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Human pentastomiasis: a case report. | We report a case of human pentastomiasis in a 55-year-old farmer whose diagnosis was made incidentally during laparotomy on account of a mechanical small intestinal obstruction caused by adhesions. Encysted parasites and degenerative granulomas were found in the omentum and in the subserosal layer of the small intestin... | ['Animals', 'Arthropods', 'Diagnosis, Differential', 'Humans', 'Intestinal Obstruction', 'Male', 'Middle Aged', 'Parasitic Diseases', 'Zoonoses'] | 16,918,194 | [['B01.050'], ['B01.050.500.131'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.531'], ['M01.060.116.630'], ['C01.610'], ['C01.973', 'C22.969']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Clinical analysis of reexpansion pulmonary edema. | Twenty-one of 146 cases of spontaneous pneumothorax that were treated by thoracentesis or continuous low negative pressure suction drainage (-12 cm H2O) of the pleural space developed REPE. The rate of REPE was higher in patients 20 to 39 years of age than in those over the age of 40, and the rate progressively increas... | ['Adult', 'Aged', 'Female', 'Humans', 'Lung', 'Male', 'Middle Aged', 'Pleura', 'Pneumothorax', 'Pulmonary Edema', 'Suction', 'Thoracostomy'] | 1,959,396 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.411'], ['M01.060.116.630'], ['A04.716', 'A10.615.789.736'], ['C08.528.778'], ['C08.381.742'], ['E04.237.890'], ['E04.579.918', 'E04.928.755']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Expression of the costimulatory molecule B7/BB1 in autoimmune thyroid disease. | Efficient antigen presentation requires the provision of a costimulatory signal, the best characterized of which is B7/BB1. It is unclear whether thyroid cells expressing class II molecules can present autoantigens to T cells, although this has been suggested as an important mechanism in the initiation of Graves' disea... | ['Antigens, CD', 'B-Lymphocytes', 'B7-1 Antigen', 'Cell Line, Transformed', 'Flow Cytometry', 'Fluorescent Antibody Technique', 'Goiter, Nodular', 'Graves Disease', 'Humans', 'Lymphocyte Activation', 'Thyroid Gland', 'Thyroiditis, Autoimmune'] | 7,516,083 | [['D23.050.301.264.035', 'D23.101.100.110'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D12.776.467.150.100', 'D12.776.543.095.100', 'D23.050.301.285.100', 'D23.529.168.100'], ['A11.251.210.172'], ['E01.370.225.500.363.342', 'E01.370.225.50... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Calcium/calmodulin‑dependent protein kinase II enhances metastasis of human gastric cancer by upregulating nuclear factor‑êB and Akt‑mediated matrix metalloproteinase‑9 production. | Calcium/calmodulin‑dependent protein kinase II (CaMKII) is a multi-functional serine/threonine protein kinase, involved in processes that cause tumor progression, including cell cycle regulation, apoptosis and differentiation. However, the role of CaMKII in cancer cell metastasis has not been fully elucidated. In the p... | ['Calcium-Calmodulin-Dependent Protein Kinase Type 2', 'Cell Line, Tumor', 'Enzyme Induction', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lymphatic Metastasis', 'Matrix Metalloproteinase 9', 'NF-kappa B', 'Proto-Oncogene Proteins c-akt', 'Stomach Neoplasms', 'Up-Regulation'] | 25,174,603 | [['D08.811.913.696.620.682.700.125.200', 'D12.644.360.100.200', 'D12.776.476.100.200'], ['A11.251.210.190', 'A11.251.860.180'], ['G05.308.320.200'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.650.560', 'C23.550.727.650.560'], ['D08.811.277.656.300.480.205.360', 'D08.811.277.656.300.480.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sample size determination for the current strategy in oncology Phase 3 trials that tests progression-free survival and overall survival in a two-stage design framework. | The selection of progression-free survival (PFS) or overall survival (OS) as the most suitable primary endpoint (PE) in oncology Phase 3 trials is currently under intense debate. Because of substantial limitations in the single use of PFS (or OS) as the PE, trial designs that include PFS and OS as co-primary endpoints ... | ['Antineoplastic Agents', 'Clinical Trials, Phase III as Topic', 'Computer Simulation', 'Humans', 'Medical Oncology', 'Neoplasms', 'Progression-Free Survival', 'Randomized Controlled Trials as Topic', 'Sample Size', 'Survival Rate'] | 28,886,305 | [['D27.505.954.248'], ['E05.318.372.250.250.220', 'N05.715.360.330.250.250.220', 'N06.850.520.450.250.250.220'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.429.515'], ['C04'], ['E01.789.800.285', 'E05.318.740.998.738', 'N04.761.559.590.800.474', 'N05.715.360.575.575.800.474', 'N05.715.3... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain. | TYK2 is a nonreceptor tyrosine kinase involved in adaptive and innate immune responses. A deactivating coding variant has previously been shown to prevent receptor-stimulated activation of this kinase and provides high protection from several common autoimmune diseases but without immunodeficiency. An agent that recapi... | ['Animals', 'Autoimmunity', 'Female', 'Healthy Volunteers', 'Heterocyclic Compounds', 'Humans', 'Interferon alpha-2', 'Mice', 'Mice, Inbred C57BL', 'Mice, SCID', 'Protein Kinase Inhibitors', 'Signal Transduction', 'TYK2 Kinase'] | 31,341,059 | [['B01.050'], ['G12.450.192'], ['M01.774.500', 'M01.955.236'], ['D03'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890.250.500', 'D12.776.467.374.440.890.250.500', 'D23.529.374.440.890.250.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.64... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Feasibility of fluorescence-guided resection of recurrent gliomas using five-aminolevulinic acid: retrospective analysis of surgical and neurological outcome in 58 patients. | Five-aminolevulinic-acid (5-ALA) is known for its benefits in surgery of primary gliomas, but has only been cautiously used in recurrent gliomas dreading over-resection, insufficient or false-positive fluorescence in adjuvantly treated tumors. We evaluated intraoperative fluorescence based on tumor pathology, pretreatm... | ['Adult', 'Aged', 'Aminolevulinic Acid', 'Brain Neoplasms', 'Case-Control Studies', 'Feasibility Studies', 'Female', 'Fluorescence', 'Follow-Up Studies', 'Glioma', 'Humans', 'Image Processing, Computer-Assisted', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Nervous System Diseases', 'Neuron... | 25,557,106 | [['M01.060.116'], ['M01.060.116.100'], ['D02.241.755.547.276', 'D12.125.262'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['G01.358.500.505... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Role of interleukin 6 in the inflammatory response after cataract surgery. An experimental and clinical study. | The mechanism of uveitis following cataract surgery, which is mediated in part by the cyclooxygenase pathway, is complex, the complexity of which is likely to be due to several factors. We investigated the possible local involvement of interleukin 6 (IL-6) in this response. Using a specific bioassay, we showed a dramat... | ['Animals', 'Anterior Chamber', 'Aqueous Humor', 'Biological Assay', 'Cataract Extraction', 'Cell Movement', 'Humans', 'Injections', 'Interleukin-6', 'Leukocyte Count', 'Male', 'Punctures', 'Rabbits', 'Uveitis'] | 1,841,575 | [['B01.050'], ['A09.371.060.067'], ['A09.371.060.067.070', 'A12.207.270.040'], ['E05.091'], ['E04.540.825.249'], ['G04.198', 'G07.568.500.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['E01.370.225.500.195.107.... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of benzylic hydroxyl substitution on the alpha-adrenoceptor blocking activity of tolazoline. | The R(-)- and S(+)-enantiomers of alpha-hydroxytolazoline, the benzylic hydroxy-substituted derivative of the alpha-adrenoceptor antagonist, tolazoline, were evaluated at alpha 1- and alpha 2-adrenoceptors in canine saphenous vein. Benzylic hydroxyl substitution of tolazoline in either the R(-) or S(+) configuration si... | ['Adrenergic beta-Antagonists', 'Animals', 'Dogs', 'Female', 'Male', 'Stereoisomerism', 'Tolazoline'] | 2,906,294 | [['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['G02.607.445.682'], ['D03.383.129.308.436.750']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determinants of the transmembrane distribution of chloride in rat lymphocytes: role of Cl(-)-HCO3- exchange. | The purpose of the present experiments was to establish the factors that determine the intracellular Cl- concentration ([Cl-]i) of lymphocytes. Coulometric and isotope equilibration determinations indicated that [Cl-]i was in the range of 70-85 mmol/l cells. Since the membrane potential (Em) of these cells approximates... | ["4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid", "4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid", 'Animals', 'Bicarbonates', 'Biological Transport, Active', 'Bumetanide', 'Cell Membrane', 'Chlorides', 'Furosemide', 'Ionophores', 'Kinetics', 'Lymphocytes', 'Male', 'Mathematics', 'Rats', 'Rats, Inbred St... | 2,163,199 | [['D02.455.426.559.389.150.700.200', 'D02.500.375.125', 'D02.886.250.125'], ['D02.455.426.559.389.150.700.050', 'D02.500.375.050', 'D02.886.250.050'], ['B01.050'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['G03.143.310'], ['D02.065.884.150', 'D02.241.223.100.050.300.200', 'D02.455.426.559.389.127.020.452.500... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Does acetylcholine change the electrical resistance of the basal membrane of secretory cells in eccrine sweat glands? | The present experiment was intended to study whether or not acetylcholine decreases the electrical resistance of the basal membrane of secretory cells in stimulating eccrine secretion of fluid and electrolytes. An isolated segment of the secretory coil of the monkey palm eccrine sweat gland was dissected out in vitro a... | ['Acetylcholine', 'Animals', 'Biological Transport, Active', 'Eccrine Glands', 'Electric Conductivity', 'Electric Stimulation', 'Haplorhini', 'In Vitro Techniques', 'Macaca mulatta', 'Membrane Potentials', 'Potassium', 'Sodium', 'Sweat Glands'] | 100,601 | [['D02.092.211.111'], ['B01.050'], ['G03.143.310'], ['A10.336.899.480', 'A17.815.830.480'], ['G01.358.500.249.277'], ['E05.723.402'], ['B01.050.150.900.649.313.988.400'], ['E05.481'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['D01.268.549.550', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Elevated basal progesterone levels are associated with increased preovulatory progesterone rise but not with higher pregnancy rates in ICSI cycles with GnRH antagonists. | OBJECTIVE: To ascertain the association between basal progesterone (P) levels and the occurrence of preovulatory progesterone rise (PPR) and clinical pregnancy rates (CPRs) in ICSI cycles with GnRH antagonists.STUDY DESIGN: Serum P levels of 464 patients were measured on day 2 and day of hCG of cycles. Cycles with basa... | ['Adult', 'Female', 'Gonadotropin-Releasing Hormone', 'Hormone Antagonists', 'Humans', 'Infertility, Female', 'Ovulation', 'Pregnancy', 'Pregnancy Rate', 'Progesterone', 'Prospective Studies', 'Sperm Injections, Intracytoplasmic', 'Treatment Outcome'] | 28,715,660 | [['M01.060.116'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['D06.347', 'D27.505.696.399.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C13.351.500.365.700'], ['G08.686.784.690'], ['G08.686.784.769'], ['E05.318.308.985... