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The use of opioid drugs in management of chronic orofacial pain. | The use of opioid analgesics for the management of patients with chronic pain is controversial. However, randomized and double-blind clinical trials have shown that in select groups of patients with chronic pain, the daily administration of oral opioids decreases pain levels and improves quality of life. This article p... | ['Analgesics, Opioid', 'Chronic Disease', 'Facial Pain', 'Humans', 'Opioid-Related Disorders'] | 9,734,771 | [['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['C23.550.291.500'], ['C23.888.592.612.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C25.775.643.500', 'F03.900.647.500']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Changes in sexually transmitted disease rates after HIV testing and posttest counseling, Miami, 1988 to 1989. | OBJECTIVES: The effects of posttest counseling on acquisition of sexually transmitted diseases in patients at a large urban sexually transmitted disease clinic were studied.METHODS: Comparisons were made of the percentage of patients who had a positive gonorrhea culture (or any sexually transmitted disease) in the 6 mo... | ['AIDS Serodiagnosis', 'Adolescent', 'Adult', 'Ambulatory Care Facilities', 'Child', 'Contact Tracing', 'Counseling', 'Female', 'Florida', 'Gonorrhea', 'HIV Seroprevalence', 'Health Behavior', 'Health Status Indicators', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Organizational Objectives', 'Outcome Assessment, Hea... | 8,460,729 | [['E01.370.225.812.735.060', 'E01.370.225.875.408.500', 'E05.200.812.735.060', 'E05.200.875.408.500', 'E05.478.594.760.060'], ['M01.060.057'], ['M01.060.116'], ['N02.278.035'], ['M01.060.406'], ['E05.318.270', 'N06.850.520.270', 'N06.850.780.200.225'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Clinically isolated syndromes: a new oligoclonal band test accurately predicts conversion to MS. | BACKGROUND: Patients with a clinically isolated demyelinating syndrome (CIS) are at risk of developing a second attack, thus converting into clinically definite multiple sclerosis (CDMS). Therefore, an accurate prognostic marker for that conversion might allow early treatment. Brain MRI and oligoclonal IgG band (OCGB) ... | ['Adolescent', 'Adult', 'Brain', 'Demyelinating Diseases', 'Female', 'Humans', 'Immunoglobulin G', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Multiple Sclerosis', 'Reproducibility of Results'] | 16,505,315 | [['M01.060.057'], ['M01.060.116'], ['A08.186.211'], ['C10.314'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.2... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prevalence of epilepsy in Turkish children between the ages of 0 and 16 years. | The aim of this cross-sectional study was to determine the prevalence of epilepsy in Turkey among children between the ages of 0 and 16 years. The study population consisted of 24,773,569 children living in Turkey. Because the prevalence of childhood epilepsy is reported to be 0.001 to 1% in the literature, the sample ... | ['Adolescent', 'Age Distribution', 'Child', 'Child, Preschool', 'Cross-Sectional Studies', 'Delivery, Obstetric', 'Epilepsy', 'Female', 'Health Surveys', 'Humans', 'Infant', 'Infant, Newborn', 'Male', 'Prevalence', 'Risk Factors', 'Rural Population', 'Sex Factors', 'Socioeconomic Factors', 'Surveys and Questionnaires',... | 15,163,093 | [['M01.060.057'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E04.520.252'], ['C10.228.140.490'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Cyanide and biothiols recognition properties of a coumarin chalcone compound as red fluorescent probe. | A novel coumarin chalcone derivative 1 was designed, synthesized and characterized by nuclear magnetic resonance spectra and high resolution mass spectrum. The photophysical and recognition properties of the compound as red fluorescent probe for cyanide and biothiols including cysteine (Cys), homocysteine (Hcy) and glu... | ['Coumarins', 'Cyanides', 'Fluorescent Dyes', 'Spectrophotometry, Ultraviolet', 'Sulfhydryl Compounds'] | 30,064,116 | [['D03.383.663.283.446', 'D03.633.100.150.446'], ['D01.248.497.158.291', 'D01.625.400.100'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['D02.886.489']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Build a better mouse: directly-observed issues in computer use for adults with SMI. | Integrating information technology into healthcare has the potential to bring treatment to hard-to-reach people. Individuals with serious mental illness (SMI), however, may derive limited benefit from these advances in care because of lack of computer ownership and experience. To date, conclusions about the computer sk... | ['Adult', 'Ambulatory Care', 'Attitude to Computers', 'Cocaine-Related Disorders', 'Computer Literacy', 'Computer Peripherals', 'Computers', 'Consumer Health Information', 'Diagnosis, Dual (Psychiatry)', 'Educational Status', 'Female', 'Health Services Accessibility', 'Humans', 'Internet', 'Male', 'Mental Disorders', '... | 22,711,454 | [['M01.060.116'], ['E02.760.106', 'N02.421.585.106'], ['F01.100.100'], ['C25.775.300', 'F03.900.300'], ['L01.143.256'], ['L01.224.230.260.115'], ['L01.224.230.260'], ['I02.233.332.186', 'N02.421.726.407.229'], ['E01.190'], ['N01.824.196'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 |
Characterization of toxicological properties of L-lysine polymers in CD-1 mice. | We recently showed that polylysine, the polymer of lysines, retains anti-prion activity. Although the effectiveness of prion inhibition by polylysine was demonstrated with the regimen tolerated in mice, a determination of quantitative polylysine toxicity is necessary to precisely address the in vivo toxicity level of p... | ['Animals', 'Blood Chemical Analysis', 'Body Weight', 'Mice', 'Platelet Count', 'Polylysine'] | 23,711,515 | [['B01.050'], ['E01.370.225.124.100', 'E05.200.124.100'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.225.500.195.107.740', 'E01.370.225.625.107.700', 'E01.370.225.625.625.625', 'E05.200.500.1... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Perfluorinated and chlorinated pollutants as predictors of demographic parameters in an endangered seabird. | Despite global occurrence of several perfluorinated compounds (PFCs) the potential ecological effects of such substances on natural populations are not known. In endangered lesser black-backed gulls (Larus fuscus fuscus) on the Norwegian Coast, the blood concentrations of PFCs were as high as legacy organochlorines (OC... | ['Animal Migration', 'Animals', 'Charadriiformes', 'Conservation of Natural Resources', 'Ecology', 'Environmental Monitoring', 'Environmental Pollutants', 'Fluorine Compounds', 'Hydrocarbons, Chlorinated', 'Norway', 'Population Dynamics', 'Reproduction'] | 18,329,768 | [['F01.145.113.069.500'], ['B01.050'], ['B01.050.150.900.248.150'], ['J01.256', 'N06.230.080'], ['H01.158.273.248', 'H01.277.249'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D27.888.284'], ['D01.303'], ['D02.455.526.439'], ['Z01.542.816.374'], ['I01.240.600', 'N01.224.625', 'N06.850.505.400.700'], ['G08.686.784']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 |
Monoclonal antibodies for carcinoembryonic antigen (CEA) as a model system: identification of two novel CEA-related antigens in meconium and colorectal carcinoma tissue by Western blots and differential immunoaffinity chromatography. | In a previous study, five monoclonal antibodies against the carcinoembryonic antigen (CEA) with different epitope specificities were delineated. One of these antibodies which exhibits a high affinity for CEA binds to different carcinoma tissues, to liver tissue, and to granulocytes. This antibody was selected for the i... | ['Antibodies, Monoclonal', 'Binding Sites, Antibody', 'Carcinoembryonic Antigen', 'Carcinoma', 'Chromatography, Affinity', 'Collodion', 'Colonic Neoplasms', 'Electrophoresis, Polyacrylamide Gel', 'Humans', 'Meconium', 'Models, Biological', 'Molecular Weight', 'Paper', 'Rectal Neoplasms'] | 4,045,198 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G02.111.570.060.425.079', 'G02.111.570.120.408', 'G12.122.232', 'G12.125'], ['D12.776.395.550.200.210', 'D12.776.543.550.200.210', 'D23.050.285.329', 'D23.050.301.350.210', 'D23.101.140.300'], ['C04.557.470.200'], ['E05.19... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Rat striatal acetylcholinesterase inhibition by fasciculin (a polypeptide from green mamba snake venom). | It has been shown that Fasciculins (FAS), polypeptides isolated from the venom of the green mamba Dendroaspis angusticeps, provoke a powerful inhibition of peripheral acetylcholinesterase (AChE). In the present study, 0.5 microliter of increasing concentrations (10-500 micrograms/ml) of FAS were injected into the stria... | ['Acetylcholinesterase', 'Animals', 'Cholinesterase Inhibitors', 'Corpus Striatum', 'Elapid Venoms', 'Histocytochemistry', 'Male', 'Rats'] | 3,601,220 | [['D08.811.277.352.100.170.176'], ['B01.050'], ['D27.505.519.389.275', 'D27.505.519.625.120.300', 'D27.505.696.577.120.300'], ['A08.186.211.200.885.287.249.487'], ['D20.888.850.325', 'D23.946.833.850.325'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Increased myofiber remodelling and NFATc1-myonuclear translocation in rat postural skeletal muscle after experimental vestibular deafferentation. | BACKGROUND: The vestibular system undergoes considerable modification during spaceflight [5]. This is paralleled by microgravity-induced muscle atrophy [6]. However, the possibility of vestibulo-autonomic regulatory mechanisms affecting skeletal muscle structure and function have not yet been addressed.OBJECTIVE: We hy... | ['Anatomy, Cross-Sectional', 'Animals', 'Biomarkers', 'Cell Size', 'Denervation', 'Ear, Inner', 'Female', 'Immunohistochemistry', 'Muscle Fibers, Skeletal', 'Muscle, Skeletal', 'Phenotype', 'Rats', 'Rats, Sprague-Dawley', 'Signal Transduction', 'Transcription Factors', 'Vestibule, Labyrinth', 'Weightlessness', 'Weightl... | 24,284,598 | [['H01.158.100.185'], ['B01.050'], ['D23.101'], ['G04.325'], ['E04.525.210'], ['A09.246.300'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.... | ['Disciplines and Occupations [H]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Computational analysis of glycoside hydrolase family 1 specificities. | Glycoside hydrolase family 1 consists of beta-glucosidases, beta-galactosidases, 6-phospho-beta-galactosidases, myrosinases, and other enzymes having similar primary and tertiary structures but diverse specificities. Among these enzymes, beta-glucosidases hydrolyze cellobiose to glucose, and therefore they are key play... | ['Amino Acid Sequence', 'Carbohydrate Conformation', 'Disaccharides', 'Glycoside Hydrolases', 'Protein Structure, Tertiary', 'Substrate Specificity'] | 18,615,662 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.820.235'], ['D09.698.629.305', 'D09.947.750'], ['D08.811.277.450'], ['G02.111.570.820.709.610'], ['G02.111.835']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of caponization and exogenous androgens implantation on blood lipid and lipoprotein profile in male chickens. | This study investigated effects of caponization and different forms of androgen implantation on blood lipid and lipoprotein profile of capons to understand the role of different androgens. Male chickens were caponized at 12 wk of age and selected at 16 wk of age for a 10-wk feeding period. Sixteen intact caponized (cap... | ['Androgens', 'Animals', 'Chickens', 'Estradiol', 'Fatty Acids, Nonesterified', 'Female', 'Lipids', 'Lipoprotein Lipase', 'Lipoproteins', 'Lipoproteins, HDL', 'Lipoproteins, LDL', 'Lipoproteins, VLDL', 'Male', 'Orchiectomy', 'Phospholipids', 'Testosterone', 'Triglycerides'] | 20,371,844 | [['D27.505.696.399.472.161'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D10.251.310'], ['D10'], ['D08.811.277.352.100.430'], ['D10.532', 'D12.776.521'], ['D10.532.432', 'D12.776.521.479'], ['D10.532.515', 'D12.776.521.550'], ['... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A retrospective study of gymnastics injuries to competitors and noncompetitors in private clubs. | The purpose of this study was to determine the number and types of injuries which occur to competitive and noncompetitive gymnasts in private clubs. Secondary purposes were to determine which events were most hazardous, and whether or not the ratio between participant and instructor, the availability of safety equipmen... | ['Athletic Injuries', 'Contusions', 'Equipment Safety', 'Female', 'Gymnastics', 'Humans', 'Male', 'Organizations', 'Retrospective Studies', 'Sprains and Strains', 'United States'] | 7,125,046 | [['C26.115'], ['C26.974.250'], ['E05.330'], ['G11.427.410.698.277.156', 'I03.350.156', 'I03.450.642.845.417'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.540'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.500.500',... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Long-term results after partial left ventriculectomy. | BACKGROUND: Long-term clinical, echocardiographic and hemodynamic effects after partial left ventriculectomy (PLV) and predictors of outcome have been determined.METHODS: Between January 1995 and July 1999, PLV was performed in 39 patients. In 15 patients the etiology of heart failure was idiopathic dilated cardiomyopa... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cardiac Surgical Procedures', 'Female', 'Heart Failure', 'Heart Ventricles', 'Hemodynamics', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Prospective Studies', 'Survival Analysis', 'Time Factors', 'Treatment Outcome'] | 12,767,546 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.100.376', 'E04.928.220'], ['C14.280.434'], ['A07.541.560'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['E05.318.372.500.750.62... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Complex approach for analysis of snake venom á-neurotoxins binding to HAP, the high-affinity peptide. | Snake venom á-neurotoxins, invaluable pharmacological tools, bind with high affinity to distinct subtypes of nicotinic acetylcholine receptor. The combinatorial high-affinity peptide (HAP), homologous to the C-loop of á1 and á7 nAChR subunits, binds biotinylated á-bungarotoxin (áBgt) with nanomolar affinity and might b... | ['Bungarotoxins', 'Cobra Neurotoxin Proteins', 'Molecular Dynamics Simulation', 'Neurotoxins', 'Peptides', 'Protein Binding', 'Protein Structure, Secondary', 'alpha7 Nicotinic Acetylcholine Receptor'] | 32,123,252 | [['D20.888.850.325.139', 'D23.946.833.850.325.139'], ['D12.776.831.244', 'D20.888.850.325.200', 'D23.946.833.850.325.200'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D27.888.569.504'], ['D12.644'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.600'], ['D12.776.157.530.400.400.100.500.500', 'D12.7... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Astrocytes follow ganglion cell axons to establish an angiogenic template during retinal development. | Immature astrocytes and blood vessels enter the developing mammalian retina at the optic nerve head and migrate peripherally to colonize the entire retinal nerve fiber layer (RNFL). Retinal vascularization is arrested in retinopathy of prematurity (ROP), a major cause of bilateral blindness in children. Despite their i... | ['Animals', 'Astrocytes', 'Axons', 'Basic Helix-Loop-Helix Transcription Factors', 'Diphtheria Toxin', 'Eye Proteins', 'Female', 'Glial Fibrillary Acidic Protein', 'Green Fluorescent Proteins', 'Homeodomain Proteins', 'Humans', 'Male', 'Mice', 'Mice, Transgenic', 'Mutation', 'Neovascularization, Physiologic', 'Nerve Ti... | 28,722,174 | [['B01.050'], ['A08.637.200', 'A11.650.200'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['D12.776.260.103', 'D12.776.930.125'], ['D08.811.913.400.725.115.220', 'D23.946.123.305'], ['D12.776.306'], ['D05.750.078.593.400', 'D12.776.220.475.400'], ['D12.776.532.265'], ['D12.776.260.400'], [... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Delirium in patients with cancer: nursing assessment and intervention. | Delirium has been found to occur in 25% to 40% of patients with cancer at some time during their illness and has been reported to be as high as 85% in patients with advanced disease. The cognitive and behavioral changes associated with delirium cause emotional distress to the patient and family. More seriously, deliriu... | ['Attention', 'Cognition', 'Delirium', 'Humans', 'Memory', 'Neoplasms', 'Nursing Diagnosis', 'Oncology Nursing', 'Orientation', 'Patient Care Planning', 'Quality of Life', 'Thinking'] | 2,399,166 | [['F02.830.104.214'], ['F02.463.188'], ['C10.597.606.337.500', 'C23.888.592.604.339.500', 'F01.700.250.500', 'F03.615.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['C04'], ['N04.590.233.508.480.110'], ['H02.478.676.605', 'N02.421.533.600'], ['F01.058.577', 'F02.830.606'], ['N04.590.233.6... | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
Measuring the kinetics of mRNA transcription in single living cells. | The transcriptional activity of RNA polymerase II (Pol II) is a dynamic process and therefore measuring the kinetics of the transcriptional process in vivo is of importance. Pol II kinetics have been measured using biochemical or molecular methods. In recent years, with the development of new visualization methods, it ... | ['Actins', 'Cell Line, Tumor', 'DNA', 'Fluorescence Recovery After Photobleaching', 'Humans', 'Kinetics', 'Lac Operon', 'RNA Polymerase II', 'RNA, Messenger', 'Single-Cell Analysis', 'Transcription, Genetic', 'Transfection'] | 21,904,295 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['A11.251.210.190', 'A11.251.860.180'], ['D13.444.308'], ['E05.196.712.516.600.393'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['G05.360.340.024.686.545', 'G05.360.340.358.207.500.545'], ['D08.811.913.696.445... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Liquid crystal thermometry for the detection of neonatal hypothermia in Nepal. | We assessed the sensitivity, specificity and likelihood ratio of a low cost liquid crystal strip thermometer (LCT) compared with axillary mercury thermometry for the detection of neonatal hypothermia in Nepal. The subjects were 76 healthy newborns in the government maternity hospital of Kathmandu, Nepal in winter. The ... | ['Female', 'Humans', 'Hypothermia', 'Infant, Newborn', 'Likelihood Functions', 'Male', 'Nepal', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Thermometers'] | 9,538,600 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.119.565'], ['M01.060.703.520'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.360.750.625.450', 'N06.850.520.830.500.475', 'N06.850.520.830.600.400'], ['Z01.252.245.674'], ['E05.318.370.725', 'E05.337.851... | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
PTX-sensitive G proteins and permissive action of prostacyclin in newborn pig cerebral circulation. | The present study of newborn pig cerebral circulation investigated the role of pertussis toxin (PTX)-sensitive GTP binding proteins in the permissive action of prostacyclin in specific dilator responses. Pial arterioles of anesthetized piglets were observed through closed cranial windows. The piglets were treated topic... | ['8,11,14-Eicosatrienoic Acid', 'Adenylate Cyclase Toxin', 'Animals', 'Animals, Newborn', 'Arterioles', 'Carbon Dioxide', 'Cerebrovascular Circulation', 'Cyclic AMP', 'Endothelium, Vascular', 'GTP-Binding Proteins', 'Hydrogen-Ion Concentration', 'Iloprost', 'Indomethacin', 'Models, Cardiovascular', 'Muscle, Smooth, Vas... | 9,688,922 | [['D10.251.355.255.207'], ['D08.811.520.650.200.040', 'D23.946.123.946.040', 'D23.946.896.980.040'], ['B01.050'], ['B01.050.050.282'], ['A07.015.114.060', 'A07.015.461.080'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['G09.330.100.159'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Retention of polarization signatures in SHG microscopy of scattering tissues through optical clearing. | Polarization responses in Second Harmonic Generation (SHG) imaging microscopy are a valuable method to quantify aspects of tissue structure, and may be a means to differentiate normal and diseased tissues. Due to multiple scattering, the polarization data is lost in turbid tissues. Here we investigate if this informati... | ['Algorithms', 'Computer Simulation', 'Image Enhancement', 'Light', 'Microscopy, Fluorescence', 'Models, Biological', 'Nephelometry and Turbidimetry', 'Refractometry', 'Scattering, Radiation'] | 19,333,348 | [['G17.035', 'L01.224.050'], ['L01.224.160'], ['E01.370.350.600.350', 'L01.224.308.380'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E01.370.350.515.458', 'E05.595.458'], ['E05.599.395'], ['E05.196.712.650'], ['E05.196.808', 'H01.671.617.755'], ['E05.196.822', 'G01.867']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
The functional SLC11A1 gene polymorphisms are associated with sarcoidosis in Turkish population. | Sarcoidosis (SA) is an immune-mediated multisystemic disorder of unknown etiology characterized by the accumulation of lymphocytes, mononuclear phagocytes and epithelioid cell granulomas involved in different organs and tissues. The belief that genetics contribute to SA etiology is supported by twin studies, disease cl... | ['Adult', 'Aged', 'Case-Control Studies', 'Cation Transport Proteins', 'Female', 'Gene Frequency', 'Genetic Association Studies', 'Genetic Predisposition to Disease', 'Haplotypes', 'Humans', 'Male', 'Middle Aged', 'Polymorphism, Genetic', 'Sarcoidosis', 'Tuberculin Test', 'Turkey', 'Young Adult'] | 22,160,516 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['D12.776.157.530.450.250', 'D12.776.543.585.450.250'], ['G05.330'], ['E05.393.385'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Randomized double-blind placebo-controlled trial of homoeopathic 'proving' for Belladonna C30. | Homoeopathic drug pictures are developed by recording the symptomatic effects of homoeopathic remedies given to healthy volunteers (a 'proving'). In a double-blind randomized controlled trial we tested the hypothesis that individuals using an infinitesimal dilution of Belladonna (thirtieth potency, C30) would record mo... | ['Adult', 'Belladonna Alkaloids', 'Double-Blind Method', 'Drug Evaluation', 'Female', 'Homeopathy', 'Humans', 'Male', 'Surveys and Questionnaires', 'Toothache', 'Xerophthalmia'] | 10,325,874 | [['M01.060.116'], ['D03.132.760.180', 'D03.132.889.180'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E05.290.625', 'E05.337.425'], ['E02.190.388'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['C07.793.9... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Disappearance of myocardial bridging of the left anterior descending coronary artery after inferior myocardial infarction. | Myocardial bridging (MB) is defined as the intramural course of a major epicardial coronary artery, and is mostly confined to the left ventricle and the left anterior descending coronary artery (LAD). MB is a common congenital abnormality of a coronary artery, and is usually thought to be a benign anatomical variant. A... | ['Chest Pain', 'Coronary Angiography', 'Coronary Vessel Anomalies', 'Diagnosis, Differential', 'Electrocardiography', 'Heart Defects, Congenital', 'Heart Ventricles', 'Humans', 'Male', 'Middle Aged', 'Myocardial Bridging', 'Myocardial Infarction'] | 24,899,486 | [['C23.888.592.612.233'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.240.400.210', 'C14.280.400.210', 'C16.131.240.400.210'], ['E01.171'], ['E01.370.370.380.240', 'E01.370.405.240'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['A07.541.560'], ['B01.05... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Investigations on the conjunctival goblet cells and on the characteristics of glands associated with the eye in the guinea pig. | OBJECTIVE: To investigate the distribution and density of conjunctival goblet cells (GC) and to study the anatomy and microscopic characteristics of glands associated with the eye in the guinea pig.PROCEDURES: Twenty-five guinea pigs were used. Meibomian gland openings were counted using biomicroscopy. Conjunctiva, eye... | ['Animals', 'Cell Count', 'Conjunctiva', 'Eyelids', 'Goblet Cells', 'Guinea Pigs', 'Harderian Gland', 'Lacrimal Apparatus', 'Meibomian Glands', 'Sebaceous Glands', 'Tears'] | 21,199,277 | [['B01.050'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A09.371.060.200', 'A09.371.337.168'], ['A01.456.505.420.504', 'A09.371.337'], ['A03.556.124.369.320', 'A04.329.597.320', 'A04.531.520.320', 'A04.760.259', 'A10.615.550.444.321', 'A10.615.550.760.520.320', 'A10.615.550.760.600.320', 'A... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Using a Brief Parent-Report Measure to Track Outcomes for Children and Teens with Internalizing Disorders. | The Pediatric Symptom Checklist (PSC) is a widely-used, parent-completed measure of children's emotional and behavioral functioning. Previous research has shown that the PSC and its subscales are generally responsive to patient progress over the course of psychiatric treatment. In this naturalistic study, we examined t... | ['Adolescent', 'Anxiety Disorders', 'Checklist', 'Child', 'Defense Mechanisms', 'Depressive Disorder', 'Female', 'Humans', 'Male', 'Parents', 'Psychotherapy', 'Treatment Outcome'] | 25,476,666 | [['M01.060.057'], ['F03.080'], ['N05.715.360.300.179'], ['M01.060.406'], ['F01.393'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.500.320', 'I01.880.853.150.500.340', 'M01.620'], ['F04.754'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[A case of hydatidiform mole with an unclear clinical picture]. | The authors presented the case of hydatidiform mole with unclear clinical picture. They discussed clinical difficulties in the diagnosing of that lesion, and stressed the role of US method in establishing the specific final diagnosis. | ['Adult', 'Female', 'Humans', 'Hydatidiform Mole', 'Pregnancy', 'Ultrasonography'] | 1,364,995 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.955.416.812', 'C04.850.908.416.750', 'C13.703.720.949.416.875'], ['G08.686.784.769'], ['E01.370.350.850']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Scintigraphic image in a case of atypical presentation of Burkitt lymphoma. The role of the scintigraphy with 67Ga SPECT in the diagnosis and post-treatment control]. | We present a case of Burkitt's disease with bone (thoracic wall, femur) and lymph node involvement. The patient had symptoms of fever with thoracic wall and femur pain. Lymph node involvement was detected by clinical exploration. A chest X-ray showed rib abnormalities. 99mTc-DPD scan showed thoracic wall (one rib) and ... | ['Adolescent', 'Burkitt Lymphoma', 'Gallium Radioisotopes', 'Humans', 'Male', 'Tomography, Emission-Computed, Single-Photon'] | 15,000,943 | [['M01.060.057'], ['C01.925.256.466.313.165', 'C01.925.928.313.165', 'C04.557.386.480.150.165', 'C15.604.515.569.480.150.165', 'C20.683.515.761.480.150.165'], ['D01.268.556.289.500.400', 'D01.496.360.400', 'D01.496.749.360', 'D01.552.544.289.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.350.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Magnetic phases of cobalt atomic clusters on tungsten. | First-principle calculations are employed to show that the magnetic structure of small atomic clusters of Co, formed on a crystalline W(110) surface and containing 3-12 atoms, strongly deviates from the usual stable ferromagnetism of Co in other systems. The clusters are ferri-, ferro- or non-magnetic, depending on clu... | ['Alloys', 'Cobalt', 'Crystallography, X-Ray', 'Magnets', 'Models, Theoretical', 'Spin Labels', 'Tungsten'] | 23,221,372 | [['D01.552.033', 'D25.058', 'J01.637.051.058'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['E05.196.309.742.225'], ['J01.637.507'], ['E05.599'], ['D02.389.678'], ['D01.268.556.887', 'D01.268.956.882', 'D01.552.544.887']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The vulnerable, rapidly growing thoracic spine of the adolescent. | The upper and lower surface of the vertebral bodies are covered with a thick cartilaginous plate in which the secondary ossification centres develop at puberty and continue to grow throughout adolescence. Congenital indentations in the cartilaginous plates are not uncommon and they constitute regions of diminished resi... | ['Adolescent', 'Female', 'Humans', 'Intervertebral Disc', 'Intervertebral Disc Displacement', 'Kyphosis', 'Male', 'Scheuermann Disease', 'Thoracic Vertebrae'] | 2,382,179 | [['M01.060.057'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.165.308.410', 'A02.835.232.834.432', 'A10.165.382.350.050'], ['C05.116.900.307', 'C23.300.707.952'], ['C05.116.900.800.500'], ['C05.116.821.500.500', 'C05.116.900.800.500.500', 'C05.116.900.808.500'], ['A02.835.232.834.892']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Small lymphocytic lymphoma. | The clinical course of 54 patients with small lymphocytic lymphoma (SL) was reviewed. The majority of patients had disseminated lymphoma at the time of diagnosis; 14 patients (26%) presented with Ann Arbor stage I and II disease. Five- and 10-year survival for all patients was 76% and 49%. The only clinicopathologic fe... | ['Actuarial Analysis', 'Female', 'Humans', 'Leukemia, Lymphocytic, Chronic, B-Cell', 'Lymph Nodes', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Prognosis'] | 2,651,577 | [['E05.318.740.100', 'N05.715.360.750.100', 'N06.850.520.830.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337.428.080.125', 'C15.604.515.560.080.125', 'C20.683.515.528.080.125'], ['A10.549.400', 'A15.382.520.604.412'], ['M01.060.116.630'], ['E01.789.625'], ['E01.789']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A self-reference PRF-shift MR thermometry method utilizing the phase gradient. | In magnetic resonance (MR) imaging, the most widely used and accurate method for measuring temperature is based on the shift in proton resonance frequency (PRF). However, inter-scan motion and bulk magnetic field shifts can lead to inaccurate temperature measurements in the PRF-shift MR thermometry method. The self-ref... | ['Magnetic Resonance Imaging', 'Protons', 'Reference Standards', 'Thermometers'] | 22,094,444 | [['E01.370.350.825.500'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['E05.978.808'], ['E07.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lactate has the potential to promote hydrogen sulphide formation in the human colon. | High concentrations of sulphide are toxic for the gut epithelium and may contribute to bowel disease. Lactate is a favoured cosubstrate for the sulphate-reducing colonic bacterium Desulfovibrio piger, as shown here by the stimulation of sulphide formation by D. piger DSM749 by lactate in the presence of sulphate. Sulph... | ['Bacteria', 'Butyrates', 'Coculture Techniques', 'Colon', 'Humans', 'Hydrogen Sulfide', 'Lactic Acid'] | 19,732,152 | [['B03'], ['D02.241.081.114', 'D10.251.400.143'], ['E05.481.500.374'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.029.260.340', 'D01.362.350', 'D01.875.350'], ['D02.241.511.459.450']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The ultrastructure and computer imaging of the lymphatic stomata in the human pelvic peritoneum. | The lymphatic stomata in the pelvic peritoneum of human fetuses and mature mice were initially observed and studied quantitatively by using computer image processing (C.I.P.) attached to a scanning electron microscope (SEM). Two types of mesothelial cells were found in the pelvic peritoneum of human fetuses and mature ... | ['Animals', 'Epithelial Cells', 'Fetus', 'Humans', 'Lymphatic System', 'Mice', 'Microscopy, Electron, Scanning', 'Microvilli', 'Peritoneum'] | 9,229,075 | [['B01.050'], ['A11.436'], ['A16.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A15.382.520'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['A11.284.180.565'], ['A01.923.047.025.600', 'A10.615.789.596']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of vitamin D supplementation in improving disease activity in rheumatoid arthritis: An exploratory study. | AIM: The aim of this exploratory study is to estimate the relationship between vitamin D (vit D) deficiency and active rheumatoid arthritis (RA), and the role of supplementation in improving disease activity.METHOD: A randomized recruitment, consent screening, open-label interventional study was conducted in patients w... | ['Adult', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'Dietary Supplements', 'Female', 'Humans', 'India', 'Male', 'Middle Aged', 'Severity of Illness Index', 'Time Factors', 'Treatment Outcome', 'Vitamin D', 'Vitamin D Deficiency'] | 26,481,198 | [['M01.060.116'], ['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['G07.203.300.456', 'J02.500.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['M01.060.116.630'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
[A retrospective analysis of clinicopathological characteristics and prognostic factors of gastric stump cancer]. | OBJECTIVE: To explore the clinicopathological characteristics and prognostic factors of gastric stump cancer(GSC).METHODS: The clinical data of 138 patients with GSC treated from January 1992 to July 2008 were reviewed and analyzed. The patients included 122 males and 16 females with a mean age of 61.5 years, and the m... | ['Female', 'Follow-Up Studies', 'Gastric Stump', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Prognosis', 'Retrospective Studies', 'Stomach Neoplasms'] | 21,609,561 | [['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A03.556.875.875.578'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['M01.060.116.630'], ['E01.789'], ['E05.318.372.500.500.500', 'E05.318.372.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effects of cervical headgear with an expanded inner bow in the permanent dentition. | In this study, the effects of cervical headgear (CHG) use on the transverse dimension of the maxillary dental arch were evaluated in patients in the permanent dentition. Thirteen girls and 12 boys (mean age: 13.41 +/- 0.52 years) with a bilateral full cusp Class II molar relationship comprised the study group. Fifteen ... | ['Adolescent', 'Case-Control Studies', 'Cephalometry', 'Dental Arch', 'Dentition, Permanent', 'Extraoral Traction Appliances', 'Female', 'Humans', 'Jaw Relation Record', 'Male', 'Malocclusion, Angle Class II', 'Maxilla', 'Orthodontic Appliance Design', 'Orthodontics, Corrective', 'Palatal Expansion Technique', 'Statist... | 18,678,761 | [['M01.060.057'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E01.370.600.024.250', 'E05.041.250', 'N06.850.505.200.100.300'], ['A02.835.232.781.324.502.320', 'A14.521.320'], ['A14.549.167.237'], ['E06.658.453.578.