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The effect of protein degradation on cellular growth characteristics. | The role of protein degradation in cellular proliferation was investigated by measurements of the rates of degradation of labile and stable proteins for a number of cell types under various growth conditions. The rate of protein degradation was found to be a relatively invariant parameter in that it did not change afte... | ['Cell Division', 'Cell Line', 'Cell Transformation, Neoplastic', 'Cell Transformation, Viral', 'Cycloheximide', 'DNA', 'Histidinol', 'Interphase', 'Kinetics', 'Proteins'] | 670,299 | [['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['C04.697.098.500', 'C23.550.727.098.500'], ['C04.697.098.500.160', 'C23.550.727.098.500.160', 'G06.920.143'], ['D03.383.621.808.240'], ['D13.444.308'], ['D02.033.100.624.380', 'D02.033.755.624.380', 'D02.092.063.624.380', 'D03.... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Radionuclide evaluation of circulatory shunts. | With first-pass radionuclide angiography, it is possible to visualize sequentially the cardiovascular structures and to obtain computer-generated time-activity curves for regions of interest over these structures. Analysis of these curves permits the detection, localization, and quantitation of intracardiac shunts and ... | ['Ductus Arteriosus, Patent', 'Electrocardiography', 'Heart Defects, Congenital', 'Heart Septal Defects, Atrial', 'Heart Septal Defects, Ventricular', 'Hemodynamics', 'Humans', 'Infant', 'Infant, Newborn', 'Models, Cardiovascular', 'Postoperative Complications', 'Radionuclide Imaging', 'Sodium Pertechnetate Tc 99m', 'T... | 6,100,478 | [['C14.240.400.340', 'C14.280.400.340', 'C16.131.240.400.340'], ['E01.370.370.380.240', 'E01.370.405.240'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['C14.240.400.560.375', 'C14.280.400.560.375', 'C16.131.240.400.560.375'], ['C14.240.400.560.540', 'C14.280.400.560.540', 'C16.131.240.400.560.540'], ['G09.330.3... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Suppressor cells in specific unresponsiveness to skin allografts in ALS-treated, marrow-injected mice. | Lymphoid cells from ALS-treated (C57BL/6 x A/J)F1 (B6AF1) mice bearing enhanced C3H/He grafts were assayed for their ability to suppress the response to C3H/He grafts after transfer to syngeneic B6AF1 recipients. Cells were transferred from ALS-treated B6AF1 mice that had received either a C3H/He graft alone, C3H/He ma... | ['Animals', 'Antilymphocyte Serum', 'Bone Marrow', 'Bone Marrow Transplantation', 'Graft Survival', 'Immunologic Memory', 'Lymph Nodes', 'Mice', 'Mice, Inbred A', 'Mice, Inbred C3H', 'Mice, Inbred C57BL', 'Mice, Inbred DBA', 'Skin Transplantation', 'Spleen', 'T-Lymphocytes, Regulatory', 'Thymus Gland', 'Transplantation... | 6,444,769 | [['B01.050'], ['A12.207.152.846.500.203', 'D12.776.124.486.485.114.573.203', 'D12.776.124.790.651.114.573.203', 'D12.776.377.715.548.114.573.203', 'D20.215.401.203'], ['A15.382.216'], ['E02.095.147.725.040', 'E04.936.580.040'], ['G12.875.545.340'], ['G12.450.050.500'], ['A10.549.400', 'A15.382.520.604.412'], ['B01.050.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Can Pathogenic and Nonpathogenic Bacteria Be Distinguished by Sensory Protein Abundance? | Signal transduction systems are essential for microorganisms to respond to their ever-changing environment. They can be distinguished into one-component systems, two-component systems, and extracytoplasmic-function ó factors. Abundances of a few signal-transducing proteins, termed herein as sensory proteins (SPs), have... | ['Escherichia coli', 'Escherichia coli Proteins', 'Genome, Bacterial', 'Virulence'] | 32,385,079 | [['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['G05.360.340.358.207'], ['G06.930']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of emulsions of carbon perfluoride compounds on the blood plasma complement system and functional state of the rabbit brain]. | Experiments were conducted in vitro on rabbits to study the effect of emulsions based on composition of carbon perfluorides (decalin perfluoride/methyl cyclohexyl piperidine perfluoride) and proxanol (P-268) on the blood complement system. It is shown that despite preservation of the composition some emulsions activate... | ['Animals', 'Brain', 'Complement System Proteins', 'Emulsions', 'Fluorocarbons', 'Humans', 'In Vitro Techniques', 'Piperidines', 'Rabbits'] | 1,818,279 | [['B01.050'], ['A08.186.211'], ['D12.776.124.486.274'], ['D20.280.260', 'D26.255.165.260'], ['D02.455.526.510.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['D03.383.621'], ['B01.050.150.900.649.313.968.700']] | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Alcohol-related cues reduce cognitive control in social drinkers. | Alcohol-related stimuli attract social drinkers' attention (attentional bias). We devised a dual task to test whether attentional biases to alcohol-related stimuli are modulated by cognitive control mechanisms. Sixteen nondependent healthy social drinkers were required to respond to the direction of a central arrow (ta... | ['Adolescent', 'Adult', 'Alcohol Drinking', 'Attention', 'Cognition Disorders', 'Cues', 'Female', 'Humans', 'Male', 'Reaction Time', 'Reward', 'Severity of Illness Index', 'Social Behavior', 'Social Behavior Disorders', 'Surveys and Questionnaires', 'United Kingdom', 'Young Adult'] | 23,238,087 | [['M01.060.057'], ['M01.060.116'], ['F01.145.317.269'], ['F02.830.104.214'], ['F03.615.250'], ['F02.463.425.234'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['F02.463.425.770.836'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Positive predictive value of screening mammography by age and family history of breast cancer. | OBJECTIVE: To determine the positive predictive value (PPV) of low-cost screening mammography according to age and family history of breast cancer.DESIGN: Cross-sectional.SETTING: Six counties in northern California.PARTICIPANTS: A total of 31,814 women aged 30 years and older referred for mammography to the University... | ['Adult', 'Age Factors', 'Aged', 'Breast Neoplasms', 'Cross-Sectional Studies', 'Female', 'Humans', 'Mammography', 'Mass Screening', 'Medical History Taking', 'Middle Aged', 'Neoplasm Staging', 'Predictive Value of Tests', 'San Francisco'] | 8,230,621 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700.500'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Susceptibility of Culex sitiens to Japanese encephalitis virus in peninsular Malaysia. | The susceptibility of Culex sitiens to Japanese Encephalitis (JE) virus was examined in the laboratory. Cx. sitiens became infected with JE virus on day 8 and subsequently it is able to transmit the virus when it takes a blood meal. Both parts of the experiment were carried out using artificial membrane feeding techniq... | ['Animals', 'Culex', 'Disease Susceptibility', 'Encephalitis Virus, Japanese', 'Malaysia', 'Reverse Transcriptase Polymerase Chain Reaction'] | 12,031,077 | [['B01.050'], ['B01.050.500.131.617.720.500.500.750.712.500.875.225'], ['C23.550.291.687', 'G07.100.250'], ['B04.820.230.475.227', 'B04.820.578.344.350.300.227'], ['Z01.252.145.487'], ['E05.393.620.500.725']] | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Optimized phase gradient measurements and phase-amplitude interplay in optical coherence elastography. | In compressional optical coherence elastography, phase-variation gradients are used for estimating quasistatic strains created in tissue. Using reference and deformed optical coherence tomography (OCT) scans, one typically compares phases from pixels with the same coordinates in both scans. Usually, this limits the all... | ['Elasticity Imaging Techniques', 'Humans', 'Image Processing, Computer-Assisted', 'Models, Biological', 'Phantoms, Imaging', 'Tomography, Optical Coherence'] | 27,824,215 | [['E01.370.350.850.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E05.599.395'], ['E07.671'], ['E01.370.350.589.249.500', 'E01.370.350.825.805.500', 'E05.642.249.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Evidence for existence of type A MAO in mitochondria from human placenta (author's transl)]. | The existence of type A and B MAO in mitochondria from human placenta was investigated on the basis of inhibitions by selective MAO inhibitors, such as clorgyline (type A inhibitor) and pargyline and deprenyl (type B inhibitors) with serotonin (substrate for type A MAO), tyramine (substrate for both types of MAO) and b... | ['Animals', 'Female', 'Humans', 'Male', 'Methods', 'Mitochondria', 'Mitochondria, Liver', 'Monoamine Oxidase', 'Monoamine Oxidase Inhibitors', 'Placenta', 'Pregnancy', 'Rats', 'Subcellular Fractions', 'Substrate Specificity', 'Time Factors', 'Trypsin'] | 711,033 | [['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.581'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['A11.284.430.214.190.875.564.461', 'A11.284.835.626.461'], ['D08.811.682.664.750'], ['D27.505.519.389.616'], ['A16.710'], ['G08.686.784.769'], ['B01.050.150.900.649.313.992.635.505.700'], ['A... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Superior performance of continuous over pulsatile flow ventricular assist devices in the single ventricle circulation: A computational study. | This study compares the physiological responses of systemic-to-pulmonary shunted single ventricle patients to pulsatile and continuous flow ventricular assist devices (VADs). Performance differences between pulsatile and continuous flow VADs have been clinically observed, but the underlying mechanism remains poorly und... | ['Cardiac Output', 'Heart-Assist Devices', 'Hemorheology', 'Humans', 'Ventricular Function'] | 28,038,771 | [['E01.370.370.380.150', 'G09.330.380.124'], ['E04.050.430', 'E07.695.300.300', 'E07.858.082.374.300'], ['E05.830.250', 'G09.188.370', 'G09.330.380.630'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.330.955']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cessation of gonadotropin-releasing hormone analogue (GnRH-a) upon down-regulation versus conventional long GnRH-a protocol in poor responders undergoing in vitro fertilization. | OBJECTIVE: To determine whether a controlled ovarian hyperstimulation (COH) regimen that involves GnRH agonist (GnRH-a) discontinuation before administration of gonadotropins would benefit poor responders.DESIGN: A prospective, randomized controlled trial.SETTING: Hospital-based IVF Unit.PATIENT(S): Sixty-three patient... | ['Adult', 'Buserelin', 'Embryo Transfer', 'Estradiol', 'Female', 'Fertilization in Vitro', 'Follicle Stimulating Hormone', 'Humans', 'Male', 'Ovulation Induction', 'Pregnancy', 'Prospective Studies', 'Triptorelin Pamoate'] | 10,519,608 | [['M01.060.116'], ['D06.472.699.327.740.320.100', 'D12.644.400.400.740.320.100', 'D12.644.456.460.150', 'D12.644.548.365.740.320.100', 'D12.776.631.650.405.740.320.100'], ['E02.875.800.500', 'E05.820.800.500'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['E02.875.800.750', 'E05.820.800.750'], ['D06.472.699... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Neurofibromatosis associated with a coronary artery aneurysm. | A case of a patient with type 1 neurofibromatosis associated with popliteal and coronary artery aneurysms is described in which cross-sectional imaging provided diagnostic information. | ['Aged', 'Coronary Aneurysm', 'Humans', 'Male', 'Neurofibromatosis 1', 'Tomography, X-Ray Computed'] | 11,144,803 | [['M01.060.116.100'], ['C14.280.647.250.250', 'C14.907.055.395', 'C14.907.585.250.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.580.600.580.590.650', 'C04.700.631.650', 'C10.562.600.500', 'C10.574.500.549.400', 'C10.668.829.675', 'C16.320.400.560.400', 'C16.320.700.633.650'], ['E01.370.350.350.810',... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Electron microscopic findings of the peripheral nerve lesions of nude mice inoculated with M. leprae. | Peripheral nerve lesions of nude mice inoculated with Mycobacterium leprae were examined from 1 year to 1 year and 8 months post-inoculation. Leprosy bacilli and intracytoplasmic foamy structures were found in the perineurial cells, endothelial cells of capillaries, Schwann cells, and axons of the myelinated nerve fibe... | ['Animals', 'Endothelium', 'Leprosy', 'Mice', 'Mice, Nude', 'Microscopy, Electron', 'Mycobacterium leprae', 'Nerve Fibers, Myelinated', 'Peripheral Nerves', 'Schwann Cells'] | 3,889,194 | [['B01.050'], ['A10.272.491'], ['C01.150.252.410.040.552.475.371'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.500'], ['E01.370.350.515.402', 'E05.595.402'], ['B03.510.024.962.500.502', 'B03.510.460.400.410.552.552.502'], ['A08.675.542.512', 'A11.671.501.512', 'A11.671.51... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Low prevalence of the intrinsic form of atopic dermatitis among adult patients. | BACKGROUND: Atopic dermatitis (AD) is a chronic inflammatory skin disease commonly associated with respiratory allergies such as rhinitis and asthma, and a high serum level of IgE. In contrast to the 'classic' IgE-mediated allergic (extrinsic) form of AD, approximately 20% of the patients are reported to show normal Ig... | ['Adult', 'Age of Onset', 'Aged', 'Dermatitis, Atopic', 'Female', 'Follow-Up Studies', 'Humans', 'Immunoglobulin E', 'Male', 'Middle Aged', 'Prevalence', 'Severity of Illness Index', 'Sex Distribution'] | 16,629,795 | [['M01.060.116'], ['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.116.100'], ['C16.320.850.210', 'C17.800.174.193', 'C17.800.815.193', 'C17.800.827.210', 'C20.543.480.343'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400... | ['Named Groups [M]', 'Health Care [N]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Transforming growth factor-beta1 and regulators of apoptosis. | Growth inhibitory function of transforming growth factor-beta1 (TGF-beta1) is abolished in colorectal cancer cells as a consequence of mutations of various downstream signaling agents, such as p53, which fail to respond to TGF-beta1 stimulation. TGF-beta1 could also suppress T-cell-mediated anticancer immunity. We aime... | ['Apoptosis', 'Colon', 'Colorectal Neoplasms', 'Cytoplasm', 'Female', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Rectum', 'Transforming Growth Factor beta1', 'Tumor Suppressor Protein p53', 'bcl-2-Associated X Protein', 'bcl-X Protein'] | 19,723,045 | [['G04.146.954.035'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['A11.284.430.214'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370... | ['Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Named Groups [M]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Dairy washwater treatment using a horizontal flow biofilm system. | In Ireland, land-spreading is the most widely used method for treating dairy wastewaters. This can be labour intensive and can cause, in some cases, nitrate contamination of groundwater. In this study a simple pilot-scale horizontal flow biofilm reactor (HFBR) with a step-feed was developed and tested at a dairy farm s... | ['Biofilms', 'Carbon', 'Dairying', 'Industrial Waste', 'Ireland', 'Nitrogen', 'Oxygen', 'Water Pollutants'] | 19,029,732 | [['A20.593', 'G06.120'], ['D01.268.150'], ['J01.040.246'], ['D20.944.420', 'N06.850.460.710.420'], ['Z01.542.467', 'Z01.639.587'], ['D01.268.604', 'D01.362.625'], ['D01.268.185.550', 'D01.362.670'], ['D27.888.284.903']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Geographicals [Z]'] | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Associative learning of Nasonia vitripennis Walker (Hymenoptera:Pteromalidae) to methyldisulfanylmethane. | Traditional methods of volatile detection used by police typically consist of reliance on canine olfaction. However, dogs have some limitations such as cost of training and time of conditioning. The possibility of using parasitic wasps for detecting explosives and narcotics has been developed. Moreover, wasps are cheap... | ['Animals', 'Conditioning, Classical', 'Female', 'Forensic Sciences', 'Odorants', 'Volatile Organic Compounds', 'Wasps'] | 24,313,637 | [['B01.050'], ['F02.463.425.179.308'], ['I01.198.780'], ['G16.500.275.640', 'N06.230.480'], ['D02.974'], ['B01.050.500.131.617.720.500.500.875.900']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Assessment of donor steatosis in liver transplantation: is it possible without liver biopsy? | BACKGROUND: Macrovesicular steatosis of the liver is associated with early dysfunction or poor function of the graft after transplantation; however, it can be quantified accurately only through a liver biopsy that sometimes may not be available and whose result is anyway known when the recipient has already been select... | ['Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Alanine Transaminase', 'Alcoholism', 'Biopsy, Needle', 'Cadaver', 'Diabetes Mellitus, Type 2', 'Fatty Liver', 'Female', 'Humans', 'Liver Transplantation', 'Male', 'Middle Aged', 'Obesity', 'Odds Ratio', 'ROC Curve', 'Retrospective Studies', 'Severity of Illness Ind... | 19,486,345 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.811.913.477.700.100'], ['C25.775.100.250', 'F03.900.100.350'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200... | ['Named Groups [M]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Moderate- and vigorous-intensity exercise behaviour according to the Transtheoretical Model: associations with smoking and BMI among Austrian adults. | BACKGROUND: Regular physical activity leads to a number of physiological benefits, such as reduced risk of coronary heart disease, diabetes mellitus and obesity. In Austria, there is little information about the prevalence of physically inactive people, as well as about who is more likely to belong to the inactive or i... | ['Adult', 'Age Distribution', 'Aged', 'Aged, 80 and over', 'Austria', 'Body Mass Index', 'Exercise', 'Female', 'Health Behavior', 'Humans', 'Male', 'Middle Aged', 'Models, Theoretical', 'Obesity', 'Physical Conditioning, Human', 'Prevalence', 'Prognosis', 'Risk Factors', 'Risk Reduction Behavior', 'Sedentary Behavior',... | 23,595,523 | [['M01.060.116'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['Z01.542.088'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['G11.427.410.698.277', 'I03.350'], ['F01.145.488'], ['B01.050.150.900.649.313.988.400.112... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Avian sarcoma and leukosis virus pol-endonuclease recognition of the tandem long terminal repeat junction: minimum site required for cleavage is also required for viral growth. | Integration of retroviral DNA is a site-specific reaction involving an endonuclease encoded by the viral pol gene (pol-endo). In vitro the pol-endo from avian sarcoma and leukosis viruses (ASLVs) cleaves both DNA strands near the U5-U3 junction of tandem long terminal repeats (LTR-LTR junction) in single-stranded and r... | ['Alpharetrovirus', 'Base Sequence', 'DNA', 'DNA, Viral', 'DNA-Binding Proteins', 'Endodeoxyribonucleases', 'Repetitive Sequences, Nucleic Acid', 'Retroviridae Proteins', 'Substrate Specificity', 'Virus Replication'] | 3,033,327 | [['B04.613.807.070', 'B04.820.650.070'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308'], ['D13.444.308.568'], ['D12.776.260'], ['D08.811.277.352.335.350', 'D08.811.277.352.355.325'], ['G02.111.570.080.708', 'G05.360.080.708'], ['D12.776.964.775'], ['G02.111.835'], ['G06.920.925']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Associations between viral infection and respiratory disease in young beef bulls. | Blood samples were taken from bull calves at two Meat and Livestock Commission performance testing centres, just after weaning at six months of age and at six weekly intervals until the end of the performance test seven months later. Sera were assayed by specific ELISAS for antibodies to bovine herpes virus 1 (BHV1), r... | ['Adenoviridae', 'Animals', 'Antibodies, Viral', 'Cattle', 'Cattle Diseases', 'Disease Outbreaks', 'Enzyme-Linked Immunosorbent Assay', 'Herpesvirus 1, Bovine', 'Male', 'Parainfluenza Virus 3, Human', 'Respiratory Syncytial Viruses', 'Respiratory Tract Infections', 'Seasons', 'Virus Diseases'] | 2,842,921 | [['B04.280.030'], ['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['N06.850.290'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['B04.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Beta-myosin heavy-chain gene mutations in patients with hypertrophic cardiomyopathy]. | INTRODUCTION AND OBJECTIVES: To determine the frequency of mutations in the beta-myosin heavy-chain gene (MYH7) in a cohort of patients with hypertrophic cardiomyopathy (HCM) and their families, and to investigate correlations between genotype and phenotype.METHODS: Single-strand conformation polymorphism analysis and ... | ['Adolescent', 'Adult', 'Aged', 'Cardiac Myosins', 'Cardiomyopathy, Hypertrophic', 'Cohort Studies', 'DNA Mutational Analysis', 'Data Interpretation, Statistical', 'Death, Sudden, Cardiac', 'Female', 'Genotype', 'Humans', 'Male', 'Middle Aged', 'Mutation', 'Myosin Heavy Chains', 'Pedigree', 'Phenotype', 'Polymorphism, ... | 17,125,710 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D05.750.078.730.475.475.124', 'D08.811.277.040.025.193.750.750.124', 'D12.776.210.500.600.470.249', 'D12.776.220.525.475.475.124'], ['C14.280.238.100', 'C14.280.484.048.750.070.160'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'],... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Atherosclerotic cardiovascular disease and sudden deaths among young adults in Wayne County. | Based on postmortem records at the Wayne County Medical Examiners' Office from 1982 to 1986, autopsy results indicated that the deaths of 129 persons aged 20-34 resulted from heart disease: 51 of these deaths were attributed to atherosclerotic cardiovascular disease (ASCVD), 29 to hypertensive cardiovascular disease, 2... | ['Adult', 'African Continental Ancestry Group', 'Coronary Artery Disease', 'Death, Sudden', 'Female', 'Humans', 'Male', 'Michigan', 'Retrospective Studies'] | 2,220,703 | [['M01.060.116'], ['M01.686.508.100'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['C23.550.260.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875.350.500', 'Z01.107.567.875.510.500'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500'... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Elastin purification and solubilization. | The functional form of elastin is a highly cross-linked polymer that organizes as sheets or fibers in the extracellular matrix. Purification of the mature protein is problematic because its insolubility precludes its isolation using standard wet-chemistry techniques. Instead, relatively harsh experimental approaches de... | ['Alkalies', 'Animals', 'Elastin', 'Extracellular Matrix', 'Hot Temperature', 'Microscopy, Electron', 'Molecular Imaging', 'Proteolysis', 'Solubility', 'Staining and Labeling'] | 29,310,779 | [['D01.045'], ['B01.050'], ['D05.750.078.421', 'D12.776.860.300.350'], ['A11.284.295.310'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['E01.370.350.515.402', 'E05.595.402'], ['E01.370.350.557', 'E05.601.555'], ['G02.111.720',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Anti-RH1 (anti-D) alloimmunization after transfusion of platelet concentrates from RH :1 donors]. | Anti-erythrocyte alloimmunization may occur following the transfusion of platelet concentrates, in response to the presence of residual erythrocytes. Immunization against RH1 (D) antigen is the most frequent, but transfusion of RH1 compatible platelet concentrates is not always possible because of supply constraints. W... | ['Aged', 'Erythrocytes', 'Female', 'Humans', 'Immunization', 'Male', 'Middle Aged', 'Platelet Transfusion', 'Rh-Hr Blood-Group System', 'Rho(D) Immune Globulin'] | 19,411,240 | [['M01.060.116.100'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.095.465.425.400', 'E05.478.550', 'N02.421.726.758.310', 'N06.850.780.200.425', 'N06.850.780.680.310'], ['M01.060.116.630'], ['E02.095.135.140.650'], ['D23.050.301.290.775', 'D23.050.705.230.77... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Irradiation-induced secretion of BMP4 by marrow cells causes marrow adipogenesis post-myelosuppression. | Pre-transplant myeloablation is associated with marrow adipogenesis, resulting in delayed engraftment of hematopoietic stem cells (HSCs). This is strongly undesirable, especially when the donor HSCs are fewer in numbers or have compromised functionality. The molecular mechanisms behind irradiation-induced marrow adipog... | ['Adipocytes', 'Adipogenesis', 'Animals', 'Bone Marrow Cells', 'Bone Morphogenetic Protein 4', 'Mice', 'Mice, Inbred C57BL', 'PPAR gamma', 'Secretory Rate', 'Simvastatin', 'Stromal Cells', 'T-Lymphocytes', 'Whole-Body Irradiation'] | 27,865,162 | [['A11.329.114'], ['G04.152.149'], ['B01.050'], ['A11.148', 'A15.378.316'], ['D12.644.276.954.200.400', 'D12.776.467.942.200.400', 'D23.529.942.200.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D12.776.826.239.588'], ['G03.857']... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A new enzymatic variant of Leishmania infantum Nicolle, 1908, agent of cutaneous leishmaniasis in northern Algeria]. | For the first time, the pathogenic agent of cutaneous leishmaniasis in the North of Algeria has been identified as Leishmania infantum s.1. The parasite was found to be a newly discovered enzymatic variant (zymodeme 24) differing by two electromorphs from a variant isolated in France (zymodeme 11) from the same type of... | ['Algeria', 'Animals', 'Electrophoresis, Starch Gel', 'Humans', 'Leishmania', 'Leishmaniasis', 'Leishmaniasis, Visceral'] | 3,985,532 | [['Z01.058.266.104'], ['B01.050'], ['E05.196.401.485', 'E05.301.300.402'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.268.475.868.488'], ['C01.610.752.300.500', 'C01.610.858.560', 'C01.920.813', 'C17.800.838.775.560'], ['C01.610.752.300.500.510', 'C01.920.813.510']] | ['Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Long-term air pollution exposure and acceleration of atherosclerosis and vascular inflammation in an animal model. | CONTEXT: Recent studies have suggested a link between inhaled particulate matter exposure in urban areas and susceptibility to cardiovascular events; however, the precise mechanisms remain to be determined.OBJECTIVE: To test the hypothesis that subchronic exposure to environmentally relevant particulate matter, even at... | ['Air Pollutants', 'Air Pollution', 'Animals', 'Aorta', 'Apolipoproteins E', 'Atherosclerosis', 'Echo-Planar Imaging', 'In Vitro Techniques', 'Inflammation', 'Lipids', 'Male', 'Mice', 'Mice, Knockout', 'Models, Animal', 'Muscle, Smooth, Vascular', 'Vasoconstriction'] | 16,414,948 | [['D27.888.284.101'], ['N06.850.460.100'], ['B01.050'], ['A07.015.114.056'], ['D10.532.091.500', 'D12.776.070.400.500', 'D12.776.521.120.500'], ['C14.907.137.126.307'], ['E01.370.350.825.500.200'], ['E05.481'], ['C23.550.470'], ['D10'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500.500', 'B01.050.1... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of Affymetrix data normalization methods using 6,926 experiments across five array generations. | BACKGROUND: Gene expression microarray technologies are widely used across most areas of biological and medical research. Comparing and integrating microarray data from different experiments would be very useful, but is currently very challenging due to the experimental and hybridization conditions, as well as data pre... | ['Computational Biology', 'Gene Expression Profiling', 'Oligonucleotide Array Sequence Analysis', 'Statistical Distributions'] | 19,208,124 | [['H01.158.273.180', 'L01.313.124'], ['E05.393.332'], ['E05.393.661.640', 'E05.393.760.640', 'E05.588.570.660', 'E05.601.640'], ['E05.318.740.994', 'G17.820', 'N05.715.360.750.750', 'N06.850.520.830.994']] | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Determination of urinary 4-pyridoxic acid levels as 4-pyridoxic acid lactone using high-performance liquid chromatography. | A high-performance liquid chromatography method for quantitation of urinary 4-pyridoxic acid excretion is presented. Urine samples were treated with HCl to form 4-pyridoxic acid lactone. Acid-treated urine samples were diluted and analyzed by cation-exchange chromatography involving post-column alkalinization and fluor... | ['Chromatography, High Pressure Liquid', 'Humans', 'Indicators and Reagents', 'Isonicotinic Acids', 'Pyridoxic Acid'] | 3,766,456 | [['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470.410'], ['D03.066.349', 'D03.383.725.394'], ['D03.066.349.600', 'D03.383.725.394.700', 'D03.383.725.705.645']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Modified-FOLFIRINOX in metastatic pancreatic cancer: A prospective study in Chinese population. | FOLFIRINOX chemotherapy has shown remarkable responses in patients with metastatic pancreatic cancer (MPC), and has significantly improved prognosis. However, FOLFIRINOX is currently not frequently applied in China because of its high incidence of adverse events, and there is no recognized optimization for this therapy... | ['Adult', 'Aged', 'Antineoplastic Combined Chemotherapy Protocols', 'Camptothecin', 'China', 'Female', 'Humans', 'Irinotecan', 'Liver Neoplasms', 'Lung Neoplasms', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Grading', 'Neoplasm Metastasis', 'Neoplasm Staging', 'Organoplatinum Compounds', 'Oxaliplatin', 'Pa... | 28,729,048 | [['M01.060.116'], ['M01.060.116.100'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D03.132.151'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.132.151.425'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.69... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A novel method for development of malaria vaccines using full-length cDNA libraries. | We describe a novel method to screen malaria DNA vaccine candidates using a full-length cDNA library and a murine malaria infection model. For the development of effective malaria vaccines, much effort has been made with meager success. The completion of genome sequencing of Plasmodium falciparum has provided invaluabl... | ['Animals', 'Antigens, Protozoan', 'Biolistics', 'Cytokines', 'Female', 'Gene Library', 'Malaria Vaccines', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred ICR', 'Rats', 'Rats, Wistar', 'Vaccines, DNA'] | 16,005,745 | [['B01.050'], ['D23.050.293'], ['E02.319.267.530.620.570.100', 'E05.393.350.100'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['G05.360.325'], ['D20.215.894.582.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['B01.050.0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Is home tooth bleaching gel cytotoxic? | Tooth whitening systems are widely used clinically and for home usage. The aim of this study was to determine the effects of two bleaching gels, each containing 10 percent and 15 percent carbamide peroxide, respectively, a 'bleaching gel' without carbamide peroxide, and carbamide peroxide alone on the viability of huma... | ['Analysis of Variance', 'Carbamide Peroxide', 'Cells, Cultured', 'Drug Combinations', 'Endothelium', 'Humans', 'Peroxides', 'Tooth Bleaching', 'Urea'] | 1,815,714 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['D01.248.497.158.685.750.318', 'D01.339.431.374.318', 'D01.650.550.750.300', 'D02.065.950.278', 'D02.389.338.154'], ['A11.251'], ['D26.310'], ['A10.272.491'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750', 'D01.339.431.37... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of the QRS Complex, ST-Segment, and T-Wave Among Patients with Left Bundle Branch Block with and without Acute Myocardial Infarction. | BACKGROUND: The modified Sgarbossa criteria have been validated as a rule for diagnosis of acute coronary occlusion (ACO) in left bundle branch block (LBBB). However, no analysis has been done on differences in the QRS complex, T-wave, or ST-segment concordance of < 1 mm in the derivation or validation studies. Further... | ['Aged', 'Bundle-Branch Block', 'Decision Support Techniques', 'Education, Medical, Continuing', 'Electrocardiography', 'Emergency Service, Hospital', 'Female', 'Heart Conduction System', 'Humans', 'Male', 'Myocardial Infarction', 'Retrospective Studies'] | 27,041,492 | [['M01.060.116.100'], ['C14.280.067.558.323', 'C14.280.123.500.323', 'C23.550.073.425.100'], ['E05.245', 'L01.313.500.750.190'], ['I02.358.212.350', 'I02.358.399.250'], ['E01.370.370.380.240', 'E01.370.405.240'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['A07.541.409'], ['B01.050.150.9... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 0 |
A Case of Pulmonary Hypertension Due to Fistulas Between Multiple Systemic Arteries and the Right Pulmonary Artery in an Adult Discovered for Occulted Dyspnoea. | BACKGROUND: Pulmonary hypertension (PH) can be caused by a fistula between the systemic and pulmonary arteries. Here, we report a case of PH due to multiple fistulas between systemic arteries and the right pulmonary artery where the ventilation/perfusion scan showed no perfusion in the right lung.METHODS: A 32-year-old... | ['Adult', 'Arterio-Arterial Fistula', 'Computed Tomography Angiography', 'Contrast Media', 'Dyspnea', 'Embolization, Therapeutic', 'Humans', 'Hypertension, Pulmonary', 'Male', 'Pulmonary Artery'] | 28,314,671 | [['M01.060.116'], ['C14.240.850.984.500', 'C14.907.933.110', 'C16.131.240.850.500', 'C23.300.575.950.150'], ['E01.370.350.350.810.335', 'E01.370.350.567.250', 'E01.370.350.600.350.700.810.335', 'E01.370.350.700.700.810.335', 'E01.370.350.700.810.810.568', 'E01.370.350.825.810.810.499'], ['D27.505.259.500', 'D27.720.259... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Changes in ADL dependence and aspects of usability following housing adaptation--a longitudinal perspective. | OBJECTIVE: To investigate longitudinal changes in activities of daily living (ADL) dependence and aspects of usability in housing among clients receiving housing adaptation grants in Sweden.METHODS: The ADL Staircase and the Usability in My Home instruments were used to collect data on three occasions: at baseline 1 mo... | ['Activities of Daily Living', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Financing, Government', 'Housing', 'Humans', 'Longitudinal Studies', 'Male', 'Middle Aged', 'Occupational Therapy', 'Sweden'] | 15,969,277 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N03.219.521.346'], ['J03.340', 'N01.224.791.400', 'N06.230.150.360', 'N06.850.505.400.800.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.7... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 1 |