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ventilation of patients with acute lung injury and acute respiratory distress syndrome: has new evidence changed clinical practice? | OBJECTIVES: A recent randomized trial of mechanical ventilation in acute lung injury (ALI)/adult respiratory distress syndrome (ARDS) demonstrated a 22% relative reduction in mortality rate using 6 mL/kg predicted body weight tidal volume vs. 12 mL/kg predicted body weight tidal volume. We determined whether publicatio... | ['Female', 'Humans', 'Male', 'Middle Aged', 'Respiration, Artificial', 'Respiratory Distress Syndrome', 'Retrospective Studies', 'Tidal Volume'] | 15,187,503 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.041.625', 'E02.365.647.729', 'E02.880.820'], ['C08.381.840', 'C08.618.840'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.5... | ['Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Apoptosis induction by SAHA in cutaneous T-cell lymphoma cells is related to downregulation of c-FLIP and enhanced TRAIL signaling. | Suberoylanilide hydroxamic acid (SAHA) has been approved for the treatment of cutaneous T-cell lymphoma (CTCL), but its mode of action remained largely elusive. As shown here in four CTCL cell lines, loss of cell viability correlated with significant time- and dose-dependent induction of apoptosis, whereas cytotoxicity... | ['Aged', 'Aged, 80 and over', 'Antineoplastic Agents', 'CASP8 and FADD-Like Apoptosis Regulating Protein', 'Down-Regulation', 'Female', 'Humans', 'Hydroxamic Acids', 'Inhibitor of Apoptosis Proteins', 'Lymphoma, T-Cell, Cutaneous', 'Male', 'Middle Aged', 'Signal Transduction', 'Skin Neoplasms', 'TNF-Related Apoptosis-I... | 22,551,975 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.248'], ['D12.644.360.024.285.024', 'D12.644.360.024.500.024', 'D12.644.360.075.421.024', 'D12.776.157.057.018.024', 'D12.776.476.075.421.024'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.092.570.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparison of Two Models of Frailty for the Prediction of Mortality in Brazilian Community-Dwelling Older Adults: The FIBRA Study. | BACKGROUND: Prevalence of frailty is significant in Latin America. However, no previous study evaluated mortality prediction using the two most used frailty models in Brazil.OBJECTIVES: The aim of the present study was to compare the frailty phenotype and the frailty index with regard to accuracy in the prediction of m... | ['Aged', 'Aged, 80 and over', 'Brazil', 'Cohort Studies', 'Female', 'Frailty', 'Humans', 'Independent Living', 'Longitudinal Studies', 'Male', 'Prevalence', 'Prospective Studies', 'Research Design', 'Survival Rate'] | 31,781,731 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.107.757.176'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C23.550.359'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I03.050.500', 'N01.224.791.550', 'N06.850.505.400.800.550'], ['E05.318.372.500.750.500', 'N05.715.360.330... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
[Pulmonary artery banding using expanded polytetrafluoroethylene suture]. | Pulmonary artery banding (PAB) is essential for infants of complicated cardiac anomaly without pulmonary stenosis, especially those who require future Fontan type correction. In order to avoid pulmonary artery branch stenosis or uneven growth we utilize expanded polytetrafluoroethylene (E-PTFE) suture (Gore-Tex suture,... | ['Female', 'Heart Defects, Congenital', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Polytetrafluoroethylene', 'Pulmonary Artery', 'Suture Techniques', 'Sutures'] | 8,721,359 | [['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['D05.750.395.616', 'D25.720.395.616', 'J01.637.051.720.395.616'], ['A07.015.114.715'], ['E04.987.775'], ['E07.858.690.820']] | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Increased prevalence and coincidence of antinuclear and antithyroid antibodies in the population exposed to high levels of polychlorinated pollutants cocktail. | OBJECTIVES: Because of well known association between the exposure to persistent organochlorinated pollutants (POPs) and impaired immune system, it was attempted to check possible coincidence of nuclear and thyroperoxidase antibodies with the levels of major POPs.METHODS: Antinuclear antibodies. (ANA) were estimated by... | ['Adult', 'Aged', 'Antibodies, Antinuclear', 'Autoantibodies', 'Autoantigens', 'Autoimmune Diseases', 'Cohort Studies', 'Environmental Pollutants', 'Female', 'Humans', 'Iodide Peroxidase', 'Iron-Binding Proteins', 'Male', 'Middle Aged', 'Polychlorinated Biphenyls', 'Slovakia', 'Young Adult'] | 19,856,712 | [['M01.060.116'], ['M01.060.116.100'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D23.050.422'], ['C20.111'], ['E05.318.372.500.750', 'N05.715.360.330.500.750'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Targeted Diet Modification Reduces Multiple Sclerosis-like Disease in Adult Marmoset Monkeys from an Outbred Colony. | Experimental autoimmune encephalomyelitis (EAE) in common marmosets is a translationally relevant model of the chronic neurologic disease multiple sclerosis. Following the introduction of a new dietary supplement in our purpose-bred marmoset colony, the percentage of marmosets in which clinically evident EAE could be i... | ['Animals', 'Apoptosis', 'Bifidobacterium', 'Brain', 'Callithrix', 'Cells', 'Cells, Cultured', 'Demyelinating Diseases', 'Diet Therapy', 'Dietary Supplements', 'Disease Models, Animal', 'Encephalomyelitis, Autoimmune, Experimental', 'Gastrointestinal Microbiome', 'Herpesvirus 3, Human', 'Humans', 'Multiple Sclerosis', ... | 30,341,184 | [['B01.050'], ['G04.146.954.035'], ['B03.510.024.100', 'B03.510.460.400.400.049.100'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.600.150.150.114'], ['A11'], ['A11.251'], ['C10.314'], ['E02.642.249'], ['G07.203.300.456', 'J02.500.456'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.114.703.300', 'C10.228... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
AdaBoost based multi-instance transfer learning for predicting proteome-wide interactions between Salmonella and human proteins. | Pathogen-host protein-protein interaction (PPI) plays an important role in revealing the underlying pathogenesis of viruses and bacteria. The need of rapidly mapping proteome-wide pathogen-host interactome opens avenues for and imposes burdens on computational modeling. For Salmonella typhimurium, only 62 interactions ... | ['Databases, Protein', 'Gene Ontology', 'Host-Pathogen Interactions', 'Humans', 'Protein Interaction Maps', 'Proteome', 'Salmonella Infections', 'Salmonella typhimurium'] | 25,330,226 | [['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['H01.158.273.343.249.099', 'H01.770.644.145.350.124', 'L01.224.050.375.480.500.500', 'L01.313.500.750.300.550.500.500', 'L01.453.245.945.079.500'], ['G06.462', 'G16.527.200'], ['B01.05... | ['Information Science [L]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Calcaneal Displacement Osteotomies - Less Soft Tissue Irritation in Lateral Compression Plate than Screws. | PURPOSE OF THE STUDY With the concept of the lateral compression plate (LLCP) a technique has been available designed to combine the advantages of a fixed-angle fixation with a complete sinking of the implant into the proximal bone. The objective of the present study was to investigate the results of the LLCP compared ... | ['Bone Plates', 'Bone Screws', 'Bony Callus', 'Calcaneus', 'Comparative Effectiveness Research', 'Female', 'Flatfoot', 'Fracture Fixation, Internal', 'Germany', 'Humans', 'Male', 'Middle Aged', 'Osteotomy', 'Outcome Assessment, Health Care', 'Postoperative Complications', 'Soft Tissue Injuries'] | 30,257,770 | [['E07.695.370.374', 'E07.858.442.660.460.374', 'E07.858.690.725.460.374'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['A10.165.265.200'], ['A02.835.232.043.300.710.300'], ['H01.770.644.145.360.500', 'N05.425.157'], ['C05.330.488.655.250', 'C05.330.495.681.250', 'C05.660.585.512.380.813... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Closing the Loop: Optimizing Diabetes Care in the Hospital by Addressing Dispersed Information in Electronic Health Records and Using Clinical Decision Support. | Multiple factors hinder the management of diabetes in hospitals. Amid the demands of practice, health care providers must collect, collate, and analyze multiple data points to optimally interpret glucose control and manage insulin dosing. Such data points are commonly dispersed in different sections of electronic healt... | ['Clinical Decision-Making', 'Decision Support Systems, Clinical', 'Diabetes Mellitus', 'Electronic Health Records', 'Hospitals', 'Humans'] | 30,526,010 | [['E01.055'], ['L01.313.500.750.300.190'], ['C18.452.394.750', 'C19.246'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.530.250', 'N06.850.520.308.940.968.625.250'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Optical Coherence Tomography Angiography in Foveal Hypoplasia. | BACKGROUND AND OBJECTIVE: A retrospective case series reporting optical coherence tomography angiography (OCTA) findings in foveal hypoplasia.PATIENTS AND METHODS: Patients with foveal hypoplasia who presented to the authors' tertiary eye center. Cases of foveal hypoplasia that underwent OCTA were reviewed, and the cli... | ['Adult', 'Child, Preschool', 'Eye Diseases, Hereditary', 'Female', 'Fluorescein Angiography', 'Fovea Centralis', 'Fundus Oculi', 'Humans', 'Male', 'Nystagmus, Congenital', 'Tomography, Optical Coherence', 'Visual Acuity', 'Young Adult'] | 27,977,835 | [['M01.060.116'], ['M01.060.406.448'], ['C11.270', 'C16.320.290'], ['E01.370.370.050.350', 'E01.370.380.250'], ['A09.371.729.522.436'], ['A09.371.729.313'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.292.562.675.300', 'C11.590.400.300', 'C16.614.643'], ['E01.370.350.589.249.500', 'E01.370.350.825.805.500', ... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Reduced expression of focal adhesion kinase in intrahepatic cholangiocarcinoma is associated with poor tumor differentiation. | OBJECTIVE: Focal adhesion kinase (FAK) expression has been linked to tumor cell invasion and metastasis, but its role in intrahepatic cholangiocarcinoma (ICC) has not been addressed. The goal of this study was to investigate FAK expression in ICC and to assess whether its expression is correlated with clinicopathologic... | ['Adult', 'Aged', 'Biomarkers, Tumor', 'Cell Differentiation', 'Cholangiocarcinoma', 'Disease-Free Survival', 'Female', 'Focal Adhesion Protein-Tyrosine Kinases', 'Humans', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Prognosis', 'Survival Rate'] | 17,687,194 | [['M01.060.116'], ['M01.060.116.100'], ['D23.101.140'], ['G04.152'], ['C04.557.470.200.025.450'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['D08.811.913.696.620.682.725.049', 'D12.644.360.287', 'D12.776.47... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Classification of type-II restriction endonucleases and cloning of non-identical cohesive-end fragments without self-polymerization using nonpalindromic oligodeoxyribonucleotide adapters. | Enzymatic partial filling-in of recessed 3'-end sequences, left after digestion of DNA by the restriction endonucleases (ENases) Sau3A and SalI, with the Klenow fragment of E. coli DNA polymerase I allows the forced ligation of the resulting fragments; this technology is already used for subcloning and for genomic bank... | ['Base Composition', 'Base Sequence', 'Cloning, Molecular', 'DNA, Recombinant', 'Deoxyribonucleases, Type II Site-Specific', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Polymorphism, Restriction Fragment Length', 'Transformation, Genetic'] | 1,676,386 | [['G02.111.080'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.220'], ['D13.444.308.460'], ['D08.811.150.280.260', 'D08.811.277.352.335.350.300.260', 'D08.811.277.352.355.325.300.260'], ['L01.453.245.667'], ['E05.393.420.601.575'], ['G05.365.795.595'], ['G05.728.865']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Biodistribution of rhodamine-123 in nude mice heterotransplanted with human squamous cell carcinomas. | Rhodamine-123 uptake and release was determined in nu/nu mice heterotransplanted with P3 human squamous carcinomas to assess its value as an in vivo laser photosensitizer for treatment of solid tumors. Following intraperitoneal injection of Rh-123 (1 micrograms/g of body weight), mice were killed at 2, 4, 6 and 24 hour... | ['Animals', 'Carcinoma, Squamous Cell', 'Fluorescent Dyes', 'Gastric Mucosa', 'Humans', 'Intestinal Mucosa', 'Kidney', 'Liver', 'Lung', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Middle Aged', 'Muscles', 'Neoplasm Transplantation', 'Rhodamine 123', 'Rhodamines', 'Skin', 'Spectrometry, Fluorescence', 'Spleen'... | 1,495,351 | [['B01.050'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['A03.556.875.875.440', 'A10.615.550.291'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.369', 'A10.615.550.444'], ['A05.810.453'], ['A03.620'], ['A04.411'], ['B01.050.150.900.649.313.992.635.... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Endovascular Treatment of Atherosclerotic Iliac Stenosis: Local and Systemic Complications of the Open Brachial Access. | BACKGROUND: The femoral access is the approach of reference for iliac angioplasty. In the current context of an early ambulation and a minimization of in-hospital stay period, the brachial access seems to be an appropriate approach, especially that long and small diameter equipments are available. Furthermore, it is ex... | ['Aged', 'Angioplasty', 'Arterial Occlusive Diseases', 'Brachial Artery', 'Constriction, Pathologic', 'Female', 'Hematoma', 'Humans', 'Iliac Artery', 'Kaplan-Meier Estimate', 'Length of Stay', 'Logistic Models', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Odds Ratio', 'Punctures', 'Retrospective Studies', 'Risk Fa... | 26,802,290 | [['M01.060.116.100'], ['E02.148.050', 'E04.100.814.529.124', 'E04.502.382.124', 'E05.157.016'], ['C14.907.137'], ['A07.015.114.139'], ['C23.300.287'], ['C23.550.414.838'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.444'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Substitution of care for chronic heart failure from the hospital to the general practice: patients' perspectives. | BACKGROUND: Shifting care from the secondary to the primary system may present an opportunity to ensure that the increasing number of patients with chronic heart failure (CHF) receive high-quality care while containing costs. However, shifting from secondary to primary care might seem radical to patients. A qualitative... | ['Attitude to Health', 'Clinical Competence', 'Cost Savings', 'Female', 'General Practice', 'Health Services Accessibility', 'Heart Failure', 'Hospitalization', 'Humans', 'Male', 'Middle Aged', 'Netherlands', 'Organizational Policy', 'Patient Preference', 'Policy Making', 'Primary Health Care', 'Qualitative Research', ... | 29,316,896 | [['F01.100.150', 'N05.300.150'], ['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['N03.219.151.160.200'], ['H02.403.340'], ['N04.590.374.350', 'N05.300.430'], ['C14.280.434'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.542.651'], ['I01.655.500.550'... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Prospective seroepidemiological study of role of human papillomavirus in non-cervical anogenital cancers. | OBJECTIVE: To evaluate the association between infection with the major oncogenic types of human papillomavirus and the risk of developing non-cervical anogenital cancers in a cohort followed up prospectively.DESIGN: Data from two large serum banks to which about 700,000 people had donated serum samples were followed u... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anus Neoplasms', 'Cohort Studies', 'Female', 'Finland', 'Humans', 'Male', 'Middle Aged', 'Norway', 'Odds Ratio', 'Papillomavirus Infections', 'Prospective Studies', 'Risk Factors', 'Seroepidemiologic Studies', 'Tumor Virus Infections', 'Urologic Neoplasms', 'Vaginal Neoplasms', '... | 9,310,566 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.274.476.411.307.790.040', 'C06.301.371.411.307.790.040', 'C06.405.249.411.307.790.040', 'C06.405.469.491.307.790.040', 'C06.405.469.860.101.163', 'C06.405.469.860.180.500.040'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Evaluation of the long-term variability of seawater salinity and temperature in response to natural and anthropogenic stressors in the Arabian Gulf. | Evaluating the long-term variability of the seawater salinity and temperature due to climate change is a limiting economical and operational factor in planning the design of new and expansion of existing desalination plants. This need is amplified in the Arabian Gulf due to the natural arid climate and anthropological ... | ['Climate Change', 'Ecosystem', 'Environmental Monitoring', 'Oceans and Seas', 'Salinity', 'Seawater', 'Stress, Physiological', 'Temperature'] | 24,055,462 | [['G16.500.175.374'], ['G16.500.275.157', 'N06.230.124'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.625', 'G16.500.275.725.500.650', 'Z01.756'], ['G02.640.500'], ['G16.500.275.725.500'], ['G07.775'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.71... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Antioxidative, protein kinase inhibition and antibacterial potential of seven mango varieties cultivated in Pakistan. | Peel, pulp and kernel extracts of seven mango fruit (varieties) were analyzedsubjected for antibacterial and antioxidative potential. Langra peel showed good activity against B. subtilis, S. aureus and E. aerogenes. Good zone of inhibition by chaunsa kernel (28mm) and pulp (22mm) against Streptomyces stipulate its pote... | ['Anti-Bacterial Agents', 'Antioxidants', 'Biphenyl Compounds', 'Drug Evaluation, Preclinical', 'Free Radical Scavengers', 'Fruit', 'Mangifera', 'Microbial Sensitivity Tests', 'Pakistan', 'Phenols', 'Picrates', 'Plant Extracts', 'Protein Kinase Inhibitors', 'Seeds', 'Species Specificity', 'Streptomyces'] | 31,608,891 | [['D27.505.954.122.085'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D02.455.426.559.389.185'], ['E05.290.750', 'E05.337.550'], ['D27.505.519.217.500'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['B01.650.940.800.575.912.250.044.416'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.5... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 |
Platelet 5-HT concentration and comorbid depression in war veterans with and without posttraumatic stress disorder. | BACKGROUND: The serotonergic system is implicated in the pathophysiology of posttraumatic stress disorder (PTSD) and depression. The present study focused on platelet serotonin (5-HT) concentration and symptoms of comorbid depression in war veterans with or without PTSD.METHODS: PTSD and depression were evaluated using... | ['Adult', 'Biomarkers', 'Blood Platelets', 'Case-Control Studies', 'Comorbidity', 'Depressive Disorder', 'Feeding and Eating Disorders', 'Humans', 'Male', 'Middle Aged', 'Serotonin', 'Severity of Illness Index', 'Stress Disorders, Post-Traumatic', 'Veterans', 'Warfare'] | 12,798,257 | [['M01.060.116'], ['D23.101'], ['A11.118.188', 'A15.145.229.188'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['N05.715.350.225', 'N06.850.490.687'], ['F03.600.300'], ['F03.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D02.092.211.215.801.852', 'D03.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Vaccination against hepatitis B in health workers and other staff in Barcelona]. | OBJECTIVE: To analyse the results of a hepatitis B vaccination programme, in order to find the levels of acceptance of the programme and adherence to it, as well as the immunological response and the impact of age, gender and the index of corporal mass (ICM).DESIGN: This was a retrospective study.SETTING: Primary Care.... | ['Adult', 'Age Factors', 'Body Mass Index', 'Female', 'Health Personnel', 'Hepatitis B', 'Hepatitis B Antibodies', 'Hepatitis B Vaccines', 'Humans', 'Male', 'Middle Aged', 'Occupational Health', 'Program Evaluation', 'Retrospective Studies', 'Sex Factors', 'Spain'] | 8,257,754 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.526.485', 'N02.360'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['D12.776.124.486.485.114.254.450.504', 'D12.776.124.7... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[The ultrasonic diagnosis of an early abnormal pregnancy]. | During the period of January 1993 to February 1994, 70 pregnant women had an ultrasonic diagnosis of abnormal pregnancy. 111 ultrasound examinations were made--mean 1.6 of each woman. The ultrasonic diagnosis up to 70 women was: missed abortion--35 women (50%), blighted ovum--30 women (42.9%), other diagnosis--5 women ... | ['Abortion, Missed', 'Female', 'Humans', 'Pregnancy', 'Pregnancy Complications', 'Pregnancy Trimester, First', 'Ultrasonography, Prenatal'] | 9,254,554 | [['C13.703.039.173'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['C13.703'], ['G08.686.707.408'], ['E01.370.350.850.865', 'E01.370.378.630.865']] | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immunological mechanisms of corticosteroid therapy in chronic active hepatitis: analysis of peripheral blood suppressor T-cell and interleukin 2 activities. | To investigate the immunological mechanisms underlying corticosteroid therapy in chronic active hepatitis (CAH), in vitro effects of prednisolone on suppressor T-cell and interleukin 2 (IL-2) activities were examined in six corticosteroid therapy-effective and six therapy-ineffective patients with CAH prior to the ther... | ['Female', 'Hepatitis, Chronic', 'Humans', 'Immune Tolerance', 'In Vitro Techniques', 'Interleukin-2', 'Lymphocyte Activation', 'Male', 'Prednisolone', 'T-Lymphocytes', 'T-Lymphocytes, Regulatory'] | 2,969,786 | [['C06.552.380.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.535.425'], ['E05.481'], ['D12.644.276.374.465.021', 'D12.644.276.374.480.372', 'D12.776.467.374.465.021', 'D12.776.467.374.480.372', 'D23.529.374.465.155', 'D23.529.374.480.372'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', '... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Using facial electromyography to detect preserved emotional processing in disorders of consciousness: A proof-of-principle study. | OBJECTIVE: To examine whether emotional functioning can be observed in patients who are behaviourally non-responsive using peripheral markers of emotional functioning.METHOD: We tested two patients, both diagnosed as being in a vegetative state (VS) following hypoxia secondary to cardiac arrest. Thirty-seven healthy pa... | ['Adolescent', 'Adult', 'Consciousness Disorders', 'Electromyography', 'Emotions', 'Facial Expression', 'Facial Muscles', 'Female', 'Humans', 'Male', 'Middle Aged', 'Persistent Vegetative State', 'Reaction Time', 'Wit and Humor as Topic', 'Young Adult'] | 27,469,527 | [['M01.060.057'], ['M01.060.116'], ['C10.597.606.358', 'C23.888.592.604.359', 'F01.700.315', 'F03.615.300'], ['E01.370.405.255', 'E01.370.530.255'], ['F01.470'], ['E01.370.600.225', 'F01.145.209.530.385'], ['A02.633.567.400', 'A14.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.228.14... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Humanities [K]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Developmental differences in antagonism of NMDA toxicity by the polyamine site antagonist ifenprodil. | Antagonists of 4 distinct regulatory sites on the N-methyl-D-aspartate (NMDA) receptor were tested for their ability to attenuate NMDA-mediated acute excitotoxicity in isolated chick retina of various embryonic ages between days 11 and 19 in ovo. Acute excitotoxicity was monitored by histology and by release of endogen... | ['Amino Acids', 'Animals', 'Biogenic Polyamines', 'Chick Embryo', 'Dizocilpine Maleate', 'Kynurenic Acid', 'N-Methylaspartate', 'Pipecolic Acids', 'Piperidines', 'Receptors, Glutamate', 'Receptors, Glycine', 'Receptors, N-Methyl-D-Aspartate', 'Receptors, Neurotransmitter', 'Receptors, Phencyclidine', 'Retina'] | 1,315,224 | [['D12.125'], ['B01.050'], ['D02.092.211.415'], ['A13.350.150', 'A16.331.200'], ['D02.455.426.559.847.181.384.380', 'D04.615.181.384.380'], ['D03.066.942.505', 'D03.633.100.810.350.400'], ['D12.125.067.500.400', 'D12.125.119.170.400'], ['D03.066.758', 'D03.383.621.758'], ['D03.383.621'], ['D12.776.543.750.720.200.450']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Right ventricle dimensions and function in response to acute hypoxia in healthy human subjects. | AIM: Acute hypoxia produces acute vasoconstriction in the pulmonary circulation with consequences on right ventricular (RV) structure and function. Previous investigations in healthy humans have been restricted to measurements after altitude acclimatization or were interrupted by normoxia. We hypothesized that immediat... | ['Adult', 'Echocardiography', 'Exercise', 'Female', 'Healthy Volunteers', 'Heart Ventricles', 'Humans', 'Hypoxia', 'Male'] | 27,332,955 | [['M01.060.116'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['G11.427.410.698.277', 