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E06.520'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Molecular structure-affinity relationship of natural polyphenols for bovine ã-globulin. | SCOPE: The aim of this study was to investigate the interaction between polyphenols and bovine ã-globulin.METHODS AND RESULTS: The relationship between the structural properties of natural polyphenols and their affinities for bovine ã-globulin were investigated by fluorescence titration analysis. Methylation of hydroxy... | ['Animals', 'Catechin', 'Cattle', 'Flavonoids', 'Glycosylation', 'Hydrogenation', 'Hydroxylation', 'Molecular Structure', 'Phenols', 'Polyphenols', 'Protein Binding', 'Resveratrol', 'Spectrometry, Fluorescence', 'Stilbenes', 'Structure-Activity Relationship', 'gamma-Globulins'] | 21,225,618 | [['B01.050'], ['D03.383.663.283.240.190', 'D03.383.663.283.266.450.206', 'D03.633.100.150.240.190', 'D03.633.100.150.266.450.206'], ['B01.050.150.900.649.313.500.380.271'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['G02.111.380', 'G02.607.324', 'G03.409'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Disruption of cGMP production in pulmonary arteries isolated from fetal lambs with pulmonary hypertension. | Ligation of the ductus arteriosus of the fetal sheep produces severe pulmonary hypertension at birth. Standard tissue bath techniques were used to study third- and fourth-generation pulmonary arteries and veins isolated from fetal sheep with pulmonary hypertension created by ligation of the ductus arteriosus 11-12 days... | ['Animals', 'Atrial Natriuretic Factor', 'Cyclic GMP', 'Ductus Arteriosus', 'Fetus', 'Hypertension, Pulmonary', 'Ligation', 'Nitric Oxide', 'Nitroprusside', 'Pulmonary Artery', 'Sheep', 'Vasoconstriction', 'Vasodilator Agents'] | 7,733,349 | [['B01.050'], ['D06.472.699.584.500', 'D12.644.548.585.500'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['A07.541.278.395', 'A16.378.303.395'], ['A16.378'], ['C08.381.423', 'C14.907.489.556'], ['E04.426'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Medical Response to the Tianjin Explosions: Lessons Learned. | BACKGROUND: On August 12, 2015, a hazardous chemical explosion occurred in the Tianjin Port of China. The explosions resulted in 165 deaths, 8 missing people, injuries to thousands of people. We present the responses of emergency medical services and hospitals to the explosions and summarize the lessons that can be lea... | ['Chemical Hazard Release', 'China', 'Emergency Medical Services', 'Explosions', 'Humans', 'Mass Casualty Incidents', 'Retrospective Studies', 'Surge Capacity', 'Time Factors', 'Urban Population'] | 29,198,239 | [['N06.850.135.195'], ['Z01.252.474.164'], ['N02.421.297'], ['N06.230.208'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.198.240.856.800.537', 'I01.880.735.900.800.575', 'N06.230.100.160'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N... | ['Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
[Arthroscopic anterior capsular release in medial contracture of the shoulder secondary to brachial plexus birth palsy. Preliminary results]. | PURPOSE OF THE STUDY: Retraction of the shoulder in internal rotation is observed in 25% of children with brachial plexus birth palsy (C5, C6 +/- C7). Early bone and joint deformities affecting the glenohumeral joint are the consequences. The stiff internal rotation requires surgical release which can involve the capsu... | ['Arthroscopy', 'Brachial Plexus Neuropathies', 'Child', 'Child, Preschool', 'Contracture', 'Humans', 'Paralysis, Obstetric', 'Shoulder'] | 18,984,121 | [['E01.370.388.250.070', 'E04.502.250.070', 'E04.555.113'], ['C10.668.829.100'], ['M01.060.406'], ['M01.060.406.448'], ['C05.550.323', 'C05.651.197'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.614.131.587', 'C26.141.587'], ['A01.378.800.750']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Annual changes in serum calcium and inorganic phosphate levels and correlation with gonadal status of a freshwater murrel, Channa punctatus (Bloch). | Adult Channa punctatus murrels of both sexes (60-80 g) were collected locally from Ramgarh Lake during the second week of every month (10 individuals of each sex/month) throughout the year. Blood samples were collected and analyzed for serum calcium and phosphate levels by the methods of Trinder (1960) and Fiske and Su... | ['Animals', 'Calcium', 'Female', 'Fishes', 'Fresh Water', 'Gonads', 'Male', 'Ovary', 'Periodicity', 'Phosphates', 'Reproduction', 'Seasons', 'Sexual Maturation', 'Testis'] | 9,777,013 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.493'], ['G16.500.275.280', 'N06.230.232'], ['A05.360.576', 'A06.300.312'], ['A05.360.319.114.630', 'A05.360.576.497', 'A06.300.312.497'], ['G01.910.645', 'G07.180.562'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.695.625... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
De novo correction of mass measurement error in low resolution tandem MS spectra for shotgun proteomics. | We report an algorithm designed for the calibration of low resolution peptide mass spectra. Our algorithm is implemented in a program called FineTune, which corrects systematic mass measurement error in 1 min, with no input required besides the mass spectra themselves. The mass measurement accuracy for a set of spectra... | ['Algorithms', 'Calibration', 'Models, Molecular', 'Peptide Fragments', 'Peptide Mapping', 'Proteomics', 'Saccharomyces cerevisiae Proteins', 'Sensitivity and Specificity', 'Tandem Mass Spectrometry'] | 23,007,965 | [['G17.035', 'L01.224.050'], ['E05.978.155'], ['E05.599.595'], ['D12.644.541'], ['E05.196.181.400.454.720', 'E05.196.401.319.720', 'E05.196.700', 'E05.393.760.705.685'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.181.122.738'], ['D12.776.354.750'], ['E05.318.370.800', 'E05.318.740.87... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Peripheral blood phagocyte CD14 and CD11b expression on admission to hospital in relation to mortality among patients with community-acquired infection. | OBJECTIVE AND DESIGN: Prognostic value of markers of systemic inflammation were evaluated in patients admitted to hospital.MATERIAL: The study comprises 327 patients with community- acquired infection verified on admission (n=290) or within 3-day follow-up (n=37).METHODS: On-admission levels of phagocyte CD11b/CD18 and... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'CD11b Antigen', 'Community-Acquired Infections', 'Female', 'Hospitalization', 'Humans', 'Lipopolysaccharide Receptors', 'Male', 'Middle Aged', 'Patient Admission', 'Phagocytes', 'Survival Rate', 'Time Factors'] | 16,283,111 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.395.550.200.074.750', 'D12.776.543.550.200.093.750', 'D12.776.543.750.705.408.100.150', 'D12.776.543.750.705.833.062', 'D23.050.301.350.074.049'], ['C01.234'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
New biochemical insight of conserved water molecules at catalytic and structural Zn2+ | Human matrix metalloproteinase (MMP)-1 or collagenase-1 plays a significant role in embryonic development, tissue remodeling, and is also involved in several diseases like arthritis, metastasis, etc. Molecular dynamics simulation studies on hMMP-1 X-ray structures (PDB Id. 1CGE, 1CGF, 1CGL, 1HFC, and 2TCL) suggest that... | ['Binding Sites', 'Cations', 'Crystallography, X-Ray', 'Histidine', 'Humans', 'Hydrophobic and Hydrophilic Interactions', 'Matrix Metalloproteinase 1', 'Molecular Dynamics Simulation', 'Water', 'Zinc'] | 28,161,785 | [['G02.111.570.120'], ['D01.248.497.300'], ['E05.196.309.742.225'], ['D12.125.072.329', 'D12.125.142.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.409'], ['D08.811.277.656.300.480.205.351', 'D08.811.277.656.300.480.525.700.100', 'D08.811.277.656.675.374.205.351', 'D08.811.277.656.675.374.525.700.100', '... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
GTV differentially impacts locoregional control of non-small cell lung cancer (NSCLC) after different fractionation schedules: subgroup analysis of the prospective randomized CHARTWEL trial. | PURPOSE: To evaluate the impact of fractionation schedule on the size of the gross tumour volume (GTV) effect on tumour control after radiotherapy of NSCLC.MATERIAL AND METHODS: A subgroup analysis on 163 patients treated in a randomized phase III trial of CHARTWEL (continuous hyperfractionated accelerated radiotherapy... | ['Aged', 'Aged, 80 and over', 'Carcinoma, Non-Small-Cell Lung', 'Dose Fractionation, Radiation', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Prospective Studies', 'Tumor Burden'] | 23,333,018 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['E02.815.639.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['E05.318.372.500.750.625', 'N05.715.360... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Competitive reverse transcriptase-polymerase chain reaction shows that dietary zinc supplementation in humans increases monocyte metallothionein mRNA levels. | Zinc status is difficult to evaluate in humans. Metallothionein gene expression is transcriptionally regulated by dietary zinc and thus could serve as an assessment parameter based on zinc-dependent function. We used semiquantitative reverse transcriptase-polymerase chain reaction (RT-PCR) to establish that MT mRNA is ... | ['Adult', 'Analysis of Variance', 'Base Sequence', 'Blotting, Northern', 'Cell Separation', 'Cells, Cultured', 'DNA, Complementary', 'Electrophoresis, Polyacrylamide Gel', 'Flow Cytometry', 'Food, Fortified', 'Gene Expression Regulation', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Leukemia, Myeloid', 'Male', ... | 9,164,988 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['A11.251'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 |
Clinical and histologic evaluation of a new injectable implant: hydrophilic polyacrylamide gel. | Hydrophilic polyacrylamide gel is a new, jellylike transparent implant that consists of 95% water and 5% polyacrylamide, and it has been applied in many countries for many years as a sort of injectable implant. However, there are no data regarding human tissue reaction to hydrophilic polyacrylamide gel to date. Thirty-... | ['Acrylic Resins', 'Adult', 'Chi-Square Distribution', 'Female', 'Foreign-Body Reaction', 'Humans', 'Male', 'Mammaplasty', 'Middle Aged', 'Prostheses and Implants', 'Reconstructive Surgical Procedures'] | 15,480,015 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['M01.060.116'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['C23.550.470.251', 'C26.392.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.218.565', 'E04.680.500'], ['M01.060.11... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Angiopoietins promote ovarian cancer progression by establishing a procancer microenvironment. | Despite decades of research, the survival rate of ovarian cancer patients is largely unchanged. Current chemotherapeutic drugs are effective only transiently because patients with advanced disease eventually develop resistance. Thus, there is a pressing need for identifying novel therapeutic targets in ovarian cancer. ... | ['Angiopoietins', 'Animals', 'Blotting, Western', 'Cell Line, Tumor', 'Cell Proliferation', 'Cystadenocarcinoma, Serous', 'Disease Progression', 'Female', 'Fluorescent Antibody Technique', 'Heterografts', 'Humans', 'Immunohistochemistry', 'Mice', 'Neoplasm Invasiveness', 'Neovascularization, Pathologic', 'Ovarian Neopl... | 25,043,619 | [['D12.644.276.100.100', 'D12.776.467.100.100', 'D23.529.100.100'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.557.470.200.025.480.240', 'C04.557.470.590.480.240']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Early environmental regulation of glucocorticoid feedback sensitivity in young adult monkeys. | Variations in maternal care induce in neonatal rodents life-long changes in glucocorticoid feedback regulation of the hypothalamic-pituitary-adrenal axis. This aspect of plasticity in neuroendocrine development has not been established in primates. We assessed, in young adult squirrel monkeys, postnatal rearing effects... | ['Adaptation, Physiological', 'Adrenocorticotropic Hormone', 'Animals', 'Corticotropin-Releasing Hormone', 'Environment', 'Feedback', 'Female', 'Glucocorticoids', 'Hydrocortisone', 'Hypothalamo-Hypophyseal System', 'Longitudinal Studies', 'Male', 'Maternal Behavior', 'Maternal Deprivation', 'Saimiri', 'Sex Factors', 'S... | 10,929,083 | [['G07.025', 'G16.012.500'], ['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['B01.050'], ['D06.472.699.327.740.140', 'D12.644.400.400.740.140', 'D12.644.548.365.740.14... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
