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Manipulating soil microbial communities in extensive green roof substrates. | There has been very little investigation into the soil microbial community on green roofs, yet this below ground habitat is vital for ecosystem functioning. Green roofs are often harsh environments that would greatly benefit from having a healthy microbial system, allowing efficient nutrient cycling and a degree of dro... | ['Agricultural Inoculants', 'Bacteria', 'Biomass', 'Conservation of Natural Resources', 'Construction Industry', 'Ecosystem', 'Fungi', 'Soil', 'Soil Microbiology'] | 24,992,459 | [['B01.300.053', 'B03.054'], ['B03'], ['G16.500.275.157.100', 'N06.230.124.100'], ['J01.256', 'N06.230.080'], ['J01.576.655.125'], ['G16.500.275.157', 'N06.230.124'], ['B01.300'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['H01.158.273.540.274.555', 'N06.850.425.300']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Chronic Intrahippocampal Infusion of HIV-1 Neurotoxic Proteins: A Novel Mouse Model of HIV-1 Associated Inflammation and Neural Stem Cell Dysfunction. | HIV-1 infection causes chronic neuroinflammation resulting in cognitive decline associated with diminution of survival of neural stem cells (NSC). In part, this is attributable to production of toxic viral proteins (gp120 and tat) by infected cells in the brain that can activate microglia. Here, we evaluated a novel mo... | ['AIDS Dementia Complex', 'Animals', 'Disease Models, Animal', 'HIV Envelope Protein gp120', 'HIV-1', 'Hippocampus', 'Inflammation', 'Inflammation Mediators', 'Infusions, Parenteral', 'Mice', 'Mice, Inbred C57BL', 'Microglia', 'Neural Stem Cells', 'Neurogenesis', 'Random Allocation', 'Recombinant Proteins', 'Sequence A... | 30,905,008 | [['C01.221.250.875.049', 'C01.221.812.640.400.070', 'C01.778.640.400.070', 'C01.925.782.815.616.400.049', 'C01.925.813.400.070', 'C10.228.140.380.070', 'C20.673.480.070', 'F03.615.400.050'], ['B01.050'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D12.776.964.775.325.164.249', 'D12.776.964.775.562.500.500', 'D12.7... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
An origin of presumptive preneoplastic foci and nodules from hepatocytes in chemical carcinogenesis in rat liver. | The sites and times of appearance of preneoplastic foci in rat liver acinus during the first 11 days after initiation with diethylnitrosamine and promotion with 2-acetylaminofluorene plus partial hepatectomy was observed in three separate experiments. Foci appeared as alterations of hepatocytes followed by focal prolif... | ['Animals', 'Liver Neoplasms', 'Liver Neoplasms, Experimental', 'Male', 'Precancerous Conditions', 'Rats', 'Rats, Inbred F344'] | 8,062,236 | [['B01.050'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['C04.588.274.623.460', 'C04.619.540', 'C06.301.623.460', 'C06.552.697.580', 'E05.598.500.496.750'], ['C04.834'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760.200', 'B01.050.150.900.649.313.992.635.505.700.400.200']] | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Immunoreactivity studies on synthetic peptides deriving from immunodominant region of hepatitis C virus NS5a gene]. | OBJECTIVE: To identify the location of major immunodominant antigenic region and study the relationship between the gene heterogeneity and immunoreactivity via detecting antigenic reactivity of synthetic peptides deriving from immunodominant region in different genotypes of hepatitis C virus (HCV) NS5a gene.METHODS: In... | ['Amino Acid Sequence', 'Antigenic Variation', 'Antigens, Viral', 'Epitope Mapping', 'Genotype', 'Hepacivirus', 'Hepatitis C', 'Hepatitis C Antibodies', 'Humans', 'Immunodominant Epitopes', 'Peptides', 'Recombinant Proteins', 'Sequence Homology, Amino Acid', 'Viral Nonstructural Proteins'] | 15,650,785 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G05.365.073', 'G12.500.249'], ['D23.050.327'], ['E05.478.274', 'E05.601.690.300'], ['G05.380'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['D12.776.124.486.485.114.254.450.510', 'D12.776.12... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Extreme elevation of intrasellar pressure in patients with pituitary tumor apoplexy: relation to pituitary function. | The dominant mechanism for hypopituitarism and hyperprolactinemia commonly observed in patients with pituitary macroadenomas was postulated to be increased intrasellar pressure (ISP) caused by the slow and gradual expansion of adenomas within the sella turcica. Hemorrhagic infarction of adenomas (pituitary tumor apople... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Male', 'Middle Aged', 'Pituitary Apoplexy', 'Pituitary Gland', 'Pituitary Neoplasms', 'Pressure', 'Prolactin', 'Sella Turcica'] | 15,531,524 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.228.140.300.535.625', 'C10.228.140.617.738.350', 'C14.907.253.573.600', 'C19.700.725'], ['A06.300.747', 'A06.688.357.750', 'A08.186.211.180.497.352.435.500', 'A08.186.211.200.317.3... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Use of deep vein thrombosis prophylaxis in hospitalized cancer patients. | Venous thromboembolism is a common complication and a major cause of morbidity and mortality in cancer patients. Patients with malignancies have a four-fold greater risk of venous thromboembolism compared with patients without malignancies. Underuse of deep vein thrombosis (DVT) prophylaxis persists, despite guidelines... | ['Adult', 'Aged', 'Anticoagulants', 'Contraindications', 'Enoxaparin', 'Female', 'Humans', 'Inpatients', 'Male', 'Medication Errors', 'Middle Aged', 'Neoplasms', 'Premedication', 'Retrospective Studies', 'Risk Factors', 'Venous Thrombosis'] | 19,587,584 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.502.119'], ['E02.208'], ['D09.698.373.400.300.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.643.470'], ['E02.319.529', 'N02.421.450.500'], ['M01.060.116.630'], ['C04'], ['E02.319.703'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The problematical self in Kant and Kohut. | Kant and Kohut each present an earlier and a later philosophical system. Each author bases his two systems on a conception of the self which is importantly different from the earlier system to the later system. The later systems are more or less incompatible with the earlier systems but have the advantage of elegance a... | ['Ego', 'Humans', 'Philosophy', 'Psychoanalytic Theory', 'Psychoanalytic Therapy'] | 7,403,389 | [['F01.752.747.189', 'F02.739.794.206'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['K01.752'], ['F02.739.794'], ['F04.754.709']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activities of antioxidant scavenger enzymes (superoxide dismutase and glutathione peroxidase) in erythrocytes in adult women with and without type II diabetes. | It is widely believed that oxidative stress plays an important role in the pathogenesis of type II diabetes. The present study was undertaken to examine the functioning of two antioxidant scavenger enzymes, superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), in erythrocytes in a population of healthy aging ... | ['Aging', 'Diabetes Mellitus, Type 2', 'Erythrocytes', 'Female', 'Glutathione Peroxidase', 'History, 16th Century', 'History, 17th Century', 'History, 18th Century', 'Humans', 'Reference Values', 'Superoxide Dismutase'] | 15,203,888 | [['G07.345.124'], ['C18.452.394.750.149', 'C19.246.300'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D08.811.682.732.500'], ['K01.400.475.750'], ['K01.400.504.750'], ['K01.400.504.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.978.810'], ['D08.811.682.881']] | ['Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Humanities [K]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization and kinetic analysis of the intracellular domain of human protein tyrosine phosphatase beta (HPTP beta) using synthetic phosphopeptides. | The intracellular domain of human protein tyrosine phosphatase beta (HPTP beta) (44 kDa) was expressed in bacteria, purified using epitope 'tagging' immunoaffinity chromatography, and characterized with respect to kinetic profile, substrate specificity and potential modulators of enzyme activity. A chromogenic assay ba... | ['Amino Acid Sequence', 'Base Sequence', 'Coloring Agents', 'DNA Primers', 'Escherichia coli', 'Humans', 'Kinetics', 'Molecular Sequence Data', 'Phosphopeptides', 'Protein Tyrosine Phosphatases', 'Recombinant Proteins', 'Rosaniline Dyes', 'Substrate Specificity'] | 8,135,747 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D27.720.233'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
ERCC1 and XPD/ERCC2 polymorphisms' predictive value of oxaliplatin-based chemotherapies in advanced colorectal cancer has an ethnic discrepancy: a meta-analysis. | Our purpose is to evaluate the predictive value of the genetic polymorphisms of Excision repair cross-complementing group 1 (ERCC1) and xeroderma pigmentosum group D/excision repair cross-complementing group 2 (XPD/ERCC2) in patients with advanced colorectal cancer receiving oxaliplatin-based chemotherapy, and we perfo... | ['Antineoplastic Agents', 'Asian Continental Ancestry Group', 'Colorectal Neoplasms', 'DNA-Binding Proteins', 'Endonucleases', 'European Continental Ancestry Group', 'Female', 'Humans', 'Male', 'Organoplatinum Compounds', 'Oxaliplatin', 'Pharmacogenetics', 'Polymorphism, Single Nucleotide', 'Xeroderma Pigmentosum Group... | 24,833,529 | [['D27.505.954.248'], ['M01.686.508.200'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['D12.776.260'], ['D08.811.277.352.355'], ['M01.686.508.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.691.788'], ['D0... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
When friendship formation goes down the toilet: design features of shared accommodation influence interpersonal bonds and well-being. | Despite its omnipresence, the influence of the built environment on human psychology is not well understood. In a five-wave longitudinal study, we investigated whether physical design features within shared student accommodation predicted the frequency of coincidental meetings between new flatmates, and whether these m... | ['Female', 'Friends', 'Housing', 'Humans', 'Interior Design and Furnishings', 'Interpersonal Relations', 'Male', 'Object Attachment', 'Personal Satisfaction', 'Regression Analysis', 'Students', 'Surveys and Questionnaires'] | 24,697,622 | [['M01.252'], ['J03.340', 'N01.224.791.400', 'N06.230.150.360', 'N06.850.505.400.800.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.086.339.290'], ['F01.829.401'], ['F02.739.794.624'], ['F01.145.677'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['M01.848'], ['E05.318.308.980', 'N0... | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Developmental validation of a single-tube amplification of the 13 CODIS STR loci, D2S1338, D19S433, and amelogenin: the AmpFlSTR Identifiler PCR Amplification Kit. | Analysis of length polymorphism at short tandem repeat (STR) loci utilizing the polymerase chain reaction (PCR) process has proven to be an ideal assay for human identification purposes. The short length of STR loci coupled with the amplification of target sequence through PCR allows for a robust, sensitive, and specif... | ['Animals', 'Bacteria', 'Cats', 'Cattle', 'Chickens', 'DNA Fingerprinting', 'DNA Primers', 'Deoxyribonucleotides', 'Dogs', 'Genotype', 'Horses', 'Humans', 'Indicators and Reagents', 'Magnesium Chloride', 'Mice', 'Polymerase Chain Reaction', 'Polymorphism, Genetic', 'Potassium Chloride', 'Sequence Analysis, DNA', 'Speci... | 15,568,700 | [['B01.050'], ['B03'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['B01.050.150.900.649.313.500.380.271'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['E05.318.740.225.500.500', 'E05.393.290', 'I01.198.780.937.375', 'N04.452.910.099.750'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Anti-Tac(Fv)-PE40, a single chain antibody Pseudomonas fusion protein directed at interleukin 2 receptor bearing cells. | Anti-Tac(Fv)-PE40 is a chimeric single chain immunotoxin in which anti-Tac variable heavy and light chains held together by a peptide linker are attached to PE40, a truncated form of Pseudomonas exotoxin. This molecule was shown to be extremely cytotoxic for interleukin 2 (IL2) receptor bearing cells in tissue culture ... | ['ADP Ribose Transferases', 'Amino Acid Sequence', 'Animals', 'Bacterial Toxins', 'Cell Line', 'Cell Survival', 'Cloning, Molecular', 'Exotoxins', 'Genetic Vectors', 'Immunoglobulin Heavy Chains', 'Immunoglobulin Light Chains', 'Immunotoxins', 'Kinetics', 'Molecular Sequence Data', 'Polymerase Chain Reaction', 'Pseudom... | 2,118,522 | [['D08.811.913.400.725.115'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D23.946.123'], ['A11.251.210'], ['G04.346'], ['E05.393.220'], ['D23.946.350'], ['G05.360.337'], ['D12.776.124.486.485.705.500', 'D12.776.124.790.651.705.500', 'D12.776.377.715.548.705.500'], ['D12.776.124.486.485.705.750', 'D12.776... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Structure-function relationships of human liver cytochromes P450 3A: aflatoxin B1 metabolism as a probe. | Cytochromes P450 3A4 and 3A5, the dominant drug-metabolizing enzymes in the human liver, share >85% primary amino acid sequence identity yet exhibit different regioselectivity toward aflatoxin B1 (AFB1) biotransformation [Gillam et al., (1995) Arch. Biochem. Biophys. 317, 374-384]. P450 3A4 apparently prefers AFB1 3alp... | ['Aflatoxin B1', 'Amino Acid Sequence', 'Animals', 'Aryl Hydrocarbon Hydroxylases', 'Binding Sites', 'Computer Simulation', 'Cytochrome P-450 CYP3A', 'Cytochrome P-450 Enzyme System', 'Cytochromes b5', 'Humans', 'Male', 'Microsomes, Liver', 'Models, Molecular', 'Molecular Sequence Data', 'Mutagenesis, Site-Directed', '... | 9,730,826 | [['D03.383.663.283.119.075', 'D03.633.100.150.119.075', 'D23.946.587.142.075'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D08.244.453.005', 'D08.811.682.690.708.170.010', 'D12.776.422.220.453.010'], ['G02.111.570.120'], ['L01.224.160'], ['D08.244.453.860.500', 'D08.811.682.662.582.353', 'D08.811.682.69... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A case of intraductal papillary adenocarcinoma of the pancreas associated with mass forming chronic pancreatitis. | A case of intraductal papillary adenocarcinoma of the pancreas associated with mass forming chronic pancreatitis without calcifications is described. Pancreatolithiasis, or calcified pancreas, is recognized as a high risk factor for pancreatic cancer. However, epidemiologic studies have found that carcinoma of the panc... | ['Aged', 'Carcinoma, Intraductal, Noninfiltrating', 'Chronic Disease', 'Humans', 'Hyperplasia', 'Male', 'Pancreatic Ducts', 'Pancreatic Neoplasms', 'Pancreatitis', 'Precancerous Conditions'] | 1,327,319 | [['M01.060.116.100'], ['C04.557.470.200.025.275', 'C04.557.470.200.240.187.250', 'C04.557.470.615.275'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['A03.734.667'], ['C04.588.274.761', 'C04.588.322.475', 'C06.301.761', 'C06.689.667', 'C19.344.421'], ['C06.689.750'], ['C04.834... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The effect of inhaled nitric oxide on the course of extracorporeal membrane oxygenation and the occurrence of hemorrhagic complications. | This study evaluated the relation between prior inhaled nitric oxide (iNO) and the time to initiation and duration of treatment with veno-arterial extracorporeal membrane oxygenation (ECMO) and the occurrence of hemorrhagic complications. A retrospective study was conducted in 59 human newborns treated for respiratory ... | ['Administration, Inhalation', 'Bronchodilator Agents', 'Cerebral Hemorrhage', 'Extracorporeal Membrane Oxygenation', 'Humans', 'Infant, Newborn', 'Infant, Premature, Diseases', 'Nitric Oxide', 'Respiratory Insufficiency', 'Retrospective Studies'] | 19,293,708 | [['E02.319.267.050'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['C10.228.140.300.535.200', 'C14.907.253.573.200', 'C23.550.414.913.100'], ['E02.880.301', 'E04.292.451'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614.521'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Der(16)t(1;16)(q10;p10) in multiple myeloma: a new non-random abnormality that is frequently associated with Burkitt's-type translocations. | Aneuploidy is a frequent feature in multiple myeloma. Cytogenetic analyses have shown that a 14q+ chromosome resulting from either a t(8;14)(q24;q32) or a t(11;14)(q13;q32) was the most consistent abnormality but no specific chromosomal aberration has been identified in this disease. Bone marrow cells from 121 consecut... | ['Adult', 'Aged', 'Aneuploidy', 'Bone Marrow', 'Burkitt Lymphoma', 'Chromosomes, Human, Pair 1', 'Chromosomes, Human, Pair 16', 'Clone Cells', 'Female', 'Humans', 'In Situ Hybridization, Fluorescence', 'Karyotyping', 'Male', 'Middle Aged', 'Monosomy', 'Multiple Myeloma', 'Translocation, Genetic', 'Trisomy', 'Tumor Cell... | 7,869,764 | [['M01.060.116'], ['M01.060.116.100'], ['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['A15.382.216'], ['C01.925.256.466.313.165', 'C01.925.928.313.165', 'C04.557.386.480.150.165', 'C15.604.515.569.480.150.165', 'C20.683.515.761.480.150.165'], ['A11.284.187.520.300.235.240', 'G05.360.162.520.300.235.240'], ... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Statistical assessment of biosimilarity based on relative distance between follow-on biologics. | In this paper, we propose a new three-arm parallel design to investigate biosimilarity between a biosimilar product and an innovator biological product by using relative distance based on the absolute mean differences. In the proposed design, one arm is for the biosimilar product and the other two arms are for the inno... | ['Algorithms', 'Biosimilar Pharmaceuticals', 'Drug Evaluation'] | 22,941,672 | [['G17.035', 'L01.224.050'], ['D20.215.261'], ['E05.290.625', 'E05.337.425']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Milk Fistula: Diagnosis, Prevention, and Treatment. | Milk fistula is an uncommon condition which occurs when there is an abnormal connection that forms between the skin surface and the duct in the breast of a lactating woman, resulting in spontaneous and often constant drainage of milk from this path of least resistance. A milk fistula is usually a complication that resu... | ['Abscess', 'Breast Diseases', 'Breast Feeding', 'Female', 'Fistula', 'Humans', 'Wound Healing', 'Young Adult'] | 26,590,107 | [['C01.830.025', 'C23.550.470.756.100'], ['C17.800.090'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['C23.300.575'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G16.762.891'], ['M01.060.116.815']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ethanol extract of Lycopus lucidus elicits positive inotropic effect via activation of Ca2+ entry and Ca2+ release in beating rabbit atria. | Lycopus lucidus Turcz has been widely used as a traditional Oriental medicine (TOM) in Korea and China and prescribed for the enhancement of heart function. However, the precise effects have yet to be defined. The purpose of the present study was, therefore, to address whether the ethanol extract of Lycopus lucidus Tur... | ['Animals', 'Biological Transport', 'Calcium', 'Calcium Channels, L-Type', 'Cardiotonic Agents', 'Cyclic AMP', 'Drugs, Chinese Herbal', 'Heart Atria', 'In Vitro Techniques', 'Lycopus', 'Male', 'Rabbits', 'Stroke Volume'] | 23,875,903 | [['B01.050'], ['G03.143'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.530.400.150.400', 'D12.776.543.550.450.150.400', 'D12.776.543.585.400.150.400'], ['D27.505.954.411.222', 'D27.720.799.080'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], [... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Serotype profile and antibiotyping of Streptococcus pneumoniae strains isolated from nasal carriage in pediatric patients]. | The aim of this study was to determine the serotype profile and antibiotyping of Streptococcus pneumoniae from nasal isolates in children. Nasopharyngeal swab samples obtained from 125 children were cultivated and screened for the presence of S. pneumoniae. Strains were identified according to standard microbiological ... | ['Carrier State', 'Child, Preschool', 'Female', 'Humans', 'Infant', 'Male', 'Nose', 'Serotyping', 'Streptococcal Infections', 'Streptococcus pneumoniae'] | 16,562,641 | [['N06.850.520.169'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['A01.456.505.733', 'A04.531', 'A09.531'], ['E01.370.225.812.742', 'E01.370.225.875.150.125.890', 'E05.200.812.742', 'E05.200.875.150.125.890', 'E05.478.594.780'], ['C01.150.252.410.890'], ['B03.353.750.737.872.... | ['Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis, structural characterization and antimicrobial activities of 12 zinc(II) complexes with four thiosemicarbazone and two semicarbazone ligands. | Twelve zinc(II) complexes with thiosemicarbazone and semicarbazone ligands were prepared and characterized by elemental analysis, thermogravimetric and differential thermal analysis (TG/DTA), FT-IR and 1H and 13C NMR spectroscopy. Seven three-dimensional structures of zinc(II) complexes were determined by single-crysta... | ['Anti-Bacterial Agents', 'Anti-Infective Agents', 'Bacteria', 'Crystallography, X-Ray', 'Ligands', 'Microbial Sensitivity Tests', 'Mitosporic Fungi', 'Molecular Structure', 'Organometallic Compounds', 'Semicarbazones', 'Structure-Activity Relationship', 'Thiosemicarbazones', 'Yeasts', 'Zinc'] | 12,888,265 | [['D27.505.954.122.085'], ['D27.505.954.122'], ['B03'], ['E05.196.309.742.225'], ['D27.720.470.480'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.337.550.400'], ['B01.300.381'], ['G02.111.570', 'G02.466'], ['D02.691'], ['D02.845.746'], ['G02.111.830', 'G07.690.773.997'], ['D02.845.746.703', 'D02.886.803'], ['B01.30... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lifetime, 5-year and past-year prevalence of homelessness in Europe: a cross-national survey in eight European nations. | OBJECTIVES: To examine the lifetime, 5-year and past-year prevalence of homelessness among European citizens in eight European nations.DESIGN: A nationally representative telephone survey using trained bilingual interviewers and computer-assisted telephone interview software.SETTING: The study was conducted in France, ... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Europe', 'Female', 'Homeless Persons', 'Humans', 'Linear Models', 'Male', 'Middle Aged', 'Prevalence', 'Risk Factors', 'Socioeconomic Factors', 'Surveys and Questionnaires', 'Time Factors', 'Young Adult'] | 31,791,966 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.542'], ['M01.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[The CO2 laser treatment of benign laryngeal stenosis in patients undergoing horizontal supraglottic laryngectomy]. | One of the indications for CO2 laser surgery in benign laryngeal disease is the treatment of stenosis. Thirty-two patients with laryngeal stenosis after partial horizontal surgery of the larynx were treated with endoscopic CO2 laser surgery. The presence of laryngeal stenosis either impeded decannulation or produced dy... | ['Adult', 'Aged', 'Cicatrix', 'Glottis', 'Humans', 'Laryngectomy', 'Laryngostenosis', 'Laser Therapy', 'Male', 'Middle Aged', 'Postoperative Complications', 'Radiotherapy, Adjuvant', 'Time Factors'] | 10,502,699 | [['M01.060.116'], ['M01.060.116.100'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['A04.329.364'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.580.369'], ['C08.360.591', 'C09.400.591', 'C16.131.740.658'], ['E02.594', 'E04.014.520'], ['M01.060.116.630'], ['C23.550.767'], ['E02.186.775', 'E02.8... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Structure-activity relationship of Triterpenes and derived Glycosides against cancer cells and mechanism of apoptosis induction. | Triterpenoids possess a wide range of biological effects. Here, the cytotoxic activities of 55 triterpenes and derived glycosides against BEL-7404 and SGC-7901 cells were assessed, and structure-activity relationships were analysed accordingly. Nine of them effectively inhibited the two cell lines. In particular, compo... | ['Antineoplastic Agents, Phytogenic', 'Apoptosis', 'Cell Line, Tumor', 'DNA Fragmentation', 'Dose-Response Relationship, Drug', 'Gene Expression Regulation, Neoplastic', 'Glycosides', 'Humans', 'Inhibitory Concentration 50', 'Proto-Oncogene Proteins c-bcl-2', 'Structure-Activity Relationship', 'Triterpenes', 'bcl-2-Ass... | 28,662,592 | [['D27.505.954.248.179'], ['G04.146.954.035'], ['A11.251.210.190', 'A11.251.860.180'], ['G05.200.230'], ['G07.690.773.875', 'G07.690.936.500'], ['G05.308.370'], ['D09.408'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.940.350', 'G07.690.936.563'], ['D12.644.360.075.718', 'D12.776.476.075.718', 'D12.776.624.6... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence and predictors of anxiety and depression in women with invasive ovarian cancer and their caregivers. | OBJECTIVES: To assess the prevalence and predictors of depression and anxiety in women with ovarian cancer and their caregivers, to compare levels of depression and anxiety with community norms, and to explore the relationship between patients and their nominated caregivers.DESIGN, SETTING AND PARTICIPANTS: Prospective... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anxiety', 'Australia', 'Caregivers', 'Cohort Studies', 'Comorbidity', 'Depression', 'Female', 'Humans', 'Mental Health', 'Middle Aged', 'Ovarian Neoplasms', 'Prevalence', 'Prospective Studies', 'Psychiatric Status Rating Scales', 'Quality of Life', 'Regression Analysis', 'Severit... | 21,542,447 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['F01.470.132'], ['Z01.639.100', 'Z01.678.100.373'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N05.715.350.225', 'N06.850.490.687'], ['F01.145.126.350'], ['B01.050.150.90... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Conjunctival oculosporidiosis in east Africa caused by Rhinosporidium seeberi. | BACKGROUND AND OBJECTIVE: Conjunctival rhinosporidiosis is an infectious disease rarely recorded outside the Indian subcontinent. The disease is caused by Rhinosporidium seeberi, an endosporulating microorganism of uncertain taxonomic classification. We report a series of cases manifesting this infection.MATERIAL AND M... | ['Adolescent', 'Adult', 'Child', 'Conjunctival Diseases', 'Female', 'Humans', 'Kenya', 'Malawi', 'Male', 'Periodic Acid-Schiff Reaction', 'Rhinosporidiosis', 'Rhinosporidium', 'Silver Staining', 'Staining and Labeling'] | 9,140,291 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['C11.187'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.058.290.120.400'], ['Z01.058.290.175.500'], ['E01.370.225.500.607.790', 'E01.370.225.500.620.670.615', 'E01.370.225.750.551.790', 'E05.200.500.607.790', 'E05.200.500.620.670.620', 'E05.200.750.551.790... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Antibiotic prophylaxis in clean neck dissections. | This study was designed to evaluate the effects of a prophylactic antibiotic regimen on the incidence of wound infection after clean neck dissections. A prospective series of 57 patients undergoing clean neck dissections with the use of perioperative ampicillin-sulbactam for 24 hours was compared with an historical con... | ['Ampicillin', 'Anti-Bacterial Agents', 'Antibiotic Prophylaxis', 'Female', 'Head and Neck Neoplasms', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Neck Dissection', 'Prospective Studies', 'Sulbactam', 'Surgical Wound Infection'] | 15,068,519 | [['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['D27.505.954.122.085'], ['E02.319.162.150', 'E02.319.703.150'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['M01.060.116.630'], ['E04.446.318', 'E04.580.411'], ... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prevalence of comorbidities according to predominant phenotype and severity of chronic obstructive pulmonary disease. | BACKGROUND: In addition to lung involvement, several other diseases and syndromes coexist in patients with chronic obstructive pulmonary disease (COPD). Our purpose was to investigate the prevalence of idiopathic arterial hypertension (IAH), ischemic heart disease, heart failure, peripheral vascular disease (PVD), diab... | ['Aged', 'Comorbidity', 'Female', 'Humans', 'Italy', 'Lung', 'Male', 'Middle Aged', 'Phenotype', 'Prevalence', 'Pulmonary Disease, Chronic Obstructive', 'Pulmonary Emphysema', 'Retrospective Studies', 'Risk Factors', 'Severity of Illness Index'] | 27,695,310 | [['M01.060.116.100'], ['N05.715.350.225', 'N06.850.490.687'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['A04.411'], ['M01.060.116.630'], ['G05.695'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['C08.381.495.389'], ['C08.381.... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Phases of progressive burnout and their work site covariants: critical issues in OD research and praxis. | The term "burnout" represents a significant perspective on how people respond to their work, but the attention paid to this phenomenon has largely been clinical and often anecdotal. In this article, the authors seek to expand the analysis of burnout in ways that permit comparative analysis, especially in large populati... | ['Analysis of Variance', 'Burnout, Professional', 'Humans', 'Job Satisfaction', 'Models, Psychological', 'Stress, Psychological'] | 10,265,310 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['C24.580.500', 'F01.145.126.990.367.500', 'F02.830.900.333.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.784.692.425'], ['E05.599.695'], ['F01.145.126.990', 'F02.830.900']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Major Histocompatibility Complex, demographic, and environmental predictors of antibody presence in a free-ranging mammal. | Major Histocompatibility Complex (MHC) variability plays a key role in pathogen resistance, but its relative importance compared to environmental and demographic factors that also influence resistance is unknown. We analyzed the MHC II DRB exon 2 for 165 raccoons (Procyon lotor) in Missouri (USA). For each animal we al... | ['Animals', 'Antibodies, Viral', 'Distemper', 'Distemper Virus, Canine', 'Female', 'Immunoglobulin G', 'Immunoglobulin M', 'Major Histocompatibility Complex', 'Male', 'Models, Genetic', 'Parvoviridae Infections', 'Parvovirus', 'Raccoons'] | 25,446,941 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['C01.925.782.580.600.500.285', 'C22.268.265'], ['B04.820.480.937.600.650.500.280'], ['D12.776.124.486.485.114.619.393', 'D12.776.124.790.651.114.619.393', 'D12.776.377.715.548.114.619.393'], ['D12.776.124.486.4... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biological activity of 19-nor, 10-keto, 25-hydroxyvitamin D3. | 19 nor, 10 keto, 25-hydroxyvitamin D3 (19/10-25OHD3) is a metabolite of 25-OHD3 produced in vitro by various phagocytes including normal human blood monocytes and transformed cell lines, U937 and HL-60. We recently reported that 19/10-25OHD3, induced differentiation of U937 cells. In these studies, 19/10-25OHD3 alone p... | ['Calcifediol', 'Cell Adhesion', 'Cell Line', 'Cytochrome P-450 Enzyme System', 'Fibroblasts', 'Humans', 'Phagocytosis', 'Receptors, Calcitriol', 'Receptors, Steroid', 'Steroid Hydroxylases', 'Tumor Cells, Cultured', 'Vitamin D3 24-Hydroxylase'] | 3,455,623 | [['D04.210.500.247.222.159.478.250', 'D04.210.500.247.808.146.478.250', 'D04.210.500.812.768.196.478.250', 'D10.570.938.146.478.250'], ['G04.022'], ['A11.251.210'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G04.417.350', 'G09.1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Proteomic DIGE analysis of the mitochondria-enriched fraction from aged rat skeletal muscle. | Skeletal muscle aging is associated with a loss in tissue mass and contractile strength, as well as fiber type shifting and bioenergetic adaptation processes. Since mitochondria represent the primary site for energy generation via oxidative phosphorylation, we investigated potential changes in the expression pattern of... | ['Aging', 'Animals', 'Electrophoresis, Gel, Two-Dimensional', 'Mitochondria, Muscle', 'Mitochondrial Proteins', 'Muscle Fibers, Skeletal', 'Muscle, Skeletal', 'Proteome', 'Proteomics', 'Rats', 'Rats, Wistar'] | 19,834,913 | [['G07.345.124'], ['B01.050'], ['E05.196.401.250', 'E05.301.300.230'], ['A11.284.430.214.190.875.564.627', 'A11.284.835.626.627'], ['D12.776.575'], ['A10.690.552.500.500', 'A11.620.249'], ['A02.633.567', 'A10.690.552.500'], ['D12.776.817'], ['H01.158.201.843', 'H01.158.273.180.350.700', 'H01.158.273.343.350.700', 'H01.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Screening for Cellulase Encoding Clones in Metagenomic Libraries. | For modern biotechnology there is a steady need to identify novel enzymes. In biotechnological applications, however, enzymes often must function under extreme and nonnatural conditions (i.e., in the presence of solvents, high temperature and/or at extreme pH values). Cellulases have many industrial applications from t... | ['Biotechnology', 'Cellulase', 'Cellulose', 'Chromatography, High Pressure Liquid', 'Chromatography, Thin Layer', 'Enzyme Activation', 'Gene Library', 'Hydrolysis', 'Metagenome', 'Metagenomics'] | 27,900,691 | [['H01.158.550', 'J01.897.120'], ['D08.811.277.450.420.200.200'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['E05.196.181.400.300'], ['E05.196.181.400.537'], ['G02.111.263', 'G03.328'], ['G05.360.325'], ['G02.380'], ['G05.360.340.550'], ['H01.158.273.343.350.261']] | ['Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Gastric mucosal function following withdrawal of omeprazole in rats. | In the following study the function of gastric mucosa after withdrawal of 4-week suppression of acid secretion was examined. Rats were treated orally for 4 weeks with omeprazole (CAS 73590-58-6, 150 mg/kg/day). While elevated plasma gastrin levels during the treatment returned to normal 4 days after the last dosing, ex... | ['Analgesics, Non-Narcotic', 'Animals', 'Anti-Ulcer Agents', 'Aspirin', 'Gastric Acid', 'Gastric Mucosa', 'Gastrins', 'Histamine', 'Male', 'Omeprazole', 'Rats', 'Rats, Sprague-Dawley', 'Substance Withdrawal Syndrome'] | 9,522,036 | [['D27.505.696.663.850.014.040', 'D27.505.954.427.040.100'], ['B01.050'], ['D27.505.954.483.203'], ['D02.455.426.559.389.657.410.595.176'], ['A12.200.307.603'], ['A03.556.875.875.440', 'A10.615.550.291'], ['D06.472.317.413', 'D06.472.699.280', 'D12.644.400.320', 'D12.644.548.280', 'D12.776.631.650.320'], ['D02.092.211.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Demonstration of a S-methyl metabolite of captopril in patients undergoing chronic captopril therapy. | 1. The formation of the S-methyl metabolite of captopril has been demonstrated for the first time in the urine of five patients receiving chronic captopril therapy. 2. Patients were studied following a 100 mg oral dose of captopril. 3. Excretion values for S-methylcaptopril were 0.66 mg and 0.31 mg at 0-3 h and 3-6 h p... | ['Captopril', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Hypertension', 'Methylation', 'Middle Aged', 'Proline'] | 6,754,187 | [['D12.125.072.401.623.270'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['M01.060.116.630'], ['D12.125.072.401.623']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Identification of novel sulfur-containing derivatives of chlorophyll a in a Recent sediment. | Novel transformation products of chlorophyll a incorporating a methyl sulfide group in the substituent at the C-3 position have been identified in Recent sediments from an Antarctic lake. | ['Chlorophyll', 'Chlorophyll A', 'Chromatography, High Pressure Liquid', 'Geologic Sediments', 'Magnetic Resonance Spectroscopy', 'Sulfur Compounds'] | 12,669,856 | [['D03.383.129.578.840.374', 'D03.633.400.909.374', 'D04.345.783.374'], ['D03.383.129.578.840.374.140', 'D03.633.400.909.374.140', 'D04.345.783.374.140'], ['E05.196.181.400.300'], ['G01.311.330', 'G16.500.320'], ['E05.196.867.519'], ['D01.875', 'D02.886']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of the mdr3 gene in prolymphocytic leukemia: association with cyclosporin-A-induced increase in drug accumulation. | Typical multidrug resistance in human and animal cell lines is caused by overactivity of an unidirectional transmembrane drug efflux pump, encoded by the MDR genes, called mdr genes in mice and humans and pgp genes in hamsters. In humans, two mdr genes, mdr1 and mdr3, with approximately 80% nucleotide homology, have be... | ['Adult', 'Aged', 'B-Lymphocytes', 'Cyclosporins', 'Daunorubicin', 'Drug Resistance', 'Female', 'Gene Expression Regulation, Leukemic', 'Genes', 'Humans', 'Leukemia, Prolymphocytic', 'Male', 'Middle Aged', 'RNA, Messenger', 'RNA, Neoplasm'] | 2,323,839 | [['M01.060.116'], ['M01.060.116.100'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D04.345.566.235', 'D12.644.641.235'], ['D02.455.426.559.847.562.050.200', 'D04.615.562.050.200', 'D09.408.051.059.200'], ['G07.690.773.984'], ['G05.308.370.50... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Traumatic carpal instability. | In general, two patterns of traumatic carpal instability can be discerned: palmar flexion intercalated segmental instability (PISI deformity) and dorsiflexion intercalated segmental instability (DISI deformity). Two case reports are described, demonstrating both types and their treatment. PISI deformity, seen less freq... | ['Adult', 'Bone Wires', 'Carpal Bones', 'Female', 'Humans', 'Joint Instability', 'Male', 'Radiography', 'Wrist Joint'] | 3,773,008 | [['M01.060.116'], ['E07.695.370.468', 'E07.858.442.660.460.468', 'E07.858.690.725.460.468'], ['A02.835.232.087.319.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['E01.370.350.700'], ['A02.835.583.405.930']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Anthocyanin-rich extracts from blackberry, wild blueberry, strawberry, and chokeberry: antioxidant activity and inhibitory effect on oleic acid-induced hepatic steatosis in vitro. | BACKGROUND: Limited information is available regarding the relationship between the chemical structures and inhibitory effects of anthocyanin (ACN) on triglyceride (TG) overaccumulation. Thus this study investigated the antioxidant activity and inhibitory effect of blackberry, wild blueberry, strawberry, and chokeberry... | ['Animals', 'Anthocyanins', 'Antioxidants', 'Blueberry Plants', 'Fatty Liver', 'Fragaria', 'Fruit', 'Hep G2 Cells', 'Humans', 'Lipid Metabolism', 'Oleic Acid', 'Plant Extracts', 'Prunus', 'Rubus'] | 26,250,597 | [['B01.050'], ['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['B01.650.940.800.575.912.250.341.937.774.249'], ['C06.552.241'], ['B01.650.940.800.575.912.250.859.937.500.266'], ['A18.024.500', 'G07.203.300.562',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Human cytomegalovirus DNA in cerebrospinal fluid. | To determine the involvement of human cytomegalovirus (CMV) in conditions of neurological impairment, detection of CMV DNA was attempted in cerebrospinal fluid obtained from 45 neurologically affected children aged from 1 month to 17 years by means of the polymerase chain reaction. Four patients (congenital CMV encepha... | ['Adolescent', 'Brain Diseases', 'Cerebral Cortex', 'Child', 'Child, Preschool', 'Cytomegalovirus', 'Cytomegalovirus Infections', 'DNA, Viral', 'Encephalitis, Viral', 'Epilepsy', 'Female', 'Humans', 'Infant', 'Male', 'Polymerase Chain Reaction'] | 7,826,111 | [['M01.060.057'], ['C10.228.140'], ['A08.186.211.200.885.287.500'], ['M01.060.406'], ['M01.060.406.448'], ['B04.280.382.150.150'], ['C01.925.256.466.245'], ['D13.444.308.568'], ['C01.207.245.340', 'C01.207.399.750', 'C01.925.182.525', 'C10.228.140.430.520.750', 'C10.228.228.245.340', 'C10.228.228.399.750'], ['C10.228.1... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Acceptability of multiple micronutrient supplements by pregnant and lactating women in Mali. | BACKGROUND: In Mali, an estimated 73% of pregnant women are anaemic largely due to iron deficiency. National policy recommends women to take iron and folic acid supplements daily from first prenatal contact until 3 months postpartum. However, many pregnant women in Mali could benefit from multiple micronutrient supplem... | ['Adolescent', 'Adult', 'Anemia, Iron-Deficiency', 'Dietary Supplements', 'Female', 'Folic Acid', 'Folic Acid Deficiency', 'Humans', 'Iron', 'Lactation', 'Mali', 'Micronutrients', 'Patient Acceptance of Health Care', 'Patient Compliance', 'Postpartum Period', 'Pregnancy', 'Pregnancy Outcome', 'Prenatal Care'] | 15,705,243 | [['M01.060.057'], ['M01.060.116'], ['C15.378.071.196.300', 'C18.452.565.100'], ['G07.203.300.456', 'J02.500.456'], ['D03.633.100.733.631.400'], ['C18.654.521.500.133.699.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['G08.686.523', 'G08.686.702.500'],... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
[Recurrent acoustic neurinoma after complete surgical resection]. | BACKGROUND: Mortality of acoustic neurinoma surgery is currently very low, well below the figures reported by the first surgeons. Morbidity has also declined with attempts at preserving the facial function and more recently hearing function. Long-term follow-up has demonstrated the well-known risk of recurrence after p... | ['Adolescent', 'Adult', 'Aged', 'Female', 'Follow-Up Studies', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neuroma, Acoustic'] | 11,240,431 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['C04.557.465.625.650.595.610', 'C04.557.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
ERâ expression in the endothelium ameliorates ischemia/reperfusion-mediated oxidative burst and vascular injury. | Estrogen and estrogen receptors (ERs) have been reported to play protective roles in ischemia/reperfusion (I/R)-mediated injury, but the detailed mechanism remains to be fully understood. Nitric oxide (NO) and reactive oxygen species (ROS) also play important roles in the I/R process; however, due to the lack of sensit... | ['Animals', 'DNA Damage', 'Endothelial Cells', 'Endothelium, Vascular', 'Estrogen Receptor beta', 'Mitochondria', 'Myocardial Infarction', 'Myocytes, Cardiac', 'Nitric Oxide', 'Nitric Oxide Synthase Type III', 'Rats', 'Reactive Oxygen Species', 'Receptors, Estrogen', 'Reperfusion Injury', 'Respiratory Burst', 'Superoxi... | 27,130,032 | [['B01.050'], ['G05.200'], ['A11.436.275'], ['A07.015.700.500', 'A10.272.491.355'], ['D12.776.826.750.350.262'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750'], ['A07.541.704.570', 'A10.690.552.750.570', 'A11.620.500'], ['D01.339.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The effect of cocaine on rotarod performance in male C57BL/6J mice. | There is surprisingly little research examining the effect of cocaine on motor learning. Given that changes in motor activity can confound behavioral assays of learning and memory a direct assessment of cocaine on motor learning seems warranted. The present study was conducted to examine the effect of cocaine on motor ... | ['Analysis of Variance', 'Animals', 'Central Nervous System Stimulants', 'Cocaine', 'Dose-Response Relationship, Drug', 'Learning', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Motor Activity', 'Postural Balance', 'Psychomotor Performance', 'Rotarod Performance Test'] | 23,688,950 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['D27.505.696.282', 'D27.505.954.427.220'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['G07.690.773.875', 'G07.690.936.500'], ['F02.463.425', 'F02.784.629.529'], ['B01.050.150.900.649.313.992... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of DX-8951f and topotecan effects on tumor colony formation from freshly explanted adult and pediatric human tumor cells. | DX-8951f, which shows great therapeutic potential, was tested in the human tumor cloning system in adult and pediatric tumor types against which topotecan has been active. In 47 tumors from adults, DX-8951f had definite cytotoxic activity in a concentration-dependent manner with both 1 h and continuous exposures. Topot... | ['Adult', 'Antineoplastic Agents, Phytogenic', 'Camptothecin', 'Child', 'Dose-Response Relationship, Drug', 'Humans', 'Irinotecan', 'Neoplastic Stem Cells', 'Topotecan', 'Tumor Cells, Cultured'] | 10,507,315 | [['M01.060.116'], ['D27.505.954.248.179'], ['D03.132.151'], ['M01.060.406'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.132.151.425'], ['A11.872.650'], ['D03.132.151.850'], ['A11.251.860']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The mouse Necdin gene is expressed from the paternal allele only and lies in the 7C region of the mouse chromosome 7, a region of conserved synteny to the human Prader-Willi syndrome region. | Prader-Willi syndrome (PWS) is a neurogenetic disorder resulting from the loss of paternal expression of gene(s) localized in the 15q11-q12 region. A new human gene encoding a putative protein with high homology to the mouse NECDIN protein has recently been characterized and mapped to chromosome 15q11-q12. It is expres... | ['Alleles', 'Animals', 'Base Sequence', 'Brain', 'Brain Chemistry', 'Chromosome Mapping', 'Conserved Sequence', 'Crosses, Genetic', 'DNA Methylation', 'DNA Replication', 'Female', 'Fetus', 'Gene Expression Regulation, Developmental', 'Genomic Imprinting', 'Humans', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Molecular Seque... | 9,412,790 | [['G05.360.340.024.340.030'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A08.186.211'], ['G02.111.150', 'G03.185'], ['E05.393.183'], ['G02.111.570.580'], ['E05.393.281'], ['G02.111.035.538.161', 'G02.111.218', 'G03.059.538.161', 'G05.206'], ['G02.111.225', 'G05.226'], ['A16.378'], ['G05.3... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Proposal of a new prognostic model for hepatocellular carcinoma: an analysis of 403 patients. | BACKGROUND: The prognosis of hepatocellular carcinoma (HCC) is highly dependent on tumour extension and liver function. Recently, two new prognostic scoring systems-the CLIP score, developed by Italian investigators and the BCLC score, developed in Barcelona-have been widely used to assess prognosis in patients present... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bilirubin', 'Biomarkers', 'Carcinoma, Hepatocellular', 'Female', 'Humans', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Prognosis', 'Reproducibility of Results', 'Serum Albumin', 'Severity of Illness Index', 'Survival Analysis', 'Treatment Outcome'... | 15,710,994 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D03.383.129.578.840.249.184', 'D03.633.400.909.249.184', 'D04.345.783.249.184', 'D23.767.193.184'], ['D23.101'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['B01.050.150.900.649.313.988.400.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The sudden removal of user fees: the perspective of a frontline manager in Burundi. | In May 2006, the President of Burundi announced the removal of user fees in all health centres and hospitals for children under 5 and women giving birth. As other studies also point out, the policy was adopted extremely suddenly, without much reflection on its ultimate aims and on the operational dimension of its imple... | ['Burundi', 'Fees and Charges', 'Health Services Accessibility', 'Humans', 'Organizational Case Studies', 'Public Policy'] | 22,027,921 | [['Z01.058.290.120.180'], ['N03.219.442'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.349.380.710', 'N05.715.360.455'], ['I01.655.500.608', 'I01.880.604.825.608', 'N03.623.500.608']] | ['Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Paclitaxel activation of the GADD153 promoter through a cellular injury response element containing an essential Sp1 binding site. | The GADD153 promoter is transcriptionally activated by paclitaxel-induced injury. Promoter deletion from -786 to -85 base pairs relative to the start of transcription had no significant effect on activation, but deletion to the TATA box abolished it. Placement of the 39 bases from -74 to the TATA box (cellular injury r... | ['Base Sequence', 'Binding Sites', 'CCAAT-Enhancer-Binding Proteins', 'DNA Damage', 'DNA Footprinting', 'DNA Mutational Analysis', 'DNA-Binding Proteins', 'Gene Expression', 'Humans', 'Molecular Sequence Data', 'Paclitaxel', 'Promoter Regions, Genetic', 'RNA, Messenger', 'Sp1 Transcription Factor', 'Transcription Facto... | 8,702,804 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D12.776.260.108.124', 'D12.776.660.167', 'D12.776.930.127.124'], ['G05.200'], ['E05.393.300'], ['E05.393.760.700.300'], ['D12.776.260'], ['G05.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['D02.455.426.392... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Diagnosing the pathophysiologic mechanisms of nocturnal polyuria. | BACKGROUND: Diagnosis of nocturnal polyuria (NP) is based on a bladder diary. Addition of a renal function profile (RFP) for analysis of concentrating and solute-conserving capacity allows differentiation of NP pathophysiology and could facilitate individualized treatment.OBJECTIVE: To map circadian rhythms of water an... | ['Adult', 'Aged', 'Belgium', 'Biomarkers', 'Case-Control Studies', 'Circadian Rhythm', 'Creatinine', 'Diuresis', 'Female', 'Humans', 'Male', 'Middle Aged', 'Natriuresis', 'Osmolar Concentration', 'Polyuria', 'Predictive Value of Tests', 'Prospective Studies', 'Sodium', 'Time Factors', 'Urinalysis', 'Urinary Bladder', '... | 25,240,972 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.542.115'], ['D23.101'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['G07.180.562.190'], ['D03.383.129.308.207'], ['G08.852.179'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G08.852.179.557'], ['G02.640'], ['C12... | ['Named Groups [M]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