'I03.350'], ['M01.774.500', 'M01.955.236'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.852.079']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Earthquakes and building design: a primer for the laboratory animal professional. | Earthquakes can occur in most regions of the United States, so it might be necessary to reinforce vulnerable animal facilities to better protect research animals during these unpredictable events. A risk analysis should include an evaluation of the seismic hazard risk at the proposed building site balanced against the ... | ['Animals', 'Animals, Laboratory', 'Building Codes', 'Costs and Cost Analysis', 'Earthquakes', 'Facility Design and Construction', 'Proportional Hazards Models', 'Safety', 'United States'] | 15,995,695 | [['B01.050'], ['B01.050.050.199'], ['N02.278.200.100'], ['N03.219.151'], ['G01.311.250', 'N06.230.100.230.200'], ['J01.086.339', 'N02.278.200'], ['E05.318.740.500.700', 'E05.318.740.600.700', 'E05.318.740.750.725', 'E05.318.740.998.825', 'E05.599.835.900', 'N05.715.360.750.530.650', 'N05.715.360.750.625.650', 'N05.715.... | ['Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Results From Australia's 2016 Report Card on Physical Activity for Children and Youth. | BACKGROUND: Two years on from the inaugural Active Healthy Kids Australia (AHKA) Physical Activity Report Card, there has been little to no change with the majority of Australian children still insufficiently active.METHODS: The 2016 AHKA Report Card was developed using the best available national- and state-based phys... | ['Adolescent', 'Australia', 'Child', 'Exercise', 'Female', 'Health Behavior', 'Health Promotion', 'Health Surveys', 'Humans', 'Male', 'Motor Activity', 'Play and Playthings', 'Program Evaluation', 'Sedentary Behavior', 'Sports'] | 27,848,737 | [['M01.060.057'], ['Z01.639.100', 'Z01.678.100.373'], ['M01.060.406'], ['G11.427.410.698.277', 'I03.350'], ['F01.145.488'], ['I02.233.332.445', 'N02.421.726.407.579'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.632', 'G11.427... | ['Named Groups [M]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Reverse left ventricular remodeling by intermittent dobutamine infusions and amiodarone in end-stage heart failure due to idiopathic dilated cardiomyopathy. | BACKGROUND: The aim of this study was to evaluate the long-term effect of combined intermittent dobutamine infusions (IDI) and oral amiodarone on reverse left ventricular (LV) remodeling and hemodynamics of patients with idiopathic dilated cardiomyopathy (IDC) and end-stage congestive heart failure (CHF).METHODS: This ... | ['Administration, Oral', 'Adult', 'Aged', 'Amiodarone', 'Cardiomyopathy, Dilated', 'Cardiovascular Agents', 'Dobutamine', 'Female', 'Heart Failure', 'Hemodynamics', 'Humans', 'Infusions, Intravenous', 'Male', 'Middle Aged', 'Prospective Studies', 'Stroke Volume', 'Ventricular Remodeling'] | 16,183,152 | [['E02.319.267.100'], ['M01.060.116'], ['M01.060.116.100'], ['D03.633.100.127.075'], ['C14.280.195.160', 'C14.280.238.070', 'C16.320.488.750'], ['D27.505.954.411'], ['D02.092.311.220', 'D02.092.471.683.410', 'D02.455.426.559.389.657.166.175.220'], ['C14.280.434'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Endoscopic Sclerotherapy with a Large Volume of High Concentration of Cyanoacrylate for Jejunal Variceal Bleeding bys Single-Balloon Enteroscopy. | Jejunal varices are a rare manifestation of portal hypertension, and they are associated with a high mortality and poor prognosis when bleeding occurs. A bleeding jejunal varix is much more challenging to diagnose and manage because of its anatomic location. Herein, we describe the case of a 62-year-old man with active... | ['Carcinoma, Hepatocellular', 'Cyanoacrylates', 'Endoscopy', 'Esophageal and Gastric Varices', 'Fatal Outcome', 'Gastrointestinal Hemorrhage', 'Humans', 'Hypertension, Portal', 'Jejunum', 'Liver Cirrhosis', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Sclerotherapy', 'Single-Balloon Enteroscopy', 'Varicose Veins'] | 30,344,299 | [['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['D02.241.081.069.366', 'D02.626.290', 'D05.750.259', 'D25.720.259', 'D25.919.367', 'J01.637.051.720.259', 'J01.637.051.919.367'], ['E01.370.388.250', 'E04.502.250'], ['C06.405.117.240', 'C06.552.494.414'], ['E05.318.308.985.550.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Epithelial overexpression of BDNF or NT4 disrupts targeting of taste neurons that innervate the anterior tongue. | Brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT4) are essential for the survival of geniculate ganglion neurons, which provide the sensory afferents for taste buds of the anterior tongue and palate. To determine how these target-derived growth factors regulate gustatory development, the taste system was... | ['Animals', 'Animals, Newborn', 'Body Patterning', 'Brain-Derived Neurotrophic Factor', 'Cell Survival', 'Embryonic and Fetal Development', 'Epithelium', 'Gene Expression Regulation, Developmental', 'Mice', 'Mice, Transgenic', 'Nerve Growth Factors', 'Neurons', 'Taste Buds', 'Tongue'] | 11,401,409 | [['B01.050'], ['B01.050.050.282'], ['G07.345.500.100'], ['D12.644.276.860.100', 'D12.776.467.860.100', 'D12.776.631.600.100', 'D23.529.850.100'], ['G04.346'], ['G07.345.500.325', 'G08.686.784.170'], ['A10.272'], ['G05.308.310'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.3... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oxygen and substrate deprivation on isolated rat cardiac myocytes: temporal relationship between electromechanical and biochemical consequences. | The effects of hypoxia and reoxygenation on action potentials (AP), contractions, and certain biochemical parameters were studied in isolated rat ventricular myocytes in monolayer culture in the presence and absence of glucose. Substrate deprivation alone had no influence on the basal properties. In the presence of glu... | ['Action Potentials', 'Adenosine Triphosphate', 'Animals', 'Cells, Cultured', 'Electrophysiology', 'Glucose', 'Hypoxia', 'L-Lactate Dehydrogenase', 'Lactates', 'Membrane Potentials', 'Myocardial Contraction', 'Myocardium', 'Rats', 'Rats, Inbred Strains', 'Time Factors'] | 2,390,741 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['A11.251'], ['H01.158.344.528', 'H01.158.782.236'], ['D09.947.875.359.448'], ['C23.888.852.079'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['D02.241.511.459... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Interaction with caveolin-1 modulates vascular ATP-sensitive potassium (KATP) channel activity. | ATP-sensitive potassium channels (K(ATP) channels) of arterial smooth muscle are important regulators of arterial tone, and hence blood flow, in response to vasoactive transmitters. Recent biochemical and electron microscopic evidence suggests that these channels localise to small vesicular invaginations of the plasma ... | ['Amino Acid Sequence', 'Animals', 'Aorta, Thoracic', 'Caveolin 1', 'HEK293 Cells', 'Humans', 'KATP Channels', 'Male', 'Molecular Sequence Data', 'Muscle, Smooth, Vascular', 'Potassium Channels, Inwardly Rectifying', 'Protein Binding', 'Protein Structure, Tertiary', 'Rats', 'Rats, Wistar', 'Sensitivity and Specificity'... | 20,624,795 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A07.015.114.056.372'], ['D12.644.360.024.264', 'D12.776.157.057.010', 'D12.776.476.024.280', 'D12.776.543.990.100.500', 'D12.776.744.287'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.157.530.400.600.450.5... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
An epidemiological comparison of Mexican-American and white non-Hispanic 8th- and 12th-grade students' substance use. | Surveys of drug and alcohol use were conducted with a national probability sample of 8th- and 12th-grade Mexican-American and White non-Hispanic youth. The drug and alcohol epidemiology is representative of US Mexican-American youth residing in communities with populations of 2500 or more, at least 10% of whom are Mexi... | ['Adolescent', 'Child', 'European Continental Ancestry Group', 'Female', 'Health Behavior', 'Health Surveys', 'Humans', 'Male', 'Mexican Americans', 'Prevalence', 'Substance-Related Disorders', 'Surveys and Questionnaires', 'United States'] | 1,536,366 | [['M01.060.057'], ['M01.060.406'], ['M01.686.508.400'], ['F01.145.488'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.754.441.500'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
When information sharing is not enough. | This paper explores information sharing in multidisciplinary clinical collaboration between three hospitals. Our study draws on qualitative interviews with surgeons and radiologists in two county hospitals and one university hospital. The analysis shows that the actors shared a restricted amount of information about th... | ['Academic Medical Centers', 'Access to Information', 'Aged', 'Aortic Aneurysm', 'Communication', 'Cooperative Behavior', 'Electronic Health Records', 'Hospital Information Systems', 'Hospitals', 'Humans', 'Medical Informatics', 'Norway', 'Radiography', 'Risk', 'Systems Integration'] | 21,893,773 | [['N02.278.020'], ['I01.880.604.473.352.500.030', 'L01.143.024', 'L01.737.030'], ['M01.060.116.100'], ['C14.907.055.239', 'C14.907.109.139'], ['F01.145.209', 'L01.143'], ['F01.145.813.115'], ['E05.318.308.940.968.625.500', 'N04.452.859.564.650.125', 'N05.715.360.300.715.500.530.250', 'N06.850.520.308.940.968.625.250'],... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]',... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Upregulated galectin-3 is not a critical disease mediator of cardiomyopathy induced by â2 | Preclinical studies have demonstrated that anti-galectin-3 (Gal-3) interventions are effective in attenuating cardiac remodeling, fibrosis, and dysfunction. We determined, in a transgenic (TG) mouse model of fibrotic cardiomyopathy, whether Gal-3 expression was elevated and whether Gal-3 played a critical role in disea... | ['Amino Sugars', 'Animals', 'Cardiomyopathies', 'Disease Models, Animal', 'Fibrosis', 'Galectin 3', 'Genetic Predisposition to Disease', 'Humans', 'Male', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Myocytes, Cardiac', 'Pectins', 'Phenotype', 'Receptors, Adrenergic, beta-2', 'Severity of Illness Index', 'Up-Regulation', '... | 29,424,570 | [['D09.067'], ['B01.050'], ['C14.280.238'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.550.355'], ['D12.776.503.307.300'], ['C23.550.291.687.500', 'G05.380.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Kinetics of advanced glycation end products formation on bovine serum albumin with various reducing sugars and dicarbonyl compounds in equimolar ratios. | Reducing sugars and reactive dicarbonyl compounds play a major role in glycation of proteins in vivo. Glycation of proteins is the first step in of a nonenzymatic reaction, resulting in advanced glycation end products (AGEs). AGEs can inactivate proteins or modify their biological activities. Therefore, it is important... | ['Absorption', 'Animals', 'Arginine', 'Carbohydrates', 'Cattle', 'Fructose', 'Glucose', 'Glycation End Products, Advanced', 'Humans', 'Kinetics', 'Molecular Weight', 'Neurodegenerative Diseases', 'Ribose', 'Serum Albumin, Bovine', 'Silver Staining', 'Spectrometry, Fluorescence', 'Time Factors'] | 22,533,432 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['B01.050'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D09'], ['B01.050.150.900.649.313.500.380.271'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['D09.947.875.359.448'], ['D12.776.643.500'], ['B01.050.150.900.649.313.988.400.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Infected tibia defect fractures treated with the Masquelet technique. | The treatment after open and infected fractures with extensive soft tissue damage and bone deficit remains a challenging clinical problem. The technique described by Masquelet, using a temporary cement spacer to induce a membrane combined with reconstructive soft tissue coverage, is a possible solution. This study desc... | ['Adult', 'Aged', 'Autografts', 'Bone Transplantation', 'Debridement', 'Female', 'Follow-Up Studies', 'Fracture Fixation, Internal', 'Fracture Healing', 'Fractures, Open', 'Humans', 'Internal Fixators', 'Male', 'Middle Aged', 'Osteomyelitis', 'Reoperation', 'Retrospective Studies', 'Tibial Fractures'] | 28,514,314 | [['M01.060.116'], ['M01.060.116.100'], ['A01.941.750'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['E04.176'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.555.300.300'], ['G16.762.891.500'], ['C26.404.311'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of the Casein-Derived Peptide Met-Lys-Pro on Cognitive Function in Community-Dwelling Adults Without Dementia: A Randomized, Double-Blind, Placebo-Controlled Trial. | Background: Preventative measures have recently been taken to reduce the incidence of Alzheimer's disease worldwide. We previously showed that Met-Lys-Pro (MKP), a casein-derived angiotensin-converting enzyme inhibitory peptide with the potential to cross the blood-brain barrier, attenuated cognitive decline in a mouse... | ['Administration, Oral', 'Aged', 'Caseins', 'Cognition', 'Cognitive Dysfunction', 'Double-Blind Method', 'Female', 'Humans', 'Independent Living', 'Male', 'Neuropsychological Tests', 'Nootropic Agents', 'Oligopeptides', 'Tablets', 'Treatment Outcome'] | 32,546,992 | [['E02.319.267.100'], ['M01.060.116.100'], ['D12.776.256.159.750.207', 'D12.776.744.150'], ['F02.463.188'], ['F03.615.250.700'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I03.050.500', 'N01.224.791.550', 'N06.850.505.400.800.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
