Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Achieving irreducibility of the Markov chain Monte Carlo method applied to pedigree data. | Markov chain Monte Carlo (MCMC) methods have been explored by various researchers as an alternative to exact probability computation in statistical genetics. The objective is to simulate a Markov chain with the desired equilibrium distribution. If the transition kernel is aperiodic and irreducible, then convergence to ... | ['Algorithms', 'Alleles', 'Analysis of Variance', 'Biometry', 'Female', 'Genetics, Medical', 'Genotype', 'Humans', 'Likelihood Functions', 'Male', 'Markov Chains', 'Monte Carlo Method', 'Pedigree', 'Probability'] | 8,409,623 | [['G17.035', 'L01.224.050'], ['G05.360.340.024.340.030'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['E05.318.740.225', 'N06.850.505.200'], ['H01.158.273.343.385.500', 'H02.403.350'], ['G05.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Calcium control of the intestinal microvillus cytoskeleton: its implications for the regulation of microfilament organizations. | The microvillus core-filament bundle from intestinal epithelial cells is a highly ordered structure containing actin and four major associated proteins. Two of these, villin and calmodulin, bind calcium ions (Kd approximately 10(-6) M) in the physiologically important range. Because ethylene glycol bis(beta-aminoethyl ... | ['Actins', 'Animals', 'Calcium', 'Calcium-Binding Proteins', 'Calmodulin', 'Carrier Proteins', 'Cell Membrane', 'Chickens', 'Cytoskeleton', 'Membrane Glycoproteins', 'Membrane Proteins', 'Microfilament Proteins', 'Microvilli'] | 6,935,660 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.125'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['D12.776.157'], ['A11.284.149'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.2... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Late sequelae of coronary heart disease: incidence and angiocardiographic identification (author's transl)]. | Ventriculography was performed in 154 patients with angiographic evidence of coronary heart disease (high-grade stenosis or total occlusion). Functional disorders or morphologic changes were demonstrated in 81% of cases. However, vascular lesions were often found without evidence of ventricular dysfunction in patients ... | ['Adult', 'Age Factors', 'Aged', 'Angiocardiography', 'Coronary Disease', 'Female', 'Humans', 'Male', 'Middle Aged', 'Time Factors'] | 7,302,477 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E01.370.350.130.249', 'E01.370.350.700.060.050', 'E01.370.370.050.050', 'E01.370.370.380.050'], ['C14.280.647.250', 'C14.907.585.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G01.910.857']] | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Dynamic cardiac PET imaging: extraction of time-activity curves using ICA and a generalized Gaussian distribution model. | Kinetic modeling of metabolic and physiologic cardiac processes in small animals requires an input function (IF) and a tissue time-activity curves (TACs). In this paper, we present a mathematical method based on independent component analysis (ICA) to extract the IF and the myocardium's TACs directly from dynamic posit... | ['Algorithms', 'Animals', 'Diagnostic Techniques, Cardiovascular', 'Heart', 'Humans', 'Kinetics', 'Male', 'Normal Distribution', 'Positron-Emission Tomography', 'Rats', 'Rats, Inbred F344', 'Rubidium Radioisotopes', 'Signal Processing, Computer-Assisted', 'Time Factors'] | 23,060,316 | [['G17.035', 'L01.224.050'], ['B01.050'], ['E01.370.370'], ['A07.541'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.374.661', 'G02.111.490'], ['E05.318.740.994.500', 'G17.820.500', 'N05.715.360.750.750.565', 'N06.850.520.830.994.500'], ['E01.370.350.350.800.700', 'E01.370.350.600.350.800.399', 'E01.370.350.7... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Sequence and function analysis of a 4.3 kb fragment of Saccharomyces cerevisiae chromosome II including three open reading frames. | The nucleotide sequence of a fragment of 4337 base pairs of Saccharomyces cerevisiae chromosome II has been determined. The sequence contains three open reading frames, one of them being incomplete. Deletion analysis showed that YBR12.31 is essential for yeast growth, while deletion mutants of YBR12.32 and YBR12.33 are... | ['Amino Acid Sequence', 'Base Sequence', 'Chromosomes, Fungal', 'Codon', 'Fungal Proteins', 'Molecular Sequence Data', 'Mutagenesis, Insertional', 'Open Reading Frames', 'Phenotype', 'Repressor Proteins', 'Restriction Mapping', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Sequence Analysis, DNA', '... | 8,212,898 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.187.360', 'A19.311', 'G05.360.162.360'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['D12.776.354'], ['L01.453.245.667'], ['E05.393.420.601.550', 'G05.365.590.575', 'G05.558.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of selenium treatment on 6-n-propyl-2-thiouracil-induced impairment of long-term potentiation. | The goal of this study was to evaluate whether sodium selenite could afford protection against the effects of hypothyroidism on long-term potentiation (LTP), which is thought to be the cellular basis for learning and memory. Hypothyroidism was induced in young-adult rats by the administration of 6-n-propyl-2-thiouracil... | ['Animals', 'Excitatory Postsynaptic Potentials', 'Hypothyroidism', 'Long-Term Potentiation', 'Male', 'Propylthiouracil', 'Rats, Wistar', 'Selenium', 'Thyroid Hormones'] | 26,892,488 | [['B01.050'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['C19.874.482'], ['G11.561.638.350'], ['D03.383.742.698.875.842.708'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D01.268.185.850', 'D01.578.700'], ['D06.472.931']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Problems of drug resistance in developing countries--use and abuse of anti-infective agents]. | Widespread use and misuse of anti-infective agents have resulted in a problem of drug resistance linked to treatment of infectious diseases. In developing countries especially, the sale of such drugs is poorly controlled and the pharmaceutical industry is dumping obsolete products. Intensive marketing, lack of diagnost... | ['Anti-Bacterial Agents', 'Developing Countries', 'Diarrhea, Infantile', 'Drug Industry', 'Drug Resistance, Microbial', 'Health Services Misuse', 'Humans', 'Infant', 'Intestinal Diseases, Parasitic', 'Legislation, Drug', 'Malaria', 'Public Policy', 'Respiratory Tract Infections', 'Sexually Transmitted Diseases', 'Tuber... | 1,448,344 | [['D27.505.954.122.085'], ['I01.615.500.300'], ['C23.888.821.214.500'], ['J01.576.655.750'], ['G06.225', 'G07.690.773.984.269'], ['N02.421.380', 'N05.300.150.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C01.610.432', 'C06.405.469.452'], ['I01.880.604.605', 'N03.706.615.402'], ['C01.610.752... | ['Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 |
[A comparison between the revision of Atlanta classification and determinant-based classification in acute pancreatitis]. | Objective: To compare the performance of the revision of Atlanta classification (RAC) and determinant-based classification (DBC) in acute pancreatitis. Methods: Consecutive patients with acute pancreatitis admitted to a single center from January 2001 to January 2015 were retrospectively analyzed. Patients were classif... | ['Acute Disease', 'Area Under Curve', 'Female', 'Hospitalization', 'Humans', 'Length of Stay', 'Male', 'Middle Aged', 'Necrosis', 'Pancreatitis', 'Retrospective Studies', 'Risk Factors', 'Severity of Illness Index', 'Treatment Outcome'] | 29,202,530 | [['C23.550.291.125'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', 'N02.421.585.400.480'], ['M01.060.116.630'], ['C23.550.717'], ['C06.689.750'], ['E05.318.372.500.500.500', 'E05.318... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Regulation of beta-catenin trafficking to the membrane in living cells. | Beta-catenin is a key mediator of the Wnt signaling process and accumulates in the nucleus and at the membrane in response to Wnt-mediated inhibition of GSK-3beta. In this study we used live cell photobleaching experiments to determine the dynamics and rate of recruitment of beta-catenin at membrane adherens junctions ... | ['Amino Acid Substitution', 'Animals', 'Cell Adhesion', 'Cell Line', 'Cell Membrane', 'Cell Movement', 'Fluorescence Recovery After Photobleaching', 'Glycogen Synthase Kinase 3', 'Glycogen Synthase Kinase 3 beta', 'Lithium Chloride', 'Mice', 'Mutagenesis, Site-Directed', 'NIH 3T3 Cells', 'Phosphorylation', 'Protein Tra... | 19,036,347 | [['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['G04.022'], ['A11.251.210'], ['A11.284.149'], ['G04.198', 'G07.568.500.180'], ['E05.196.712.516.600.393'], ['D05.500.117.875', 'D08.811.913.696.620.682.700.429.500', 'D08.811.913.696.620.682.700.646.625', 'D12.644.360.300.500', 'D12.776.476.081.875', 'D12.776.476.3... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Segregation ratios within Segregation Distorter lines of Drosophila melanogaster conform to a beta-binomial distribution. | Segregation Distorter (SD) chromosomes are preferentially recovered from SD/SD+ males due to the dysfunction of sperm bearing the SD+ chromosome. The proportion of offspring bearing the SD chromosome is given the symbol k. The nature of the frequency distribution of k was examined by comparing observed k distributions ... | ['Animals', 'Chromosomes', 'Drosophila melanogaster', 'Genes', 'Male', 'Meiosis', 'Models, Genetic', 'Models, Statistical', 'Phenotype'] | 2,118,469 | [['B01.050'], ['A11.284.187', 'A11.284.430.106.279.345.190', 'G05.360.162'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['G05.360.340.024.340'], ['G04.144.220.220.687', 'G05.113.220.687'], ['E05.599.395.397'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['G05.695']] | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Rapid screening and identification of methicillin-resistant Staphylococcus aureus from clinical samples by selective-broth and real-time PCR assay. | A screening method for methicillin-resistant Staphylococcus aureus (MRSA) by using selective broth and real-time PCR (broth-PCR) was developed and evaluated. The samples (n = 304) were cultured in the broth overnight, followed by nuc gene detection by real-time PCR. nuc-negative samples were further checked for the pre... | ['Bacterial Proteins', 'Bacterial Typing Techniques', 'Carrier Proteins', 'Culture Media', 'Endonucleases', 'Hexosyltransferases', 'Humans', 'Methicillin', 'Methicillin Resistance', 'Microbial Sensitivity Tests', 'Micrococcal Nuclease', 'Muramoylpentapeptide Carboxypeptidase', 'Penicillin-Binding Proteins', 'Penicillin... | 12,843,018 | [['D12.776.097'], ['E01.370.225.875.150.125', 'E05.200.875.150.125'], ['D12.776.157'], ['D27.720.470.305', 'E07.206'], ['D08.811.277.352.355'], ['D08.811.913.400.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.065.589.099.750.500', 'D02.886.108.750.500', 'D03.633.100.300.750.500'], ['G06.099.225.500.600.5... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Paroxysmal nocturnal hemoglobinuria as a marker for clonal myelopathy. | Paroxysmal nocturnal hemoglobinuria (PNH) is recognized as a clonal disorder manifested as increased sensitivity of marrow cells to complement. Case reports have associated this condition with leukemia, myelodysplasia, and myeloproliferative disorders. We identified 47 patients with PNH from 1976 to 1990. In 9 of the 4... | ['Aged', 'Hemoglobinuria, Paroxysmal', 'Hospitals, Group Practice', 'Humans', 'Karyotyping', 'Middle Aged', 'Minnesota', 'Myelodysplastic Syndromes', 'Primary Myelofibrosis', 'Retrospective Studies', 'Survival Rate'] | 1,466,364 | [['M01.060.116.100'], ['C15.378.071.141.560', 'C15.378.190.625.460'], ['N02.278.421.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.385.315', 'E05.242.385.315', 'E05.393.285.475'], ['M01.060.116.630'], ['Z01.107.567.875.350.510', 'Z01.107.567.875.510.510'], ['C15.378.190... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Circulating S100 proteins effectively discriminate SLE patients from healthy controls: a cross-sectional study. | S100 proteins are currently being investigated as potential diagnostic and prognostic biomarkers of several cancers and inflammatory diseases. The aims of this study were to analyse the plasma levels of S100A4, S100A8/9 and S100A12 in patients with incomplete systemic lupus erythematosus (iSLE), in patients with establ... | ['Adult', 'Calgranulin A', 'Calgranulin B', 'Case-Control Studies', 'Cross-Sectional Studies', 'Female', 'Humans', 'Lupus Erythematosus, Systemic', 'Male', 'Middle Aged', 'S100 Calcium-Binding Protein A4', 'S100 Proteins', 'S100A12 Protein', 'Young Adult'] | 30,392,117 | [['M01.060.116'], ['D12.776.157.125.750.500.100', 'D12.776.631.655.500.100', 'D23.050.301.562.100'], ['D12.776.157.125.750.500.200', 'D12.776.631.655.500.200', 'D23.050.301.562.200'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.8... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Linear analysis of carbon-13 chemical shift differences and its application to the detection and correction of errors in referencing and spin system identifications. | Statistical analysis reveals that the set of differences between the secondary shifts of the alpha- and beta-carbons for residues i of a protein (Deltadelta13C(alpha)i - Deltadelta13C(beta)i) provides the means to detect and correct referencing errors for 1H and 13C nuclei within a given dataset. In a correctly referen... | ['Amino Acid Sequence', 'Carbon Isotopes', 'Nuclear Magnetic Resonance, Biomolecular', 'Protein Conformation', 'Proteins', 'Regression Analysis', 'Statistics as Topic'] | 16,041,479 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D01.268.150.075', 'D01.496.123'], ['E05.196.867.519.550'], ['G02.111.570.820.709'], ['D12.776'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['E05.318.740', 'H01.548.832', 'N05.715.360.750', 'N06.850.520.830']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Efficacy & safety of continuous erythropoietin receptor activator (CERA) in treating renal anaemia in diabetic patients with chronic kidney disease not on dialysis. | BACKGROUND & OBJECTIVES: Chronic kidney disease (CKD) patients on dialysis regularly receive erythropoiesis stimulating agent (ESA) for treating renal anaemia during their dialysis unlike those who are not on dialysis. In such patients, the longer acting ESA can be helpful in reducing their frequent visits to the healt... | ['Adult', 'Anemia', 'Blood Pressure', 'Diabetes Mellitus, Type 2', 'Diabetic Nephropathies', 'Erythropoiesis', 'Erythropoietin', 'Female', 'Humans', 'Male', 'Middle Aged', 'Polyethylene Glycols', 'Renal Dialysis', 'Renal Insufficiency, Chronic'] | 24,604,046 | [['M01.060.116'], ['C15.378.071'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C18.452.394.750.149', 'C19.246.300'], ['C12.777.419.192', 'C13.351.968.419.192', 'C19.246.099.875'], ['G04.152.825.414', 'G09.188.343.414'], ['D12.644.276.374.410.240.150', 'D12.776.395.240.150', 'D12.776.467.374.410.240.150', 'D23.529.374... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 |
Nanodroplet-mediated histotripsy for image-guided targeted ultrasound cell ablation. | This paper is an initial work towards developing an image-guided, targeted ultrasound ablation technique by combining histotripsy with nanodroplets that can be selectively delivered to tumor cells. Using extremely short, high-pressure pulses, histotripsy generates a dense cloud of cavitating microbubbles that fractiona... | ['Ablation Techniques', 'Animals', 'Dogs', 'Erythrocytes', 'Fluorocarbons', 'Microscopy, Video', 'Models, Theoretical', 'Molecular Targeted Therapy', 'Nanoparticles', 'Neoplasms', 'Ultrasonic Therapy'] | 24,312,155 | [['E04.014'], ['B01.050'], ['B01.050.150.900.649.313.750.250.216.200'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D02.455.526.510.435'], ['E01.370.350.515.690', 'E05.595.690', 'J01.897.280.500.898.475', 'L01.178.820.090.898.475', 'L01.178.847.823.475'], ['E05.599'], ['E02.319.574'], ['J01.637.512.600'], ['C0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Influence of diesel soot particles and sulfite on functions of polymorphonuclear leukocytes. | Aqueous suspensions of diesel soot particles in combination with sulfite influence certain functions of human polymorphonuclear neutrophils in vitro. Chemiluminescence, generated after activation by opsonized zymosan as well as oxygen uptake were decreased, whereas phagocytosis was increased. An enhancement of degranul... | ['Air Pollutants', 'Cytoplasmic Granules', 'Gasoline', 'Humans', 'Luminescent Measurements', 'Neutrophils', 'Oxygen', 'Phagocytosis', 'Stimulation, Chemical', 'Sulfhydryl Compounds', 'Sulfites', 'Zymosan'] | 2,074,047 | [['D27.888.284.101'], ['A11.284.430.214.190.500', 'A11.284.430.214.190.875.190.190'], ['D20.345.630.540', 'N06.230.132.258.630.540'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.712.516'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', 'A15.382.490.315.583', 'A15.382... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Mechanical properties of dewatered sewage sludge. | The mechanical properties of dewatered, anaerobically digested sewage sludge were determined from soil laboratory tests. The sludge material is largely composed of organic clay sized-particles, a sizable fraction of which is in an active state of biological digestion which can continue over many years under field condi... | ['Bacteria, Anaerobic', 'Chemical Phenomena', 'Chemistry, Physical', 'Conservation of Natural Resources', 'Materials Testing', 'Pressure', 'Sewage', 'Stress, Mechanical', 'Waste Disposal, Fluid', 'Water'] | 15,681,178 | [['B03.130'], ['G02'], ['H01.181.529'], ['J01.256', 'N06.230.080'], ['E05.570'], ['G01.374.715'], ['D20.944.932.500'], ['G01.374.835'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Isolated unilateral absence of left pulmonary artery with peribronchial arteriovenous malformation showing recurrent hemoptysis. | Unilateral absence of a pulmonary artery is an uncommon condition and usually complicated by a cardiac anomaly. Our case is a rare one who showed the absence of the left pulmonary artery with left aortic arch and without cardiac anomaly. He suffered from recurrent hemoptysis and pneumonia since he was 9 months old. Ang... | ['Arteriovenous Malformations', 'Bronchi', 'Bronchial Arteries', 'Child, Preschool', 'Hemoptysis', 'Humans', 'Male', 'Pulmonary Artery', 'Recurrence', 'Subclavian Artery'] | 3,601,465 | [['C14.240.850.750', 'C14.907.150', 'C16.131.240.850.750'], ['A04.411.125'], ['A07.015.114.158'], ['M01.060.406.448'], ['C08.381.348', 'C23.550.414.896', 'C23.888.852.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A07.015.114.715'], ['C23.550.291.937'], ['A07.015.114.839']] | ['Diseases [C]', 'Anatomy [A]', 'Named Groups [M]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genes. | Cell lines stably transfected with metal inducible, MT-fos chimeric genes were used to study the ability of the c-fos gene product, Fos, to act as a transcriptional trans-activator. In 3T3MTfos cells, induction of Fos expression led to specific trans-activation of an AP-1 responsive reporter gene. Induction of Fos expr... | ['Cell Line', 'Enhancer Elements, Genetic', 'Humans', 'Models, Genetic', 'Proto-Oncogene Proteins', 'Proto-Oncogene Proteins c-fos', 'Proto-Oncogenes', 'Transcription Factors', 'Transcription, Genetic', 'Transfection'] | 3,135,940 | [['A11.251.210'], ['G02.111.570.080.689.330', 'G05.360.080.689.330', 'G05.360.340.024.340.137.750.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.395.397'], ['D12.776.624.664.700'], ['D12.776.260.108.765', 'D12.776.624.664.700.179', 'D12.776.660.760', 'D12.776.930.127.765'], ['G05.360.340.024.340.375.... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Self-Assembling Supramolecular Nanostructures Constructed from de Novo Extender Protein Nanobuilding Blocks. | The design of novel proteins that self-assemble into supramolecular complexes is important for development in nanobiotechnology and synthetic biology. Recently, we designed and created a protein nanobuilding block (PN-Block), WA20-foldon, by fusing an intermolecularly folded dimeric de novo WA20 protein and a trimeric ... | ['Chromatography, Gel', 'Escherichia coli', 'Microscopy, Atomic Force', 'Microscopy, Electron, Transmission', 'Nanostructures', 'Protein Denaturation', 'Protein Engineering', 'Protein Refolding', 'Recombinant Proteins', 'Scattering, Small Angle', 'X-Ray Diffraction'] | 29,690,759 | [['E05.196.181.400.250'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['J01.637.512'], ['G01.154.651.750.500', 'G02.111.688.750.500'], ['E05.393.420.601'], ['G01.154.651.501', 'G02.111.688.501'], ['D12.776.828'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Group A streptococcal antibodies in subjects with or without rheumatic fever in areas with high or low incidences of rheumatic fever. | The levels of streptococcal antibody titers in populations with or without rheumatic fever from an area with a relatively high incidence of rheumatic fever and an area with a low incidence of this disease were compared. Streptococcal antibody titers were determined for two populations, each of which included children w... | ['Adolescent', 'Antibodies, Bacterial', 'Child', 'Child, Preschool', 'Florida', 'Grenada', 'Humans', 'Rheumatic Fever', 'Streptococcus pyogenes'] | 12,965,922 | [['M01.060.057'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['M01.060.406'], ['M01.060.406.448'], ['Z01.107.567.875.750.350'], ['Z01.107.084.900.362', 'Z01.639.880.362'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.410.890.731', 'C05.550.114.843', ... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Retrieval of broken iliosacral screws: the power of a push screw. | Percutaneous iliosacral screw fixation is a common technique that is widely used for unstable posterior pelvic ring disruptions. Complications of posterior percutaneous iliosacral screw fixation include implant malpositioning and hardware failure. Removal of iliosacral screws in broken or symptomatic hardware is someti... | ['Adult', 'Bone Screws', 'Device Removal', 'Equipment Failure', 'Female', 'Fracture Fixation, Internal', 'Fractures, Bone', 'Humans', 'Ilium', 'Middle Aged', 'Pelvic Bones', 'Sacroiliac Joint', 'Sacrum', 'Tomography, X-Ray Computed'] | 25,986,663 | [['M01.060.116'], ['E07.695.370.437', 'E07.858.442.660.460.437', 'E07.858.690.725.460.437'], ['E04.199'], ['E05.325'], ['E04.555.300.300'], ['C26.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.043.825.434'], ['M01.060.116.630'], ['A02.835.232.043.825'], ['A02.835.583.707'], ['A02.835.232.834.717'... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Propranolol in chronic schizophrenia: a controlled study in neuroleptic-treated patients. | The effect of propranolol at a dose level of 1,280-1,920 mg per day was studied with a double-blind crossover design in twelve chronic schizophrenics with persistent psychotic symptoms despite maintenance treatment with a depot neuroleptic. By use of a psychiatric rating scale (CPRS), an improvement was seen during the... | ['Adult', 'Antipsychotic Agents', 'Blood Pressure', 'Chronic Disease', 'Clinical Trials as Topic', 'Delayed-Action Preparations', 'Double-Blind Method', 'Drug Synergism', 'Drug Therapy, Combination', 'Female', 'Heart Rate', 'Humans', 'Male', 'Propranolol', 'Schizophrenia'] | 6,107,136 | [['M01.060.116'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C23.550.291.500'], ['E05.318.372.250.250', 'N05.715.360.330.250.250', 'N06.850.520.450.250.250'], ['D26.255.210', 'E02.319.300.253'], ['E05.318.370.300', 'E05.581.50... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Independent induction of senescence by p16INK4a and p21CIP1 in spontaneously immortalized human fibroblasts. | In this work, we address the question of whether replicative senescence can be induced in immortal nontumorigenic human fibroblasts. The immortal fibroblasts used in this study were derived from two Li-Fraumeni (LF) patients who carry in their germ line one wild-type and one mutant p53 allele. Both immortal lines have ... | ['5-Methylcytosine', 'Azacitidine', 'Cell Division', 'Cell Line, Transformed', 'Cellular Senescence', 'CpG Islands', 'Cyclin-Dependent Kinase Inhibitor p16', 'Cyclin-Dependent Kinase Inhibitor p21', 'Cyclins', 'Cytosine', 'DNA Methylation', 'DNA, Complementary', 'Decitabine', 'Gene Expression Regulation', 'Genes, p16',... | 9,486,850 | [['D03.383.742.698.421.500'], ['D02.145.150', 'D03.383.742.680.245.217', 'D13.570.685.245.217', 'D13.570.800.286.300'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210.172'], ['G04.043'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['D12.644.360.225... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A truncated CFTR protein rescues endogenous DeltaF508-CFTR and corrects chloride transport in mice. | Cystic fibrosis (CF) is most frequently associated with deletion of phenylalanine at position 508 (DeltaF508) in the CF transmembrane conductance regulator (CFTR) protein. The DeltaF508-CFTR mutant protein exhibits a folding defect that affects its processing and impairs chloride-channel function. This study aimed to d... | ['Animals', 'Cells, Cultured', 'Chlorides', 'Cystic Fibrosis', 'Cystic Fibrosis Transmembrane Conductance Regulator', 'Epithelial Cells', 'Humans', 'Ion Transport', 'Mice', 'Peptide Fragments'] | 19,620,404 | [['B01.050'], ['A11.251'], ['D01.210.450.150', 'D01.248.497.158.215'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['D12.776.157.530.100.304.500', 'D12.776.157.530.400.175.125', 'D12.776.157.530.450.074.500.500.500.500', 'D12.776.543.550.450.175.125', 'D12.776.543.585.100.304.500', 'D12.776.543.585.40... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Strongyloides hyperinfection syndrome in an immunocompetent host resulting in bandemia and death. | Strongyloides stercoralis infection is usually asymptomatic but can result in a hyperinfection syndrome, most commonly triggered by acquired or iatrogenic immunosuppression. Here, we present a case of a man aged 60 years originally from a strongyloides endemic area with a medical history of alcohol abuse who presents w... | ['Abdominal Pain', 'Animals', 'Fatal Outcome', 'Heart Arrest', 'Humans', 'Hyponatremia', 'Male', 'Middle Aged', 'Strongyloides stercoralis', 'Strongyloidiasis', 'Syndrome'] | 28,331,018 | [['C23.888.592.612.054', 'C23.888.821.030'], ['B01.050'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['C14.280.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.950.620'], ['M01.060.116.630'], ['B01.050.500.500.294.400.875.640.680.70... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Cerebral blood flow in meningitis]. | The cerebral blood flow was studied rheoencephalographically in patients with a grave clinical course of purulent meningitides. The main rheographic parameters showed changes in the dynamics of the disease. It is concluded that there is a lack of coordination between the clinical and morphofunctional cure by the time o... | ['Acute Disease', 'Adolescent', 'Adult', 'Cerebrovascular Circulation', 'Female', 'Hemodynamics', 'Humans', 'Male', 'Meningitis, Meningococcal', 'Middle Aged', 'Plethysmography, Impedance'] | 2,718,431 | [['C23.550.291.125'], ['M01.060.057'], ['M01.060.116'], ['G09.330.100.159'], ['G09.330.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.223.500.750', 'C01.150.252.400.625.549.449', 'C01.207.180.500.750', 'C10.228.228.180.500.750', 'C10.228.614.280.505'], ['M01.060.116.630'], ['E01.370.370.610.610',... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A chromatographic method for the quantification of prostaglandin E(1) and prostaglandin A(1) encapsulated in an intravenous lipid formulation. | Peripheral vascular disease is a common ailment of the aged and diabetic communities. As the numbers of these individuals increase, the need for therapeutic interventions will continue to grow. One of the possible therapies is the use of prostaglandins (PGE(1), prostacyclin and Iloprost) to decrease the vascular tone a... | ['Alprostadil', 'Antiviral Agents', 'Autoanalysis', 'Buffers', 'Chromatography, High Pressure Liquid', 'Injections, Intravenous', 'Liposomes', 'Prostaglandins A', 'Reference Standards', 'Reproducibility of Results', 'Solvents', 'Spectrophotometry, Ultraviolet'] | 11,929,672 | [['D10.251.355.255.550.250.100', 'D10.251.355.325.050', 'D23.469.050.175.725.250.100'], ['D27.505.954.122.388'], ['E05.059'], ['D27.720.470.280'], ['E05.196.181.400.300'], ['E02.319.267.082.750', 'E02.319.267.530.540'], ['D25.479.517', 'D26.255.260.517', 'J01.637.051.479.517', 'J01.637.087.500.517'], ['D10.251.355.255.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Influence of apoptosis (BCL2, FAS), cell cycle (CCND1) and growth factor (EGF, EGFR) genetic polymorphisms on survival outcome: an exploratory study in squamous cell esophageal cancer. | The study aimed at investigating whether genetic polymorphisms in BCL2, FAS, CCND1, EGF and EGFR genes influence the outcome of patients of esophageal squamous cell cancer treated with radiotherapy, with or without chemotherapy. Sixty nine histologically confirmed, previously untreated, patients with a squamous cell es... | ['Adult', 'Aged', 'Aged, 80 and over', 'Apoptosis', 'Carcinoma, Squamous Cell', 'Cell Cycle', 'Cyclin D1', 'Epidermal Growth Factor', 'ErbB Receptors', 'Esophageal Neoplasms', 'Female', 'Humans', 'Male', 'Middle Aged', 'Polymorphism, Genetic', 'Proto-Oncogene Proteins c-bcl-2', 'Survival Analysis', 'Treatment Outcome',... | 17,912,028 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G04.146.954.035'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['G04.144'], ['D12.644.360.262.150.100', 'D12.776.167.218.150.100', 'D12.776.476.262.150.100', 'D12.776.624.664.700.100'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Potential for natural and enhanced attenuation of sulphanilamide in a contaminated chalk aquifer. | Understanding antibiotic biodegradation is important to the appreciation of their fate and removal from the environment. In this research an Isotope Ratio Mass Spectrometry (IRMS) method was developed to evaluate the extent of biodegradation of the antibiotic, sulphanilamide, in contaminated groundwater. Results indict... | ['Biodegradation, Environmental', 'Calcium Carbonate', 'Groundwater', 'Sulfanilamide', 'Sulfanilamides', 'Water Microbiology', 'Water Pollutants, Chemical'] | 29,289,291 | [['N06.230.080.600.500', 'N06.850.460.375.500'], ['D01.146.275', 'D01.200.275.150.150', 'D01.578.200'], ['G01.311.355'], ['D02.065.884.725.885', 'D02.092.146.807.885', 'D02.886.590.700.725.885'], ['D02.065.884.725', 'D02.092.146.807', 'D02.886.590.700.725'], ['H01.158.273.540.274.777', 'N06.850.425.450'], ['D27.888.284... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes. | Global gene expression profiling of highly purified 5q-deleted CD34+CD38(-)Thy1+ cells in 5q- myelodysplastic syndromes (MDSs) supported that they might originate from and outcompete normal CD34+CD38(-)Thy1+ hematopoietic stem cells. Few but distinct differences in gene expression distinguished MDS and normal stem cell... | ['ADP-ribosyl Cyclase 1', 'Aged', 'Aged, 80 and over', 'Antigens, CD34', 'CCAAT-Enhancer-Binding Proteins', 'Cell Lineage', 'Chromosomes, Human, Pair 5', 'Female', 'Gene Expression', 'Gene Expression Profiling', 'Hematopoietic Stem Cells', 'Humans', 'Image Processing, Computer-Assisted', 'In Situ Hybridization, Fluores... | 17,616,640 | [['D08.811.277.450.430.400.060.500', 'D12.776.543.550.045'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.050.301.264.035.134', 'D23.101.100.110.134'], ['D12.776.260.108.124', 'D12.776.660.167', 'D12.776.930.127.124'], ['G04.172', 'G07.345.500.325.180.500', 'G08.686.155', 'G08.686.784.170.104.249'], ['A11.284.18... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
The CYP2D gene subfamily: analysis of the molecular basis of the debrisoquine 4-hydroxylase deficiency in DA rats. | The DA rat has been proposed as an animal model for the human debrisoquine 4-hydroxylase/bufuralol 1'-hydroxylase genetic deficiency. To determine the mechanism of this deficiency, we isolated and sequenced five cDNAs in the CYP2D gene subfamily including a new IID1 allele and two cDNAs of novel P450s, designated IID3 ... | ['Aging', 'Alleles', 'Amino Acid Sequence', 'Animals', 'Base Sequence', 'Biological Evolution', 'Blotting, Northern', 'Blotting, Western', 'Cytochrome P-450 CYP2D6', 'Cytochrome P-450 Enzyme System', 'DNA', 'Disease Models, Animal', 'Female', 'Gene Conversion', 'Gene Expression Regulation, Enzymologic', 'Male', 'Mixed ... | 2,819,073 | [['G07.345.124'], ['G05.360.340.024.340.030'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.045', 'G16.075'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', '... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Transthyretin Amyloidosis: Chaperone Concentration Changes and Increased Proteolysis in the Pathway to Disease. | Transthyretin amyloidosis is a conformational pathology characterized by the extracellular formation of amyloid deposits and the progressive impairment of the peripheral nervous system. Point mutations in this tetrameric plasma protein decrease its stability and are linked to disease onset and progression. Since non-mu... | ['Adult', 'Amino Acid Sequence', 'Amyloid Neuropathies, Familial', 'Blood Proteins', 'Case-Control Studies', 'Electrophoresis, Gel, Two-Dimensional', 'Female', 'Humans', 'Molecular Chaperones', 'Molecular Sequence Data', 'Proteolysis', 'Proteomics', 'Sequence Homology, Amino Acid', 'Spectrometry, Mass, Matrix-Assisted ... | 26,147,092 | [['M01.060.116'], ['G02.111.570.060', 'L01.453.245.667.060'], ['C10.574.500.050', 'C10.668.829.050.050', 'C16.320.400.050', 'C16.320.565.176.050', 'C18.452.648.176.050', 'C18.452.845.500.050.050', 'C18.452.845.500.075.050'], ['D12.776.124'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'],... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Regional contractile responses in pulmonary artery to alpha- and beta-adrenoceptor agonists. | Contractile sensitivity and reactivity to alpha- and beta-adrenoceptor stimulation was studied in incubated rabbit pulmonary artery cylindrical segments of differing diameters. Distinct differences were noted between the responses of extra- and intra-pulmonary pulmonary arteries to norepinephrine and isoproterenol. The... | ['Animals', 'Cocaine', 'Hydrocortisone', 'In Vitro Techniques', 'Isoproterenol', 'Male', 'Muscle Contraction', 'Muscle, Smooth, Vascular', 'Norepinephrine', 'Organ Specificity', 'Phentolamine', 'Propranolol', 'Pulmonary Artery', 'Rabbits'] | 3,621,064 | [['B01.050'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['E05.481'], ['D02.033.100.291.439', 'D02.092.063.291.439', 'D02.092.311.649', 'D02.455.426.559.389.657.166.175.649'], ['G11.427.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Coarse-grained simulations of moderately entangled star polyethylene melts. | In this paper, a previous coarse-grain model [J. T. Padding and W. J. Briels, J. Chem. Phys. 117, 925 (2002)] to simulate melts of linear polymers has been adapted to simulate polymers with more complex hierarchies. Bond crossings between highly coarse-grained soft particles are prevented by applying an entanglement al... | ['Algorithms', 'Freezing', 'Molecular Dynamics Simulation', 'Polyethylene', 'Rheology'] | 23,822,279 | [['G17.035', 'L01.224.050'], ['G01.645.500', 'G01.906.595.272.437', 'G02.734.466'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D02.455.326.271.665.550.500', 'D05.750.716.507.500', 'D25.720.716.507.500', 'J01.637.051.720.716.507.500'], ['E05.830', 'H01.671.808']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Children with specific reading retardation--early determinants and long-term outcome. | In a prospective epidemiological longitudinal study of children (n = 399) from age 8 to 18 years, children with specific reading retardation (n = 37) were identified by the modified Research Diagnostic Criteria of ICD-10. The group with specific reading retardation was compared with a group with other specific developm... | ['Adolescent', 'Age Factors', 'Child', 'Child Behavior Disorders', 'Comorbidity', 'Developmental Disabilities', 'Dyslexia', 'Germany', 'Humans', 'Longitudinal Studies', 'Mental Disorders', 'Prospective Studies', 'Risk Factors', 'Writing'] | 7,521,559 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.406'], ['F03.625.141'], ['N05.715.350.225', 'N06.850.490.687'], ['F03.625.421'], ['C10.597.606.150.500.300', 'C10.597.606.150.550.200', 'C23.888.592.604.150.500.300', 'C23.888.592.604.150.550.200', 'F03.625.562.400'], ['Z01.542.315'], ['B01.050.150.900... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Translational selection on codon usage in the genus Aspergillus. | Aspergillus is a genus of mold fungi that includes more than 200 described species. Many members of the group are relevant pathogens and other species are economically important. Only one species has been analyzed for codon usage, and this was performed with a small number of genes. In this paper, we report the codon u... | ['Aspergillus', 'Codon', 'Conserved Sequence', 'Evolution, Molecular', 'Genome, Fungal', 'Models, Genetic', 'Mutation', 'Phylogeny', 'Protein Biosynthesis', 'RNA, Fungal', 'RNA, Transfer', 'Selection, Genetic', 'Species Specificity'] | 22,742,978 | [['B01.300.381.081'], ['D13.444.735.544.355', 'G05.360.335.355', 'G05.360.340.024.340.137.190'], ['G02.111.570.580'], ['G05.045.250', 'G16.075.250'], ['G05.360.340.358.365'], ['E05.599.395.397'], ['G05.365.590'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G02.111.660.871', 'G03.734.871', 'G05.297.670'], ['D13.444.735... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Time-resolved fluorescence line-narrowing of Eu3+ in biocompatible eutectic glass-ceramics. | The spectroscopic properties of Eu(3+) in biocompatible glass and glass-ceramic eutectic rods of composition 0.8CaSiO(3)-0.2Ca(3)(PO(4))(2) doped with 0.5 wt% of Eu(2)O(3) are investigated to explore their potential applications as optical probes. The samples were obtained by the laser floating zone technique. Dependin... | ['Biocompatible Materials', 'Calcium Phosphates', 'Ceramics', 'Europium', 'Luminescence', 'Spectrometry, Fluorescence', 'Temperature', 'Time Factors'] | 23,482,227 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D01.029.260.700.675.374.075', 'D01.146.360', 'D01.695.625.675.650.075'], ['J01.637.153'], ['D01.268.558.362.468', 'D01.552.550.399.468'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G01.750.250.650.665', 'G01.750.770.578.665'], ['E05.196.712.516.600.676', 'E05.1... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Auto-fluorescence emitted from the cell residues preserved in human tissues of medieval Korean mummies. | As a significant association has been established between residual ancient DNA (aDNA) and histological preservation, the morphological identification or confirmation of preserved cell residue in ancient tissues would greatly facilitate aDNA studies and enhance the definitiveness of their conclusions. However, morpholog... | ['Cartilage', 'Cartilage, Articular', 'Chondrocytes', 'Fluorescence', 'Humans', 'Kidney', 'Lung', 'Microdissection', 'Microscopy, Confocal', 'Microscopy, Electron, Scanning', 'Microscopy, Fluorescence', 'Mummies', 'Paleopathology'] | 20,456,521 | [['A02.165', 'A10.165.382'], ['A02.165.407.150', 'A02.835.583.192'], ['A11.329.171'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A05.810.453'], ['A04.411'], ['E01.370.225.500.620.520', 'E01.370.225.750.600.520', 'E01.370.225.998.221.580', 'E04.221.580', 'E... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Rescue of a maize mitochondrial cytochrome oxidase mutant by tissue culture. | The maize NCS6 mitochondrial mutation is a partial deletion of the cytochrome oxidase subunit 2 gene (cox2) that survives heteroplasmically in the plant. Mutant mitochondria segregate from normal mitochondria during somatic development giving rise to defective sectors on the plants, including areas of kernel abortion o... | ['Base Sequence', 'Cells, Cultured', 'DNA Primers', 'Electron Transport Complex IV', 'Genes, Plant', 'Macromolecular Substances', 'Mitochondria', 'Molecular Sequence Data', 'Mutation', 'Polymerase Chain Reaction', 'Seeds', 'Sequence Deletion', 'Zea mays'] | 7,849,753 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D05.500.562.374', 'D08.811.600.250.687', 'D08.811.682.285', 'D12.776.157.530.450.250.875.304', 'D12.776.543.277.687', 'D12.776.543.585.450.250.875.484'], ['G05.360.340.024.340.393', 'G0... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Fifty-two consecutive aortic valve replacements employing local deep hypothermia. | From August, 1972, to May, 1974, 52 consecutive aortic valves were replaced with the Bj?rk-Shiley tilting-disc prosthesis. The hospital mortality was zero. Patients ranged in age from 14 to 77 years, and 19 patients had simultaneous correction of associated cardiac lesions. Using techniques of low flow and local deep h... | ['Adolescent', 'Adult', 'Aged', 'Aortic Aneurysm', 'Aortic Valve', 'Coronary Artery Bypass', 'Coronary Vessels', 'Female', 'Florida', 'Follow-Up Studies', 'Heart Valve Prosthesis', 'Humans', 'Hypothermia, Induced', 'Ischemia', 'Male', 'Middle Aged', 'Mitral Valve', 'Perfusion', 'Suture Techniques', 'Time Factors'] | 1,093,493 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C14.907.055.239', 'C14.907.109.139'], ['A07.541.510.110'], ['E04.100.376.719.332', 'E04.100.814.868.750', 'E04.928.220.520.220'], ['A07.015.114.269', 'A07.015.908.194'], ['Z01.107.567.875.750.350'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Comparison of survey and physician claims data for detecting hypertension. | Using linked data from the Manitoba (Canada) Heart Health Survey (MHHS) and physician service claims files we assessed the degree to which self-reported hypertension and clinically measured hypetension agreed with physician claims hypertension, and examined the likely sources of disagreement. The overall agreement betw... | ['Adult', 'Female', 'Health Surveys', 'Humans', 'Hypertension', 'Insurance, Health', 'Logistic Models', 'Male', 'Middle Aged', 'Odds Ratio', 'Physicians', 'Prevalence'] | 9,250,269 | [['M01.060.116'], ['E05.318.308.980.438', 'N05.715.360.300.800.438', 'N06.850.520.308.980.438'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['N03.219.521.576.343'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Evaluation for magnesium and vitamin B6 supplementation among Polish elite athletes. | Contemporary sport requires a lot of effort from sportsmen, frequently exceeding their maximum physical and mental efficiency. Athletes often report poor dietary habits and reach for magnesium and vitamin B supplements to avoid dietary deficiencies. The aim of this study was to determine magnesium and vitamin B6 conten... | ['Adult', 'Athletes', 'Dietary Supplements', 'Energy Intake', 'Feeding Behavior', 'Female', 'Humans', 'Magnesium', 'Male', 'Nutritional Requirements', 'Nutritional Status', 'Poland', 'Vitamin B 6', 'Young Adult'] | 22,435,297 | [['M01.060.116'], ['M01.072'], ['G07.203.300.456', 'J02.500.456'], ['G07.203.650.240.340'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.552.437', 'D01.268.557.500', 'D01.552.547.500'], ['G07.203.650.620'], ['G07.203.650.650', 'N01.224.425.525'], ['Z0... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
A novel mechanism of G protein-dependent phosphorylation of vasodilator-stimulated phosphoprotein. | Vasodilator-stimulated phosphoprotein (VASP) is a major substrate of protein kinase A (PKA). Here we described the novel mechanism of VASP phosphorylation via cAMP-independent PKA activation. We showed that in human umbilical vein endothelial cells (HUVECs) alpha-thrombin induced phosphorylation of VASP. Specific inhib... | ['Actins', 'Animals', 'COS Cells', 'Catalytic Domain', 'Cell Adhesion Molecules', 'Cell Line', 'Cells, Cultured', 'Cyclic AMP-Dependent Protein Kinases', 'Cytoskeleton', 'Electrophoresis, Polyacrylamide Gel', 'Endothelium, Vascular', 'Enzyme Activation', 'Enzyme Inhibitors', 'GTP-Binding Protein alpha Subunits, G12-G13... | 16,046,415 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['A11.251.210.172.500', 'A11.329.228.220'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['A11.251.210'], ['A11.251'], ['D08.811.913.696.620.682.700.150.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mortality from chronic obstructive pulmonary disease and pleural mesothelioma in an area contaminated by natural fiber (fluoro-edenite). | OBJECTIVES: The purpose of the present study was to investigate the association between mortality from chronic obstructive pulmonary disease (COPD) and exposure to fluoro-edenite, a newly discovered amphibolic fiber found in Biancavilla (Sicily), a municipality on the slope of the Etna volcano, where a high mortality f... | ['Adult', 'Aged', 'Bias', 'Environmental Exposure', 'Female', 'Humans', 'Male', 'Mesothelioma', 'Middle Aged', 'Mineral Fibers', 'Pleural Neoplasms', 'Pulmonary Disease, Chronic Obstructive', 'Regression Analysis', 'Risk Factors', 'Rural Health', 'Sex Factors', 'Sicily', 'Urban Health', 'Volcanic Eruptions'] | 15,250,654 | [['M01.060.116'], ['M01.060.116.100'], ['N05.715.350.150', 'N06.850.490.500'], ['N06.850.460.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.470.035.510', 'C04.557.470.660.510'], ['M01.060.116.630'], ['D01.578.500'], ['C04.588.894.797.640', 'C08.528.694', 'C08.785.640'], ['C08.381.495.389'], ['E05.318... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A Pro504 --> Ser substitution in the beta-subunit of beta-hexosaminidase A inhibits alpha-subunit hydrolysis of GM2 ganglioside, resulting in chronic Sandhoff disease. | The GM2 gangliosidoses are caused by mutations in the genes encoding the alpha- (Tay-Sachs) or beta- (Sandhoff) subunits of heterodimeric beta-hexosaminidase A (Hex A), or the GM2 activator protein (AB variant), a substrate-specific co-factor for Hex A. Although the active site associated with the hydrolysis of GM2 gan... | ['Amino Acid Substitution', 'Animals', 'Base Sequence', 'CHO Cells', 'Chronic Disease', 'Cricetinae', 'DNA Primers', 'G(M2) Ganglioside', 'Heterozygote', 'Hexosaminidase A', 'Hexosaminidase B', 'Homozygote', 'Humans', 'Hydrolysis', 'Proline', 'Sandhoff Disease', 'Serine', 'beta-N-Acetylhexosaminidases'] | 9,694,901 | [['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.200', 'A11.436.155'], ['C23.550.291.500'], ['B01.050.150.900.649.313.992.635.075.250'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D09.400.410.420.025.475.400', 'D10.390.470.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Application of empirical mode decomposition with local linear quantile regression in financial time series forecasting. | This paper mainly forecasts the daily closing price of stock markets. We propose a two-stage technique that combines the empirical mode decomposition (EMD) with nonparametric methods of local linear quantile (LLQ). We use the proposed technique, EMD-LLQ, to forecast two stock index time series. Detailed experiments are... | ['Algorithms', 'Commerce', 'Computer Simulation', 'Forecasting', 'Regression Analysis'] | 25,140,343 | [['G17.035', 'L01.224.050'], ['J01.219'], ['L01.224.160'], ['I01.320'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 |
