Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Antinociceptive activity of deltorphin analogs in the formalin test. | Two deltorphin (DLT: Tyr-D-Met-Phe-His-Leu-Met-Asp-NH2) analogs, [N alpha-n-butyl-Gly6]DLT ([nBuG6]DLT) and [N alpha-iso-butyl-Gly6]DLT ([isoBuG6]DLT), were examined for their antinociceptive activities by a formalin test in mice after subcutaneous (s.c.) injection. [nBuG6]DLT exhibited potent dose-dependent antinocice... | ['Analgesics, Opioid', 'Animals', 'Formaldehyde', 'Male', 'Mice', 'Oligopeptides', 'Receptors, Opioid, delta'] | 8,890,946 | [['D27.505.696.277.600.500', 'D27.505.696.663.850.014.760.500', 'D27.505.954.427.040.550.500', 'D27.505.954.427.210.600.500'], ['B01.050'], ['D02.047.407'], ['B01.050.150.900.649.313.992.635.505.500'], ['D12.644.456'], ['D12.776.543.750.695.620.200', 'D12.776.543.750.720.600.610.200', 'D12.776.543.750.750.555.610.200']... | ['Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Selective loss of binding sites for the iodinated alpha-neurotoxin I from Naja mossambica mossambica venom upon enzymatic deglycosylation of Torpedo electric organ membranes. | Removal of asparagine-linked carbohydrate chains from Torpedo marmorata electric organ membranes was found to inhibit the binding of the iodinated alpha-neurotoxin I from Naja mossambica mossambica snake venom to its receptor. Optimal deglycosylation of membranes by endoglycosidase F resulted in a 55% inhibition of alp... | ['Animals', 'Asparagine', 'Binding Sites', 'Binding, Competitive', 'Cobra Neurotoxin Proteins', 'Concanavalin A', 'Elapid Venoms', 'Electric Organ', 'Glycoside Hydrolases', 'Glycosylation', 'Kinetics', 'Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase', 'Membrane Proteins', 'Receptors, Cholinergic', 'Torpedo'] | 3,134,197 | [['B01.050'], ['D12.125.068.060', 'D12.125.095.165', 'D12.125.154.049'], ['G02.111.570.120'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D12.776.831.244', 'D20.888.850.325.200', 'D23.946.833.850.325.200'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['D20.888.850.325', 'D23.946.833.850.325'], ['A13.33... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genetic determinants of host-specificity in bipartite geminivirus DNA A components. | Geminiviruses are small, ssDNA-containing plant viruses. Bean golden mosaic virus (BGMV) and tomato golden mosaic virus (TGMV) have bipartite genomes, the components of which are designated A and B. Although they are closely related, BGMV and TGMV nevertheless exhibit distinct host-specific phenotypes, with BGMV being ... | ['Capsid', 'DNA, Plant', 'DNA, Viral', 'Fabaceae', 'Geminiviridae', 'Mosaic Viruses', 'Open Reading Frames', 'Phenotype', 'Plants, Medicinal', 'Plants, Toxic', 'Tobacco'] | 9,837,800 | [['A21.249.500.250'], ['D13.444.308.435'], ['D13.444.308.568'], ['B01.650.940.800.575.912.250.401'], ['B04.280.350', 'B04.715.270'], ['B04.715.464'], ['G05.360.335.760.640', 'G05.360.340.024.340.137.650'], ['G05.695'], ['B01.650.560'], ['B01.650.660'], ['B01.650.940.800.575.912.250.908.500.900']] | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Beyond the lesion: the epileptogenic networks around cavernous angiomas. | The relationship between epileptogenic lesions and the extension of epileptogenicity is a major challenge in presurgical evaluation of drug resistant epilepsies. In this study, we aimed at quantifying the epileptogenic properties of brain structures explored by depth electrodes in patients investigated by stereoelectro... | ['Adult', 'Brain', 'Brain Mapping', 'Brain Neoplasms', 'Electroencephalography', 'Epilepsies, Partial', 'Female', 'Hemangioma, Cavernous, Central Nervous System', 'Humans', 'Male', 'Middle Aged', 'Nerve Net', 'Young Adult'] | 24,661,427 | [['M01.060.116'], ['A08.186.211'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490.360'], ['C04.557.645.375.385.500', 'C10.500.190.200', 'C14.240.850.875.249', 'C14.907.454... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Pancreatic mass of unusual etiology: case report of metastatic disease after a prolonged lag phase. | Although not a typical site, the pancreas does occasionally harbor metastatic disease. Management of these metastases differs from the management of conventional primary cancers. Our case is one of an 85-year-old female presenting with obstructive jaundice and whose workup revealed a pancreatic mass. Her past medical h... | ['Abdominal Pain', 'Aged', 'Aged, 80 and over', 'Biopsy, Needle', 'Breast Neoplasms', 'Carcinoma, Ductal, Breast', 'Cholangiopancreatography, Endoscopic Retrograde', 'Female', 'Follow-Up Studies', 'Humans', 'Immunohistochemistry', 'Jaundice', 'Mastectomy', 'Neoplasm Staging', 'Pancreatectomy', 'Pancreatic Neoplasms', '... | 16,447,487 | [['C23.888.592.612.054', 'C23.888.821.030'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['C04.588.180', 'C17.800.090.500'], ['C04.5... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Biomechanics of patellar tendon autograft for reconstruction of the anterior cruciate ligament in the goat: three-year study. | This study examined the biomechanics of anterior cruciate ligament-patellar tendon autografts for as long as 3 years after surgery. Twenty-seven adult female goats were tested; four served as controls and the others received an autograft to the right knee with each left knee serving as an additional control. The animal... | ['Animals', 'Anterior Cruciate Ligament', 'Biomechanical Phenomena', 'Elasticity', 'Female', 'Goats', 'Joint Instability', 'Knee Joint', 'Longitudinal Studies', 'Patella', 'Postoperative Complications', 'Tendons', 'Transplantation, Autologous', 'Viscosity', 'Weight-Bearing'] | 7,674,076 | [['B01.050'], ['A02.513.514.100', 'A02.835.583.512.100', 'A10.165.669.514.100'], ['G01.154.090', 'G01.374.089'], ['G01.374.590'], ['B01.050.150.900.649.313.500.380.513'], ['C05.550.521'], ['A02.835.583.475'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['A02.835.232.043.65... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
[Prevention of overweight and obesity in the workplace. BASF-health promotion campaign "trim down the pounds--losing weight without losing your mind"]. | BACKGROUND: The rise in the prevalence of overweight and obesity and their associated diseases is leading to substantial health and socio-economic problems in industrialized countries. The Commission of the European Community indicates that workplaces are a setting that has a strong potential for health promotion and d... | ['Adult', 'Aged', 'Body Mass Index', 'Female', 'Germany', 'Health Promotion', 'Humans', 'Male', 'Middle Aged', 'Obesity', 'Occupational Health', 'Overweight', 'Prevalence', 'Program Evaluation', 'Treatment Outcome'] | 17,701,837 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['Z01.542.315'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Intestinal adaptation after jejuno-ileal bypass operation for massive obesity. | Intestinal adaptation was studied in six patients with massive obesity treated by jejuno-ileal bypass operation. Glucose absorption in the jejunum was measured by a perfusion technique. The morphometric and enzymatic measurements were carried out on biopsies from the proximal jejunum and the distal ileum. Results obtai... | ['Adaptation, Physiological', 'Galactosidases', 'Glucose', 'Humans', 'Hyperplasia', 'Ileum', 'Intestinal Absorption', 'Intestinal Mucosa', 'Jejunum', 'Obesity', 'Sucrase'] | 976,297 | [['G07.025', 'G16.012.500'], ['D08.811.277.450.410'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.444'], ['A03.556.124.684.249', 'A03.556.249.124'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500', 'G07.690.725.015.500.374.500', 'G10.261.353.500'], ['A03.... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Disability and factors associated with gestational low back pain]. | PURPOSE: To determine the prevalence of low back pain in pregnant women and to describe its characteristics and associated factors.METHODS: The participants were 269 pregnant women in the first to the third trimester of pregnancy, seen at the obstetrics outpatient clinic of a University Hospital in the Brazilian Northe... | ['Adolescent', 'Adult', 'Cross-Sectional Studies', 'Disability Evaluation', 'Female', 'Humans', 'Low Back Pain', 'Pain Measurement', 'Pregnancy', 'Pregnancy Complications', 'Prevalence', 'Surveys and Questionnaires', 'Young Adult'] | 24,500,508 | [['M01.060.057'], ['M01.060.116'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.592.612.107.400'], ['E01.370.600.550.324'], ['G08.686.784.769'], ['C13.703'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', '... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Combined cognitive-behavioral, psychopharmacological and nutritional therapy in bulimia nervosa. | Fifteen women with bulimia nervosa were treated with a 4-month course of combined cognitive-behavioral, nutritional and antidepressant therapy (5 with amineptine and 10 with fluvoxamine). Patients were monitored before and after 1, 2 and 4 months of therapy for body mass index (BMI), for eating disorder symptoms by the... | ['Adolescent', 'Adult', 'Antidepressive Agents, Second-Generation', 'Antidepressive Agents, Tricyclic', 'Behavior Therapy', 'Body Weight', 'Bulimia', 'Cognitive Behavioral Therapy', 'Combined Modality Therapy', 'Dibenzocycloheptenes', 'Female', 'Fluvoxamine', 'Humans', 'Nutritional Physiological Phenomena', 'Psychiatri... | 7,477,802 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.427.700.122.050'], ['D27.505.954.427.700.122.055'], ['F04.754.137'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C23.888.821.645.500'], ['F04.754.137.350'], ['E02.186'], ['D02.455.426.559.847.181.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Diagnostic and therapeutic technology assessment. Angelchik antireflux prosthesis. | In summary, the DATTA panelists felt that the Angelchik prosthesis is effective in relieving gastroesophageal reflux and that the device, along with other types of surgical procedures, is indicated when medical management has failed and when objective evidence of incompetence of the lower esophageal sphincter is presen... | ['American Medical Association', 'Gastroesophageal Reflux', 'Humans', 'Prostheses and Implants', 'Technology Assessment, Biomedical', 'United States'] | 3,747,052 | [['N03.540.828.589.274'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695'], ['N03.880', 'N05.715.360.825'], ['Z01.107.567.875']] | ['Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Median and tibial nerve somatosensory evoked potentials: middle-latency components from the vicinity of the secondary somatosensory cortex in humans. | The topography of the middle-latency N110 after radial nerve stimulation suggested a generator in SII. To support this hypothesis, we have tried to identify a homologous component in the tibial nerve SEP (somatosensory evoked potential). Evoked potentials following tibial nerve stimulation (motor + sensory threshold) w... | ['Adult', 'Electroencephalography', 'Evoked Potentials, Somatosensory', 'Female', 'Humans', 'Male', 'Median Nerve', 'Somatosensory Cortex', 'Tibial Nerve'] | 9,344,076 | [['M01.060.116'], ['E01.370.376.300', 'E01.370.405.245'], ['G07.265.216.500.400', 'G11.561.200.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800.720.050.500'], ['A08.186.211.200.885.287.500.670.675', 'A08.186.211.200.885.287.500.814.906'], ['A08.800.800.720.450.760.820']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Ultrasound diagnosis of pancreatic disease. | The gray-scale ultrasound features of the normal and pathological pancreas are presented in 37 patients, 25 of whom presented with jaundice, and 12 of whom had abdominal pain suspected to be of pancreatic origin. The ultrasound criteria for the diagnosis of pancreatic carcinomata, acute pancreatitis and pancreatic pseu... | ['Humans', 'Pancreatic Diseases', 'Pancreatic Neoplasms', 'Ultrasonography'] | 286,915 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Quantity versus quality of gait and quality of life in patients with osteoarthritis. | PURPOSE: This study investigated the relationship between the quality of life, quality of gait and the quantity of gait in patients with impairments in the lower extremities.METHODS: Twenty-six subjects (age 58.6+/-13.4 years) suffering from knee or hip osteoarthritis were investigated before implantation of an endopro... | ['Gait', 'Humans', 'Middle Aged', 'Osteoarthritis, Hip', 'Osteoarthritis, Knee', 'Quality of Life'] | 18,054,233 | [['E01.370.600.250', 'G11.427.410.568.900.