Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Day-Ahead PM2.5 | Accurate PM2.5 concentration forecasting is crucial for protecting public health and atmospheric environment. However, the intermittent and unstable nature of PM2.5 concentration series makes its forecasting become a very difficult task. In order to improve the forecast accuracy of PM2.5 concentration, this paper propo... | ['Air Pollutants', 'Algorithms', 'China', 'Forecasting', 'Humans', 'Models, Theoretical', 'Particulate Matter'] | 28,704,955 | [['D27.888.284.101'], ['G17.035', 'L01.224.050'], ['Z01.252.474.164'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['D20.633']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 |
Laparoscopic approach for rectosigmoidian resection in children. | Abdominoperineal approach for rectosigmoidian resection,first imagined and performed in 1948 by Orwar Swenson,was the surgical technique that opened the pathway in the treatment of congenital megacolon (1). B. Duhamel (1956) and F. Soave (1964) intended to correct the postoperative complications appeared after the Duha... | ['Child', 'Hirschsprung Disease', 'Humans', 'Laparoscopy', 'Treatment Outcome'] | 24,524,481 | [['M01.060.406'], ['C06.198.439', 'C06.405.469.158.701.439', 'C16.131.314.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Mechanisms of increased intestinal [51Cr]EDTA absorption during experimental colitis in the rat. | Experimental colitis was induced in the rat, by ethanol-oxazolone injections into the distal colon, resulting in diarrhea together with edema, ulcers, and cell infiltration in the exposed colon. Colitic rats showed an elevated urinary recovery of the permeability marker [51Cr]EDTA after intragastric feeding, 19 +/- 10%... | ['Animals', 'Chromium Radioisotopes', 'Colitis', 'Colon', 'Edetic Acid', 'Ethanol', 'Female', 'In Vitro Techniques', 'Intestinal Absorption', 'Ovalbumin', 'Oxazolone', 'Rats', 'Rats, Sprague-Dawley'] | 7,956,599 | [['B01.050'], ['D01.268.556.175.500.349', 'D01.268.956.124.500.349', 'D01.496.212.349', 'D01.496.749.213', 'D01.552.544.175.500.349'], ['C06.405.205.265', 'C06.405.469.158.188'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['D02.092.782.258.368.250', 'D02.241.081.018.253'], ['D02.033.375'], ['E05.481'], ['G03.015.5... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The role of the chorda tympani nerve in the activation of the rat hypothalamic histaminergic system by leptin. | A possible pathway through which leptin activates the histaminergic system was studied using in vivo microdialysis in rats. Intraperitoneal injection of leptin (1.3 mg/kg) caused a significant increase in hypothalamic histamine release, however, its intracerebroventricular injection (10 microg/rat) did not cause any si... | ['Animals', 'Appetite Regulation', 'Chorda Tympani Nerve', 'Denervation', 'Histamine', 'Hypothalamus', 'Leptin', 'Male', 'Neural Pathways', 'Neurons', 'Rats', 'Rats, Wistar', 'Taste', 'Taste Buds'] | 11,207,386 | [['B01.050'], ['G07.203.650.170', 'G07.203.650.390.070.290', 'G10.261.390.070.290'], ['A08.800.800.120.250.120'], ['E04.525.210'], ['D02.092.211.215.501', 'D02.092.471.440', 'D03.383.129.308.373', 'D23.469.050.300'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['D06.472.699.042.500', 'D12.644.276.024.500', 'D12... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Regulation of hematopoiesis in vitro by alloreactive natural killer cell clones. | Natural killer (NK) cells lyse autologous and allogeneic target cells even in the absence of major histocompatibility complex (MHC) class I antigens on the target cells. Recently, however, human allospecific NK cell clones have been generated that recognize at least five distinct specificities inherited recessively and... | ['Cell Line', 'Clone Cells', 'Hematopoiesis', 'Hematopoietic Stem Cells', 'Humans', 'Immunophenotyping', 'Interferon-gamma', 'Killer Cells, Natural', 'Tumor Necrosis Factor-alpha'] | 8,459,206 | [['A11.251.210'], ['A11.251.353'], ['G04.152.825', 'G09.188.343'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.812.447', 'E05.200.812.447', 'E05.478.594.450'], ['D12.644.276.374.440.893', 'D12.644.276.374.480.615.350', 'D12.776.467.374.440.893', 'D12... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identification of bacteriophage T4-specific precursor tRNA by using a host mutant defective in the methylation of tRNA. | A mutant of Escherichia coli K-12 that is defective in the synthesis of 5-methyluridine (ribothymidine) in tRNA was used to identify precursors to phage T4-specific tRNA. The precursor molecules, isolated by gel filtration, were more than twice the size of tRNA. This method is suitable for isolation of rather large amo... | ['Coliphages', 'Escherichia coli', 'Methods', 'Methylation', 'Mutation', 'Nucleic Acid Precursors', 'RNA, Transfer', 'RNA, Viral', 'Uridine'] | 1,099,234 | [['B04.123.205'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E05.581'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['G05.365.590'], ['D13.400'], ['D13.444.735.757'], ['D13.444.735.828'], ['D03.383.742.680.852', 'D13.570.685.852', 'D13.570.800.892']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Expression of miR-126/miR-126* in hepatocelluar carcinoma and its correlation with clinical outcomes]. | OBJECTIVE: To investigate the expression of miR-126/miR-126* in hepatocellular carcinoma (HCC) tissues and its clinical significance.METHODS: The expressions of miR-126/miR-126* in the tumor tissues and non-cancer tissues from 74 HCC cases were detected using real-time quantitative PCR. The correlation between miR-126/... | ['Carcinoma, Hepatocellular', 'Down-Regulation', 'Humans', 'Liver Neoplasms', 'MicroRNAs', 'Neoplasm Recurrence, Local', 'Real-Time Polymerase Chain Reaction'] | 25,345,948 | [['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['C04.6... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Front-loading rt PA thrombolytic therapy in central or venous branch occlusions of the retina]. | UNLABELLED: Although central retinal vein occlusion and branch retinal vein occlusion are among the most common vascular disorders affecting the retina, there is a great deal of confusion about their management. In view of the histopathological features of ischemic retinal vein occlusions, the use of fibrinolytic agent... | ['Adult', 'Aged', 'Drug Administration Schedule', 'Drug Therapy, Combination', 'Female', 'Heparin', 'Humans', 'Infusions, Intravenous', 'Male', 'Middle Aged', 'Recombinant Proteins', 'Retinal Vein Occlusion', 'Thrombolytic Therapy', 'Tissue Plasminogen Activator'] | 8,086,742 | [['M01.060.116'], ['M01.060.116.100'], ['E02.319.283'], ['E02.319.310'], ['D09.698.373.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['M01.060.116.630'], ['D12.776.828'], ['C11.768.760', 'C14.907.355.830.925.650', 'C14.907.760'], ['E02.319.913'], ['D08.811.277.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Parent-implemented social intervention for toddlers with autism: an RCT. | OBJECTIVES: To compare the effects of two 9-month parent-implemented interventions within the Early Social Interaction (ESI) Project. Both individual-ESI, offered 2 or 3 times per week at home or in the community, and group-ESI, offered once per week in a clinic, taught parents how to embed strategies to support social... | ['Child Development Disorders, Pervasive', 'Community Mental Health Services', 'Education, Nonprofessional', 'Evidence-Based Practice', 'Female', 'Florida', 'Follow-Up Studies', 'Home Care Services', 'Humans', 'Infant', 'Interpersonal Relations', 'Male', 'Michigan', 'Psychotherapy, Group'] | 25,367,544 | [['F03.625.164'], ['F04.408.307', 'N02.421.143.183', 'N02.421.461.232'], ['I02.233'], ['H02.249'], ['Z01.107.567.875.750.350'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.70... | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Long-term amelioration of feline Mucopolysaccharidosis VI after AAV-mediated liver gene transfer. | Mucopolysaccharidosis VI (MPS VI) is caused by deficient arylsulfatase B (ARSB) activity resulting in lysosomal storage of glycosaminoglycans (GAGs). MPS VI is characterized by dysostosis multiplex, organomegaly, corneal clouding, and heart valve thickening. Gene transfer to a factory organ like liver may provide a lif... | ['Animals', 'Bone and Bones', 'Cats', 'Dependovirus', 'Gene Expression Regulation', 'Gene Transfer Techniques', 'Genetic Therapy', 'Genetic Vectors', 'Glycosaminoglycans', 'HEK293 Cells', 'Humans', 'Liver', 'Motor Activity', 'Mucopolysaccharidosis VI', 'N-Acetylgalactosamine-4-Sulfatase', 'Phenotype', 'Treatment Outcom... | 21,119,624 | [['B01.050'], ['A02.835.232', 'A10.165.265'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['B04.280.580.650.170'], ['G05.308'], ['E05.393.350'], ['E02.095.301', 'E05.393.420.301'], ['G05.360.337'], ['D09.698.373'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620']... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Secondary metabolite and mycotoxin production by the Rhizopus microsporus group. | Fast-growing Zygomycetes, most notably Rhizopus oligosporus, are traditionally used in many food fermentations, for example, for soybean tempeh production. R. oligosporus is considered to belong to the Rhizopus microsporus group. Certain R. microsporus strains have been reported to produce either the pharmaceutically a... | ['Chromatography, Liquid', 'Fermentation', 'Lactones', 'Macrolides', 'Mass Spectrometry', 'Mycotoxins', 'Oryza', 'Peptides, Cyclic', 'Rhizopus', 'Species Specificity', 'Zea mays'] | 15,740,082 | [['E05.196.181.400'], ['G02.111.158.249', 'G03.191.249'], ['D02.540'], ['D02.540.505', 'D02.540.576.500', 'D04.345.674.500'], ['E05.196.566'], ['D23.946.587'], ['B01.650.940.800.575.912.250.822.616'], ['D04.345.566', 'D12.644.641'], ['B01.300.300.500.800'], ['G16.824'], ['B01.650.940.800.575.912.250.822.966']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The kinetics of a novel cyclic reaction system and its use in the assay of polynucleotide phosphorylase or adenosine diphosphate plus adenosine triphosphate. | 1. A sensitive new method is described for the rapid optical assay of polynucleotide phosphorylase in crude bacterial extracts of low specific activity. 2. The assay is non-linear with time and a quick method for determining the approximate activity by using a nomograph is given. 3. The dependence of the assay on Mg(2+... | ['Adenine Nucleotides', 'Adenosine Triphosphate', 'Azotobacter', 'Kinetics', 'Magnesium', 'Mathematics', 'Nucleotidyltransferases', 'Spectrophotometry'] | 5,637,369 | [['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B03.440.400.425.625.050', 'B03.660.250.580.022'], ['G01.374.661', 'G02.111.490'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['H01.548'], ['D08.811.913.696... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of periodontal treatment in patients with periodontitis and diabetes: systematic review and meta-analysis. | OBJECTIVE: The evidence is inconclusive regarding the effect of periodontal treatment on glycemic control and systemic inflammation in patients with type 2 diabetes (T2D) and periodontitis. To evaluate the effect of scaling and root planing (SRP) on the metabolic control and systemic inflammation of patients with type ... | ['C-Reactive Protein', 'Dental Scaling', 'Diabetes Mellitus, Type 2', 'Glycated Hemoglobin A', 'Humans', 'Periodontitis', 'Publication Bias', 'Root Planing', 'Treatment Outcome'] | 31,939,522 | [['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E06.721.189.350', 'E06.761.227.350'], ['C18.452.394.750.149', 'C19.246.300'], ['D09.400.430.937', 'D12.776.124.400.405.440', 'D12.776.395.381', 'D12.776.422.316.762.380.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.465.714.533'], ['L0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Skin irritation and sensitization potential of oxidative hair dye substances evaluated with in vitro, in chemico and in silico test methods. | Permanent oxidative hair dyes are widely used but their toxicity is not well-established. Here we aimed to evaluate the skin sensitization and irritation of nine hair dye substances (MAP, MRP-N, RS, PAOX, 2,4-DAPE, 2,6-PYR, PPD, Grey HED and PM) permitted for use in EU and Korea, using in vitro and in chemico and in si... | ['Biological Assay', 'Computer Simulation', 'Dermatitis, Allergic Contact', 'European Union', 'Hair Dyes', 'Humans', 'Irritants', 'Oxidants', 'Oxidative Stress', 'Republic of Korea', 'Skin', 'Skin Irritancy Tests'] | 30,213,554 | [['E05.091'], ['L01.224.160'], ['C17.800.174.255.100', 'C17.800.815.255.100', 'C20.543.418.150'], ['I01.615.500.475'], ['D27.720.233.837', 'D27.720.269.430.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.400', 'D27.888.569.300'], ['D27.720.642', 'D27.888.569.540'], ['G03.673', 'G07.775.750'], ['Z01.25... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 |
Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid beta-protein generation. | An unusual intramembranous cleavage of the beta-amyloid precursor protein (APP) by gamma-secretase is the final step in the generation of amyloid beta-peptide (Abeta). Two conserved aspartates in transmembrane (TM) domains 6 and 7 of presenilin (PS) 1 are required for Abeta production by gamma-secretase. Here we report... | ['Amyloid Precursor Protein Secretases', 'Amyloid beta-Peptides', 'Amyloid beta-Protein Precursor', 'Animals', 'Aspartic Acid Endopeptidases', 'Binding Sites', 'CHO Cells', 'Cricetinae', 'Endopeptidases', 'Golgi Apparatus', 'Humans', 'Hydrolysis', 'Membrane Proteins', 'Peptide Fragments', 'Presenilin-1'] | 10,922,078 | [['D08.811.277.656.300.032'], ['D12.644.024', 'D12.776.049.407.249.500', 'D12.776.543.039.500'], ['D12.776.049.407.249', 'D12.776.543.039', 'D12.776.645.468.500', 'D12.776.811.050'], ['B01.050'], ['D08.811.277.656.074.500', 'D08.811.277.656.300.048'], ['G02.111.570.120'], ['A11.251.210.200', 'A11.436.155'], ['B01.050.1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Store-operated Ca2+ Entry Mediated by Orai1 and TRPC1 Participates to Insulin Secretion in Rat â-Cells. | Store-operated Ca(2+) channels (SOCs) are voltage-independent Ca(2+) channels activated upon depletion of the endoplasmic reticulum Ca(2+) stores. Early studies suggest the contribution of such channels to Ca(2+) homeostasis in insulin-secreting pancreatic â-cells. However, their composition and contribution to glucose... | ['Acetylcholine', 'Amino Acid Substitution', 'Animals', 'Calcium', 'Calcium Channels', 'Calcium Signaling', 'Cell Line, Tumor', 'Insulin', 'Insulin Secretion', 'Insulin-Secreting Cells', 'Membrane Glycoproteins', 'Mutation, Missense', 'ORAI1 Protein', 'Rats', 'Stromal Interaction Molecule 1', 'TRPC Cation Channels', 'T... | 26,494,622 | [['D02.092.211.111'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['A11.251.210.190', 'A11.251.860.180'], ['D0... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of amethopterin (methotrexate) on the evolution of pregnancy in rats. | Amethopterin (4-amino-N-10-methyl-glutamic acid) was given to pregnant rats in varying doses at different periods of gestation to evaluate its effects upon both the mother and the fetoplacental unit. The maternal organism is more sensitive to this drug at days 14 to 17 than at a larger stage of gestation. When administ... | ['Abortifacient Agents', 'Animals', 'Body Weight', 'Female', 'Fetal Death', 'Fetus', 'Gestational Age', 'Hypertrophy', 'Lethal Dose 50', 'Methotrexate', 'Organ Size', 'Placenta', 'Pregnancy', 'Pregnancy, Animal', 'Rats'] | 1,168,956 | [['D27.505.696.875.131', 'D27.505.954.705.131'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C13.703.223', 'C23.550.260.585'], ['A16.378'], ['G07.345.500.325.235.968', 'G08.686.320'], ['C23.300.775'], ['E05.940.402', 'G07.225.500', ... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Photodecomposition of a new 1,4-dihydropyridine: furnidipine. | The photodecomposition of new 1,4-dihydropyridine, furnidipine (CRE-319); [2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-tetrahydrofurfuryl 5-methyl diester) was studied by voltammetric, UV-vis spectrophotometric, and HPLC technique with three different light conditions (artificial daylight... | ['Calcium Channel Blockers', 'Chromatography, High Pressure Liquid', 'Chromatography, Thin Layer', 'Dihydropyridines', 'Drug Stability', 'Half-Life', 'Light', 'Magnetic Resonance Spectroscopy', 'Photochemistry', 'Polarography', 'Spectrophotometry, Infrared', 'Spectrophotometry, Ultraviolet', 'Ultraviolet Rays'] | 8,046,604 | [['D27.505.519.562.249', 'D27.505.696.260.500', 'D27.505.954.411.192'], ['E05.196.181.400.300'], ['E05.196.181.400.537'], ['D03.383.725.203'], ['E05.916.330'], ['G01.910.405'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G01.750.770.578'], ['E05.196.867.519'], ['H01.181.529.711'], ['E05.196.749', 'E05.30... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Clinical and histopathologic features of antibody-mediated rejection among pediatric renal transplant recipients with preformed vs de novo donor-specific antibodies. | Preformed and de novo donor specific antibodies (pDSA and dnDSA) are risk factors for ABMR. This study compares the effects of pDSA vs dnDSA in pediatric kidney transplant recipients. Sixteen pediatric patients with biopsy-proven ABMR were evaluated. Strong DSA (MFI >10 000) was recorded at transplant, rejection, and f... | ['Adolescent', 'Child', 'Child, Preschool', 'Female', 'Follow-Up Studies', 'Graft Rejection', 'Humans', 'Immunosuppressive Agents', 'Isoantibodies', 'Kidney Transplantation', 'Male', 'Risk Factors'] | 29,159,992 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G12.875.545.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['D12.776.124.486.485.114.664', 'D12.776.124.790.651.114.664', 'D12.776.377.71... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hypothalamic degradation of galanin(1-29) and galanin(1-16): identification and characterization of the peptidolytic products. | The degradation of the neuropeptide galanin(1-29) and its fully active synthetic N-terminal fragment galanin(1-16) in hypothalamic tissue, where these peptides potently affect feeding behaviour, is studied. Galanin(1-29) had a half-life of 100 min while galanin(1-16) had a half-life of 28 min when incubated with a hypo... | ['Amino Acid Sequence', 'Animals', 'Bacitracin', 'Chromatography, High Pressure Liquid', 'Galanin', 'Half-Life', 'Hypothalamus', 'In Vitro Techniques', 'Ligands', 'Male', 'Molecular Sequence Data', 'Peptide Fragments', 'Peptides', 'Protease Inhibitors', 'Rats', 'Rats, Inbred Strains', 'Swine'] | 1,723,638 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D04.345.566.075', 'D12.644.641.075'], ['E05.196.181.400.300'], ['D12.644.400.250', 'D12.776.631.650.250'], ['G01.910.405'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['E05.481'], ['D27.720.470.480'], ['L01.453.245.667'], ['D12.644.541'], ['D12.644'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Three-dimensional holographic vector of atomic interaction field for quantitative structure-activity relationship of Aza-bioisosteres of anthrapyrazoles (Aza-APs). | A newly developed descriptor, three-dimensional holographic vector of atomic interaction field (3D-HoVAIF), is used to describe the chemical structures of Aza-bioisosteres of anthrapyrazoles (Aza-APs). 3D-HoVAIF contains three non-bonded (electrostatic, van der Waals and hydrophobic) factors, which are directly related... | ['Anthracyclines', 'Antibiotics, Antineoplastic', 'Binding Sites', 'Drug Design', 'Drug Interactions', 'Holography', 'Hydrophobic and Hydrophilic Interactions', 'Intercalating Agents', 'Models, Molecular', 'Molecular Structure', 'Quantitative Structure-Activity Relationship', 'Static Electricity'] | 18,243,741 | [['D02.455.426.559.847.562.050', 'D04.615.562.050', 'D09.408.051.059'], ['D27.505.954.248.106'], ['G02.111.570.120'], ['E05.290.500', 'H01.158.703.007.338.500', 'H01.181.466.338.500'], ['G07.690.773.968'], ['E01.370.350.400.500', 'E01.370.350.600.300'], ['G02.409'], ['D27.720.470.410.360'], ['E05.599.595'], ['G02.111.5... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Savings with upgraded performance through improved activated sludge denitrification in the combined activated sludge-biofilter system of the Southpest Wastewater Treatment Plant. | The purpose of the experiments was to increase the rate of activated sludge denitrification in the combined biological treatment system of the Southpest Wastewater Treatment Plant in order to gain savings in cost and energy and improve process efficiency. Initial profile measurements revealed excess denitrification cap... | ['Ammonia', 'Bioreactors', 'Carbon', 'Computer Simulation', 'Hungary', 'Hydrogen-Ion Concentration', 'In Situ Hybridization, Fluorescence', 'Models, Theoretical', 'Nitrates', 'Nitrites', 'Nitrogen', 'Nitrosomonas', 'Oxidation-Reduction', 'Oxygen', 'Sewage', 'Temperature', 'Waste Disposal, Fluid', 'Water Movements', 'Wa... | 18,469,403 | [['D01.362.075', 'D01.625.050'], ['E07.115', 'J01.897.120.115'], ['D01.268.150'], ['L01.224.160'], ['Z01.542.248.495'], ['G02.300'], ['E01.370.225.500.620.670.325.350', 'E01.370.225.750.600.670.325.350', 'E05.200.500.620.670.325.350', 'E05.200.750.600.670.325.350', 'E05.393.285.350', 'E05.393.661.475.350'], ['E05.599']... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
[Reflections of child hospitalization in the life of the familiar attender]. | This is an assistance convergent research, which aimed to investigate the effects of child's hospitalization in the companion family life. It was performed in a hospital located in Goiania-GO, Brazil, where parents of hospitalized children participated in a support group. Data collection occurred from 2010 February to ... | ['Child', 'Child, Hospitalized', 'Family', 'Family Health', 'Family Relations', 'Humans'] | 24,008,698 | [['M01.060.406'], ['M01.643.259'], ['F01.829.263', 'I01.880.853.150'], ['N01.400.300'], ['F01.829.263.370', 'I01.880.853.150.439'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Effect of captopril on prostacyclin and nitric oxide formation in healthy human subjects: interaction with low dose acetylsalicylic acid. | 1. Angiotensin converting enzyme inhibitors have been suggested to act in part by potentiating the stimulatory effect of bradykinin on endothelial prostacyclin and/or nitric oxide (NO) formation. This may give rise to interaction with cyclo-oxygenase inhibiting drugs like acetylsalicylic acid, which is most often used ... | ['Adult', 'Angiotensin-Converting Enzyme Inhibitors', 'Aspirin', 'Blood Pressure', 'Captopril', 'Cross-Over Studies', 'Cyclooxygenase Inhibitors', 'Double-Blind Method', 'Drug Interactions', 'Epoprostenol', 'Female', 'Humans', 'Iodine Radioisotopes', 'Nitric Oxide', 'Radioimmunoassay', 'Stimulation, Chemical'] | 8,971,427 | [['M01.060.116'], ['D27.505.519.389.745.085'], ['D02.455.426.559.389.657.410.595.176'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D12.125.072.401.623.270'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['D27.505.519.389.310', 'D27.505.696.663.850.014.040.500.500', 'D27.505.954.158.030.500', 'D... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Fibular motor nerve conduction studies: Investigating the mechanism for compound muscle action potential amplitude drop with proximal stimulation. | INTRODUCTION: The compound muscle action potential (CMAP) amplitude of extensor digitorum brevis can show a drop with proximal stimulation in normal fibular nerves.METHODS: We assessed the contribution of the far-field potential recorded by the reference electrode (R-CMAP) to the fibular CMAP. Negative R-CMAP amplitude... | ['Action Potentials', 'Adult', 'Biophysics', 'Electric Stimulation', 'Electrodes', 'Electromyography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Neural Conduction', 'Peroneal Nerve', 'Young Adult'] | 25,846,267 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['M01.060.116'], ['H01.158.344', 'H01.671.100'], ['E05.723.402'], ['E07.305.250'], ['E01.370.405.255', 'E01.370.530.255'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.567', 'A10.690.552.500'], ['G07.265.753', 'G11.561.601'], ['A... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Antibiotic prophylaxis for the prevention of recurrent urinary tract infection in children with low grade vesicoureteral reflux: results from a prospective randomized study. | PURPOSE: Antibiotic prophylaxis is given to children at risk for urinary tract infection. However, evidence concerning its effectiveness in grade I to III vesicoureteral reflux is lacking. The objective of this study was to determine whether antibiotic prophylaxis reduces the incidence of urinary tract infection in you... | ['Anti-Infective Agents, Urinary', 'Antibiotic Prophylaxis', 'Disease-Free Survival', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Male', 'Prospective Studies', 'Secondary Prevention', 'Sex Factors', 'Treatment Outcome', 'Trimethoprim, Sulfamethoxazole Drug Combination', 'Urinary Tract Infections', 'Vesico-Urete... | 18,082,208 | [['D27.505.954.122.237', 'D27.505.954.613.056'], ['E02.319.162.150', 'E02.319.703.150'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Psychosocial factors and health perceptions in parents and children who are overweight or obese. | This study examined the relationships among weight status (BMI), health perceptions, and psychosocial characteristics in children, parents, and parent-child dyads. A convenient sample of 114 parent-child dyads participated. All children were overweight or obese. Parents and children completed questionnaires by self-rep... | ['Adult', 'African Americans', 'Body Mass Index', 'Child', 'Female', 'Health Behavior', 'Health Status', 'Health Surveys', 'Hispanic Americans', 'Humans', 'Intention', 'Male', 'Middle Aged', 'Motivation', 'Obesity', 'Overweight', 'Parent-Child Relations', 'Parents', 'Quality of Life', 'Self Concept', 'Surveys and Quest... | 20,057,378 | [['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['M01.060.406'], ['F01.145.488'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The effect of implementing a more comprehensive screening for substance use among pregnant women in North Carolina. | OBJECTIVES: Substance use during pregnancy causes significant morbidity and mortality. Screening for substance use provides opportunity for intervention and treatment, but is often overlooked in prenatal care with today's fiscal climate and preconceived ideas about who uses substances. The purpose of this study was to ... | ['Adult', 'Demography', 'Female', 'Humans', 'Mass Screening', 'North Carolina', 'Pregnancy', 'Pregnancy Complications', 'Random Allocation', 'Substance Abuse Detection', 'Substance-Related Disorders', 'Surveys and Questionnaires'] | 10,746,755 | [['M01.060.116'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438.580', 'N06.850.780.500'], ['Z01.107.567.875.075.475', 'Z01.107.567.875.750.530'], ['G08.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Possibilities of an open magnetic resonance scanner integration in therapy simulation and three-dimensional radiotherapy planning]. | PURPOSE: A system for digital integration of an open MR scanner (0.23 T, Figure 1) in therapy simulation and 3D radiation treatment planning is described.METHOD: MR images were acquired using the body coil and various positioning and immobilization aids. A gradient echo sequence (TR/TE 320 ms/24 ms) was used to create ... | ['Algorithms', 'Carcinoma, Bronchogenic', 'Humans', 'Image Processing, Computer-Assisted', 'Lung Neoplasms', 'Magnetic Resonance Imaging', 'Phantoms, Imaging', 'Radiotherapy Dosage', 'Radiotherapy Planning, Computer-Assisted', 'Systems Integration', 'Tomography, X-Ray Computed'] | 10,356,612 | [['G17.035', 'L01.224.050'], ['C04.588.894.797.520.109.220', 'C08.381.540.140', 'C08.785.520.100.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['E01.370.350.825.500'], ['E07.671'], ['E02.815.639'], ['E02.950.825', 'L01.313.500.750.100.710... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Primary care pediatrics vs. family practice: a nonissue. | As in other areas of the world, in Israel there is an ongoing discussion about who should provide primary health care for children--the family physician or a pediatric specialist. Since the problem should be defined in terms of the health needs of the child, and not in terms of the social groupings of the medical profe... | ['Child', 'Child Health Services', 'Family Practice', 'Humans', 'Israel', 'Pediatrics', 'Primary Health Care'] | 6,885,367 | [['M01.060.406'], ['N02.421.143.130'], ['H02.403.340.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.500.375'], ['H02.403.670'], ['N04.590.233.727']] | ['Named Groups [M]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Does the mechanical work in running change during the VO2 slow component? | PURPOSE: The origin of the slow component is not fully understood. The mechanical hypothesis is one of the potential factors, because an increase in external mechanical work with fatigue was previously reported for a constant velocity run. The purpose of this study was to determine whether a change in mechanical work c... | ['Adult', 'Biomechanical Phenomena', 'Exercise Test', 'Humans', 'Kinetics', 'Muscle Fatigue', 'Oxygen Consumption', 'Pulmonary Gas Exchange', 'Running'] | 12,544,635 | [['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['G11.427.550'], ['G03.680'], ['E01.370.386.700.650', 'G03.143.775.602', 'G09.772.705.760.602'], ['G11.427.410.568.610', 'G11.... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Role of axons in membrane phospholipid synthesis in rat sympathetic neurons. | The axonal synthesis of phospholipids has been demonstrated in compartmented cultures of rat sympathetic neurons. In this model of neuron culture, metabolic events occurring in distal axons were studied independently of those occurring in cell bodies. Using radiolabeled tracers the axonal biosynthesis of the major memb... | ['Animals', 'Antineoplastic Agents', 'Axons', 'Cells, Cultured', 'Choline', 'Membrane Lipids', 'Nerve Tissue Proteins', 'Neurons', 'Phosphatidylcholines', 'Phospholipids', 'Phosphorylcholine', 'Rats', 'Rats, Sprague-Dawley', 'Sympathetic Nervous System'] | 7,566,356 | [['B01.050'], ['D27.505.954.248'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['A11.251'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['D10.570'], ['D12.776.631'], ['A08.675', 'A11.671'], ['D10.570.755.375.760.400.800'], ['D10.570.755'], ['D0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Intestinal angina: percutaneous transluminal angioplasty of the celiac and superior mesenteric arteries. | Percutaneous transluminal angioplasty (PTA) was performed in ten patients with chronic ischemia of the mesenteric arteries and stenoses of the celiac artery and/or the superior mesenteric artery (SMA). PTA was performed on 14 occasions, with attempted dilation of 19 arteries. PTA was technically unsuccessful in two pat... | ['Adult', 'Aged', 'Angioplasty, Balloon', 'Celiac Artery', 'Constriction, Pathologic', 'Female', 'Humans', 'Intestines', 'Ischemia', 'Male', 'Mesenteric Arteries', 'Mesenteric Vascular Occlusion', 'Middle Aged'] | 2,964,677 | [['M01.060.116'], ['M01.060.116.100'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['A07.015.114.207'], ['C23.300.287'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.124'], ['C23.550.513'], ['A07.015.114.565'], ['C06.405.469.675', 'C06.844.550', 'C14.907.137.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Promoting the quality of life in nursing homes: can regulation succeed? | It has been assumed that the best policy for promoting quality of life in nursing homes is direct regulation. In this paper it is argued that if our experience in regulating quality of care is any indication, we may not possess the political will to successfully regulate quality of life. Moreover, from a legal perspect... | ['Cost Control', 'Facility Regulation and Control', 'Jurisprudence', 'Nursing Homes', 'Quality of Life', 'United States'] | 2,614,043 | [['N03.219.151.160'], ['N03.706.280', 'N05.700.300'], ['I01.880.604.583', 'N03.706.535'], ['N02.278.825.610'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['Z01.107.567.875']] | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Geographicals [Z]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Foliar ä15N is affected by foliar nitrogen uptake, soil nitrogen, and mycorrhizae along a nitrogen deposition gradient. | Foliar nitrogen isotope (ä(15)N) composition patterns have been linked to soil N, mycorrhizal fractionation, and within-plant fractionations. However, few studies have examined the potential importance of the direct foliar uptake of gaseous reactive N on foliar ä(15)N. Using an experimental set-up in which the rate of ... | ['Acer', 'Betula', 'Fagus', 'Mycorrhizae', 'Nitrogen', 'Nitrogen Isotopes', 'Quercus', 'Soil', 'Trees'] | 23,070,141 | [['B01.650.940.800.575.912.250.885.056'], ['B01.650.940.800.575.912.250.859.750.200.750'], ['B01.650.940.800.575.912.250.859.750.300.249'], ['A18.400.525', 'A19.690', 'B01.300.655', 'B05.550'], ['D01.268.604', 'D01.362.625'], ['D01.268.604.500', 'D01.362.625.500', 'D01.496.586'], ['B01.650.940.800.575.912.250.859.750.3... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Origin of deficits in the flicker electroretinogram of the cone system in X-linked retinoschisis as derived from response nonlinearities. | The aim of this study was to identify the origin of a high-frequency attenuation in the flicker electroretinogram (ERG) of patients with X-linked retinoschisis (XLRS) through an analysis of nonlinearities in the ERG response. The ERGs of six patients with XLRS and six age-similar control subjects were recorded in respo... | ['Adult', 'Electroretinography', 'Female', 'Genetic Linkage', 'Humans', 'Macular Degeneration', 'Male', 'Middle Aged', 'Photic Stimulation', 'Reference Values', 'Retinal Cone Photoreceptor Cells', 'X Chromosome'] | 11,318,324 | [['M01.060.116'], ['E01.370.380.225', 'E01.370.405.270'], ['G05.348'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.768.585.439'], ['M01.060.116.630'], ['E05.723.729'], ['E05.978.810'], ['A08.675.650.850.625.670.100', 'A08.675.650.915.937.670.100', 'A08.800.950.937.670.100', 'A09.371.729.831.625.670.100', 'A1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Arm motion coupling during locomotion-like actions: an experimental study and a dynamic model. | We studied the coordination of arm movements in standing persons who performed an out-of-phase arm-swinging task while stepping in place or while standing. The subjects were instructed to stop one of the arms in response to an auditory signal while trying to keep the rest of the movement pattern unchanged. A significan... | ['Adolescent', 'Adult', 'Arm', 'Biomechanical Phenomena', 'Female', 'Gait', 'Humans', 'Image Processing, Computer-Assisted', 'Kinesthesis', 'Male', 'Models, Theoretical', 'Motor Activity', 'Muscle, Skeletal', 'Photography', 'Psychomotor Performance', 'Software', 'Walking', 'Young Adult'] | 21,628,725 | [['M01.060.057'], ['M01.060.116'], ['A01.378.800.075'], ['G01.154.090', 'G01.374.089'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['F02.830.816.541.504', 'G11.561.790.541.587'], ['E05.599'], ['F01.145.632', 'G11.427.410.698'], ['A02.633.567', 'A10.... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 |
