Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Integrating sorghum whole genome sequence information with a compendium of sorghum QTL studies reveals uneven distribution of QTL and of gene-rich regions with significant implications for crop improvement. | A comprehensive analysis was conducted using 48 sorghum QTL studies published from 1995 to 2010 to make information from historical sorghum QTL experiments available in a form that could be more readily used by sorghum researchers and plant breeders. In total, 771 QTL relating to 161 unique traits from 44 studies were ... | ['Breeding', 'Chromosome Mapping', 'Crops, Agricultural', 'Genes, Plant', 'Genetic Linkage', 'Genetic Markers', 'Genome, Plant', 'Models, Genetic', 'Quantitative Trait Loci', 'Sorghum'] | 21,484,332 | [['E05.820.150', 'G05.090'], ['E05.393.183'], ['B01.650.160', 'G07.203.300.300', 'J02.500.300'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['G05.348'], ['D23.101.387', 'G05.695.450'], ['G05.360.340.365'], ['E05.599.395.397'], ['G05.360.340.024.380.937'], ['B01.650.940.800.575.912.250.822.894']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Processes of the survival of embryonic amygdala tissue after transplantation into different parts of the brain of adult rats]. | Histological examination of the Nissl and Golgi stained neurons revealed that the amygdalar embryonic grafts survive in the adult rat brain. Some quantitative characteristics, such as index of the parenchymal integration, growth potential, neuronal density and vascularization index were used for objective estimation of... | ['Amygdala', 'Animals', 'Brain', 'Cell Differentiation', 'Cell Fusion', 'Cerebral Cortex', 'Embryo, Mammalian', 'Graft Survival', 'Liver Transplantation', 'Male', 'Neuroglia', 'Neurons', 'Rats', 'Time Factors'] | 3,328,827 | [['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['B01.050'], ['A08.186.211'], ['G04.152'], ['E05.242.307', 'G04.155'], ['A08.186.211.200.885.287.500'], ['A16.254'], ['G12.875.545.340'], ['E02.095.147.725.490', 'E04.210.650', 'E04.936.450.490', 'E04.936.580.490'], ['A08.637', 'A11.650'], ['A08.675', 'A11.67... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pulmonary fungal granulomas and fibrinous pneumonia caused by different hypocrealean fungi in reptiles. | In contrast to fungal dermatitis, fungal glossitis and disseminated visceral mycosis, fungal infection of the lung has so far rarely been described in reptiles. Pulmonary fungal granulomas were diagnosed histopathologically within the scope of post mortem examinations. Fragments of the 18S-internal transcribed spacer1-... | ['Alligators and Crocodiles', 'Animals', 'Beauveria', 'Boidae', 'DNA, Ribosomal', 'Fibrin', 'Granuloma', 'Humans', 'Hypocreales', 'Lizards', 'Lung', 'Metarhizium', 'Mycoses', 'Phylogeny', 'Pneumonia', 'Reptiles', 'Zoonoses'] | 30,322,534 | [['B01.050.150.900.833.100'], ['B01.050'], ['B01.300.107.501.100', 'B01.300.381.103'], ['B01.050.150.900.833.672.125.500'], ['D13.444.308.475'], ['D12.776.124.270'], ['C15.604.515.292', 'C23.550.382'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.300.107.501'], ['B01.050.150.900.833.393'], ['A04.411'], ['B01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Water permeation barrier in isolated cutaneous newborn rat epidermis. | Abnormal water barrier function occurs in irritated skin and certain cutaneous diseases. Methods have been compared for separating the epidermis (site of the barrier) from the whole skin without disturbing the barrier function. The epidermis was separated from newborn rat skin by (1) exposure to 10% trypsin at 4 degree... | ['Animals', 'Animals, Newborn', 'Cell Culture Techniques', 'Diffusion', 'Endopeptidases', 'Epidermis', 'Hot Temperature', 'Rats', 'Trypsin', 'Water'] | 10,334,630 | [['B01.050'], ['B01.050.050.282'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G01.202', 'G02.196'], ['D08.811.277.656.300'], ['A10.272.497', 