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.550.114.606.400', 'C05.799.613.400'], ['C05.550.114.606.500', 'C05.799.613.500'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[Correlations between hemoglobin A1 and other metabolic and clinical parameters in insulin-dependent diabetics followed in ambulatory care]. | 210 HbA1 percentage tests were determined in 52 ambulatory insulinodependent patients. There was a close correlation between HbA1 and blood-glucose of the previous two months: mean post-prandial, mean daily and, less strongly, mean fasting blood-glucose. The level of glycosylated haemoglobins correlated significantly w... | ['Adolescent', 'Adult', 'Aged', 'Blood Glucose', 'Child', 'Cholesterol', 'Cholesterol, HDL', 'Diabetes Mellitus', 'Female', 'Glycated Hemoglobin A', 'Glycosuria', 'Humans', 'Lipids', 'Lipoproteins, HDL', 'Male', 'Middle Aged', 'Triglycerides', 'Uric Acid'] | 7,110,604 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['D09.947.875.359.448.500'], ['M01.060.406'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['C18.452.394.750', 'C19.246'], ['D09.400.430... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of denervation on cell-to-cell communication between acinar cells of rat submandibular salivary gland. | Communication measured by electrical cell coupling and dye transfer decreased transiently 1 day after parasympathectomy and then recovered 2 days later. Parasympathectomy decreased communication again 2 weeks later, coinciding with a decrease in the wet weight of the gland, but sympathectomy did not affect it. Thus par... | ['Animals', 'Cell Communication', 'Denervation', 'Male', 'Parasympathetic Nervous System', 'Rats', 'Rats, Inbred Strains', 'Submandibular Gland', 'Sympathectomy'] | 3,479,073 | [['B01.050'], ['G04.085'], ['E04.525.210'], ['A08.800.050.600'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['A03.556.500.760.812', 'A10.336.779.812', 'A14.549.760.812'], ['E04.525.210.105.800']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Integration biases in the Ouchi and other visual illusions. | A texture pattern devised by the Japanese artist H Ouchi has attracted wide attention because of the striking appearance of relative motion it evokes. The illusion has been the subject of several recent empirical studies. A new account is presented, along with a simple experimental test, that attributes the illusion to... | ['Bayes Theorem', 'Humans', 'Motion Perception', 'Optical Illusions', 'Visual Pathways'] | 11,040,954 | [['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.932.567'], ['F02.463.593.446.659'], ['A08.612.220.860']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Implementing right-to-know legislation for health care workers in Manitoba: a bipartite sectoral train-the-trainer approach. | In October 1988, right-to-know legislation was introduced in Canada. This presented a technical and administrative challenge to the health care sector. With over 170 health care facilities in Manitoba to be brought into compliance, some large, some small, some rural, some urban, a cooperative approach was needed. A lab... | ['Evaluation Studies as Topic', 'Hazardous Substances', 'Health Personnel', 'Humans', 'Inservice Training', 'Labor Unions', 'Manitoba', 'Occupational Health', 'Teaching'] | 1,442,802 | [['E05.337', 'N05.715.360.335'], ['D27.888.426'], ['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I02.574'], ['N03.540.571'], ['Z01.107.567.176.410'], ['N01.400.525'], ['I02.903']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Enhancing effect of menthol on nicotine self-administration in rats. | RATIONALE: Tobacco smoking is a leading preventable cause of premature death in the USA. Menthol is a significant flavoring additive in tobacco products. Clinical evidence suggests that menthol may promote tobacco smoking and nicotine dependence. However, it is unclear whether menthol enhances the reinforcing actions o... | ['Animals', 'Behavior, Animal', 'Conditioning, Operant', 'Dose-Response Relationship, Drug', 'Male', 'Menthol', 'Nicotine', 'Nicotinic Agonists', 'Rats', 'Rats, Sprague-Dawley', 'Reinforcement, Psychology', 'Self Administration', 'Tobacco Smoking', 'Tobacco Use Disorder'] | 27,473,365 | [['B01.050'], ['F01.145.113'], ['F02.463.425.179.509'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.033.415.510.500.605', 'D02.455.426.392.368.367.211.750', 'D02.455.849.575.157.500', 'D10.289.510.500.605'], ['D03.132.760.570', 'D03.383.725.518'], ['D27.505.519.625.120.140.700', 'D27.505.696.577.120.140.700'], ['B01.... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of host genetics and environmental conditions on fecal microbiota composition of pigs. | Since microbiota may influence the physiology of its host including body weight increase, growth rate or feed intake, in this study we determined the microbiota composition in high or low residual feed intake (HRFI and LRFI) pig lines, of different age and/or subjected to sanitary stress by sequencing the V3/V4 variabl... | ['Age Factors', 'Animals', 'Diet', 'Eating', 'Environment', 'Feces', 'Gastrointestinal Microbiome', 'RNA, Bacterial', 'RNA, Ribosomal, 16S', 'Species Specificity', 'Stress, Physiological', 'Sus scrofa', 'Weaning'] | 30,086,169 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['G07.203.650.240'], ['G07.203.650.283', 'G10.261.330'], ['G16.500.275', 'N06.230'], ['A12.459'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['D13.444.735.473'], ['D13.444.735.686.670'], ['G16.824'], ['G07.775'], ['B01.050.150... | ['Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Increased Gamma Brainwave Amplitude Compared to Control in Three Different Meditation Traditions. | Despite decades of research, effects of different types of meditation on electroencephalographic (EEG) activity are still being defined. We compared practitioners of three different meditation traditions (Vipassana, Himalayan Yoga and Isha Shoonya) with a control group during a meditative and instructed mind-wandering ... | ['Adult', 'Alpha Rhythm', 'Artifacts', 'Attention', 'Awareness', 'Cerebral Cortex', 'Eye Movements', 'Female', 'Gamma Rhythm', 'Humans', 'India', 'Male', 'Meditation', 'Middle Aged', 'Muscle Contraction', 'Psychometrics', 'Respiration', 'Sensation', 'Signal Processing, Computer-Assisted', 'Spectrum Analysis', 'Yoga'] | 28,118,405 | [['M01.060.116'], ['E01.370.376.300.150.374', 'E01.370.405.245.287.374', 'G07.265.087.500', 'G11.561.127.500'], ['E05.047'], ['F02.830.104.214'], ['F02.463.188.150'], ['A08.186.211.200.885.287.500'], ['G11.427.410.140', 'G14.350'], ['E01.370.376.300.150.906', 'E01.370.405.245.287.906', 'G07.265.087.906', 'G11.561.127.9... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Organisms [B]', 'Geographicals [Z]', 'Information Science [L]', 'Humanities [K]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Direct stochastic simulation of Ca2+ motion in Xenopus eggs. | The release of important intracellular ions has been widely modeled using two approaches, namely, (1) Fickian diffusion, in which sometimes tensorial diffusion coefficients are used to fit observed temporally varying concentrations of calcium, and (2) cellular automata, which produce a set of localized finite differenc... | ['Animals', 'Calcium', 'Calcium Channels', 'Calcium Signaling', 'Cell Membrane', 'Cells, Cultured', 'Computer Simulation', 'Diffusion', 'Ion Channel Gating', 'Membrane Potentials', 'Models, Biological', 'Models, Chemical', 'Models, Statistical', 'Oocytes', 'Stochastic Processes', 'Xenopus laevis'] | 16,196,610 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['A11.284.149'], ['A11.251'], ['L01.224.160'], ['G01.202', 'G02.196'], ['G02.111.820.400', 'G04.835.400',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Pulmonary nodules in a newborn with ATP-binding cassette transporter A3 (ABCA3) mutations. | Mutations in the gene for adenosine triphosphate-binding cassette transporter A3 (ABCA3) have been reported in infants and children with fatal surfactant deficiency and interstitial lung disease. Previously reported radiographic lung findings include ground-glass opacification, streaky infiltrates, and interstitial sep... | ['ATP-Binding Cassette Transporters', 'Autopsy', 'Biopsy, Needle', 'Disease Progression', 'Fatal Outcome', 'Female', 'Gene Expression Regulation, Neoplastic', 'High-Frequency Ventilation', 'Humans', 'Immunohistochemistry', 'Infant, Newborn', 'Lung Neoplasms', 'Mutation', 'Radiography, Thoracic', 'Respiratory Distress S... | 21,464,189 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Named Groups [M]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Improvement of erectile function with Prelox: a randomized, double-blind, placebo-controlled, crossover trial. | In a randomly allocated, double-blind, placebo-controlled, crossover design, 50 patients with mild to moderate erectile dysfunction (ED) were treated for 1 month with placebo or a combination of L-arginine aspartate and Pycnogenol (Prelox). Patients reported sexual function from diaries. Testosterone levels and endothe... | ['Adult', 'Arginine', 'Aspartic Acid', 'Blood Pressure', 'Cholesterol', 'Cross-Over Studies', 'Double-Blind Method', 'Drug Combinations', 'Drug Therapy, Combination', 'Erectile Dysfunction', 'Flavonoids', 'Humans', 'Male', 'Middle Aged', 'Neurotransmitter Agents', 'Nitric Oxide Synthase', 'Penile Erection', 'Plant Extr... | 17,703,218 | [['M01.060.116'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['D12.125.067.500', 'D12.125.119.170', 'D12.125.427.040'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ternary thiol-ene photopolymerization for facile preparation of ionic liquid-functionalized hybrid monolithic columns based on polyhedral oligomeric silsesquioxanes. | A simple thiol-ene photopolymerization approach was developed for the rapid preparation of ionic liquid-functionalized hybrid monolithic column based on polyhedral oligomeric silsesquioxane (POSS). "One-pot" polymerization was realized in the UV-transparent fused-silica capillary by using octanethiol, 1-allyl-3-methyli... | ['Capillary Electrochromatography', 'Chemistry Techniques, Analytical', 'Electroosmosis', 'Free Radicals', 'Hydrophobic and Hydrophilic Interactions', 'Ionic Liquids', 'Methacrylates', 'Organosilicon Compounds', 'Polymerization', 'Sulfhydryl Compounds', 'Vinyl Compounds'] | 30,929,865 | [['E05.196.181.400.150', 'E05.196.401.190.249', 'E05.301.300.190.500'], ['E05.196'], ['E05.196.385', 'E05.301.270', 'G01.154.090.750.500', 'G02.111.655.500', 'G02.691.250', 'G02.723.495.250'], ['D01.339', 'D02.389'], ['G02.409'], ['D27.720.844.500'], ['D02.241.081.069.600'], ['D02.756'], ['G02.750'], ['D02.886.489'], [... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Cation selective electroanalysis of K(+)-, Na(+)- and Ca2(+) concentrations in acetate dialysis solutions]. | An account is given on the influence of acetate ions in direct potentiometric analyses of dialytic solutions using K+, Na+ and Ca2+ selective carrier PVC solid contact sensors. By calibrating the flow-through membrane electrodes with anion-corrected solutions, the deviation of ion concentrations based on the acetate ef... | ['Acetates', 'Calcium', 'Dialysis Solutions', 'Electrodes', 'Humans', 'Potassium', 'Potentiometry', 'Renal Dialysis', 'Sodium'] | 2,031,988 | [['D02.241.081.018', 'D10.251.400.045'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D26.776.708.322', 'D27.505.954.578.483', 'D27.720.752.483'], ['E07.305.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.549.550', 'D01.268.557.575', 'D01.552.528.652', 'D01.552.547.650'], ['E05.196.922.750... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Research on the correlation of vascular endothelial growth factor and dendritic cell in patients with oral squamous cell carcinoma]. | OBJECTIVE: To investigate the effect of vascular endothelial growth factor (VEGF) on the differentiation, formation and function of the dendritic cell (DC) in peripheral blood of patients with oral squamous cell carcinoma (OSCC).METHODS: Flow cytometry was used to detect the number of DC in peripheral blood of 81 patie... | ['Adult', 'Aged', 'Aged, 80 and over', 'Carcinoma, Squamous Cell', 'Cell Differentiation', 'Dendritic Cells', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mouth Neoplasms', 'Neoplasm Staging', 'Vascular Endothelial Growth Factor A'] | 19,576,015 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['G04.152'], ['A11.066.270', 'A11.436.270', 'A15.382.066.270', 'A15.382.670.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.588.443.591', 'C07.465.530'], ['E01.789.625'], ['... | ['Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Transcriptional regulation of the Drosophila melanogaster muscle myosin heavy-chain gene. | We show that a 2.6kb fragment of the muscle myosin heavy-chain gene (Mhc) of Drosophila melanogaster (containing 458 base pairs of upstream sequence, the first exon, the first intron and the beginning of the second exon) drives expression in all muscles. Comparison of the minimal promoter to Mhc genes of 10 Drosophila ... | ["5' Flanking Region", 'Animals', 'Animals, Genetically Modified', 'Base Composition', 'DNA Footprinting', 'Deoxyribonuclease I', 'Drosophila Proteins', 'Drosophila melanogaster', 'Embryo, Nonmammalian', 'Female', 'Gene Expression Regulation', 'Introns', 'Male', 'Muscles', 'Myosin Heavy Chains', 'Nuclear Proteins', 'Or... | 17,194,628 | [['G05.360.340.024.220.282', 'G05.360.340.024.340.137.295'], ['B01.050'], ['B01.050.050.136', 'B05.620.136'], ['G02.111.080'], ['E05.393.300'], ['D08.811.277.352.335.350.250'], ['D12.776.093.500.462'], ['B01.050.500.131.617.720.500.500.750.310.250.500'], ['A13.350', 'A16.331'], ['G05.308'], ['G05.360.340.024.220.400', ... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Agreement between hopelessness/helplessness and Montgomery-Asberg Depression Rating Scale in healthy individuals and in patients with benign breast disease and breast cancer: a prospective case-control study in Finland. | BACKGROUND: The relation between scoring for hopelessness/helplessness and the Montgomery-Asberg Depression Rating Scale (MADRS) in healthy study subjects (HSS) and in patients with benign breast disease (BBD) and breast cancer (BC) has not been compared in a prospective study. We, therefore, investigated hopelessness ... | ['Adult', 'Breast', 'Breast Neoplasms', 'Case-Control Studies', 'Depression', 'Female', 'Finland', 'Humans', 'Middle Aged', 'Prognosis', 'Surveys and Questionnaires'] | 25,862,881 | [['M01.060.116'], ['A01.236'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['F01.145.126.350'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.8... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A platform for glycoengineering a polyvalent pneumococcal bioconjugate vaccine using E. coli as a host. | Chemical synthesis of conjugate vaccines, consisting of a polysaccharide linked to a protein, can be technically challenging, and in vivo bacterial conjugations (bioconjugations) have emerged as manufacturing alternatives. Bioconjugation relies upon an oligosaccharyltransferase to attach polysaccharides to proteins, bu... | ['Animals', 'Bacterial Capsules', 'Escherichia coli', 'Genetic Engineering', 'Glycoproteins', 'Glycosylation', 'Humans', 'Pneumococcal Vaccines', 'Streptococcus pneumoniae', 'Vaccines, Conjugate', 'Vaccines, Synthetic'] | 30,792,408 | [['B01.050'], ['A20.186'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E05.393.420'], ['D09.400.430', 'D12.776.395'], ['G02.111.158.812', 'G02.607.299', 'G03.191.812'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D20.215.894.135.750.600'], ['B03.353.750.737.872.550', 'B03.510.400.800.872.550', 'B03... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Electrocutaneous spatial integration at threshold: the effects of electrode size. | Five experiments were carried out to investigate the effects of electrode size on threshold for current pulses that flowed between the ventral and dorsal sides of the right forearm. The main result was that the total current threshold decreases as the size of the cathode and anode increases at least up to 15 mm in diam... | ['Adult', 'Discrimination Learning', 'Electric Stimulation', 'Electrodes', 'Humans', 'Sensory Receptor Cells', 'Sensory Thresholds', 'Skin', 'Touch'] | 2,243,763 | [['M01.060.116'], ['F02.463.425.280'], ['E05.723.402'], ['E07.305.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.675.650.915', 'A08.800.950', 'A11.671.650.915'], ['F02.463.593.710'], ['A17.815'], ['F02.830.816.850', 'G11.561.790.850']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Hypercortisolemic depression is associated with the metabolic syndrome in late-life. | INTRODUCTION: Depression has been hypothesized to be associated with metabolic abnormalities which increase the risk of cardiovascular disease (CVD) and diabetes. Such a link could be due to increased HPA-axis activity. This study investigates the cross-sectional relationship between depression, urinary cortisol and me... | ['Affect', 'Aged', 'Blood Glucose', 'Cholesterol, HDL', 'Depression', 'Female', 'Humans', 'Hydrocortisone', 'Hypertension', 'Hypertriglyceridemia', 'Logistic Models', 'Male', 'Metabolic Syndrome', 'Obesity'] | 17,224,244 | [['F01.470.047'], ['M01.060.116.100'], ['D09.947.875.359.448.500'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'... | ['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Amantadine protects dopamine neurons by a dual action: reducing activation of microglia and inducing expression of GDNF in astroglia [corrected]. | Amantadine is commonly given to alleviate L-DOPA-induced dyskinesia of Parkinson's disease (PD) patients. Animal and human evidence showed that amantadine may also exert neuroprotection in several neurological disorders. Additionally, it is generally believed that this neuroprotection results from the ability of amanta... | ['Amantadine', 'Animals', 'Animals, Newborn', 'Astrocytes', 'Cells, Cultured', 'Coculture Techniques', 'Dopamine', 'Female', 'Glial Cell Line-Derived Neurotrophic Factor', 'Inflammation Mediators', 'Microglia', 'Neural Inhibition', 'Neurons', 'Neuroprotective Agents', 'Parkinsonian Disorders', 'Pregnancy', 'Rats', 'Rat... | 21,586,298 | [['D02.455.426.100.050.035'], ['B01.050'], ['B01.050.050.282'], ['A08.637.200', 'A11.650.200'], ['A11.251'], ['E05.481.500.374'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['D12.644.276.860.381.500', 'D12.776.467.860.381.500', 'D12.776.631.600.381.500', 'D23.529.850.381.500'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fundoplication enhances gastric emptying. | Fundoplication of the stomach is an established surgical treatment of gastroesophageal reflux. Its mechanism of action remains unclear. To assess its effect on gastric emptying, 21 patients (11 men, 10 women), median age 47 years (range 19-72), underwent a gastric emptying study before and 6 months after fundoplication... | ['Adult', 'Aged', 'Evaluation Studies as Topic', 'Female', 'Follow-Up Studies', 'Gastric Emptying', 'Gastroesophageal Reflux', 'Humans', 'Male', 'Middle Aged', 'Postoperative Period'] | 3,977,428 | [['M01.060.116'], ['M01.060.116.100'], ['E05.337', 'N05.715.360.335'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['G10.261.360.400'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E04.614.750', 'N02.421.585.753.750']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Thermal antinociceptive effect of orally administered gabapentin in healthy cats. | OBJECTIVE: To determine the thermal antinociceptive effect of various single doses of gabapentin administered orally in cats.ANIMALS: 6 healthy adult domestic shorthair cats.PROCEDURES: Baseline skin temperature and baseline thermal threshold were determined via application of a thermal probe to the thorax of each cat ... | ['Administration, Oral', 'Amines', 'Analgesics', 'Animals', 'Body Temperature', 'Cats', 'Cyclohexanecarboxylic Acids', 'Female', 'Gabapentin', 'Kinetics', 'Ovariectomy', 'Placebos', 'Skin Temperature', 'gamma-Aminobutyric Acid'] | 20,807,141 | [['E02.319.267.100'], ['D02.092'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['B01.050.150.900.649.313.750.377.750.250.125'], ['D02.241.223.268', 'D02.455.426.392.368.367.218'], ['D02.092.521', 'D02.241.081.114.500.350.300', 'D02.241.223.268.469', 'D02.455.426.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Histological studies of the mode of origin of tumors. | All of the tubular adenocarcinomas of early gastric cancer in humans showed gentle transitions from surrounding normal to neoplastic epithelium. In mammary carcinomas in C3H/He mice, known as viral tumors, there were also transitional appearances from normal to cancer cells. Furthermore, it was possible in rats to trac... | ['Animals', 'Cell Transformation, Neoplastic', 'Female', 'Humans', 'Male', 'Mammary Neoplasms, Experimental', 'Mice', 'Mice, Inbred C3H', 'Mutation', 'Neoplasms', 'Rats', 'Sarcoma, Experimental', 'Stomach Neoplasms'] | 7,314,086 | [['B01.050'], ['C04.697.098.500', 'C23.550.727.098.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.531.500', 'C04.619.590', 'E05.598.500.496.843'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.388', 'B01.050.150.900.649.313.992.635.505.500.400.388'], ['G05.365.590'], ['C04'],... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Gold nanoparticles as localization markers for direct and live imaging of particle absorption through a Caco-2 cell monolayer using dark-field microscopy. | Recently, efforts have been made to reduce the size of food particles containing functional ingredients, since reducing the size is expected to improve intestinal absorption. However, the absorption mechanisms have yet to be fully clarified. Therefore, a microscopy-based method for studying interactions between the p... | ['Caco-2 Cells', 'Cell Membrane', 'Gold', 'Humans', 'Metal Nanoparticles', 'Microscopy', 'Particle Size', 'Surface Properties', 'Tumor Cells, Cultured'] | 22,232,226 | [['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['A11.284.149'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.637.512.600.500'], ['E01.370.350.515', 'E05.595', 'H01.671.617.562'], ['G02.712'], ['G02.860'], ['A11.251.860']] | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
High-value utilization of egg shell to synthesize Silver and Gold-Silver core shell nanoparticles and their application for the degradation of hazardous dyes from aqueous phase-A green approach. | The common household material, egg shell of Anas platyrhynchos is utilized for the synthesis of Silver and Gold-Silver core shell nanoparticles using greener, environment friendly and economic way. The egg shell extracts were acting as a stabilizing and reducing agents. This method avoids the use of external reducing a... | ['Animals', 'Catalysis', 'Coloring Agents', 'Egg Shell', 'Gold', 'Green Chemistry Technology', 'Metal Nanoparticles', 'Nanotechnology', 'Photolysis', 'Silver', 'Water Pollutants, Chemical', 'Water Purification'] | 25,978,558 | [['B01.050'], ['G02.130'], ['D27.720.233'], ['A13.316'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['J01.897.360'], ['J01.637.512.600.500'], ['H01.603', 'J01.897.520.600'], ['G02.740.685'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.544.812'], ['D27.888.284.903.655'], ['N06.850.780.200.800.800.900... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Effects of meal replacement therapy on metabolic outcomes in Thai patients with type 2 diabetes: A randomized controlled trial. | BACKGROUND: A meal replacement (MR) with a low glycemic index (GI) is possibly beneficial for glycemic control. However, the effects of MR on diabetes mellitus have not been studied among Thai patients with type 2 diabetes (T2DM).AIM: To compare metabolic outcomes between T2DM patients receiving the new MR formula (ONC... | ['Beverages', 'Blood Glucose', 'Body Mass Index', 'Body Weight', 'Diabetes Mellitus, Type 2', 'Diet', 'Female', 'Glycated Hemoglobin A', 'Glycemic Index', 'Humans', 'Lipids', 'Male', 'Meals', 'Middle Aged', 'Thailand', 'Waist Circumference'] | 30,270,717 | [['G07.203.100', 'J02.200'], ['D09.947.875.359.448.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C18.452.394.750.149', 'C19.246.300'], ['G07.203.6... | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 |
