Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Extrahepatic peribiliary glands express alpha-amylase isozymes, trypsin and pancreatic lipase: an immunohistochemical analysis. | We examined expression of alpha-amylase isozymes (pancreatic and salivary), trypsin and pancreatic lipase on the epithelium of extrahepatic peribiliary glands immunohistochemically using 53 autopsied normal extrahepatic bile ducts. Three parts of the extrahepatic bile duct (common bile duct, intrapancreatic bile duct a... | ['Adult', 'Aged', 'Ampulla of Vater', 'Bile Ducts', 'Common Bile Duct', 'Exocrine Glands', 'Humans', 'Immunohistochemistry', 'Isoenzymes', 'Lipase', 'Middle Aged', 'Pancreas', 'Trypsin', 'alpha-Amylases'] | 8,406,353 | [['M01.060.116'], ['M01.060.116.100'], ['A03.159.183.079.300.950', 'A03.556.124.684.124.236', 'A03.556.875.249.160', 'A03.734.667.500'], ['A03.159.183'], ['A03.159.183.079.300'], ['A10.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', '... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Isolation of oral spirochetes from dogs and cats and provisional identification using polymerase chain reaction (PCR) analysis specific for human plaque Treponema spp. | Identification of plaque spirochetes from dogs is rare and no studies to date report cultivation of canine or feline plaque spirochetes. Plaque samples obtained from canine and feline patients were cultured in broth media. Spirochetes cultured were subjected to microscopic evaluation and were cloned on a solid medium. ... | ['Animals', 'Cat Diseases', 'Cats', 'Dog Diseases', 'Dogs', 'Humans', 'Periodontitis', 'Polymerase Chain Reaction', 'Treponema', 'Treponemal Infections'] | 11,968,929 | [['B01.050'], ['C22.180'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.465.714.533'], ['E05.393.620.500'], ['B03.440.425.410.711.795', 'B03.851.595.795'], ['C01.150.252.400.794.840', 'C01.150.252.400.84... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of temperature-humidity index on egg-laying characteristics and related stress and immunity parameters of Japanese quails. | The aim of this study was to investigate the effect of temperature-humidity index (THI) level on productive parameters, welfare, and immunity in Japanese quails. One hundred and eighty (180) birds of Japanese quail, 14 weeks old, were used. Birds were divided randomly into three equal groups, control (at low THI, less ... | ['Animals', 'Bird Diseases', 'Corticosterone', 'Coturnix', 'Female', 'Heat Stress Disorders', 'Humidity', 'Leukocyte Count', 'Male', 'Reproduction', 'Serum Albumin', 'Serum Globulins', 'Stress, Physiological', 'Temperature'] | 26,489,416 | [['B01.050'], ['C22.131'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['B01.050.150.900.248.350.650.350'], ['C26.522'], ['G16.500.275.063.725.310', 'G16.500.750.775.310', 'N06.230.150.372', 'N06.230.300.100.725.310'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595',... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Heterogeneity analysis of Metastasis Associated in Colon Cancer 1 (MACC1) for survival prognosis of colorectal cancer patients: a retrospective cohort study. | BACKGROUND: Metastasis of colorectal cancer (CRC) is directly linked to patient survival. We previously identified the novel gene Metastasis Associated in Colon Cancer 1 (MACC1) in CRC and demonstrated its importance as metastasis inducer and prognostic biomarker. Here, we investigate the geographic expression pattern ... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Cohort Studies', 'Colorectal Neoplasms', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Retrospective Studies', 'Survival Rate', 'Trans-Activators', 'Transcription Factors'] | 25,884,643 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['B01.050.150.90... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prospective population based survey of outcome of pregnancy in diabetic women: results of the Northern Diabetic Pregnancy Audit, 1994. | OBJECTIVE: To determine whether the St Vincent declaration (1989) target of diabetic pregnancy outcome approximating non-diabetic pregnancy outcome in near to being achieved.DESIGN: Prospective collection of population based information on pregnancies in women with diabetes from all participating hospitals.SETTING: Dis... | ['Congenital Abnormalities', 'Diabetes Mellitus, Type 1', 'England', 'Female', 'Fetal Death', 'Glycated Hemoglobin A', 'Humans', 'Infant Mortality', 'Infant, Newborn', 'Obstetric Labor, Premature', 'Pregnancy', 'Pregnancy Outcome', 'Pregnancy in Diabetics', 'Prospective Studies'] | 9,274,546 | [['C16.131'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['Z01.542.363.300'], ['C13.703.223', 'C23.550.260.585'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.550.475', 'N01.224.935.698.48... | ['Diseases [C]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Air medical tracheal intubation: establishing a threshold for this QA indicator. | Endotracheal intubation is a critical skill necessary in a number of situations encountered by air medical personnel. The purpose of this study was to establish a threshold for the quality assurance indicator of successful tracheal intubation in a physician-staffed air medical system. The records of all patients transp... | ['Aircraft', 'Clinical Protocols', 'Emergency Medical Services', 'Humans', 'Intubation, Intratracheal', 'Outcome and Process Assessment, Health Care', 'Pennsylvania', 'Quality Assurance, Health Care'] | 10,112,831 | [['J01.937.285.100'], ['E02.183', 'N05.715.360.330.125'], ['N02.421.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['N04.761.559', 'N05.715.360.575'], ['Z01.107.567.875.075.550', 'Z01.107.567.875.350.550', 'Z01.107.567.875.500.550'], ['N04.761.700', 'N05.700']] | ['Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Sustained release indomethacin: a double blind comparison with indomethacin suppositories. | A double-blind crossover comparison of sustained release indomethacin capsules and indomethacin suppositories showed no efficacy advantage to either preparation. In other respects the two preparations were found to be comparable. More patients preferred the convenience of the oral route of medication when given the cho... | ['Administration, Oral', 'Arthritis, Rheumatoid', 'Capsules', 'Clinical Trials as Topic', 'Delayed-Action Preparations', 'Double-Blind Method', 'Female', 'Humans', 'Indomethacin', 'Male', 'Suppositories'] | 7,019,782 | [['E02.319.267.100'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D26.255.150'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D26.255.210', 'E02.319.300.253'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Rapid clinical effectiveness of MIF-I in the treatment of major depressive illness. | A double-blind 28 day study was conducted to compare the anti-depressant efficacy of MIF-I with that of imipramine. Twenty patients hospitalized with major depressive illness participated. Clinical responses were measured by using the Hamilton Depression Rating Scale, the Global Severity of Illness Scale, the Zung Self... | ['Adult', 'Antidepressive Agents', 'Clinical Trials as Topic', 'Depressive Disorder', 'Double-Blind Method', 'Female', 'Humans', 'Imipramine', 'MSH Release-Inhibiting Hormone', 'Male', 'Middle Aged', 'Psychiatric Status Rating Scales'] | 6,138,756 | [['M01.060.116'], ['D27.505.954.427.700.122'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['F03.600.300'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.300.240.485'], ['D06.472.699.327... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chylomicron remnants potentiate phenylephrine-induced contractions of rat aorta by an endothelium-dependent mechanism. | The effects of chylomicron remnants on endothelium-dependent contraction of rat aorta were studied in vitro. Chylomicron remnant particles were prepared in vivo from male Wistar rats and were incubated with aortic rings for 45 min before concentration contraction response curves were constructed to phenylephrine. Both ... | ['Animals', 'Aorta', 'Chylomicrons', 'Endothelin Receptor Antagonists', 'Endothelium, Vascular', 'Enzyme Inhibitors', 'In Vitro Techniques', 'Indomethacin', 'Lipoproteins', 'Male', 'Nitroarginine', 'Oxidation-Reduction', 'Peptides, Cyclic', 'Phenylephrine', 'Rats', 'Rats, Wistar', 'Receptor, Endothelin A', 'Superoxide ... | 10,924,724 | [['B01.050'], ['A07.015.114.056'], ['D10.532.183', 'D12.776.521.242'], ['D27.505.519.364'], ['A07.015.700.500', 'A10.272.491.355'], ['D27.505.519.389'], ['E05.481'], ['D03.633.100.473.420'], ['D10.532', 'D12.776.521'], ['D12.125.068.050.587', 'D12.125.095.104.587'], ['G02.700', 'G03.295.531'], ['D04.345.566', 'D12.644.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of captopril on fluctuations of blood pressure and renal blood flow in rats. | Arterial blood pressure and renal blood flow (RBF) fluctuations in rats were studied by autoregressive (AR) and autoregressive-moving average (ARMA) modeling. These estimation procedures provided greater sensitivity and frequency resolution than classic fast Fourier transform (FFT)-based methods and also require shorte... | ['Animals', 'Blood Pressure', 'Captopril', 'Female', 'Fourier Analysis', 'Homeostasis', 'Models, Biological', 'Rats', 'Rats, Wistar', 'Renal Circulation'] | 8,430,829 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D12.125.072.401.623.270'], ['E05.377', 'G17.226', 'L01.224.800.625'], ['G07.410'], ['E05.599.395'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['G08.852.725', 'G09.330.100.812']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Chick brain glutamine synthetase and Mn2+-Mg2+ interactions. | Glutamine synthetase (GS) from the chick brain was purified to apparent homogeneity by ammonium sulfate fractionation followed by affinity chromatography, electrofocusing and Sephadex G-150 chromatography. The purified enzyme showed a single band on sodium dodecyl sulfate analysis in polyacrylamide gel. By sedimentatio... | ['Animals', 'Brain', 'Brain Chemistry', 'Chickens', 'Chromatography, Affinity', 'Chromatography, Gel', 'Electrophoresis, Polyacrylamide Gel', 'Enzyme Activation', 'Glutamate-Ammonia Ligase', 'Isoelectric Focusing', 'Magnesium', 'Manganese', 'Molecular Weight'] | 2,891,060 | [['B01.050'], ['A08.186.211'], ['G02.111.150', 'G03.185'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.196.181.400.170'], ['E05.196.181.400.250'], ['E05.196.401.402', 'E05.301.300.319'], ['G02.111.263', 'G03.328'], ['D08.811.464.259.200.600'], ['E05.196.401.663', 'E05.301.300.663'], ['D01.268.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Short-term outcomes of laparoscopic surgery for colorectal cancer in oldest-old patients. | BACKGROUND/AIMS: Oldest-old patients generally have several comorbidities, and laparoscopic-assisted colectomy (LAC) has not been performed on these patients. However, the surgical technique of LAC has improved, and its indications have been extended. The aim of this study was to evaluate the safety and effectiveness o... | ['Age Factors', 'Aged, 80 and over', 'Colectomy', 'Colorectal Neoplasms', 'Comorbidity', 'Female', 'Humans', 'Japan', 'Laparoscopy', 'Male', 'Retrospective Studies', 'Treatment Outcome'] | 25,678,189 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100.080'], ['E04.210.219'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['N05.715.350.225', 'N06.850.490.687'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z0... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A bioassay system of autologous human endothelial, smooth muscle cells, and leukocytes for use in drug discovery, phenotyping, and tissue engineering. | Blood vessels are comprised of endothelial and smooth muscle cells. Obtaining both types of cells from vessels of living donors is not possible without invasive surgery. To address this, we have devised a strategy whereby human endothelial and smooth muscle cells derived from blood progenitors from the same donor could... | ['Biological Assay', 'Cells, Cultured', 'Coculture Techniques', 'Cytokines', 'Drug Discovery', 'Endothelial Cells', 'Humans', 'Interleukin-6', 'Leukocytes', 'Muscle, Smooth, Vascular', 'Myocytes, Smooth Muscle', 'Phenotype', 'Tissue Engineering', 'Tumor Necrosis Factor-alpha'] | 31,914,612 | [['E05.091'], ['A11.251'], ['E05.481.500.374'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['A11.436.275'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['A11.118.637', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Anti-endothelial cell antibodies in patients with coronary atherosclerosis. | Anti-endothelial cell antibodies (AECA) have been shown to possess endothelial cell activation properties and to harbor pathogenic potential in experimental animal models of autoimmune systemic disorders. Atherosclerosis is a form of an inflammatory condition in which the immune system has been shown to be involved. Th... | ['Aged', 'Autoantibodies', 'Cells, Cultured', 'Coronary Angiography', 'Coronary Artery Disease', 'E-Selectin', 'Endothelium, Vascular', 'Female', 'Humans', 'Male', 'Middle Aged'] | 10,963,807 | [['M01.060.116.100'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['A11.251'], ['E01.370.350.130.625', 'E01.370.350.700.060.200', 'E01.370.370.050.200', 'E01.370.370.380.200'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['D12.776.395.550.200... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dosimetric influence of seed spacers and end-weld thickness for permanent prostate brachytherapy. | PURPOSE: The aim of this study was to analyze the dosimetric influence of conventional spacers and a cobalt chloride complex contrast (C4) agent, a novel marker for MRI that can also serve as a seed spacer, adjacent to (103)Pd, (125)I, and (131)Cs sources for permanent prostate brachytherapy.METHODS AND MATERIALS: Mont... | ['Brachytherapy', 'Humans', 'Male', 'Models, Theoretical', 'Monte Carlo Method', 'Prostatic Neoplasms', 'Radiometry', 'Radiotherapy Dosage'] | 24,139,289 | [['E02.815.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['E05.799'], ['E02.815.639']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Motivational interviewing as a mechanism for change in men who batter: a randomized controlled trial. | The present study reports on the potential effectiveness of motivational interviewing (MI) in changing the way batterers think about their violent behavior. Thirty-three domestic violence offenders who were court-mandated to treatment were randomly assigned to MI or a control condition before attending their first mand... | ['Adult', 'Cognitive Behavioral Therapy', 'Community Health Centers', 'Community Networks', 'Cooperative Behavior', 'Humans', 'Interpersonal Relations', 'Interview, Psychological', 'Male', 'Maryland', 'Middle Aged', 'Motivation', 'Patient Acceptance of Health Care', 'Risk Reduction Behavior', 'Secondary Prevention', 'S... | 18,958,985 | [['M01.060.116'], ['F04.754.137.350'], ['N02.278.035.128'], ['I01.880.853.500.300', 'L01.313.500.750.300.184', 'N02.421.143.202'], ['F01.145.813.115'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['F04.669.599'], ['Z01.107.567.875.075.418', 'Z01.107.567.875.500.500'], ['M01.060.116.630'], ['F01.65... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
[Effects of oxygenated volume expander on hemorrhagic shock]. | 36 dogs were divided into 3 groups: group A were administered with non-oxygenated crystalloid solution as a control; group B, with oxygenated crystalloid solution; group C, with oxygenated no 3 perfluorocarbon emulsion (PFC-O2) as volume expander. Result of measurements of serum CPK, LDH, lactic acid, gas analysis, MAP... | ['Animals', 'Creatine Kinase', 'Dogs', 'Female', 'Fluorocarbons', 'Hemodynamics', 'L-Lactate Dehydrogenase', 'Lung', 'Male', 'Oxygen', 'Plasma Substitutes', 'Potassium', 'Potassium Compounds', 'Shock, Hemorrhagic'] | 2,364,810 | [['B01.050'], ['D08.811.913.696.640.150'], ['B01.050.150.900.649.313.750.250.216.200'], ['D02.455.526.510.435'], ['G09.330.380'], ['D08.811.682.047.551.400', 'D08.811.682.047.820.493'], ['A04.411'], ['D01.268.185.550', 'D01.362.670'], ['D27.505.954.502.140.500'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Listening to neutral or self-selected motivational music during warm-up to improve short-term maximal performance in soccer players: Effect of time of day. | The present experiment examined the effects of listening to different types of music during warm-up on the diurnal variation of short-term maximal performance (STMP) in soccer players, using a 3 ? 2 mixed design with factors "Condition" (warm-up with self-selected motivational-music (WUMM) vs. warm-up with neutral-musi... | ['Athletic Performance', 'Circadian Rhythm', 'Emotions', 'Exercise Test', 'Humans', 'Male', 'Motivation', 'Music', 'Soccer', 'Young Adult'] | 30,817,975 | [['I03.450.642.845.054'], ['G07.180.562.190'], ['F01.470'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.658', 'F01.752.543.500.750'], ['K01.602'], ['I03.450.642.845.800'], ['M01.060.116.815']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Humanities [K]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
The MDM2 RING-finger domain is required to promote p53 nuclear export. | MDM2 can bind to p53 and promote its ubiquitination and subsequent degradation by the proteasome. Current models propose that nuclear export of p53 is required for MDM2-mediated degradation, although the function of MDM2 in p53 nuclear export has not been clarified. Here we show that MDM2 can promote the nuclear export... | ['Active Transport, Cell Nucleus', 'Cell Nucleus', 'Humans', 'Nuclear Proteins', 'Protein Structure, Tertiary', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-mdm2', 'Tumor Cells, Cultured', 'Tumor Suppressor Protein p53', 'Ubiquitins', 'Zinc Fingers'] | 10,980,696 | [['G03.143.310.100', 'G03.143.700.100'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.660'], ['G02.111.570.820.709.610'], ['D12.776.624.664.700'], ['D08.811.464.938.750.562', 'D12.776.624.664.700.185', 'D12.776.660.764'], ['A11.251.860'], ['D12.776.157.6... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Preparation of dummy molecularly imprinted polymers based on dextran-modified magnetic nanoparticles Fe3 | Novel dummy magnetic molecularly imprinted polymers (dex-MMIPs) were prepared for highly selective recognition and fast enrichment of acrylamide (AA) in potato chips. Propionamide (PA) was used as dummy template molecule and the Fe3O4 nanoparticles modified with carboxymethyl dextran were developed as supports. Methacr... | ['Acrylamide', 'Adsorption', 'Chromatography, High Pressure Liquid', 'Cooking', 'Dextrans', 'Food Analysis', 'Food Contamination', 'Magnetics', 'Magnetite Nanoparticles', 'Methacrylates', 'Microscopy, Electron, Transmission', 'Molecular Imprinting', 'Niacinamide', 'Polymers', 'Solanum tuberosum', 'Spectroscopy, Fourier... | 32,109,657 | [['D02.065.122.015', 'D02.241.081.069.094.015'], ['G01.030', 'G02.020'], ['E05.196.181.400.300'], ['J01.576.423.200.200'], ['D05.750.078.562.272', 'D09.698.365.272'], ['E05.362', 'J01.576.423.850.100'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.249'], ['H01.671.493'], ['J01.637.512.600.500.144... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
A study of schizophrenic brains by computerized tomography scans. | The brains of 55 schizophrenic patients and 65 controls were examined using computerized tomography scans. The width of the interhemispheric fissure and the third ventricle, and the volume of the lateral ventricles in the schizophrenic patients were significantly larger than those obtained in the controls. The extensio... | ['Adolescent', 'Adult', 'Aged', 'Brain', 'Child', 'Epilepsy', 'Functional Laterality', 'Humans', 'Middle Aged', 'Migraine Disorders', 'Neurotic Disorders', 'Schizophrenia', 'Tomography, X-Ray Computed'] | 7,274,871 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['A08.186.211'], ['M01.060.406'], ['C10.228.140.490'], ['F02.830.297.425', 'G11.561.225.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.228.140.546.399.750'], ['F03.080.550', 'F03.650'], ['F03.700.750'], ['E01.370.350.350.810', '... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The health of Cree, Inuit and southern Quebec women: similarities and differences. | Using the data from a number of the surveys conducted over the last 10 years by Sant? Qu?bec, this study examines the health characteristics of two populations of Aboriginal women of northern Quebec compared to those of women in the rest of the province. The northern populations had a larger proportion of young women. ... | ['Adolescent', 'Adult', 'Aged', 'Cross-Sectional Studies', 'Demography', 'Female', 'Health Surveys', 'Humans', 'Indians, North American', 'Inuits', 'Middle Aged', 'Quebec', 'Risk Factors', 'Surveys and Questionnaires', "Women's Health"] | 10,927,851 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.686.508.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Mathematic modeling of the risk of HBV, HCV, and HIV transmission by window-phase donations not detected by NAT. | BACKGROUND: Blood transfusion centers around the world have introduced minipool NAT to reduce the risk of HBV, HCV, and HIV transmission by blood donations drawn in the infectious window phase. What would be the reduction in the residual risk when minipool NAT would be replaced by single-donation NAT?STUDY DESIGN AND M... | ['Blood Donors', 'Blood Transfusion', 'Europe', 'False Negative Reactions', 'Gene Amplification', 'HIV', 'HIV Infections', 'Hepacivirus', 'Hepatitis B', 'Hepatitis B virus', 'Hepatitis C', 'Humans', 'Incidence', 'Models, Theoretical', 'Probability', 'RNA, Viral', 'Risk Assessment', 'Safety', 'Sensitivity and Specificit... | 12,084,161 | [['M01.898.313'], ['E02.095.135'], ['Z01.542'], ['E01.354.340'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['B04.820.650.589.650.350'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Hospital resource use and cost of treatment with linezolid versus teicoplanin for treatment of serious gram-positive bacterial infections among hospitalized patients from South America and Mexico: results from a multicenter trial. | BACKGROUND: Linezolid is a novel oxazolidinone antibiotic that is effective for the treatment of gram-positive bacterial infections. The oral formulation has the potential to reduce length of stay (LOS) when used as a substitute for parenteral glycopeptide antibiotics. In a recent multinational trial comparing linezoli... | ['Acetamides', 'Administration, Oral', 'Adolescent', 'Adult', 'Anti-Bacterial Agents', 'Anti-Infective Agents', 'Female', 'Gram-Positive Bacterial Infections', 'Hospital Costs', 'Humans', 'Injections, Intramuscular', 'Injections, Intravenous', 'Linezolid', 'Male', 'Mexico', 'Middle Aged', 'Oxazolidinones', 'South Ameri... | 12,860,502 | [['D02.065.064', 'D02.241.081.018.110'], ['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.085'], ['D27.505.954.122'], ['C01.150.252.410'], ['N03.219.151.400.687', 'N03.219.262.500', 'N05.300.375.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.460'], ['E02.319.267.082.75... