'Gene Library', 'Molecular Sequence Data', 'Phylogeny', 'Polymerase Chain Reaction', 'RNA, Ribosomal', 'Sequence Analysis, DNA', 'Wine'] | 9,212,428 | [['B03.130'], ['G02.111.080'], ['A20.593', 'G06.120'], ['E07.115', 'J01.897.120.115'], ['A11.251.353'], ['E05.393.220'], ['D13.444.308.212'], ['G02.111.158.249', 'G03.191.249'], ['G05.360.325'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.620.500'], ['D13.444.735.686'], ['E05.393.760.700']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Presentation of medical guidelines on a computer. | Free-text forms of medical guidelines that are used in medical care are often cumbersome and difficult to memorize. Therefore a system that is able to present guidelines in a user-friendly manner has been designed. Guidelines are at first formalized by means of the popular GLIF3 model. Subsequently, the GLIF3 model is ... | ['Decision Support Systems, Clinical', 'Humans', 'Interinstitutional Relations', 'Practice Guidelines as Topic', 'Programming Languages', 'User-Computer Interface'] | 15,718,605 | [['L01.313.500.750.300.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.822.400'], ['N04.761.700.350.650', 'N05.700.350.650'], ['L01.224.900.780'], ['L01.224.900.910']] | ['Information Science [L]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Nonspecific protease-catalyzed hydrolysis/synthesis of a mixture of peptides: product diversity and ligand amplification by a molecular trap. | We sought to develop a peptide library in solution and dynamically screen this library for peptides that would bind to macromolecules of interest. Peptide diversity was achieved in an initial stock solution of peptides by using proteases under conditions in which both hydrolysis and synthesis occurred. As an example, a... | ['Chromatography, High Pressure Liquid', 'Endopeptidases', 'Fibrinogen', 'Hydrolysis', 'Ligands', 'Peptides', 'Protein Binding'] | 9,140,201 | [['E05.196.181.400.300'], ['D08.811.277.656.300'], ['D12.776.124.050.250', 'D12.776.124.125.500', 'D12.776.811.300', 'D23.119.490'], ['G02.380'], ['D27.720.470.480'], ['D12.644'], ['G02.111.679', 'G03.808']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Estimation and interpretation of heterogeneous vaccine efficacy against recurrent infections. | Vaccine-induced protection may not be homogeneous across individuals. It is possible that a vaccine gives complete protection for a portion of individuals, while the rest acquire only incomplete (leaky) protection of varying magnitude. If vaccine efficacy is estimated under wrong assumptions about such individual level... | ['Bias', 'Humans', 'Infections', 'Models, Statistical', 'Recurrence', 'Treatment Outcome', 'Vaccines'] | 26,788,860 | [['N05.715.350.150', 'N06.850.490.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['C23.550.291.937'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['D20.215.894']] | ['Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of gas condition on acetic acid fermentation by Clostridium thermocellum and Moorella thermoacetica (C. thermoaceticum). | Fermentation with acetogens can be affected by cultivation gas phase, but to date, there is not enough evidence on that matter for Clostridium thermocellum and Moorella thermoacetica. In this work, the effects of sparged CO2 as well as sparged and non-sparged N2 on these microorganisms were studied using glucose and ce... | ['Acetic Acid', 'Anaerobiosis', 'Carbon Dioxide', 'Cellobiose', 'Clostridium thermocellum', 'Coculture Techniques', 'Fermentation', 'Gases', 'Glucose', 'Hydrogen', 'Moorella', 'Nitrogen'] | 28,631,221 | [['D02.241.081.018.165', 'D10.251.400.045.500'], ['G02.111.062', 'G03.078'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['D09.698.365.180.180', 'D09.698.629.305.200', 'D09.947.750.200'], ['B03.300.390.400.200.770', 'B03.353.625.375.500.770', 