A case of intestinal MALToma with co-existent tuberculosis and Peutz-Jeghers polyp. | A 22-year-old male patient underwent a segmental resection of the ileum due to clinical symptoms of bowel obstruction and radiological evidence of ileal wall thickening and enlarged mesenteric nodes. Histopathological examination of the resected specimen revealed an extranodal marginal zone B-cell lymphoma(MALToma) of ... | ['Humans', 'Ileal Neoplasms', 'Intestinal Obstruction', 'Intestinal Polyps', 'Laparotomy', 'Lymphoma, B-Cell, Marginal Zone', 'Male', 'Peutz-Jeghers Syndrome', 'Treatment Outcome', 'Tuberculosis', 'Young Adult'] | 25,766,352 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.476.411.501', 'C06.301.371.411.501', 'C06.405.249.411.501', 'C06.405.469.420.501', 'C06.405.469.491.501'], ['C06.405.469.531'], ['C23.300.825.411'], ['E04.406'], ['C04.557.386.480.150.570', 'C15.604.515.569.480.150.570', 'C20.683.515.761.480.150.570'], ['C... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Thermal sensation and pain in oral lichen planus and lichenoid reaction. | BACKGROUND: Our previous findings in oral lichen planus (OLP) and lichenoid reactions (LR) raised the question whether the histopathological changes observed in sensory and autonomic innervation produce oral sensory disorders.METHODS: Spontaneous pain was assessed using the Visual Analogue Scale (VAS). Thermal pain thr... | ['Analysis of Variance', 'Candidiasis, Oral', 'Case-Control Studies', 'Facial Pain', 'Female', 'Humans', 'Lichen Planus, Oral', 'Male', 'Middle Aged', 'Mouth Mucosa', 'Pain Measurement', 'Pain Threshold', 'Pressure', 'Statistics, Nonparametric', 'Thermosensing'] | 12,558,957 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C01.150.703.160.180', 'C07.465.130'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.888.592.612.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.465.397', 'C17.800.859.475.560.397'], ['M01.060.116.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis of the 2Fe subcluster of the [FeFe]-hydrogenase H cluster on the HydF scaffold. | The organometallic H cluster at the active site of [FeFe]-hydrogenase consists of a 2Fe subcluster coordinated by cyanide, carbon monoxide, and a nonprotein dithiolate bridged to a [4Fe-4S] cluster via a cysteinate ligand. Biosynthesis of this cluster requires three accessory proteins, two of which (HydE and HydG) are ... | ['Clostridium', 'Electron Spin Resonance Spectroscopy', 'GTP Phosphohydrolases', 'Guanosine Triphosphate', 'Hydrogenase', 'Iron', 'Iron-Sulfur Proteins', 'Models, Molecular', 'Protein Binding', 'Protein Structure, Tertiary', 'Spectroscopy, Fourier Transform Infrared', 'Sulfur'] | 20,498,089 | [['B03.300.390.400.200', 'B03.353.625.375.500', 'B03.510.415.400.200'], ['E05.196.867.519.274'], ['D08.811.277.040.330'], ['D03.633.100.759.646.454.504', 'D13.695.667.454.504', 'D13.695.827.426.504'], ['D08.811.682.400'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D12.776.157.427.374.375', 'D12.776.55... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The Niemann-Pick C1 like 1 (NPC1L1) inhibitor ezetimibe improves metabolic disease via decreased liver X receptor (LXR) activity in liver of obese male mice. | Dyslipidemic patients with diabetes mellitus, including metabolic syndrome, are at increased risk of coronary heart disease. It has been reported that ezetimibe, a cholesterol absorption inhibitor, improves metabolic diseases in mice and humans. However, the underlying mechanism has been unclear. Here we explored the e... | ['Animals', 'Anticholesteremic Agents', 'Azetidines', 'Cells, Cultured', 'Diet, High-Fat', 'Ezetimibe', 'Fatty Liver', 'Glucose Metabolism Disorders', 'Hepatocytes', 'Intestinal Mucosa', 'Intestines', 'Lipid Metabolism', 'Liver X Receptors', 'Male', 'Membrane Transport Proteins', 'Mice', 'Mice, Obese', 'Orphan Nuclear ... | 24,773,344 | [['B01.050'], ['D27.505.519.186.071.202', 'D27.505.954.557.500.202'], ['D03.383.082.301'], ['A11.251'], ['G07.203.650.240.267'], ['D03.383.082.301.550'], ['C06.552.241'], ['C18.452.394'], ['A11.436.348'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124'], ['G03.458'], ['D12.776.260.531', 'D12.776.826.194'], ['D12... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Zinc enhances the cellular energy supply to improve cell motility and restore impaired energetic metabolism in a toxic environment induced by OTA. | Exogenous nutrient elements modulate the energetic metabolism responses that are prerequisites for cellular homeostasis and metabolic physiology. Although zinc is important in oxidative stress and cytoprotection processes, its role in the regulation of energetic metabolism remains largely unknown. In this study, we fou... | ['Blotting, Western', 'Cell Movement', 'Cell Survival', 'Energy Metabolism', 'HEK293 Cells', 'Humans', 'Ochratoxins', 'Superoxide Dismutase', 'Zinc'] | 29,116,164 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G04.198', 'G07.568.500.180'], ['G04.346'], ['G03.295'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.663.283.446.800.500', 'D03.633.100.150.446.800.500', 'D23.946... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Methodologic considerations in measuring glycosylated hemoglobin in epidemiologic studies. | Multiple linear regression was used to predict an incubated glycosylated hemoglobin value from the unincubated value and blood glucose. Hemoglobin A1 (HbA1) was measured by a disposable microcolumn technique in a large, geographically defined population of diabetic persons in southern Wisconsin. During the study, incub... | ['Age Factors', 'Blood Glucose', 'Diabetic Retinopathy', 'Glycated Hemoglobin A', 'Humans', 'Regression Analysis'] | 3,397,760 | [['N05.715.350.075', 'N06.850.490.250'], ['D09.947.875.359.448.500'], ['C11.768.257', 'C14.907.320.382', 'C19.246.099.500.382'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.750', 'N05.715.360.750.695', '... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Acute renal failure in falciparum malaria. | We report two patients who had cerebral malaria, heavy parasitemia, hyperbilirubinemia, hypercatabolism with rapid rises of blood urea and serum creatinine and acute renal failure. There was no evidence of intravascular hemolysis. Renal biopsy was consistent with acute tubular necrosis. Both patients responded to treat... | ['Acute Kidney Injury', 'Adult', 'Humans', 'Kidney', 'Kidney Tubular Necrosis, Acute', 'Malaria, Falciparum', 'Male', 'Parasitemia', 'Peritoneal Dialysis', 'Quinine', 'Renal Dialysis'] | 7,674,979 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['C12.777.419.780.050.500', 'C13.351.968.419.780.050.500'], ['C01.610.752.530.650', 'C01.920.875.650'], ['C01.610.695', 'C23.550.470.790.500.580'], ['E02.870.300.650', 'E02.912.800.650... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A quantitative assay for the juvenile hormones and their precursors using fluorescent tags. | BACKGROUND: The juvenile hormones (JHs) are sesquiterpenoid compounds that play a central role in insect reproduction, development and behavior. The lipophilic nature of JHs and their precursors, in conjunction with their low concentration in tissues and susceptibility to degradation had made their quantification diffi... | ['Aedes', 'Animals', 'Chromatography, High Pressure Liquid', 'Chromatography, Reverse-Phase', 'Clinical Chemistry Tests', 'Drosophila melanogaster', 'Fatty Acids, Monounsaturated', 'Fatty Acids, Unsaturated', 'Female', 'Fluorescent Dyes', 'Limit of Detection', 'Oxadiazoles', 'Sesquiterpenes', 'Spectrometry, Fluorescenc... | 22,928,033 | [['B01.050.500.131.617.720.500.500.750.712.500.875.100'], ['B01.050'], ['E05.196.181.400.300'], ['E05.196.181.400.495'], ['E01.370.225.124', 'E05.200.124'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['D10.251.355.325'], ['D10.251.355'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['E05.318.740.872.374', ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Tranexamic Acid Dosing for Cardiac Surgical Patients With Chronic Renal Dysfunction: A New Dosing Regimen. | BACKGROUND: Tranexamic acid (TXA) is a common antifibrinolytic agent used to minimize bleeding in cardiac surgery. Up to 50% cardiac surgical patients have chronic renal dysfunction (CRD). Optimal dosing of TXA in CRD remains poorly investigated. This is important as TXA is renally eliminated with accumulation in CRD. ... | ['Aged', 'Antifibrinolytic Agents', 'Cardiac Surgical Procedures', 'Cardiopulmonary Bypass', 'Drug Administration Schedule', 'Female', 'Hospital Mortality', 'Humans', 'Ischemia', 'Length of Stay', 'Male', 'Middle Aged', 'Postoperative Period', 'Prospective Studies', 'Quality of Health Care', 'Renal Insufficiency, Chron... | 29,309,319 | [['M01.060.116.100'], ['D27.505.519.421.500', 'D27.505.954.502.270.463.091'], ['E04.100.376', 'E04.928.220'], ['E04.292.413'], ['E02.319.283'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400', 'N06.850.520.308.985.550.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.513... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Detection of HIV-1 by polymerase chain reaction and culture in seronegative intravenous drug users in an inner-city emergency department. | STUDY BACKGROUND: After a health care worker's unprotected exposure to a patient's blood, the current recommendation is to obtain consent from the source for serologic testing for HIV. If the test is negative, no further follow-up of the exposed provider is usually indicated.OBJECTIVE: To determine if patients testing ... | ['Adult', 'Baltimore', 'Cross-Sectional Studies', 'DNA, Viral', 'Emergency Service, Hospital', 'Female', 'HIV Antibodies', 'HIV Seropositivity', 'HIV-1', 'Humans', 'Male', 'Polymerase Chain Reaction', 'Sensitivity and Specificity', 'Substance Abuse, Intravenous', 'Urban Population'] | 8,470,831 | [['M01.060.116'], ['Z01.107.567.875.500.500.100', 'Z01.433.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['D13.444.308.568'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['D12.776.124.486.485.114.254.150.440', 'D12.776.124.790.651.114.254.150.440', ... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A magnesium-induced RNA conformational switch at the internal ribosome entry site of hepatitis C virus genome visualized by atomic force microscopy. | The 5' untranslated region of hepatitis C virus (HCV) genomic RNA contains an internal ribosome entry site (IRES) element, composed of domains II-IV, which is required for cap-independent translation initiation. Little information on the 3D structure of the whole functional HCV IRES is still available. Here, we use ato... | ["5' Untranslated Regions", 'Genome, Viral', 'Hepacivirus', 'Magnesium', 'Microscopy, Atomic Force', 'Nucleic Acid Conformation', 'RNA Folding', 'RNA, Viral', 'Ribosomes'] | 25,510,496 | [['D13.444.735.544.875.885', 'D13.444.735.790.878.885', 'G05.360.340.024.220.880.885', 'G05.360.340.024.340.137.910.885'], ['G05.360.340.358.840'], ['B04.450.380', 'B04.820.578.344.475'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['G02.111.570.820.486', '... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Traumatic rupture of the aortic valve. Echocardiographic aspects. Apropos of a case]. | The appearance of a diastolic murmur in a pyrexial patient 15 days after trauma was suggestive of infectious endocarditis. This diagnosis was excluded, especially by echocardiography, and the aortic incompetence was attributed to the trauma. The value of echocardiography and the features of other reported cases are dis... | ['Accidents, Traffic', 'Adult', 'Aortic Valve', 'Aortic Valve Insufficiency', 'Echocardiography', 'Gentamicins', 'Humans', 'Male', 'Oxacillin', 'Pleural Effusion', 'Rupture', 'Staphylococcal Infections', 'Staphylococcus'] | 121,533 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lateral migration of a two-dimensional vesicle in unbounded Poiseuille flow. | The migration of a suspended vesicle in an unbounded Poiseuille flow is investigated numerically in the low Reynolds number limit. We consider the situation without viscosity contrast between the interior of the vesicle and the exterior. Using the boundary integral method we solve the corresponding hydrodynamic flow eq... | ['Computer Simulation', 'Lipid Bilayers', 'Membrane Fluidity', 'Microfluidics', 'Models, Chemical', 'Molecular Conformation', 'Motion', 'Unilamellar Liposomes'] | 18,352,047 | [['L01.224.160'], ['D10.570.510', 'J01.637.087.500.510'], ['G01.154.500', 'G02.111.550', 'G04.570'], ['E05.830.666', 'H01.671.808.500', 'J01.897.520.500.500'], ['E05.599.495'], ['G02.111.570.820'], ['G01.482'], ['D25.479.517.500', 'J01.637.051.479.517.500', 'J01.637.087.500.517.500']] | ['Information Science [L]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Clinical management of small (6- to 9-mm) polyps detected at screening CT colonography: a cost-effectiveness analysis. | OBJECTIVE: The primary aim of this model analysis was to compare the clinical and economic impacts of immediate polypectomy versus 3-year CT colonography (CTC) surveillance for small (6- to 9-mm) polyps detected at CTC screening.MATERIALS AND METHODS: A decision analysis model was constructed incorporating the expected... | ['Aged', 'Aged, 80 and over', 'Colonography, Computed Tomographic', 'Colorectal Neoplasms', 'Cost-Benefit Analysis', 'Female', 'Health Care Costs', 'Humans', 'Incidence', 'Intestinal Polyps', 'Male', 'Mass Screening', 'Middle Aged', 'Retrospective Studies', 'Survival Analysis', 'Survival Rate', 'United States'] | 18,941,093 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350.350.810.180', 'E01.370.350.600.350.700.810.180', 'E01.370.350.700.700.810.180', 'E01.370.350.700.810.810.180', 'E01.370.372.230'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Augmentation of rat brain endogenous monoamine oxidase inhibitory activity (tribulin) by electroconvulsive shock. | The effects of acute and subacute supramaximal and submaximal electroshock-induced convulsions on rat brain tribulin activity were investigated. Both supramaximal and submaximal shocks induced a marked increase, as measured 30 min after the onset of convulsions, with a significantly greater effect from the former. The ... | ['Animals', 'Brain', 'Electroshock', 'Isatin', 'Kinetics', 'Male', 'Monoamine Oxidase Inhibitors', 'Rats', 'Rats, Inbred Strains', 'Reference Values', 'Seizures'] | 1,857,560 | [['B01.050'], ['A08.186.211'], ['E05.723.402.403', 'F04.669.224'], ['D03.633.100.473.525'], ['G01.374.661', 'G02.111.490'], ['D27.505.519.389.616'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['E05.978.810'], ['C10.597.742', 'C23.888.592.742'... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interferon-ã expression in trophoblast cells in pregnant ewes challenged with Chlamydophila abortus. | Pregnant ewes were challenged with Chlamydia abortus at 91-98 days of gestation and euthanised at 14, 21 and 28 days post-challenge. IFNã mRNA labelling appeared to be co-localised with Chlamydial lipopolysaccharide within trophoblast cells in discrete areas lining the primary villi in the limbus and hilar zone of the ... | ['Abortion, Septic', 'Animals', 'Chlamydophila', 'Chlamydophila Infections', 'Female', 'Interferon-gamma', 'Pregnancy', 'RNA, Messenger', 'Sheep', 'Sheep Diseases', 'Trophoblasts'] | 21,722,966 | [['C01.674.173', 'C13.703.039.256', 'C13.703.700.173'], ['B01.050'], ['B03.440.190.190.230'], ['C01.150.252.400.210.250'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12.776.467.374.480.615.350', 'D23.529.374.440.893', 'D23.529.374.480.615.350'], ['G08.686.784.769'], ['D13.44... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Influence of volume and activation mode on polymerization shrinkage forces of resin cements. | The concern with the polymerization shrinkage of restorative resin composites also applies to resin cements. The aim of this study was to evaluate the influence of volume and polymerization mode on forces generated during polymerization shrinkage (FGPS) of resin cements. Two light-cured resin cements--Variolink II (VL;... | ['Dental Bonding', 'Polymerization', 'Resin Cements'] | 24,173,249 | [['E06.095'], ['G02.750'], ['D05.750.716.822.730', 'D25.339.291.750', 'D25.720.716.822.730', 'J01.637.051.339.291.750', 'J01.637.051.720.716.822.730']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The activity of membrane enzymes in homogenate fractions of rat kidney after administration of lead. | Rats received one or two consecutive daily ip injections, each 0.5 mg Pb2+/100 g body weight, and the kidneys were studied 48 or 24 hr, respectively, after the injection. Renal brush border preparations from Pb2+-treated rats exhibited significant decreases in the activity of alanine aminopeptidase and gamma-glutamyl t... | ['Alkaline Phosphatase', 'Aminopeptidases', 'Animals', 'CD13 Antigens', 'Kidney', 'Lead', 'Male', 'Microvilli', 'Rats', 'Rats, Inbred Strains', 'Sodium-Potassium-Exchanging ATPase', 'gamma-Glutamyltransferase'] | 6,132,470 | [['D08.811.277.352.650.035'], ['D08.811.277.656.350.100'], ['B01.050'], ['D08.811.277.656.350.100.160', 'D08.811.277.656.350.555.100', 'D08.811.277.656.675.555.100', 'D23.050.301.264.894.113', 'D23.101.100.894.113'], ['A05.810.453'], ['D01.268.556.435', 'D01.552.544.435'], ['A11.284.180.565'], ['B01.050.150.900.649.313... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A comprehensive register for diabetic outpatients: experience with desktop computing from 1987-1996. | Diabetes mellitus affects all parts of the body, and all aspects of life for the patient. To manage patients effectively, we need a record of who has diabetes, where they are treated, by whom, and with what results. In 1985 we devised a standardised data collection form in our clinic and in 1987 we established a compre... | ['Diabetes Mellitus', 'Humans', 'Medical Records Systems, Computerized', 'Outpatients', 'Registries'] | 9,700,434 | [['C18.452.394.750', 'C19.246'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.940.968.625', 'L01.313.500.750.300.695', 'N04.452.859.564.650', 'N05.715.360.300.715.500.530', 'N06.850.520.308.940.968.625'], ['M01.643.630'], ['E05.318.308.970', 'N04.452.859.819', 'N05.715.360.300.715.700', 'N06.850.520.3... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Is it safe to treat hyperthyroid patients with I-131 without fear of thyroid storm? | OBJECTIVES: Thyroid storm is extremely rare. However, hyperthyroid patients with severe thyrotoxicosis are frequently not treated immediately with I-131 for fear of thyroid storm but are placed on thiouracil drugs for varying periods of time. We demonstrate herein that it is safe to treat these patients with 1-131, wit... | ['Adolescent', 'Adrenergic beta-Antagonists', 'Adult', 'Causality', 'Comorbidity', 'Female', 'Humans', 'Hyperthyroidism', 'Incidence', 'Iodine Radioisotopes', 'Male', 'Middle Aged', 'Radiopharmaceuticals', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors', 'Texas', 'Thyroid Crisis', 'Treatment Outcome'] | 16,922,465 | [['M01.060.057'], ['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116'], ['N05.715.350.200', 'N06.850.490.625'], ['N05.715.350.225', 'N06.850.490.687'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C19.874.397'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Enhanced immunogenicity of Plasmodium falciparum peptide vaccines using a topical adjuvant containing a potent synthetic Toll-like receptor 7 agonist, imiquimod. | Plasmodium sporozoites injected into the skin by malaria-infected mosquitoes can be effectively targeted by antibodies that block parasite invasion of host hepatocytes and thus prevent the subsequent development of blood stage infections responsible for clinical disease. Malaria subunit vaccines require potent adjuvant... | ['Adjuvants, Immunologic', 'Administration, Topical', 'Aminoquinolines', 'Animals', 'Antibodies, Protozoan', 'Antibody Specificity', 'Female', 'Imiquimod', 'Immunoglobulin G', 'Injections, Subcutaneous', 'Malaria Vaccines', 'Mice', 'Mice, Inbred C57BL', 'Plasmodium falciparum', 'Protozoan Proteins', 'Toll-Like Receptor... | 19,047,411 | [['D27.505.696.477.067'], ['E02.319.267.120'], ['D03.633.100.810.050'], ['B01.050'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['G12.100'], ['D03.633.100.810.050.545'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.61... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adaptive genetic diversity and evidence of population genetic structure in the endangered Sierra Madre Sparrow (Xenospiza baileyi). | The magnitude and distribution of genetic diversity through space and time can provide useful information relating to evolutionary potential and conservation status in threatened species. In assessing genetic diversity in species that are of conservation concern, several studies have focused on the use of Toll-like rec... | ['Animals', 'Biological Evolution', 'Conservation of Natural Resources', 'Ecosystem', 'Endangered Species', 'Genetics, Population', 'Microsatellite Repeats', 'Phylogeny', 'Polymorphism, Genetic', 'Sparrows'] | 32,352,998 | [['B01.050'], ['G05.045', 'G16.075'], ['J01.256', 'N06.230.080'], ['G16.500.275.157', 'N06.230.124'], ['B01.050.050.565', 'G16.500.275.157.049.250', 'N06.230.080.200', 'N06.230.124.049.250'], ['H01.158.273.343.335'], ['G02.111.570.080.708.800.500', 'G05.360.080.708.800.500', 'G05.360.340.024.850.500'], ['G05.697', 'G16... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Advances in endosurgery. Treatment of ureteral-enteric anastomotic strictures. | The described endourologic technique of incision and dilation of a ureteral-intestinal stricture is effective in most patients. Indeed, with the outlined treatment regimen, less than 30 per cent of patients with ureteral-intestinal anastomotic strictures will eventually require open surgical revision. Further advances ... | ['Dilatation', 'Endoscopy', 'Fluoroscopy', 'Humans', 'Ileum', 'Ureteral Obstruction', 'Urinary Catheterization', 'Urinary Diversion'] | 3,407,031 | [['E05.284'], ['E01.370.388.250', 'E04.502.250'], ['E01.370.350.700.225'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124.684.249', 'A03.556.249.124'], ['C12.777.725.776', 'C13.351.968.725.776'], ['E01.370.390.820', 'E02.148.947', 'E05.157.500'], ['E04.950.774.852']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Revision surgery after primary spine fusion for idiopathic scoliosis. | STUDY DESIGN: Retrospective case series.OBJECTIVE: The objective of this study was to review the overall prevalence of, and indications for, reoperations after the index spine fusion for idiopathic scoliosis at our center.SUMMARY OF BACKGROUND DATA: Spine fusions for idiopathic scoliosis are expected to be the final th... | ['Adolescent', 'Child', 'Female', 'Humans', 'Male', 'Postoperative Complications', 'Reoperation', 'Retrospective Studies', 'Scoliosis', 'Spinal Fusion', 'Young Adult'] | 19,752,705 | [['M01.060.057'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.767'], ['E04.690'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500', 'N06.850.520.450.500.750.825'], ['C05.116.900.800.875'], [... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