Conformational-energy studies of tetrapeptide opiates. Candidate active and inactive conformations. | The conformational behavior of four tetrapeptide enkephalin analogues (Tyr-Gly-Gly-Phe-OH, Tyr-Gly-Gly-Phe-NH2, Tyr-D-Ala-Gly-Phe-NH2, and Tyr-D-Ala-Gly-(NMe)Phe-NH2) was examined to identify conformations that are active and inactive at the opiate analgesic receptor. By using an empirical energy program, conformationa... | ['Amino Acid Sequence', 'Chemical Phenomena', 'Chemistry, Physical', 'Enkephalins', 'Hydrogen-Ion Concentration', 'Models, Molecular', 'Oligopeptides', 'Protein Conformation', 'Quantum Theory', 'Thermodynamics', 'Tyramine'] | 7,155,126 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02'], ['H01.181.529'], ['D12.644.400.575.281', 'D12.776.631.650.575.281'], ['G02.300'], ['E05.599.595'], ['D12.644.456'], ['G02.111.570.820.709'], ['H01.671.579.800'], ['G01.906'], ['D02.092.211.215.811']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Infrared imaging with a wavefront-coded singlet lens. | We describe the use of wavefront coding for the mitigation of optical aberrations in a thermal imaging system. Diffraction-limited imaging is demonstrated with a simple singlet which enables an approximate halving in length and mass of the optical system compared to an equivalent two-element lens. | ['Equipment Design', 'Glass', 'Image Processing, Computer-Assisted', 'Infrared Rays', 'Lenses', 'Optics and Photonics', 'Signal Processing, Computer-Assisted', 'Software', 'Spectrophotometry, Infrared'] | 19,997,351 | [['E05.320'], ['J01.637.437'], ['L01.224.308'], ['G01.358.500.505.650.552', 'G01.590.540.552', 'G01.750.250.650.552', 'G01.750.770.578.552', 'G16.500.275.063.725.525.400', 'G16.500.750.775.525.400', 'N06.230.300.100.725.525.400'], ['E07.632.500'], ['H01.671.617', 'J01.293.688'], ['L01.224.800'], ['L01.224.900'], ['E05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 |
Oxygen supply to the liver in patients with alcoholic liver disease assessed by organ-reflectance spectrophotometry. | In the present study we have investigated hepatic hemodynamics in patients with alcoholic liver disease using reflectance spectrophotometry and the hydrogen clearance method. Analysis of 38 cases has shown that estimated regional hepatic-tissue hemoglobin concentration, expressed as a difference in absorbance between 5... | ['Absorption', 'Adult', 'Hemoglobins', 'Humans', 'Liver', 'Liver Circulation', 'Liver Diseases, Alcoholic', 'Middle Aged', 'Oxygen', 'Oxygen Consumption', 'Spectrophotometry'] | 3,972,232 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['M01.060.116'], ['D12.776.124.400', 'D12.776.422.316.762'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['G09.330.100.881.552'], ['C06.552.645', 'C25.775.100.087.645'], ['M01.060.116.630'], ['D01.268.185.550', 'D01.362.670'], ['G03... | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of limestone addition and sintering on heavy metal leaching from hazardous waste incineration slag. | Hazardous waste incineration (HWI) in rotary kilns and the disposal of the residual slag on landfills play an important role in German waste treatment. In order to save disposal costs the elution behaviour of HWI-slag should be further optimised. Quality-improved slag may be disposed off on cheaper landfill sites still... | ['Calcium Carbonate', 'Cost Control', 'Hazardous Waste', 'Incineration', 'Metals, Heavy', 'Models, Theoretical', 'Refuse Disposal', 'Temperature'] | 11,952,178 | [['D01.146.275', 'D01.200.275.150.150', 'D01.578.200'], ['N03.219.151.160'], ['D20.944.380', 'D27.888.426.500', 'N06.850.460.710.380'], ['N06.850.860.510.900.600.500'], ['D01.268.556', 'D01.552.544'], ['E05.599'], ['N06.850.780.200.800.800.700', 'N06.850.860.510.900.600'], ['G01.906.595', 'G16.500.275.063.725.710', 'G1... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The role of parliamentarians in promoting sexual and reproductive health and rights. | Parliamentarians are central to the full implementation of the International Conference on Population and Development Programme of Action (ICPD PoA). We promote, review, and adopt sexual and reproductive health and rights (SRHR) legislation, including budget appropriations. Parliamentarians also approve policies formul... | ['Budgets', 'Health Policy', 'Health Services Accessibility', 'Humans', 'Policy Making', 'Politics', 'Reproductive Rights', "Women's Health", "Women's Health Services", "Women's Rights"] | 19,535,070 | [['N03.219.463.060'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.706.742'], ['I01.738'], ['I01.880.604.473.675', 'N03.706.437.675'], ['N01.400.900'], ['N02.421.920'], ['I01.880.604.473.850', 'N03.7... | ['Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Patterns of inpatient and outpatient care for asthma in Erie and Niagara Counties, western New York State. | The prevalence of asthma, as well as the morbidity and mortality due to asthma, has increased in the United States, especially among poor minority subpopulations. The causes of these increases are complex and not well understood. Our findings from an analysis of emergency room (ER) visits and hospitalizations for Erie ... | ['Adolescent', 'Adult', 'Asthma', 'Emergency Service, Hospital', 'Female', 'Hospitalization', 'Humans', 'Insurance, Hospitalization', 'Male', 'Middle Aged', 'New York', 'Patient Admission', 'Sex Factors'] | 11,321,686 | [['M01.060.057'], ['M01.060.116'], ['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343.492'], ['M01.060.116.630'], [... | ['Named Groups [M]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Is decedent race an independent predictor of organ donor consent or merely a surrogate marker of socioeconomic status? | BACKGROUND: Studies have demonstrated that African American race is a strong predictor of nondonation. However, it is often and correctly argued that African American race is a crude explanatory variable that is a surrogate marker of socioeconomic status, education, and access to health care. We hypothesized that, when... | ['Adolescent', 'Adult', 'African Americans', 'Aged', 'Biomarkers', 'Educational Status', 'European Continental Ancestry Group', 'Female', 'Humans', 'Income', 'Logistic Models', 'Male', 'Marital Status', 'Middle Aged', 'Residence Characteristics', 'Social Class', 'Tissue Donors'] | 23,018,878 | [['M01.060.057'], ['M01.060.116'], ['M01.686.508.100.100', 'M01.686.754.100'], ['M01.060.116.100'], ['D23.101'], ['N01.824.196'], ['M01.686.508.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.417'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Genetic problems of cattle resistance to brucellosis. I. The age of having the disease, the paternal influence and strain affiliation in the incidence of brucellosis morbidity]. | From 2810 animals of black-and-white breed of Novosibirsk region diagnosed, 31% fell ill. Young animals were found to be more resistant to brucellosis. It is evidently more probable that they can reach the reproductive age. Intrapopulation hereditary heterogeneity to brucellosis was found. The progeny of certain bulls ... | ['Aging', 'Animals', 'Breeding', 'Brucellosis, Bovine', 'Cattle', 'Disease Susceptibility', 'Fathers', 'Female', 'Male', 'Siberia'] | 7,195,859 | [['G07.345.124'], ['B01.050'], ['E05.820.150', 'G05.090'], ['C01.150.252.400.167.322', 'C22.021.322', 'C22.196.148'], ['B01.050.150.900.649.313.500.380.271'], ['C23.550.291.687', 'G07.100.250'], ['F01.829.263.500.320.100', 'I01.880.853.150.500.340.210', 'M01.620.390'], ['Z01.252.122.500.500']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 |
Intrauterine intervention in a case of recurrent meconium peritonitis. | We present a case of recurrent meconium peritonitis detected in the second trimester and treated by intrauterine intervention. Antenatal ultrasound findings included fetal ascites and intra-abdominal calcification. Aspiration of fetal ascites under ultrasound guidance and determination of the bilirubin concentration es... | ['Adult', 'Ascites', 'Female', 'Fetal Diseases', 'Humans', 'Infant, Newborn', 'Male', 'Meconium', 'Peritonitis', 'Pregnancy', 'Pregnancy Outcome', 'Pregnancy Trimester, Second', 'Prenatal Diagnosis', 'Recurrence', 'Ultrasonography, Prenatal', 'Uterus'] | 7,899,274 | [['M01.060.116'], ['C23.550.081'], ['C13.703.277', 'C16.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['A12.459.529', 'A16.378.529'], ['C01.463.600', 'C06.844.640'], ['G08.686.784.769'], ['E01.789.700', 'G08.686.784.769.496'], ['G08.686.707.490'], ['E01.370.378.630'], ['C23.550.291.937'],... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Predictors of dementia caregiver depressive symptoms in a population: the Cache County dementia progression study. | OBJECTIVES: Previous research has consistently reported elevated rates of depressive symptoms in dementia caregivers, but mostly with convenience samples. This study examined rates and correlates of depression at the baseline visit of a population sample of dementia caregivers (N = 256).METHOD: Using a modified version... | ['Adaptation, Psychological', 'Aged', 'Aged, 80 and over', 'Caregivers', 'Dementia', 'Depression', 'Disease Progression', 'Female', 'Health Status', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Psychiatric Status Rating Scales', 'Quality of Life', 'Social Support', 'Stress, Psy... | 23,241,850 | [['F01.058'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['C10.228.140.380', 'F03.615.400'], ['F01.145.126.350'], ['C23.550.291.656'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N0... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Humanities [K]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
The role of autopsy in death resulting from trauma. | This study examined the difference between clinical impressions and autopsy findings in a group of patients dying on a university surgical service after blunt injury, penetrating injury, or thermal burns. Of 215 patients dying between the years 1984 and 1988, 212 were included in this study (autopsy rate, 98.6%). Major... | ['Adult', 'Aged', 'Autopsy', 'Burns', 'Child', 'Diagnostic Errors', 'Emergency Medical Services', 'Female', 'Humans', 'Male', 'Middle Aged', 'Quality Assurance, Health Care', 'Texas', 'Wounds and Injuries', 'Wounds, Nonpenetrating', 'Wounds, Penetrating'] | 2,388,303 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['C26.200'], ['M01.060.406'], ['E01.354', 'N02.421.450.280'], ['N02.421.297'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['N04.761.700', 'N05.700'], ['Z01.107.567.875.760.750'], ['C26'], ['C26.974'], ['... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A formal theory for spatial representation and reasoning in biomedical ontologies. | OBJECTIVE: The objective of this paper is to demonstrate how a formal spatial theory can be used as an important tool for disambiguating the spatial information embodied in biomedical ontologies and for enhancing their automatic reasoning capabilities.METHOD AND MATERIALS: This paper presents a formal theory of parthoo... | ['Anatomy', 'Artificial Intelligence', 'Computational Biology', 'Humans', 'Informatics', 'Logic', 'Vocabulary, Controlled'] | 16,249,077 | [['H01.158.100'], ['G17.035.250', 'L01.224.050.375'], ['H01.158.273.180', 'L01.313.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.313'], ['K01.752.448'], ['L01.453.245.945']] | ['Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Humanities [K]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Prognostic significance of peripheral blood S + G2/M phase size in adult acute non-lymphoblastic leukaemia. | Flow cytometric analysis of peripheral blood (PB) S + G2/M phase size was performed in 73 adult patients with untreated acute non-lymphoblastic leukaemia, to assess whether the results may correlate to response rate and patient prognosis. All patients were treated with the same induction chemotherapy regimen: ARA-C alo... | ['Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Flow Cytometry', 'Humans', 'Interphase', 'Leukemia, Myeloid, Acute', 'Male', 'Middle Aged', 'Mitosis', 'Prognosis'] | 2,767,239 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G04.144.500'], ['C04.557.337.539.2... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Behavioural profile of exendin-4/naltrexone dose combinations in male rats during tests of palatable food consumption. | RATIONALE: The glucagon-like peptide 1 receptor (GLP-1R) agonist exendin-4 potently suppresses food intake in animals and humans. However, little is known about the behavioural specificity of this effect either when administered alone or when co-administered with another anorectic agent.OBJECTIVES: The present study ch... | ['Animals', 'Appetite Depressants', 'Behavior, Animal', 'Body Weight', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Eating', 'Exenatide', 'Feeding Behavior', 'Male', 'Naltrexone', 'Peptides', 'Rats', 'Venoms'] | 24,682,505 | [['B01.050'], ['D27.505.954.203.155'], ['F01.145.113'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['G07.203.650.283', 'G10.261.330'], ['D12.644.187', 'D20.888.300', 'D23.946.833.300'],... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A child with rapidly progressive necrotizing group a streptococcal Tenon's capsule infection one day after strabismus surgery. | Periorbital infections after strabismus surgery are rare. We describe the first reported case of necrotizing group A streptococcal infection of the conjunctiva and Tenon's capsule complicating uneventful strabismus surgery in a 23-month-old boy, successfully managed with conservative intraoperative debridement and with... | ['Amoxicillin-Potassium Clavulanate Combination', 'Anti-Bacterial Agents', 'Conjunctivitis, Bacterial', 'Esotropia', 'Eye Infections, Bacterial', 'Fasciitis, Necrotizing', 'Humans', 'Infant', 'Male', 'Oculomotor Muscles', 'Ophthalmologic Surgical Procedures', 'Penicillin G', 'Streptococcal Infections', 'Streptococcus p... | 26,486,034 | [['D02.065.589.099.374.160.060', 'D02.065.589.099.750.750.050.050.060', 'D02.886.108.750.750.050.050.060', 'D03.633.100.300.374.160.060', 'D03.633.100.300.750.750.050.050.500', 'D26.310.102'], ['D27.505.954.122.085'], ['C01.150.252.289.225', 'C01.375.354.220', 'C11.187.183.220', 'C11.294.354.220'], ['C10.292.562.887.30... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
ERCP: Complications and prophylaxis a controlled study. | Prophylactic measures for the prevention of complications (pancreatitis, pancreatic and biliary sepsis) after an ERCP examination were investigated in a controlled study. A total of 118 patients were selected at random and divided into three groups by post-ERCP treatment (Group A: no treatment, Group B: oral prophylaxi... | ['Amylases', 'Bacterial Infections', 'Bile Duct Diseases', 'Cholangiopancreatography, Endoscopic Retrograde', 'Humans', 'Leukocyte Count', 'Pancreatic Diseases'] | 6,161,804 | [['D08.811.277.450.066'], ['C01.150.252'], ['C06.130.120'], ['E01.370.350.700.715.200.200', 'E01.370.372.200.200', 'E01.370.372.250.200', 'E01.370.388.250.250.160', 'E04.210.240.160', 'E04.502.250.250.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of cyclophosphamide metabolites by gas chromatography and thermionic specific detection. Interindividual differences in hepatic biotransformation of cyclophosphamide in man in vitro. | Sensitive methods for the determination of the cyclophosphamide metabolites nornitrogen mustard, 4-ketocyclophosphamide and carboxyphosphamide are presented. After liquid-liquid extraction and derivatization, the metabolites are determined by gas chromatography and thermionic specific detection. The methods were used t... | ['Chromatography, Gas', 'Cyclophosphamide', 'Humans', 'Liver', 'Nitrogen', 'Phosphoramide Mustards'] | 8,611,954 | [['E05.196.181.349'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['D01.268.604', 'D01.362.625'], ['D02.455.526.728.650.730', 'D02.705.672.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Evaluation of second look laparotomy in the management of epithelial ovarian tumors. 88 interventions performed at the Dijon CAC between 1979 and 1990]. | OBJECTIVE: To evaluate the second look laparotomy in the treatment and management of epithelial ovarian carcinoma.DESIGN: A retrospective study (1979-1990).SETTING: Centre G.-F. Leclerc, Dijon.SUBJECTS: 88 patients underwent a 2e look laparotomy during the period. Most of them (69.3%) were stage III or IV cancers.RESUL... | ['Actuarial Analysis', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'France', 'Humans', 'Middle Aged', 'Neoplasm Staging', 'Neoplasms, Glandular and Epithelial', 'Ovarian Neoplasms', 'Predictive Value of Tests', 'Prognosis', 'Reoperation', 'Retrospective Studies', 'Surgicenters', 'Survival Analysis', '... | 8,132,958 | [['E05.318.740.100', 'N05.715.360.750.100', 'N06.850.520.830.100'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.542.286'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789.625'], ['C04.557.470'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Selenium supplementation does not alter platelet activation in subjects with normal selenium status. | The effect of Se supplementation on the plasma concentrations of platelet specific proteins, beta-thromboglobulin (beta TG) and platelet factor 4 (PF4), was determined in twenty young women with normal selenium (Se) status using a double blind protocol. Selenium supplementation for 4 weeks (150 micrograms/day), did not... | ['Adult', 'Dose-Response Relationship, Drug', 'Female', 'Glutathione', 'Humans', 'Nutritional Status', 'Platelet Activation', 'Platelet Factor 4', 'Selenium', 'Uric Acid', 'Vitamin A', 'Vitamin E', 'beta-Thromboglobulin'] | 2,532,184 | [['M01.060.116'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.644.456.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.203.650.650', 'N01.224.425.525'], ['G09.188.390.600'], ['D12.644.276.374.200.120.900', 'D12.776.124.125.720', 'D12.776.467.374.200.120.900', 'D23.119.940', 'D23.125.300.120.900', 'D23.46... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Macromolecule absorption and cortisol secretion in newborn calves derived from in vitro produced embryos. | Earlier reports indicate that calves derived from in vitro produced (IVP) embryos are more susceptible to neonatal disease than calves produced after artificial insemination (AI) or natural mating. The aims of the present study were to investigate whether calves born after IVP embryos show an altered macromolecule abso... | ['Absorption', 'Acidosis', 'Adrenocorticotropic Hormone', 'Animals', 'Animals, Newborn', 'Cattle', 'Colostrum', 'Culture Techniques', 'Fertilization in Vitro', 'Gestational Age', 'Hydrocortisone', 'Hydrogen-Ion Concentration', 'Immunoglobulin G', 'Kinetics', 'Serum Albumin', 'Swine'] | 11,841,902 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['C18.452.076.176'], ['D06.472.699.327.935.531.500', 'D06.472.699.631.525.600.531.500', 'D12.644.400.400.935.531.500', 'D12.644.548.365.935.531.500', 'D12.644.548.691.525.690.531.500', 'D12.776.631.650.405.935.531.500'], ['B01.050'], ['B01.050.050.28... | ['Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Response of rock-fissure seepage to snowmelt in Mount Taihang slope-catchment, North China. | The complex physiographic and hydrogeological systems of mountain terrains facilitate intense rock-fissure seepages and multi-functional ecological interactions. As mountain eco-hydrological terrains are the common water sources of river basins across the globe, it is critical to build sufficient understanding into the... | ['China', 'Geological Phenomena', 'Snow', 'Soil', 'Time Factors', 'Water Movements', 'Water Supply'] | 23,128,629 | [['Z01.252.474.164'], ['G01.311'], ['G16.500.175.867', 'G16.500.275.063.725.480', 'G16.500.750.775.480', 'N06.230.300.100.725.480'], ['D20.721', 'G01.311.820', 'G16.500.275.815', 'N06.230.600'], ['G01.910.857'], ['G16.500.971', 'N06.230.132.644.750', 'N06.230.850'], ['J01.293.821.500']] | ['Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Risk factors for early failure of native arteriovenous fistulas. | INTRODUCTION: Current guidelines recommend native arteriovenous fistulas (AVF) as the vascular access of choice for hemodialysis on account of the lower incidence of complications. However, this kind of vascular access has a high rate of early failure (early thrombosis or non-maturation). Our aim was to examine whether... | ['Adult', 'Age Factors', 'Aged', 'Arteriovenous Shunt, Surgical', 'Diabetes Complications', 'Female', 'Humans', 'Logistic Models', 'Male', 'Middle Aged', 'Renal Dialysis', 'Retrospective Studies', 'Risk Factors', 'Sex Factors', 'Ultrasonography, Doppler, Duplex'] | 15,886,495 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E04.035.087', 'E04.100.814.868.249'], ['C19.246.099'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.75... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Simulated environmental risk estimation of engineered nanomaterials: a case of cosmetics in Johannesburg City. | This paper attempts to quantify the potential risks posed by engineered nanomaterials (ENMs) to the aquatic and terrestrial ecosystems from cosmetic-based nanoproducts. The predicted environmental concentrations (PEC) were modelled for the silver (nAg) and titanium dioxide (nTiO(2)) nanoparticles embedded in cosmetic n... | ['Computer Simulation', 'Cosmetics', 'Environmental Monitoring', 'Environmental Pollutants', 'Models, Theoretical', 'Nanostructures', 'Risk Assessment', 'Silver', 'South Africa', 'Titanium', 'Water Pollutants, Chemical'] | 21,148,195 | [['L01.224.160'], ['D27.720.269', 'J01.516.213'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D27.888.284'], ['E05.599'], ['J01.637.512'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.850.520.830.600.800.715'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.54... | ['Information Science [L]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 |
Contrast-to-noise ratio of multiple slice spin lock technique: prospects for liver imaging. | Spin lock (SL) MRI technique has been demonstrated to provide similar lesion/liver contrast to conventional MR technique. Multiple slice SL technique allows a large number of slices to be collected within a given repetition time due to the short echo time. In addition, the short echo time reduces movement and susceptib... | ['Adult', 'Algorithms', 'Female', 'Humans', 'Liver', 'Magnetic Resonance Imaging', 'Magnetic Resonance Spectroscopy', 'Male', 'Middle Aged'] | 14,623,779 | [['M01.060.116'], ['G17.035', 'L01.224.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['E01.370.350.825.500'], ['E05.196.867.519'], ['M01.060.116.630']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Retroposition and evolution of the DNA-binding motifs of YY1, YY2 and REX1. | YY1 is a DNA-binding transcription factor found in both vertebrates and invertebrates. Database searches identified 62 YY1 related sequences from all the available genome sequences ranging from flying insects to human. These sequences are characterized by high levels of sequence conservation, ranging from 66% to 100% s... | ['Amino Acid Motifs', 'Amino Acid Sequence', 'Animals', 'DNA-Binding Proteins', 'Diptera', 'Electrophoretic Mobility Shift Assay', 'Evolution, Molecular', 'Gene Duplication', 'Genomics', 'Humans', 'Invertebrates', 'Kruppel-Like Transcription Factors', 'Mammals', 'Molecular Sequence Data', 'Retroelements', 'Sequence Hom... | 17,478,514 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D12.776.260'], ['B01.050.500.131.617.720.500.500.750'], ['E05.196.401.500'], ['G05.045.250', 'G16.075.250'], ['G05.365.590.320', 'G05.558.320'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['B... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
[Teaching of microsurgery--in service of research and clinical practice]. | We analyse the improving role of teaching microsurgery, the advantages of the microsurgical models in research and clinical practice. We summarize our experience in teaching basic microsurgery according to Furka's model in the last 15 years. The main characteristics of the principles are: activity, synchronism, video a... | ['Biomedical Research', 'Clinical Medicine', 'Curriculum', 'Education, Medical', 'Education, Medical, Graduate', 'Humans', 'Hungary', 'Microsurgery'] | 16,018,278 | [['H01.770.644.145'], ['H02.403.200'], ['I02.158'], ['I02.358.399'], ['I02.358.337.350', 'I02.358.399.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.248.495'], ['E04.494', 'E05.591.580']] | ['Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 |