Surface molecules on HaCaT keratinocytes after interaction with non-thermal atmospheric pressure plasma. | Non-thermal atmospheric-pressure plasmas have been developed that will be used in future for several purposes, e.g. medicine. Living tissues and cells are at the focus of plasma treatment, e.g. to improve wound healing, or induce apoptosis and growth arrest in tumour cells. Detailed investigations of plasma-cell intera... | ['Adult', 'Cadherins', 'Cell Adhesion Molecules', 'Cell Count', 'Cell Line', 'ErbB Receptors', 'Humans', 'Integrins', 'Keratinocytes', 'Plasma Gases', 'Reactive Oxygen Species'] | 22,973,947 | [['M01.060.116'], ['D12.776.395.550.200.200', 'D12.776.543.550.200.200', 'D23.050.301.350.200'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['A11.251.210'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Fullerene adlayers on various single-crystal metal surfaces prepared by transfer from L films. | Fullerene adlayers prepared by the simple Langmuir-Blodgett (LB) method onto various well-defined single-crystal metal surfaces were investigated by in situ scanning tunneling microscopy (STM). The surface morphologies of fullerene adsorbed onto metal surfaces depended largely on the adsorbate-substrate interactions, w... | ['Adsorption', 'Crystallization', 'Fullerenes', 'Gold', 'Iodine', 'Membranes, Artificial', 'Particle Size', 'Phase Transition', 'Platinum', 'Surface Properties'] | 15,461,506 | [['G01.030', 'G02.020'], ['E05.196.300', 'G02.171'], ['D01.268.150.250', 'J01.637.512.600.612.350'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['D01.268.380.400'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['G02.712'], ['G01.645', 'G02.734'], ['D01.268.556.690', 'D01.268.956.734', 'D01.552.544... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
NESCA: a new NEMO/IKKgamma and TRAF6 interacting protein. | NEMO/IKKgamma is the essential regulatory subunit of the IkB Kinase (IKK) complex, required for the activation of Nuclear Factor kB (NF-kB) in many physiological processes such as inflammation, immunity, apoptosis, or development. NEMO works at a converging point of the NF-kB pathway as it interacts with upstream signa... | ['Adaptor Proteins, Signal Transducing', 'Cell Line', 'Humans', 'I-kappa B Kinase', 'Polyubiquitin', 'Protein Binding', 'TNF Receptor-Associated Factor 6', 'Two-Hybrid System Techniques', 'Ubiquitination'] | 19,365,808 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['A11.251.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.494', 'D12.644.360.361', 'D12.776.476.378'], ['D12.776.947.500.500'], ['G02.111.679', 'G03.808'], ['D12.644.360.024.500.968', 'D12.776.157.057.500.968', 'D12.776.47... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genome-wide polysome profiling reveals an inflammation-responsive posttranscriptional operon in gamma interferon-activated monocytes. | We previously showed that ribosomal protein L13a is required for translational silencing of gamma interferon (IFN-gamma)-induced ceruloplasmin (Cp) synthesis in monocytes. This silencing also requires the presence of the GAIT (IFN-gamma activated inhibitor of translation) element in the 3' untranslated region (UTR) of ... | ["3' Untranslated Regions", 'Ceruloplasmin', 'Chemokines', 'Computer Simulation', 'Electrophoretic Mobility Shift Assay', 'Gene Silencing', 'Humans', 'Inflammation', 'Interferon-gamma', 'Monocytes', 'Oligonucleotide Array Sequence Analysis', 'Operon', 'Polyribosomes', 'RNA, Messenger', 'Receptors, Chemokine', 'Ribosoma... | 19,001,086 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['D08.811.682.226', 'D12.776.124.050.130', 'D12.776.124.790.106.214', 'D12.776.157.160', 'D12.776.377.715.085.214', 'D12.776.556.151'], ['D12.644.276.374.200', 'D12.776.467.374.200', 'D23.125.300',... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Breastfeeding promotion and protection in the Czech Republic. | The purpose of the article is to present the National Breastfeeding Promotion Programme in the Czech Republic in the course of the last decade. It summarizes the main strategies, education and training activities of the National Breastfeeding Committee, its collaboration with the Government, Parliament, IBFAN and UNICE... | ['Breast Feeding', 'Child Nutrition Sciences', 'Czech Republic', 'Health Education', 'Health Promotion', 'Humans', 'Infant', 'Infant Nutritional Physiological Phenomena', 'Infant, Newborn', 'National Health Programs', 'United Nations', 'World Health Organization'] | 15,242,030 | [['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['H02.533.252'], ['Z01.542.248.395'], ['I02.233.332', 'N02.421.726.407'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G07.203.650.220.500'], ['M01.060.703.520'],... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
SUMOylation of large tumor suppressor 1 at Lys751 attenuates its kinase activity and tumor-suppressor functions. | Large tumor suppressor (Lats) plays a critical role in maintaining cellular homeostasis and is the core to mediate Hippo growth-inhibitory signaling pathway. SUMOylation is a reversible and dynamic process that regulates a variety of cell functions. Here, we show that SUMOylation of Lats1 affects its kinase activity sp... | ['Animals', 'Apoptosis', 'Carcinoma, Hepatocellular', 'Cell Proliferation', 'HEK293 Cells', 'Hep G2 Cells', 'Humans', 'Liver Neoplasms', 'Lysine', 'Mice, Nude', 'Phosphorylation', 'Protein-Serine-Threonine Kinases', 'SUMO-1 Protein', 'Signal Transduction', 'Sumoylation', 'Time Factors', 'Transfection', 'Tumor Burden', ... | 27,847,303 | [['B01.050'], ['G04.146.954.035'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251.210.172.750', 'A11.436.334'], ['A11.251.860.180.432', 'A11.436.348.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Phylogenomics of an extra-Antarctic notothenioid radiation reveals a previously unrecognized lineage and diffuse species boundaries. | BACKGROUND: The impressive adaptive radiation of notothenioid fishes in Antarctic waters is generally thought to have been facilitated by an evolutionary key innovation, antifreeze glycoproteins, permitting the rapid evolution of more than 120 species subsequent to the Antarctic glaciation. By way of contrast, the seco... | ['Animals', 'Antarctic Regions', 'Base Sequence', 'Calibration', 'Fishes', 'Genetic Loci', 'Genetic Markers', 'Genetic Variation', 'Genome', 'Haplotypes', 'Likelihood Functions', 'Mitochondria', 'Phylogeny', 'Phylogeography', 'Polymorphism, Single Nucleotide', 'Sequence Analysis, DNA', 'Species Specificity', 'Time Fact... | 30,630,407 | [['B01.050'], ['Z01.158'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.978.155'], ['B01.050.150.900.493'], ['G05.360.340.024.380'], ['D23.101.387', 'G05.695.450'], ['G05.365'], ['G05.360.340'], ['G05.380.360'], ['E05.318.740.500.475', 'E05.318.740.600.400', 'E05.599.835.500', 'N05.715.360.750.530.4... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Vascularization of the Damaged Nerve under the Effect of Experimental Cell Therapy. | Quantitative analysis of blood vessels in the distal segment of rat sciatic nerve after its ligation for 40 sec and subperineurial administration of mesenchymal stem cells or dissociated cells of rat embryonic spinal cord was carried our by immunohistochemical tracing of von Willebrand factor, a marker of endothelial c... | ['Animals', 'Cell- and Tissue-Based Therapy', 'Immunohistochemistry', 'Mesenchymal Stem Cells', 'Nerve Regeneration', 'Peripheral Nerve Injuries', 'Rats', 'Rats, Wistar', 'Sciatic Nerve', 'Spinal Cord', 'von Willebrand Factor'] | 29,797,137 | [['B01.050'], ['E02.095.147'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['A11.329.830.500', 'A11.872.590.500'], ['G11.561.585... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid screening of urine specimens for bacteriuria by the cellenium system. | This study evaluated the performance of the Cellenium 160 US urine screening system in comparison to that of the semiquantitative culture method. The performance characteristics of the Cellenium system for all clinically significant uropathogens were 89.5% sensitivity, 94.4% specificity, 97.1% negative predictive value... | ['Bacteriuria', 'Clinical Laboratory Techniques', 'Culture Media', 'Gram-Negative Bacteria', 'Gram-Positive Cocci', 'Humans', 'Mass Screening', 'Sensitivity and Specificity', 'Time Factors', 'Urinary Tract Infections', 'Urine'] | 16,207,999 | [['C01.915.219', 'C12.777.892.219', 'C13.351.968.892.219'], ['E01.370.225', 'E05.200'], ['D27.720.470.305', 'E07.206'], ['B03.440'], ['B03.510.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.308.980.438... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Regional distribution and cellular localization of beta2-adrenoceptors in the adult zebrafish brain (Danio rerio). | The beta(2)-adrenergic receptors (ARs) are G-protein-coupled receptors that mediate the physiological responses to adrenaline and noradrenaline. The present study aimed to determine the regional distribution of beta(2)-ARs in the adult zebrafish (Danio rerio) brain by means of in vitro autoradiographic and immunohistoc... | ['Animals', 'Autoradiography', 'Binding Sites', 'Brain', 'Humans', 'Neurons', 'Protein Isoforms', 'Receptors, Adrenergic, beta-2', 'Zebrafish'] | 20,187,137 | [['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['G02.111.570.120'], ['A08.186.211'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.675', 'A11.671'], ['D12.776.800'], ['D12.776.543.750.670.300.300.340.200', 'D12.776.543.750.695.150.300.340.725', 'D12.776.543.750.720.330.300.340.200'], ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevention, assessment, and treatment of central venous catheter occlusions in neonatal and young pediatric patients. | Central venous catheter occlusions disrupt delivery of needed therapies to vulnerable neonatal and young pediatric patients. Nursing practices that minimize risk of catheter occlusion include proper infusion and flushing techniques. Treatment strategies vary on the basis of the source of the occlusion. Mechanical occlu... | ['Catheterization, Central Venous', 'Child, Preschool', 'Humans', 'Infant', 'Infant, Newborn', 'Nursing'] | 21,734,521 | [['E02.148.167', 'E04.100.814.529.875', 'E04.502.382.875', 'E05.157.313'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['H02.478', 'N04.452.758.377']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Effects of pinealectomy on the rat oestrous cycle and pituitary gonadotrophin release. | In 4-day cyclic rats kept in a room with the lights on from 05.00 to 19.00 h, sham pinealectomy or pinealectomy on the morning of pro-oestrus did not alter the length of the oestrous cycle for 44 days or the time and magnitude of the rises in LH, FSH and prolactin in the circulation in the afternoon on pro-oestrous day... | ['Animals', 'Castration', 'Circadian Rhythm', 'Denervation', 'Environment, Controlled', 'Estrus', 'Female', 'Follicle Stimulating Hormone', 'Gonadotropins, Pituitary', 'Hypothalamus, Middle', 'Luteinizing Hormone', 'Neurons, Afferent', 'Ovulation', 'Pineal Gland', 'Pituitary Gland', 'Pregnancy', 'Prolactin', 'Rats'] | 944,753 | [['B01.050'], ['E04.270.282', 'E04.950.165'], ['G07.180.562.190'], ['E04.525.210'], ['N06.230.150'], ['G08.686.195.500'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['D06.472.699.322.576', 'D06.472.699.631.525.343', 'D12.644.548.691.525.343'], ['A08.186.211.180.497.352', ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Fast detection of sugar content in fruit vinegar using NIR spectroscopy]. | For the fast and exact detection of sugar content of fruit vinegar, near infrared (NIR) spectroscopy technique combined with least squares support vector machines (LS-SVM) algorithm was used to build the prediction model of sugar content in the present research. NIR spectroscopy is a nondestructive, fast and accurate t... | ['Acetic Acid', 'Algorithms', 'Fruit', 'Models, Chemical', 'Principal Component Analysis', 'Spectroscopy, Near-Infrared', 'Sucrose', 'Time Factors'] | 18,975,809 | [['D02.241.081.018.165', 'D10.251.400.045.500'], ['G17.035', 'L01.224.050'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['E05.599.495'], ['E05.318.740.562'], ['E01.370.350.750', 'E05.196.867.851'], ['D09.698.629.305.770', 'D09.947.750.770'], ['G01.910.857']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