'A17.815.250'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Sperm competition mechanisms, confidence of paternity, and the evolution of paternal care in the golden egg bug (Phyllomorpha laciniata). | Theoretical models predict how paternal effort should vary depending on confidence of paternity and on the trade-offs between present and future reproduction. In this study we examine patterns of sperm precedence in Phyllomorpha laciniata and how confidence of paternity influences the willingness of males to carry eggs... | ['Animals', 'Biological Evolution', 'Heteroptera', 'Male', 'Paternal Behavior', 'Polymorphism, Restriction Fragment Length', 'Reproduction', 'Selection, Genetic', 'Sexual Behavior, Animal', 'Spain', 'Spermatozoa'] | 12,836,824 | [['B01.050'], ['G05.045', 'G16.075'], ['B01.050.500.131.617.412.420'], ['F01.829.263.370.330'], ['G05.365.795.595'], ['G08.686.784'], ['G05.783'], ['F01.145.113.252.748'], ['Z01.542.846'], ['A05.360.490.890', 'A11.497.760']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
The role of neuroscience within psychology: A call for inclusiveness over exclusiveness. | In the present article, we appraise the increasingly prominent role of neuroscience within psychology and offer cautions and recommendations regarding the future of psychology as a field. We contend that the conflict between eliminative reductionism (the belief that the neural level of analysis will eventually render t... | ['Humans', 'Neurosciences', 'Psychology', 'Research'] | 26,766,765 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.158.610'], ['F04.096.628'], ['H01.770.644']] | ['Organisms [B]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Lesions of the periaqueductal gray block the medial preoptic area-induced activation of the urethrogenital reflex in male rats. | The medial preoptic area (MPOA) is important for male sexual behavior, including erections and ejaculation. Stimulation of the MPOA evokes urethrogenital reflex-like responses. However, the descending pathways mediating this response are unknown. We examined the effect of bilateral lesions of the periaqueductal gray (P... | ['Animals', 'Blood Pressure', 'Brain Diseases', 'Electric Stimulation', 'Male', 'Penile Erection', 'Periaqueductal Gray', 'Preoptic Area', 'Rats', 'Rats, Sprague-Dawley', 'Reflex', 'Sexual Behavior, Animal', 'Time Factors'] | 15,337,249 | [['B01.050'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C10.228.140'], ['E05.723.402'], ['G08.686.784.717'], ['A08.186.211.132.659.413.875.595'], ['A08.186.211.180.497.342.450', 'A08.186.211.200.317.357.342.450'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['E01.37... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Synthetic Steroid Hormones Regulated Cell Proliferation Through MicroRNA-34a-5p in Human Ovarian Endometrioma. | Endometriosis is the hormone-dependent product of endometrial tissue found outside the uterus. Recently, micro-RNAs (miRNAs) were shown to play a role in endometriotic lesion development. However, the mechanism of steroid hormones responsible for miRNA remains obscure. In the present study, we assayed for the effects o... | ['Animals', 'Cell Proliferation', 'Cell Survival', 'Cells, Cultured', 'Danazol', 'Endometriosis', 'Estradiol', 'Female', 'Gene Expression Regulation', 'Humans', 'Medroxyprogesterone Acetate', 'Mice', 'MicroRNAs', 'Ovarian Diseases', 'Progesterone', 'Receptor, Notch1', 'Transcriptome', 'Up-Regulation'] | 26,819,477 | [['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['G04.346'], ['A11.251'], ['D04.210.500.745.432.235'], ['C13.351.500.163'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.829.395.700.500'], ['B01.050.150.900.649.313.9... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Simple microwave and thermal cycler boiling methods for preparation of cervicovaginal lavage cell samples prior to PCR for human papillomavirus detection. | Sample preparation is an important step in the detection of viral DNA by the polymerase chain reaction (PCR) technique. The method used should achieve release of cellular DNA with the minimum of manipulation steps so as to reduce the possibility of contamination. The present report demonstrates that either microwaving ... | ['Carcinoma in Situ', 'Cervix Uteri', 'DNA Probes, HPV', 'DNA, Viral', 'Epithelium', 'Female', 'Hot Temperature', 'Humans', 'Microwaves', 'Papillomaviridae', 'Polymerase Chain Reaction', 'Specimen Handling', 'Therapeutic Irrigation', 'Tumor Virus Infections', 'Uterine Cervical Neoplasms', 'Vagina'] | 8,227,280 | [['C04.557.470.200.240'], ['A05.360.319.679.256'], ['D13.444.600.223.555', 'D27.505.259.750.600.223.620', 'D27.720.470.530.600.223.620'], ['D13.444.308.568'], ['A10.272'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.050.1... | ['Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Treatment outcomes for older depressed patients with earlier versus late onset of first depressive episode: a Sequenced Treatment Alternatives to Relieve Depression (STAR*D) report. | OBJECTIVE: Controversy exists whether age at onset of the first depressive episode predicts chance of response and remission or the timing of such outcome. In this study of older depressed outpatients, the authors evaluated whether the age at onset of the first major depressive episode (MDE) was related to clinical out... | ['Age of Onset', 'Aged', 'Citalopram', 'Depressive Disorder, Major', 'Humans', 'Kaplan-Meier Estimate', 'Middle Aged', 'Regression Analysis', 'Serotonin Uptake Inhibitors', 'Treatment Outcome'] | 18,165,462 | [['N05.715.350.075.100', 'N06.850.490.250.100'], ['M01.060.116.100'], ['D02.092.831.170', 'D02.626.320', 'D03.633.100.127.187'], ['F03.600.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.998.650', 'N05.715.360.750.795.650', 'N06.850.520.830.998.650'], ['M01.060.116.630'], ['E05.318.740.750', '... | ['Health Care [N]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Ambient and biochemical effect monitoring of workers exposed to ethylene oxide. | OBJECTIVES: Ethylene oxide is an alkylating agent known to be a directly acting mutagen and carcinogen. This study describes the relationship between workplace ambient air concentrations of ethylene oxide and the concentration of N-2-hydroxyethylvaline in the globin of exposed workers.METHODS: During the sterilization ... | ['Air Pollution, Indoor', 'Environment, Controlled', 'Environmental Monitoring', 'Ethylene Oxide', 'Gas Chromatography-Mass Spectrometry', 'Humans', 'Male', 'Occupational Exposure', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Valine'] | 9,523,244 | [['N06.850.460.100.080'], ['N06.230.150'], ['N06.850.460.350.080', 'N06.850.780.375'], ['D02.355.291.411.417'], ['E05.196.181.349.500', 'E05.196.566.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.460.350.600'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.31... | ['Health Care [N]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The partitioning behavior of persistent toxicant organic contaminants in eutrophic sediments: Coefficients and effects of fluorescent organic matter and particle size. | In the shallow lakes, the partitioning of organic contaminants into the water phase from the solid phase might pose a potential hazard to both benthic and planktonic organisms, which would further damage aquatic ecosystems. This study determined the concentrations of polycyclic aromatic hydrocarbons (PAHs), organochlor... | ['Geologic Sediments', 'Hydrocarbons, Chlorinated', 'Lakes', 'Organic Chemicals', 'Particle Size', 'Polycyclic Aromatic Hydrocarbons', 'Solubility', 'Water Pollutants, Chemical'] | 27,427,173 | [['G01.311.330', 'G16.500.320'], ['D02.455.526.439'], ['G01.311.580', 'G16.500.275.280.500', 'N06.230.232.500'], ['D02'], ['G02.712'], ['D02.455.426.559.847', 