Lipid analysis for the identification of mycobacteria: an appraisal. | A review is presented of the use of lipid analysis by thin-layer chromatography for the identification and classification of mycobacteria. Specific lipid patterns are known for 15 species (in some cases a species may exhibit more than one pattern), and these patterns normally correlate well with serotypes. In six speci... | ['Chromatography, Thin Layer', 'Lipids', 'Mycobacterium'] | 7,339,816 | [['E05.196.181.400.537'], ['D10'], ['B03.510.024.962.500', 'B03.510.460.400.410.552.552']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rearrangement and possible amplification of the ribosomal RNA gene sites in the human chronic myelogenous leukemia cell line K562. | We have studied the location of the nucleolar organizer regions (NORs) in the human chronic myeloid leukemia cell line K562. In man, the NORs are normally found on the short arms of the acrocentric chromosomes. We show that in the K562 line, the NORs are substantially rearranged with both insertional and terminal NORs.... | ['Cell Line', 'Chromosome Mapping', 'Chromosomes, Human, 13-15', 'Chromosomes, Human, 16-18', 'Gene Amplification', 'Genetic Markers', 'Humans', 'Karyotyping', 'Leukemia, Myeloid', 'Nucleolus Organizer Region', 'RNA, Ribosomal', 'Translocation, Genetic'] | 3,861,234 | [['A11.251.210'], ['E05.393.183'], ['A11.284.187.520.300.370', 'G05.360.162.520.300.370'], ['A11.284.187.520.300.415', 'G05.360.162.520.300.415'], ['G05.308.250', 'G05.365.590.310', 'G05.558.315'], ['D23.101.387', 'G05.695.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.385.315', 'E05.200.500.... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lithium treatment and blood pressure. | The average systolic and diastolic blood pressures of 377 manic-depressive patients were not significantly different before and during lithium treatment. Before the treatment blood pressure was slightly but significantly lower in spring and fall than in winter and summer; during lithium treatment the seasonal variation... | ['Adult', 'Bipolar Disorder', 'Blood Pressure', 'Diastole', 'Female', 'Humans', 'Lithium', 'Male', 'Middle Aged', 'Seasons', 'Systole'] | 3,703,926 | [['M01.060.116'], ['F03.084.500'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G09.330.580.295', 'G11.427.494.554.250', 'G11.427.494.570.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.549.450', 'D01.268.557.290', 'D01.552.528.480', 'D01.552.547.290'], ['M01.060.116.630'], ['G01.910.645.661', 'G16.5... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Efficacy and Safety of Hyperbaric Oxygen Therapy Used in Patients With Diabetic Foot: A Meta-analysis of Randomized Clinical Trials. | PURPOSE: The efficacy and safety profile of hyperbaric oxygen therapy (HBOT) in patients with diabetic foot ulcer have been controversial in recent years. Our meta-analysis was undertaken to evaluate the efficacy and safety profile of HBOT in patients with diabetic foot ulcer.METHODS: We searched the PubMed, Cochrane L... | ['Diabetic Foot', 'Humans', 'Hyperbaric Oxygenation', 'Randomized Controlled Trials as Topic', 'Treatment Outcome'] | 28,935,291 | [['C14.907.320.191', 'C17.800.893.592.450.200', 'C19.246.099.500.191', 'C19.246.099.937.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.880.690.490'], ['E05.318.372.250.250.365.500', 'N05.715.360.330.250.250.365.500', 'N06.850.520.450.250.250.365.500'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Fatal infection with echovirus 11. | Twenty-four fatal cases of echo 11 infection in the eleven years 1968-78 are presented. All were children, and could be divided into two groups according to age at death and clinical presentation. The first group comprised 12 babies who died aged between 5 and 11 days after a short illness characterised by collapse, ac... | ['Adrenal Glands', 'Antibodies, Viral', 'Child, Preschool', 'Echovirus Infections', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Kidney Medulla', 'Male', 'Maternal-Fetal Exchange', 'Pregnancy', 'United Kingdom'] | 7,199,896 | [['A06.300.071'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['M01.060.406.448'], ['C01.925.782.687.359.347'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['A05.810.453.466'], ['G08.686.784.769.455'], ['G08.686.784.769'], ['Z... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
NHLBI issues update on task force report on high blood pressure in children and adolescents. | Health-related behaviors that reduce the risk of cardiovascular disease should be encouraged for all children and their families. Physicians should monitor blood pressure, counsel patients about appropriate nutrition and exercise, and emphasize the importance of not smoking. Because black adults in the United States ha... | ['Adolescent', 'Body Height', 'Child', 'Child Welfare', 'Child, Preschool', 'Female', 'Humans', 'Hypertension', 'Infant', 'Male', 'National Institutes of Health (U.S.)', 'Risk Factors', 'United States'] | 9,149,655 | [['M01.060.057'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['M01.060.406'], ['I01.880.787.293'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.703'], ['I01.409.418.750.600.650.496', 'N03.540.052.750', 'N03.54... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Evaluation of the lacrimal recess of the maxillary sinus: an anatomical study. | UNLABELLED: The anatomical relation between the maxillary sinus and the nasolacrimal duct has gained greater importance with the advent of microsurgeries and endoscopic-assisted sinonasal procedures, and the growing use of endonasal surgery to perform middle meatus procedures and transnasal dacryocystorhinostomy. We di... | ['Cadaver', 'Humans', 'Lacrimal Apparatus', 'Maxillary Sinus'] | 23,503,905 | [['C23.550.260.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.463', 'A10.336.422'], ['A04.531.621.578']] | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An investigation of the bending stiffness of and the plane stresses generated by a flanged external fixator pin. | In an attempt to reduce pin loosening, a flanged external fixator pin has been designed and its bending stiffness has been compared with that of a standard pin. The pins were inserted into pilot holes previously drilled into a piece of teak hardwood. Loads of different magnitudes were applied at a fixed moment arm and ... | ['Biomechanical Phenomena', 'Bone Nails', 'External Fixators', 'Models, Theoretical', 'Stress, Mechanical'] | 7,714,660 | [['G01.154.090', 'G01.374.089'], ['E07.695.370.249', 'E07.858.442.660.460.249', 'E07.858.690.725.460.249'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ['E05.599'], ['G01.374.835']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Colon cancer. Study of 153 cases and comparison with a series of 140 historic cases]. | The authors study the epidemiological, diagnostic and therapeutic features of 153 consecutive cases of colon cancers collected between 1985 and 1998. They compare the results with those of a previous study performed in the same hospital service (140 cases between 1966 and 1984). It is a series of 79 men and 74 women (s... | ['Adult', 'Aged', 'Chemotherapy, Adjuvant', 'Colonic Neoplasms', 'Diagnosis, Differential', 'Female', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Prognosis', 'Retrospective Studies', 'Survival Analysis'] | 10,730,153 | [['M01.060.116'], ['M01.060.116.100'], ['E02.186.170', 'E02.319.170'], ['C04.588.274.476.411.307.180', 'C06.301.371.411.307.180', 'C06.405.249.411.307.180', 'C06.405.469.158.356.180', 'C06.405.469.491.307.180'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Solitary Cerebral Metastases vs | BACKGROUND/AIM: The differentiation between cerebral metastases (CM) and high-grade gliomas (HGG) can be difficult on magnetic resonance imaging (MRI). The aim of this study was to evaluate the usefulness of searching two MRI signs (signal alteration in the adjacent cortex, SAAC, and peripheral rim sign, PRS), in order... | ['Adult', 'Aged', 'Aged, 80 and over', 'Brain Neoplasms', 'Cerebral Cortex', 'Diagnosis, Differential', 'Female', 'Glioma', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neoplasm Grading', 'ROC Curve', 'Radiographic Image Enhancement', 'Reproducibility of Results'] | 31,519,594 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['A08.186.211.200.885.287.500'], ['E01.171'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.5... | ['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
[Cerebral air embolism after central venous catheter]. | Introduction of air into the arterial circulation can cause cerebral air embolism, leading to severe neurological deficits. A case is reported on a patient suffering from fatal cerebral air embolism after a subclavian vein catheter had been inserted. The risks associated with inserting and removing central venous cathe... | ['Aged', 'Catheterization, Central Venous', 'Catheters, Indwelling', 'Embolism, Air', 'Fatal Outcome', 'Humans', 'Intracranial Embolism and Thrombosis', 'Male', 'Radiography', 'Risk Factors', 'Subclavian Vein'] | 9,340,034 | [['M01.060.116.100'], ['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['E07.132.500'], ['C14.907.355.350.254'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.400.975.550.325', 'N06.850.520.308.985.550.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Endovascular recanalisation of subclavian artery stenotic-occlusive lesions]. | Recently, percutaneous transluminal angioplasty (PTA) with stent placement has gained greater acceptance for the treatment of hemodynamically significant atherosclerotic lesions involving the brachiocephalic, subclavian and vertebral vessels. PTA is performed instead of extratoracic bypass surgery, which is associated ... | ['Angiography', 'Angioplasty, Balloon', 'Arterial Occlusive Diseases', 'Female', 'Humans', 'Male', 'Middle Aged', 'Subclavian Artery', 'Subclavian Steal Syndrome', 'Treatment Outcome', 'Ultrasonography, Doppler'] | 18,985,898 | [['E01.370.350.700.060', 'E01.370.370.050'], ['E02.148.050.060', 'E04.100.814.529.124.060', 'E04.502.382.124.060', 'E05.157.016.060'], ['C14.907.137'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07.015.114.839'], ['C10.228.140.300.150.956.700', 'C14.907.253.092.956.700'], ['E01.789.800', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Pharmacological comparative study on baiqian and baiwei]. | The decoction of Cynanchum glaucescens and the ethanol extract of C. stauntonii show significant antitussive and expectorant actions. The decoctions of C. stauntonii or C. glaucescens have antiasthmatic and anti-inflammatory effects. The decoction of C. atratum has some expectorant effect but no antitussive or antiasth... | ['Adolescent', 'Animals', 'Antitussive Agents', 'Drugs, Chinese Herbal', 'Expectorants', 'Female', 'Guinea Pigs', 'Humans', 'Magnoliopsida', 'Male', 'Mice'] | 9,772,633 | [['M01.060.057'], ['B01.050'], ['D27.505.954.427.153', 'D27.505.954.796.090'], ['D20.215.784.500.350', 'D26.335'], ['D27.505.954.796.250'], ['B01.050.150.900.649.313.992.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.650.940.800.575.912.250'], ['B01.050.150.900.649.313.992.635.505.500']] | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Progress in the treatment of esophageal and cardial carcinomas (author's transl)]. | Progress has been made in the treatment of esophageal and cardial carcinomas in three areas: (1) a special type of esophageal cancer -- the adeno-carcinoma in the columnar lines lower esophagus -- gained more clinical relevance. In the absence of other therapeutical possibilities this type of esophageal cancer is of gr... | ['Adenocarcinoma', 'Cardia', 'Esophageal Neoplasms', 'Humans', 'Neoplasm Staging', 'Precancerous Conditions', 'Stomach Neoplasms'] | 7,339,386 | [['C04.557.470.200.025'], ['A03.556.875.875.163'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.789.625'], ['C04.834'], ['C04.588.274.476.767', 'C06.301.371.767', 'C06.405.249.767', 'C06.405.748.789']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distributional changes of osteoclasts and pre-osteoclastic cells in periodontal tissues during experimental tooth movement as revealed by quantitative immunohistochemistry of H(+)-ATPase. | To investigate the mechanism of alveolar bone remodeling in response to orthodontic force application, we examined the distribution of osteoclasts and pre-osteoclastic cells using quantitative immunohistochemistry of vacuolar type H(+)-ATPase. For orthodontic force to be produced by the Waldo method, an orthodontic ela... | ['Alveolar Bone Loss', 'Alveolar Process', 'Animals', 'Bone Remodeling', 'Dental Stress Analysis', 'Immunohistochemistry', 'Male', 'Osteoclasts', 'Periodontal Ligament', 'Proton-Translocating ATPases', 'Rats', 'Rats, Wistar', 'Tooth Movement Techniques'] | 9,042,081 | [['C05.116.264.150', 'C07.465.714.354.500'], ['A02.835.232.781.324.502.125', 'A14.521.125', 'A14.549.167.646.094'], ['B01.050'], ['G11.427.213', 'G16.762.150'], ['E06.308'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H0... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