[Reactions of N-quaternary 1-phenyl-3,4-dihydroisoquinolinium compounds with nucleophiles - products and their isomerism - part 1]. | Variously substituted 1-phenyl-3,4-dihydroisoquinolinium compounds were prepared, in order to study their reactions with hydroxide ions concerning ring-chain isomerism of their products. Thereby was observed a dependence on the electrophilic properties of C-1 for forming the pseudo-bases and a ring opening tendency to ... | ['Dimethyl Sulfoxide', 'Electrochemistry', 'Hydrogen', 'Indicators and Reagents', 'Isomerism', 'Isoquinolines', 'Magnetic Resonance Spectroscopy', 'Nitrogen'] | 12,688,246 | [['D02.886.640.150'], ['H01.181.529.307'], ['D01.268.406', 'D01.362.340'], ['D27.720.470.410'], ['G02.111.570.685', 'G02.607.445'], ['D03.633.100.531'], ['E05.196.867.519'], ['D01.268.604', 'D01.362.625']] | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Enhanced oxygen availability improves liver-specific functions of the AMC bioartificial liver. | Long-term culturing of primary porcine hepatocytes (PPH) inside the Academic Medical Center (AMC)-bioartificial liver is characterized by increased anaerobic glycolysis. Recommendations to increase oxygen availability were proposed in a previous numerical study and were experimentally evaluated in this study. Original ... | ['Animals', 'Bioreactors', 'Cells, Immobilized', 'Female', 'Hepatocytes', 'Humans', 'Liver', 'Liver Function Tests', 'Liver, Artificial', 'Oxygen', 'Oxygenators, Membrane', 'Sus scrofa'] | 18,005,273 | [['B01.050'], ['E07.115', 'J01.897.120.115'], ['A11.270'], ['A11.436.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['E01.370.372.460'], ['E07.858.082.620'], ['D01.268.185.550', 'D01.362.670'], ['E07.652.582'], ['B01.050.150.900.649.313.500.880.399']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Nucleic acid helix structure determination from NMR proton chemical shifts. | We present a method for de novo derivation of the three-dimensional helix structure of nucleic acids using non-exchangeable proton chemical shifts as sole source of experimental restraints. The method is called chemical shift de novo structure derivation protocol employing singular value decomposition (CHEOPS) and uses... | ['Nuclear Magnetic Resonance, Biomolecular', 'Nucleic Acid Conformation', 'Nucleic Acids', 'Protons', 'RNA'] | 23,564,038 | [['E05.196.867.519.550'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.444'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.660.500'], ['D13.444.735']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Gastrointestinal stromal tumor (GIST): a rare case of severe gastric haemorrhage]. | INTRODUCTION: A rare case of gastrointestinal stromal tumor (GIST) provoking a severe gastric bleeding is reported. Case report and results. The Authors report on the case of a 53-year-old male patient who presented with hematemesis, melena and severe acute anemia (Hb: 6 g/dl). EGDS disclosed a protruding lesion centra... | ['Anastomosis, Roux-en-Y', 'Diagnosis, Differential', 'Disease-Free Survival', 'Gastrectomy', 'Gastrointestinal Hemorrhage', 'Gastrointestinal Neoplasms', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Prognosis', 'Risk Factors', 'Stromal Cells'] | 15,283,391 | [['E04.035.070', 'E04.210.070'], ['E01.171'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['E04.210.419'], ['C06.405.227', 'C23.550.414.788'], ['C04.588.274.476', 'C06.301.371', 'C06.405.249'], ['B01.050.150.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Direct pulp capping with mineral trioxide aggregate: an observational study. | BACKGROUND: Pulp capping in carious teeth has been considered unpredictable and therefore contraindicated. A recently developed material, mineral trioxide aggregate (MTA), resists bacterial leakage and may provide protection for the pulp, allowing repair and continued pulp vitality in teeth when used in combination wit... | ['Adolescent', 'Adult', 'Aluminum Compounds', 'Calcium Compounds', 'Child', 'Dental Caries', 'Dental Pulp Capping', 'Dental Restoration, Permanent', 'Dentin, Secondary', 'Drug Combinations', 'Hemostatics', 'Humans', 'Kaplan-Meier Estimate', 'Life Tables', 'Middle Aged', 'Oxides', 'Pulpitis', 'Silicate Cement', 'Silicat... | 18,310,735 | [['M01.060.057'], ['M01.060.116'], ['D01.056'], ['D01.146'], ['M01.060.406'], ['C07.793.720.210'], ['E06.397.370'], ['E06.323.428', 'E06.780.346.737', 'E07.695.190.190'], ['A14.549.167.900.280.280', 'C07.793.237.378'], ['D26.310'], ['D27.505.954.502.270.463'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Genome-wide association study for intramuscular fat deposition and composition in Nellore cattle. | BACKGROUND: Meat from Bos taurus and Bos indicus breeds are an important source of nutrients for humans and intramuscular fat (IMF) influences its flavor, nutritional value and impacts human health. Human consumption of fat that contains high levels of monounsaturated fatty acids (MUFA) can reduce the concentration of ... | ['Adiposity', 'Animals', 'Bayes Theorem', 'Breeding', 'Cattle', 'Fatty Acids', 'Genetic Association Studies', 'Male', 'Meat', 'Muscle, Skeletal', 'Polymorphism, Single Nucleotide', 'Quantitative Trait Loci'] | 24,666,668 | [['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['B01.050'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['E05.820.150', 'G05.090'], ['B01.050.150.900.649.313.500.380.271'], ['D10.251'], ['E05.393.385'], ['G07.203.300.600', 'J02.500.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Allocentric information is used for memory-guided reaching in depth: A virtual reality study. | Previous research has demonstrated that humans use allocentric information when reaching to remembered visual targets, but most of the studies are limited to 2D space. Here, we study allocentric coding of memorized reach targets in 3D virtual reality. In particular, we investigated the use of allocentric information fo... | ['Adult', 'Analysis of Variance', 'Computer Simulation', 'Convergence, Ocular', 'Cues', 'Depth Perception', 'Female', 'Humans', 'Male', 'Memory', 'Mental Recall', 'Movement', 'Photic Stimulation', 'Psychomotor Performance', 'Space Perception', 'Vision Disparity', 'Young Adult'] | 27,789,230 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['L01.224.160'], ['G14.350.217'], ['F02.463.425.234'], ['F02.463.593.200', 'F02.463.593.778.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540'], ['F02.463.425.540.641'], ['G07.568', 'G11.427.410'], ['E05.723.729... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The evolution of autosomal suppressors of sex-ratio drive in Drosophila simulans. | Sex-ratio drive, which results in males siring female-biased progeny, has been reported in several Drosophila species, including D. simulans. It is caused by X-linked drivers that prevent the production of Y-bearing sperm. In natural populations of D. simulans, the drivers are usually cryptic, because their spread has ... | ['Africa, Eastern', 'Animals', 'Drosophila', 'Evolution, Molecular', 'Meiosis', 'Polymorphism, Genetic', 'Sex Ratio', 'Suppression, Genetic', 'X Chromosome'] | 12,656,572 | [['Z01.058.290.120'], ['B01.050'], ['B01.050.500.131.617.720.500.500.750.310.250'], ['G05.045.250', 'G16.075.250'], ['G04.144.220.220.687', 'G05.113.220.687'], ['G05.365.795'], ['G05.815', 'I01.240.800.815', 'N01.224.803.815', 'N06.850.505.400.850.815'], ['G05.365.590.835', 'G05.558.835'], ['A11.284.187.865.982', 'G05.... | ['Geographicals [Z]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Hsa-miR-497 as a new regulator in TGFâ signaling pathway and cardiac differentiation process. | Cardiosphere-derived cells (CDCs) contain cardiac stem cell subpopulations and are introduced as useful source for cardiac differentiation and therapy. Furthermore, research has highlighted miRNAs important role in various biological processes and cardiogenesis. Here, we intended to investigate the effect of hsa-miR-49... | ['Cell Differentiation', 'Cells, Cultured', 'HEK293 Cells', 'Humans', 'MicroRNAs', 'Myocytes, Cardiac', 'Receptors, Transforming Growth Factor beta', 'Signal Transduction', 'Stem Cells', 'Transforming Growth Factor beta1'] | 29,969,696 | [['G04.152'], ['A11.251'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['A07.541.704.570', 'A10.690.552.750.570', 'A11.620.500'], ['D12.776.543.750.705.852.720', 'D12.776.543.750.750.400.820'], ['G02.111.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Improved Comparative Signature Diagrams to Evaluate Similarity of Storage Stability Profiles of Different IgG1 mAbs. | For therapeutic protein analytical studies related to evaluating lot-to-lot variability, different processes and/or formulations, or biosimilars, there is growing interest in applying novel data visualization tools for fingerprint analysis to identify statistically significant differences between 2 samples. Comparative... | ['Antibodies, Monoclonal', 'Biosimilar Pharmaceuticals', 'Chemistry, Pharmaceutical', 'Chromatography, Gel', 'Drug Stability', 'Drug Storage', 'Immunoglobulin G', 'Protein Stability'] | 26,886,311 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D20.215.261'], ['H01.158.703.007', 'H01.181.466'], ['E05.196.181.400.250'], ['E05.916.330'], ['E05.916.350'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['G02... | ['Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A facile and green method for synthesis of reduced graphene oxide/Ag hybrids as efficient surface enhanced Raman scattering platforms. | Reduced graphene oxide/Ag nanoparticles hybrids (rGO/AgNPs) were fabricated via a green and facile hydrothermal method. The as-synthesized materials were characterized in detail using various spectroscopic and microscopic techniques. Under a suitable dosage of silver ions, well-dispersed AgNPs on the reduced graphene o... | ['Graphite', 'Green Chemistry Technology', 'Metal Nanoparticles', 'Silver', 'Spectrum Analysis, Raman'] | 25,262,484 | [['D01.268.150.300', 'D01.578.300'], ['J01.897.360'], ['J01.637.512.600.500'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.544.812'], ['E05.196.822.860', 'E05.196.867.890']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Rib cage and diaphragm-abdomen compliance in humans: effects of age and posture. | The influence of age and posture on compliance of the rib cage (Crc) and diaphragm-abdomen (Cab) compartments of the chest wall was studied in 61 healthy adults (33 men, 28 women) aged 24-75 yr. Chest wall compliance (Cw) was measured by the weighted spirometer technique; Crc and Cab were derived from the slope of the ... | ['Abdomen', 'Adult', 'Age Factors', 'Aged', 'Diaphragm', 'Female', 'Humans', 'Lung Volume Measurements', 'Male', 'Middle Aged', 'Muscle Relaxation', 'Posture', 'Pressure', 'Respiration', 'Ribs', 'Thorax'] | 4,077,793 | [['A01.923.047'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['A02.633.567.900.