[Shigellosis and other acute intestinal infections in the Republic of Tajikistan: the epidemiological patterns]. | Acute enteric infections (AEI), including shigellosis, are characterized by their extremely wide spread in Tajikistan. Their hyperendemicity is due to a high activity of the water route of transmission under the conditions of hot climate. The morbidity level of AEI both in the republic as a whole and in its individual ... | ['Acute Disease', 'Child, Preschool', 'Dysentery, Bacillary', 'Humans', 'Infant', 'Intestinal Diseases', 'Morbidity', 'Shigella flexneri', 'Tajikistan', 'Typhoid Fever', 'Water Microbiology', 'Water Supply'] | 10,876,848 | [['C23.550.291.125'], ['M01.060.406.448'], ['C01.150.252.400.310.229', 'C06.405.205.331.479', 'C06.405.469.300.479'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C06.405.469'], ['E05.318.308.985.525', 'N01.224.935.597', 'N06.850.505.400.975.525', 'N06.850.520.308.985.525'], ['B03.440.450.425.850... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 |
Diabetes, hepatocellular carcinoma, and mortality in hepatitis C-infected patients: A population-based cohort study. | BACKGROUND AND AIM: The effect of diabetes mellitus (DM) on the development of hepatocellular carcinoma (HCC) and all-cause mortality after HCC development in chronic hepatitis C virus (HCV)-infected patients remains inconclusive. This cohort study aimed to investigate these issues using the Taiwanese National Health I... | ['Aged', 'Carcinoma, Hepatocellular', 'Cohort Studies', 'Diabetes Complications', 'Diabetes Mellitus', 'Female', 'Hepatitis C, Chronic', 'Humans', 'Liver Neoplasms', 'Male', 'Middle Aged', 'Models, Statistical', 'Risk', 'Time Factors'] | 27,930,829 | [['M01.060.116.100'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C19.246.099'], ['C18.452.394.750', 'C19.246'], ['C01.221.250.750.120', 'C01.925.440.440.120', 'C01.925.782.350.350.120', 'C06.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Long-term results of paclitaxel plus cisplatin with concurrent radiotherapy for loco-regional esophageal squamous cell carcinoma. | AIM: To evaluate the long-term effectiveness and late toxicities of paclitaxel (PTX) plus cisplatin (DDP) with concurrent radiotherapy for locally advanced esophageal squamous cancer.METHODS: Between 2008 and 2011, 76 patients were enrolled in a phase II study on the treatment of loco-regionally advanced esophageal can... | ['Adult', 'Aged', 'Antineoplastic Agents', 'Antineoplastic Combined Chemotherapy Protocols', 'Carcinoma, Squamous Cell', 'Chemoradiotherapy', 'Cisplatin', 'Disease-Free Survival', 'Dose Fractionation, Radiation', 'Esophageal Neoplasms', 'Esophageal Squamous Cell Carcinoma', 'Female', 'Follow-Up Studies', 'Humans', 'Mal... | 28,210,091 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.954.248'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E02.186.079', 'E02.319.164', 'E02.815.160'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
DNA-binding proteins specified by herpesvirus saimiri. | Herpesvirus saimiri-specific proteins from the nuclear fractions of productively infected owl monkey kidney cells were dissociated from virus and host DNA by treatment with 2 M-NaCl or separation on Urografin density gradients. Empty virus capsids remained intact and could be separated from major non-structural protein... | ['Animals', 'Aotus trivirgatus', 'Cell Fractionation', 'Cell Line', 'Cell Nucleus', 'Chromatography, Affinity', 'DNA', 'DNA-Binding Proteins', 'Herpesvirus 2, Saimiriine', 'Phosphoproteins', 'Viral Proteins', 'Viral Structural Proteins'] | 6,319,554 | [['B01.050'], ['B01.050.150.900.649.313.988.400.600.037.092'], ['E05.242.251'], ['A11.251.210'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['E05.196.181.400.170'], ['D13.444.308'], ['D12.776.260'], ['B04.280.210.400.700.400', 'B04.280.382.400.700.400', 'B04.613.204.500.700.400'], ['D12.776.744'], ['D12.776.96... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evaluation and treatment of osteoporosis in patients with a fragility hip fracture. | OBJECTIVE: To determine whether patients with fragility hip fractures underwent assessment and treatment of osteoporosis during initial hospitalization or recommendations for such intervention were made to the primary care provider (PCP) at the time of hospital dismissal.METHODS: A review of medical records of patients... | ['Adult', 'Aged', 'Aged, 80 and over', 'Delivery of Health Care', 'Female', 'Follow-Up Studies', 'Hip Fractures', 'Humans', 'Male', 'Middle Aged', 'Orthopedics', 'Osteoporosis', 'Retrospective Studies', 'Surveys and Questionnaires'] | 16,638,723 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['N04.590.374', 'N05.300'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['C26.404.061.425', 'C26.531.750', 'C26.558.276.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['H02.403.81... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Availability and limitations of thallium-201 myocardial SPECT quantitative analysis: assessment as daily routine procedure for ischemic heart disease. | To determine the availability and limitations of the detection of ischemic lesions by stress thallium-201 myocardial SPECT as the daily routine procedure, we compared and evaluated the detectability of the quantitative analysis (%uptake and washout rate (WR)) and visual evaluation in 104 patients with effort angina and... | ['Aged', 'Coronary Disease', 'Exercise Test', 'Female', 'Humans', 'Male', 'Middle Aged', 'Sensitivity and Specificity', 'Thallium Radioisotopes', 'Tomography, Emission-Computed, Single-Photon'] | 1,863,518 | [['M01.060.116.100'], ['C14.280.647.250', 'C14.907.585.250'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.800', 'E05.318.740.872', 'G17.800', 'N05.715.360.325.700', 'N05.715.360.750.725', 'N06.850.520.445.800', 'N06.8... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Chronic diseases are not being managed effectively in either high-risk or low-risk populations in South Africa. | BACKGROUND: Primary healthcare is the foundation of a country's healthcare system. Without an efficient and cost-effective programme, the level of healthcare offered across all levels of health management is adversely affected.OBJECTIVE: To analyse the effectiveness of the management of hypertension and diabetes mellit... | ['Adult', 'Case-Control Studies', 'Chronic Disease', 'Coronary Disease', 'Diabetes Mellitus', 'Disease Management', 'Female', 'Health Services Needs and Demand', 'Humans', 'Hypertension', 'Male', 'Middle Aged', 'Outcome Assessment, Health Care', 'Primary Health Care', 'Risk Assessment', 'Risk Factors', 'South Africa'] | 24,300,634 | [['M01.060.116'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.291.500'], ['C14.280.647.250', 'C14.907.585.250'], ['C18.452.394.750', 'C19.246'], ['N04.590.607'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['M01.060.1... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Late presentation with whole limb gangrene following open traumatic hemipelvectomy. | Traumatic hemipelvectomy is a rare type of devastating injury with a very high mortality rate and often the result of high energy transfer trauma. Most patients, who survive this injury, do so on the basis of prompt and immediate advanced medical care. Abdominal and pelvic visceral injuries are frequently seen in those... | ['Accidents, Traffic', 'Adolescent', 'Female', 'Gangrene', 'Hemipelvectomy', 'Humans', 'Leg Injuries', 'Multiple Trauma'] | 22,350,051 | [['N06.850.135.392'], ['M01.060.057'], ['C23.550.717.427'], ['E04.555.080.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.558'], ['C26.640']] | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Radiofrequency ablation of the kidney: acute and chronic histology in porcine model. | OBJECTIVES: To our knowledge, the chronic histopathologic effects of radiofrequency ablation (RFA) of renal parenchyma have not been extensively documented. In this study, we report the light and electron microscopic features of renal RFA in acute and chronic porcine models.METHODS: Eleven animals underwent renal RFA o... | ['Animals', 'Catheter Ablation', 'Cell Death', 'Cell Nucleus', 'Chromatin', 'Cytoplasm', 'Eosinophilia', 'Kidney', 'Laparoscopy', 'Necrosis', 'Organelles', 'Swine'] | 11,068,326 | [['B01.050'], ['E02.808.750.500', 'E04.014.760.500'], ['G04.146'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['A11.284.430.214'], ['C15.378.553.231'], ['A05.810.453'], ['E01.370.388.250.520', 'E04.502.250.520'], ['C23.550.717'], ['... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anterior Segment Optical Coherence Tomography for Targeted Transconjunctival Suture Placement in Overfiltering Trabeculectomy Blebs. | PURPOSE: To demonstrate the utility of swept-source anterior segment optical coherence tomography (SS-AS-OCT) in guiding placement of transconjunctival sutures in hypotonous patients after a trabeculectomy.PATIENTS AND METHODS: This is a longitudinal case series of 10 eyes from 10 patients who required transconjunctiva... | ['Aged', 'Aged, 80 and over', 'Anterior Eye Segment', 'Conjunctiva', 'Female', 'Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Male', 'Middle Aged', 'Ocular Hypotension', 'Suture Techniques', 'Tomography, Optical Coherence', 'Trabeculectomy'] | 28,263,262 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['A09.371.060'], ['A09.371.060.200', 'A09.371.337.168'], ['C11.525.381.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['M01.060.116.630'], ['C11.540'], ['E04.987.775'], ['E01.370.350.589.249.500', 'E01.370.350.825.805.500', 'E05.642.249.500'], ['E04.5... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Early type I Interferon response induces upregulation of human â-defensin 1 during acute HIV-1 infection. | HIV-1 is able to evade innate antiviral responses during acute infection to establish a chronic systemic infection which, in the absence of antiretroviral therapy (ART), typically progresses to severe immunodeficiency. Understanding these early innate immune responses against HIV-1 and their mechanisms of failure is re... | ['HIV Infections', 'HIV-1', 'Humans', 'Interferon Type I', 'Monocytes', 'Up-Regulation', 'beta-Defensins'] | 28,253,319 | [['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['B04.820.650.589.650.350.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.440.890', 'D12.776.467.374.440.890', 'D23.529.374.440.890'], ['A11.118.637.555.652', 'A11.148.5... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Characterization and suppression of stripe artifact in velocity-selective magnetization-prepared unenhanced MR angiography. | PURPOSE: To characterize and suppress stripe artifact associated with velocity-selective (VS) magnetization for unenhanced MRA.METHODS: Extended phase graph formalism was used to show that the stripe artifact contains multiples of the fundamental frequency that is determined by the area of unipolar VS gradient. Four VS... | ['Animals', 'Artifacts', 'Chickens', 'Humans', 'Image Processing, Computer-Assisted', 'Magnetic Resonance Angiography', 'Models, Biological', 'Muscles', 'Phantoms, Imaging', 'Thigh'] | 29,536,569 | [['B01.050'], ['E05.047'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['E01.370.350.825.500.500', 'E01.370.370.050.500'], ['E05.599.395'], ['A02.633', 'A10.690'], ['E07.671'], ['A01.378.610.750']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Nickel and the microbial toxin, MALP-2, stimulate proangiogenic mediators from human lung fibroblasts via a HIF-1alpha and COX-2-mediated pathway. | Hypoxia-inducible factor (HIF-1alpha) and cyclooxygenase-2 (COX-2) have been implicated in the regulation of inflammatory-like processes that lead to angiogenesis and fibrotic disorders. Here we demonstrate that in human lung fibroblasts (HLFs) treated with mixed exposures to chemical and microbial stimuli, HIF-1alpha ... | ['Analysis of Variance', 'Cells, Cultured', 'Chemokines, CXC', 'Cyclooxygenase 2', 'Databases, Genetic', 'Fibroblasts', 'Gene Silencing', 'Humans', 'Hypoxia-Inducible Factor 1, alpha Subunit', 'Inflammation Mediators', 'Lipopeptides', 'Lung', 'Neovascularization, Physiologic', 'Nickel', 'Oligonucleotide Array Sequence ... | 18,832,182 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['A11.251'], ['D12.644.276.374.200.120', 'D12.776.467.374.200.120', 'D23.125.300.120', 'D23.469.200.120', 'D23.529.374.200.120'], ['D08.811.600.720.750'], ['L01.313.500.750.300.188.400.325', 'L01.470.750.750.325'], ['A11.329.228'], ['G05.308.203.374'],... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