Identification of shiga toxin and intimin coding genes in Escherichia coli isolates from pigeons (Columba livia) in relation to phylotypes and antibiotic resistance patterns. | Shiga toxin-producing Escherichia coli (STEC) strains are responsible for outbreaks of human intestinal diseases worldwide. Pigeons are distributed in public areas and are potential reservoirs for pathogenic bacteria. One hundred fifty-four fresh fecal samples were obtained from trapped pigeons in southeast of Iran and... | ['Adhesins, Bacterial', 'Animals', 'Bird Diseases', 'Columbidae', 'DNA, Bacterial', 'Drug Resistance, Bacterial', 'Escherichia coli Infections', 'Escherichia coli Proteins', 'Feces', 'Iran', 'Microbial Sensitivity Tests', 'Phylogeny', 'Polymerase Chain Reaction', 'Shiga Toxins', 'Shiga-Toxigenic Escherichia coli'] | 22,105,907 | [['D12.776.097.120.050', 'D12.776.543.100.050', 'D23.050.161.050'], ['B01.050'], ['C22.131'], ['B01.050.150.900.248.165.150'], ['D13.444.308.212'], ['G06.099.225', 'G06.225.347', 'G07.690.773.984.269.347'], ['C01.150.252.400.310.330'], ['D12.776.097.275'], ['A12.459'], ['Z01.252.245.500.350'], ['E01.370.225.875.595', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
[Orthodontic correction of malpositioned teeth before restorative treatment: efficiency improvement using Temporary Anchorage Devices (TADs)]. | INTRODUCTION: Orthodontic treatment is a fundamental tool when approaching in a multidisciplinary manner a prosthetic rehabilitation, thanks to the possibility to place in an ideal position the involved teeth and to improve or even correct any periodontal defects. Several orthodontic tricks and version have been develo... | ['Humans', 'Malocclusion', 'Maxilla', 'Molar', 'Orthodontic Anchorage Procedures', 'Orthodontic Appliances', 'Treatment Outcome'] | 27,938,652 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.793.494'], ['A02.835.232.781.324.502.645', 'A14.521.645'], ['A14.549.167.860.525'], ['E06.658.337'], ['E06.658.453'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Modification of genetic regulation of a heterologous chitosanase gene in Streptomyces lividans TK24 leads to chitosanase production in the absence of chitosan. | BACKGROUND: Chitosanases are enzymes hydrolysing chitosan, a â-1,4 linked D-glucosamine bio-polymer. Chitosan oligosaccharides have numerous emerging applications and chitosanases can be used for industrial enzymatic hydrolysis of chitosan. These extracellular enzymes, produced by many organisms including fungi and bac... | ['Base Sequence', 'Chitosan', 'Glycoside Hydrolases', 'Molecular Sequence Data', 'Promoter Regions, Genetic', 'Recombinant Proteins', 'Streptomyces lividans'] | 21,310,076 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D05.750.078.139.500', 'D09.698.211.500'], ['D08.811.277.450'], ['L01.453.245.667'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.340.137.750.680'], ['D12.776.828'], ['B03.300.390.400.810.768.500', 'B03.510.024.997.775.500', 'B03.510.41... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
ALK rearrangement in lung adenocarcinoma with concurrent cervix and breast metastases: A case report. | Distant metastases of pulmonary adenocarcinoma are regularly observed in the bones, brain, adrenal gland, and liver, but rarely in the breast or cervix. In this report, we describe a novel case of concurrent cervix and breast metastases from lung adenocarcinoma, with ALK rearrangements that were strongly consistent bet... | ['Adenocarcinoma of Lung', 'Adult', 'Anaplastic Lymphoma Kinase', 'Breast Neoplasms', 'Female', 'High-Throughput Nucleotide Sequencing', 'Humans', 'Immunohistochemistry', 'Lung Neoplasms', 'Neoplasm Metastasis', 'Uterine Cervical Neoplasms'] | 30,144,282 | [['C04.557.470.200.025.022', 'C04.588.894.797.520.055'], ['M01.060.116'], ['D08.811.913.696.620.682.725.400.002', 'D12.776.543.750.630.002'], ['C04.588.180', 'C17.800.090.500'], ['E05.393.760.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Adiposity-related protection of intestinal tumorigenesis: interaction with dietary calcium. | Although high-calcium diets have been reported to reduce the risk of colorectal cancer, our preliminary data with the adenomatous polyposis coli (Apc) Min mutation (Min/+;Apc(Min/+)) mouse shows a paradoxical increase in intestinal tumor loads (> 65%) with high calcium diets. Since we previously demonstrated that incre... | ['Adiposity', 'Animals', 'Calcium, Dietary', 'Colorectal Neoplasms', 'Cyclin D1', 'Dose-Response Relationship, Drug', 'Germ-Line Mutation', 'Intestinal Neoplasms', 'Intestines', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Mutant Strains', 'Mice, Obese', 'Random Allocation', 'Weight Gain', 'beta Catenin'] | 17,640,161 | [['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['B01.050'], ['D01.146.395'], ['C04.588.274.476.411.307', 'C06.301.371.411.307', 'C06.405.249.411.307', 'C06.405.469.158.356', 'C06.405.469.491.307', 'C06.405.469.860.180'], ['D12.644.360.262.150.100', 'D12.776.167.218.15... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
TGF-beta1 enhances the expression of alpha-smooth muscle actin in cultured human pulpal fibroblasts: immunochemical and ultrastructural analyses. | Transforming growth factor-beta 1 (TGF-beta1) has been related to induce the expression of alpha-smooth muscle actin (alpha-SMA) in fibroblasts during repair. Because pulpal fibroblasts seem to be somewhat different from other fibroblasts, the present study investigated in vitro whether TGF-beta1 enhances the expressio... | ['Actins', 'Blotting, Western', 'Cells, Cultured', 'Dental Pulp', 'Fibroblasts', 'Fluorescent Antibody Technique', 'Gingiva', 'Humans', 'Microscopy, Electron, Transmission', 'Myoblasts, Smooth Muscle', 'Osteonectin', 'Phenotype', 'Tenascin', 'Transforming Growth Factor beta1', 'Vimentin'] | 17,963,954 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251'], ['A14.549.167.900.260'], ['A11.329.228'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effectiveness of influenza and pneumococcal polysaccharide vaccines against influenza-related outcomes including pneumonia and acute exacerbation of cardiopulmonary diseases: Analysis by dominant viral subtype and vaccine matching. | BACKGROUND: Influenza and pneumonia are leading causes of morbidity and mortality among the elderly. Although vaccination is a main strategy to prevent these infectious diseases, concerns remain with respect to vaccine effectiveness.METHODS: During three influenza seasons (2014-2015, 2015-2016 and 2016-2017), we evalua... | ['Acute Disease', 'Aged', 'Aged, 80 and over', 'Cardiovascular Diseases', 'Cohort Studies', 'Female', 'Humans', 'Influenza A Virus, H1N1 Subtype', 'Influenza A Virus, H3N2 Subtype', 'Influenza Vaccines', 'Influenza, Human', 'Lung Diseases', 'Male', 'Pneumococcal Vaccines', 'Pneumonia, Pneumococcal', 'Prospective Studie... | 30,521,553 | [['C23.550.291.125'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.480.968.405.400.214'], ['B04.820.480.968.405.400.300'], ['D20.215.894.899.302'], ['C01.748.310', 'C01.925... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A focus on health promotion and prevention through the development of the national men's health policy. | ISSUES ADDRESSED: The Australian Government announced its intention to develop a national men's health policy in June 2008. A focus on prevention was identified as a foundation principle that would underpin the development of this policy. This brief report provides a descriptive account of the key discussion points rel... | ['Australia', 'Health Education', 'Health Policy', 'Health Promotion', 'Humans', 'Male', 'Risk Reduction Behavior'] | 19,642,956 | [['Z01.639.100', 'Z01.678.100.373'], ['I02.233.332', 'N02.421.726.407'], ['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['I02.233.332.445', 'N02.421.726.407.579'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.145.699']] | ['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Metastatic potential in T1 and T2 colorectal cancer. | BACKGROUND/AIMS: Survival of patients with colorectal cancer confined to the muscularis propria (stage I) is excellent after curative resection. However, some patients are likely to develop lymph node and distant metastasis that can ultimately cause death. The purpose of this study was to identify the possible predicto... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Biopsy, Needle', 'Carcinoembryonic Antigen', 'Colorectal Neoplasms', 'Female', 'Humans', 'Immunohistochemistry', 'Logistic Models', 'Lymph Nodes', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Neoplasm Invasiveness', 'Neoplasm Staging', 'P... | 16,334,758 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['E01.370.225.500.384.100.119', 'E01.370.225.998.054.119', 'E01.370.388.100.100', 'E04.074.119', 'E04.665.100', 'E05.200.500.384.100.119', 'E05.200.998.054.119', 'E05.242.384.100.119'], ['D12.776.395.550.200.210', ... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
An in vitro and in silico identification of antibiofilm small molecules from seawater metaclone SWMC166 against Vibrio cholerae O1. | This study aimed to determine the antibiofilm activity of seawater microbes against Vibrio cholerae (VCO1) through functional metagenomics approach. A metagenomic library was constructed from Palk Bay seawater and the library was screened to identify the biofilm inhibitory metaclone. Metaclone SWMC166 (harbouring ?30 k... | ['Biofilms', 'Computer Simulation', 'Extracellular Polymeric Substance Matrix', 'Gene Expression Regulation, Bacterial', 'Hydrophobic and Hydrophilic Interactions', 'Metagenome', 'Molecular Docking Simulation', 'Peptide Hydrolases', 'Quorum Sensing', 'Seawater', 'Small Molecule Libraries', 'Thermodynamics', 'Vibrio cho... | 29,574,083 | [['A20.593', 'G06.120'], ['L01.224.160'], ['A20.593.500', 'G06.120.500'], ['G05.308.300'], ['G02.409'], ['G05.360.340.550'], ['E05.599.595.249', 'L01.224.160.249'], ['D08.811.277.656'], ['G04.085.700', 'G06.550.700'], ['G16.500.275.725.500'], ['D27.720.470.765'], ['G01.906'], ['B03.440.450.900.859.225.151', 'B03.660.25... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Guiding the location of nanoparticles into vesicular structures: a morphological study. | The present paper investigates the selective incorporation of preformed nanoparticles (hydrophobic Au-NP (2 nm); hydrophilic Au-NP (12 nm); hydrophobic CdSe-NP (1.9 nm); retrovirus-particles (approximately 30 nm)) into the interface of lipid vesicles and polymersomes via TEM and DLS investigations. Lipid membranes were... | ['Butadienes', 'Cadmium Compounds', 'Gels', 'Gold', 'Hydrophobic and Hydrophilic Interactions', 'Lipid Bilayers', 'Membranes, Artificial', 'Nanoparticles', 'Particle Size', 'Phosphatidylcholines', 'Polyethylene Glycols', 'Quaternary Ammonium Compounds', 'Retroviridae', 'Selenium Compounds', 'Surface Properties', 'Water... | 18,060,174 | [['D02.455.326.271.665.146.240'], ['D01.142'], ['D20.280.320', 'D26.255.165.320'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['G02.409'], ['D10.570.510', 'J01.637.087.500.510'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['J01.637.512.600'], ['G02.712'], ['D10.570.755.375.760.400.800'], ['D02.0... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Life spans of Duchenne muscular dystrophy patients in the hospital care program in Japan. | Analysis of 176 autopsy cases of Duchenne muscular dystrophy (DMD) demonstrated that (1) hospitalized patients showed longer life spans than their non-hospitalized affected maternal uncles, (2) patients hospitalized recently lived longer than those hospitalized in the past, and (3) pulmonary infection has become a less... | ['Adolescent', 'Adult', 'Child', 'Humans', 'Japan', 'Male', 'Muscular Dystrophies'] | 3,694,224 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.474.463', 'Z01.639.595'], ['C05.651.534.500', 'C10.668.491.175.500', 'C16.320.577']] | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Chitosan-g-poly(N-isopropylacrylamide) copolymers as delivery carriers for intracameral pilocarpine administration. | This study reports, for the first time, the development of a chitosan-g-poly(N-isopropylacrylamide) (Chi-PN) biodegradable in situ gelling delivery system for ocular pilocarpine administration through intracameral injection. The number of thermo-responsive polymer segments grafted onto the chitosan via carbodiimide-med... | ['Acrylic Resins', 'Administration, Ophthalmic', 'Animals', 'Cell Line', 'Chitosan', 'Drug Carriers', 'Glaucoma', 'Humans', 'Muscarinic Agonists', 'Pilocarpine', 'Rabbits', 'Spectroscopy, Fourier Transform Infrared'] | 28,088,634 | [['D05.750.716.822.111', 'D25.720.716.822.111', 'J01.637.051.720.716.822.111'], ['E02.319.267.120.805'], ['B01.050'], ['A11.251.210'], ['D05.750.078.139.500', 'D09.698.211.500'], ['D26.255.260', 'E02.319.300.380'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.519.625.120.140.500', 'D27.50... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Computed tomography in craniopharyngiomas. | Computed tomographic examinations of 28 children and 12 adults with surgically proved craniopharyngiomas were retrospectively studied for characteristic findings that might be diagnostic of this tumor. It was found that 8 of 10 children and 2 of 4 adults examined pre-operatively had at least 2 of 3 findings: calcificat... | ['Adolescent', 'Adult', 'Brain Neoplasms', 'Cerebral Ventricle Neoplasms', 'Cerebral Ventriculography', 'Craniopharyngioma', 'Female', 'Humans', 'Retrospective Studies', 'Tomography, X-Ray Computed'] | 307,256 | [['M01.060.057'], ['M01.060.116'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C04.588.614.250.195.205', 'C10.228.140.211.280', 'C10.551.240.250.200'], ['E01.370.350.578.937.190', 'E01.370.350.700.560.190', 'E01.370.376.537.750.190', 'E05.629.937.190'], ['C04.557.465.625.200', 'C04.557.580.625.200'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Composite hemangioendothelioma with neuroendocrine marker expression: an aggressive variant. | Aberrant expression of neuroendocrine markers is extremely rare in endothelial neoplasms, with only a single report describing three cases. Although originally classified as conventional angiosarcoma, further assessment of these tumors revealed a strikingly composite morphology composed of retiform and epithelioid elem... | ['Adolescent', 'Adult', 'Biomarkers, Tumor', 'Child', 'Female', 'Hemangioendothelioma', 'Humans', 'Male', 'Middle Aged', 'Young Adult'] | 28,731,049 | [['M01.060.057'], ['M01.060.116'], ['D23.101.140'], ['M01.060.406'], ['C04.557.645.375.370'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['M01.060.116.815']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dental erosion of nonindustrial origin. A clinical survey and classification. | A survey was made from the clinical records of 72 patients diagnosed as suffering from dental erosion of nonindustrial origin. The information surveyed included dietary history, relevant medical history, clinical examination, and color photographs of the affected teeth. A new classification of erosion is proposed and t... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Dental Enamel', 'Dentin', 'Diet', 'Female', 'Gastroesophageal Reflux', 'Humans', 'Male', 'Middle Aged', 'Occupational Diseases', 'Patient Care Planning', 'Tooth Erosion'] | 292,776 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Treatment of adult Berkitt-like lymphoma]. | AIM: To compare programs of chemotherapy used in adult Berkitt-like lymphoma (ABLL); to assess efficacy and toxicity of the protocol AblL-M-04.MATERIAL AND METHODS: 31 ABLL patients (23 males, 8 females, mean age 27 years) participated in the study performed in Hematological Research Center in 1995-2004. ABLL stage I, ... | ['Adolescent', 'Adult', 'Antineoplastic Combined Chemotherapy Protocols', 'Asparaginase', 'Burkitt Lymphoma', 'Cyclophosphamide', 'Daunorubicin', 'Disease Progression', 'Dose-Response Relationship, Drug', 'Doxorubicin', 'Female', 'Follow-Up Studies', 'Humans', 'Male', 'Mercaptopurine', 'Methotrexate', 'Middle Aged', 'P... | 16,116,910 | [['M01.060.057'], ['M01.060.116'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D08.811.277.087.116'], ['C01.925.256.466.313.165', 'C01.925.928.313.165', 'C04.557.386.480.150.165', 'C15.604.515.569.480.150.165', 'C20.683.515.761.480.150.165'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Association between leisure time physical activity and markers of chronic inflammation related to coronary heart disease. | BACKGROUND: Some markers of chronic inflammation have been recognized as predictors of cardiovascular risk in apparently healthy subjects and in patients with coronary heart disease (CHD). High sensitivity C-reactive protein (CRP) appears to be the most useful marker in clinical settings. Several studies reported assoc... | ['Adult', 'Biomarkers', 'C-Reactive Protein', 'Chronic Disease', 'Coronary Artery Disease', 'Cross-Sectional Studies', 'Exercise', 'Fibrinogen', 'Humans', 'Inflammation', 'Life Style', 'Male', 'Middle Aged', 'Recreation', 'Risk Factors', 'Serum Amyloid A Protein'] | 15,380,453 | [['M01.060.116'], ['D23.101'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['C23.550.291.500'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['G11.427.410.698.277', 'I03.350'], ['D12.776.124.0... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Distribution of 7-methylguanine and of replication sites in the different kinetic classes of DNA from rats treated with dimethylnitrosamine. | The distribution of 7-methylguanine in the families of repetitive and unique sequences of rat liver chromatin DNA has been studied using the technique of DNA-DNA reassociation. Rats were injected with di[14C]methylnitrosamine and chromatin DNA was prepared 3 h later. The distribution of 7-methylguanine was found to be ... | ['Animals', 'Base Sequence', 'Chromatin', 'DNA', 'DNA Repair', 'DNA Replication', 'Dimethylnitrosamine', 'Guanine', 'Kinetics', 'Liver', 'Male', 'Methylation', 'Nitrosamines', 'Nucleic Acid Renaturation', 'Rats'] | 704,360 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D13.444.308'], ['G02.111.222', 'G05.219'], ['G02.111.225', 'G05.226'], ['D02.654.442.225'], ['D03.633.100.759.758.399.454'], ['G01.374.661', 'G02.111.490'], ['A03.620... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Characteristics of women with mixed mass formation after evacuation following uterine artery chemoembolization for cesarean scar pregnancy. | PURPOSE: To explore the efficacy of treatment for early cesarean scar pregnancy (CSP) and to evaluate the characteristics of women with subsequent mixed mass formation.METHODS: Women with CSP, who received UACE followed by evacuation, were retrospectively analyzed. Clinical/sonographic characteristics in patients with ... | ['Adult', 'Cesarean Section', 'China', 'Chorionic Gonadotropin, beta Subunit, Human', 'Cicatrix', 'Embolization, Therapeutic', 'Female', 'Gestational Sac', 'Humans', 'Menstruation', 'Pregnancy', 'Pregnancy, Ectopic', 'Retrospective Studies', 'Treatment Outcome', 'Ultrasonography', 'Uterine Artery', 'Uterine Artery Embo... | 29,450,694 | [['M01.060.116'], ['E04.520.252.500'], ['Z01.252.474.164'], ['D06.472.699.322.326.125', 'D06.472.699.649.367.125', 'D12.644.548.726.367.125', 'D12.776.780.400.125', 'D23.101.140.325', 'D23.101.175'], ['A10.165.450.300', 'C23.550.355.274', 'G16.762.891.249'], ['E02.520.360', 'E02.926.500'], ['A16.535'], ['B01.050.150.90... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Masticatory muscle and temporomandibular joint pain in Croatian war veterans with posttraumatic stress disorder. | The aim of this study was to investigate the prevalence and intensity of masticatory muscle and temporomandibular joint (TMJ) pain in Croatian war veterans with posttraumatic stress disorder (PTSD). The examined group consisted of 100 Croatian war veterans, in whom PTSD had previously been diagnosed. Patients were comp... | ['Adult', 'Croatia', 'Humans', 'Male', 'Masticatory Muscles', 'Middle Aged', 'Pain Measurement', 'Stress Disorders, Post-Traumatic', 'Temporomandibular Joint Dysfunction Syndrome', 'Veterans'] | 22,397,254 | [['M01.060.116'], ['Z01.542.248.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.567.600', 'A14.530'], ['M01.060.116.630'], ['E01.370.600.550.324'], ['F03.950.750.500'], ['C05.500.607.221.897.897', 'C05.550.905.905', 'C05.651.243.897.897', 'C05.651.550.905', 'C07.320.610.291.897.897', 'C07.678.949'], [... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Intramolecular iron(II)-catalyzed aminobromination of allyl N-tosyloxycarbamates. | Allyl N-tosyloxycarbamates are found to be catalytically transformed into â-brominated oxazolidinones with FeBr(2)/n-Bu(4)NBr in t-BuOH. | ['Amination', 'Carbamates', 'Catalysis', 'Halogenation', 'Iron', 'Molecular Structure'] | 22,349,660 | [['G02.111.053', 'G02.607.110', 'G03.068'], ['D02.241.081.251'], ['G02.130'], ['G02.111.323', 'G03.360'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['G02.111.570', 'G02.466']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of endothelin-1 on duodenal bicarbonate secretion and mucosal integrity in rats. | Effects of endothelin-1 on gastric acid secretion, duodenal HCO3- secretion, and duodenal mucosal integrity were investigated in anesthetized rats, in comparison with those of TY-10957, a stable analogue of prostacyclin. A rat stomach mounted on an ex-vivo chamber or a proximal duodenal loop was perfused with saline, a... | ['Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Anti-Ulcer Agents', 'Antihypertensive Agents', 'Bicarbonates', 'Duodenal Ulcer', 'Duodenum', 'Endothelin-1', 'Epirizole', 'Epoprostenol', 'Gastric Acid', 'Hydrogen-Ion Concentration', 'Intestinal Mucosa', 'Male', 'Peptides, Cyclic', 'Rats', 'Rats, Sprague-Dawley',... | 10,707,886 | [['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D27.505.954.483.203'], ['D27.505.954.411.162'], ['D01.200.275.150.100', 'D01.248.497.158.165.100'], ['C06.405.469.275.800.348', 'C06.405.748.586.349'], ['A03.556.124.684.124', 'A03.556.875.249'], ['D12.644.276.400.225', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Placental secretion of androgens in the rat. | In contrast to the human placenta, which does not secrete androgens, the rat placenta synthesizes significant amounts of these steroids. The purpose of this study was to determine why the rat placenta does not secrete androgens before day 12 of pregnancy, to ascertain whether the rat placenta secretes more androstenedi... | ['Aldehyde-Lyases', 'Androgens', 'Androstenedione', 'Animals', 'Corpus Luteum', 'Cytochrome P-450 Enzyme System', 'Female', 'Gestational Age', 'Placenta', 'Pregnancy', 'Rats', 'Steroid 17-alpha-Hydroxylase', 'Substrate Specificity', 'Testosterone'] | 3,490,962 | [['D08.811.520.224.062'], ['D27.505.696.399.472.161'], ['D04.210.500.054.079.329', 'D04.210.500.578.502.112', 'D06.472.040.502.112', 'D06.472.334.851.968.875'], ['B01.050'], ['A05.360.319.114.630.278', 'A06.300.312.497.278'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['G07.345.500.325.235.968',... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Infant feeding patterns over the first year of life: influence of family characteristics. | BACKGROUND/OBJECTIVES: Early eating patterns and behaviors can determine later eating habits and food preferences and they have been related to the development of childhood overweight and obesity. We aimed to identify patterns of feeding in the first year of life and to examine their associations with family characteri... | ['Adult', 'Age Factors', 'Breast Feeding', 'Cohort Studies', 'Educational Status', 'Family Characteristics', 'Feeding Behavior', 'Female', 'France', 'Humans', 'Infant Food', 'Infant Nutritional Physiological Phenomena', 'Infant, Newborn', 'Longitudinal Studies', 'Male', 'Maternal Behavior', 'Parity', 'Principal Compone... | 23,299,715 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['N01.824.196'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', 'N01.224.361', 'N0... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]... | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 1 |