[Carotid dissection during angioplasty for vasospasm induced by subarachnoid haemorrhage. The use of multimodal cerebral monitoring]. | We report the case of a 54-year-old woman presenting subarachnoid haemorrhage. She experienced multiple vasospasms and treatment included triple-H (hypervolaemia, hypertension, and haemodilution) and endovascular therapies. Right internal carotid dissection complicated angioplasty of the right middle cerebral artery. C... | ['Angioplasty', 'Carotid Artery, Internal, Dissection', 'Female', 'Humans', 'Middle Aged', 'Subarachnoid Hemorrhage', 'Vasospasm, Intracranial'] | 19,945,247 | [['E02.148.050', 'E04.100.814.529.124', 'E04.502.382.124', 'E05.157.016'], ['C10.228.140.300.200.345.300', 'C10.228.140.300.350.500.300', 'C10.900.250.300.300', 'C14.907.055.050.150', 'C14.907.253.123.345.300', 'C14.907.253.535.500.300', 'C26.915.200.200.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Histological evaluation of biodegradable and non-degradable membranes placed transcutaneously in rats. | The aim of this study was to assess histologically the response to membrane materials that might be used for guided tissue regeneration procedures, using a transcutaneous model on the dorsal surface of the rat. The materials included expanded polytetrafluoroethylene (PTFE) membrane (Gore-Tex), PTFE Millipore filter, bi... | ['Absorption', 'Animals', 'Biocompatible Materials', 'Cell Division', 'Connective Tissue', 'Epithelium', 'Granulation Tissue', 'Lactates', 'Lactic Acid', 'Male', 'Materials Testing', 'Membranes, Artificial', 'Micropore Filters', 'Monocytes', 'Neutrophils', 'Polyesters', 'Polymers', 'Polytetrafluoroethylene', 'Rats', 'R... | 1,795,054 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A10.165'], ['A10.272'], ['A10.165.450'], ['D02.241.511.459'], ['D02.241.511.459.450'], ['E05.570'], ['D25.479'... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Decorrelating Kinetic and Relaxation Parameters in Exchange Saturation Transfer NMR: A Case Study of N-Terminal Huntingtin Peptides Binding to Unilamellar Lipid Vesicles. | Dark state exchange saturation transfer (DEST) and lifetime line-broadening (Ä R2, the difference in the measured transverse relaxation rates for the observable species in the presence and absence of exchange with a species characterized by very large intrinsic transverse relaxation rates) have proven to be powerful NM... | ['Cholesterol', 'Escherichia coli', 'Exons', 'Huntingtin Protein', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Peptide Fragments', 'Peptides', 'Phosphatidylcholines', 'Phosphatidylglycerols', 'Protein Binding', 'Protein Conformation, alpha-Helical', 'Unilamellar Liposomes'] | 30,156,416 | [['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.137.232'], ['D12.776.441'], ['G01.374.661', 'G02.111.490'], ['E05.196.867.519'], ['D12.644.541'], ['D12.644'], ['D10.570.755.375.760.400.800'], ['D10.570.755.375.760.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The perceptions of people with multiple sclerosis about the NHS provision of physiotherapy services. | PURPOSE: In 2008, the Royal College of Physicians (RCP) and MS Trust conducted a second audit of NHS services for people with MS (PwMS). Using the free text comments obtained from the RCP and MS Trust audit, this study aimed to perform content analysis on the views of PwMS about MS services, focussing on physiotherapy ... | ['Adult', 'Aged', 'Female', 'Humans', 'Information Management', 'Male', 'Medical Audit', 'Middle Aged', 'Multiple Sclerosis', 'Needs Assessment', 'Patient Satisfaction', 'Physical Therapy Modalities', 'Social Perception', 'State Medicine', 'United Kingdom', 'Waiting Lists'] | 23,651,127 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.399'], ['N04.761.700.250.500', 'N05.700.175.500'], ['M01.060.116.630'], ['C10.114.375.500', 'C10.314.350.500', 'C20.111.258.250.500'], ['I02.594', 'N03.349.380.565', 'N05.300.537'], ['F01.100.150.750.625', 'F01.145.488.887.625... | ['Named Groups [M]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
The role of call frequency and the auditory papillae in phonotactic behavior in male Dart-poison frogs Epipedobates femoralis (Dendrobatidae). | Territorial males of the pan-Amazonian Dart-poison frog, Epipedobates femoralis, are known to present stereotypic phonotactic responses to the playback of conspecific and synthetic calls. Fixed site attachment and a long calling period within an environment of little temperature change render this terrestrial and diurn... | ['Acoustic Stimulation', 'Animal Communication', 'Animals', 'Ear, Inner', 'Male', 'Neurons, Afferent', 'Ranidae', 'Stereotyped Behavior', 'Vocalization, Animal'] | 15,278,399 | [['E02.037', 'E02.190.888.030', 'E05.723.136'], ['F01.145.113.055'], ['B01.050'], ['A09.246.300'], ['A08.675.650', 'A11.671.650'], ['B01.050.150.900.090.180.708'], ['F01.145.896'], ['F01.145.113.055.800']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Incidence of abdominal hernias in service members, active component, U.S. Armed Forces, 2005-2014. | From 1 January 2005 through 31 December 2014, a total of 87,480 incident diagnoses of the five types of abdominal hernia (incidence rate 63.3 cases per 10,000 person-years) were documented in the health records of 72,404 active component service members. The overall incidence rate of inguinal hernias among males was si... | ['Adult', 'Age Distribution', 'Female', 'Hernia, Abdominal', 'Hernia, Inguinal', 'Hernia, Umbilical', 'Herniorrhaphy', 'Humans', 'Incidence', 'Male', 'Middle Aged', 'Military Personnel', 'Sex Distribution', 'United States', 'Young Adult'] | 27,602,797 | [['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['C23.300.707.374'], ['C23.300.707.374.875'], ['C16.614.378', 'C23.300.707.374.937.500'], ['E04.680.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Synthesis, anticancer, structural, and computational docking studies of 3-benzylchroman-4-one derivatives. | A series of 3-Benzylchroman-4-ones were synthesized and screened for anticancer activity by MTT assay. The compounds were evaluated against two cancerous cell lines BT549 (human breast carcinoma), HeLa (human cervical carcinoma), and one noncancerous cell line vero (normal kidney epithelial cells). 3b was found to be t... | ['Animals', 'Antineoplastic Agents', 'Cell Line, Tumor', 'Cell Proliferation', 'Chlorocebus aethiops', 'Crystallography, X-Ray', 'Dose-Response Relationship, Drug', 'Humans', 'Molecular Docking Simulation', 'Molecular Structure', 'Structure-Activity Relationship', 'Vero Cells'] | 29,074,256 | [['B01.050'], ['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['B01.050.150.900.649.313.988.400.112.199.120.126.110'], ['E05.196.309.742.225'], ['G07.690.773.875', 'G07.690.936.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595.249', 'L01.224.160.2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Prevalence and time trend analysis of antimicrobial resistance in respiratory bacterial pathogens collected from diseased pigs in USA between 2006-2016. | Swine respiratory disease complex (SRDC) causes massive economic losses to the swine industry and is a major animal welfare concern. Antimicrobials are mainstay in treatment and control of SRDC. However, there is a lack of data on the prevalence and trends in resistance to antimicrobials in bacterial pathogens associat... | ['Animals', 'Anti-Bacterial Agents', 'Bacteria', 'Drug Resistance, Bacterial', 'Prevalence', 'Respiratory Tract Diseases', 'Swine', 'Swine Diseases', 'United States'] | 31,785,428 | [['B01.050'], ['D27.505.954.122.085'], ['B03'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'], ['C08'], ['B01.050.150.900.649.313.500.880'], ['C22.905'], ['Z01.107.567.875']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Identification and characterization of a new organic hydroperoxide resistance (ohr) gene with a novel pattern of oxidative stress regulation from Xanthomonas campestris pv. phaseoli. | We have isolated a new organic hydroperoxide resistance (ohr) gene from Xanthomonas campestris pv. phaseoli. This was done by complementation of an Escherichia coli alkyl hydroperoxide reductase mutant with an organic hydroperoxide-hypersensitive phenotype. ohr encodes a 14.5-kDa protein. Its amino acid sequence shows ... | ['Amino Acid Sequence', 'Bacterial Proteins', 'Base Sequence', 'Gene Expression Regulation, Bacterial', 'Genes, Bacterial', 'Genes, Regulator', 'Genetic Complementation Test', 'Molecular Sequence Data', 'Mutation', 'Oxidative Stress', 'Sequence Alignment', 'Sequence Homology, Amino Acid', 'Xanthomonas campestris'] | 9,573,147 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.308.300'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G05.360.340.024.340.425'], ['E05.393.281.526'], ['L01.453.245.667'], ['G05.365.590'], ['G03.6... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Examination of fine-scale spatial-temporal overlap and segregation between two closely related congeners Gadus morhua and Gadus ogac in coastal Newfoundland. | The spatial and temporal movement patterns of sympatric juvenile Atlantic cod Gadus morhua and Greenland cod Gadus ogac were studied using high-resolution radio-acoustic positioning in a coastal area of Newfoundland during the summers of 2009 and 2010. A total of 20 fish (10 G. ogac and 10 G. morhua) were equipped with... | ['Acoustics', 'Animal Identification Systems', 'Animals', 'Gadiformes', 'Gadus morhua', 'Homing Behavior', 'Newfoundland and Labrador', 'Periodicity', 'Seasons', 'Spatio-Temporal Analysis'] | 25,041,096 | [['H01.671.031'], ['E05.035'], ['B01.050'], ['B01.050.150.900.493.467'], ['B01.050.150.900.493.467.400'], ['F01.145.113.646'], ['Z01.107.567.176.540'], ['G01.910.645', 'G07.180.562'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['E05.318.740.933.500', 'N05.715.360.750.746.500', 'N06.850.520.8... | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Primary structure of a gamma subunit of G protein, gamma 12, and its phosphorylation by protein kinase C. | We have determined the primary structure of a novel gamma subunit (gamma 12, previously designated gamma S1) of G protein purified from bovine spleen. The mature gamma 12 protein composed of 68 amino acids had acetylated serine at the N terminus and geranylgeranylated/carboxylmethylated cysteine at the C terminus. This... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Calcium', 'Cattle', 'Cells, Cultured', 'GTP-Binding Proteins', 'Molecular Sequence Data', 'Phosphorylation', 'Protein Kinase C', 'Tetradecanoylphorbol Acetate'] | 7,493,986 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['B01.050.150.900.649.313.500.380.271'], ['A11.251'], ['D08.811.277.040.330.300', 'D12.776.157.325'], ['L01.453.245.667'], ['G02.111.665', 'G02.607.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
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