CT and MRI findings of calcified spinal meningiomas: correlation with pathological findings. | OBJECTIVE: This study was designed to present characteristic CT and MR findings of calcified spinal meningiomas that correlate with pathological findings and to assess the efficacy of CT for the detection of calcifications within a mass in comparison to MRI.MATERIALS AND METHODS: Between 1998 and 2009, 10 out of 11 pat... | ['Adult', 'Aged', 'Calcinosis', 'Female', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Meningeal Neoplasms', 'Meningioma', 'Middle Aged', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Spinal Neoplasms', 'Statistics as Topic', 'Tomography, X-Ray Computed'] | 19,685,049 | [['M01.060.116'], ['M01.060.116.100'], ['C18.452.174.130'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C04.588.614.250.580', 'C10.551.240.500'], ['C04.557.580.520', 'C04.557.645.520', 'C04.588.614.250.580.500', 'C10.551.240.500.500'], ['M01.060.116.630'], ['E05.318.370.725', 'E05.337.85... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[The reaction of firing motor units to afferent pulses]. | Afferent stimulation of the human motor units was unstable in its effect during the first 250 msec. Peristimulus time histograms were specifically individual for a single motor unit. The motor units altered their firing rate in response to afferent volleys depending on the background firing rate of the motoneurons. | ['Afferent Pathways', 'Animals', 'Electric Stimulation', 'Electrodes', 'Hand', 'Humans', 'Median Nerve', 'Motor Neurons', 'Rats', 'Restraint, Physical', 'Sciatic Nerve', 'Time Factors'] | 8,829,674 | [['A08.612.220'], ['B01.050'], ['E05.723.402'], ['E07.305.250'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800.720.050.500'], ['A08.675.655.500', 'A11.671.655.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['E02.085.700', 'E05.472.760'], ['A08.800.800.720.450.760'], ['G01.910.... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Creating a free muscle flap by neovascularization: an experimental investigation. | Experimental free muscle flaps were created by inducing transmural neovascularization. Free muscle flaps were developed in Sprague-Dawley rats through a three-stage microsurgical procedure. In the first stage, a muscle strip from the external oblique abdominus muscle was elevated and folded around the superficial epiga... | ['Animals', 'Arteries', 'Graft Survival', 'Male', 'Microsurgery', 'Muscles', 'Neovascularization, Pathologic', 'Rats', 'Rats, Inbred Strains', 'Surgical Flaps', 'Veins'] | 2,445,988 | [['B01.050'], ['A07.015.114'], ['G12.875.545.340'], ['E04.494', 'E05.591.580'], ['A02.633', 'A10.690'], ['C23.550.589.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['A10.850.710', 'E07.862.710'], ['A07.015.908']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Time of fixation and the localization of Gomori-positive and neurophysin-containing structures in the rat hypothalamus. | Rats were decapitated and the complete head stored at 4 degrees C. At various time intervals, up to a maximum of 14 days, the brains and pituitary glands were removed and fixed in formalin-picric acid. Neurosecretory material (NSM), as revealed with crotonaldehyde fuchsin, and neurophysin as demonstrated by means of im... | ['Animals', 'Cold Temperature', 'Histological Techniques', 'Hypothalamo-Hypophyseal System', 'Male', 'Median Eminence', 'Neurophysins', 'Paraventricular Hypothalamic Nucleus', 'Pituitary Gland, Posterior', 'Rats', 'Supraoptic Nucleus', 'Time Factors', 'Tissue Preservation'] | 1,102,105 | [['B01.050'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['E01.370.225.750', 'E05.200.750'], ['A06.688.357', 'A08.186.211.180.497.352.435', 'A08.186.211.200.317.357.352.435', 'A08.713.357'], ['A06.688.178.750', 'A06.688.357.50... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Molecular characteristics and prognostic features of breast cancer in Nigerian compared with UK women. | Although breast cancer (BC) incidence is lower in African-American women compared with White-American, in African countries such as Nigeria, BC is a common disease. Nigerian women have a higher risk for early-onset, with a high mortality rate from BC, prompting speculation that risk factors could be genetic and the mol... | ['African Continental Ancestry Group', 'Biomarkers, Tumor', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Disease-Free Survival', 'European Continental Ancestry Group', 'Female', 'Humans', 'Kaplan-Meier Estimate', 'Lymphatic Metastasis', 'Middle Aged', 'Multivariate Analysis', 'Neoplasm Invasiveness', 'Nigeria', 'P... | 22,842,985 | [['M01.686.508.100'], ['D23.101.140'], ['C04.588.180', 'C17.800.090.500'], ['C04.557.470.200.025.232.500', 'C04.557.470.615.132.500', 'C04.588.180.390', 'C17.800.090.500.390'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.83... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Upper extremity amputations after motor vehicle rollovers. | BACKGROUND: The upper extremity is vulnerable to injury during a rollover motor vehicle crash (MVC). There is some concern that positioning one's arm on a vehicle door/window eliminates the benefit of maintaining containment within a protective structure. Mangled extremities with associated vascular injuries have an am... | ['Accidents, Traffic', 'Adult', 'Amputation', 'Cohort Studies', 'Extremities', 'Female', 'Humans', 'Male', 'Retrospective Studies', 'Wounds, Nonpenetrating'] | 19,667,899 | [['N06.850.135.392'], ['M01.060.116'], ['E04.555.080'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['A01.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.8... | ['Health Care [N]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Low-dose radiation-induced enhancement of thymic lymphomagenesis in Lck-Bax mice is dependent on LET and gender. | The hypothesis that mitochondrial dysfunction and increased superoxide levels in thymocytes over expressing Bax (Lck-Bax1 and Lck-Bax38&1) contributes to lymphomagenesis after low-dose radiation was tested. Lck-Bax1 single-transgenic and Lck-Bax38&1 double-transgenic mice were exposed to single whole-body doses of 10 o... | ['Animals', 'Cesium Radioisotopes', 'Dose-Response Relationship, Radiation', 'Female', 'Gene Dosage', 'Heavy Ions', 'Iron', 'Linear Energy Transfer', 'Lymphocyte Specific Protein Tyrosine Kinase p56(lck)', 'Lymphoma', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Mutant Strains', 'Mitochondria', 'Neoplasms, Radiation-In... | 23,819,597 | [['B01.050'], ['D01.268.549.125.500.300', 'D01.268.556.165.500.300', 'D01.496.180.300', 'D01.496.749.190', 'D01.552.528.160.500.300', 'D01.552.544.165.500.300'], ['E05.799.513.500', 'G01.750.740.500', 'G04.712.500', 'G07.225', 'G07.738.500', 'N06.850.810.250.180'], ['G05.380.350'], ['G01.249.467'], ['D01.268.556.412', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effects of S-allyl cysteine on lung and liver tissue in a rat model of lipopolysaccharide-induced sepsis. | Sepsis is characterized by a severe production of reactive oxygen species (ROS) and other radical species with consequent oxidative stress. S-allyl cysteine (SAC) is a water-soluble organosulfur component present in garlic which is a potent antioxidant and free radical scavenger. In the present study, the purpose was t... | ['Alanine Transaminase', 'Alkaline Phosphatase', 'Animals', 'Antioxidants', 'Aspartate Aminotransferases', 'C-Reactive Protein', 'Cysteine', 'DNA Fragmentation', 'Disease Models, Animal', 'Lipopolysaccharides', 'Liver', 'Lung', 'Male', 'Nitric Oxide', 'Peroxidase', 'Rats, Wistar', 'Sepsis'] | 25,480,742 | [['D08.811.913.477.700.100'], ['D08.811.277.352.650.035'], ['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D08.811.913.477.700.225'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['G05.200.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Analysis of possibility of genotypic correlation between fear and anxiety]. | Special features of anxious behavior in the elevated plus maze test and acoustic startle response were analyzed in 11 inbred mouse strains. A significant influence of the genotype both on the startle amplitude and behavior in the elevated plus maze was found. However, analysis of covariance did not reveal a genotype-re... | ['Animals', 'Anxiety', 'Fear', 'Genotype', 'Male', 'Mice', 'Mice, Inbred Strains', 'Reflex, Startle', 'Species Specificity'] | 11,550,640 | [['B01.050'], ['F01.470.132'], ['F01.470.361'], ['G05.380'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520', 'B01.050.150.900.649.313.992.635.505.500.400'], ['E01.370.376.550.650.800', 'E01.370.600.550.650.800', 'F02.830.702.807', 'G11.561.731.869'], ['G16.824']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Time interval for preterm infant weight gain velocity calculation precision. | Calculation of weight gain velocity is used to guide nutrition and fluid management practices in neonatal intensive care units. Calculations over short time periods may be more responsive to management changes, but less precise. Weight gain velocity calculated over 5 to 7+ days have lower variability and less noise tha... | ['Humans', 'Infant, Newborn', 'Infant, Premature', 'Intensive Care Units, Neonatal', 'Monitoring, Physiologic', 'Time Factors', 'Weight Gain'] | 29,997,166 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['N02.278.388.493.390.380'], ['E01.370.520'], ['G01.910.857'], ['C23.888.144.243.926', 'G07.345.249.314.120.200.926']] | ['Organisms [B]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Passive air monitoring of PCBs and PCNs across East Asia: a comprehensive congener evaluation for source characterization. | A comprehensive congener specific evaluation of polychlorinated biphenyls (PCBs) and polychlorinated naphthalenes (PCNs) in the atmosphere was conducted across East Asia in spring 2008, applying polyurethane foam (PUF) disk passive air sampler (PAS) as monitoring device. Mean concentrations derived for Japan, China and... | ['Air Pollutants', 'Asia', 'Atmosphere', 'Naphthalenes', 'Polychlorinated Biphenyls', 'Population Density', 'Principal Component Analysis'] | 22,113,058 | [['D27.888.284.101'], ['Z01.252'], ['G16.500.275.063', 'N06.230.300.100'], ['D02.455.426.559.847.638', 'D04.615.638'], ['D02.309.750', 'D02.455.426.559.389.185.698', 'D02.455.526.439.773'], ['N01.224.600', 'N06.850.505.400.600'], ['E05.318.740.562']] | ['Chemicals and Drugs [D]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Head and Neck Round Cell Sarcomas: A Comparative Clinicopathologic Analysis of 2 Molecular Subsets: Ewing and CIC-Rearranged Sarcomas. | CIC-rearranged sarcoma (CRS) is a relatively new entity defined by its pathognomonic genetic signature and undifferentiated round cell phenotype, initially grouped together with the 'Ewing sarcoma-like tumors'. However, increasing data suggest that these tumors should be regarded as a stand-alone pathologic entity. We ... | ['Adolescent', 'Adult', 'Aged', 'Bone Neoplasms', 'Child', 'Child, Preschool', 'Female', 'Gene Rearrangement', 'Head and Neck Neoplasms', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Repressor Proteins', 'Sarcoma, Ewing', 'Sarcoma, Small Cell', 'Soft Tissue Neoplasms', 'Young Adult'] | 28,337,592 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C04.588.149', 'C05.116.231'], ['M01.060.406'], ['M01.060.406.448'], ['G05.344'], ['C04.588.443'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.116.630'], ['D12.776.260.703', 'D12.776.930.780'], ['C04.557.450.565.575.650.800', 'C04.... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cost-effectiveness of canine vaccination to prevent human rabies in rural Tanzania. | BACKGROUND: The annual mortality rate of human rabies in rural Africa is 3.6 deaths per 100 000 persons. Rabies can be prevented with prompt postexposure prophylaxis, but this is costly and often inaccessible in rural Africa. Because 99% of human exposures occur through rabid dogs, canine vaccination also prevents tran... | ['Animals', 'Bites and Stings', 'Cost-Benefit Analysis', 'Dog Diseases', 'Dogs', 'Humans', 'Models, Statistical', 'Rabies', 'Rabies Vaccines', 'Rural Population', 'Tanzania', 'Vaccination'] | 24,592,494 | [['B01.050'], ['C25.723.127', 'C26.176'], ['N03.219.151.125'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['C01.925.782.580.830.750'], ['D20.215.894.899.700'], ['N01.600.725'... | ['Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[Early diagnosis of myocardial infarct: value of the combined use of creatine kinase and MB isoenzyme determinations]. | To define the optimal diagnostic strategy for acute myocardial infarction, 225 patients with suspected myocardial infarction were studied by serial (3 hour intervals) sampling for CK and CK-MB enzyme activity. In 12 patients the diagnosis of myocardial infarction was rejected. In the remaining 213 the myocardial infarc... | ['Clinical Enzyme Tests', 'Creatine Kinase', 'Humans', 'Isoenzymes', 'Myocardial Infarction'] | 4,007,360 | [['E01.370.225.124.200', 'E05.196.427.200', 'E05.200.124.200'], ['D08.811.913.696.640.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.348', 'D12.776.800.300'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.717.489.750']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Regulation of 2-methoxyestradiol-induced cell apoptosis by mcl-1 and bax genes in myelodysplastic syndrome]. | The purpose of this study was to explore the mechanism underlying the regulation of 2-methoxyestradiol (2-ME)-induced cell apoptosis by mcl-1 and bax gene in myelodysplastic syndrome (MDS). The MUTZ-1 cells were pretreated with 2-ME; then the activity of caspases-3 was determined by fluorescent colorimetry; the mRNA ex... | ['2-Methoxyestradiol', 'Apoptosis', 'Caspase 3', 'Cell Line, Tumor', 'Estradiol', 'Humans', 'Myelodysplastic Syndromes', 'Myeloid Cell Leukemia Sequence 1 Protein', 'Proto-Oncogene Proteins c-bcl-2', 'bcl-2-Associated X Protein'] | 19,840,460 | [['D04.210.500.365.415.248.830', 'D06.472.334.851.437.500.750'], ['G04.146.954.035'], ['D08.811.277.656.262.500.126.350.300', 'D08.811.277.656.300.200.126.350.300', 'D12.644.360.075.405.350.300', 'D12.776.476.075.405.350.300'], ['A11.251.210.190', 'A11.251.860.180'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ficolin-3 activity towards the opportunistic pathogen, Hafnia alvei. | Ficolin-3 (also called H-ficolin or Hakata antigen) is a complement-activating pattern recognition molecule, possessing a fibrinogen-like domain involved in carbohydrate binding. Amongst human ficolins, Ficolin-3 has the highest concentration in serum and is the most potent lectin pathway activator in vitro. Evidence f... | ['Agglutination', 'Cell Line', 'Enterobacteriaceae Infections', 'Glycoproteins', 'Hafnia alvei', 'Humans', 'Lectins', 'Lipopolysaccharides', 'Opportunistic Infections', 'Phagocytosis'] | 25,178,935 | [['G02.111.026', 'G12.122.100'], ['A11.251.210'], ['C01.150.252.400.310'], ['D09.400.430', 'D12.776.395'], ['B03.440.450.425.375.050', 'B03.660.250.150.280.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.503'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', 'D23.946.123.329.500']... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Bound to supine sleep: Parkinson's disease and the impact of nocturnal immobility. | BACKGROUND: Impaired nocturnal mobility is a well-known problem in Parkinson's disease (PD), and clinical experience suggests a predominance of supine body position during sleep. However, this assumption - and potential consequences - still awaits objective validation by a polysomnography-based and adequately controlle... | ['Aged', 'Female', 'Humans', 'Male', 'Middle Aged', 'Movement', 'Parkinson Disease', 'Polysomnography', 'Retrospective Studies', 'Sleep', 'Supine Position'] | 26,299,159 | [['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G07.568', 'G11.427.410'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750'], ['E01.370.520.625'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.7... | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Enzymatic synthesis of UDP-(3-deoxy-3-fluoro)-D-galactose and UDP-(2-deoxy-2-fluoro)-D-galactose and substrate activity with UDP-galactopyranose mutase. | The novel UDP-sugar uridine 5'-(3-deoxy-3-fluoro-D-galactopyranosyl diphosphate) (1) and UDP-(2-deoxy-2-fluoro)-D-galactose (2) have been prepared enzymatically and tested as substrate analogues for the enzyme UDP-galactopyranose mutase (UDP-Galp mutase EC 5.4.99.9). Turnover of both 1 and 2 by UDP-Galp mutase was obse... | ['Bacterial Proteins', 'Chromatography, High Pressure Liquid', 'Fluorine', 'Intramolecular Transferases', 'Kinetics', 'Nuclear Magnetic Resonance, Biomolecular', 'Substrate Specificity', 'Uridine Diphosphate Galactose'] | 11,093,703 | [['D12.776.097'], ['E05.196.181.400.300'], ['D01.268.380.300'], ['D08.811.399.520'], ['G01.374.661', 'G02.111.490'], ['E05.196.867.519.550'], ['G02.111.835'], ['D03.383.742.686.850.600.677.300', 'D09.408.620.569.727.300', 'D13.695.740.850.600.677.300', 'D13.695.827.708.727.300', 'D13.695.827.919.600.677.300']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Increased leukocyte aggregates are associated with atherosclerosis in patients with hemodialysis. | Little data are available on the role of blood rheology in atherosclerosis in hemodialysis (HD) patients. This study sought to assess the relationship between leukocytes conjugated with platelets (leukocyte aggregates [LA]) and atherosclerosis in patients with HD. The present study included 118 patients on HD. As surro... | ['Adult', 'Aged', 'Aged, 80 and over', 'Atherosclerosis', 'Blood Platelets', 'Blood Viscosity', 'Cell Aggregation', 'Female', 'Flow Cytometry', 'Humans', 'Leukocytes', 'Male', 'Middle Aged', 'Platelet Aggregation', 'Renal Dialysis', 'Rheology'] | 19,583,603 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.907.137.126.307'], ['A11.118.188', 'A15.145.229.188'], ['G09.188.370.124', 'G09.330.380.630.110'], ['G04.198.251'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Pattern of recurrence of trachomatous trichiasis after surgery surgical technique as an explanation. | OBJECTIVE: To evaluate the pattern of recurrence of trachomatous trichiasis (TT) after bilamellar tarsal rotation surgery for trachoma.DESIGN: Observational cohort.PARTICIPANTS: Three hundred eighty-four participants having at least 1 eye that had undergone a single TT surgery a minimum of 18 months before June 2001. T... | ['Aged', 'Chlamydia trachomatis', 'Eyelashes', 'Eyelid Diseases', 'Female', 'Functional Laterality', 'Hair Diseases', 'Humans', 'Male', 'Middle Aged', 'Ophthalmologic Surgical Procedures', 'Postoperative Complications', 'Recurrence', 'Risk Factors', 'Tanzania', 'Time Factors', 'Trachoma'] | 15,808,265 | [['M01.060.116.100'], ['B03.440.190.190.190.750'], ['A01.456.505.420.504.421', 'A09.371.337.338', 'A17.360.421'], ['C11.338'], ['F02.830.297.425', 'G11.561.225.425'], ['C17.800.329'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.540'], ['C23.550.767'], ['C23.550.291.937'], ['E05.318.740.6... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Effect of trans-resveratrol on the thrombogenicity and atherogenicity in apolipoprotein E-deficient and low-density lipoprotein receptor-deficient mice. | Resveratrol is one of the major polyphenolics in red wine that has been shown to exert the preventive effects against cardiovascular diseases. The effect of trans-resveratrol (t-RES) administered as an ingredient of the diet on the atherothrombotic tendency was assessed in genetically hypercholesterolemic mice after la... | ['Animals', 'Aortic Diseases', 'Apolipoproteins E', 'Arteriosclerosis', 'Carotid Artery Thrombosis', 'Cholesterol', 'Diet, Atherogenic', 'Dietary Fats', 'Drug Evaluation, Preclinical', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Platelet Aggregation', 'Radiation Injuries, Experimental', 'Receptors, LDL', '... | 15,311,151 | [['B01.050'], ['C14.907.109'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['C14.907.137.126'], ['C10.228.140.300.200.355', 'C14.907.253.123.355', 'C14.907.253.566.206', 'C14.907.355.590.213.206'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['G07.203.650.240.242'],... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Interaction of human myeloperoxidase with nitrite. | EPR (electron paramagnetic resonance) and optical spectroscopy show that human neutrophil myeloperoxidase is converted from ferric high-spin to low-spin by the addition of nitrite. The Soret peak shifts from 429 to 447 nm and new peaks appear in the visible region at 573 and 627 nm; the EPR g-values change from 6.84, 5... | ['Chlorides', 'Electron Spin Resonance Spectroscopy', 'Ferric Compounds', 'Humans', 'Neutrophils', 'Nitrites', 'Peroxidase', 'Spectrophotometry'] | 1,333,417 | [['D01.210.450.150', 'D01.248.497.158.215'], ['E05.196.867.519.274'], ['D01.490.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382.680.689'], ['D01.248.497.158.635', 'D01.625.600.600', 'D02.633'], [... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Concentrations of carbohydrates and lipids of guinea pigs after five days starvation. | The concentrations of serum total lipids, cholesterol and triglycerides of guinea pigs were determined under normal conditions and after 5 days fasting. Serum glucose and liver glycogen levels were also estimated under both conditions. The amounts of serum total lipids and cholesterol were significantly increased as a ... | ['Animals', 'Blood Glucose', 'Carbohydrate Metabolism', 'Cholesterol', 'Guinea Pigs', 'Lipids', 'Liver Glycogen', 'Starvation', 'Triglycerides'] | 2,876,829 | [['B01.050'], ['D09.947.875.359.448.500'], ['G02.111.158', 'G03.191'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['B01.050.150.900.649.313.992.550'], ['D10'], ['D05.750.078.562.388.518', 'D09.698.365.388.518'], ['C18.654.521.750'], ['D10.351.801']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genetic differences in hypothalamic-pituitary-adrenal axis responsiveness to acute ethanol and acute ethanol withdrawal. | There is a growing body of evidence suggesting that corticosteroids contribute to the increased neural excitability observed during ethanol withdrawal. In the present study, this was further investigated using mouse strains which differ in ethanol withdrawal severity. DBA/2 (DBA) mice were found to display more severe ... | ['Adrenocorticotropic Hormone', 'Animals', 'Corticosterone', 'Ethanol', 'Handling, Psychological', 'Hypothalamo-Hypophyseal System', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred DBA', 'Pituitary-Adrenal System', 'Seizures', 'Substance Withdrawal Syndrome'] | 1,320,985 | [['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['B01.050'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['D02.033.375'], ['F01.658.556'], ['A06.688.35... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Hepatic microsomal delta 6 and delta 5 desaturations of linoleic acid in lactating rats fed with a low-protein diet supplemented or not with methionine]. | In the lactating rat, a low protein diet (8% casein) decreases strongly liver microsomal delta 6 and delta 5 desaturase activities. The supplementation of the diet with 0.4% methionine improves partly delta 6 desaturase activity but has no effect on delta 5 desaturase activity. | ['Animals', 'Dietary Proteins', 'Fatty Acid Desaturases', 'Female', 'Lactation', 'Linoleic Acids', 'Methionine', 'Microsomes, Liver', 'Pregnancy', 'Rats'] | 3,138,002 | [['B01.050'], ['D12.776.256', 'G07.203.300.428', 'J02.500.428'], ['D08.811.682.690.708.392'], ['G08.686.523', 'G08.686.702.500'], ['D10.251.355.310.515', 'D10.251.355.343.500'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.166.676'], ['A11.284.835.540.541'], ['G08.686.784.769'], ['B01.050.150.900.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Oxidation of xenobiotics by plant microsomes, a reconstituted cytochrome P450 system and peroxidase: a comparative study. | The microsomal fraction from tulip bulbs (Tulipa fosteriana, L.) contains cytochrome P450 (CYP3, EC 1.14.14.1) and peroxidase (EC 1.11.1.7.) enzymes catalyzing the NADPH--and hydrogen peroxide--dependent oxidation of the xenobiotic substrates, N-nitrosodimethylamine (NDMA), N-nitrosomethylaniline (NMA), aminopyrine and... | ['Cytochrome P-450 Enzyme System', 'Microsomes', 'Oxidation-Reduction', 'Peroxidases', 'Plants', 'Xenobiotics'] | 10,897,475 | [['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['A11.284.835.540'], ['G02.700', 'G03.295.531'], ['D08.811.682.732'], ['B01.650'], ['D26.969']] | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficacy of oral ciprofloxacin plus rifampin for treatment of malignant external otitis. | Malignant external otitis is an invasive pseudomonal infection characteristically afflicting the elderly patient with diabetes mellitus. Therapy has traditionally consisted of the long-term administration of combination parenteral antibiotics, but morbidity and mortality remain substantial despite this therapy. We trea... | ['Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Blood Sedimentation', 'Ciprofloxacin', 'Diabetes Complications', 'Drug Synergism', 'Drug Therapy, Combination', 'Female', 'Humans', 'Male', 'Middle Aged', 'Otitis Externa', 'Pseudomonas Infections', 'Pseudomonas aeruginosa', 'Recurrence', 'Rifampin'] | 2,504,254 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['E01.370.225.625.125', 'E05.200.625.125'], ['D03.633.100.810.835.322.186'], ['C19.246.099'], ['G07.690.773.968.477'], ['E02.319.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C09.218.705.496'], ['C01.150.252.400.739... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Topographical evaluation on decentration of orthokeratology lenses]. | OBJECTIVE: To evaluate the degree and correlative factors of decentration of orthokeratology lenses and its effect on the visual function.METHODS: Two different kinds of orthokeratology lenses were fitted to 270 eyes of 135 patients [initial mean refractive error: (-3.98 +/- 1.51) D]. Humphery Instruments ATLAS 8.0 was... | ['Adolescent', 'Adult', 'Child', 'Corneal Topography', 'Female', 'Humans', 'Male', 'Myopia', 'Orthomolecular Therapy', 'Refraction, Ocular'] | 12,895,361 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['E01.370.380.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.744.636'], ['E02.319.630', 'F04.570.400'], ['E01.370.380.850.700', 'G01.590.775', 'G14.760']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Deeply infiltrating endometriosis: evaluation of retro-cervical space on MRI after vaginal opacification. | OBJECTIVES: To prospectively investigate diagnostic value and tolerability of MRI after intra-vaginal gel opacification for diagnosis and preoperative assessment of deeply infiltrating endometriosis.METHODS: Sixty-three women with clinical suspicion of deeply infiltrating endometriosis were previously examined with tra... | ['Adult', 'Artifacts', 'Endometriosis', 'Female', 'Humans', 'Image Enhancement', 'Magnetic Resonance Imaging', 'Middle Aged', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Subtraction Technique', 'Vagina', 'Vaginal Creams, Foams, and Jellies'] | 21,813,257 | [['M01.060.116'], ['E05.047'], ['C13.351.500.163'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.600.350', 'L01.224.308.380'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Inhibition of receptor binding stabilizes Newcastle disease virus HN and F protein-containing complexes. | Receptor binding of paramyxovirus attachment proteins and the interactions between attachment and fusion (F) proteins are thought to be central to activation of the F protein activity; however, mechanisms involved are unclear. To explore the relationships between Newcastle disease virus (NDV) HN and F protein interacti... | ['Animals', 'Cell Line', 'Chick Embryo', 'HN Protein', 'Immunoprecipitation', 'Membrane Fusion', 'Newcastle disease virus', 'Receptors, Cell Surface', 'Transfection', 'Viral Fusion Proteins'] | 16,501,098 | [['B01.050'], ['A11.251.210'], ['A13.350.150', 'A16.331.200'], ['D12.776.964.970.880.350', 'D23.050.327.461.350'], ['E05.196.150.639', 'E05.478.605'], ['G04.575'], ['B04.820.480.937.600.650.070.600'], ['D12.776.543.750'], ['E05.393.350.810', 'G05.728.860'], ['D12.776.543.512.500', 'D12.776.964.970.880.910']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Are Canadian women achieving a fit pregnancy? A pilot study. | OBJECTIVES: Canadian recommendations exist for energy intake (EI), physical activity (PA) and gestational weight gain (GWG) to help pregnant women avoid excessive GWG and attain "fit pregnancies". Our objectives were: 1) to measure daily EI, PA and GWG to observe whether pregnant women were meeting recommendations, 2) ... | ['Adult', 'Analysis of Variance', 'Body Mass Index', 'Canada', 'Energy Intake', 'Energy Metabolism', 'Feeding Behavior', 'Female', 'Health Status Indicators', 'Health Surveys', 'Humans', 'Logistic Models', 'Mental Recall', 'Odds Ratio', 'Perinatal Care', 'Physical Fitness', 'Pilot Projects', 'Pregnancy', 'Surveys and Q... | 20,364,546 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['Z01.107.567.176'], ['G07.203.650.240.340'], ['G03.295'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['E05.318.308.980.438.475',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A predictive index for the diagnosis of cirrhosis in hepatitis C based on clinical, laboratory, and ultrasound findings. | OBJECTIVE: To develop and validate a non-invasive index to predict the presence of cirrhosis in patients with chronic hepatitis C on the basis of clinical, laboratory, and ultrasound findings.MATERIALS AND METHODS: Data from the complete history and physical examination, serologic studies, liver ultrasound, and liver b... | ['Adult', 'Age Factors', 'Aged', 'Biomarkers', 'Epidemiologic Methods', 'Female', 'Hepatitis C, Chronic', 'Humans', 'Liver Cirrhosis', 'Liver Function Tests', 'Male', 'Middle Aged', 'Physical Examination', 'Platelet Count', 'Prognosis', 'Prothrombin Time', 'Ultrasonography, Doppler, Color'] | 16,357,620 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['D23.101'], ['E05.318', 'N06.850.520'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.552.380.350.120', 'C06.552.380.705.440.120'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.3... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ethanol-induced inhibition of glucose transport across the isolated brush-border membrane of hamster jejunum. | Acute exposure of jejunal mucosa to ethanol has been reported to produce a depression of transmural glucose transport across this organ in vitro and in vivo. In an attempt to understand the mechanism of action of ethanol on intestinal transport, in the present study we have investigated the effect of ethanol on glucose... | ['Animals', 'Biological Transport', 'Cell Membrane', 'Cell Membrane Permeability', 'Cricetinae', 'Ethanol', 'Glucose', 'In Vitro Techniques', 'Jejunum', 'Mannose', 'Membrane Proteins', 'Mesocricetus', 'Microvilli', 'Sodium'] | 7,460,705 | [['B01.050'], ['G03.143'], ['A11.284.149'], ['G03.143.335', 'G04.175'], ['B01.050.150.900.649.313.992.635.075.250'], ['D02.033.375'], ['D09.947.875.359.448'], ['E05.481'], ['A03.556.124.684.500', 'A03.556.249.750'], ['D09.947.875.359.588'], ['D12.776.543'], ['B01.050.150.900.649.313.992.635.075.250.500'], ['A11.284.180... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Levonorgestrel concentrations during 7 years of continuous use of Jadelle contraceptive implants. | Serum levonorgestrel concentrations were assayed in a multicenter, 7-year study of 199 users of Jadelle rod implants. We examined drug levels, patterns of changes, factors affecting drug levels, and concentrations at which pregnancies occurred. Mean levonorgestrel concentrations declined from 435 pg/mL at 1 month of us... | ['Adolescent', 'Adult', 'Age Factors', 'Analysis of Variance', 'Blood Specimen Collection', 'Body Weight', 'Contraceptive Agents, Female', 'Drug Implants', 'Female', 'Humans', 'Levonorgestrel', 'Pregnancy', 'Pregnancy Rate', 'Regression Analysis', 'Time Factors'] | 11,535,213 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E01.370.225.998.110', 'E04.665.150', 'E05.200.998.110'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Laparoscopic spermatic vein ligation]. | Between December 1991 and November 1995 a total of 231 patients underwent laparoscopic varix ligation in our department. The laparoscopic varicocelectomy offers a lower rate of morbidity, allows for microscopic dissection with preservation of the spermatic artery and is amenable to bilateral ligation without a second i... | ['Adult', 'Child', 'Humans', 'Infertility, Male', 'Laparoscopes', 'Ligation', 'Male', 'Microsurgery', 'Surgical Instruments', 'Treatment Outcome', 'Ultrasonography, Doppler, Color', 'Varicocele'] | 8,711,824 | [['M01.060.116'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365.700'], ['E07.230.220.520', 'E07.858.240.520'], ['E04.426'], ['E04.494', 'E05.591.580'], ['E07.858.700'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['E01.370.350.850.850.850.850'], ['C12.294.936', '... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Effect of Continuous Positive Airway Pressure on Cardiovascular Biomarkers: The Sleep Apnea Stress Randomized Controlled Trial. | BACKGROUND: Although existing research highlights the relationship of OSA and cardiovascular disease, the effect of OSA treatment on cardiovascular biomarkers remains unclear. We evaluated the effect of OSA treatment on oxidative stress/inflammation measures.METHODS: We conducted a parallel, randomized controlled trial... | ['Adult', 'Biomarkers', 'Cardiovascular Diseases', 'Continuous Positive Airway Pressure', 'F2-Isoprostanes', 'Female', 'Humans', 'Inflammation', 'Male', 'Middle Aged', 'Oxidative Stress', 'Peroxidase', 'Receptors, Interleukin-6', 'Risk Factors', 'Sleep Apnea, Obstructive', 'Statistics as Topic'] | 26,997,243 | [['M01.060.116'], ['D23.101'], ['C14'], ['E02.041.625.790.259', 'E02.880.820.790.259'], ['D10.251.355.255.100.375.500', 'D10.251.355.310.166.775.500', 'D10.251.355.411.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.470'], ['M01.060.116.630'], ['G03.673', 'G07.775.750'], ['D08.811.682.732.700'], ['D12... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[The two ozone problems: too much in the troposphere, too little in the stratosphere]. | Trends analysis based on the long-term Swiss ozone measurements from Arosa and Payerne operationally performed by the Swiss Meteorological Institute are presented. These measurement include stratospheric ozone (approximately 90% of total ozone) and tropospheric ozone. The total ozone measurements from Arosa, the world ... | ['Atmosphere', 'Environmental Pollutants', 'Fluorocarbons', 'Meteorological Concepts', 'Oxidants, Photochemical', 'Ozone'] | 1,546,226 | [['G16.500.275.063', 'N06.230.300.100'], ['D27.888.284'], ['D02.455.526.510.435'], ['G16.500.750', 'N06.230.300'], ['D27.720.642.631', 'D27.888.569.540.631'], ['D01.362.670.600']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