2-Phenoxyethanol as anaesthetic in removing relocating 102 species of fishes representing from Sea World to uShaka Marine World, South Africa. | 2-Phenoxyethanol was used as an anaesthetic to translocate 102 species of fishes representing 30 families from the Sea World aquarium on Durban's beachfront to uShaka Marine World. Most fishes responded well to a final anaesthetic concentration of 0.150 ml/l and there were no mortalities. | ['Anesthetics', 'Animals', 'Ethylene Glycols', 'Female', 'Fishes', 'Male', 'Species Specificity', 'Transportation'] | 19,040,133 | [['D27.505.696.277.100', 'D27.505.954.427.210.100'], ['B01.050'], ['D02.033.455.250'], ['B01.050.150.900.493'], ['G16.824'], ['J01.937']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A regulatory network controls expression of the in vivo-expressed HreP protease of Yersinia enterocolitica. | The human enteropathogen Yersinia enterocolitica survives and replicates in the lymphoid tissues of its host. Previous in vivo analyses of gene expression revealed that various chromosomal genes are expressed at this stage of infection, but not in vitro. One of these, termed hreP, encodes a protease that is necessary f... | ['Bacterial Proteins', 'DNA Transposable Elements', 'DNA-Binding Proteins', 'Gene Deletion', 'Gene Expression Regulation, Bacterial', 'Humans', 'Membrane Proteins', 'Mutagenesis, Insertional', 'Promoter Regions, Genetic', 'Subtilisins', 'Yersinia enterocolitica'] | 19,114,497 | [['D12.776.097'], ['D13.444.308.520', 'G02.111.570.080.708.330.200', 'G05.360.080.708.330.200', 'G05.360.340.024.425.200'], ['D12.776.260'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.308.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543'], ['E05.393.420.601.550', 'G05.365.590.575', 'G05.558.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Thermal and pressure pain sensitivity in patients with unilateral shoulder pain: comparison of involved and uninvolved sides. | STUDY DESIGN: Cross-sectional.BACKGROUND: In the examination of patients with unilateral shoulder pain, pain provocation testing to compare the involved and uninvolved sides has been considered useful. However, side-to-side comparisons of experimental pain sensitivity in patients with unilateral shoulder pain are not w... | ['Analysis of Variance', 'Cross-Sectional Studies', 'Female', 'Hot Temperature', 'Humans', 'Male', 'Middle Aged', 'Pain Measurement', 'Pain Threshold', 'Pressure', 'Sex Factors', 'Shoulder Pain'] | 21,169,718 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.150.900.649.313.988.400.11... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Are psychiatric educators "losing the mind"? | Psychiatry is part of medicine, and developing competence to deal with the mental life of patients is an essential part of general medical as well as psychiatric subspecialty education. As psychiatry's neurobiological data base, therapeutic armamentarium, scope of interest, and philosophical views expand and competitiv... | ['Attitude of Health Personnel', 'Attitude to Health', 'Curriculum', 'Humans', 'Internship and Residency', 'Mental Disorders', 'Physician-Patient Relations', 'Psychiatry', 'Students, Medical', 'Teaching'] | 3,341,460 | [['F01.100.050', 'N05.300.100'], ['F01.100.150', 'N05.300.150'], ['I02.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['F03'], ['F01.829.401.650.675', 'N05.300.660.625'], ['F04.096.544', 'H02.403.690'], ['M01.848.769.602'], ['I02.903']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Alleviation of labor pain in Norway. An interview investigation in 1969 and 1986. | In 1969 the Scan-Gallup institution interviewed a random sample of 503 women from all parts of Norway who had given birth during the last 24 months. Cesarean sections and forceps deliveries were excluded. The interviews revealed that 69% of the women were left unattended for a considerable part of the delivery, that th... | ['Anesthesia, Obstetrical', 'Consumer Behavior', 'Female', 'Humans', 'Norway', 'Pregnancy'] | 2,589,040 | [['E03.155.364'], ['F01.145.236'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.816.374'], ['G08.686.784.769']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
[Influence of tobacco smoking on the development of experimental pulmonary tuberculosis]. | The present investigation was designed to the study, in rabbits, of morphologic and enzymatic pulmonary alterations produced by tobacco smoke and the course of tuberculosis under these conditions. The histologic examination revealed muciparous hyperplasia and pavementing metaplasia of the bronchic epithelium, accompani... | ['Animals', 'Chick Embryo', 'Lung', 'Rabbits', 'Smoking', 'Tuberculosis, Pulmonary'] | 188,112 | [['B01.050'], ['A13.350.150', 'A16.331.200'], ['A04.411'], ['B01.050.150.900.649.313.968.700'], ['F01.145.805'], ['C01.150.252.410.040.552.846.899', 'C01.748.939', 'C08.381.922', 'C08.730.939']] | ['Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Conformational diseases and ER stress-mediated cell death: apoptotic cell death and autophagic cell death. | The expanded polyglutamine (polyQ) tracts observed in autosomal dominant neurodegenerative disorders have the tendency to form intracellular aggregates, thus enhancing apoptotic cell death and the formation of autophagic vesicles. PolyQ accumulation inhibits the ER-associated degradation system (ERAD) resulting in redu... | ['Animals', 'Apoptosis', 'Autophagy', 'Endoplasmic Reticulum', 'Peptides', 'Protein Conformation', 'Protein Folding'] | 16,472,118 | [['B01.050'], ['G04.146.954.035'], ['G04.011'], ['A11.284.430.214.190.875.248'], ['D12.644'], ['G02.111.570.820.709'], ['G01.154.651', 'G02.111.688']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of matrix metalloproteinase-2 and -9 in synovial fluid of the temporomandibular joint accompanied by anterior disc displacement. | The purpose of this study was to determine whether or not matrix metalloproteinases (MMPs) in synovial fluid are helpful in the biochemical diagnosis of temporomandibular joint (TMJ) disorder (TMD). We examined the synovial fluid from 38 TMD patients with disc displacement and 20 volunteers by gelatin zymography and im... | ['Adolescent', 'Adult', 'Aged', 'Biomarkers', 'Case-Control Studies', 'Chi-Square Distribution', 'Electrophoresis, Polyacrylamide Gel', 'Female', 'Humans', 'Immunoblotting', 'Joint Dislocations', 'Male', 'Matrix Metalloproteinase 2', 'Matrix Metalloproteinase 9', 'Middle Aged', 'Osteoarthritis', 'Synovial Fluid', 'Temp... | 11,140,902 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.649.313.988.400.112.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The impact of listening to pleasant natural sounds on anxiety and physiologic parameters in patients undergoing coronary angiography: A pragmatic quasi-randomized-controlled trial. | OBJECTIVE: This study aimed to investigate the impact of listening to pleasant natural sounds on anxiety and physiological parameters in patients undergoing coronary angiography.METHODS: The present pragmatic quasi-randomized controlled clinical trial was conducted on 130 patients undergone elective angiography. The pa... | ['Aged', 'Anxiety', 'Blood Pressure', 'Coronary Angiography', 'Female', 'Heart Rate', 'Humans', 'Male', 'Middle Aged', 'Music Therapy', 'Stress, Psychological'] | 27,863,609 | [['M01.060.116.100'], ['F01.470.132'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E02.190.888.500', 'E02.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Expression of rab11a N124I in gastric parietal cells inhibits stimulatory recruitment of the H+-K+-ATPase. | Stimulation of the gastric parietal cell results in a massive redistribution of H+-K+-ATPase from cytoplasmic tubulovesicles to the apical plasma membrane. Previous studies have implicated the small GTPase rab11 in this process. Using matrix-assisted laser desorption mass spectrometry, we confirmed that rab11 is associ... | ['1-Methyl-3-isobutylxanthine', 'Aminopyrine', 'Animals', 'Cells, Cultured', 'Genes, Dominant', 'H(+)-K(+)-Exchanging ATPase', 'Histamine', 'Humans', 'Immunohistochemistry', 'Mutation', 'Parietal Cells, Gastric', 'Proton Pump Inhibitors', 'Rabbits', 'Tissue Distribution', 'rab GTP-Binding Proteins'] | 10,484,323 | [['D03.633.100.759.758.824.751.500'], ['D03.383.129.539.850.077'], ['B01.050'], ['A11.251'], ['G05.360.340.024.340.240', 'G05.420.320'], ['D08.811.277.040.025.314.625', 'D12.776.157.530.450.250.875.500.625', 'D12.776.157.530.813.625', 'D12.776.543.585.450.250.875.500.625', 'D12.776.543.585.813.625'], ['D02.092.211.215.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Familial primary gastric lymphoma. | Familial lymphoma is uncommon and is usually associated with various forms of hereditary immunodeficiencies. Primary gastric lymphomas that occurred in three adults from the same family, who had no overt immunodeficiency or cancer of non-lymphomatous origin, are reported. Two sisters presented with a low grade lymphoma... | ['Aged', 'Family', 'Female', 'Gastric Mucosa', 'Humans', 'Lymphoma, Non-Hodgkin', 'Male', 'Middle Aged', 'Pedigree', 'Stomach Neoplasms'] | 8,432,445 | [['M01.060.116.100'], ['F01.829.263', 'I01.880.853.150'], ['A03.556.875.875.440', 'A10.615.550.291'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480', 'C15.604.515.569.480', 'C20.683.515.761.480'], ['M01.060.116.630'], ['E05.393.673'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.249.767', 'C... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Circulating soluble endoglin modifies the inflammatory response in mice. | Inflammation is associated with every health condition, and is an important component of many pathologies such as cardiovascular diseases. Circulating levels of soluble endoglin have been shown to be higher in the serum of patients with cardiovascular diseases with a significant inflammatory component. The aim of this ... | ['Acute Lung Injury', 'Animals', 'Bronchoalveolar Lavage Fluid', 'Capillary Permeability', 'Cell Adhesion Molecules', 'Cytokines', 'Endoglin', 'Inflammation', 'Inflammation Mediators', 'Lipopolysaccharides', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred CBA', 'Mice, Transgenic'] | 29,145,462 | [['C08.381.520.500'], ['B01.050'], ['E05.927.100.500'], ['G03.143.330', 'G09.330.165'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D12.776.543.750.250'], ['C23.550.470'], ['D23.469'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interallelic class switch recombination can reverse allelic exclusion and allow trans-complementation of an IgH locus switching defect. | The predominant path of immunoglobulin class switch recombination follows the paradigm of intra-chromosomal deletion enabling expression of another heavy chain instead of micro and delta. This was, however, challenged by observations of inter-allelic class switch recombination in rabbit or mouse IgG3- or IgA-producing ... | ['Alleles', 'Animals', 'B-Lymphocytes', 'Cells, Cultured', 'Enzyme-Linked Immunosorbent Assay', 'Gene Expression Regulation', 'Immunoglobulin Class Switching', 'Immunoglobulin Heavy Chains', 'Immunoglobulin Switch Region', 'Lipopolysaccharides', 'Lymphoid Tissue', 'Mice', 'Mutation', 'Recombination, Genetic', 'Transcri... | 16,874,738 | [['G05.360.340.024.340.030'], ['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['A11.251'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['G05.308'], ['G05.344.401... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Implication of the spinal nucleus of the trigeminal nerve in acupuncture. | This voluminous nucleus extends from the upper part of the medulla oblongata to the 4th cervical segment of the spinal cord. This topography puts it in relation with numerous other spinal and cerebral centers = ventral and dorsal horns of the spinal cord, including spinal nucleus of the accessory nerve, nucleus solitar... | ['Acupuncture Therapy', 'Humans', 'Pain', 'Pain Management', 'Trigeminal Neuralgia', 'Trigeminal Nucleus, Spinal'] | 2,880,465 | [['E02.190.044'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['E02.745', 'N04.590.607.500'], ['C07.465.299.625.500.700', 'C10.292.319.625.700.700'], ['A08.186.211.132.810.428.600.650.750', 'A08.186.211.132.810.591.500.875', 'A08.186.211.132.931.920']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Erythropoietin protects myocardium against ischemia-reperfusion injury under moderate hyperglycemia. | Erythropoietin (EPO), an essential hormone for erythropoiesis, provides protection against myocardial ischemia/reperfusion (I/R) injury. Hyperglycemia during acute myocardial infarction aggravates organ damage and attenuates the efficacies of various protective measures. This study aimed to investigate the protective r... | ['Acetylation', 'Animals', 'Apoptosis', 'Cardiotonic Agents', 'Caspase 3', 'Cell Line', 'Erythropoietin', 'GATA4 Transcription Factor', 'Hyperglycemia', 'MAP Kinase Signaling System', 'Male', 'Myocardial Reperfusion Injury', 'Myocytes, Cardiac', 'Phosphorylation', 'Proto-Oncogene Proteins c-bcl-2', 'Rats', 'Rats, Sprag... | 25,446,919 | [['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['B01.050'], ['G04.146.954.035'], ['D27.505.954.411.222', 'D27.720.799.080'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['A11.251.210'], ['D12.644.276.374.410.240.1... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Melatonin receptors mediate improvements of survival in a model of polymicrobial sepsis. | OBJECTIVES: Melatonin has been demonstrated to improve survival after experimental sepsis via antioxidant effects. Yet, recent evidence suggests that this protective capacity may also rely on melatonin receptor activation. Therefore, the present study was designed to investigate whether selective melatonin receptor-ago... | ['Animals', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Indenes', 'Interleukin-10', 'Interleukin-6', 'Male', 'Melatonin', 'Mice', 'Mice, Inbred C3H', 'Mice, Knockout', 'Rats', 'Rats, Sprague-Dawley', 'Receptor, Melatonin, MT1', 'Receptor, Melatonin, MT2', 'Receptors, Melatonin', 'Sepsis', 'Tryptamine... | 24,145,838 | [['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.455.426.559.847.486', 'D04.615.486'], ['D12.644.276.374.465.510', 'D12.776.467.374.465.510', 'D23.529.374.465.510'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['D03.633.100.473... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid detection of mitochondrial sequence polymorphisms using multiplex solid-phase fluorescent minisequencing. | This work describes a novel method, multiplex solid-phase fluorescent minisequencing, for the simultaneous detection of several point mutations and/or small deletions and insertions. The method is applied to the analysis of mitochondrial DNA polymorphisms for the purposes of individual identification. A database of 152... | ['African Continental Ancestry Group', 'Base Sequence', 'DNA Primers', 'DNA, Mitochondrial', 'European Continental Ancestry Group', 'Fluorescence', 'Genetics, Population', 'Haplotypes', 'Humans', 'Molecular Sequence Data', 'Polymorphism, Genetic', 'Probability', 'Sequence Analysis, DNA', 'United Kingdom'] | 8,661,030 | [['M01.686.508.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.283.225'], ['M01.686.508.400'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['H01.158.273.343.335'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.1... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Learning individual talkers' structural preferences. | Listeners are often capable of adjusting to the variability contained in individual talkers' (speakers') speech. The vast majority of findings on talker adaptation are concerned with learning the contingency between phonological characteristics and talker identity. In contrast, the present study investigates representa... | ['Adult', 'Female', 'Humans', 'Learning', 'Linguistics', 'Male', 'Phonetics', 'Speech', 'Speech Perception', 'Young Adult'] | 22,498,776 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425', 'F02.784.629.529'], ['L01.559.598'], ['L01.559.598.518'], ['F01.145.209.908.677', 'G11.561.812', 'L01.559.423.676'], ['F02.463.593.071.875', 'G07.888.125.875'], ['M01.060.116.815']] | ['Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
A predictive model for length of Barrett's esophagus with hiatal hernia length and duration of esophageal acid exposure. | BACKGROUND: A significant correlation between the duration and height of esophageal acid exposure and the length of Barrett's mucosa has been demonstrated. The aims of this study were to determine if there is a correlation between hiatal hernia length and Barrett's esophagus length, and to develop a predictive model fo... | ['Aged', 'Barrett Esophagus', 'Biopsy', 'Esophagoscopy', 'Esophagus', 'Gastroesophageal Reflux', 'Hernia, Hiatal', 'Humans', 'Hydrogen-Ion Concentration', 'Linear Models', 'Male', 'Models, Biological', 'Monitoring, Physiologic', 'Mucous Membrane', 'Time Factors'] | 14,528,207 | [['M01.060.116.100'], ['C04.834.154', 'C06.405.117.102'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['E01.370.372.250.250.275', 'E01.370.388.250.250.250.260', 'E04.210.240.250.260', 'E04.502.250.250.250.260'], ['A03.556... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sex-specific effect of matrix metalloproteinase-9 functional promoter polymorphism on carotid artery stiffness. | BACKGROUND AND PURPOSE: Large artery stiffness is considered to be a marker for cardiovascular disease. Serum matrix metalloproteinase-9 (MMP-9) level has been found to correlate with arterial stiffness and predict cardiovascular risk. This study was aimed to investigate the relationship between the MMP-9 genotypes and... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carotid Artery Diseases', 'Carotid Artery, Common', 'Chi-Square Distribution', 'Female', 'Genetic Predisposition to Disease', 'Heterozygote', 'Homozygote', 'Humans', 'Male', 'Matrix Metalloproteinase 9', 'Menopause', 'Middle Aged', 'Multivariate Analysis', 'Phenotype', 'Polymeras... | 22,727,497 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300.200', 'C14.907.253.123'], ['A07.015.114.186.200'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380.383'], ['G05.380.554'], ['B01.050.150.900.6... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Mechanisms of pentazocine-induced ventilatory depression and antinociception in anesthetized rats. | This study was performed to clarify mechanisms underlying pentazocine-induced ventilatory depression and antinociception. Spontaneous ventilation and hind leg withdrawal response against nociceptive thermal stimulation were simultaneously recorded in anesthetized rats. Pentazocine decreased minute volume resulting from... | ['Analgesics', 'Anesthesia', 'Animals', 'Male', 'Naltrexone', 'Pentazocine', 'Rats, Wistar', 'Receptors, Opioid, kappa', 'Receptors, Opioid, mu', 'Respiratory Insufficiency'] | 27,021,234 | [['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['E03.155'], ['B01.050'], ['D03.132.577.249.706.550', 'D03.605.497.750.550', 'D03.633.400.686.750.550', 'D04.615.723.795.706.550'], ['D03.132.577.249.106.700', 'D04.615.723.795.106.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D12.776.543.750.695.620.400'... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice. | Stable gene replacement by in vivo administration of lentiviral vectors (LVs) has therapeutic potential for metabolic disorders and other systemic diseases. We studied the expression of intracellular and secreted proteins by LVs in immunocompetent mice. Liver, spleen, and bone marrow cells were efficiently transduced. ... | ['Animals', 'Factor IX', 'Genetic Therapy', 'Genetic Vectors', 'Green Fluorescent Proteins', 'Hepatocytes', 'Humans', 'Isoantibodies', 'Lentivirus', 'Liver', 'Luminescent Proteins', 'Mice', 'Mice, Transgenic', 'Promoter Regions, Genetic', 'T-Lymphocytes, Cytotoxic', 'Transduction, Genetic', 'Transgenes'] | 14,701,690 | [['B01.050'], ['D08.622.355', 'D12.776.124.125.375', 'D12.776.811.243.355', 'D23.119.375'], ['E02.095.301', 'E05.393.420.301'], ['G05.360.337'], ['D12.776.532.265'], ['A11.436.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.664', 'D12.776.124.790.651.114.664', 'D12.776.377.715.548.114.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Screening, brief intervention, and referral to treatment (SBIRT): 12-month outcomes of a randomized controlled clinical trial in a Polish emergency department. | BACKGROUND: A randomized controlled trial of screening, brief intervention, and referral to treatment (SBIRT) among at-risk (based on average number of drinks per week and drinks per drinking day) and dependent drinkers was conducted in an emergency department (ED) among 446 patients 18 and older in Sosnowiec, Poland.... | ['Adult', 'Alcohol Drinking', 'Alcoholism', 'Data Interpretation, Statistical', 'Emergency Service, Hospital', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Patient Dropouts', 'Patient Selection', 'Poland', 'Referral and Consultation', 'Sex Factors', 'Trauma Centers', 'Treatment Outcome'] | 20,659,072 | [['M01.060.116'], ['F01.145.317.269'], ['C25.775.100.250', 'F03.900.100.350'], ['E05.245.380', 'E05.318.740.300', 'L01.313.500.750.190.380', 'N05.715.360.750.300', 'N06.850.520.830.300'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Case of immediate hypersensitivity to beer. | We report here a case of immediate hypersensitivity to beer, in which a female patient developed angioedema of the eyelids shortly after consuming beer. In skin prick tests, the patient showed positive reactions to the base ingredients of beer, particularly malt and barley. The specific serum immunoglobulin E antibodie... | ['Adult', 'Beer', 'Female', 'Humans', 'Hypersensitivity, Immediate'] | 26,661,797 | [['M01.060.116'], ['G07.203.100.100.200', 'G07.203.200.250', 'J02.200.100.200', 'J02.350.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543.480']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Using uniaxial pseudorandom stress stimuli to develop soft tissue constitutive equations. | A nonlinear systems identification method was used to develop constitutive equations for soft tissue specimens under uniaxial tension. The constitutive equations are developed from a single test by applying a pseudorandom Gaussian (PGN) stress input to the specimen, measuring the resulting strain, and calculating the V... | ['Animals', 'Connective Tissue', 'Elasticity', 'Medial Collateral Ligament, Knee', 'Models, Statistical', 'Nonlinear Dynamics', 'Normal Distribution', 'Rats', 'Rats, Sprague-Dawley', 'Skin Physiological Phenomena', 'Stochastic Processes', 'Stress, Mechanical', 'Viscosity'] | 11,874,141 | [['B01.050'], ['A10.165'], ['G01.374.590'], ['A02.513.514.162.600', 'A02.835.583.512.162.600', 'A10.165.669.514.162.600'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.599.850', 'H01.548.675'], ['E05.318.740.994.500', 'G17.820.500', 'N05.715.360.750.750.565', 'N06.850.520.830.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Ocular complications after anti-vascular endothelial growth factor therapy in Medicare patients with age-related macular degeneration. | PURPOSE: To determine longitudinal rates of ocular complications after anti-vascular endothelial growth factor (VEGF) treatment for neovascular age-related macular degeneration (AMD) in a nationally representative longitudinal sample.DESIGN: Retrospective, longitudinal case-control study.METHODS: Using the Medicare 5% ... | ['Aged, 80 and over', 'Angiogenesis Inhibitors', 'Antibodies, Monoclonal', 'Antibodies, Monoclonal, Humanized', 'Aptamers, Nucleotide', 'Bevacizumab', 'Case-Control Studies', 'Endophthalmitis', 'Eye Diseases', 'Female', 'Follow-Up Studies', 'Health Services Research', 'Humans', 'Incidence', 'Intravitreal Injections', '... | 21,664,593 | [['M01.060.116.100.080'], ['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D13.695.578... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
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