An optimal combination of MCCB and CANTAB to assess functional capacity in older individuals with schizophrenia. | INTRODUCTION: Cognitive deficits predict functional capacity in patients with schizophrenia including in late life. The MATRICS Consensus Cognitive Battery (MCCB) and the Cambridge Neuropsychological Test Automated Battery (CANTAB) are widely used to assess cognition in this population. The aim of this study was to det... | ['Aged', 'Brief Psychiatric Rating Scale', 'Cognition', 'Cognition Disorders', 'Female', 'Humans', 'Male', 'Memory, Short-Term', 'Middle Aged', 'Neuropsychological Tests', 'Regression Analysis', 'Schizophrenia', 'Schizophrenic Psychology', 'Verbal Learning'] | 27,428,251 | [['M01.060.116.100'], ['F04.711.513.653.083'], ['F02.463.188'], ['F03.615.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.425.540.407'], ['M01.060.116.630'], ['F04.711.513'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['F03.700.750'], ['F04.824'], ['F02.463.425.952']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Electrocardiographic findings of palonosetron in cancer patients. | PURPOSE: Nausea and vomiting are among the major problems occurring during and after the chemotherapy treatments of cancer patients. The recently developed 5-HT(3) antagonists have proved much more effective than former agents. Several studies have shown that these agents cause certain ECG changes. We aimed to evaluate... | ['Adult', 'Aged', 'Aged, 80 and over', 'Antiemetics', 'Antineoplastic Agents', 'Blood Pressure', 'Electrocardiography', 'Female', 'Heart Rate', 'Humans', 'Isoquinolines', 'Male', 'Middle Aged', 'Nausea', 'Neoplasms', 'Palonosetron', 'Quinuclidines', 'Serotonin 5-HT3 Receptor Antagonists', 'Time Factors', 'Vomiting', 'Y... | 21,773,677 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.696.663.050.030', 'D27.505.954.427.095', 'D27.505.954.483.200'], ['D27.505.954.248'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.98... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Serum copper, zinc and metallothionein serve as potential biomarkers for hepatocellular carcinoma. | BACKGROUND: Copper (Cu) and zinc (Zn) are essential nutrients and cofactors of enzymatic reactions with their binding partner. Metallothionein (MT) plays an important role in protecting against heavy metals and oxidative injury, however it may also portend drug resistance and a worse prognosis for hepatocellular carcin... | ['Aged', 'Biomarkers, Tumor', 'Carcinoma, Hepatocellular', 'Copper', 'Female', 'Humans', 'Liver Neoplasms', 'Male', 'Metallothionein', 'Phenylurea Compounds', 'Quinolines', 'Zinc'] | 32,857,769 | [['M01.060.116.100'], ['D23.101.140'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['D12.776.556.670'], ['D02.065.9... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Poultry litter as a source of gastrointestinal helminth infections. | The aim of this study carried out in 6 commercial layer houses was to examine the effect of litter management on water content, helminth egg count and litter infectiousness with the intestinal nematodes Ascaridia galli, Heterakis gallinarum, and Capillaria spp. Three types of litter management were established in each ... | ['Animal Husbandry', 'Animals', 'Chickens', 'Feces', 'Female', 'Floors and Floorcoverings', 'Gastrointestinal Diseases', 'Helminthiasis, Animal', 'Helminths', 'Housing, Animal', 'Parasite Egg Count', 'Poultry Diseases', 'Time Factors'] | 19,251,370 | [['J01.040.090'], ['B01.050'], ['B01.050.150.900.248.350.150', 'B01.050.150.900.248.690.192'], ['A12.459'], ['J01.086.339.140'], ['C06.405'], ['C01.610.335.349', 'C01.610.701.377', 'C22.674.377'], ['B01.050.500.500'], ['J03.340.250', 'N06.230.150.360.250'], ['E01.370.225.932.600', 'E05.200.932.600'], ['C22.131.728'], [... | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
A new strategy to construct a C=C-CF3 subunit via CuBr-catalyzed domino reaction of homopropargyl amines: an efficient synthesis of trifluoromethyl containing building blocks 4-trifluoromethyl-2,3-dihydro-pyrroliums. | A new strategy for the construction of a C=C-CF3 subunit has been developed via CuBr-catalyzed domino cyclization-trifluoromethylation of homopropargyl amines with Umemoto's reagent. 4-Trifluoromethyl-2,3-dihydro-pyrroliums were produced in high yields. The usefulness of these products has been demonstrated by the tran... | ['Amines', 'Bromides', 'Catalysis', 'Copper', 'Cyclization', 'Halogenation', 'Methylation', 'Pyrroles'] | 24,513,681 | [['D02.092'], ['D01.139.300.050', 'D01.248.497.158.125'], ['G02.130'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['G02.111.180', 'G02.607.133', 'G03.208'], ['G02.111.323', 'G03.360'], ['G02.111.035.538', 'G02.607.094.538', 'G03.059.538'], ['D03.383.129.578']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Foot length measurements of newborns of high and low risk pregnancies. | OBJECTIVE: Comparing foot length measurements of newborns in high and low risk pregnancies at a public hospital in Goi?nia, GO, Brazil.METHOD: A cross-sectional study carried out between April, 2013 and May, 2015, with a sample consisting of 180 newborns; 106 infants of women from high-risk pregnancies and 74 of women ... | ['Brazil', 'Cross-Sectional Studies', 'Female', 'Foot', 'Hospitals, Public', 'Humans', 'Infant, Newborn', 'Organ Size', 'Pregnancy', 'Pregnancy, High-Risk', 'Risk Assessment'] | 28,300,963 | [['Z01.107.757.176'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['A01.378.610.250'], ['N02.278.421.510'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690'], ['G08.686.784.769'], ... | ['Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[Analysis and radiologic staging of the type and severity of aspiration]. | The estimated number of the incidence of undiagnosed chronic aspiration pneumonia after cerebral or cerebrovascular injury seems very high. According to American statistics, at least 6% of these patients die from aspiration pneumonia within the first year. The high temporal resolution of cineradiography with frame rate... | ['Barium Sulfate', 'Brain Damage, Chronic', 'Chronic Disease', 'Cineradiography', 'Contrast Media', 'Esophagus', 'Humans', 'Pharynx', 'Pneumonia, Aspiration', 'Recurrence', 'Velopharyngeal Insufficiency'] | 7,501,801 | [['D01.103.075', 'D01.875.800.800.850.075'], ['C10.228.140.140'], ['C23.550.291.500'], ['E01.370.350.700.225.469'], ['D27.505.259.500', 'D27.720.259'], ['A03.556.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.556.750', 'A04.623', 'A14.724'], ['C01.748.610.529', 'C08.381.677.529', 'C08.730.610.529'], ... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anatomical Characterization and Three-Dimensional Modeling of the Muscles at the Corner of the Mouth: An Iodine Staining Technique Based on Micro-Computed Tomography. | The anatomy of the modiolus and surrounding muscles is complicated and contributes to the morphology of the mouth corner. The authors used iodine staining and micro-computed tomography to observe the anatomy of the modiolus and surrounding muscles. Based on the micro-computed tomographic images and the three-dimensiona... | ['Cheek', 'Coloring Agents', 'Humans', 'Imaging, Three-Dimensional', 'Iodine', 'Models, Anatomic', 'Mouth', 'Muscle, Skeletal', 'Staining and Labeling', 'X-Ray Microtomography'] | 29,927,831 | [['A01.456.505.173', 'A14.194'], ['D27.720.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['D01.268.380.400'], ['J01.897.280.500.545.129', 'L01.178.820.090.545.129'], ['A01.456.505.631', 'A03.556.500', 'A14.549'], ['A02.633.567', 'A10.690.552.500'], ['E01.370.225.500.620... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Circadian rhythms of food and 1% NaCl intake, urine and electrolyte excretion, plasma renin activity and insulin concentration in adrenalectomized rats. | The circadian rhythms of food and 1% NaCl intake, and urine, Na+, Cl- and K+ excretion were followed up in male Wistar rats before and one week after bilateral adrenalectomy at 4-hour intervals during two consecutive days. The circadian rhythms of plasma renin activity (PRA) and plasma immunoreactive insulin (IRI) were... | ['Adrenalectomy', 'Animals', 'Chlorides', 'Circadian Rhythm', 'Feeding Behavior', 'Insulin', 'Male', 'Potassium', 'Rats', 'Rats, Inbred Strains', 'Renin', 'Sodium', 'Sodium Chloride'] | 3,885,682 | [['E04.270.115'], ['B01.050'], ['D01.210.450.150', 'D01.248.497.158.215'], ['G07.180.562.190'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['B01.050.150.900.649.313.9... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Knowledge, attitudes, risk perceptions, and practices of adults toward COVID-19: a population and field-based study from Iran. | OBJECTIVES: To determine peoples' knowledge, attitudes, risk perceptions, and practices to provide policymakers pieces of field-based evidence and help them in the management of the COVID-19 epidemic.METHODS: This population-based survey was conducted using multi-stage stratified and cluster sampling in Shiraz, Iran. A... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'COVID-19', 'Coronavirus Infections', 'Cross-Sectional Studies', 'Epidemics', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Iran', 'Male', 'Middle Aged', 'Pandemics', 'Pneumonia, Viral', 'Risk Assessment', 'Socioeconomic Factors', 'Surveys and Questio... | 32,583,009 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163', 'C08.381.677.807.500', 'C08.730.214', 'C08.730.610.763.500'], ['C01.925.782.600.550.200'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
[Pathomorphologic course study in fattening pigs after olaquindox poisoning]. | In an investigation over five months the adrenal toxic effect of the quinoxaline derivate olaquindox in pigs of different ages (10 and 16 weeks) after accidental feeding of a 15-fold overdosage of olaquindox is demonstrated. The substance induced clinical and hematological changes comparable with Addison's disease. A r... | ['Adrenal Glands', 'Animal Feed', 'Animals', 'Drug Overdose', 'Hyperkalemia', 'Hyponatremia', 'Quinoxalines', 'Swine', 'Swine Diseases', 'Weight Gain'] | 2,048,109 | [['A06.300.071'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['C25.775.383', 'E02.319.306.500.500'], ['C18.452.950.396'], ['C18.452.950.620'], ['D03.633.100.857'], ['B01.050.150.900.649.313.500.880'], ['C22.905'], ['C23.888.144.243.926', 'G07.345.249.314.120.200.926']] | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Application of synthetic materials for prophylaxis of adhesion disease]. | In 55-93% of the patients after laparotomy performance the pathological adhesion process is observed. The local reactions of peritoneum (its blood supply disturbance, infection presence) as well as systemic disorders (biochemical, genetic, etc.) are pathogenetically important causes of this disease. There is no a secur... | ['Biocompatible Materials', 'Cellulose, Oxidized', 'Humans', 'Hyaluronic Acid', 'Peritoneal Diseases', 'Peritoneum', 'Tissue Adhesions', 'Treatment Outcome'] | 20,222,191 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D05.750.078.562.180.200', 'D09.698.365.180.