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Direct immobilization of cupredoxin azurin modified by site-directed mutagenesis on gold surface. | For making efficient bioelectronic device, we have developed novel immobilization method of cupredoxin azurin modified on gold (Au) surface. A recombinant protein with cysteine residue by using site-directed mutagenesis was designed and then directly immobilized on Au surface without any chemical linker. The immobiliza... | ['Adsorption', 'Azurin', 'Electrochemistry', 'Gold', 'Microscopy, Scanning Tunneling', 'Mutagenesis, Site-Directed', 'Pseudomonas aeruginosa', 'Surface Plasmon Resonance'] | 18,667,275 | [['G01.030', 'G02.020'], ['D12.776.097.100', 'D12.776.556.080'], ['H01.181.529.307'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['E01.370.350.515.666.500', 'E05.595.666.500'], ['E05.393.420.601.575'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050'], ['E05.196.890', 'E05.601.043.700']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Intravenous immunoglobulin treatment in women with recurrent abortions: increased cytokine levels and reduced Th1/Th2 lymphocyte ratio in peripheral blood. | PROBLEM: The aim of this study was to investigate changes in peripheral blood Th1/Th2 cytokine levels and lymphocyte ratios after massive intravenous immunoglobulin (MIVIg) treatment for women with recurrent spontaneous abortion (RSA) of unexplained etiology.METHOD OF STUDY: Serum Th1 (IFN-gamma, TNF-alpha) and Th2 cyt... | ['Abortion, Habitual', 'Animals', 'Cytokines', 'Female', 'Humans', 'Immunoglobulins, Intravenous', 'Immunotherapy', 'Mice', 'Th1 Cells', 'Th2 Cells'] | 12,765,346 | [['C13.703.039.089'], ['B01.050'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.393.536', 'D12.776.124.486.485.114.632', 'D12.776.124.790.651.114.632', 'D12.776.377.715.548.114.632'], ['E02.095.465.425'], ['B01.050.150.900.649.313.... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Endoscopic, transoral, reduction of epiglottic entrapment via wire snare technique. | OBJECTIVE: To describe the use of a wire snare technique for epiglottic entrapment.STUDY DESIGN: Case series.ANIMALS: Eight adult horses.METHODS: Under general anesthesia, a modified mouth gag was placed in the oropharynx. An endoscope was passed through the gag until there was adequate visualization of the entrapped e... | ['Anesthesia, General', 'Animals', 'Epiglottis', 'Horse Diseases', 'Horses', 'Laryngeal Diseases', 'Laryngoscopy', 'Postoperative Complications', 'Treatment Outcome'] | 25,289,732 | [['E03.155.197'], ['B01.050'], ['A02.165.257.625.411', 'A02.165.407.500.411', 'A04.329.591.411'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472'], ['C08.360', 'C09.400'], ['E01.370.386.460', 'E01.370.388.250.525', 'E04.502.250.525', 'E04.580.373'], ['C23.550.767'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Relaxin induces up-regulation of ADAM10 metalloprotease in RXFP1-expressing cells by PI3K/AKT signaling. | ADAM10 metalloprotease is required for activation of Notch-1, a transmembrane receptor regulating cell differentiation, proliferation and apoptosis, whose intracellular proteolytic fragment NICD mediates some key cardiovascular effects of the hormone relaxin (RLX). This study demonstrates the involvement of ADAM10 and ... | ['ADAM10 Protein', 'Animals', 'Fibroblasts', 'Humans', 'Mice', 'Myocytes, Cardiac', 'NIH 3T3 Cells', 'Phosphatidylinositol 3-Kinases', 'Phosphorylation', 'Protein Domains', 'Proto-Oncogene Proteins c-akt', 'Rats', 'Receptors, G-Protein-Coupled', 'Receptors, Notch', 'Receptors, Peptide', 'Relaxin', 'Signal Transduction'... | 29,180,109 | [['D08.811.277.656.675.374.102.250', 'D09.400.430.500.250', 'D12.776.395.033.250'], ['B01.050'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['A07.541.704.570', 'A10.690.552.750.570', 'A11.620.500'], ['A11.251.210.100.550', 'A11.329.228.100.550'], ['D08... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular Mobility Suppression of Ibuprofen-Rich Amorphous Nanodroplets by HPMC Revealed by NMR Relaxometry and Its Significance with Respect to Crystallization Inhibition. | In the present study, the molecular state of drug-rich amorphous nanodroplets was evaluated using NMR techniques to reveal the mechanism underlying the crystallization inhibition of drug-rich amorphous nanodroplets by a polymer. Ibuprofen (IBP) with a low glass transition temperature was used for direct characterizatio... | ['Crystallization', 'Hypromellose Derivatives', 'Ibuprofen', 'Magnetic Resonance Spectroscopy', 'Nanostructures'] | 31,661,287 | [['E05.196.300', 'G02.171'], ['D05.750.078.562.180.357', 'D09.698.365.180.455', 'D25.720.099.500.719', 'J01.637.051.720.099.500.719'], ['D02.241.223.701.430'], ['E05.196.867.519'], ['J01.637.512']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Self-regulation of commitment to reduce cigarette consumption: mental contrasting of future with reality. | The model of fantasy realisation (Oettingen, 2000) specifies mental contrasting of a positive future with negative reality as a strategy that creates strong goal commitments. We propose that fantasies about a positive and negative future produce strong goal commitments when contrasted with the respective reality. The p... | ['Adult', 'Fantasy', 'Female', 'Germany', 'Humans', 'Internal-External Control', 'Motivation', 'Self Efficacy', 'Smoking Cessation', 'Surveys and Questionnaires', 'Young Adult'] | 20,204,943 | [['M01.060.116'], ['F01.393.351', 'F02.463.188.634.507'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.379'], ['F01.658', 'F01.752.543.500.750'], ['F01.752.747.792.700'], ['F01.145.488.732'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Barrier contraceptive methods and preeclampsia. | Recent investigations have suggested that women who use barrier methods of contraception may be at increased risk for preeclampsia. We used data from two prospective pregnancy studies to examine the relationship between contraceptive use before conception and preeclampsia. The preeclampsia rates among women using barri... | ['Adolescent', 'Adult', 'Contraceptive Devices, Female', 'Female', 'Humans', 'Odds Ratio', 'Parity', 'Pre-Eclampsia', 'Pregnancy', 'Prospective Studies', 'Risk Factors'] | 1,984,127 | [['M01.060.057'], ['M01.060.116'], ['E07.190.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.600', 'G17.680.500', 'N05.715.360.750.625.590', 'N06.850.520.830.600.600'], ['G08.686.677', 'G08.686.784.769.472', 'N06.850.490.812.600'], ['C13.703.395.249'], ['G08.686.784.769'], ['E05.318.372.500.75... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Variation of endogenous hormones in formation of microtuber of Dioscorea opposite in vitro]. | OBJECTIVE: Through analysis of variation and function of 5 main endogenous hormones in the formation of microtuber of Dioscorea opposite in vitro to explore the physiological and biochemical mechanism of microtuber development.METHOD: When microtubers were induced on MS + 6-BA 1.5 mg x L(-1) + NAA 1.5 mg x L(-1) + sucr... | ['Abscisic Acid', 'Cyclopentanes', 'Dioscorea', 'Gibberellins', 'Indoleacetic Acids', 'Isopentenyladenosine', 'Oxylipins', 'Plant Growth Regulators', 'Plant Tubers'] | 21,322,938 | [['D02.241.223.268.034', 'D02.455.326.271.665.202.061', 'D02.455.426.392.368.367.379.249.024', 'D02.455.849.131.061', 'D02.455.849.765.521.500'], ['D02.455.426.392.368.450'], ['B01.650.940.800.575.912.250.325.500'], ['D02.455.849.291.239.500'], ['D03.066.288', 'D03.633.100.473.404'], ['D03.633.100.759.138.525.350', 'D0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Can a sentinel node mapping algorithm detect all positive lymph nodes in cervical cancer? | OBJECTIVES: The aims of this study were to determine the sensitivity and negative predictive value (NPV) of sentinel lymph node (SLN) detection in cervical cancer using a combination technique, and to test the SLN algorithm that was proposed by the Memorial Sloan Kettering Cancer Center (MSKCC).METHODS: The study inclu... | ['Adenocarcinoma', 'Adult', 'Aged', 'Algorithms', 'Carcinoma, Squamous Cell', 'Female', 'Follow-Up Studies', 'Humans', 'Hysterectomy', 'Longitudinal Studies', 'Lymph Nodes', 'Lymphatic Metastasis', 'Lymphoscintigraphy', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Staging', 'Prognosis', 'Prospective Studies', 'Sen... | 25,404,479 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.950.300.399'], ['E05.318.372.500.7... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Isolation and purification of an unspecific component from human serum albumin, typical for pathology]. | Albumin from blood serum of healthy persons and from patients with various pathologies and different severity of diseases was characterized using isoelectric focusing in borate-polyol system. In all the pathologies studied a new component occurred, which had an isoelectric point at pH 5.5 and which was not found in fre... | ['Clinical Laboratory Techniques', 'Humans', 'Isoelectric Focusing', 'Protein Conformation', 'Reference Values', 'Serum Albumin'] | 7,281,554 | [['E01.370.225', 'E05.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.401.663', 'E05.301.300.663'], ['G02.111.570.820.709'], ['E05.978.810'], ['D12.776.034.841', 'D12.776.124.727']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthetic human growth hormone releasing factor (h-GRF-I-44-NH2) dose response effect on growth hormone and prolactin secretion in healthy adult men. | The dose-effect relationship of an i.v. bolus of synthetic h-GRF-44 on growth-hormone and prolactin secretion has been studied. Seven healthy adult volunteers received in a random order h-GRF-44 2.5, 5, 10, 20, 40 and 80 micrograms and a placebo. Plasma growth hormone (GH) was determined between 30 min before and 240 m... | ['Adult', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Growth Hormone', 'Growth Hormone-Releasing Hormone', 'Humans', 'Male', 'Peptide Fragments', 'Prolactin', 'Time Factors'] | 3,082,645 | [['M01.060.116'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['D06.472.699.327.740.860', 'D12.644.400.400.740.860', 'D12.644.548.365.740.860', 'D12.776.631.650.405.740.860'], ['B01.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The effect of percutaneous tibial nerve stimulation (PTNS) on sexual function: a systematic review and meta-analysis. | INTRODUCTION: Percutaneous tibial nerve stimulation (PTNS) is now an established treatment of pelvic floor dysfunction such as overactive bladder, faecal incontinence or voiding dysfunction. Prevalence of female sexual dysfunction is high in this group. We aim to examine the effect of PTNS on sexual function in this pa... | ['Humans', 'Pelvic Floor Disorders', 'Sexual Dysfunction, Physiological', 'Tibial Nerve', 'Transcutaneous Electric Nerve Stimulation'] | 31,278,415 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.483', 'C13.351.625', 'C13.703.565'], ['C12.294.644', 'C13.351.500.665'], ['A08.800.800.720.450.760.820'], ['E02.331.800', 'E02.779.468.800', 'E02.831.535.468.800', 'E03.091.823']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Compounds with positive inotropic activity, III: Synthesis of 4-aminoquinoline derivatives as potential positive inotropic agents. | Anilinoacrylic acid derivatives 2-4 are the key intermediates from which 1-alkyl substituted 4-aminoquinoline 10-15 as well as 4-alkylaminoquinoline derivatives 16-23 are synthesized and examined for positive inotropic activity on isolated left atria and papillary muscles from guinea-pig. Structure activity relationshi... | ['Aminoquinolines', 'Animals', 'Cardiotonic Agents', 'Chemical Phenomena', 'Chemistry, Physical', 'Guinea Pigs', 'In Vitro Techniques', 'Myocardial Contraction', 'Papillary Muscles'] | 2,288,483 | [['D03.633.100.810.050'], ['B01.050'], ['D27.505.954.411.222', 'D27.720.799.080'], ['G02'], ['H01.181.529'], ['B01.050.150.900.649.313.992.550'], ['E05.481'], ['G09.330.580', 'G11.427.494.570'], ['A02.633.580.680', 'A07.541.510.619', 'A07.541.704.750']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Early postoperative serum cystatin C predicts severe acute kidney injury following cardiac surgery: a post-hoc analysis of a randomized controlled trial. | OBJECTIVE: Acute kidney injury (AKI) after cardiac surgery procedures is associated with poor patient outcomes. Cystatin C as a marker for renal failure has been shown to be of prognostic value; however, a wide range of its predictive accuracy has been reported. The aim of the study was to evaluate whether the measurem... | ['Acute Kidney Injury', 'Aged', 'Aged, 80 and over', 'Cardiac Surgical Procedures', 'Cystatin C', 'Early Diagnosis', 'Female', 'Follow-Up Studies', 'Humans', 'Immunoassay', 'Male', 'Middle Aged', 'Postoperative Complications', 'Predictive Value of Tests', 'Prospective Studies', 'Time Factors'] | 24,397,879 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.100.376', 'E04.928.220'], ['D12.776.215.300'], ['E01.390'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566',... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Pulmonary cryptococcosis in rheumatoid arthritis (RA) patients: comparison of imaging characteristics among RA, acquired immunodeficiency syndrome, and immunocompetent patients. | PURPOSE: The imaging characteristics of cryptococcosis in rheumatoid arthritis (RA) patients were analyzed by comparing them with those of acquired immunodeficiency syndrome (AIDS) and immunocompetent patients, and the imaging findings were correlated with pathological findings.METHODS: Two radiologists retrospectively... | ['Acquired Immunodeficiency Syndrome', 'Adult', 'Aged', 'Aged, 80 and over', 'Arthritis, Rheumatoid', 'Cryptococcosis', 'Diagnosis, Differential', 'Female', 'Humans', 'Immunocompetence', 'Lung Diseases, Fungal', 'Male', 'Middle Aged', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Tomography, X-Ray Compu... | 23,954,014 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['C01.150.703.248']... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Factors associated with spinal fusion after posterior fossa decompression in pediatric patients with Chiari I malformation and scoliosis. | OBJECTIVE The authors performed a study to identify clinical characteristics of pediatric patients diagnosed with Chiari I malformation and scoliosis associated with a need for spinal fusion after posterior fossa decompression when managing the scoliotic curve. METHODS The authors conducted a multicenter retrospective ... | ['Adolescent', 'Arnold-Chiari Malformation', 'Child', 'Cohort Studies', 'Decompression, Surgical', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Retrospective Studies', 'Scoliosis', 'Spinal Fusion', 'Treatment Outcome', 'Young Adult'] | 27,589,598 | [['M01.060.057'], ['C10.500.680.291', 'C16.131.666.680.291'], ['M01.060.406'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E04.188'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Five new phorbol esters with cytotoxic and selective anti-inflammatory activities from Croton tiglium. | Five new phorbol esters, (four phorbol diesters, 1-4, and one 4-deoxy-4á-phorbol diester, 5), as well as four known phorbol esters analogues (6-9) were isolated and identified from the branches and leaves of Croton tiglium. Their structures were elucidated mainly by extensive NMR spectroscopic, and mass spectrometric a... | ['Anti-Inflammatory Agents, Non-Steroidal', 'Cell Line', 'Cell Proliferation', 'Croton', 'Cyclooxygenase 1', 'Cyclooxygenase 2', 'Cyclooxygenase Inhibitors', 'Dose-Response Relationship, Drug', 'Humans', 'Molecular Structure', 'Phorbol Esters', 'Structure-Activity Relationship'] | 25,819,096 | [['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'], ['B01.650.940.800.575.912.250.859.797.438.199'], ['D08.811.600.720.500'], ['D08.811.600.720.750'], ['D27.505.519.389.310', 'D27.505.696.663.850.014.040.500.500', 'D27.505.954.158.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Exploring the predictors of home telehealth uptake by elderly Australian healthcare consumers. | BACKGROUND: Despite the significant access and cost-saving potential of telehealth, the uptake of telehealth services in Australia has been sporadic. Understanding the factors that drive the uptake of home-telehealth services from the consumer perspective has received scant attention in the literature.AIM: The aim of t... | ['Aged', 'Australia', 'Consumer Behavior', 'Female', 'Health Knowledge, Attitudes, Practice', 'Health Services Accessibility', 'Home Care Services', 'Humans', 'Male', 'Middle Aged', 'Regression Analysis', 'Risk Factors', 'Rural Population', 'Telemedicine'] | 26,391,512 | [['M01.060.116.100'], ['Z01.639.100', 'Z01.678.100.373'], ['F01.145.236'], ['F01.100.150.500', 'N05.300.150.410'], ['N04.590.374.350', 'N05.300.430'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830... | ['Named Groups [M]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
What makes the hedonic experience of a meal in a top restaurant special and retrievable in the long term? Meal-related, social and personality factors. | Knowing what makes a top gastronomy experience unique and retrievable in the long term is of interest for scientific and economic reasons. Recent attempts to isolate predictors of the hedonic evaluation of food have afforded several factors, such as individual and social attributes, or liking/disliking profiles. Howeve... | ['Adult', 'Attitude', 'Female', 'Humans', 'Male', 'Meals', 'Middle Aged', 'Personality', 'Pleasure', 'Restaurants', 'Surveys and Questionnaires'] | 29,501,681 | [['M01.060.116'], ['F01.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.300.590', 'J02.500.590'], ['M01.060.116.630'], ['F01.752'], ['F01.470.867', 'F02.830.816.492'], ['J01.576.423.500.700', 'J03.813'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Lower lid blepharoplasty with skin flap and muscle split. | A skin flap, muscle split lower eyelidplasty is recommended for the management of excess skin of the lower eyelids associated with herniated infraorbital fat pads. Precise fat pad removal and skin excision are necessary. | ['Eyelids', 'Humans', 'Surgery, Plastic', 'Surgical Flaps'] | 3,349,742 | [['A01.456.505.420.504', 'A09.371.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.810.788'], ['A10.850.710', 'E07.862.710']] | ['Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
A New Treatment Strategy for Inactivating Algae in Ballast Water Based on Multi-Trial Injections of Chlorine. | Ships' ballast water can carry aquatic organisms into foreign ecosystems. In our previous studies, a concept using ion exchange membrane electrolysis to treat ballast water has been proven. In addition to other substantial approaches, a new strategy for inactivating algae is proposed based on the developed ballast wate... | ['Chlorine', 'Chlorophyta', 'Electrolysis', 'Ion Exchange Resins', 'Ships', 'Water Purification'] | 26,068,239 | [['D01.268.380.150', 'D01.362.225'], ['B01.650.940.150'], ['E05.301.250'], ['D27.720.470.420'], ['J01.937.817'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Reduced Fatigue in Passive Versus Active Recovery: An Examination of Repeated-Change-of-Direction Sprints in Basketball Players. | PURPOSE: To investigate the physiological and performance effects of active and passive recovery between repeated-change-of-direction sprints.METHODS: Eight semiprofessional basketball players (age: 19.9 [1.5] y; stature: 183.0 [9.6] cm; body mass: 77.7 [16.9] kg; body fat: 11.8% [6.3%]; and peak oxygen consumption: 46... | ['Adolescent', 'Athletes', 'Athletic Performance', 'Basketball', 'Cross-Over Studies', 'Fatigue', 'Female', 'Heart Rate', 'Humans', 'Lactic Acid', 'Male', 'Oxygen Consumption', 'Running', 'Stress, Physiological', 'Young Adult'] | 29,466,079 | [['M01.060.057'], ['M01.072'], ['I03.450.642.845.054'], ['I03.450.642.845.117'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['C23.888.369'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.241.511.459.450'], ['G03.680'], ['G11.427.410.568.610', ... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Leiomyosarcoma of the small intestine. Review of the literature apropos of 3 cases]. | This study reports three cases of leiomyosarcoma of the small intestine (a rare malignant neoplasm) presenting in our department of general surgery over a period of ten years. Tumors in these three patients were located in the jejunum and clinical features included severe gastrointestinal bleeding, intestinal obstructi... | ['Aged', 'Female', 'Humans', 'Jejunal Neoplasms', 'Jejunum', 'Leiomyosarcoma', 'Male', 'Middle Aged', 'Prognosis'] | 7,802,436 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.476.411.523', 'C06.301.371.411.523', 'C06.405.249.411.523', 'C06.405.469.491.523', 'C06.405.469.600.523'], ['A03.556.124.684.500', 'A03.556.249.750'], ['C04.557.450.590.455', 'C04.557.450.795.455'], ['M01.060.116.630'], ['E01.789']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Do ancillary properties of antihypertensive drugs explain the outcome results of recent trials? | BACKGROUND: In a quantitative overview of published trials, we investigated whether some pharmacological properties of antihypertensive drugs, besides reduction in blood pressure, explain cardiovascular outcomes in hypertensive or high-risk patients.METHODS: Across trials, using meta-regression, we correlated odds rati... | ['Antihypertensive Agents', 'Blood Pressure Determination', 'Cardiovascular Diseases', 'Female', 'Humans', 'Hypertension', 'Linear Models', 'Male', 'Odds Ratio', 'Predictive Value of Tests', 'Prognosis', 'Randomized Controlled Trials as Topic', 'Risk Assessment', 'Risk Factors', 'Sensitivity and Specificity', 'Survival... | 12,243,374 | [['D27.505.954.411.162'], ['E01.370.370.140', 'E01.370.600.100'], ['C14'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['E0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Coordination of care for pediatric AIDS: the development of a Maternal-Child HIV Task Force. | As of 1988, 78% of all reported pediatric human immunodeficiency virus (HIV) infections were secondary to maternal transmission. With blood screening and treatment of Factor 8 essentially eliminating transfusion as a vector for HIV, the issues of obstetrical and pediatric HIV infections are functionally identical. This... | ['Acquired Immunodeficiency Syndrome', 'Child', 'Combined Modality Therapy', 'Health Facilities', 'Hospitals, University', 'Humans', 'Los Angeles', 'Maternal-Child Health Centers', 'Risk Factors'] | 2,768,488 | [['C01.221.250.875.040', 'C01.221.812.640.400.040', 'C01.778.640.400.040', 'C01.925.782.815.616.400.040', 'C01.925.813.400.040', 'C01.925.839.040', 'C20.673.480.040'], ['M01.060.406'], ['E02.186'], ['N02.278'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.56... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[The specialist-dentist regulations and the program for the traing for the "dental specialist for general dentistry"]. | The Central Professional Committee for General Stomatology provides the instructors and the dentists training for a speciality with an interpretation of the regulations for the diploma of specialist physician/specialist dentist of May 23, 1974, and of the educational program. Advice and recommendations are given for th... | ['Education, Dental, Continuing', 'General Practice, Dental', 'Socialism'] | 1,058,540 | [['I02.358.212.249', 'I02.358.274.316'], ['H02.163.342'], ['I01.696.798']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas. | Amplification of chromosomal DNA is thought to be one of the mechanisms that activate cancer-related genes in tumors. In a recent study, we identified high copy-number amplification at 11q21-q23 in cell lines derived from esophageal squamous cell carcinomas (ESCs) using comparative genomic hybridization. Because 11q21-... | ['Apoptosis', 'Carcinoma, Squamous Cell', 'Chromosome Mapping', 'Chromosomes, Human, Pair 11', 'Esophageal Neoplasms', 'Gene Amplification', 'Humans', 'In Situ Hybridization, Fluorescence', 'Inhibitor of Apoptosis Proteins', 'Protein Biosynthesis', 'Proteins', 'RNA, Messenger', 'Tumor Cells, Cultured', 'Ubiquitin-Prote... | 11,559,525 | [['G04.146.954.035'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.393.183'], ['A11.284.187.520.300.325.355', 'G05.360.162.520.300.325.355'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['B01.050.150.900... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Migration, integration, and differentiation of hippocampus-derived neurosphere cells after transplantation into injured rat spinal cord. | Hippocampus-derived neurospheres were prepared from transgenic rat fetuses expressing green fluorescent protein (GFP), and transplanted into an alginate-filled lesion of young rat spinal cord. One, two and four weeks after transplantation, a large number of grafted cells survived, many of which expressed immunoreactivi... | ['Alginates', 'Animals', 'Animals, Genetically Modified', 'Brain Tissue Transplantation', 'Cell Differentiation', 'Cell Movement', 'Cells, Cultured', 'Glial Fibrillary Acidic Protein', 'Graft Survival', 'Green Fluorescent Proteins', 'Hippocampus', 'Immunohistochemistry', 'Indicators and Reagents', 'Luminescent Proteins... | 11,602,338 | [['D09.698.068'], ['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['E02.095.147.725.090', 'E04.525.090', 'E04.936.580.090'], ['G04.152'], ['G04.198', 'G07.568.500.180'], ['A11.251'], ['D05.750.078.593.400', 'D12.776.220.475.400'], ['G12.875.545.340'], ['D12.776.532.265'], ['A08.186.211.180.405', 'A08.186.211.200.885.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Achyrocline satureioides essential oil-loaded in nanocapsules reduces cytotoxic damage in liver of rats infected by Trypanosoma evansi. | The aim of this study was to evaluate whether the treatment with Achyrocline satureioides essential oil-loaded in nanocapsules (AS-NC) is able to protect the hepatic tissue against cytotoxic damage caused by Trypanosoma evansi. Thus, the rats were divided into four groups (n = 6 per group): uninfected/saline, uninfecte... | ['Achyrocline', 'Animals', 'Female', 'Liver', 'Nanocapsules', 'Nitric Oxide', 'Oils, Volatile', 'Plant Extracts', 'Rats', 'Reactive Oxygen Species', 'Trypanosoma', 'Trypanosomiasis'] | 28,027,942 | [['B01.650.940.800.575.912.250.100.041'], ['B01.050'], ['A03.620'], ['D26.255.260.575', 'E02.319.300.380.575', 'J01.637.512.600.575'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['D10.627.675'], ['D20.215.784.500', 'D26.667'], ['B01.050.150.900.649.313.992.635.505.700'], ['D01.339.431... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Community composition of soil bacteria nearly a decade after a fire in a tropical rainforest in East Kalimantan, Indonesia. | Soil bacterial community compositions in burnt and unburnt areas in a tropical rainforest in East Kalimantan, Indonesia, were investigated 8 and 9 years after a fire by denaturing gradient gel electrophoresis analysis targeting the 16S rRNA gene. Three study sites were set in the forest area devoid of fire damage (cont... | ['Bacteria', 'Biodiversity', 'DNA, Bacterial', 'DNA, Ribosomal', 'Ecosystem', 'Fires', 'Indonesia', 'Molecular Sequence Data', 'RNA, Bacterial', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA', 'Soil Microbiology', 'Trees'] | 19,940,378 | [['B03'], ['G16.500.275.157.049', 'N06.230.124.049'], ['D13.444.308.212'], ['D13.444.308.475'], ['G16.500.275.157', 'N06.230.124'], ['N06.230.216'], ['Z01.252.145.380', 'Z01.639.580'], ['L01.453.245.667'], ['D13.444.735.473'], ['D13.444.735.686.670'], ['E05.393.760.700'], ['H01.158.273.540.274.555', 'N06.850.425.300'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Evolutionary distinctiveness of the extinct Yunnan box turtle (Cuora yunnanensis) revealed by DNA from an old museum specimen. | Cuora yunnanensis is an extinct turtle known from 12 specimens collected from Yunnan, China, before 1908. We used ancient DNA methods to sequence 1723 base pairs of mitochondrial DNA from a museum specimen of C. yunnanensis. Unlike some rare 'species' recently described from the pet trade, C. yunnanensis represents a l... | ['Animals', 'Base Sequence', 'China', 'DNA Primers', 'DNA, Mitochondrial', 'Genetic Variation', 'Likelihood Functions', 'Models, Genetic', 'Molecular Sequence Data', 'Museums', 'Phylogeny', 'Sequence Analysis, DNA', 'Species Specificity', 'Turtles'] | 15,801,584 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['Z01.252.474.164'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.283.225'], ['G05.365'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.450', 'N05.715.360.750.625.450', 'N06.850... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Humanities [K]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
Discovery of novel non-peptide inhibitors of BACE-1 using virtual high-throughput screening. | A novel series of isatin-based inhibitors of beta-secretase (BACE-1) have been identified using a virtual high-throughput screening approach. Structure-activity relationship studies revealed structural features important for inhibition. Docking studies suggest these inhibitors may bind within the BACE-1 active site thr... | ['Amyloid Precursor Protein Secretases', 'Catalytic Domain', 'Combinatorial Chemistry Techniques', 'Computational Biology', 'Crystallography, X-Ray', 'Drug Discovery', 'Enzyme Inhibitors', 'Hydrogen Bonding', 'Isatin', 'Models, Molecular', 'Molecular Structure', 'Stereoisomerism', 'Structure-Activity Relationship'] | 19,854,048 | [['D08.811.277.656.300.032'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['E05.197.312', 'J01.897.836.249.249'], ['H01.158.273.180', 'L01.313.124'], ['E05.196.309.742.225'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['D27.505.519.389'], ['G02.282'], ['D03.633.100.473.525'], ['E05.599.595']... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Design, implementation, and evaluation of an educational program for a new practice model. | Redesigning patient care delivery is vital to the quality of care delivered and has resulted in the development of new nursing practice models that use some form of "nurse extender." In this article, the authors describe the design, implementation, and evaluation of an educational program for a new nursing practice mod... | ['Curriculum', 'Humans', 'Inservice Training', 'Models, Nursing', 'Nursing Assistants', 'Nursing, Team', 'Program Development', 'Program Evaluation'] | 7,643,228 | [['I02.158'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.574'], ['E05.599.645'], ['M01.526.485.067.652', 'N02.360.067.652'], ['N04.590.715.571'], ['N04.452.760'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Inhibitory effects of interleukin-1 blockers on corneal fibroblast proliferation. | The regulation of would healing is one of the most important fields of research in ophthalmology today. Rabbit corneal fibroblast cultures were used to study the effects of interleukin-1 (IL-1) blockers on the proliferation of fibroblasts which is closely related to the wound healing. It was found that IL-1 blockers, s... | ['Acridines', 'Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Cell Division', 'Cells, Cultured', 'Cornea', 'DNA', 'Fibroblasts', 'Imines', 'Interleukin-1', 'Pyridazines', 'RNA', 'Rabbits', 'Thiazines'] | 8,773,933 | [['D03.633.300.046'], ['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['A09.371.060.217'], ['D13.444.308'], ['A11.329.228'], ['D02.491'], ['D12.644.276.374.465.010', 'D12.644.276.374.50... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Function of interleukin-17 and -35 in the blood of patients with hepatitis B-related liver cirrhosis. | Intrahepatic T helper (Th)17 cytokine and serum interleukin (IL)-17 levels in patients with hepatitis B are positively correlated with the progression of liver cirrhosis (LC). IL-35 can significantly inhibit the differentiation of Th17 cells and the synthesis of IL-17. The present study aimed to investigate the functio... | ['Adult', 'Female', 'Forkhead Transcription Factors', 'Gene Expression', 'Gene Expression Profiling', 'Hepatitis B', 'Hepatitis B, Chronic', 'Humans', 'Interleukin-17', 'Interleukins', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Minor Histocompatibility Antigens', 'Protein Binding'] | 25,323,532 | [['M01.060.116'], ['D12.776.260.950.249', 'D12.776.930.977.249'], ['G05.297'], ['E05.393.332'], ['C01.221.250.500', 'C01.925.256.430.400', 'C01.925.440.435', 'C06.552.380.705.437'], ['C01.221.250.500.100', 'C01.925.256.430.400.100', 'C01.925.440.435.100', 'C06.552.380.350.100', 'C06.552.380.705.437.100'], ['B01.050.150... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Profile of acute kidney injury after open heart surgeries in a tertiary care hospital. | Our objective is to determine the incidence, etiology, risk factors and outcome of acute kidney injury (AKI) after open heart surgery. A prospective study was conducted on 62 patients who underwent open heart surgery and were followed-up for the development of AKI and to determine its incidence, etiology and outcome. P... | ['Acute Kidney Injury', 'Adolescent', 'Adult', 'Cardiac Surgical Procedures', 'Child', 'Child, Preschool', 'Diabetic Nephropathies', 'Female', 'Gout', 'Humans', 'Hypertension', 'Incidence', 'Male', 'Middle Aged', 'Operative Time', 'Postoperative Complications', 'Prospective Studies', 'Risk Factors', 'Tertiary Care Cent... | 26,586,056 | [['C12.777.419.780.050', 'C13.351.968.419.780.050'], ['M01.060.057'], ['M01.060.116'], ['E04.100.376', 'E04.928.220'], ['M01.060.406'], ['M01.060.406.448'], ['C12.777.419.192', 'C13.351.968.419.192', 'C19.246.099.875'], ['C05.550.114.423', 'C05.550.354.500', 'C05.799.414', 'C16.320.565.798.368', 'C18.452.648.798.368'],... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Folinic Acid Increases Protein Arginine Methylation in Human Endothelial Cells. | Elevated plasma total homocysteine (tHcy) is associated with increased risk of cardiovascular disease, but the mechanisms underlying this association are not completely understood. Cellular hypomethylation has been suggested to be a key pathophysiologic mechanism, since S-adenosylhomocysteine (AdoHcy), the Hcy metaboli... | ['Arginine', 'Cells, Cultured', 'Dose-Response Relationship, Drug', 'Homocysteine', 'Human Umbilical Vein Endothelial Cells', 'Humans', 'Leucovorin', 'Methionine', 'Methylation', 'Protein Processing, Post-Translational', 'S-Adenosylhomocysteine'] | 29,587,354 | [['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['A11.251'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.886.030.498', 'D12.125.166.498'], ['A11.436.275.682'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.733.631.400.800.350.450', 'D08.211.840.300.500'], ['D02.886.030.676', 'D12.125.142.... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tissue-limited mosaicism in Pallister-Killian syndrome -- a case in point. | We report a case of Pallister-Killian syndrome in a term female infant. Antenatal ultrasound showed left diaphragmatic hernia and polyhydramnios. She was ventilated from birth and the diaphragm defect repaired on day 5. She had dysmorphic features, including median cleft palate, patchy frontotemporal alopecia, hypopigm... | ['Abnormalities, Multiple', 'Cells, Cultured', 'Chromosomes, Human, Pair 12', 'Cleft Palate', 'Developmental Disabilities', 'Female', 'Fibroblasts', 'Hernia, Diaphragmatic', 'Hernias, Diaphragmatic, Congenital', 'Humans', 'In Situ Hybridization, Fluorescence', 'Infant, Newborn', 'Intellectual Disability', 'Karyotyping'... | 12,082,482 | [['C16.131.077'], ['A11.251'], ['A11.284.187.520.300.325.360', 'G05.360.162.520.300.325.360'], ['C05.500.460.185', 'C05.660.207.540.460.185', 'C07.320.440.185', 'C07.465.525.185', 'C07.650.500.460.185', 'C07.650.525.185', 'C16.131.621.207.540.460.185', 'C16.131.850.500.460.185', 'C16.131.850.525.185'], ['F03.625.421'],... | ['Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Localization of the gene for the erythroid anion exchange protein, band 3 (EMPB3), to human chromosome 17. | We have isolated genomic DNA clones which code for the human erythroid membrane protein band 3 (EMPB3). The identification of the gene has been confirmed by comparison of the amino acid sequence derived from the nucleotide sequence for two restriction fragments from the 5' end of the gene. Two exons have been identifie... | ['Amino Acid Sequence', 'Animals', 'Anion Exchange Protein 1, Erythrocyte', 'Base Sequence', 'Chromosome Mapping', 'Chromosomes, Human, Pair 17', 'DNA', 'Exons', 'Genetic Markers', 'Humans', 'Hybrid Cells', 'Mice', 'Molecular Sequence Data'] | 3,478,298 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.157.530.450.162.193.500', 'D12.776.157.530.450.437.249.500', 'D12.776.157.530.937.656.249.500', 'D12.776.543.550.190.276.500', 'D12.776.543.550.779.249.500', 'D12.776.543.585.450.162.193.500', 'D12.776.543.585.450.437.249.500', 'D12.776.543.585.937.776... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Clonality and recombination in the life history of an asexual arbuscular mycorrhizal fungus. | Arbuscular mycorrhizal (AM) fungi in the phylum Glomeromycota colonize roots of the majority of land plants and assist them in the uptake of mineral nutrients in exchange for plant-assimilated carbon. In the absence of sexual reproductive structures and with asexual spore morphology conserved since the Ordovician, Glom... | ['Base Sequence', 'Clone Cells', 'Cluster Analysis', 'Ecosystem', 'Genes, Fungal', 'Genetics, Population', 'Geography', 'Glomeromycota', 'Haplotypes', 'Molecular Sequence Data', 'Mutation', 'Mycorrhizae', 'Phylogeny', 'Population Dynamics', 'Recombination, Genetic', 'Reproduction, Asexual'] | 20,566,475 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.353'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['G16.500.275.157', 'N06.230.124'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['H01.158.273.343.335'], ['H01.277.500'], ['B01.300.3... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