Different profiles of neuroendocrine cell differentiation evolve in the PC-310 human prostate cancer model during long-term androgen deprivation. | BACKGROUND: Neuroendocrine (NE) cells are androgen-independent cells and secrete growth-modulating peptide hormones via a regulated secretory pathway (RSP). We studied NE differentiation after long-term androgen withdrawal in the androgen-dependent human prostate cancer xenograft PC-310.METHODS: Tumor-bearing nude mice... | ['Androgens', 'Animals', 'Antigens, Nuclear', 'Blotting, Western', 'Cell Cycle Proteins', 'Cell Differentiation', 'Chromogranin A', 'Chromogranins', 'Cyclin-Dependent Kinase Inhibitor p27', 'Growth Substances', 'Humans', 'Immunohistochemistry', 'Male', 'Mice', 'Mice, Nude', 'Mixed Function Oxygenases', 'Multienzyme Com... | 11,870,798 | [['D27.505.696.399.472.161'], ['B01.050'], ['D12.776.660.625', 'D23.050.290'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['D12.776.167'], ['G04.152'], ['D12.776.631.199.249'], ['D12.776.631.199', 'D12.776.811.185'], ['D12.644.360.225.600', 'D12.776.167.187.600'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation of two Salmonella typhi strains with reduced virulence for use in teaching and proficiency testing. | A total of 21 cases of laboratory-acquired typhoid fever associated with teaching and proficiency tests occurred in the United States during a 33-month period, prompting a search for less virulent strains of S. typhi which would be suitable for teaching purposes. Two strains were evaluated which are reported to have re... | ['Agglutination Tests', 'Animals', 'Anti-Bacterial Agents', 'Antigens, Bacterial', 'Bacteriophage Typing', 'Culture Media', 'Evaluation Studies as Topic', 'Freeze Drying', 'Humans', 'Hydrogen Sulfide', 'Mice', 'Microbial Sensitivity Tests', 'Salmonella typhi', 'Teaching Materials'] | 7,107,842 | [['E01.370.225.812.735.050', 'E05.200.812.735.050', 'E05.478.594.760.050'], ['B01.050'], ['D27.505.954.122.085'], ['D23.050.161'], ['E01.370.225.875.150.125.150', 'E05.200.875.150.125.150'], ['D27.720.470.305', 'E07.206'], ['E05.337', 'N05.715.360.335'], ['E01.370.225.500.620.760.160.260', 'E01.370.225.750.600.760.160.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Impact of morphologic characteristics of central pulmonary thromboemboli in massive pulmonary embolism. | STUDY OBJECTIVE: To assess the impact of morphologically different central pulmonary artery thromboemboli in patients with massive pulmonary emboli (MPEs) on short-term outcome.DESIGN: A prospective registry of consecutive patients.SETTING: An 11-bed closed medical ICU at a 860-bed community general hospitalPATIENTS: F... | ['Aged', 'Aged, 80 and over', 'Cardiac Catheterization', 'Cause of Death', 'Critical Care', 'Echocardiography, Transesophageal', 'Female', 'Hospital Mortality', 'Humans', 'Male', 'Middle Aged', 'Prospective Studies', 'Pulmonary Embolism', 'Risk Factors', 'Shock', 'Survival Rate'] | 12,226,042 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.370.380.140', 'E02.148.442', 'E05.157.250'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['E02.760.190', 'N02.421.585.190'], ['E01.370.350.130.750.235', 'E01.370.350.850.220.235', 'E01.370.370.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Reflex responses to combined hip and knee motion in human chronic spinal cord injury. | The relative contributions of hip and knee proprioceptors to the origination of extensor spasms were examined in 11 subjects with chronic spinal cord injury (SCI). Ramp and hold extension and combined hip and knee oscillation movements were imposed to the right leg while the ankle was held in a static position by a cus... | ['Adult', 'Aged', 'Cervical Vertebrae', 'Electromyography', 'Hip Joint', 'Humans', 'Isometric Contraction', 'Knee Joint', 'Middle Aged', 'Muscle Spasticity', 'Proprioception', 'Range of Motion, Articular', 'Reflex', 'Spinal Cord Injuries', 'Thoracic Vertebrae'] | 20,593,325 | [['M01.060.116'], ['M01.060.116.100'], ['A02.835.232.834.151'], ['E01.370.405.255', 'E01.370.530.255'], ['A02.835.583.411'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494.472'], ['A02.835.583.475'], ['M01.060.116.630'], ['C05.651.512', 'C10.597.613.550.550', 'C23.888.592.608.550.550'], ['F02.830.816.54... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of hyperglycemia on the differential expression of insulin and insulin-like growth factor-I receptors in human normal peritoneal and adhesion fibroblasts. | OBJECTIVE: To determine whether the insulin receptor (IR), insulin-like growth factor-I receptor (IGF-IR), and IGF-I are expressed differentially in fibroblasts isolated from normal peritoneal and adhesion tissue before and after 24-hour treatment with increasing glucose concentrations.DESIGN: Prospective experimental ... | ['Cells, Cultured', 'Dose-Response Relationship, Drug', 'Drug Administration Schedule', 'Enzyme-Linked Immunosorbent Assay', 'Fibroblasts', 'Glucose', 'Humans', 'Hyperglycemia', 'Insulin-Like Growth Factor I', 'Peritoneal Diseases', 'Peritoneum', 'RNA, Messenger', 'Receptor, IGF Type 1', 'Receptor, Insulin', 'Reverse T... | 16,962,112 | [['A11.251'], ['G07.690.773.875', 'G07.690.936.500'], ['E02.319.283'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['A11.329.228'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.952'], ['D12.644.276.937.40... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The first Illumina-based de novo transcriptome sequencing and analysis of safflower flowers. | BACKGROUND: The safflower, Carthamus tinctorius L., is a worldwide oil crop, and its flowers, which have a high flavonoid content, are an important medicinal resource against cardiovascular disease in traditional medicine. Because the safflower has a large and complex genome, the development of its genomic resources ha... | ['Biosynthetic Pathways', 'Carthamus tinctorius', 'Computational Biology', 'Flavonoids', 'Flowers', 'Gene Expression Profiling', 'High-Throughput Nucleotide Sequencing', 'Molecular Sequence Annotation', 'Phenotype', 'Transcriptome'] | 22,723,874 | [['G02.111.098', 'G03.493.100'], ['B01.650.940.800.575.912.250.100.181.500'], ['H01.158.273.180', 'L01.313.124'], ['D03.383.663.283.266.450', 'D03.633.100.150.266.450'], ['A18.024.249.500'], ['E05.393.332'], ['E05.393.760.319'], ['E05.393.760.479', 'L01.453.245.667.580'], ['G05.695'], ['G02.111.873.750', 'G05.297.700.7... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of uterine space and fetal sex on conceptus development and in vitro release of progesterone and estrone from regions of the porcine placenta throughout gestation. | Intact (n = 17) and unilaterally hysterectomized-ovariectomized (UHOX, n = 19) gilts were used to study conceptus development and the steroidogenic capability of three regions of the porcine placenta under normal and crowded intrauterine conditions. Gilts were hysterectomized on either Days 30, 50, 70, or 90 of gestati... | ['Animals', 'Embryonic and Fetal Development', 'Estrone', 'Female', 'Fetus', 'Hysterectomy', 'Ovariectomy', 'Placenta', 'Pregnancy', 'Progesterone', 'Sex Characteristics', 'Swine', 'Time Factors', 'Uterus'] | 7,621,680 | [['B01.050'], ['G07.345.500.325', 'G08.686.784.170'], ['D04.210.500.365.415.414', 'D04.210.500.578.502.497', 'D06.472.040.502.497', 'D06.472.334.851.437.996'], ['A16.378'], ['E04.950.300.399'], ['E04.270.282.685', 'E04.950.165.685', 'E04.950.300.680'], ['A16.710'], ['G08.686.784.769'], ['D04.210.500.745.745.654.829', '... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Deficits of motion integration and segregation in patients with unilateral extrastriate lesions. | Functional neuroimaging in human subjects and single cell recordings in monkeys show that several extra-striate visual areas are activated by visual motion. However, the extent to which different types of motion are processed in different regions remains unclear, although neuropsychological studies of patients with cir... | ['Adult', 'Aged', 'Cerebral Infarction', 'Discrimination, Psychological', 'Female', 'Humans', 'Imaging, Three-Dimensional', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Motion Perception', 'Pattern Recognition, Visual', 'Perceptual Disorders', 'Photic Stimulation', 'Psychophysics', 'Visual Cortex'] | 15,975,945 | [['M01.060.116'], ['M01.060.116.100'], ['C10.228.140.300.150.477.200', 'C10.228.140.300.775.200.200', 'C14.907.253.092.477.200', 'C14.907.253.855.200.200', 'C23.550.513.355.250.200', 'C23.550.717.489.250.200'], ['F02.463.593.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'],... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Randomized trial of initial trophic versus full-energy enteral nutrition in mechanically ventilated patients with acute respiratory failure. | OBJECTIVE: Enteral nutrition is provided to mechanically ventilated patients who cannot eat normally, yet the amount of support needed is unknown. We conducted this randomized, open-label study to test the hypothesis that initial low-volume (i.e., trophic) enteral nutrition would decrease episodes of gastrointestinal i... | ['Academic Medical Centers', 'Acute Disease', 'Adult', 'Aged', 'Critical Care', 'Enteral Nutrition', 'Female', 'Follow-Up Studies', 'Hospital Mortality', 'Humans', 'Intensive Care Units', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Nutritional Requirements', 'Parenteral Nutrition', 'Respiration, Artificial', 'Resp... | 21,242,788 | [['N02.278.020'], ['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['E02.760.190', 'N02.421.585.190'], ['E02.421.360', 'E02.642.500.360'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E05.318.308.985.550.400', 'N01.224.935.698.400', 'N06.850.505.400.975.550.400'... | ['Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Glue-Free Stacked Luminescent Nanosheets Enable High-Resolution Ratiometric Temperature Mapping in Living Small Animals. | In this paper, a microthermograph, temperature mapping with high spatial resolution, was established using luminescent molecules embedded ultrathin polymeric films (nanosheets), and demonstrated in a living small animal to map out and visualize temperature shift due to animal's muscular activity. Herein, we report supe... | ['Adhesives', 'Animals', 'Luminescence', 'Thermography', 'Thermometers'] | 27,571,245 | [['D27.720.013', 'J01.637.016'], ['B01.050'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G01.750.250.650.665', 'G01.750.770.578.665'], ['E01.370.350.800', 'E05.933.500'], ['E07.900']] | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Tracheal Atresia with Segmental Esophageal Duplication: An Unusual Anatomic Arrangement. | An unusual anatomic configuration of segmental tracheal agenesis/atresia with esophageal duplication on autopsy in a fetus that demised in utero at 29 weeks is reported. The mother was scanned initially for a cardiac anomaly at 20 weeks and on follow-up scan at 27 weeks had polyhydramnios and underwent amnioreduction. ... | ['Abnormalities, Multiple', 'Adult', 'Anal Canal', 'Autopsy', 'Biopsy', 'Constriction, Pathologic', 'Esophagus', 'Female', 'Fetal Death', 'Genetic Predisposition to Disease', 'Gestational Age', 'Heart Defects, Congenital', 'Humans', 'Kidney', 'Limb Deformities, Congenital', 'Phenotype', 'Predictive Value of Tests', 'Sp... | 26,367,770 | [['C16.131.077'], ['M01.060.116'], ['A03.556.124.526.070', 'A03.556.249.249.070'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['C23.300.287'], ['A03.556.875.500'], ['C13... | ['Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Lunar synchronization of in vitro steroidogenesis in ovaries of the golden rabbitfish, Siganus guttatus (Bloch). | To assess the relationship between lunar cycle and steroidogenesis in the ovaries of the golden rabbitfish, Siganus guttatus, the intact follicles of oocytes were incubated in vitro with human chorionic gonadotropin (hCG) and seven steroid hormones, 17alpha,20beta-dihydroxy-4-pregnen-3-one (DHP), 17alpha,20beta,21-trih... | ['17-alpha-Hydroxypregnenolone', 'Animals', 'Chorionic Gonadotropin', 'Culture Media', 'Estradiol', 'Female', 'In Vitro Techniques', 'Moon', 'Oocytes', 'Ovary', 'Perciformes', 'Steroids'] | 11,825,028 | [['D04.210.500.745.745.725.395', 'D06.472.040.585.745.500', 'D06.472.334.851.687.500.500'], ['B01.050'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['D27.720.470.305', 'E07.206'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['E05.481'], ['G01.060.075.730.700.20... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Real time NMR monitoring of local unfolding of HIV-1 protease tethered dimer driven by autolysis. | Structural studies in proteases have been hampered because of their inherent autolytic function. However, since autolysis is known to be mediated via protein unfolding, careful monitoring of the autolytic reaction has the potential to throw light on the folding-unfolding equilibria. In this paper we describe real time ... | ['Dimerization', 'Electrophoresis, Polyacrylamide Gel', 'Enzyme Stability', 'HIV Protease', 'Hydrolysis', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Models, Molecular', 'Protein Conformation', 'Protein Folding', 'Temperature'] | 11,376,663 | [['G02.206', 'G03.230'], ['E05.196.401.402', 'E05.301.300.319'], ['E05.916.360', 'G02.111.700.500'], ['D08.811.277.656.074.500.340', 'D08.811.277.656.300.048.340', 'D08.811.277.656.979.500', 'D12.776.964.775.375.545.750', 'D12.776.964.900.500.625'], ['G02.380'], ['G01.374.661', 'G02.111.490'], ['E05.196.867.519'], ['E0... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Lipoprotein particle concentrations in children and adults following Kawasaki disease. | OBJECTIVE: To test the hypothesis that children and adults with a history of Kawasaki disease (KD) are more likely to have abnormal lipoprotein particle profiles that could place them at increased risk for developing atherosclerosis later in life.STUDY DESIGN: Fasting serum samples were obtained from 192 children and 6... | ['Adolescent', 'Adult', 'Atherosclerosis', 'Body Mass Index', 'Case-Control Studies', 'Child', 'Child, Preschool', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Chylomicrons', 'Female', 'Follow-Up Studies', 'Humans', 'Lipoproteins', 'Magnetic Resonance Spectroscopy', 'Male', 'Mucocutaneous Lymph Node Syndrome', 'Risk Factor... | 25,039,043 | [['M01.060.057'], ['M01.060.116'], ['C14.907.137.126.307'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.060.406'], ['M01.060.406.448'], ['D04.210.500.247.808.197.238', 'D10.532.432.400'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Secretory antibody responses in axenic mice to perorally administered Staphylococcus aureus. | Topical oral immunization of axenic mice with non-replicating Staphylococcus aureus resulted in the production of both serum and salivary agglutinins. A latent period of approximately 5 days was noted before salivary antibodies were detected against both a carbohydrate (ChoA) and a protein (PrA) antigen isolated from t... | ['Agglutinins', 'Animals', 'Antibodies, Bacterial', 'Antibody Specificity', 'Antigens, Bacterial', 'Germ-Free Life', 'Immunoglobulin A', 'Immunoglobulin M', 'Kinetics', 'Mice', 'Saliva', 'Staphylococcal Infections'] | 640,714 | [['D27.505.696.477.136', 'D27.505.954.502.270.232'], ['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['G12.100'], ['D23.050.161'], ['G06.320'], ['D12.776.124.486.485.114.619.026', 'D12.776.124.790.651.114.619.026', 'D12.776.377.715.548.114.619.026'], ['D12.776... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of fibroblast growth factor receptor 2 in kidney mesenchyme. | Conditional deletion of murine fibroblast growth factor receptors (Fgfrs) 1 and 2 in metanephric mesenchyme leads to renal agenesis with unbranched ureteric buds; however, there are occasionally two buds per nephric duct. Our goal was to determine whether conditional deletion of Fgfr1 or Fgfr2 alone resulted in multipl... | ['Adaptor Proteins, Signal Transducing', 'Animals', 'Bone Morphogenetic Protein 4', 'Glial Cell Line-Derived Neurotrophic Factor', 'Humans', 'Kidney', 'Membrane Proteins', 'Mesoderm', 'Mice', 'Mice, Knockout', 'Phenotype', 'Phosphoproteins', 'Receptor, Fibroblast Growth Factor, Type 1', 'Receptor, Fibroblast Growth Fac... | 18,670,373 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['B01.050'], ['D12.644.276.954.200.400', 'D12.776.467.942.200.400', 'D23.529.942.200.400'], ['D12.644.276.860.381.500', 'D12.776.467.860.381.500', 'D12.776.631.600.381.500', 'D23.529.850.381.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Unusual skull base metastasis from neuroendocrine tumor: a case report. | BACKGROUND: With increasing treatment options available, neuroendocrine tumor has become a chronic disease and may present later on with atypical manifestation of disease spread once resistant to treatment.CASE PRESENTATION: A 74-year-old white British woman undergoing treatment for metastatic well-differentiated neuro... | ['Aged', 'Blepharoptosis', 'Fatal Outcome', 'Female', 'Headache', 'Humans', 'Intestinal Neoplasms', 'Liver Neoplasms', 'Magnetic Resonance Imaging', 'Neuroendocrine Tumors', 'Oculomotor Nerve Diseases', 'Positron-Emission Tomography', 'Skull Base Neoplasms'] | 31,466,520 | [['M01.060.116.100'], ['C11.338.204'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.476.411', 'C06.301.371.411', 'C06.405.249.411', 'C06.405.469.491'], ['C04.588.2... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Arsenic trioxide-induced apoptosis is independent of stress-responsive signaling pathways but sensitive to inhibition of inducible nitric oxide synthase in HepG2 cells. | Arsenic trioxide (As(2)O(3)) has been found to be remarkably effective in the treatment of patients with acute promyelocytic leukemia (APL). Although evidences for the proapoptotic activity of As(2)O(3) have been suggested in leukemic and other solid cancer cells, the nature of intracellular mechanisms is far from clea... | ['Antioxidants', 'Apoptosis', 'Arsenic Trioxide', 'Arsenicals', 'Cell Line, Tumor', 'Dose-Response Relationship, Drug', 'Enzyme Activation', 'Enzyme Inhibitors', 'Humans', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type II', 'Oxidative Stress', 'Oxides', 'Signal Transduction'] | 12,754,411 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G04.146.954.035'], ['D01.075.038', 'D01.650.550.125'], ['D01.075', 'D02.129'], ['A11.251.210.190', 'A11.251.860.180'], ['G07.690.773.875', 'G07.690.936.500'], ['G02.111.263', 'G03.328'], ['D27.505.519.389'], ['B01.050.150.900.649.313.988.400.112.400.400'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Acute interstitial nephritis during treatment with penicillin and cephalothin. | A case of non-oliguric acute interstitial nephritis during treatment with ampicillin, benzylpenicillin and cephalothin is reported. There were symptoms of drug hypersensitivity, including fever, exanthema, eosinophilia and elevated serum IgE. Renal biopsy showed marked interstitial edema and infiltration with numerous ... | ['Acute Disease', 'Adolescent', 'Ampicillin', 'Cephalothin', 'Drug Hypersensitivity', 'Humans', 'Immunoglobulins', 'Kidney', 'Male', 'Nephritis, Interstitial', 'Penicillin G'] | 636,917 | [['C23.550.291.125'], ['M01.060.057'], ['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['D02.065.589.099.249.190.210', 'D02.886.665.074.190.210', 'D03.633.100.300.249.190.210'], ['C20.543.206', 'C25.100.468'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Virtual World Currency Value Fluctuation Prediction System Based on User Sentiment Analysis. | In this paper, we present a method for predicting the value of virtual currencies used in virtual gaming environments that support multiple users, such as massively multiplayer online role-playing games (MMORPGs). Predicting virtual currency values in a virtual gaming environment has rarely been explored; it is difficu... | ['Attitude', 'Commerce', 'Economics', 'Emotions', 'Games, Recreational', 'Humans', 'Machine Learning', 'Models, Econometric', 'Social Support', 'Surveys and Questionnaires'] | 26,241,496 | [['F01.100'], ['J01.219'], ['I01.261', 'N03.219'], ['F01.470'], ['I03.450.642.693.465'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G17.035.250.500', 'L01.224.050.375.530'], ['E05.318.740.500.600.500', 'E05.599.835.890.500', 'N05.715.360.750.530.500.500', 'N06.850.520.830.500.600.500'], ['I01.880.853.500.600'],... | ['Psychiatry and Psychology [F]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 |
High-risk mild head injury. | The generally accepted definition of mild head injury includes Glasgow Coma Scale (GCS) scores of 13 to 15. However, many studies have shown that there is a heterogeneous pathophysiology among patients with GCS scores in this range. The current definition of mild head injury is misleading because patients classified in... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Craniocerebral Trauma', 'Female', 'Humans', 'Male', 'Middle Aged', 'Prognosis', 'Radiography', 'Risk Factors', 'Skull'] | 9,254,086 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['C10.900.300', 'C26.915.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789'], ['E01.370.350.700'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Waiting cycle times and generalized Haldane equality in the steady-state cycle kinetics of single enzymes. | Enzyme kinetics are cyclic. A more realistic reversible three-step mechanism of the Michaelis-Menten kinetics is investigated in detail, and three kinds of waiting cycle times T, T+, T- are defined. It is shown that the mean waiting cycle times T, T+, and T- are the reciprocal of the steady-state cycle flux Jss, the fo... | ['Enzymes', 'Kinetics', 'Probability', 'Time Factors'] | 18,069,809 | [['D08.811'], ['G01.374.661', 'G02.111.490'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
An in situ hybridization technique for the study of B19 human parvovirus replication in bone marrow cell cultures. | An in situ hybridization technique using digoxigenin labelling was developed to study B19 infection. By using appropriate DNA probes, transcription of structural and non-structural genes was detected in bone marrow cell cultures. Such a simple system is useful to the study of B19-cell interactions in non-permissive cel... | ['Base Sequence', 'Bone Marrow', 'Cells, Cultured', 'DNA Probes', 'Digoxigenin', 'Fluorescent Antibody Technique', 'Genes, Viral', 'Genome, Viral', 'Humans', 'In Situ Hybridization', 'Leukocytes, Mononuclear', 'Molecular Sequence Data', 'Parvovirus B19, Human', 'Transcription, Genetic', 'Virus Replication'] | 8,263,124 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A15.382.216'], ['A11.251'], ['D13.444.600.223', 'D27.505.259.750.600.223', 'D27.720.470.530.600.223'], ['D04.210.500.155.580.130.688.350'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
A remarkable inversion of structure-activity dependence on imido N-substituents with varying co-ligand topology and the synthesis of a new borate-free zwitterionic polymerisation catalyst. | Ethylene polymerisation productivities of tris(pyrazolyl)methane-supported catalysts [Ti(NR){HC(Me2pz)3}Cl2] show a dramatically different dependence on the imido R-group compared to those of their TACN analogues, attributed to differences in fac-N3 donor topology; when treated with AliBu3, the zwitterionic tris(pyrazo... | ['Aza Compounds', 'Borates', 'Catalysis', 'Imides', 'Ligands', 'Molecular Structure', 'Organometallic Compounds', 'Polymers', 'Pyrazoles', 'Titanium'] | 16,493,828 | [['D02.145'], ['D01.132.250.075', 'D01.248.497.158.076', 'D02.203.130.075'], ['G02.130'], ['D02.478'], ['D27.720.470.480'], ['G02.111.570', 'G02.466'], ['D02.691'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['D03.383.129.539'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Vacuum Infiltration-Centrifugation Method for Apoplastic Protein Extraction in Grapevine. | The apoplastic fluid moving in the extracellular space external to the plasma membrane provides a means of delivering molecules and facilitates intercellular communications. However, the apoplastic fluid extraction from in planta systems remains challenging and this is particularly true for grapevine (Vitis vinifera L.... | ['Blotting, Western', 'Centrifugation', 'Filtration', 'Intracellular Space', 'Plant Proteins', 'Proteome', 'Vacuum', 'Vitis'] | 27,665,564 | [['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.181'], ['E05.196.454', 'G01.280', 'G02.263'], ['A10.082.750', 'A11.284.430'], ['D12.776.765'], ['D12.776.817'], ['G01.374.715.902', 'G16.500.750.274.902', 'N06.230.300.100.185.902'], ['B01.650.940.800.575.912.250... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Adaptation to physical exertion at early stages of hypertension]. | A total of 230 patients with essential hypertension without signs of circulatory insufficiency were subjected to ventilation and pulmonary gas exchange studies under dosaged physical exercises, and 140 patients were reexamined following a therapeutic course. Disturbances in the patients' adaptation to physical exercise... | ['Adaptation, Physiological', 'Adolescent', 'Adult', 'Female', 'Humans', 'Hypertension', 'Lung', 'Male', 'Middle Aged', 'Oxygen Consumption', 'Physical Exertion'] | 1,011,524 | [['G07.025', 'G16.012.500'], ['M01.060.057'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['A04.411'], ['M01.060.116.630'], ['G03.680'], ['G11.427.683']] | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Inhibition of long-term potentiation in developing rat visual cortex but not hippocampus by in utero exposure to polychlorinated biphenyls. | The neurotoxic potential of polychlorinated biphenyls (PCBs) depends on the structure of the congener as well as on the age of the exposure. We exposed rats prenatally to a coplanar congener (PCB-77) or to a non-coplanar congener (PCB-47) and measured the amount of long-term potentiation (LTP) at postnatal days 11-19 i... | ['Aging', 'Animals', 'Electric Stimulation', 'Female', 'Hippocampus', 'Long-Term Potentiation', 'Polychlorinated Biphenyls', 'Pregnancy', 'Prenatal Exposure Delayed Effects', 'Rats', 'Rats, Long-Evans', 'Visual Cortex'] | 9,748,615 | [['G07.345.124'], ['B01.050'], ['E05.723.402'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['G11.561.638.350'], ['D02.309.750', 'D02.455.426.559.389.185.698', 'D02.455.526.439.773'], ['G08.686.784.769'], ['C13.703.824.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Metabolic responses of the rooster after exogenous thyroid hormones. | Total sensible heat loss, O2 consumption, and CO2 production were monitored in 20 White Leghorn roosters (1.85 +/- .05 kg body weight) subjected to either saline, or triiodothyronine (20 micrograms/kg; T3), or thyroxine (50 micrograms/kg; T4) administered in a single dose. Treatment occurred after a 26-hr fast and the ... | ['Animals', 'Body Temperature Regulation', 'Carbon Dioxide', 'Chickens', 'Male', 'Oxygen Consumption', 'Thyroxine', 'Triiodothyronine'] | 6,813,837 | [['B01.050'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['D01.200.200', 'D01.362.150', 'D01.650.550.200'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['G03.680'], ['D06.472.931.812', 'D12.125.072.050.767'], ['D06.472.931.740.385', 'D12.125.072.050.767.741.894']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Psychometric properties of the Spanish version of the diagnostic interview for depressive personality. | The aim of this study was to evaluate the reliability and validity of the Spanish-language version of the diagnostic interview for depressive personality (DIDP). The DIDP was administered to 328 consecutive outpatients and the test-retest and inter-rater reliability were assessed. Factor analysis was used in search of ... | ['Adult', 'Aged', 'Borderline Personality Disorder', 'Depressive Disorder', 'Diagnosis, Differential', 'Female', 'Humans', 'Interview, Psychological', 'Male', 'Middle Aged', 'Personality', 'Personality Disorders', 'Psychiatric Status Rating Scales', 'Psychometrics', 'Spain', 'Young Adult'] | 21,296,561 | [['M01.060.116'], ['M01.060.116.100'], ['F03.675.100'], ['F03.600.300'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.669.599'], ['M01.060.116.630'], ['F01.752'], ['F03.675'], ['F04.711.513.653'], ['F04.711.780'], ['Z01.542.846'], ['M01.060.116.815']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
[Surgical treatment of chronic anal fissures. Modification of the operation of Gabriel (author's transl)]. | The author reports a personal technique for treating chronic complicated anal fissures. The advantages of this technique are: 1. Complete removal of lesions (fissure and its sclerotic base). 2. Covering of the week area with good quality mucosa. 3. Small uncovered residual area with consequent fast healing. 4. Nonethel... | ['Chronic Disease', 'Fissure in Ano', 'Hemorrhoids', 'Humans', 'Methods'] | 1,199,649 | [['C23.550.291.500'], ['C06.405.469.860.101.430'], ['C06.405.469.860.401', 'C14.907.449'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581']] | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Iatrogenic cerebral abscess leading to resolution of severe delusional disorder. | A cerebral abscess (focal infection of brain parenchyma) carries a high mortality and morbidity. Iatrogenic cerebral abscesses are less common and make up 10% of all cases. The presence of a cerebral abscess can rarely improve a patient's prognosis and quality of life, however this case illustrates an abscess and its t... | ['Administration, Oral', 'Adult', 'Anti-Bacterial Agents', 'Brain Abscess', 'Female', 'Humans', 'Iatrogenic Disease', 'Magnetic Resonance Imaging', 'Meropenem', 'Neurophysiological Monitoring', 'Remission Induction', 'Schizophrenia, Paranoid'] | 31,796,437 | [['E02.319.267.100'], ['M01.060.116'], ['D27.505.954.122.085'], ['C01.207.090', 'C01.830.025.160', 'C10.228.140.116', 'C10.228.228.090'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.291.875'], ['E01.370.350.825.500'], ['D02.065.589.099.124.300.750', 'D03.633.100.300.124.300.750'], ['E01.370.520.596'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Urbanization and the risk for chronic diseases of lifestyle in the black population of the Cape Peninsula, South Africa. | BACKGROUND: Men and women have experienced differing patterns of urbanization. Men spent more time in the city as migrant labourers, which could be attributed to the influx control legislation during the apartheid years.OBJECTIVE: To investigate urban exposure among black people of the Cape Peninsula, South Africa, in ... | ['Adolescent', 'Adult', 'African Americans', 'African Continental Ancestry Group', 'Chronic Disease', 'Female', 'Health Behavior', 'Humans', 'Life Style', 'Male', 'Middle Aged', 'Risk Factors', 'South Africa', 'Urban Population'] | 9,304,495 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.686.508.100'], ['C23.550.291.500'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.458'], ['M01.060.116.630'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Hyperglycemia during chemotherapy for hematologic and solid tumors is correlated with increased toxicity. | BACKGROUND: Few data are available concerning how glycemic control can affect outcomes in cancer patients treated with chemotherapy.METHODS: Charts of non-Hodgkin lymphoma (NHL) and prostate cancer (PC) patients treated at Moffitt Cancer Center between January 1999 and September 2006 were reviewed, and patients who rec... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antibodies, Monoclonal, Murine-Derived', 'Antineoplastic Combined Chemotherapy Protocols', 'Blood Glucose', 'Cyclophosphamide', 'Docetaxel', 'Doxorubicin', 'Female', 'Florida', 'Humans', 'Hyperglycemia', 'Kaplan-Meier Estimate', 'Linear Models', 'Lymphoma, Non-Hodgkin', 'Male', '... | 20,622,641 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.124.486.485.114.224.075', 'D12.776.124.790.651.114.224.075', 'D12.776.377.715.548.114.224.284'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D09.947.875.359.448.500'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D02... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Monoamine systems in the discriminative effects of spiradoline, a kappa-opioid agonist. | The results of studies on mice indicate that the antinociceptive effects of kappa-opioid agonists are due, in part, to activation of the 5-HT2 type of serotonin receptor. One objective of this study was to determine if the discriminative effects of spiradoline, a kappa-opioid agonist, are mediated by 5-HT2 receptors in... | ['Analgesics', 'Animals', 'Avoidance Learning', 'Biogenic Monoamines', 'Discrimination, Psychological', 'Dopamine Antagonists', 'Fenfluramine', 'Fluoxetine', 'Generalization, Stimulus', 'Ketanserin', 'Male', 'Piperidines', 'Pyrrolidines', 'Rats', 'Rats, Sprague-Dawley', 'Receptors, Opioid, kappa', 'Serotonin', 'Seroton... | 8,208,776 | [['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['F02.463.425.097', 'F02.463.785.373.173'], ['D02.092.211.215'], ['F02.463.593.257'], ['D27.505.519.625.150.175', 'D27.505.696.577.150.175'], ['D02.092.471.683.467'], ['D02.092.831.280'], ['F02.463.425.357.526'], ['D03.383.621.365', 'D03.633.100.786.830.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Interferon-ã decreases chondroitin sulfate proteoglycan expression and enhances hindlimb function after spinal cord injury in mice. | Glial cells, including astrocytes and macrophages/microglia, are thought to modulate pathological states following spinal cord injury (SCI). In the present study, we evaluated the therapeutic effects of interferon-ã (IFN-ã), which is one of the cytokines regulating glial function, in a mouse contusive SCI model. We fou... | ['Analysis of Variance', 'Animals', 'Astrocytes', 'Blotting, Western', 'Cells, Cultured', 'Chondroitin Sulfate Proteoglycans', 'Disease Models, Animal', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Glial Cell Line-Derived Neurotrophic Factor', 'Hindlimb', 'Immunohistochemistry', 'Interferon-gamma', 'Mice', 'Microgli... | 20,925,481 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['A08.637.200', 'A11.650.200'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251'], ['D09.698.735.200', 'D12.776.395.650.750'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Racial/Ethnic Differences in 25-Hydroxy Vitamin D and Parathyroid Hormone Levels and Cardiovascular Disease Risk Among Postmenopausal Women. | Background Recent evidence suggests that racial/ethnic differences in circulating levels of free or bioavailable 25-hydroxy vitamin D (25[ OH ]D) rather than total 25( OH )D may explain apparent racial disparities in cardiovascular disease ( CVD ). We prospectively examined black-white differences in the associations o... | ['Aged', 'Biomarkers', 'Cardiovascular Diseases', 'Case-Control Studies', 'Continental Population Groups', 'Ethnic Groups', 'Female', 'Follow-Up Studies', 'Forecasting', 'Humans', 'Incidence', 'Middle Aged', 'Parathyroid Hormone', 'Postmenopause', 'Prospective Studies', 'Risk Assessment', 'Risk Factors', 'United States... | 30,764,690 | [['M01.060.116.100'], ['D23.101'], ['C14'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['M01.686.508'], ['M01.686.754', 'N01.224.317'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['I01.320'], ['B01.050.150.900.649.313.988.400.112.400.40... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Surveillance of avian influenza virus in wild bird fecal samples from South Korea, 2003-2008. | We analyzed the results from nationwide surveillance of avian influenza (AI) from birds in South Korea's major wild bird habitats and the demilitarized zone of South Korea, 2003-2008. Of 28,214 fecal samples analyzed, 225 yielded influenza viruses, for a prevalence of 0.8%. Hemagglutinin (HA) subtypes H1-H12 and all ni... | ['Animals', 'Animals, Wild', 'Anseriformes', 'Birds', 'Feces', 'Female', 'Influenza A virus', 'Influenza in Birds', 'Male', 'Prevalence', 'Republic of Korea', 'Sentinel Surveillance', 'Serotyping', 'Species Specificity'] | 20,688,693 | [['B01.050'], ['B01.050.050.300'], ['B01.050.150.900.248.050'], ['B01.050.150.900.248'], ['A12.459'], ['B04.820.480.968.405.400'], ['C01.925.782.620.300', 'C22.131.450'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['Z01.252.474.557.750'], ['E05.318.... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