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.698.373.475'], ['C06.844'], ['A01.923.047.025.600', 'A10.615.789.596'], ['C23.550.355.274.840'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Mapping the pH Sensors Critical for Host Cell Entry by a Complex Nonenveloped Virus. | Bluetongue virus (BTV), in the family Reoviridae, is an insect-borne, double-capsid virus causing hemorrhagic disease in livestock around the world. Here, we elucidate how outer capsid proteins VP2 and VP5 coordinate cell entry of BTV. To identify key functional residues, we used atomic-level structural data to guide m... | ['Bluetongue virus', 'Capsid Proteins', 'Cell Line', 'Cell Membrane', 'DNA Viruses', 'Host Microbial Interactions', 'Hydrogen-Ion Concentration', 'Protein Binding', 'Reoviridae', 'Virion', 'Virus Internalization'] | 30,518,645 | [['B04.820.223.719.550.100'], ['D12.776.964.970.600.550'], ['A11.251.210'], ['A11.284.149'], ['B04.280'], ['G06.373', 'G16.527'], ['G02.300'], ['G02.111.679', 'G03.808'], ['B04.820.223.719'], ['A21.249'], ['G06.920.881']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer. | Notch signalling is aberrantly activated in human non-small cell lung cancer (NSCLC). Nevertheless, the prognostic roles of mRNA expression of four Notch receptors in NSCLC patients remain elusive. In this report, we reported the prognostic roles of Notch receptors in a total of 1,926 NSCLC patients through "The Kaplan... | ['Adenocarcinoma', 'Carcinoma, Non-Small-Cell Lung', 'Carcinoma, Squamous Cell', 'Gene Expression Profiling', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Kaplan-Meier Estimate', 'Lung Neoplasms', 'Outcome Assessment, Health Care', 'Prognosis', 'Proportional Hazards Models', 'Proto-Oncogene Proteins', 'RNA, Mes... | 28,061,457 | [['C04.557.470.200.025'], ['C04.588.894.797.520.109.220.249', 'C08.381.540.140.500', 'C08.785.520.100.220.500'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.393.332'], ['G05.308.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Do generic firms and the Spanish public purchaser respond to consumer price differences of generics under reference pricing? | OBJECTIVES: To assess the impact of competition on the consumer price and the average price paid by the National Health System (NHS) under reference pricing in the Spanish generic market.METHODS: Descriptive analysis of the time trend in consumer prices before and after the application of reference pricing for the eigh... | ['Choice Behavior', 'Databases, Factual', 'Drugs, Generic', 'Economic Competition', 'Humans', 'National Health Programs', 'Spain'] | 20,630,613 | [['F02.463.785.373.346'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['D26.360'], ['N03.219.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.349.550'], ['Z01.542.846']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 |
Proximal and distal motor nerve conduction velocities in Werdnig-Hoffmann disease. | Using the latencies of M and F responses, we assessed motor nerve conduction velocity along the entire course of the median and ulnar nerves from the spinal cord to the muscle in 14 patients with the less severe forms of Werdnig-Hoffmann disease. In these forms, the motor nerve conduction velocities were decreased sign... | ['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Male', 'Motor Neurons', 'Muscular Atrophy, Spinal', 'Neural Conduction', 'Spinal Muscular Atrophies of Childhood'] | 2,340,034 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.675.655.500', 'A11.671.655.500'], ['C10.228.854.468', 'C10.574.562.500', 'C10.668.467.500'], ['G07.265.753', 'G11.561.601'], ['C10.228.854.468.800', 'C10.574.500.812', 'C10.574.562.500.750', '... | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neonatal assessment using the Apgar fuzzy expert system. | We applied fuzzy theory to the Apgar scoring system (APG) to devise an Apgar fuzzy expert system (AFES). Three AFESs were determined separately by each one of three doctor groups (four inexperienced obstetricians, four experienced obstetricians and four expert neonatologists) in order to demonstrate that the AFES refle... | ['Acidosis', 'Apgar Score', 'Asphyxia Neonatorum', 'Diagnosis, Computer-Assisted', 'Expert Systems', 'Fuzzy Logic', 'Humans', 'Infant, Newborn', 'Microcomputers', 'Neonatology', 'Sensitivity and Specificity', 'User-Computer Interface'] | 7,924,262 | [['C18.452.076.176'], ['E01.370.600.050'], ['C16.614.092'], ['E01.158', 'L01.313.500.750.100.158'], ['L01.224.050.375.190'], ['E05.599.250', 'K01.752.448.250', 'L01.224.050.375.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['L01.224.230.260.550'], ['H02.403.670.400'], ['E05.318.370.800', ... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Humanities [K]', 'Organisms [B]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
Cytologic features of deep juvenile xanthogranuloma. | Juvenile xanthogranuloma (JXG) is a rare lesion of the skin and deep tissues whose cytologic features have not previously been published. We report on 2 cases of JXG in patients aged 5 days and 5 yr who presented with an axillary mass and enlarged supraclavicular lymph node, respectively. Fine-needle aspiration and tou... | ['Axilla', 'Biopsy, Needle', 'Child, Preschool', 'Diagnosis, Differential', 'Humans', 'Infant, Newborn', 'Lymph Nodes', 'Xanthogranuloma, Juvenile'] | 8,982,590 | [['A01.378.800.090'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['M01.060.406.448'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['A10.54... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Relationships between mitochondrial function and metabolic flexibility in type 2 diabetes mellitus. | INTRODUCTION: Mitochondrial dysfunction, lipid accumulation, insulin resistance and metabolic inflexibility have been implicated in the etiology of type 2 diabetes (T2D), yet their interrelationship remains speculative. We investigated these interrelationships in a group of T2D and obese normoglycemic control subjects.... | ['Aged', 'Blood Glucose', 'Diabetes Mellitus, Type 2', 'Fatty Acids, Nonesterified', 'Glucose Clamp Technique', 'Humans', 'Insulin', 'Insulin Resistance', 'Lipid Metabolism', 'Male', 'Middle Aged', 'Mitochondria', 'Muscle, Skeletal', 'Obesity'] | 23,418,416 | [['M01.060.116.100'], ['D09.947.875.359.448.500'], ['C18.452.394.750.149', 'C19.246.300'], ['D10.251.310'], ['E01.370.225.124.100.350', 'E05.196.500', 'E05.200.124.100.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['C18.452.394.968.500', 'G07.690... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An objective technique to measure the depth-of-focus in free space. | BACKGROUND: Determining the depth-of-focus (DOF) objectively in free space is important, as this provides information regarding the range of clear vision under more natural viewing conditions in which target blur, size, and proximal information, as well as other monocular depth cues, are present.METHODS: The DOF was as... | ['Accommodation, Ocular', 'Adult', 'Depth Perception', 'Diagnostic Techniques, Ophthalmological', 'Humans', 'Hyperopia', 'Myopia', 'Space Perception'] | 16,362,316 | [['G14.010'], ['M01.060.116'], ['F02.463.593.200', 'F02.463.593.778.255'], ['E01.370.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C11.744.479'], ['C11.744.636'], ['F02.463.593.778']] | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
MATS: a Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data. | Ultra-deep RNA sequencing has become a powerful approach for genome-wide analysis of pre-mRNA alternative splicing. We develop MATS (multivariate analysis of transcript splicing), a bayesian statistical framework for flexible hypothesis testing of differential alternative splicing patterns on RNA-Seq data. MATS uses a ... | ['Alternative Splicing', 'Bayes Theorem', 'Brain', 'Cell Line, Tumor', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Multivariate Analysis', 'RNA-Binding Proteins', 'Reverse Transcriptase Polymerase Chain Reaction', 'Sequence Analysis, RNA'] | 22,266,656 | [['G02.111.760.700.100', 'G03.839.700.100', 'G05.308.700.700.100'], ['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['A08.186.211'], ['A11.251.210.190', 'A11.251.860.180'], ['E05.393.760.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.150.500', 'N05.715.360.750.125.5... | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Androgen-deprivation therapy in treatment of prostate cancer and risk of myocardial infarction and stroke: a nationwide Danish population-based cohort study. | BACKGROUND: Androgen-deprivation therapy (ADT) has been suggested to increase the risk for cardiovascular diseases, including myocardial infarction (MI) and stroke, but data are inconsistent.OBJECTIVES: To investigate the association between ADT and risk for MI and stroke in Danish men with prostate cancer.DESIGN, SETT... | ['Aged', 'Androgen Antagonists', 'Cohort Studies', 'Denmark', 'Gonadotropin-Releasing Hormone', 'Humans', 'Male', 'Myocardial Infarction', 'Orchiectomy', 'Prostatic Neoplasms', 'Risk Assessment', 'Stroke'] | 23,433,805 | [['M01.060.116.100'], ['D06.347.065', 'D27.505.696.399.450.065'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['Z01.542.816.124'], ['D06.472.699.327.740.320', 'D12.644.400.400.740.320', 'D12.644.456.460', 'D12.644.548.365.740.320', 'D12.776.631.650.405.740.320'], ['B01.050.150.900.649... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Demonstration of an in vivo functional beta 3-adrenoceptor in man. | Although it is well established in several mammalian species that beta 3-adrenoceptors play a major role in regulating lipolysis and thermogenesis in adipose tissue, the functional existence and role of this receptor subtype in man has been controversial. We investigated whether the beta 3-adrenoceptor functionally co-... | ['Adipose Tissue', 'Adrenergic beta-Antagonists', 'Adult', 'Analysis of Variance', 'Animals', 'Body Temperature Regulation', 'Cells, Cultured', 'Dobutamine', 'Female', 'Humans', 'Isoproterenol', 'Kinetics', 'Lipolysis', 'Male', 'Mammals', 'Metoprolol', 'Microdialysis', 'Middle Aged', 'Propanolamines', 'Propranolol', 'R... | 7,738,189 | [['A10.165.114'], ['D27.505.519.625.050.200.200', 'D27.505.696.577.050.200.200'], ['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['A11.251'], ['D02.092.311.220', 'D02.092.471.683.410', 'D02.455.426.559.389.657.166.175.2... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Accurate Measurement of Residual Dipolar Couplings in Large RNAs by Variable Flip Angle NMR. | NMR approaches using nucleotide-specific deuterium labeling schemes have enabled structural studies of biologically relevant RNAs of increasing size and complexity. Although local structure is well-determined using these methods, definition of global structural features, including relative orientations of independent h... | ['Nuclear Magnetic Resonance, Biomolecular', 'Nucleic Acid Conformation', 'RNA'] | 29,757,635 | [['E05.196.867.519.550'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.444.735']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selective stimulation and differentiation of early antigens in lymphoblastoid cell lines producing Epstein-Barr-like viruses. | Comparisons of early antigens (EA) of EBV-related lymphotropic herpes virus of Old World primates have proved difficult to accomplish because antigen levels are low in infected cells and the ratio of virus capsid antigen to EA is generally high. To overcome these difficulties, we have developed a procedure which combin... | ['Animals', 'Antibodies, Viral', 'Antigens, Viral', 'Cell Line', 'Epitopes', 'Haplorhini', 'Herpesviridae', 'Herpesvirus 4, Human', 'Hominidae', 'Humans', 'Idoxuridine', 'Papio', 'Phosphonoacetic Acid'] | 82,609 | [['B01.050'], ['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D23.050.327'], ['A11.251.210'], ['D23.050.550'], ['B01.050.150.900.649.313.988.400'], ['B04.280.382'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['B01.050.150.900.649.