The C-terminus of the thromboxane receptor contributes to coupling and desensitization in a mouse mesangial cell line. | To investigate regulatory domains of the thromboxane A2 (TxA2) receptor, we constructed a truncated form of the mouse TxA2 receptor and expressed it in a mesangial cell line. The mutant receptor lacked 22 amino acids in the C-terminus including four potential phosphorylation sites. Ligand binding of mutant receptors wa... | ['Amino Acid Sequence', 'Animals', 'Calcium', 'Cell Line', 'Glomerular Mesangium', 'Indoles', 'Maleimides', 'Mice', 'Molecular Sequence Data', 'Phorbol 12,13-Dibutyrate', 'Protein Kinase C', 'Receptors, Thromboxane', 'Structure-Activity Relationship'] | 9,336,326 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251.210'], ['A05.810.453.324.359.620.500', 'A05.810.453.736.520.620.500'], ['D03.633.100.473'], ['D02.241.081.337.502.524', 'D02.478.440', 'D03.383.129.578.399'], ['B01.050.150.900.649.313.992.635.505.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The effect of lactose supplementation and source on feed intake and production characteristics of laying hens. | Three experiments involving a total of 550 laying hens were conducted to study the effects of low level lactose feeding on the egg production characteristics of laying hens. The specific purposes were to determine if lactose influenced calcium utilization and feed intake and if there were any important interactions bet... | ['Animals', 'Calcium, Dietary', 'Chickens', 'Dietary Carbohydrates', 'Eating', 'Egg Shell', 'Female', 'Lactose', 'Milk', 'Oviposition'] | 6,984,508 | [['B01.050'], ['D01.146.395'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D09.301', 'G07.203.300.362', 'J02.500.362'], ['G07.203.650.283', 'G10.261.330'], ['A13.316'], ['D09.698.629.305.340', 'D09.947.750.340'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Comparative efficacies of azithromycin and ciprofloxacin against experimental Salmonella typhimurium infection in mice. | Azithromycin was compared with ciprofloxacin for the treatment of established intracellular infection with Salmonella typhimurium LT-2 in CF-1 mice. For studies of mortality, mice received five times the LD50 of organisms intraperitoneally and were given drugs intragastrically once daily for seven days. For studies of ... | ['Animals', 'Azithromycin', 'Ciprofloxacin', 'Colony Count, Microbial', 'Erythromycin', 'Female', 'Mice', 'Microbial Sensitivity Tests', 'Salmonella Infections, Animal', 'Salmonella typhimurium', 'Spleen'] | 8,385,094 | [['B01.050'], ['D02.540.576.500.992.050'], ['D03.633.100.810.835.322.186'], ['E01.370.225.875.220', 'E05.200.875.220'], ['D02.540.576.500.992'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['C01.150.252.400.310.821.706', 'C22.812'], ['B03.440.450.425.800.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Foetal fibroblasts introduced to cleaving mouse embryos contribute to full-term development. | Foetal fibroblasts (FFs) labelled with vital fluorescent dye were microsurgically introduced into eight-cell mouse embryos, three cells to each embryo. FFs were first identified in the inner cell mass (ICM) in about one-third of embryos, whereas in three quarters of embryos FFs were located among trophoblast cells. Som... | ['Animals', 'Biomarkers', 'Blastocyst Inner Cell Mass', 'Cell Differentiation', 'Cell Proliferation', 'Chimera', 'Cleavage Stage, Ovum', 'Fetal Development', 'Fibroblasts', 'Glucose-6-Phosphate Isomerase', 'Isoenzymes', 'Mice', 'Microscopy, Fluorescence', 'Trophoblasts'] | 17,244,747 | [['B01.050'], ['D23.101'], ['A16.254.500.533'], ['G04.152'], ['G04.161.750', 'G07.345.249.410.750'], ['B05.200'], ['A16.166'], ['G07.345.500.325.235', 'G08.686.784.170.157'], ['A11.329.228'], ['D08.811.399.475.200.350'], ['D08.811.348', 'D12.776.800.300'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.350.515.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib. | HSP90 inhibition represents a promising route to cancer therapy, taking advantage of cancer cell-inherent proteotoxic stress. The HSP90-inhibitor ganetespib showed benefit in advanced clinical trials. This raises the need to identify the molecular determinants of treatment response. We tested the efficacy of ganetespib... | ['Antineoplastic Agents', 'Apoptosis', 'Cell Line, Tumor', 'Colorectal Neoplasms', 'Glucuronosyltransferase', 'HSP90 Heat-Shock Proteins', 'Humans', 'Triazoles'] | 25,210,794 | [['D27.505.954.248'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['D08.811.913.400.450.480'], ['D12.776.580.216.380'], ['B01.050.150.900.649.313.988.400.112.4... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Exercise training in heart failure]. | Exercise training in patients with chronic stable heart failure (HF) is a recommended and broadly accepted treatment strategy that is an integral part of an evidence-based management involving pharmacological and non-pharmacological therapies. There is ample scientific evidence that exercise training in HF with reduced... | ['Chronic Disease', 'Evidence-Based Medicine', 'Exercise Therapy', 'Heart Failure', 'Humans', 'Physical Conditioning, Human', 'Quality of Life'] | 24,817,538 | [['C23.550.291.500'], ['H02.249.750', 'H02.403.200.400'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.410.698.277.311', 'I03.350.311'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837']] | ['Diseases [C]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
An Unusual Variant of Hepatic Inflammatory Angiomyolipoma: Report of a Rare Entity. | Hepatic angiomyolipoma is a rare mesenchymal tumor with a broad spectrum of histological appearance. A 44-year-old female presented with abdominal discomfort. MRI revealed a 3.6 cm well-defined hepatic lesion. Ultrasound-guided core biopsy with imprint smears was performed. The smears showed histiocytes with a few epit... | ['Adult', 'Angiomyolipoma', 'Epithelioid Cells', 'Female', 'Histiocytes', 'Humans', 'Immunohistochemistry', 'Inflammation', 'Liver', 'Liver Neoplasms'] | 26,927,347 | [['M01.060.116'], ['C04.557.450.550.125', 'C04.557.450.692.249'], ['A11.329.372.300', 'A11.627.482.300', 'A11.733.397.300', 'A15.382.670.522.300', 'A15.382.680.397.300'], ['A11.329.372.385', 'A11.627.482.385', 'A11.733.397.385', 'A15.382.670.522.385', 'A15.382.680.397.385'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
External validation of the platelet count/spleen diameter ratio for the diagnosis of esophageal varices in hepatitis C virus-related cirrhosis. | BACKGROUND: Screening for esophageal varices (EV) is an important part of the diagnostic workup of cirrhotic patients.AIMS: To independently validate the use of the platelet count/spleen diameter ratio for the non-invasive diagnosis of EV in patients with HCV-related cirrhosis and in a sub-group of patients with compen... | ['Adult', 'Aged', 'Esophageal and Gastric Varices', 'Female', 'Hepatitis C', 'Humans', 'Liver Cirrhosis', 'Male', 'Middle Aged', 'Organ Size', 'Platelet Count', 'Prospective Studies', 'Spleen'] | 18,594,972 | [['M01.060.116'], ['M01.060.116.100'], ['C06.405.117.240', 'C06.552.494.414'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.355.412'], ['M01.060.116.630'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Extraosseous Ewing sarcoma of the thyroid gland. | Ewing sarcoma of the bone is a highly malignant round-cell tumor that typically presents between 10 to 20 years of age and is more common in boys. It can have an extraosseous origin, although it is rare. We report a case of extraosseous Ewing sarcoma in the thyroid gland in a 9-year-old girl. | ['Bone Neoplasms', 'Child', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Sarcoma, Ewing', 'Thyroid Neoplasms', 'Tomography, X-Ray Computed', 'Ultrasonography'] | 19,690,849 | [['C04.588.149', 'C05.116.231'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C04.557.450.565.575.650.800', 'C04.557.450.795.620.800'], ['C04.588.322.894', 'C04.588.443.915', 'C19.344.894', 'C19.874.788'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.35... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Molecular cloning of a new class of cartilage-specific matrix, chondromodulin-I, which stimulates growth of cultured chondrocytes. | Here we report the structure and bioactivity of 25 kDa glycoprotein (chondromodulin-I) as a tissue-specific functional matrix component identified and cloned for the first time. Chondromodulin-I purified from fetal bovine cartilage markedly stimulated DNA synthesis of cultured growth-plate chondrocytes in the presence ... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Blotting, Northern', 'Cattle', 'Cell Division', 'Cells, Cultured', 'Cloning, Molecular', 'DNA Replication', 'Female', 'Fetus', 'Gene Library', 'Growth Plate', 'Growth Substances', 'Guinea Pigs', 'Intercellular Signaling Peptides and Proteins', 'Male', 'Molecular Sequ... | 1,709,014 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['B01.050.150.900.649.313.500.380.271'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['E05.393.220'], ['G... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Treatment of eosinophilic meningitis with a combination of albendazole and corticosteroid. | To study the efficacy of the combination of albendazole and prednisolone for the treatment of eosinophilic meningitis, we conducted a pilot study among Thai patients with eosinophilic meningitis. Patients were given a 2-week course of prednisolone, 60 mg/day and albendazole, 15 mg/kg/ day. The primary observation param... | ['Administration, Oral', 'Adolescent', 'Adult', 'Albendazole', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Drug Therapy, Combination', 'Eosinophilia', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Meningitis, Aseptic', 'Middle Aged', 'Prednisolone', 'Prospective Studies', 'Risk Assessment',... | 15,272,765 | [['E02.319.267.100'], ['M01.060.057'], ['M01.060.116'], ['D02.241.081.251.022', 'D03.633.100.103.070'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['E02.319.310'], ['C15.378.553.231'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Bone morphogenetic protein-mediated interaction of periosteum and diaphysis. Citric acid and other factors influencing the generation of parosteal bone. | In rabbits, after long-bone growth is complete and the cambium layer regresses, mesenchymal-type cells with embryonic potential (competence) for bone development persist in the adventitial layer of periosteum. These cells are not determined osteoprogenitor cells (stem cells) because bone tissue differentiation does not... | ['Animals', 'Antacids', 'Bone Development', 'Bone Morphogenetic Proteins', 'Cartilage', 'Citrates', 'Citric Acid', 'Edetic Acid', 'Growth Substances', 'Hyaluronic Acid', 'Periosteum', 'Proteins', 'Rabbits'] | 2,118,436 | [['B01.050'], ['D27.505.519.170', 'D27.505.954.483.080'], ['G07.345.500.325.377.625.050.500', 'G11.427.578.050.500'], ['D12.644.276.954.200', 'D12.776.467.942.200', 'D23.529.942.200'], ['A02.165', 'A10.165.382'], ['D02.241.081.901.434'], ['D02.241.081.901.434.249'], ['D02.092.782.258.368.250', 'D02.241.081.018.253'], [... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of clenbuterol on histamine-induced airway obstruction in ponies. | We determined the effect of IV administered beta 2-adrenergic receptor agonist clenbuterol on pulmonary function and on the response to histamine in 12 healthy ponies. Measurements were made at base line and after saline solution or clenbuterol was administered IV at a dosage of 0.2, 0.8, or 1.6 micrograms/kg. The dosa... | ['Airway Obstruction', 'Animals', 'Clenbuterol', 'Dose-Response Relationship, Drug', 'Ethanolamines', 'Female', 'Histamine', 'Horse Diseases', 'Horses', 'Male'] | 3,565,899 | [['C08.618.846.185'], ['B01.050'], ['D02.033.100.291.231', 'D02.092.063.291.231'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.033.100.291', 'D02.033.375.291', 'D02.092.063.291'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['C22.488'], ['B01.050.150.900.649.313.984.235.472']... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
SPR biosensing coupled to a digital microfluidic microstreaming system. | This article reports on a proof-of-concept system composed of a droplet based surface plasmon resonance (SPR) system coupled to a surface acoustic wave (SAW) microfluidic plateform. It is now well established that surface based binding analyses such as SPR are highly influenced by the transport of analyte to the sensin... | ['Biosensing Techniques', 'Microfluidics', 'Streptavidin', 'Surface Plasmon Resonance'] | 17,884,436 | [['E05.601.043'], ['E05.830.666', 'H01.671.808.500', 'J01.897.520.500.500'], ['D12.776.097.835'], ['E05.196.890', 'E05.601.043.700']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Multiple traumatic brain injury and concussive symptoms among deployed military personnel. | OBJECTIVE: To identify if concussive symptoms occur with greater frequency among military personnel with multiple lifetime TBIs and if a history of TBI increases risk for subsequent TBI.PATIENTS: One hundred and sixty-one military personnel referred to a TBI clinic for evaluation and treatment of suspected head injury ... | ['Adult', 'Brain Concussion', 'Brain Injuries', 'Depression', 'Female', 'Humans', 'Incidence', 'Iraq War, 2003-2011', 'Logistic Models', 'Male', 'Military Personnel', 'Physical Examination', 'Self Report', 'Stress Disorders, Post-Traumatic', 'Time Factors', 'Trauma Severity Indices', 'United States'] | 24,070,144 | [['M01.060.116'], ['C10.228.140.199.444.250', 'C10.900.300.087.235.250', 'C10.900.300.350.300', 'C26.915.300.200.194.250', 'C26.915.300.450.500', 'C26.974.382.200'], ['C10.228.140.199', 'C10.900.300.087', 'C26.915.300.200'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Sedative effect of oral diazepam and chloral hydrate in the dental treatment of children. | PURPOSE: The purpose was to evaluate two sedation protocols during dental sessions in anxious children.MATERIALS AND METHODS: It was a randomized and double-blind study, with each individual being his/her own control within each protocol. Furthermore, the two protocols were compared. Twenty children (36 to 84 months ol... | ['Administration, Oral', 'Age Factors', 'Anesthesia, Dental', 'Anesthesia, Local', 'Child', 'Child Behavior', 'Child, Preschool', 'Chloral Hydrate', 'Cooperative Behavior', 'Crying', 'Dental Anxiety', 'Dental Care for Children', 'Dental Cavity Preparation', 'Dental Restoration, Permanent', 'Diazepam', 'Double-Blind Met... | 17,660,640 | [['E02.319.267.100'], ['N05.715.350.075', 'N06.850.490.250'], ['E03.155.141', 'E06.045'], ['E03.155.086.231'], ['M01.060.406'], ['F01.145.179'], ['M01.060.406.448'], ['D02.033.455.250.130'], ['F01.145.813.115'], ['F01.145.209.530.258', 'F01.525.200.310.300'], ['F01.470.132.300'], ['E06.170.152', 'N02.421.240.190.215'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
New Acridine Thiourea Gold(I) Anticancer Agents: Targeting the Nucleus and Inhibiting Vasculogenic Mimicry. | Two new 1-acridin-9-yl-3-methylthiourea Au(I) DNA intercalators [Au(ACRTU)2]Cl (2) and [Au(ACRTU) (PPh3)]PF6 (3) have been prepared. Both complexes were highly active in the human ovarian carcinoma cisplatin-sensitive A2780 cell line, exhibiting IC50 values in the submicromolar range. Compounds 2 and 3 are also cytotox... | ['Acridines', 'Angiogenesis Inhibitors', 'Antineoplastic Agents', 'Cell Line, Tumor', 'Cell Nucleus', 'Gold', 'Humans', 'Intercalating Agents', 'Molecular Mimicry', 'Neoplasm Invasiveness', 'Neovascularization, Pathologic', 'Thiourea'] | 28,388,047 | [['D03.633.300.046'], ['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of a single Silastic contraceptive implant containing nomegestrol acetate (Uniplant) on endometrial morphology and ovarian function for 1 year. | PURPOSE: This study was undertaken to evaluate the effects of a subdermal implant containing nomegestrol acetate (Uniplant) on endometrial histology and ovarian function.METHODS: Twenty healthy female volunteers of reproductive age were included and completed a menstrual diary throughout the study. Hysteroscopy, transv... | ['Adolescent', 'Adult', 'Dimethylpolysiloxanes', 'Drug Implants', 'Endometrium', 'Female', 'Humans', 'Hysteroscopy', 'Megestrol', 'Menstrual Cycle', 'Norpregnadienes', 'Ovarian Follicle', 'Progesterone Congeners', 'Silicones', 'Ultrasonography'] | 17,157,108 | [['M01.060.057'], ['M01.060.116'], ['D02.756.650.700.150', 'D05.750.900.850.150', 'D25.720.900.850.150', 'J01.637.051.720.900.850.150'], ['D26.255.210.315'], ['A05.360.319.679.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.378.330', 'E01.370.388.250.360', 'E04.502.250.360', 'E04.520.360', 'E04.950.30... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
The enthesopathic changes of hypophosphatemic osteomalacia in adults: radiologic findings. | The enthesopathy (bone proliferation at sites of ligament, tendon, joint capsule, and interosseous membrane attachment) that may be present in adults who have longstanding hypophosphatemic osteomalacia, the most common type of osteomalacia, has received little attention in the radiologic literature. These proliferative... | ['Adolescent', 'Adult', 'Arthrography', 'Female', 'Humans', 'Ligaments', 'Male', 'Middle Aged', 'Muscles', 'Ossification, Heterotopic', 'Osteomalacia', 'Phosphates', 'Spine'] | 2,505,496 | [['M01.060.057'], ['M01.060.116'], ['E01.370.350.700.070'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.513', 'A10.165.669'], ['M01.060.116.630'], ['A02.633', 'A10.690'], ['C23.550.751'], ['C05.116.198.816.640', 'C18.452.104.816.640', 'C18.452.174.845.640', 'C18.654.521.500.133.770.734.640'], ['D01.029.260.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly. | The HIV-1 capsid is involved in all infectious steps from reverse transcription to integration site selection, and is the target of multiple host cell and pharmacologic ligands. However, structural studies have been limited to capsid monomers (CA), and the mechanistic basis for how these ligands influence infection is ... | ['Anti-HIV Agents', 'Binding Sites', 'Capsid', 'Capsid Proteins', 'HIV Infections', 'HIV-1', 'Humans', 'Indoles', 'Ligands', 'Models, Molecular', 'Models, Structural', 'Mutation', 'Nuclear Pore Complex Proteins', 'Phenylalanine', 'Polycyclic Compounds', 'Polymerization', 'Protein Binding', 'Protein Structure, Tertiary'... | 25,356,722 | [['D27.505.954.122.388.077.088'], ['G02.111.570.120'], ['A21.249.500.250'], ['D12.776.964.970.600.550'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Long-term progress in reading abilities in hearing-impaired children trained by the Kanazawa method. | The speech and language training for deaf children at our clinic is done by the Kanazawa method, consisting of reception and production training in sign language (SL) along with auditory/oral language (OL), and written language (WL) training. The present investigation was undertaken to explore long-term progress in rea... | ['Adolescent', 'Child', 'Deafness', 'Female', 'Humans', 'Male', 'Reading', 'Severity of Illness Index', 'Sign Language', 'Speech Perception', 'Speech Therapy'] | 8,809,322 | [['M01.060.057'], ['M01.060.406'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.559.423.557'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', 'N06.850.520.308.980.438.475.364.500'], ['E02.760.169.063... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Species differences in methaemoglobin production after addition of 4-dimethylaminophenol, a cyanide antidote, to blood in vitro: a comparative study. | Methaemoglobin production after addition of DMAP to blood of various species, has been studied in vitro. The study was undertaken both with blood, as taken, and after equilibration with atmospheric oxygen. Considerable interspecies variation in methaemoglobin production was found. When the initial rate of methaemoglobi... | ['Aminophenols', 'Animals', 'Callitrichinae', 'Cyanides', 'Geese', 'Guinea Pigs', 'Humans', 'In Vitro Techniques', 'Kinetics', 'Methemoglobin', 'Methemoglobinemia', 'Rabbits', 'Species Specificity'] | 3,103,975 | [['D02.092.146.100', 'D02.455.426.559.389.657.050'], ['B01.050'], ['B01.050.150.900.649.313.988.400.600.150.150'], ['D01.248.497.158.291', 'D01.625.400.100'], ['B01.050.150.900.248.050.350', 'B01.050.150.900.248.690.492'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481']... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Membrane bioreactor technology: a novel approach to the treatment of compost leachate. | Compost leachate forms during the composting process of organic material. It is rich in oxidizable organics, ammonia and metals, which pose a risk to the environment if released without proper treatment. An innovative method based on the membrane bioreactor (MBR) technology was developed to treat compost leachate over ... | ['Biological Oxygen Demand Analysis', 'Bioreactors', 'Caffeine', 'Electric Conductivity', 'Heterotrophic Processes', 'Hydrogen-Ion Concentration', 'Membranes, Artificial', 'Metals', 'Nitrogen Compounds', 'Oxygen', 'Soil', 'Waste Disposal, Fluid', 'Water Pollutants, Chemical'] | 23,791,422 | [['N06.850.460.350.080.500', 'N06.850.780.375.349'], ['E07.115', 'J01.897.120.115'], ['D03.132.960.175', 'D03.633.100.759.758.824.175'], ['G01.358.500.249.277'], ['G02.111.375', 'G03.393'], ['G02.300'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['D01.552'], ['D01.625'], ['D01.268.185.550', 'D01.362.670'], ['D2... | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Online learning from input versus offline memory evolution in adult word learning: effects of neighborhood density and phonologically related practice. | PURPOSE: In this study, the authors investigated adult word learning to determine how neighborhood density and practice across phonologically related training sets influence online learning from input during training versus offline memory evolution during no-training gaps.METHOD: Sixty-one adults were randomly assigned... | ['Acoustic Stimulation', 'Adolescent', 'Adult', 'Female', 'Humans', 'Language Tests', 'Male', 'Memory', 'Memory Consolidation', 'Phonetics', 'Verbal Learning', 'Vocabulary', 'Young Adult'] | 24,686,841 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.513.240'], ['F02.463.425.540'], ['F02.463.425.540.305.500'], ['L01.559.598.518'], ['F02.463.425.952'], ['L01.559.598.901'], ['M01.060.116.815']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Symptom clusters in acute myocardial infarction: a secondary data analysis. | BACKGROUND: Early recognition of acute myocardial infarction (AMI) symptoms and reduced time to treatment may reduce morbidity and mortality. People having AMI experience a constellation of symptoms, but the common constellations or clusters of symptoms have yet to be identified.OBJECTIVES: To identify clusters of symp... | ['Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Cluster Analysis', 'Cross-Sectional Studies', 'Dyspnea', 'Early Diagnosis', 'England', 'Female', 'Humans', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Nausea', 'Pain', 'Patient Acceptance of Health Care', 'Predictive Value of Tests', 'Risk Assessment', 'R... | 17,356,437 | [['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['C08.618.326', 'C23.888.852.371'], ['E01.390'], ['Z01.