The fate of the adult exstrophy patient. | Between 1968 and 1993, 101 patients with bladder exstrophy or incontinent epispadias underwent surgery at our hospital. The standard procedure was ureterosigmoidostomy and additional genital reconstruction. Of the 56 patients who have reached adulthood 45 could be interviewed regarding social integration, sexuality and... | ['Adolescent', 'Adult', 'Bladder Exstrophy', 'Female', 'Genitalia, Female', 'Genitalia, Male', 'Humans', 'Infertility, Male', 'Male', 'Postoperative Complications', 'Treatment Outcome', 'Urinary Diversion'] | 7,933,172 | [['M01.060.057'], ['M01.060.116'], ['C12.706.132', 'C12.777.829.132', 'C13.351.875.132', 'C13.351.968.829.132', 'C16.131.939.132'], ['A05.360.319'], ['A05.360.444'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.365.700'], ['C23.550.767'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Modeling and fixed bed column adsorption of As(V) on laterite soil. | Laterite soil, an abundant locally available natural adsorbent, has been evaluated for As(V) removal from aqueous solutions in column mode operation. The column studies were conducted using columns of 10, 20, 30 cm bed depth with 2 cm internal diameter. Initial As(V) concentration was 0.5 mg/L and flow rate was 7.75 mL... | ['Adsorption', 'Arsenic', 'Models, Chemical', 'Soil', 'Water Pollutants, Chemical', 'Water Purification'] | 17,849,300 | [['G01.030', 'G02.020'], ['D01.268.513.249'], ['E05.599.495'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['D27.888.284.903.655'], ['N06.850.780.200.800.800.900.900', 'N06.850.860.510.900.900']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Herbal diterpenoids induce growth arrest and apoptosis in colon cancer cells with increased expression of the nonsteroidal anti-inflammatory drug-activated gene. | Novel chemotherapeutic agents derived from active phytochemicals could be used as adjuvants and improve the anti-carcinogenicity of standard drug treatments. However, their precise mechanisms of action are sometimes unclear. In this study, the anti-carcinogenic effect of the herbal diterpenoid pseudolaric acid B (PAB) ... | ['Antineoplastic Agents, Phytogenic', 'Apoptosis', 'Cell Cycle', 'Cell Line, Tumor', 'Cell Nucleus', 'Cell Proliferation', 'Colonic Neoplasms', 'Cyclooxygenase 2', 'Cytokines', 'DNA Fragmentation', 'Diterpenes', 'Epoxy Compounds', 'Flow Cytometry', 'Fluorescent Dyes', 'Gene Expression Regulation, Neoplastic', 'Growth D... | 17,258,704 | [['D27.505.954.248.179'], ['G04.146.954.035'], ['G04.144'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G04.161.750', 'G07.345.249.410.750'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.49... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
neo-Clerodane Diterpenoids and Other Constituents of Salvia filipes. | A series of neo-clerodane-type diterpenoids were isolated from the aerial parts of Salvia filipes, including the new compounds 4-epi-polystachyne A (1), salvifilines A (3), C (7), and D (8), and salvifiline B, which was isolated as the 15-O-methyl derivatives 4/5. In addition, the five known diterpenoids (2, 9-12), tog... | ['Diterpenes, Clerodane', 'Drug Screening Assays, Antitumor', 'Humans', 'Mexico', 'Molecular Structure', 'Nuclear Magnetic Resonance, Biomolecular', 'Pentacyclic Triterpenes', 'Plant Components, Aerial', 'Salvia', 'Triterpenes'] | 27,679,866 | [['D02.455.849.291.228'], ['E01.370.225.500.388', 'E05.200.500.388', 'E05.242.417', 'E05.337.550.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.589'], ['G02.111.570', 'G02.466'], ['E05.196.867.519.550'], ['D02.455.849.919.530'], ['A18.024'], ['B01.650.940.800.575.912.250.583.520.922'], ['D02.455.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Evaluation of a patient-specific cost function to predict the influence of foot path on the knee adduction torque during gait. | A large external knee adduction torque during gait has been correlated with the progression of knee osteoarthritis (OA). Though foot path changes (e.g. toeing out) can reduce the adduction torque, no method currently exists to predict whether an optimal foot path exists for a specific patient. This study evaluates a pa... | ['Adult', 'Biomechanical Phenomena', 'Biomedical Engineering', 'Computer Simulation', 'Gait', 'Humans', 'Knee Joint', 'Male', 'Models, Biological', 'Osteoarthritis', 'Torque'] | 17,943,485 | [['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['H02.070', 'J01.293.140'], ['L01.224.160'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.583.475'], ['E05.599.395'], ['C05.550.114.606', 'C05.799.613'], ['G01.374.860.500']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 |
Nursing faculty collaboration viewed through feminist process. Charleston Faculty Practice Conference Group. | The process of evolution experienced by a faculty practice group is viewed through feminist process. A decision to write an article describing their model focused group efforts and served as a catalyst for clarifying needs, values, expectations, and feelings about the group and group process. The group, which began as ... | ['Authorship', 'Faculty, Nursing', 'Female', 'Goals', 'Group Processes', 'Group Structure', 'Humans', 'Leadership', 'Nurses', 'Social Support', "Women's Rights", 'Writing'] | 3,079,984 | [['L01.559.423.906.215'], ['M01.526.485.390', 'M01.526.702.250.473', 'N02.360.390'], ['F01.658.500'], ['F01.829.316'], ['F01.829.316.274'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.609'], ['M01.526.485.650', 'N02.360.650'], ['I01.880.853.500.600'], ['I01.880.604.473.850', 'N03.706.437.850'], ['L01.559... | ['Information Science [L]', 'Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
The structure of the specific capsular polysaccharide of Rhodococcus equi serotype 4. | The specific capsular polysaccharide produced by Rhodococcus equi serotype 4 was found to be a high-molecular-weight acidic polymer composed of D-glucose, D-mannose, pyruvic acid and a previously unidentified 5-amino-3,5-dideoxynonulosonic (rhodaminic) acid in the proportions 2:1:1:1. Structural analysis, employing a c... | ['Animals', 'Carbohydrate Conformation', 'Carbohydrate Sequence', 'Magnetic Resonance Spectroscopy', 'Molecular Sequence Data', 'Polysaccharides', 'Polysaccharides, Bacterial', 'Rhodococcus equi', 'Serotyping', 'Spectrometry, Mass, Fast Atom Bombardment'] | 10,573,859 | [['B01.050'], ['G02.111.570.820.235'], ['G02.111.570.160', 'L01.453.245.667.160'], ['E05.196.867.519'], ['L01.453.245.667'], ['D09.698'], ['D09.698.718', 'D23.050.161.616'], ['B03.510.024.981.775.700'], ['E01.370.225.812.742', 'E01.370.225.875.150.125.890', 'E05.200.812.742', 'E05.200.875.150.125.890', 'E05.478.594.780... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Lattice Strain Defects in a Ceria Nanolayer. | An ultrathin two-dimensional CeO2 (ceria) phase on a Cu(110) surface has been fabricated and fully characterized by high-resolution scanning tunneling microscopy, photoelectron spectroscopy, and density functional theory. The atomic lattice structure of the ceria/Cu(110) system is revealed as a hexagonal CeO2(111)-type... | ['Adsorption', 'Cerium', 'Copper', 'Models, Molecular', 'Oxidation-Reduction', 'Photoelectron Spectroscopy', 'Surface Properties', 'Thermodynamics'] | 26,988,695 | [['G01.030', 'G02.020'], ['D01.268.558.362.249', 'D01.552.550.399.249'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['E05.599.595'], ['G02.700', 'G03.295.531'], ['E05.196.867.618'], ['G02.860'], ['G01.906']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Affective disorders and ABO blood groups: new data and a reanalysis of the literature using the logistic transformation of proportions. | No statistically significant associations were found between ABO blood group distributions and RDC subtype diagnoses in 79 subjects with unipolar (single episode and recurrent) and bipolar major depressive disorder using data from our sample. We discuss methodological issues related to the control samples and choice of... | ['ABO Blood-Group System', 'Bipolar Disorder', 'Depressive Disorder', 'Female', 'Humans', 'Male', 'Research Design', 'Statistics as Topic'] | 6,747,910 | [['D23.050.301.290.031', 'D23.050.705.230.031'], ['F03.084.500'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581.500', 'H01.770.644.728'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830']] | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Isolation and differential expression of a novel MAP kinase gene DoMPK4 in Dendrobium officinale. | Mitogen-activated protein kinases (MAPKs) are important signaling transduction components well conserved in eukaryotes and play essential roles in various physiological, developmental and hormonal responses in plant. In the present study, a MAPK gene, designated as DoMPK4 (GenBank accession No. JX297597), is identified... | ['Amino Acid Sequence', 'DNA, Complementary', 'DNA, Plant', 'Dendrobium', 'Gene Expression Regulation, Plant', 'Mitogen-Activated Protein Kinases', 'Phylogeny', 'Plant Leaves', 'Plant Proteins', 'Plant Roots', 'Plant Stems', 'Seeds', 'Sequence Alignment'] | 25,233,643 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['D13.444.308.435'], ['B01.650.940.800.575.912.250.618.100.640.222'], ['G05.308.375'], ['D08.811.913.696.620.682.700.567', 'D12.644.360.450', 'D12.776.476.450'], ['G05.697', 'G16.075.605', 'L01.10... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Expression of recombinant human nerve growth factor beta in milk of goats by recombinant replication-defective adenovirus. | For producing a large quantity of human nerve growth factor beta (hNGF-beta), the recombinant adenovirus containing an expression cassette of hNGF-beta complementary DNA gene was constructed and then instilled directly into goats' mammary glands. The recombinant hNGF-beta was detected in the milk. The maximal expressio... | ['Adenoviridae', 'Animals', 'Cell Line', 'Genetic Vectors', 'Goats', 'Humans', 'Mammary Glands, Animal', 'Milk', 'Nerve Growth Factor', 'Recombinant Proteins', 'Virus Replication'] | 18,754,080 | [['B04.280.030'], ['B01.050'], ['A11.251.210'], ['G05.360.337'], ['B01.050.150.900.649.313.500.380.513'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A10.336.482', 'A13.589'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525'], ['D12.644.276.860.437', 'D12.776.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Neuropsychological impairments in anorexia nervosa: a spanish sample pilot study. | This work was aimed at obtaining a profile of neuropsychological impairments in young Spanish participants with anorexia nervosa (AN) to demonstrate that right-hemisphere and frontal capacity impairments are present not only in the acute phase but also after weight recovery in a Spanish sample compared with a healthy c... | ['Adolescent', 'Adult', 'Anorexia Nervosa', 'Attention', 'Body Mass Index', 'Cognition Disorders', 'Female', 'Frontal Lobe', 'Humans', 'Inhibition, Psychological', 'Intelligence', 'Male', 'Memory, Short-Term', 'Neuropsychological Tests', 'Pilot Projects', 'Spain', 'Statistics as Topic', 'Young Adult'] | 25,084,841 | [['M01.060.057'], ['M01.060.116'], ['F03.400.125'], ['F02.830.104.214'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['F03.615.250'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.544', 'F02.463.425.475', 'F02.739.794.40... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation. | Site-specific recombinase-mediated genetic technology, such as inducible Cre-loxP recombination (CreER), is widely used for in vivo genetic manipulation with temporal control. The Cre-loxP technology improves our understanding on the in vivo function of specific genes in organ development, tissue regeneration, and dise... | ['Alleles', 'Animals', 'Cell Lineage', 'Female', 'Fibroblasts', 'Gene Deletion', 'Gene Expression', 'Integrases', 'Mice', 'Mice, Inbred C57BL', 'Mice, Transgenic', 'Recombination, Genetic'] | 31,943,281 | [['G05.360.340.024.340.030'], ['B01.050'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['A11.329.228'], ['G05.365.590.762.320', 'G05.558.800.320'], ['G05.297'], ['D08.811.739.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.31... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Examining the statistical properties of fine-scale mapping in large-scale association studies. | Interpretation of dense single nucleotide polymorphism (SNP) follow-up of genome-wide association or linkage scan signals can be facilitated by establishing expectation for the behaviour of primary mapping signals upon fine-mapping, under both null and alternative hypotheses. We examined the inferences that can be made... | ['Chromosome Mapping', 'Gene Frequency', 'Genetic Diseases, Inborn', 'Genetic Linkage', 'Genetic Markers', 'Genome, Human', 'Haplotypes', 'Humans', 'Linkage Disequilibrium', 'Polymorphism, Single Nucleotide', 'Probability'] | 18,064,636 | [['E05.393.183'], ['G05.330'], ['C16.320'], ['G05.348'], ['D23.101.387', 'G05.695.450'], ['G05.360.340.350'], ['G05.380.