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.386.700.485'], ['M01.060.116.630'], ['G11.427.494.554'], ['G11.427.695'], ['G01.374.715'], ['G09.772.705'], ['A02.835.232.570.500'], ['A01.9... | ['Anatomy [A]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Thermostability of the rabies virion. Optical density measurement technique applications. | The thermal degradation of rabies virus was determined by the variation in optical density at 260 nm during temperature rise. This variation, linked to denaturation of RNA, was seen by an irreversible sigmoidal curve. Analysis of the state of the virion by ultracentrifugation did not show any alteration in sedimentatio... | ['Animals', 'Cricetinae', 'Edetic Acid', 'Magnesium', 'Nucleic Acid Denaturation', 'RNA, Viral', 'Rabies virus', 'Spectrophotometry, Ultraviolet', 'Temperature', 'Viral Proteins', 'Virion'] | 6,813,020 | [['B01.050'], ['B01.050.150.900.649.313.992.635.075.250'], ['D02.092.782.258.368.250', 'D02.241.081.018.253'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['E05.393.640', 'G02.111.603', 'G05.627'], ['D13.444.735.828'], ['B04.820.480.937.750.500.700'], ['E05.196.712.726.802', 'E05.196.867.826.802'], ['G01... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Unusual late presentation of asymptomatic diaphragmatic hernia following ventricular assist device explantation. | The role of left ventricular assist device (LVAD) in treatment options of congestive heart failure is becoming more important and the widespread application is imminent. There are, however, some serious complications associated with LVAD, which make patient management more challenging. We report a rare surgical case of... | ['Diagnosis, Differential', 'Elective Surgical Procedures', 'Follow-Up Studies', 'Heart Failure', 'Heart Transplantation', 'Heart-Assist Devices', 'Hernia, Diaphragmatic', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Radiography, Thoracic', 'Thoracotomy'] | 18,042,565 | [['E01.171'], ['E04.249'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C14.280.434'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['C23.300.707.960.500'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inhibition of phosphatidylinositol 3-kinase delays tumor progression and blocks metastatic spread in a mouse model of thyroid cancer. | Aberrant activation of the phosphatidylinositol 3-kinase (PI3K)-AKT/protein kinase B-signaling pathway has been associated with multiple human cancers, including thyroid cancer. Recently, we showed that, similar to human thyroid cancer, the PI3K-AKT pathway is overactivated in both the thyroid and metastatic lesions of... | ['Adenocarcinoma, Follicular', 'Animals', 'Apoptosis', 'Caspase 3', 'Cell Movement', 'Cell Proliferation', 'Chromones', 'Cyclin D1', 'Cyclin-Dependent Kinase Inhibitor p27', 'Lung Neoplasms', 'Matrix Metalloproteinase 2', 'Mice', 'Mice, Mutant Strains', 'Morpholines', 'Neoplasm Invasiveness', 'Phosphoinositide-3 Kinase... | 17,660,507 | [['C04.557.470.200.025.060'], ['B01.050'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['G04.198', 'G07.568.500.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D03.383.663.283.266', 'D03.633.100.150.2... | ['Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Occurrence and distribution of unsubstituted B-ring flavanones in Eucalyptus foliage. | A group of plant specialised metabolites (PSMs) collectively known as unsubstituted B-ring flavanones (UBFs) have previously been found in the foliage of some species from the genus Eucalyptus L'H?r. (Myrtaceae), specifically from the subgenus Eucalyptus (monocalypts). Captive feeding studies using artificial diets sug... | ['Eucalyptus', 'Flavanones', 'Hydrolysis'] | 30,682,682 | [['B01.650.940.800.575.912.250.773.366'], ['D03.383.663.283.266.450.252', 'D03.633.100.150.266.450.252'], ['G02.380']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Direct interaction of CaVâ with actin up-regulates L-type calcium currents in HL-1 cardiomyocytes. | Expression of the â-subunit (CaVâ) is required for normal function of cardiac L-type calcium channels, and its up-regulation is associated with heart failure. CaVâ binds to the á1 pore-forming subunit of L-type channels and augments calcium current density by facilitating channel opening and increasing the number of ch... | ['Actin Cytoskeleton', 'Actins', 'Animals', 'Calcium Channels, L-Type', 'Calcium Signaling', 'Cell Line', 'Cell Membrane', 'Cytochalasin D', 'Mice', 'Models, Biological', 'Myocytes, Cardiac', 'Nucleic Acid Synthesis Inhibitors', 'Protein Transport', 'Rats', 'Up-Regulation', 'src Homology Domains'] | 25,533,460 | [['A11.284.430.214.190.750.050'], ['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['D12.776.157.530.400.150.400', 'D12.776.543.550.450.150.400', 'D12.776.543.585.400.150.400'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['A11.251.210'], ['A11.284.149'], ['D03.633.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Versatility of the endoventricular patch technique in repair of postinfarction left ventricular rupture. | Surgical ventricular restoration by the endoventricular patch technique (Dor procedure) is a surgical option designed to restore left ventricular shape and volume in patients with ischaemic heart disease and heart failure. Surgical ventricular restoration includes complete revascularisation, left ventricular reconstruc... | ['Aged', 'Cardiac Surgical Procedures', 'Heart Rupture, Post-Infarction', 'Heart Septal Defects, Ventricular', 'Heart Ventricles', 'Humans', 'Male'] | 18,465,038 | [['M01.060.116.100'], ['E04.100.376', 'E04.928.220'], ['C14.280.470.475'], ['C14.240.400.560.540', 'C14.280.400.560.540', 'C16.131.240.400.560.540'], ['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Integration of leprosy elimination into primary health care in orissa, India. | BACKGROUND: Leprosy was eliminated as a public health problem (<1 case per 10,000) in India by December 2005. With this target in sight the need for a separate vertical programme was diminished. The second phase of the National Leprosy Eradication Programme was therefore initiated: decentralisation of the vertical prog... | ['Awareness', 'Counseling', 'Delivery of Health Care, Integrated', 'Drug Therapy, Combination', 'Health Education', 'Humans', 'India', 'Leprosy', 'Patient Compliance', 'Primary Health Care', 'Quality of Health Care', 'Registries', 'Reproducibility of Results'] | 20,020,051 | [['F02.463.188.150'], ['F02.784.176', 'F04.408.413', 'N02.421.143.303', 'N02.421.461.363'], ['N04.590.374.142', 'N05.300.262'], ['E02.319.310'], ['I02.233.332', 'N02.421.726.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['C01.150.252.410.040.552.475.371'], ['F01.100.150.750.500.600', 'F01... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Ultrasonography Findings of Urinary Tract Infection After Kidney Transplant: A Case Report. | Urinary tract infection is the most common complication after kidney transplant and often is associated with graft loss and mortality. Ultrasonography is the most widely applied imaging modality for diagnosis of complications after kidney transplant. Here, we report a case of a 52-year-old male patient who underwent re... | ['Abscess', 'Anti-Bacterial Agents', 'Drainage', 'Humans', 'Kidney', 'Kidney Transplantation', 'Klebsiella Infections', 'Klebsiella pneumoniae', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Treatment Outcome', 'Ultrasonography, Doppler', 'Urinary Tract Infections'] | 29,528,007 | [['C01.830.025', 'C23.550.470.756.100'], ['D27.505.954.122.085'], ['E02.309', 'E04.237'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['E02.870.500', 'E04.936.450.485', 'E04.950.774.400'], ['C01.150.252.400.310.503'], ['B03.440.450.425.425.600', 'B03.660.250.150.400.590'], ['M01.060.116.630'], ['E... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[The importance of larynx electromyography for the differential diagnosis of vocal cord fixation]. | Fourteen patients have been studied, with precedents of endotracheal intubation, suffering dysphonia and fixation of one vocal cord (13 cases) or both (1 case). The lack of neutrogen signs was confirmed through conventional electromyography, and objectivity because the clinical findings pointing to a direct traumatism ... | ['Adult', 'Aged', 'Diagnosis, Differential', 'Electromyography', 'Female', 'Humans', 'Laryngoscopy', 'Male', 'Middle Aged', 'Vocal Cord Paralysis', 'Vocal Cords'] | 12,053,509 | [['M01.060.116'], ['M01.060.116.100'], ['E01.171'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.386.460', 'E01.370.388.250.525', 'E04.502.250.525', 'E04.580.373'], ['M01.060.116.630'], ['C08.360.931', 'C09.400.931', 'C10.292.887.800', 'C10.597.622.943', 'C23.888.59... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Interferon-beta, but not tumor necrosis factor-alpha, production in response to poly I:C is maintained despite exhaustive exercise in mice. | It remains unclear whether immune response to viral infection is inhibited by severe exercise. We determined whether exhaustive exercise inhibits interferon (IFN)-â and tumor necrosis factor (TNF)-á production after injection of synthetic double-stranded (ds) RNAs, a polyriboinosinic polyribocytidylic acid (poly I:C), ... | ['Animals', 'Dopamine', 'Epinephrine', 'Interferon-beta', 'Macrophages', 'Male', 'Mice', 'Mice, Inbred C3H', 'Norepinephrine', 'Physical Exertion', 'Poly I-C', 'Stress, Physiological', 'Tumor Necrosis Factor-alpha'] | 21,968,540 | [['B01.050'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D02.033.100.291.310', 'D02.092.063.291.310', 'D02.092.211.215.454', 'D02.092.311.461', 'D02.455.426.559.389.657.166.175.461'], ['D12.644.276.374.440.890.275', 'D12.776.467.374.440.890.275', 'D23.529.374.440.890.275'], ['A... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sexually dimorphic gene expression in mouse brain precedes gonadal differentiation. | The classic view of brain sexual differentiation and behavior is that gonadal steroid hormones act directly to promote sex differences in neural and behavioral development. In particular, the actions of testosterone and its metabolites induce a masculine pattern of brain development, while inhibiting feminine neural an... | ['Animals', 'Brain', 'Female', 'Fetus', 'Gene Expression Regulation, Developmental', 'Gonadal Steroid Hormones', 'Gonads', 'Male', 'Mice', 'Nerve Tissue Proteins', 'Oligonucleotide Array Sequence Analysis', 'RNA, Messenger', 'Sex Characteristics', 'Sex Differentiation'] | 14,559,357 | [['B01.050'], ['A08.186.211'], ['A16.378'], ['G05.308.310'], ['D06.472.334.851'], ['A05.360.576', 'A06.300.312'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.776.631'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['D13.444.735.544'], ['G08.686.815'], ['G07.345.500.325.377.843', 'G07... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Origin of the adenohypophysis and of the olfactory system in toads: demonstration by chimera method]. | Localisation of the primordium of the olfactory system and its topographical relationships with the primordium of the hypothalamic-hypophyseal system were determined on the embryos of the toad Bufo japonicus by generating chimeric embryos. Different parts of the neural ridge and the neural plate were taken up from norm... | ['Animals', 'Bufonidae', 'Olfactory Pathways', 'Pituitary Gland, Anterior', 'Transplantation Chimera'] | 8,869,240 | [['B01.050'], ['B01.050.150.900.090.180.210'], ['A08.186.211.180.699', 'A08.612.220.640'], ['A06.300.747.500', 'A06.688.357.750.500', 'A08.186.211.180.497.352.435.500.500', 'A08.186.211.200.317.357.352.435.500.500', 'A08.713.357.750.500'], ['B05.200.750']] | ['Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Economic evaluation of donepezil in moderate to severe Alzheimer disease. | OBJECTIVE: To investigate the costs to society of Alzheimer disease (AD) care in a multinational, randomized, placebo-controlled trial of donepezil in patients with moderate to severe AD.METHODS: A total of 290 patients with AD (screening standardized Mini-Mental State Examination score 5 to 17) were randomized to rece... | ['Activities of Daily Living', 'Aged', 'Alzheimer Disease', 'Ambulatory Care', 'Australia', 'Canada', 'Caregivers', 'Cholinesterase Inhibitors', 'Cost of Illness', 'Cost-Benefit Analysis', 'Counseling', 'Donepezil', 'Drug Costs', 'Female', 'France', 'Health Resources', 'Home Care Services', 'Home Nursing', 'Hospitaliza... | 15,326,236 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E02.760.106', 'N02.421.585.106'], ['Z01.639.100', 'Z01.678.100.373'], ['Z01.107.567.176'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['D27.505.519.389.275... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Safety assessment of standardised methanol extract of Cinnamomum burmannii. | The present study aims to evaluate the safety of methanol extract of Cinnamomum burmannii (MECB) by acute 14-day (single dose) and sub-chronic 28-day (repeated doses) oral administration to Sprague-Dawley rats. Our results showed that no toxicity was found in either acute or sub-chronic toxicity studies. MECB (containi... | ['Administration, Oral', 'Animals', 'Chromatography, High Pressure Liquid', 'Chromatography, Thin Layer', 'Cinnamomum', 'Dose-Response Relationship, Drug', 'Drugs, Chinese Herbal', 'Female', 'Male', 'Methanol', 'No-Observed-Adverse-Effect Level', 'Organ Size', 'Plant Extracts', 'Rats', 'Rats, Sprague-Dawley', 'Safety',... | 23,827,665 | [['E02.319.267.100'], ['B01.050'], ['E05.196.181.400.300'], ['E05.196.181.400.537'], ['B01.650.940.800.575.912.250.595.400.149'], ['G07.690.773.875', 'G07.690.936.500'], ['D20.215.784.500.350', 'D26.335'], ['D02.033.623'], ['E05.940.600', 'G07.690.936.750'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Multipoint-emitting optical fibers for spatially addressable in vivo optogenetics. | Optical stimulation and silencing of neural activity is a powerful technique for elucidating the structure and function of neural circuitry. In most in vivo optogenetic experiments, light is delivered into the brain through a single optical fiber. However, this approach limits illumination to a fixed volume of the brai... | ['Animals', 'Brain', 'Electrodes, Implanted', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Microelectrodes', 'Nerve Net', 'Optical Fibers', 'Optogenetics', 'Photic Stimulation'] | 24,881,834 | [['B01.050'], ['A08.186.211'], ['E07.305.250.319', 'E07.695.202'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['E07.305.250.500'], ['A08.511'], ['E07.632.750'], [... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Risk factors for postcraniotomy surgical site infection after 1,3-bis (2-chloroethyl)-1-nitrosourea (Gliadel) wafer placement. | Gliadel wafers (1,3-bis [2-chloroethyl]-1-nitrosourea; Guilford Pharmaceuticals) are approved for the treatment of malignant gliomas; however, the incidence of and risk factors associated with infection with respect to this new technology are unknown. We identified 32 patients who received Gliadel wafers from December ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Cohort Studies', 'Drug Implants', 'Glioma', 'Humans', 'Middle Aged', 'Multivariate Analysis', 'Postoperative Complications', 'Risk Factors'] | 12,627,360 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D26.255.210.315'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Arterial blood acid-base regulation during exercise in rats. | For the first time in the rat, we described the effects of exercise on arterial acid-base status and examined the role of chemical stimuli as determinants of the hyperventilatory response in this species. O2 consumption (VO2), CO2 production (VCO2), arterial blood gases, arterial lactate concentration ([LA-]a), and rec... | ['Acid-Base Equilibrium', 'Animals', 'Arteries', 'Blood', 'Body Temperature', 'Male', 'Physical Exertion', 'Rats', 'Rats, Inbred Strains', 'Respiration'] | 6,469,809 | [['G02.111.007', 'G02.300.176', 'G03.030', 'G07.410.110', 'G09.188.050'], ['B01.050'], ['A07.015.114'], ['A12.207.152', 'A15.145'], ['E01.370.600.875.374', 'G07.110'], ['G11.427.683'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['G09.772.705'... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cell-mediated immunity to herpes simplex virus: specificity of cytotoxic T cells. | This communication deals with the question of which of the viral antigens constitutes the targets for cytotoxic T lymphocytes (CTL) generated against herpes simplex virus type 1 (HSV-1). The approach used was, first, to compare cytotoxicity of CTL against target cells infected with virus in the presence of tunicamycin ... | ['Animals', 'Antigens, Viral', 'Cytotoxicity, Immunologic', 'Deoxyglucose', 'Glycoproteins', 'H-2 Antigens', 'Herpes Simplex', 'Immunity, Cellular', 'L Cells', 'Mice', 'T-Lymphocytes', 'Tunicamycin', 'Viral Proteins'] | 6,969,228 | [['B01.050'], ['D23.050.327'], ['G12.287'], ['D09.254.229'], ['D09.400.430', 'D12.776.395'], ['D23.050.301.500.100.350', 'D23.050.301.500.400.199', 'D23.050.705.552.100.350', 'D23.050.705.552.410.199'], ['C01.925.256.466.382', 'C01.925.825.320', 'C17.800.838.790.320'], ['G12.450.050.400'], ['A11.251.210.505', 'A11.329.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of quercetin on the apoptosis of the human gastric carcinoma cells. | Quercetin, a natural constituent abundantly present in grapes, red wine, and other food products, is known to possess potent antiproliferative effects against various malignant cells. The present study aims to investigate the effect of quercetin on the apoptosis and morphology of gastric carcinoma BGC-823 cells, as wel... | ['Apoptosis', 'Carcinoma', 'Caspase 3', 'Cell Cycle', 'Cell Line, Tumor', 'Humans', 'Proto-Oncogene Proteins c-bcl-2', 'Quercetin', 'Stomach Neoplasms', 'bcl-2-Associated X Protein'] | 22,222,411 | [['G04.146.954.035'], ['C04.557.470.200'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.360.075.718', 'D12.776.... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparison of two endometrial sampling devices. Cotton-tipped swab and double-lumen catheter with a brush. | The potential for bacterial contamination during transvaginal recovery of endometrial samples in patients with postpartum endomyometritis spawned an investigation into various protective measures and techniques. The confirmation and determination of the extent of contamination was attempted in 120 postpartum women with... | ['Bacterial Infections', 'Endometritis', 'Endometrium', 'Female', 'Humans', 'Pregnancy', 'Prospective Studies', 'Puerperal Infection', 'Specimen Handling'] | 2,585,387 | [['C01.150.252'], ['C13.351.500.056.750.249', 'C13.351.500.852.299'], ['A05.360.319.679.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C01.674.715', 'C13.703.700.715', 'C13.703.844.757'], ['E01.370... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The open section effect in a long bone with a longitudinal defect - a theoretical modeling study. | A longitudinal defect dramatically alters the stress distribution within a long bone. The altered stress distribution can influence the structural properties of the bone and the stimulus for repair and remodeling of the defect and the surrounding bone. For applied torsion, the defect interrupts the normal shear flow ar... | ['Biomechanical Phenomena', 'Bone and Bones', 'Femur', 'Humans', 'Models, Biological', 'Stress, Mechanical'] | 10,940,413 | [['G01.154.090', 'G01.374.089'], ['A02.835.232', 'A10.165.265'], ['A02.835.232.043.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395'], ['G01.374.835']] | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Analysis and identification of Semen Glycines Nigrae and Semen Pharbitidis by infrared spectroscopy]. | Semen Glycines Nigrae and Semen Pharbitidis containing a large amount of fats and proteins are commonly used in Chinese herbal medicine. Tri-step infrared spectroscopy was applied to fast analyze and identify the two samples. In the conventional infrared spectroscopy, the samples both have obvious characteristic absorp... | ['Convolvulaceae', 'Seeds', 'Soybeans', 'Spectrophotometry, Infrared'] | 25,532,339 | [['B01.650.940.800.575.912.250.238'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'], ['B01.650.940.800.575.912.250.401.750'], ['E05.196.712.726.676', 'E05.196.867.826.676']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Dressing changes by specialized personnel reduce infection rates in patients receiving central venous parenteral nutrition. | In 60 pediatric patients, 75 central venous catheters representing 1866 patient days were placed to provide parenteral nutrition. During the 21-month study period, surgical residents were responsible for dressing changes during the first 16 months and a specially trained nurse was responsible during the final 5 months.... | ['Bacterial Infections', 'Bandages', 'Catheters, Indwelling', 'Child', 'Humans', 'Internship and Residency', 'Nursing Care', 'Parenteral Nutrition'] | 3,083,137 | [['C01.150.252'], ['E07.101'], ['E07.132.500'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.358.337.350.500', 'I02.358.399.350.750'], ['E02.760.611', 'N02.421.533'], ['E02.421.505', 'E02.642.500.505']] | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Bedtime administration of metformin may reduce insulin requirements]. | The administration of metformin, as glucophage retard, at bedtime instead of supper time may improve diabetes control by reducing morning hyperglycemia. This modification of glucophage treatment was tried in 3 groups of diabetic patients: I. those with secondary failure of routine treatment with sulfonylurea (SU) and g... | ['Blood Glucose', 'Diabetes Mellitus', 'Diabetes Mellitus, Type 2', 'Drug Therapy, Combination', 'Humans', 'Insulin', 'Metformin', 'Time Factors'] | 2,258,095 | [['D09.947.875.359.448.500'], ['C18.452.394.750', 'C19.246'], ['C18.452.394.750.149', 'C19.246.300'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D02.078.370.141.450'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Does pornography-blocking software block access to health information on the Internet? | CONTEXT: The Internet has become an important tool for finding health information, especially among adolescents. Many computers have software designed to block access to Internet pornography. Because pornography-blocking software cannot perfectly discriminate between pornographic and nonpornographic Web sites, such pro... | ['Access to Information', 'Adolescent', 'Computer Simulation', 'Erotica', 'Health Education', 'Humans', 'Internet', 'Medical Informatics', 'Security Measures', 'Sexuality', 'Software'] | 12,472,332 | [['I01.880.604.473.352.500.030', 'L01.143.024', 'L01.737.030'], ['M01.060.057'], ['L01.224.160'], ['K01.517.414', 'L01.178.682.441'], ['I02.233.332', 'N02.421.726.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['L01.313.500'], ['N04.452.910'], ['F01.145.802.975', 'G08.686.867'], ['L01.... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Named Groups [M]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