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Plasma and erythrocyte cholinesterase values for the common long-nosed armadillo, Dasypus novemcinctus. | Plasma and erythrocyte cholinesterase activities were determined for 40 free-living and 12 captive common long-nosed armadillos (Dasypus novemcinctus) in order to establish normal values for monitoring pesticide exposure. Plasma cholinesterase activity ranged from 105 to 549 U/liter with no sexual or seasonal differenc... | ['Animals', 'Armadillos', 'Cholinesterases', 'Cingulata', 'Erythrocytes', 'Female', 'Male', 'Organophosphorus Compounds', 'Reference Values', 'Seasons'] | 2,761,009 | [['B01.050'], ['B01.050.150.900.649.313.999.200'], ['D08.811.277.352.100.170'], ['B01.050.150.900.649.313.999'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D02.705'], ['E05.978.810'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Characterization of LuxI/LuxR and their regulation involved in biofilm formation and stress resistance in fish spoilers Pseudomonas fluorescens. | Quorum sensing (QS) is crucial for adaption and development of foodborne bacteria in diverse environments. Pseudomonas fluorescens PF07 with QS mediated acylated homoserine lactones (AHLs) activity was isolated from spoiled large yellow croaker (Pseudosciaena crocea). In this study AHL-mediated QS system was characteri... | ['4-Butyrolactone', 'Animals', 'Bacterial Proteins', 'Biofilms', 'Fishes', 'Gene Expression Regulation, Bacterial', 'Pseudomonas fluorescens', 'Repressor Proteins', 'Seafood', 'Sequence Deletion', 'Stress, Physiological', 'Trans-Activators', 'Transcription Factors'] | 30,884,254 | [['D02.540.150', 'D03.383.312.150'], ['B01.050'], ['D12.776.097'], ['A20.593', 'G06.120'], ['B01.050.150.900.493'], ['G05.308.300'], ['B03.440.400.425.625.625.325', 'B03.660.250.580.590.210'], ['D12.776.260.703', 'D12.776.930.780'], ['G07.203.300.600.875', 'J02.500.600.875'], ['G05.365.590.762', 'G05.558.800'], ['G07.7... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Outcome in infants born to mothers with unexplained elevations of maternal serum alpha-fetoprotein. | The outcome in infants without fetal neural tube defect born to mothers with elevated maternal serum alpha-fetoprotein was studied. Elevated maternal serum alpha-fetoprotein with normal amniotic fluid alpha-fetoprotein was found to be associated with an increased incidence of intrauterine growth retardation and nonneur... | ['Adult', 'Birth Weight', 'Congenital Abnormalities', 'Delivery, Obstetric', 'Female', 'Gestational Age', 'Humans', 'Infant, Newborn', 'Obstetric Labor Complications', 'Pregnancy', 'Prospective Studies', 'Retrospective Studies', 'alpha-Fetoproteins'] | 2,421,232 | [['M01.060.116'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['C16.131'], ['E04.520.252'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C13.703.420'], ['G0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mass spectrometry in newborn and metabolic screening: historical perspective and future directions. | The growth of mass spectrometry (MS) in clinical chemistry has primarily occurred in two areas: the traditional clinical chemistry areas of toxicology and therapeutic drug monitoring and more recent, human genetics and metabolism, specifically inherited disorders of intermediary metabolism and newborn screening. Capill... | ['Blood Chemical Analysis', 'History, 20th Century', 'Humans', 'Infant, Newborn', 'Mass Spectrometry', 'Metabolic Diseases', 'Neonatal Screening'] | 19,034,889 | [['E01.370.225.124.100', 'E05.200.124.100'], ['K01.400.504.968'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E05.196.566'], ['C18.452'], ['E01.370.225.910', 'E01.370.500.580', 'E05.200.910', 'E05.318.308.980.438.580.580', 'N02.421.726.233.443.816', 'N05.715.360.300.800.438.500.575', 'N06.85... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Cloning and kinetics of expression of Brucella abortus heat shock proteins by baculovirus recombinants. | In an effort to develop genetically engineered Brucella abortus (BA) vaccines, the genes encoding heat shock proteins (HSPs) GroEL, GroES, and HtrA were cloned and expressed in the BAC-TO-BAC Baculovirus System, and the kinetics of protein expression were analyzed using various insect cell lines in suspension cultures,... | ['Animals', 'Antibodies, Monoclonal', 'Bacterial Proteins', 'Bacterial Vaccines', 'Blotting, Southern', 'Blotting, Western', 'Brucella abortus', 'Brucellosis, Bovine', 'Cattle', 'Cell Line', 'Chaperonin 10', 'Chaperonin 60', 'Cloning, Molecular', 'Electrophoresis, Polyacrylamide Gel', 'Female', 'Heat-Shock Proteins', '... | 10,889,410 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.097'], ['D20.215.894.135'], ['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['B03.440.400.425... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Epidemiological analysis of the early 38 fatalities in Hubei, China, of the coronavirus disease 2019. | Background: Since the emergence of coronavirus disease 2019 (COVID-19) in Hubei province of China by the end of 2019, it has burned its way across the globe, resulting in a still fast-growing death toll that far exceeded those from severe acute respiratory syndrome (SARS) in less than two months. As there is a paucity ... | ['Age Distribution', 'Aged', 'Aged, 80 and over', 'Betacoronavirus', 'COVID-19', 'China', 'Coronavirus', 'Coronavirus Infections', 'Cough', 'Disease Outbreaks', 'Dyspnea', 'Female', 'Fever', 'Humans', 'Male', 'Middle Aged', 'Pandemics', 'Pneumonia, Viral', 'Prospective Studies', 'SARS-CoV-2', 'Sex Distribution'] | 32,373,340 | [['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B04.820.578.500.540.150.113'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['Z01.252.474.164'], ['B04.820.578... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
PKA-dependent phosphorylation of serum response factor inhibits smooth muscle-specific gene expression. | OBJECTIVE: Our goal was to identify phosphorylation sites that regulate serum response factor (SRF) activity to gain a better understanding of the signaling mechanisms that regulate SRF's involvement in smooth muscle cell (SMC)-specific and early response gene expression.METHODS AND RESULTS: By screening phosphorylatio... | ['Amino Acid Sequence', 'Amino Acid Substitution', 'Animals', 'Binding Sites', 'Cell Differentiation', 'Cells, Cultured', 'Cyclic AMP-Dependent Protein Kinases', 'Embryonic Stem Cells', 'Gene Expression', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', 'Myocytes, Smooth Muscle', 'Nuclear Proteins', 'Phosphoryl... | 19,778,940 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['G02.111.570.120'], ['G04.152'], ['A11.251'], ['D08.811.913.696.620.682.700.150.125', 'D12.644.360.200.125', 'D12.776.476.200.125'], ['A11.872.700.250'], ['G05.297'], ['L01.453.245.667'], ['E05.393.420.601.575'], ['A11.62... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Polymorphism in fowl serum albumin. VI. Changes in in vitro protein synthesizing activity in developing embryonic fowl liver. | Cell-free protein synthesizing systems were prepared from the livers of chick embryos at selected ages and the characteristics of individual fractions were compared. While polysomes showed decreasing size with older embryos, isolated polysomes did not differ significantly in amino acid incorporating activity when assay... | ['Amino Acids', 'Animals', 'Chick Embryo', 'Chickens', 'Kinetics', 'Liver', 'Polymorphism, Genetic', 'Polyribosomes', 'Protein Biosynthesis', 'RNA, Transfer', 'Ribonucleases', 'Serum Albumin'] | 460,176 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The complete human olfactory subgenome. | Olfactory receptors likely constitute the largest gene superfamily in the vertebrate genome. Here we present the nearly complete human olfactory subgenome elucidated by mining the genome draft with gene discovery algorithms. Over 900 olfactory receptor genes and pseudogenes (ORs) were identified, two-thirds of which we... | ['Chromosome Mapping', 'Databases, Factual', 'Evolution, Molecular', 'GC Rich Sequence', 'Gene Frequency', 'Genome, Human', 'Humans', 'Multigene Family', 'Phylogeny', 'Pseudogenes', 'Receptors, Odorant', 'Sequence Homology, Nucleic Acid'] | 11,337,468 | [['E05.393.183'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['G05.045.250', 'G16.075.250'], ['G02.111.570.080.380', 'G05.360.080.380'], ['G05.330'], ['G05.360.340.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.340.024.340.645'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G05.360.340.024.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Vascular Adhesion Protein-1 (VAP-1) as Predictor of Radiographic Severity in Symptomatic Knee Osteoarthritis in the New York University Cohort. | BACKGROUND: To investigate the expression of vascular adhesion protein-1 (VAP-1) in joint tissues and serum in symptomatic knee osteoarthritis (SKOA) patients and examine whether VAP-1 levels predict increased risk of disease severity in a cross-sectional study.METHODS: Baseline VAP-1 expression and soluble VAP-1 (sVAP... | ['Adult', 'Aged', 'Amine Oxidase (Copper-Containing)', 'Biomarkers', 'Cell Adhesion Molecules', 'Female', 'Humans', 'Male', 'Middle Aged', 'Osteoarthritis, Knee', 'Radiography', 'Synovial Fluid'] | 31,146,362 | [['M01.060.116'], ['M01.060.116.100'], ['D08.811.682.664.249'], ['D23.101'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.550.114.606.500', 'C05.799.613.500'], ['E01.370.350.700'], ['A02.835.583.443.800.800', 'A12.207.270.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Chronic caregiver stress and IgE expression, allergen-induced proliferation, and cytokine profiles in a birth cohort predisposed to atopy. | BACKGROUND: Psychologic stress modifies immune function and cytokine production.OBJECTIVE: We examined relationships between caregiver stress on the following markers of early childhood immune response: (1) IgE expression (n=215); (2) mitogen-induced and allergen-specific (Dermatophagoides farinae [Der f 1] and cockroa... | ['Allergens', 'Antigens, Dermatophagoides', 'Antigens, Plant', 'Arthropod Proteins', 'Caregivers', 'Chronic Disease', 'Cysteine Endopeptidases', 'Cytokines', 'Female', 'Humans', 'Hypersensitivity', 'Immunoglobulin E', 'Infant', 'Interferon-gamma', 'Logistic Models', 'Lymphocyte Activation', 'Male', 'Stress, Psychologic... | 15,208,584 | [['D23.050.063'], ['D23.050.181'], ['D23.050.291'], ['D12.776.093'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['C23.550.291.500'], ['D08.811.277.656.262.500', 'D08.811.277.656.300.200'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C20.543'], ['D12.776.... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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