In seedlings of Pinus radiata, jasmonic acid and auxin are differentially distributed on opposite sides of tilted stems affecting lignin monomer biosynthesis and composition. | Plants respond to the loss of vertical growth re-orientating their affected organs. In trees, this phenomenon has received the scientific attention due to its importance for the forestry industry. Nowadays it is accepted that auxin distribution is involved in the modulation of the tilting response, but how this distrib... | ['Cyclopentanes', 'Gene Expression Regulation, Plant', 'Indoleacetic Acids', 'Lignin', 'Oxylipins', 'Phylogeny', 'Pinus', 'Plant Growth Regulators', 'Plant Proteins', 'Plant Stems', 'Real-Time Polymerase Chain Reaction', 'Seedlings', 'Sequence Analysis, DNA'] | 30,576,980 | [['D02.455.426.392.368.450'], ['G05.308.375'], ['D03.066.288', 'D03.633.100.473.404'], ['D05.750.078.562.180.515', 'D05.750.078.687', 'D20.538', 'D25.720.099.687', 'J01.637.051.720.099.687'], ['D10.251.355.645'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['B01.650.940.800.575.912.625.875.777'], ['D27.505.696.377.760']... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Waist circumference is an independent correlate of errors in self-reported BMI. | Although there are issues of reporting bias surrounding the use of self-reported BMI, it is frequently the method employed to establish the prevalence of obesity. The goal of this study was to assess whether, independently of measured BMI, waist circumference (WC) was associated with the magnitude of the difference bet... | ['Adolescent', 'Adult', 'African Americans', 'Aged', 'Bias', 'Body Mass Index', 'European Continental Ancestry Group', 'Female', 'Humans', 'Linear Models', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Obesity', 'Prevalence', 'Self Report', 'Waist Circumference', 'Young Adult'] | 20,725,063 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['N05.715.350.150', 'N06.850.490.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.686.508.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.50... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Modeling left ventricular dynamics using a switched system approach based on a modified atrioventricular piston unit. | The contribution of the longitudinal atrioventricular plane displacement to ventricular pumping has drawn more and more attentions. In this paper, differential equations of the left ventricle (LV) are derived via the atrioventricular piston concept. The contribution of left ventricular radial function to blood flow was... | ['Atrial Function', 'Biomechanical Phenomena', 'Hemodynamics', 'Models, Cardiovascular', 'Ventricular Function, Left'] | 30,554,979 | [['G09.330.040'], ['G01.154.090', 'G01.374.089'], ['G09.330.380'], ['E05.599.395.161'], ['G09.330.955.800']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Long-term outcome after pulmonary retransplantation. | OBJECTIVE: Bronchiolitis obliterans syndrome has become the most limiting factor for long-term outcome after lung transplantation. Redo lung transplantation was performed for end-stage bronchiolitis obliterans syndrome. Long-term outcome was compared with that after primary lung transplantation as well as with other in... | ['Adolescent', 'Adult', 'Aged', 'Bronchiolitis Obliterans', 'Cause of Death', 'Female', 'Humans', 'Lung Transplantation', 'Male', 'Middle Aged', 'Quality of Life', 'Reoperation', 'Respiration, Artificial', 'Survival Analysis', 'Treatment Outcome'] | 16,872,970 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C08.127.446.135.140', 'C08.381.495.146.135.140'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.928.600.495', 'E04.936.450.495'], ['M01.060... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
An Exceptionally Facile Two-Step Structural Isomerization and Detoxication via a Water-Assisted Double Lossen Rearrangement. | N-hydroxyphthalimide (NHPI), which is best known as an organocatalyst for efficient C-H activation, has been found to be oxidized by quinoid compounds to its corresponding catalytically active nitroxide-radical. Here, we found that NHPI can be isomerized into isatoic anhydride by an unusually facile two-step method usi... | ['Chloranil', 'Chromatography, High Pressure Liquid', 'DNA Damage', 'Electron Spin Resonance Spectroscopy', 'Hydrolysis', 'Hydroxylation', 'Isomerism', 'Isotope Labeling', 'Oxygen Isotopes', 'Phthalimides', 'Plasmids', 'Spectrometry, Mass, Electrospray Ionization', 'Water'] | 28,008,985 | [['D02.806.250.210'], ['E05.196.181.400.300'], ['G05.200'], ['E05.196.867.519.274'], ['G02.380'], ['G02.111.385', 'G02.607.348', 'G03.425'], ['G02.111.570.685', 'G02.607.445'], ['E05.522'], ['D01.268.185.550.500', 'D01.362.670.300', 'D01.496.625'], ['D02.241.223.805.810', 'D02.478.600', 'D03.633.100.513.750'], ['G05.36... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Follow-up among women with an abnormal mammogram in an HMO: is it complete, timely, and efficient? | OBJECTIVE: To describe the extent to which women with seriously abnormal mammograms complete indicated follow-up, the timeliness of this follow-up, and variations in the pattern of use of diagnostic procedures.STUDY DESIGN: Retrospective chart review.PATIENTS AND METHODS: Ninety-two women enrolled in a single urban hea... | ['Adult', 'African Americans', 'Aged', 'Breast Neoplasms', 'Continuity of Patient Care', 'Female', 'Health Care Costs', 'Health Maintenance Organizations', 'Humans', 'Logistic Models', 'Mammography', 'Medicaid', 'Michigan', 'Middle Aged', 'Multivariate Analysis', 'Patient Acceptance of Health Care', 'Poverty', 'Retrosp... | 11,184,666 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['N03.219.151.400', 'N05.300.375'], ['N03.219.521.576.343.800.400', 'N03.219.521.576.343.925.400', 'N04.452.758.244.425', 'N04.590.374.410.400... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Hemodynamic effects of methadone and dihydrocodeine in overdose. | BACKGROUND: Opioid overdose is an increasing health problem worldwide. The cardiovascular toxicity of opioids contributes to morbidity and mortality in overdose but the hemodynamic effects of opioids reported in animal and human studies are contradictory.METHODS: We performed a prospective observational study of patien... | ['Acetaminophen', 'Adult', 'Analgesics, Opioid', 'Blood Pressure', 'Codeine', 'Drug Overdose', 'Female', 'Hemodynamics', 'Humans', 'Male', 'Methadone', 'Middle Aged', 'Oxygen', 'Prospective Studies'] | 17,852,162 | [['D02.065.199.092.040', 'D02.092.146.113.092.040'], ['M01.060.116'], ['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D03.132.577.249.562.149', 'D03.605.497.607.204', 'D03.633.400.686.607.204', 'D... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tespa1 | Thymocyte-expressed, positive selection-associated 1 (Tespa1) plays an important role in both T cell receptor (TCR)-driven thymocyte development and in the FcåRI-mediated activation of mast cells. Herein, we show that lack of Tespa1 does not impair B cell development but dampens the in vitro activation and proliferatio... | ['Adaptor Proteins, Signal Transducing', 'Animals', 'Arthritis, Experimental', 'Autoimmunity', 'B-Lymphocytes', 'CD40 Antigens', 'Calcium', 'Collagen', 'Germinal Center', 'Lymphocyte Activation', 'Mice', 'Mice, Inbred C57BL', 'Mice, Knockout', 'Phospholipase C gamma', 'Phosphorylation', 'Signal Transduction', 'T-Lympho... | 29,867,947 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['B01.050'], ['C05.550.114.015', 'E05.598.500.249'], ['G12.450.192'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D12.776.465.750', 'D12.776.543.750.705.852.760.097', 'D23.050.301.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Occurrence of oxidized metabolites of arachidonic acid esterified to phospholipids in murine lung tissue. | Isolation and characterization of murine pulmonary phospholipids revealed the normal occurrence of 10 isobaric eicosanoids corresponding to the incorporation of one oxygen atom into the arachidonate esterified to glycerophospholipids. Lungs from mice were removed and lipids were extracted and then separated into free c... | ['Animals', 'Arachidonic Acid', 'Chromatography, High Pressure Liquid', 'Eicosanoids', 'Esters', 'Isomerism', 'Lipoxygenase', 'Lung', 'Mass Spectrometry', 'Mice', 'Mice, Inbred Strains', 'Oxidation-Reduction', 'Oxygen', 'Peroxides', 'Phosphatidic Acids', 'Prostaglandin-Endoperoxide Synthases', 'tert-Butylhydroperoxide'... | 9,735,144 | [['B01.050'], ['D10.251.355.255.100.100', 'D10.251.355.310.166.100'], ['E05.196.181.400.300'], ['D10.251.355.255', 'D23.469.050.175'], ['D02.241.400'], ['G02.111.570.685', 'G02.607.445'], ['D08.811.682.690.416.583.625', 'D12.776.556.579.374.568.750'], ['A04.411'], ['E05.196.566'], ['B01.050.150.900.649.313.992.635.505.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Analysis of the binding sites of chromium to DNA and protein in vitro and in intact cells. | Previous studies have examined Cr(III), or CrO4 reduced to Cr(III), binding in vitro to DNA. However, there have been few studies examining chromate binding to DNA in intact cells. Treatment of intact cells with chromate (Na2(51)CrO4) resulted in chromium (Cr) binding to DNA. The binding of Cr to DNA was much more stab... | ['Amino Acids', 'Binding Sites', 'Chromium', 'Cross-Linking Reagents', 'DNA', 'DNA-Binding Proteins'] | 1,473,242 | [['D12.125'], ['G02.111.570.120'], ['D01.268.556.175', 'D01.268.956.124', 'D01.552.544.175'], ['D27.720.470.410.210'], ['D13.444.308'], ['D12.776.260']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Value of the normal chest x-ray in the anamnestic and clinical suspicion of traumatic aortic rupture]. | A retrospective study of plain radiographic findings in 11 patients with traumatic rupture of the aorta was conducted, and the results compared with the incidence of numerous chest x-rays signs previously described in 294 cases of angiographically proven thoracic aorta dissection. It is concluded that positive plain ra... | ['Aorta, Thoracic', 'Aortic Rupture', 'Aortography', 'Humans', 'Retrospective Studies', 'Thoracic Injuries', 'Wounds, Nonpenetrating'] | 6,401,655 | [['A07.015.114.056.372'], ['C14.907.055.185.125', 'C14.907.055.239.175', 'C14.907.109.139.175', 'C26.761.125'], ['E01.370.350.700.060.070', 'E01.370.370.050.070'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.... | ['Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Isolation of Salmonella from meat samples and characterization by enterobacterial repetitive intergenic consensus-polymerase chain reaction and antibiotics test. | Salmonella is one of the most important foodborne pathogens associated with severe diseases in animals and humans. Meat samples are considered as one of the main sources of Salmonella infections. Consequently, the survey of Salmonella contamination in meat samples is of outmost importance for the control and prevention... | ['Animals', 'Cattle', 'Chickens', 'DNA, Bacterial', 'Drug Resistance, Microbial', 'Genotype', 'Multiple Endocrine Neoplasia Type 1', 'Polymerase Chain Reaction', 'Salmonella', 'Swine'] | 21,443,444 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['D13.444.308.212'], ['G06.225', 'G07.690.773.984.269'], ['G05.380'], ['C04.588.322.400.500', 'C04.651.600.500', 'C04.700.630.500', 'C16.320.700.630.500', 'C19.344.400.500'], ['E05.393.620.500'], ['B03... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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