Write a Scientific Paper (WASP) - What can I publish [1]? Types of studies. | As an experienced writer, one is often asked the question "what can I publish" by younger and inexperienced colleagues who must publish. This paper will briefly review the reasons why academics publish and will then outline what kind of papers one may be able to publish with relative ease, using personal experience and... | ['Gray Literature', 'Medical Writing', 'Periodicals as Topic', 'Review Literature as Topic'] | 30,545,725 | [['L01.178.682.550'], ['L01.559.423.906.654'], ['L01.178.682.829.678'], ['L01.178.682.759']] | ['Information Science [L]'] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Transcriptional analysis of L-methionine catabolism in Brevibacterium linens ATCC9175. | The expression of genes possibly involved in L-methionine and lactate catabolic pathways were performed in Brevibacterium linens (ATCC9175) in the presence or absence of added L-methionine. The expression of 27 genes of 39 selected genes differed significantly in L-methionine-enriched cultures. The expression of the ge... | ['3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)', 'Acetolactate Synthase', 'Brevibacterium', 'Carbon-Sulfur Lyases', 'Chromatography, High Pressure Liquid', 'Gas Chromatography-Mass Spectrometry', 'Gene Expression Regulation, Bacterial', 'Methionine', 'Models, Biological', 'Oligonucleotide Array Sequence Analysis',... | 17,225,104 | [['D08.811.682.657.350.760'], ['D08.811.913.200.324', 'D12.776.331.049'], ['B03.510.024.175', 'B03.510.460.400.400.049.550'], ['D08.811.520.300'], ['E05.196.181.400.300'], ['E05.196.181.349.500', 'E05.196.566.500'], ['G05.308.300'], ['D02.886.030.676', 'D12.125.142.557', 'D12.125.154.549', 'D12.125.166.676'], ['E05.599... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sulfo-click reaction via in situ generated thioacids and its application in kinetic target-guided synthesis. | Herein, we describe a practical, one-pot variant of the sulfo-click reaction, in which 9-fluorenylmethyl-protected thioesters are rapidly deprotected and reacted further with sulfonylazides to give N-acyl sulfonamides. | ['Azides', 'Click Chemistry', 'Esters', 'Kinetics', 'Molecular Structure', 'Sulfhydryl Compounds', 'Sulfonamides'] | 21,892,513 | [['D01.625.100', 'D02.159'], ['E05.197.124', 'J01.897.836.249.124'], ['D02.241.400'], ['G01.374.661', 'G02.111.490'], ['G02.111.570', 'G02.466'], ['D02.886.489'], ['D02.065.884', 'D02.886.590.700']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Persistence of Yersinia antigens in peripheral blood cells from patients with Yersinia enterocolitica O:3 infection with or without reactive arthritis. | OBJECTIVE: To assess the persistence of bacterial antigens in peripheral blood cells from patients with Yersinia enterocolitica O:3-triggered reactive arthritis (ReA).METHODS: Peripheral blood samples were obtained from 20 patients with Y. enterocolitica O:3 infection (11 with ReA and 9 without). These samples were stu... | ['Antibodies, Bacterial', 'Antigens, Bacterial', 'Arthritis, Reactive', 'Electrophoresis, Polyacrylamide Gel', 'Fluorescent Antibody Technique, Indirect', 'Heat-Shock Proteins', 'Humans', 'Immunoblotting', 'Lipopolysaccharides', 'Monocytes', 'Neutrophils', 'Synovial Fluid', 'Yersinia Infections', 'Yersinia enterocoliti... | 9,588,737 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D23.050.161'], ['C01.100.500', 'C05.116.900.853.625.800.637', 'C05.550.114.099.500', 'C05.550.114.865.800.637'], ['E05.196.401.402', 'E05.301.300.319'], ['E01.370.225.500.607.512.240.310', 'E01.370.225.750.551.512.240.310'... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Constitutive mRNA expression of DNA repair-related genes as a biomarker for clinical radio-resistance: A pilot study in prostate cancer patients receiving radiotherapy. | PURPOSE: Repair of radiation-induced DNA damage is believed to play a critical role in the development of adverse reactions in radiotherapy patients. Constitutive mRNA expression of repair genes was investigated in such patients to analyze whether expression patterns are predictive for therapy-related acute side effect... | ['Biomarkers, Tumor', 'DNA Repair', 'Humans', 'Male', 'Neoplasm Proteins', 'Pilot Projects', 'Prostatic Neoplasms', 'RNA, Messenger', 'Radiation Tolerance'] | 16,966,187 | [['D23.101.140'], ['G02.111.222', 'G05.219'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.624'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['C04.588.945.440.770', 'C12.294.260.750', 'C12.294.565.625', 'C12.758.409.750'], ['D13.444.735.544'], ['G04.712', 'G07.738']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Post-operative renal function following nephrectomy as part of en bloc resection of retroperitoneal sarcoma (RPS). | BACKGROUND AND OBJECTIVES: Although resection of RPS with en bloc nephrectomy confers the potential benefit of improved locoregional tumor control, little has been published about the long-term post-operative renal function of these patients.METHODS: Retrospective review of 54 patients undergoing nephrectomy for RPS wa... | ['Aged', 'Creatinine', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Glomerular Filtration Rate', 'Humans', 'Kidney Failure, Chronic', 'Kidney Function Tests', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Neoplasm Staging', 'Nephrectomy', 'Outcome Assessment, Health Care', 'Postoperative Period', 'Pro... | 26,179,132 | [['M01.060.116.100'], ['D03.383.129.308.207'], ['C23.550.291.656'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E01.370.390.400.300', 'G08.852.357'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['E01.370.39... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Objective Acoustic Quantification of Perceived Voice Tremor Severity. | Purpose This study compared auditory-perceptual measures of presence/absence and severity of vocal tremor to acoustic markers of vocal tremor. The validity (both concurrent and diagnostic) of various acoustic markers of vocal tremor was also assessed. Method Fifty-six midvowel sustained [a:] recordings were selected to... | ['Adult', 'Aged', 'Audiologists', 'Female', 'Humans', 'Linear Models', 'Male', 'Middle Aged', 'Observer Variation', 'ROC Curve', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Severity of Illness Index', 'Signal Processing, Computer-Assisted', 'Speech Acoustics', 'Speech Perception', 'Speech Production M... | 31,619,112 | [['M01.060.116'], ['M01.060.116.100'], ['M01.526.485.170', 'N02.360.170'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', 'N05.715.360.750.695.460', 'N06.850.520.830.500.500', 'N06.850.520.830.750.425'], ['M01.060.116.630'], ... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Papillon-Lef?vre syndrome. A clinical and therapeutical contribution. | A clinical study of a patient with the Papillon-Lef?vre syndrome is presented. She had identifiable zones where cutaneous involvement was lacking, probably corresponding to areas free from the effects of attrition or trauma. The patient was treated with oral aromatic retinoid Ro 10-9359. An obvious response with marked... | ['Administration, Oral', 'Child, Preschool', 'Etretinate', 'Female', 'Humans', 'Keratoderma, Palmoplantar', 'Papillon-Lefevre Disease'] | 6,220,930 | [['E02.319.267.100'], ['M01.060.406.448'], ['D02.455.326.271.665.202.495.250', 'D02.455.849.131.495.250', 'D23.767.261.700.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.320.850.475', 'C17.800.428.435', 'C17.800.827.475'], ['C16.320.850.475.600', 'C17.800.428.435.600', 'C17.800.827.475.600']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mineral metabolism and mortality in dialysis patients: a reassessment of the K/DOQI guideline. | BACKGROUND: Several studies found associations between higher plasma calcium and phosphorus and mortality in dialysis patients. However, different predefined categories and reference values were applied and the precise shape of these relationships remains unclear.METHODS: We evaluated 1,621 patients from NECOSAD, a pro... | ['Adult', 'Aged', 'Bone and Bones', 'Calcium', 'Cause of Death', 'Comorbidity', 'Female', 'Follow-Up Studies', 'Humans', 'Hypercalcemia', 'Hyperphosphatemia', 'Kidney Failure, Chronic', 'Male', 'Middle Aged', 'Netherlands', 'Parathyroid Hormone', 'Peritoneal Dialysis', 'Phosphorus', 'Practice Guidelines as Topic', 'Pro... | 18,305,386 | [['M01.060.116'], ['M01.060.116.100'], ['A02.835.232', 'A10.165.265'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['N05.715.350.225', 'N06.850.490.687'], ['E05.318.372.500.750.249', 'N05.715.360... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[The value and limits of intervertebral cages in lumbar arthrodesis]. | Cages are not disk prosthesis, they not preserve intervertebral mobility. In selected cases they are useful to improve immediate intervertebral stability when lumbar interbody fusion is performed, they also avoid the risk of bone graft crushing before fusion is obtained thanks to their rigidity. In most cases, addition... | ['Bone Transplantation', 'Equipment Design', 'Humans', 'Lumbar Vertebrae', 'Orthopedic Fixation Devices', 'Risk Factors', 'Spinal Diseases', 'Spinal Fusion', 'Treatment Outcome'] | 11,105,598 | [['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['E05.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['E07.858.442.660', 'E07.858.690.725'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The crystal structure of the lumenal domain of Erv41p, a protein involved in transport between the endoplasmic reticulum and Golgi apparatus. | Erv41p is a conserved integral membrane protein that is known to play a role in transport between the endoplasmic reticulum and Golgi apparatus, part of the early secretory pathway of eukaryotes. However, the exact function of the protein is not known, and it shares very low sequence identity with proteins of known str... | ['Amino Acid Sequence', 'Binding Sites', 'Crystallography, X-Ray', 'Endoplasmic Reticulum', 'Golgi Apparatus', 'Membrane Proteins', 'Models, Molecular', 'Molecular Sequence Data', 'Saccharomyces cerevisiae', 'Saccharomyces cerevisiae Proteins', 'Sequence Alignment'] | 23,524,136 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.120'], ['E05.196.309.742.225'], ['A11.284.430.214.190.875.248'], ['A11.284.430.214.190.875.336'], ['D12.776.543'], ['E05.599.595'], ['L01.453.245.667'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['D12.776.354.750'], ['E05.393.751']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effect of colchicine and bisacodyl on rat intestinal transit and nitric oxide synthase activity. | BACKGROUND: Bisacodyl and colchicine affect smooth-muscle contractility, intestinal water, and electrolyte transport. Nitric oxide (NO) stimulates intestinal electrolyte secretion and has an important role as a mediator of intestinal motility. We therefore studied, in rats, the effects of these agents on nitric oxide s... | ['Animals', 'Bisacodyl', 'Colchicine', 'Disease Models, Animal', 'Gastrointestinal Agents', 'Gastrointestinal Transit', 'Intestinal Mucosa', 'Ketotifen', 'Male', 'Nitric Oxide Synthase', 'Rats', 'Rats, Sprague-Dawley', 'Reference Values'] | 9,282,971 | [['B01.050'], ['D02.455.426.559.389.657.239.132'], ['D03.132.225'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D27.505.954.483'], ['E01.370.372.310', 'G10.261.360.525'], ['A03.556.124.369', 'A10.615.550.444'], ['D02.886.778.370', 'D03.383.621.370', 'D03.383.903.370'], ['D08.811.682.664.500.772'], ['B01.050.150.90... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Machado-Joseph disease with retinal degeneration and dementia. | OBJECTIVES: To clarify the phenotypic varieties in Machado-Joseph disease (MJD).MATERIALS AND METHODS: We studied a 64-year-old man with ataxia, retinal degeneration and dementia neurologically, ophthalmologically and genetically.RESULTS: The patient noted dysesthesia of his hands at age 57 and later had memory disturb... | ['Brain', 'Cerebral Angiography', 'Contrast Media', 'Dementia', 'Fluorescein', 'Humans', 'Machado-Joseph Disease', 'Male', 'Middle Aged', 'Retinal Degeneration', 'Tomography, Emission-Computed, Single-Photon', 'Trinucleotide Repeat Expansion'] | 11,903,098 | [['A08.186.211'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['D27.505.259.500', 'D27.720.259'], ['C10.228.140.380', 'F03.615.400'], ['D02.455.426.779.347.390', 'D03.633.300.953.275.390', 'D04.711.347.390'], ['B... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Neutrophil immunosurveillance for heart transplant rejection: a prospective study. | Immunologic surveillance for rejection detection in human heart transplantation offers many potential advantages. To date, investigative efforts have focused primarily on the acquired immune system, particularly the lymphocyte. Little attention has been given to aspects of innate immune function. We have previously rep... | ['Adult', 'Aged', 'Apoptosis', 'CD11b Antigen', 'Female', 'Graft Rejection', 'Heart Transplantation', 'Histocompatibility Testing', 'Humans', 'Male', 'Middle Aged', 'Neutrophils', 'Prospective Studies', 'Respiratory Burst'] | 20,620,524 | [['M01.060.116'], ['M01.060.116.100'], ['G04.146.954.035'], ['D12.776.395.550.200.074.750', 'D12.776.543.550.200.093.750', 'D12.776.543.750.705.408.100.150', 'D12.776.543.750.705.833.062', 'D23.050.301.350.074.049'], ['G12.875.545.328'], ['E04.100.376.475', 'E04.928.220.390', 'E04.936.450.475'], ['E01.370.225.812.385',... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
FOXP1 expression is a prognostic biomarker in follicular lymphoma treated with rituximab and chemotherapy. | Follicular lymphoma (FL) is a clinically and molecularly highly heterogeneous disease, yet prognostication relies predominantly on clinical tools. We recently demonstrated that integration of mutation status of 7 genes, including EZH2 and MEF2B, improves risk stratification. We mined gene expression data to uncover gen... | ['Antineoplastic Agents, Immunological', 'Antineoplastic Combined Chemotherapy Protocols', 'Cyclophosphamide', 'Doxorubicin', 'Enhancer of Zeste Homolog 2 Protein', 'Forkhead Transcription Factors', 'Gene Expression Regulation, Neoplastic', 'Humans', 'Lymphoma, Follicular', 'MEF2 Transcription Factors', 'Middle Aged', ... | 29,122,756 | [['D27.505.954.248.384'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D02.455.526.728.650.730.243', 'D02.705.672.500.243'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['D05.500.781.750.250', 'D08.811.913.555.500.800.200.500.500.500', 'D12.776.660.235.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Goal-dependent modulation of the long-latency stretch response at the shoulder, elbow, and wrist. | Many studies have demonstrated that muscle activity 50-100 ms after a mechanical perturbation (i.e., the long-latency stretch response) can be modulated in a manner that reflects voluntary motor control. These previous studies typically assessed modulation of the long-latency stretch response from individual muscles ra... | ['Adult', 'Biomechanical Phenomena', 'Elbow', 'Evoked Potentials, Motor', 'Female', 'Goals', 'Humans', 'Male', 'Movement', 'Muscle, Skeletal', 'Reaction Time', 'Reflex, Stretch', 'Shoulder', 'Wrist'] | 26,445,871 | [['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['A01.378.800.420'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['F01.658.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.568', 'G11.427.410'], ['A02.633.567', 'A10.690.552.500'], ['E05.796.817', 'F02.830.650', 'F04.669.817', 'G11.561.677'], ['E01.370... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Sequence and functional analyses of the rice gene homologous to the maize Vp1. | The homologous gene of the maize Vp1 gene was isolated from rice (Oryza sativa). Sequence analysis revealed that the rice Vp1 gene (Osvp1) encodes a protein of 728 amino acids and is interupted by 5 introns at positions identical to those of the maize gene. Osvp1 transcript was detected in developing embryo as early as... | ['Amino Acid Sequence', 'Base Sequence', 'Gene Expression Regulation', 'Genes, Plant', 'Genes, Reporter', 'Genomic Library', 'Molecular Sequence Data', 'Oryza', 'Plant Proteins', 'RNA, Messenger', 'Recombinant Proteins', 'Seeds', 'Sequence Analysis, DNA', 'Sequence Homology, Amino Acid', 'Trans-Activators', 'Zea mays'] | 8,193,305 | [['G02.111.570.060', 'L01.453.245.667.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.308'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.360.340.024.340.435'], ['G05.360.325.425', 'G05.360.340.425'], ['L01.453.245.667'], ['B01.650.940.800.575.912.250.822.616'], ['D12.776.765'], ['D... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Active internal re-warming using a centrifugal pump and heat exchanger following haemorrhagic shock, surgical trauma and hypothermia in a porcine model. | BACKGROUND: The centrifugal vortex blood pump (CVBP) using heparin-bonded circuitry allows re-warming of hypothermic trauma patients without anticoagulation. Study objectives were to confirm efficacy, and to characterise the physiology of CVBP re-warming in a porcine model.METHODS: Sixteen pigs were randomised to conve... | ['Animals', 'Body Temperature', 'Female', 'Hypothermia', 'Models, Animal', 'Random Allocation', 'Resuscitation', 'Rewarming', 'Shock, Hemorrhagic', 'Swine', 'Time Factors', 'Treatment Outcome', 'Wounds and Injuries'] | 17,585,913 | [['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['C23.888.119.565'], ['E05.598'], ['E05.318.370.700', 'E05.581.500.805', 'N05.715.360.325.675', 'N06.850.520.445.700'], ['E02.365.647'], ['E02.891'], ['C23.550.414.980', 'C23.550.835.650'], ['B01.050.150.900.649.313.500.880'], ['G01.910.857'], ['E01.789.800', 'N04.761.5... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A comparative study of the effects of brinzolamide and dorzolamide on retinal oxygen saturation and ocular microcirculation in patients with primary open-angle glaucoma. | AIMS: To assess the effects of brinzolamide and dorzolamide on ocular haemodynamics and retinal oxygen saturation in patients with primary open-angle glaucoma (OAG).METHODS: Fifteen patients with OAG were evaluated in a randomised, cross-over, double-blind study. They were treated with either brinzolamide or dorzolamid... | ['Aged', 'Antihypertensive Agents', 'Blood Pressure', 'Carbonic Anhydrase Inhibitors', 'Contrast Sensitivity', 'Cross-Over Studies', 'Double-Blind Method', 'Female', 'Glaucoma, Open-Angle', 'Humans', 'Intraocular Pressure', 'Laser-Doppler Flowmetry', 'Male', 'Microcirculation', 'Middle Aged', 'Oxygen', 'Pilot Projects'... | 18,369,067 | [['M01.060.116.100'], ['D27.505.954.411.162'], ['E01.370.600.875.249', 'G09.330.380.076'], ['D27.505.519.389.200'], ['E01.370.380.850.950.500', 'F02.463.593.778.435.110', 'F02.463.593.932.281', 'F02.463.593.932.901.500', 'G14.940.500'], ['E05.318.370.150', 'N05.715.360.325.150', 'N06.850.520.445.150'], ['E05.318.370.30... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Vascular renin-angiotensin system in two-kidney, one clip hypertensive rats. | The possible role of the renin-angiotensin system in the maintenance of hypertension in two-kidney, one clip hypertensive rats was studied. Plasma renin activity rose rapidly and markedly in association with the elevation of blood pressure and then decreased gradually, although blood pressure remained high. Renin activ... | ['Angiotensin II', 'Angiotensins', 'Animals', 'Aorta', 'Arteries', 'Enalapril', 'Hypertension, Renal', 'Male', 'Mesenteric Arteries', 'Muscle, Smooth, Vascular', 'Peptidyl-Dipeptidase A', 'Rats', 'Rats, Inbred Strains', 'Renin', 'Renin-Angiotensin System', 'Vasoconstriction'] | 3,013,774 | [['D06.472.699.094.078', 'D12.644.400.070.078', 'D12.644.456.073.041', 'D12.644.548.058.078', 'D12.776.631.650.070.078', 'D23.469.050.050.050'], ['D06.472.699.094', 'D12.644.400.070', 'D12.644.456.073', 'D12.644.548.058', 'D12.776.631.650.070', 'D23.469.050.050'], ['B01.050'], ['A07.015.114.056'], ['A07.015.114'], ['D1... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection. | Mycobacterium tuberculosis (Mtb), possesses at least three type VII secretion systems, ESX-1, -3 and -5 that are actively involved in pathogenesis and host-pathogen interaction. We recently showed that an attenuated Mtb vaccine candidate (Mtb Äppe25-pe19), which lacks the characteristic ESX-5-associated pe/ppe genes, b... | ['Animals', 'Antigens, Bacterial', 'Bacterial Proteins', 'CD4-Positive T-Lymphocytes', 'Cross Reactions', 'Disease Models, Animal', 'Female', 'Flow Cytometry', 'Mice', 'Mice, Inbred C57BL', 'Mycobacterium tuberculosis', 'Th1 Cells', 'Tuberculosis Vaccines', 'Tuberculosis, Pulmonary'] | 27,467,705 | [['B01.050'], ['D23.050.161'], ['D12.776.097'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['G12.122.281'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Psychiatric disorders and headache familial recurrence: a study on 200 children and their parents. | The main aim of the study was to examine the relationship between headache and familial recurrence of psychiatric disorders in parents and their children. Headache history and symptomatology have been collected in a clinical sample of 200 patients and their families, using a semi-structured interview (ICHD-II criteria)... | ['Chi-Square Distribution', 'Child', 'Family Health', 'Female', 'Headache', 'Humans', 'Male', 'Mental Disorders', 'Multivariate Analysis', 'Parent-Child Relations', 'Parents', 'Recurrence'] | 19,352,592 | [['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['M01.060.406'], ['N01.400.300'], ['C23.888.592.612.441'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F03'], ['E05.318.740.150.500', 'N05.715.360.750.125.500', 'N06.850.520.830.150.500'], ['F01.829.263.370.290'], ['F0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