'D04.615'], ['G02.805'], ['D27.888.284.903.655']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Relationships between polysomnographic variables, parameters of glucose metabolism, and serum androgens in obese adolescents with polycystic ovarian syndrome. | The aim of this study was to compare polysomnographic variables of obese adolescents with polycystic ovarian syndrome (PCOS) to those of healthy controls and to analyse whether polysomnographic variables correlate to parameters of body weight/body composition, to serum androgens and to parameters of glucose metabolism.... | ['Adolescent', 'Androgens', 'Androstenedione', 'Blood Glucose', 'Body Mass Index', 'Case-Control Studies', 'Dehydroepiandrosterone Sulfate', 'Female', 'Glucose', 'Humans', 'Obesity', 'Polycystic Ovary Syndrome', 'Polysomnography', 'Sleep', 'Sleep, REM', 'Testosterone', 'Wakefulness'] | 21,199,038 | [['M01.060.057'], ['D27.505.696.399.472.161'], ['D04.210.500.054.079.329', 'D04.210.500.578.502.112', 'D06.472.040.502.112', 'D06.472.334.851.968.875'], ['D09.947.875.359.448.500'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.500', 'N05.715.360.330.500... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
"Focus groups can be fun": the use of activity-oriented questions in focus group discussions. | Interest in focus group discussions has grown recently, and so has the recognition of them as a valuable method for qualitative data collection. Despite increasing popularity, they are not an easy option, and moderators must find appropriate ways to approach participants to achieve good-quality data. A path to reach th... | ['Focus Groups', 'Humans', 'Qualitative Research'] | 18,000,081 | [['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H01.770.644.241.850']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Improving Hepatitis C Screening in the Baby Boomer Birth Cohort in Rural South Dakota: A Medical Student HQIP Project. | Hepatitis C is a bloodborne viral infection that often leads to liver disease. Individuals born between 1945-1965 (baby boomer birth cohort) are five times more likely to have hepatitis C than other age groups due to blood transfusions and medical procedures performed before the discovery of the virus. The Centers for ... | ['Hepacivirus', 'Hepatitis C', 'Humans', 'Infant, Newborn', 'Infant, Newborn, Diseases', 'Mass Screening', 'South Dakota', 'Students, Medical'] | 32,135,047 | [['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750', 'C01.925.440.440', 'C01.925.782.350.350', 'C06.552.380.705.440'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['C16.614'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233.443', 'N05.715.360.300.800.438.500', 'N06.850.520.... | ['Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Simulated cystic renal lesions: quantitative X-ray phase-contrast CT--an in vitro phantom study. | PURPOSE: To determine if grating-based x-ray phase-contrast computed tomography (CT) can allow differentiation of simulated simple, protein-rich, hemorrhagic, and enhancing cystic renal lesions in an in vitro phantom.MATERIALS AND METHODS: An in vitro phantom specifically designed to simulate simple, protein-rich, hemo... | ['Humans', 'Kidney Diseases, Cystic', 'Phantoms, Imaging', 'Radiographic Image Interpretation, Computer-Assisted', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Tomography, X-Ray Computed', 'X-Ray Diffraction'] | 24,814,175 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.403', 'C13.351.968.419.403'], ['E07.671'], ['E01.158.600.680', 'E01.370.350.350.700', 'E01.370.350.700.705', 'L01.313.500.750.100.158.600.680'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.318.370.800', 'E05.318.... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