Experimental infection of inbred guinea pigs with Treponema pallidum: development of lesions and formation of antibodies. | Inbred strain 2 and strain 13 guinea pigs were infected intradermally in the hind legs with different numbers of the virulent Nichols strain of Treponema pallidum. About 91% of the animals developed clearly visible lesions after being injected with 5 X 10(6) to 10 X 10(6) treponemes. T pallidum organisms could be isola... | ['Animals', 'Antibodies, Bacterial', 'Cardiolipins', 'Fluorescent Antibody Technique', 'Guinea Pigs', 'Hemagglutination Tests', 'Syphilis', 'Time Factors', 'Treponema pallidum'] | 3,884,485 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D10.570.755.375.760.400.885.185', 'D23.050.550.480.330'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The cement-free modular revision prosthesis MRP-hip revision stem prosthesis in clinical follow-up]. | INTRODUCTION: We present prospective medium-term results of the modular revision prostheses "MRP-TITANIUM".MATERIAL AND METHODS: 45 patients (n = 48 prostheses) were evaluated. The mean follow-up was 4.7 years (min.-max.: 1.0-9.0 years). Pre- and postoperatively the Harris hip score (differentiated to Paprosky I-III) w... | ['Aged', 'Aged, 80 and over', 'Equipment Failure Analysis', 'Female', 'Follow-Up Studies', 'Hip Joint', 'Hip Prosthesis', 'Humans', 'Male', 'Radiography', 'Recovery of Function', 'Reoperation', 'Titanium', 'Treatment Outcome'] | 15,250,004 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.325.192'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A02.835.583.411'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700'], ['G16.757'], ['E04.690'], ['D01.268.557.800', 'D01.26... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chemoenzymatic synthesis of the 3-sulfated Lewisa pentasaccharide. | The sulfated pentasaccharide benzyl O-(3-O-sulfo-beta-D-galactopyranosyl)-(1-->3)-O-[(alpha-L-fucopyranosyl)-(1-->4)]-O-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)-(1-->3)-O-(beta-D-galactopyranosyl)-(1-->4)-O-beta-D-glucopyranoside sodium salt was synthesized using a chemo-enzymatic approach. Lacto-N-tetraose, obtaine... | ['Carbohydrate Sequence', 'Fucosyltransferases', 'Lewis Blood Group Antigens', 'Molecular Sequence Data', 'Oligosaccharides', 'Sulfuric Acid Esters'] | 16,274,756 | [['G02.111.570.160', 'L01.453.245.667.160'], ['D08.811.913.400.450.300'], ['D23.050.301.290.544', 'D23.050.705.230.544'], ['L01.453.245.667'], ['D09.698.629'], ['D02.886.645.655.850']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Home health and telemedicine: where are we today? | This chapter will review the current state-of-the-art of home health services in the telemedicine environment. Special attention will be paid to some of the studies that our telemedicine program has conducted in the past few years. The chapter will conclude with some recommendations and a look to the future. | ['Adult', 'Aged', 'Aged, 80 and over', 'Arizona', 'Cost-Benefit Analysis', 'Female', 'Home Care Services', 'Humans', 'Male', 'Middle Aged', 'Organizational Case Studies', 'Program Evaluation', 'Surveys and Questionnaires', 'Telemedicine', 'Telemetry'] | 15,747,971 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.107.567.875.760.100'], ['N03.219.151.125'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N03.349.380.710', 'N05.715.360.455'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['E05... | ['Named Groups [M]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Inhibitory effects of theophylline and procaterol on eosinophil function. | Eosinophils play a crucial role in bronchial asthma. As theophylline and procaterol (beta 2-agonist) are used for the treatment of bronchial asthma, the specific functions of eosinophils in the presence of granulocyte/macrophage colony-stimulating factor (GM-CSF) or platelet activating factor (PAF) were examined using ... | ['Asthma', 'Bronchodilator Agents', 'CD11 Antigens', 'CD18 Antigens', 'Cell Adhesion Molecules', 'Cell Degranulation', 'Eosinophils', 'Granulocyte-Macrophage Colony-Stimulating Factor', 'Humans', 'In Vitro Techniques', 'Platelet Activating Factor', 'Procaterol', 'Recombinant Proteins', 'Theophylline'] | 9,187,566 | [['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['D12.776.395.550.200.074', 'D12.776.543.550.200.093', 'D23.050.301.350.074'], ['D12.776.395.550.200.275.750', 'D12.776.543.550.200.275.750', 'D12.776.543.750.705.408.200.249', 'D12.776.543... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hepatitis C virus genotype distribution in China: predominance of closely related subtype 1b isolates and existence of new genotype 6 variants. | To determine hepatitis C virus (HCV) genotype distribution in China, a total of 148 HCV RNA positive serum samples were collected from nine geographic areas and subjected to RT-PCR followed by direct DNA sequencing and phylogenetic analysis of the core, E1, and NS5B regions. HCV was genotyped in 139 (93.9%) samples. Am... | ['China', 'DNA, Viral', 'Genetic Variation', 'Genotype', 'Hepacivirus', 'Hepatitis C', 'Humans', 'Molecular Sequence Data', 'Phylogeny', 'RNA, Viral', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sequence Analysis, DNA', 'Viral Proteins'] | 15,714,489 | [['Z01.252.474.164'], ['D13.444.308.568'], ['G05.365'], ['G05.380'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['D13.444.73... | ['Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
Use of full sterile barrier precautions during insertion of arterial catheters: a randomized trial. | To investigate whether institution of maximal sterile barrier precautions (SBPs) during arterial catheter (AC) insertion prevents catheter colonization, as is the case for central venous catheters (CVCs), a randomized study was conducted. Three hundred seventy-three patients in whom a radial or dorsalis pedis AC was go... | ['Catheterization, Central Venous', 'Catheterization, Peripheral', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prosthesis-Related Infections', 'Sterilization'] | 12,627,358 | [['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['E02.148.224', 'E04.100.814.529.937', 'E04.502.382.937', 'E05.157.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C01.685', 'C23.550.767.868'], ['N06.850.780.200.450.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chromium-51 ethylenediaminetetraacetate for estimation of globerular filtration rate. | Renal clearances of inulin and chromium-51 ethylenediaminetetraacetate were compared in sheep. In 41 clearance periods from five animals the mean clearance ratio of the chelate to inulin was 0.95 +/- 0.03 (S.D.). Part of the difference between the two sets of results may have been due to binding of the metal chelate by... | ['Animals', 'Chromium Isotopes', 'Edetic Acid', 'Glomerular Filtration Rate', 'In Vitro Techniques', 'Sheep'] | 4,956,507 | [['B01.050'], ['D01.268.556.175.500', 'D01.268.956.124.500', 'D01.496.212', 'D01.552.544.175.500'], ['D02.092.782.258.368.250', 'D02.241.081.018.253'], ['E01.370.390.400.300', 'G08.852.357'], ['E05.481'], ['B01.050.150.900.649.313.500.380.791']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Stillbirths and early neonatal mortality in rural Northern Ghana. | OBJECTIVE: To calculate perinatal mortality (stillbirth and early neonatal death: END) rates in the Upper East region of Ghana and characterize community-based stillbirths and END in terms of timing, cause of death, and maternal and infant risk factors.METHODS: Birth outcomes were obtained from the Navrongo Health and ... | ['Adolescent', 'Adult', 'Asphyxia Neonatorum', 'Birth Injuries', 'Cause of Death', 'Female', 'Gestational Age', 'Ghana', 'Humans', 'Infant Mortality', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Infant, Premature', 'Infections', 'Perinatal Mortality', 'Population Surveillance', 'Pregnancy', 'Pregnancy Complication... | 22,175,764 | [['M01.060.057'], ['M01.060.116'], ['C16.614.092'], ['C16.614.131', 'C26.141'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['G07.345.500.325.235.968', 'G08.686.320'], ['Z01.058.290.190.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.31... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Acetylsalicylic acid antagonizes the bleeding-induced changes in hemoglobin proportions in normal adult rats. | Normal adult Sprague-Dawley rats were made anemic by repeated phlebotomy. Ion-exchange chromatography of anemic blood showed newborn like hemoglobin proportions, involving the same six hemoglobin components as is found when newborn and adult blood are compared. However, acetylsalicylic acid intake during anemia failed ... | ['Animals', 'Aspirin', 'Dose-Response Relationship, Drug', 'Erythropoiesis', 'Fetal Hemoglobin', 'Hemoglobin A', 'Hemoglobins', 'Hemorrhage', 'Rats'] | 2,424,450 | [['B01.050'], ['D02.455.426.559.389.657.410.595.176'], ['G07.690.773.875', 'G07.690.936.500'], ['G04.152.825.414', 'G09.188.343.414'], ['D12.776.124.400.303', 'D12.776.422.316.762.320'], ['D12.776.124.400.405', 'D12.776.422.316.762.380'], ['D12.776.124.400', 'D12.776.422.316.762'], ['C23.550.414'], ['B01.050.150.900.64... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterisation of the DNA-dependent ATPase activity of human DNA topoisomerase IIbeta: mutation of Ser165 in the ATPase domain reduces the ATPase activity and abolishes the in vivo complementation ability. | We report for the first time an analysis of the ATPase activity of human DNA topoisomerase (topo) IIbeta. We show that topo IIbeta is a DNA-dependent ATPase that appears to fit Michaelis-Menten kinetics. The ATPase activity is stimulated 44-fold by DNA. The k(cat) for ATP hydrolysis by human DNA topo IIbeta in the pres... | ['Adenosine Triphosphatases', 'Adenosine Triphosphate', 'Amino Acid Sequence', 'Amino Acid Substitution', 'Binding Sites', 'DNA', 'DNA Helicases', 'DNA Topoisomerases, Type II', 'DNA-Binding Proteins', 'Dose-Response Relationship, Drug', 'Genetic Complementation Test', 'Humans', 'Hydrolysis', 'Kinetics', 'Models, Molec... | 12,490,710 | [['D08.811.277.040.025'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['G02.111.570.120'], ['D13.444.308'], ['D08.811.277.040.025.159', 'D08.811.399.340'], ['D08.811.399.403.741'], ['D12.776.260'], ['G... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Construction of sperm-specific lactate dehydrogenase DNA vaccine and experimental study of its immunocontraceptive effect on mice. | Lactate dehydrogenase C4 (LDHC4) is a key enzyme for sperm metabolism. It is distributed specifically in testis and is highly immunogenic. In this study, two DNA vaccines pVAX1-hLDHC and pVAX1-mLDHC were constructed by inserting coding sequences of human and mice LDHC4 into the eukaryotic expression vector pVAX1. The p... | ['Animals', 'Contraception, Immunologic', 'Female', 'Genetic Vectors', 'Humans', 'Immunization', 'Isoenzymes', 'L-Lactate Dehydrogenase', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Sexual Behavior, Animal', 'Sperm Agglutination', 'Sperm-Ovum Interactions', 'Spermatozoa', 'Vaccines, DNA'] | 18,368,308 | [['B01.050'], ['E02.875.194.300'], ['G05.360.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['D08.811.348', 'D12.776.800.300'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['B01.050.150.900.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
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