An auditory illusion predicted from a weighted cross-correlation model of binaural interaction. | In humans, the lateral movement of an acoustic source produces dynamic changes in the relative sound-pressure level and time of arrival of the acoustic wave at the 2 ears. The dynamic nature of these cues is assumed to play an important role in the perception of lateral motion. A phenomenon of auditory motion is report... | ['Auditory Perception', 'Computer Simulation', 'Humans', 'Illusions', 'Loudness Perception', 'Psychoacoustics', 'Sound Localization'] | 8,650,296 | [['F02.463.593.071', 'G07.888.125'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.762.400', 'C23.888.592.604.764.400', 'F01.700.750.400', 'F02.463.593.446'], ['F02.463.593.071.576', 'G07.888.125.576'], ['E01.370.382.375.060.530', 'E01.370.685.628', 'F04.096.753.628'], ['F02.463.593.07... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Dopamine D2 receptors labeled with [3H]raclopride in rat and rabbit brains. Equilibrium binding, kinetics, distribution and selectivity. | The binding properties of the substituted benzamide raclopride to dopamine D2 receptors were studied with membrane preparations from rat and rabbit neostriatum. An analysis of the association kinetics suggested a single binding site but the data from the dissociation experiments were better described by a two-site mode... | ['Animals', 'Binding, Competitive', 'Corpus Striatum', 'Kinetics', 'Male', 'Rabbits', 'Raclopride', 'Rats', 'Rats, Inbred Strains', 'Receptors, Dopamine', 'Receptors, Dopamine D2', 'Salicylamides', 'Sodium', 'Species Specificity', 'Spiperone', 'Tritium'] | 2,527,300 | [['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['A08.186.211.200.885.287.249.487'], ['G01.374.661', 'G02.111.490'], ['B01.050.150.900.649.313.968.700'], ['D02.065.277.761', 'D02.241.223.100.100.761', 'D02.241.223.100.200.937', 'D02.455.426.559.389.127.085.761', 'D02.455.426.559.389.127.250.937'], ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Whole cell ELISA for detection of tumor antigen expression in tumor samples. | We have developed a whole cell enzyme-linked immunosorbent assay (ELISA) that detects the melanoma antigens gp100 and S-100 in tumor samples from patients with metastatic melanoma and the antigen CA 125 in tumor samples from patients with ovarian carcinoma. The assay is relatively simple to perform and interpret withou... | ['Antigens, Neoplasm', 'CA-125 Antigen', 'Cancer Vaccines', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Flow Cytometry', 'Humans', 'Immunohistochemistry', 'Immunologic Tests', 'Melanoma', 'Melanoma-Specific Antigens', 'Membrane Glycoproteins', 'Neoplasm Proteins', 'Ovarian Neoplasms', 'Tumor Cells, Cultured', 'gp10... | 11,684,122 | [['D23.050.285'], ['D12.776.395.560.631.050', 'D23.050.285.050.225', 'D23.050.550.325.225', 'D23.101.140.075.225'], ['D20.215.894.200'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.71... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Attenuation of Th1 response in decoy receptor 3 transgenic mice. | The soluble decoy receptor 3 (DcR3) is a member of the TNFR superfamily. Because DcR3 is up-regulated in tumor tissues and is detectable in the sera of cancer patients, it is regarded as an immunosuppressor to down-regulate immune responses. To understand the function of DcR3 in vivo, we generated transgenic mice overe... | ['Adjuvants, Immunologic', 'Animals', 'Apoptosis', 'Cells, Cultured', 'Cytokines', 'Fas Ligand Protein', 'Humans', 'Immunity, Cellular', 'Lymphocyte Activation', 'Membrane Glycoproteins', 'Membrane Proteins', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred MRL lpr', 'Mice, Transgenic', 'Receptors, Cell Surface', 'Receptor... | 16,210,617 | [['D27.505.696.477.067'], ['B01.050'], ['G04.146.954.035'], ['A11.251'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['D12.644.276.374.750.249', 'D12.776.395.550.312', 'D12.776.467.374.750.249', 'D12.776.543.550.312', 'D23.529.374.750.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.050.400'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Refractory hypoglycaemia in patient with gastric outlet obstruction. | A 68-year-old male with a longstanding history of severe gastric outlet obstruction secondary to peptic stricture was found unconscious at home with profound hypoglycaemia. He denied history of fasting, diabetes mellitus or use of hypoglycaemic agents. Systemic examination and metabolic profile were unremarkable. Hypog... | ['Aged', 'Angiography', 'Diazoxide', 'Endosonography', 'Gastric Bypass', 'Gastric Outlet Obstruction', 'Glucose', 'Humans', 'Hyperinsulinism', 'Hypoglycemia', 'Male', 'Nesidioblastosis', 'Pancreas', 'Pancreatic Diseases', 'Pyloric Stenosis'] | 25,564,641 | [['M01.060.116.100'], ['E01.370.350.700.060', 'E01.370.370.050'], ['D02.886.590.700.135.300', 'D02.886.655.500.300', 'D03.633.100.174.300'], ['E01.370.350.850.280'], ['E02.650.500.062.249', 'E04.035.398.385', 'E04.062.249', 'E04.210.457.430'], ['C06.405.748.340'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Immediate-early baculovirus genes transactivate the p143 gene promoter of Autographa californica nuclear polyhedrosis virus. | Trans-acting regulatory components of Autographa californica nuclear polyhedrosis virus (AcMNPV) were studied in a transient assay system for their ability to activate the p143 gene promoter. A region including 502 nt upstream of the AUG of the p143 gene was linked to the bacterial chloramphenicol acetyltransferase (CA... | ['Animals', 'Baculoviridae', 'Cell Line', 'DNA-Binding Proteins', 'Genes, Viral', 'Immediate-Early Proteins', 'Moths', 'Promoter Regions, Genetic', 'Restriction Mapping', 'Trans-Activators', 'Transcriptional Activation', 'Viral Proteins'] | 8,337,840 | [['B01.050'], ['B04.280.065', 'B04.525.100'], ['A11.251.210'], ['D12.776.260'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['D12.776.460', 'D12.776.964.925.968'], ['B01.050.500.131.617.720.500.500.937.650'], ['G02.111.570.080.689.675', 'G05.360.080.689.675', 'G05.360.340.024.... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vitro effects of estrogen and progesterone containing drugs on human erythrocyte carbonic anhydrase I and II isozymes in women smokers and nonsmokers. | BACKGROUND: Carbonic anhydrases (CAs), a group of metalloenzymes, are involved in numerous physiological and pathological processes such as acid-base balance, gluconeogenesis, lipogenesis, ureagenesis, electrolyte secretion in various tissues, bone resorption and calcification, and tumorigenicity. In the current study,... | ['Adolescent', 'Adult', 'Carbonic Anhydrase I', 'Carbonic Anhydrase II', 'Erythrocytes', 'Estrogens', 'Female', 'Humans', 'Progesterone', 'Smoking'] | 26,239,150 | [['M01.060.057'], ['M01.060.116'], ['D08.811.520.241.300.150.100'], ['D08.811.520.241.300.150.200'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D27.505.696.399.472.277'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.829', 'D06.472.334.734.623', 'D06.472.334.851.687.750'], ['F01.1... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Laparoscopic surgery for pediatric varicoceles: Randomized controlled trial. | BACKGROUND/PURPOSE: The purpose of this investigation was to evaluate the advantages and the shortcomings of laparoscopic varicocelectomy compared with open traditional treatment of varicoceles.METHODS: A total of 654 patients were operated on for left-sided varicoceles over 5 years from 1995 to 2000. To evaluate the c... | ['Adolescent', 'Child', 'Humans', 'Laparoscopy', 'Male', 'Treatment Outcome', 'Varicocele'] | 11,987,088 | [['M01.060.057'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.388.250.520', 'E04.502.250.520'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'], ['C12.294.936', 'C14.907.903']] | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comprehensive testing of 10 different ankle braces. Evaluation of passive and rapidly induced stability in subjects with chronic ankle instability. | OBJECTIVE: The aim of the present investigation was to test the stability of 10 different ankle braces under passive and rapidly induced loading conditions in a population suffering from chronic ankle instability in order to provide objective information to choose or recommend an appropriate model for specific needs. I... | ['Adult', 'Ankle Joint', 'Braces', 'Chronic Disease', 'Female', 'Humans', 'Joint Instability', 'Male', 'Materials Testing', 'Range of Motion, Articular', 'Rotation', 'Torque'] | 12,206,944 | [['M01.060.116'], ['A02.835.583.378.062'], ['E07.858.442.743.319'], ['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.521'], ['E05.570'], ['E01.370.600.700', 'G11.427.760'], ['G01.482.703'], ['G01.374.860.500']] | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Magnetic nanoparticles loaded with functional RNA nanoparticles. | RNA is now widely acknowledged not only as a multifunctional biopolymer but also as a dynamic material for constructing nanostructures with various biological functions. Programmable RNA nanoparticles (NPs) allow precise control over their formulation and activation of multiple functionalities, with the potential to se... | ['Cell Line, Tumor', 'Drug Delivery Systems', 'Ferric Compounds', 'Humans', 'Magnetics', 'Magnetite Nanoparticles', 'Microscopy, Atomic Force', 'Microscopy, Electron, Transmission', 'Polyethyleneimine', 'RNA', 'Transfection'] | 30,215,080 | [['A11.251.210.190', 'A11.251.860.180'], ['E02.319.300'], ['D01.490.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.671.493'], ['J01.637.512.600.500.144.500'], ['E01.370.350.515.666.400', 'E05.595.666.400'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['D02.455.326.271.665.550.600', 'D02.491.650', 'D0... | ['Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Unique characteristics of ubiquitin-bonded complex play a pathological role in dentatorubral-pallidoluysian atrophy. | Abnormal complex formation of dentatorubral-pallidoluysian atrophy (DRPLA) protein and pathological ubiquitination of abnormal complex are two pathological processes involved in DRPLA neurodegeneration. Pathological ubiquitination and solubility in SDS and reducing agent are two unique characteristics of the DRPLA prot... | ['Adult', 'Aged', 'Alzheimer Disease', 'Electrophoresis, Polyacrylamide Gel', 'Humans', 'Middle Aged', 'Myoclonic Epilepsies, Progressive', 'Nerve Tissue Proteins', 'Neurodegenerative Diseases', 'Solubility', 'Ubiquitins'] | 10,527,837 | [['M01.060.116'], ['M01.060.116.100'], ['C10.228.140.380.100', 'C10.574.945.249', 'F03.615.400.100'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C10.228.140.490.375.130.650', 'C10.228.140.490.493.063.650'], ['D12.776.631'], ['C10.574'], ['G02.805'], [... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Cytokine response to lipoprotein lipid loading in human monocyte-derived macrophages. | BACKGROUND: Macrophage foam cell formation is a prominent feature of human atherosclerotic plaques, usually considered to be correlated to uptake of and inflammatory response to oxidized low density lipoproteins (OxLDL). However, there are alternative pathways for formation of macrophage foam cells and the effect of su... | ['Cells, Cultured', 'Cholesterol', 'Cytokines', 'Foam Cells', 'Humans', 'Interleukin-1', 'Interleukin-6', 'Interleukin-8', 'Lipid Metabolism', 'Lipoproteins', 'Macrophages', 'Monocytes', 'Triglycerides', 'Tumor Necrosis Factor-alpha'] | 16,800,873 | [['A11.251'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D12.644.276.374', 'D12.776.467.374', 'D23.529.374'], ['A11.329.372.368', 'A11.627.482.368', 'A11.733.397.368', 'A15.382.670.522.368', 'A15.382.680.397.368'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular cloning, expression and characterization of a chitosanase from Microbacterium sp. | A gene encoding a chitosanase (mschito) was cloned from Microbacterium sp. OU01. The ORF consists of 801 bp which encoded a polypeptide of 266 amino acid residues. The deduced amino acid sequence shows 98% identity to that of the chitosanase reported in Pseudomonas sp. A-01. In addition, the fusion protein containing M... | ['Amino Acid Sequence', 'Biotechnology', 'Chitosan', 'Cloning, Molecular', 'DNA Primers', 'DNA, Complementary', 'Escherichia coli', 'Genome', 'Genome, Bacterial', 'Glycoside Hydrolases', 'Gram-Positive Bacteria', 'Molecular Sequence Data', 'Open Reading Frames', 'Recombinant Proteins', 'Spectrometry, Mass, Electrospray... | 17,563,859 | [['G02.111.570.060', 'L01.453.245.667.060'], ['H01.158.550', 'J01.897.120'], ['D05.750.078.139.500', 'D09.698.211.500'], ['E05.393.220'], ['D13.695.578.424.450.275', 'D27.720.470.530.600.223.600'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['B03.440.450.425.325.300', 'B03.660.250.15... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 |
Narcissistic vulnerability is a common cause for depression in patients with Gilles de la Tourette syndrome. | The aim of this study was to assess for the first time different dimensions of narcissistic self-regulation in a large cohort of adult patients with Gilles de la Tourette syndrome (GTS) (n=50). From preliminary studies it is suggested that narcissistic personality trait and disorder, respectively, are relatively uncomm... | ['Adult', 'Comorbidity', 'Depression', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mood Disorders', 'Narcissism', 'Personality Disorders', 'Personality Inventory', 'Quality of Life', 'Surveys and Questionnaires', 'Tourette Syndrome', 'Young Adult'] | 26,548,979 | [['M01.060.116'], ['N05.715.350.225', 'N06.850.490.687'], ['F01.145.126.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F03.600'], ['F02.739.794.582'], ['F03.675'], ['F04.711.647.513'], ['I01.800', 'K01.752.400.750', 'N06.850.505.400.425.837'], ['E05.318.308.980', 'N05.715.360.300.800', '... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.