New middle Eocene omomyines (Primates, Haplorhini) from San Diego County, California. | The Friars Formation of San Diego County, California, has yielded a middle Eocene mammalian fauna from the early part of the Uintan North American Land Mammal Age. Prior research on the primate fauna from the Friars Formation provides evidence of one notharctine and multiple omomyine species, but many specimens collect... | ['Animals', 'California', 'Fossils', 'Haplorhini'] | 30,149,995 | [['B01.050'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['I01.076.368.584.311'], ['B01.050.150.900.649.313.988.400']] | ['Organisms [B]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Inhibitory effects of meta-iodo-benzylguanidine (MIBG) on endothelial histamine receptor binding. | Meta-iodo-benzylguanidine (MIBG), a selective inhibitor of mono-ADP-ribosylation, has been shown to inhibit histamine induced inositol-trisphosphate and prostacyclin production. The purpose of this study was to evaluate the effect of MIBG on the binding of histamine to the H1-receptor and to study its effects on phosph... | ['3-Iodobenzylguanidine', 'Binding, Competitive', 'Cells, Cultured', 'Choline', 'Cyclic GMP', 'Cytidine', 'Endothelium, Vascular', 'Histamine', 'Histamine H1 Antagonists', 'Humans', 'Inositol', 'Iodobenzenes', 'Nitric Oxide', 'Phospholipids', 'Propranolol', 'Pyrilamine', 'Receptors, Histamine H1', 'Serine', 'Umbilical ... | 9,468,342 | [['D02.078.370.510', 'D02.455.426.559.389.454.300', 'D02.455.526.581.496.300'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['A11.251'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Past tense formation and comprehension of passive sentences in Parkinson's disease: evidence from Greek. | The present study investigates the production of regular and irregular verbs in the past tense and the comprehension of passive sentences by Greek-speaking PD patients, and compares their behavior to that of normal speakers. Although the two groups manifest large scale differences at all the above constructions, the be... | ['Aged', 'Cognition', 'Cognition Disorders', 'Female', 'Greece', 'Humans', 'Language Disorders', 'Male', 'Middle Aged', 'Parkinson Disease', 'Semantics', 'Verbal Learning'] | 16,098,379 | [['M01.060.116.100'], ['F02.463.188'], ['F03.615.250'], ['Z01.542.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.150.500', 'C23.888.592.604.150.500'], ['M01.060.116.630'], ['C10.228.140.079.862.500', 'C10.228.662.600.400', 'C10.574.928.750'], ['L01.559.598.745'], ['F02.463.425.952']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Fetal gut-like differentiation in gallbladder cancer. | Adenocarcinomas showing fetal gut-like (enteroblastic) differentiation can arise in a variety of organs and are frequently accompanied by an elevated serum á-fetoprotein (AFP) level. However, no study has investigated fetal gut-like differentiation in gallbladder cancer in detail. Herein, we performed morphological and... | ['Adenocarcinoma', 'Aged', 'Aged, 80 and over', 'Cell Differentiation', 'DNA Mutational Analysis', 'Enterocytes', 'Female', 'Gallbladder Neoplasms', 'Glypicans', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Mutation', 'Neoplasm Staging', 'Neoplastic Stem Cells', 'Proto-Oncogene Proteins B-raf', 'Proto-Onco... | 28,970,139 | [['C04.557.470.200.025'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G04.152'], ['E05.393.760.700.300'], ['A03.556.124.369.290', 'A10.615.550.444.290', 'A11.436.290'], ['C04.588.274.120.401', 'C06.130.320.401', 'C06.130.564.401', 'C06.301.120.401'], ['D12.776.395.550.448.500', 'D12.776.395.650.350.249', 'D12.776.5... | ['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Simultanagnosia following perinatal hypoxia: a possible pediatric variant of Balint syndrome. | A 7-year-old boy with a history of low birth weight and perinatal hypoxia presented with symptoms of a spatial disorder of attention (simultanagnosia) and defective foot movements under visual control (optic ataxia), similar to a complex known as Balint's syndrome. Imaging revealed mature areas of ischemic damage in th... | ['Agnosia', 'Ataxia', 