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.348.500'], ['G05.365.795.598'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A simplified guide for arranging 30 degrees Pilkington Turner posterior denture teeth in a balanced occlusion. | A simple technique is presented for achieving balanced occlusion when setting 30 degrees Pilkington-Turner teeth. This technique involves the rotation of the mandibular posterior teeth around three axes: the vertical axis, to align the grooves and embrasures with the lateral path of the movement of the cusps; the mesio... | ['Dental Occlusion, Balanced', 'Denture Design', 'Humans', 'Rotation', 'Surface Properties', 'Tooth Crown', 'Tooth, Artificial'] | 17,451,472 | [['E06.276.293'], ['E06.780.346.760.300', 'E06.912.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.482.703'], ['G02.860'], ['A14.549.167.900.710'], ['E06.780.346.875', 'E07.695.190.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cultivation of methanogens under low-hydrogen conditions by using the coculture method. | We previously reported the isolation of novel methanogens by using a new cultivation method, referred to as the coculture method. Here, we extended our coculture method to various anaerobic environmental samples. As a result, we successfully cultivated some uncharacterized methanogens in coculture enrichments and event... | ['Bacteria', 'Cluster Analysis', 'Coculture Techniques', 'DNA, Archaeal', 'DNA, Bacterial', 'DNA, Ribosomal', 'Environmental Microbiology', 'Hydrogen', 'Methane', 'Molecular Sequence Data', 'Phylogeny', 'RNA, Ribosomal, 16S', 'Sequence Analysis, DNA'] | 19,465,530 | [['B03'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['E05.481.500.374'], ['D13.444.308.180'], ['D13.444.308.212'], ['D13.444.308.475'], ['H01.158.273.540.274', 'N06.850.425'], ['D01.268.406', 'D01.362.340'], ['D02.455.326.146.571'], ['L01.453.245.667'], ['G05.697', 'G16.075.605', 'L01.100.697']... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Predictive value of plasma thrombomodulin in preeclampsia and gestational hypertension. | In a prospective longitudinal study, 130 primigravidae at risk for preeclampsia were examined and plasma sampling performed in 45 of them. Plasma thrombomodulin (pTM) was sequentially measured at weeks 12, 24 and 32 of gestation and after delivery in 20 primigravidae who developed either mild preeclampsia (n = 8) or ge... | ['Adult', 'Biomarkers', 'Creatinine', 'Female', 'Humans', 'Infant, Newborn', 'Kidney Function Tests', 'Pre-Eclampsia', 'Predictive Value of Tests', 'Pregnancy', 'Pregnancy Outcome', 'Pregnancy Trimesters', 'Prospective Studies', 'ROC Curve', 'Risk Factors', 'Thrombomodulin'] | 9,657,429 | [['M01.060.116'], ['D23.101'], ['D03.383.129.308.207'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E01.370.390.400'], ['C13.703.395.249'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['G08.686.784.769'], ['E01.789.700', 'G08.686.784.769.496'], ['G08.686.70... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Isolation and identification of the C6-hydroxy and C20-hydroxy metabolites and glucuronide conjugate of methylprednisolone by preparative high-performance liquid chromatography from urine of patients receiving high-dose pulse therapy. | In the present study metabolites of methylprednisolone were detected using gradient elution high-performance liquid chromatography. Separation was performed by a Cp Spherisorb ODS 5 microm (250 mmx4.6 mm I.D.) column, connected to a guard column, packed with pellicular reversed phase. The mobile phase was a mixture of ... | ['Chromatography, High Pressure Liquid', 'Humans', 'Methylprednisolone', 'Multiple Sclerosis', 'Spectrum Analysis'] | 10,348,182 | [['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.432.769.795.539'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['E05.196.867']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Resource utilization and costs for treatment of stroke patients in an acute stroke unit in Greece. | BACKGROUND: Stroke comprises the leading cause of death in Greece, and more than 40% of the overall lifetime cost for stroke care, represents the acute phase hospitalization. The aim of the present study was to assess the resource utilization and estimate the costs for treatment of stroke patients in an Acute Stroke Un... | ['Adult', 'Aged', 'Aged, 80 and over', 'Brain Ischemia', 'Female', 'Greece', 'Health Resources', 'Hospital Costs', 'Hospitalization', 'Humans', 'Male', 'Middle Aged', 'Stroke'] | 26,795,492 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.140.300.150', 'C14.907.253.092'], ['Z01.542.383'], ['N03.349.340', 'N05.300.420'], ['N03.219.151.400.687', 'N03.219.262.500', 'N05.300.375.500'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.6... | ['Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Anti-fibrotic effects via regulation of transcription factor Sp1 on hepatic stellate cells. | BACKGROUND: Hepatic stellate cells (HSCs), the central cells in hepatic fibrosis, are characterized by sustaining activation, a process that consists in increased proliferation and over-expression of fibrotic genes. Transcription factor Sp1 mediates the expression of a variety of fibrotic genes expression and thereby p... | ['Actins', 'Becaplermin', 'Cell Line', 'Collagen Type I', 'Cyclin D1', 'Cyclin-Dependent Kinase Inhibitor p27', 'Hepatic Stellate Cells', 'Humans', 'Oligodeoxyribonucleotides', 'Promoter Regions, Genetic', 'Proto-Oncogene Proteins c-sis', 'Sp1 Transcription Factor', 'Tissue Inhibitor of Metalloproteinase-1', 'Transfect... | 22,415,074 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D12.644.276.910.650.500', 'D12.776.260.690.500', 'D12.776.467.910.650.500', 'D23.529.910.650.500'], ['A11.251.210'], ['D05.750.078.280.300.100', 'D12.776.860.300.250.300.100'], ['D12.644.360.262.150.100', 'D12.776.167.218.150.100', 'D12.776.476.2... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Using fixed-node diffusion Monte Carlo to investigate the effects of rotation-vibration coupling in highly fluxional asymmetric top molecules: application to H2D+. | A fixed-node diffusion Monte Carlo approach for obtaining the energies and wave functions of the rotationally excited states of asymmetric top molecules that undergo large amplitude, zero-point vibrational motions is reported. The nodal surfaces required to introduce rotational excitation into the diffusion Monte Carlo... | ['Deuterium', 'Diffusion', 'Hydrogen', 'Monte Carlo Method', 'Rotation', 'Vibration'] | 23,343,266 | [['D01.268.406.500', 'D01.362.340.500', 'D01.496.289'], ['G01.202', 'G02.196'], ['D01.268.406', 'D01.362.340'], ['E05.318.740.525', 'L01.906.394.422', 'N05.715.360.750.540', 'N06.850.520.830.525'], ['G01.482.703'], ['G01.374.930']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Executive function relates to surface area of frontal and temporal cortex in very-low-birth-weight late teenagers. | BACKGROUND: Being born with very low birth weight (VLBW; birth weight (BW) ?1500 g) is associated with increased risk of maldevelopment of the immature brain which may affect neurological functioning. Deficits in attention and executive function problems have been reported in VLBW survivors compared with healthy subjec... | ['Adolescent', 'Adolescent Development', 'Attention', 'Case-Control Studies', 'Child Development', 'Executive Function', 'Female', 'Frontal Lobe', 'Humans', 'Infant, Newborn', 'Infant, Very Low Birth Weight', 'Male', 'Temporal Lobe', 'Young Adult'] | 26,939,083 | [['M01.060.057'], ['F01.525.049', 'G07.345.374.500'], ['F02.830.104.214'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['F01.525.200', 'G07.345.374.750'], ['F02.463.217'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['M01.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Wheat gliadin nanoparticle size control by determination of the solubility parameters of these plant proteins]. | Gliadins nanoparticles, protein complex from wheat gluten, were prepared by coacervation (macromolecules desolvatation). The objective was to prepare nanometric colloidal systems whith both smallest particle size and polidispersity index. Macromolecules solvent choice is predominant. Their total solvatation enables of ... | ['Gliadin', 'Particle Size', 'Solubility', 'Solvents', 'Triticum'] | 11,924,512 | [['D12.776.765.433.500.500.400', 'D12.776.765.725.500.500.400'], ['G02.712'], ['G02.805'], ['D27.720.844'], ['B01.650.940.800.575.912.250.822.918']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fabrication of UMCM-1 based monolithic and hollow fiber - Metal-organic framework deep eutectic solvents/molecularly imprinted polymers and their use in solid phase microextraction of phthalate esters in yogurt, water and edible oil by GC-FID. | In this study, for the first time, hollow fiber and monolithic fiber were fabricated based on metal-organic framework deep eutectic solvents/molecularly imprinted polymers (MOF- DES/MIPs) and were used for microextraction of phthalate esters under termed hollow fiber liquid membrane-protected solid-phase microextractio... | ['Adsorption', 'Chromatography, Gas', 'Esters', 'Limit of Detection', 'Metal-Organic Frameworks', 'Molecular Imprinting', 'Phthalic Acids', 'Polymers', 'Solid Phase Microextraction', 'Solvents', 'Soybean Oil', 'Water', 'Yogurt'] | 31,968,292 | [['G01.030', 'G02.020'], ['E05.196.181.349'], ['D02.241.400'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['D02.691.638', 'D05.750.215'], ['E05.196.655', 'E05.197.453', 'J01.897.836.249.437'], ['D02.241.223.805'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['E05.196.155.800.500'], ['... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
ASPH-notch Axis guided Exosomal delivery of Prometastatic Secretome renders breast Cancer multi-organ metastasis. | BACKGROUND: Aspartate â-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication. This st... | ['Animals', 'Biomarkers', 'Breast Neoplasms', 'Calcium-Binding Proteins', 'Cell Communication', 'Cell Line, Tumor', 'Cell Transformation, Neoplastic', 'Disease Models, Animal', 'Exosomes', 'Extracellular Matrix', 'Female', 'Genes, Reporter', 'Heterografts', 'Humans', 'Immunohistochemistry', 'Ligands', 'Matrix Metallopr... | 31,694,640 | [['B01.050'], ['D23.101'], ['C04.588.180', 'C17.800.090.500'], ['D12.776.157.125'], ['G04.085'], ['A11.251.210.190', 'A11.251.860.180'], ['C04.697.098.500', 'C23.550.727.098.500'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['A11.284.295.588.750', 'A11.284.430.214.190.875.190.880.495'], ['A11.284.295.310'], ['G05.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Healing with animals in the Levant from the 10th to the 18th century. | Animals and products derived from different organs of their bodies have constituted part of the inventory of medicinal substances used in various cultures since ancient times. The article reviews the history of healing with animals in the Levant (The Land of Israel and parts of present-day Syria, Lebanon, and Jordan, d... | ['Animals', 'Ethnopharmacology', 'History, 15th Century', 'History, 16th Century', 'History, 17th Century', 'History, 18th Century', 'History, Medieval', 'Humans', 'Materia Medica', 'Medicine, Traditional', 'Middle East', 'Pharmacognosy'] | 16,504,024 | [['B01.050'], ['H01.158.703.015', 'H02.628.100', 'I01.076.201.450.654.252'], ['K01.400.475.500'], ['K01.400.475.750'], ['K01.400.504.750'], ['K01.400.504.875'], ['K01.400.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D26.526'], ['E02.190.488', 'I01.076.201.450.654'], ['Z01.252.245.500'], ['H01.158.273.118.5... | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 |
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