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Esophageal abscess complicating endoscopic treatment of refractory gastroesophageal reflux disease by Enteryx injection: a first case report. | Enteryx (Boston Scientific) is an injectable solution containing 8% ethylene vinyl alcohol copolymer dissolved in dimethyl sulfoxide that has been approved for the treatment of gastroesophageal reflux disease (GERD). The technique consists of injecting Enteryx into the lower esophageal sphincter where it solidifies int... | ['Abscess', 'Anti-Bacterial Agents', 'Disease Progression', 'Drug Therapy, Combination', 'Esophageal Diseases', 'Esophagogastric Junction', 'Esophagoscopy', 'Fatal Outcome', 'Female', 'Gastroesophageal Reflux', 'Humans', 'Injections, Intralesional', 'Middle Aged', 'Polyvinyls', 'Severity of Illness Index'] | 15,330,928 | [['C01.830.025', 'C23.550.470.756.100'], ['D27.505.954.122.085'], ['C23.550.291.656'], ['E02.319.310'], ['C06.405.117'], ['A03.556.875.500.414', 'A03.556.875.875.330'], ['E01.370.372.250.250.275', 'E01.370.388.250.250.250.260', 'E04.210.240.250.260', 'E04.502.250.250.250.260'], ['E05.318.308.985.550.325', 'N01.224.935.... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Effect of automatic cluster remover settings on production, udder health, and milking duration. | This study evaluated the effect of 4 criteria for determining the end-point of milking on milk yield, milk composition, completeness of milking-out, teat skin condition, somatic cell count (SCC), and the incidence of clinical mastitis (CM) in pasture-based dairy cows milked over 35 wk. The objective was to reduce milki... | ['Animals', 'Cattle', 'Dairying', 'Fats', 'Female', 'Lactation', 'Lactose', 'Mammary Glands, Animal', 'Mastitis, Bovine', 'Milk', 'Milk Proteins'] | 20,494,162 | [['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['J01.040.246'], ['D10.212'], ['G08.686.523', 'G08.686.702.500'], ['D09.698.629.305.340', 'D09.947.750.340'], ['A10.336.482', 'A13.589'], ['C22.196.581'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525'], ['A12.... | ['Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Interaction of sirolimus and everolimus with hepatic and intestinal organic anion-transporting polypeptide transporters. | The goal of this study was to assess the interaction of the mTOR inhibitors (ImTORs) sirolimus and everolimus with the human organic anion-transporting polypeptides (OATPs) expressed in hepatocytes and enterocytes by conducting uptake experiments using (i) transfected HEK293T cells, (ii) the hepatocyte-like HepaRG cell... | ['Caco-2 Cells', 'Cyclosporine', 'Dose-Response Relationship, Drug', 'Drug Interactions', 'Everolimus', 'HEK293 Cells', 'Humans', 'Immunosuppressive Agents', 'Inhibitory Concentration 50', 'Intestinal Mucosa', 'Intestines', 'Liver', 'Organic Anion Transporters', 'Probenecid', 'Sirolimus', 'Transfection'] | 21,524,191 | [['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['D04.345.566.235.300', 'D12.644.641.235.300'], ['G07.690.773.875', 'G07.690.936.500'], ['G07.690.773.968'], ['D02.540.505.760.500'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.477.656'], ['E05.94... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Surgical palliation of truncus arteriosus with mitral atresia and hypoplastic left ventricle. | A rare case of truncus arteriosus associated with mitral valve atresia, hypoplastic left ventricle, and intact ventricular septum is reported. Successful medical management and surgical palliation of this defect is described. The possible embryology, pertinent hemodynamics, and clinical concerns with this unusual case ... | ['Female', 'Heart Ventricles', 'Humans', 'Infant, Newborn', 'Mitral Valve', 'Palliative Care', 'Truncus Arteriosus, Persistent'] | 9,456,135 | [['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['A07.541.510.507'], ['E02.760.666', 'N02.421.585.666'], ['C14.240.400.560.098.500', 'C14.280.400.560.098.500', 'C16.131.240.400.560.098.500']] | ['Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Marchiafava-Bignami disease with haemophagocytic lymphohistiocytosis as a postoperative complication of cardiac surgery. | Marchiafava-Bignami disease (MBD) is a rare complication of chronic alcoholism; however, MBD in a non-alcoholic diabetic patient has rarely been reported. The aetiology or pathophysiology of MBD is still unknown. A 50-year-old man with a history of untreated diabetes mellitus underwent on-pump beating coronary artery b... | ['Autopsy', 'Brain', 'Coronary Artery Bypass, Off-Pump', 'Coronary Artery Disease', 'Corpus Callosum', 'Fatal Outcome', 'Humans', 'Lymphohistiocytosis, Hemophagocytic', 'Magnetic Resonance Imaging', 'Male', 'Marchiafava-Bignami Disease', 'Middle Aged', 'Postoperative Complications'] | 31,451,466 | [['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['A08.186.211'], ['E04.100.376.719.332.199', 'E04.100.814.868.750.199', 'E04.928.220.520.220.189'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['A08.186.211.200.885.800.750'], ['E05.318.308.985.550.325', 'N01.224.935.698.201', 'N06.850.505.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
NMDA and AMPA receptor expression and cortical neuronal death are associated with p38 in glutamate-induced excitotoxicity in vivo. | Early overstimulation of ionotropic glutamate receptors (iGluRs), such as the N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) receptors, produces excitotoxicity in several brain regions. The molecular composition of those receptors and their regulation by intracellular signal... | ['Activating Transcription Factor 2', 'Age Factors', 'Analysis of Variance', 'Animals', 'Animals, Newborn', 'Carrier Proteins', 'Cell Death', 'Cell Survival', 'Cerebral Cortex', 'Cyclic AMP Response Element-Binding Protein', 'Densitometry', 'Drug Interactions', 'Enzyme Inhibitors', 'Female', 'Gene Expression Regulation... | 15,139,026 | [['D12.776.260.108.061.750', 'D12.776.930.127.061.750'], ['N05.715.350.075', 'N06.850.490.250'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['B01.050.050.282'], ['D12.776.157'], ['G04.146'], ['G04.346'], ['A08.186.211.200.885.287.500'], ['D12.776.260.108.184', 'D12.776.930.127.184']... | ['Chemicals and Drugs [D]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Nasal cylindrical cell papilloma. | Inverted papilloma is the most common benign tumor of nose and paranasal sinuses arising from lateral nasal wall and middle meatus. Histologically these tumors are composed of epithelial nests that are inverted, exophytic and cylindrical. Here we describe a clinical case of nasal cylindrical cell papilloma, which was t... | ['Female', 'Humans', 'Middle Aged', 'Nose Neoplasms', 'Papilloma'] | 16,250,292 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.149.721.600', 'C04.588.443.665.650', 'C05.116.231.754.600', 'C08.460.669', 'C08.785.600', 'C09.603.669', 'C09.647.685'], ['C04.557.470.700.600']] | ['Organisms [B]', 'Named Groups [M]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Evaluation of retinal function after photodynamic therapy of subfoveal choroidal neovascularisation in patients with age-related macular degeneration]. | INTRODUCTION: The aim of our study was to evaluate the visual acuity, visual field, retinal bioelectrical function and fluorescein angiography results in patients with subfoveal choroidal neovascularisation treated with photodynamic therapy (PDT).MATERIAL AND METHODS: Visual acuity (Snellen chart), static perimetry (PS... | ['Aged', 'Choroidal Neovascularization', 'Electric Impedance', 'Female', 'Fluorescein Angiography', 'Humans', 'Macula Lutea', 'Macular Degeneration', 'Male', 'Photochemotherapy', 'Visual Acuity', 'Visual Field Tests', 'Visual Fields'] | 19,425,475 | [['M01.060.116.100'], ['C11.941.160.244', 'C23.550.589.500.145'], ['G01.358.500.249.277.350'], ['E01.370.370.050.350', 'E01.370.380.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A09.371.729.522'], ['C11.768.585.439'], ['E02.186.500', 'E02.319.685', 'E02.774.722'], ['E01.370.380.850.950', 'F02.463.593.932.90... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Simultaneous targeting of Requiem & Alg-2 in Chinese hamster ovary cells for improved recombinant protein production. | Apoptosis is known to be the main cause of cell death in the bioreactor environment, leading to the loss of recombinant protein productivity. In a previous study, transcriptional profiling was used to identify and target four early apoptosis-signaling genes: FADD, FAIM, Alg-2, and Requiem. The resulting cell lines had ... | ['Animals', 'Apoptosis Regulatory Proteins', 'Base Sequence', 'CHO Cells', 'Calcium-Binding Proteins', 'Caspases', 'Cricetinae', 'Cricetulus', 'DNA Primers', 'DNA-Binding Proteins', 'Hydrolysis', 'Interferon-gamma', 'Polymerase Chain Reaction', 'Recombinant Proteins', 'Transcription Factors'] | 20,571,937 | [['B01.050'], ['D12.644.360.075', 'D12.776.476.075'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210.200', 'A11.436.155'], ['D12.776.157.125'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['B01.050.150.900.649.313.992.635.075.25... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Acute Brachial Radiculoplexopathy and Giant Cell Arteritis. | INTRODUCTION: Giant cell arteritis (GCA), a vasculitis involving large-sized and medium-sized vessels (which most commonly involves temporal arteries), is easily recognized in older patients presenting with headache, scalp tenderness, and raised inflammatory markers. Neurological complications (either central or periph... | ['Acute Disease', 'Aged, 80 and over', 'Brachial Plexus Neuropathies', 'Female', 'Giant Cell Arteritis', 'Humans', 'Radiculopathy'] | 29,266,041 | [['C23.550.291.125'], ['M01.060.116.100.080'], ['C10.668.829.100'], ['C10.114.875.700', 'C10.228.140.300.850.500', 'C14.907.253.946.700', 'C14.907.940.090.530', 'C14.907.940.907.700', 'C17.800.862.252', 'C20.111.258.962.800'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.668.829.820']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Duration of lactation, endocrine and metabolic state, and fertility of primiparous sows. | The objectives of this study were to determine factors affecting the reproductive performance of primiparous sows early weaned (EW; n = 35) at d 14 or conventionally weaned (CW; n = 35) at d 24 of lactation. Sow BW and backfat were recorded at farrowing, weekly until weaning, and at standing heat. Feed intake was contr... | ['Adipose Tissue', 'Animals', 'Body Weight', 'Estradiol', 'Female', 'Fertility', 'Follicle Stimulating Hormone', 'Insulin-Like Growth Factor I', 'Lactation', 'Luteinizing Hormone', 'Ovulation', 'Pregnancy', 'Pregnancy, Animal', 'Swine', 'Time Factors', 'Weaning'] | 12,926,791 | [['A10.165.114'], ['B01.050'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G08.686.210'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['D12.64... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Fluorescein, indocyanine green and optical coherence tomography angiography in patients with native exudative age-related macular degeneration]. | INTRODUCTION: The newly developed optical coherence tomography angiography (OCT-A) has provided new means to depict the vascular plexus in neovascular age-related macular degeneration (nAMD). If these images are to be used as a basis for therapeutic decisions, it is of vital importance to classify choroidal neovascular... | ['Choroidal Neovascularization', 'Fluorescein', 'Fluorescein Angiography', 'Humans', 'Indocyanine Green', 'Macular Degeneration', 'Tomography, Optical Coherence'] | 28,707,091 | [['C11.941.160.244', 'C23.550.589.500.145'], ['D02.455.426.779.347.390', 'D03.633.300.953.275.390', 'D04.711.347.390'], ['E01.370.370.050.350', 'E01.370.380.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.473.400'], ['C11.768.585.439'], ['E01.370.350.589.249.500', 'E01.370.350.825.805.500', 'E05.6... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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