'B03.510.415.400.200.770'], ['E05.481.500.374'], ['G02.111.158.249', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Osmotic regulation of vasopressin and renin in spontaneously hypertensive rats. | Abnormalities in the vasopressin and renin systems have been reported in spontaneously hypertensive rats (SHR). Therefore, studies were performed to evaluate the responsiveness of these systems to changes in plasma osmolality and sodium concentration. These variables were manipulated in vivo by intraperitoneal administ... | ['Age Factors', 'Animals', 'Culture Techniques', 'Hypertension', 'Hypothalamus', 'Hypotonic Solutions', 'Isotonic Solutions', 'Kidney', 'Male', 'Osmolar Concentration', 'Rats', 'Rats, Inbred SHR', 'Rats, Inbred WKY', 'Renin', 'Saline Solution, Hypertonic', 'Sodium', 'Vasopressins'] | 3,311,989 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['E05.481.500'], ['C14.907.489'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['D26.776.399'], ['D26.776.498'], ['A05.810.453'], ['G02.640'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.300', 'B01.050.150.900.649.313.992.635.505.70... | ['Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Chronic intrinsic transient tracheal occlusion elicits diaphragmatic muscle fiber remodeling in conscious rodents. | BACKGROUND: Although the prevalence of inspiratory muscle strength training has increased in clinical medicine, its effect on diaphragm fiber remodeling is not well-understood and no relevant animal respiratory muscle strength training-rehabilitation experimental models exist. We tested the postulate that intrinsic tra... | ['Animals', 'Breathing Exercises', 'Diaphragm', 'Hypertrophy', 'Male', 'Microscopy, Fluorescence', 'Models, Animal', 'Muscle Strength', 'Muscles', 'Physical Conditioning, Animal', 'Rats', 'Rats, Sprague-Dawley', 'Respiration'] | 23,133,678 | [['B01.050'], ['E02.190.525.186', 'E02.779.474.124'], ['A02.633.567.900.300'], ['C23.300.775'], ['E01.370.350.515.458', 'E05.595.458'], ['E05.598'], ['E01.370.600.425', 'G11.427.560'], ['A02.633', 'A10.690'], ['G11.427.410.698.277.280'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lung CT for detection of metastases: solid tissue neoplasms in children. | The results of 73 computed tomographic studies of lung and pleura in 52 children with solid-tissue tumors have been analyzed. In nine children computed tomography provided information not evident by chest radiograph or whole lung tomography. In four of these cases computed tomography demonstrated lung nodules not seen ... | ['Child', 'Humans', 'Lung', 'Lung Neoplasms', 'Osteosarcoma', 'Respiration', 'Tomography, X-Ray Computed'] | 6,981,971 | [['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.557.450.565.575.650', 'C04.557.450.795.620'], ['G09.772.705'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.810.810', 'E01.37... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Percutaneous electrochemotherapy in the treatment of portal vein tumor thrombosis at hepatic hilum in patients with hepatocellular carcinoma in cirrhosis: A feasibility study. | AIM: To treated with electrochemotherapy (ECT) a prospective case series of patients with liver cirrhosis and Vp3-Vp4- portal vein tumor thrombus (PVTT) from hepatocellular carcinoma (HCC), in order to evaluate the feasibility, safety and efficacy of this new non thermal ablative technique in those patients.METHODS: Si... | ['Aged', 'Aged, 80 and over', 'Carcinoma, Hepatocellular', 'Electrochemotherapy', 'Feasibility Studies', 'Female', 'Humans', 'Liver Cirrhosis', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Portal Vein', 'Prospective Studies', 'Treatment Outcome', 'Venous Thrombosis'] | 28,223,736 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E02.319.341', 'E05.200.500.454.500', 'E05.242.448.500', 'E05.301.500.500'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['B01.050.150.900.649.3... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Regulated unmasking of in vivo synthesized maternal mRNA at oocyte maturation. A role for the chaperone nucleoplasmin. | We examine the translational regulation of histone H4 mRNA when Xenopus laevis oocytes are induced to mature with progesterone. Histone H4 mRNA synthesized from plasmid templates microinjected into oocyte nuclei is translationally silenced (masked). This masked mRNA becomes translationally active only after oocyte matu... | ['Amino Acid Sequence', 'Animals', 'Female', 'Histones', 'Models, Chemical', 'Molecular Sequence Data', 'Nuclear Proteins', 'Nucleoplasmins', 'Oocytes', 'Phosphoproteins', 'Protein Biosynthesis', 'RNA, Messenger', 'Transcription, Genetic', 'Ultraviolet Rays', 'Xenopus laevis'] | 9,139,745 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['E05.599.495'], ['L01.453.245.667'], ['D12.776.660'], ['D12.776.580.219.500'], ['A05.360.490.690.680', 'A11.497.497.600'], ['D12.776.744'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['D... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Unusually high phosphodiesterolytic activity of La(III) hydroxide complexes stabilized by glycine derivatives. | Glycine and N,N-dimethylglycine stabilize La(III) hydroxide complexes of the type La2L2(OH)4 which possess phosphodiesterolytic activity close to that observed with most active tetravalent cations like Ce(IV). | ['Cations', 'Cerium', 'Glycine', 'Hydrogen-Ion Concentration', 'Hydrolysis', 'Kinetics', 'Lanthanum', 'Ligands', 'Molecular Structure', 'Organophosphates', 'Stereoisomerism'] | 12,932,057 | [['D01.248.497.300'], ['D01.268.558.362.249', 'D01.552.550.399.249'], ['D12.125.481'], ['G02.300'], ['G02.380'], ['G01.374.661', 'G02.111.490'], ['D01.268.558.362.500', 'D01.552.550.399.500'], ['D27.720.470.480'], ['G02.111.570', 'G02.466'], ['D02.705.400'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A postgraduate experience at the ASN's annual meeting]. | The annual meeting of the American Society of Nephrology (ASN) is one of the most important conferences in this field. It has a high scientific quality and it receives thousands of participants from all over the world. In this paper, a fellow in Nephrology describes her attendance to this meeting. Moreover, two topics ... | ['Congresses as Topic', 'Nephrology', 'Polycystic Kidney, Autosomal Dominant', 'Societies, Medical', 'Thrombotic Microangiopathies', 'United States'] | 24,671,834 | [['N03.540.199'], ['H02.403.429.580'], ['C12.777.419.403.875.500', 'C13.351.968.419.403.875.500', 'C16.131.077.717.500', 'C16.320.184.625.500'], ['N03.540.828.589'], ['C15.378.140.855.925'], ['Z01.107.567.875']] | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Immunolocalization of nucleolar proteins during bovine oocyte growth, meiotic maturation, and fertilization. | During the growth phase of the bovine oocyte transcripts, polypeptides and ribosomes are accumulated in the oocyte to drive and sustain future meiotic maturation, fertilization, and early embryonic development. The oocyte also furnishes the early embryo with the components required to establish a functional transcripti... | ['Animals', 'Cattle', 'Cell Nucleolus', 'Cell Nucleus', 'Chromosomal Proteins, Non-Histone', 'DNA Topoisomerases, Type I', 'DNA-Binding Proteins', 'Female', 'Fertilization in Vitro', 'Male', 'Meiosis', 'Microscopy, Confocal', 'Nuclear Proteins', 'Oocytes', 'Phosphoproteins', 'Pol1 Transcription Initiation Complex Prote... | 11,319,160 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['A11.284.430.106.279.345.175'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D12.776.660.235', 'D12.776.664.235'], ['D08.811.399.403.483', 'D12.776.157.687.375', 'D12.776.660.720.375'], ['D12.776.260'], ['E02.875.800.750', 'E05.820.800.750'], ['G04.144.22... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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