'Attention Deficit Disorder with Hyperactivity', 'Child', 'Diagnosis, Differential', 'Humans', 'Hypoxia, Brain', 'Magnetic Resonance Imaging', 'Male', 'Occipital Lobe', 'Parietal Lobe', 'Syndrome', 'Vision, Low', 'Visual Perception'] | 17,933,675 | [['C10.597.606.762.100', 'C23.888.592.604.764.100', 'F01.700.750.100'], ['C10.597.350.090', 'C23.888.592.350.090'], ['F03.625.094.150'], ['M01.060.406'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.624', 'C23.888.852.079.797'], ['E01.370.350.825.500'], ['A08.186.211.200.885.287.500.571']... | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Development of an internal amplification control system for a real-time PCR assay for detection of Neisseria meningitidis in CSF and EDTA blood. | The aim of this study was to assemble and assess a non-competitive internal amplification control (IAC) system targeting the Escherichia coli alanine racemase (alr) gene to include in a real-time polymerase chain reaction (PCR) assay for Neisseria meningitidis. Primers and hybridisation probes specific for the IAC were... | ['DNA, Bacterial', 'Humans', 'Meningitis, Meningococcal', 'Neisseria meningitidis', 'Real-Time Polymerase Chain Reaction', 'Reference Values', 'Sensitivity and Specificity'] | 24,798,157 | [['D13.444.308.212'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.223.500.750', 'C01.150.252.400.625.549.449', 'C01.207.180.500.750', 'C10.228.228.180.500.750', 'C10.228.614.280.505'], ['B03.440.400.425.550.550.641', 'B03.660.075.525.520.500'], ['E05.393.620.500.706'], ['E05.978.810'], ['E05.318.370.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Cirrhotic rat livers with extensive fibrosis can be safely transduced with clinical-grade adenoviral vectors. Evidence of cirrhosis reversion. | Adenoviral vectors efficiently target normal liver cells; however, a clear-cut description of the safety boundaries for using adenovectors in hepatic cirrhosis has not been settled. With this in mind, we used a first-generation, replication-deficient adenoviral vector carrying the E. coli lacZ gene (Ad5betaGal) to moni... | ['Adenoviridae', 'Animals', 'DNA, Complementary', 'Genetic Therapy', 'Genetic Vectors', 'Liver Cirrhosis, Experimental', 'Matrix Metalloproteinase 8', 'Rats', 'Rats, Wistar', 'Tissue Distribution', 'Transduction, Genetic', 'Treatment Outcome'] | 11,857,071 | [['B04.280.030'], ['B01.050'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.260'], ['E02.095.301', 'E05.393.420.301'], ['G05.360.337'], ['C06.552.630.467', 'C23.550.355.412.467', 'E05.598.500.468'], ['D08.811.277.656.300.480.205.358', 'D08.811.277.656.300.480.525.700.300', 'D08.811.277.656.67... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
High overexpression of the human alpha-galactosidase A gene driven by its promoter in transgenic mice: implications for the treatment of Fabry disease. | BACKGROUND: Human alpha-galactosidase A (alpha-Gal A) is the lysosomal enzyme that cleaves alpha-galactosyl residues from glycoconjugates and is the deficient enzyme in Fabry disease. To date, there have been no studies on the regulation of this "housekeeping" gene.METHODS: Transgenic mice were established with either ... | ['Animals', 'DNA', 'Disease Models, Animal', 'Fabry Disease', 'Gene Dosage', 'Gene Expression Regulation, Enzymologic', 'Genetic Therapy', 'Humans', 'Mice', 'Mice, Knockout', 'Mice, Transgenic', 'Polymerase Chain Reaction', 'Promoter Regions, Genetic', 'alpha-Galactosidase'] | 12,033,283 | [['B01.050'], ['D13.444.308'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C10.228.140.163.100.435.825.200', 'C10.228.140.300.275.374', 'C14.907.253.329.374', 'C16.320.322.124', 'C16.320.565.189.435.825.200', 'C16.320.565.398.641.803.300', 'C16.320.565.595.554.825.200', 'C18.452.132.100.435.825.200', 'C18.452.584.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anthrax toxin triggers the activation of src-like kinases to mediate its own uptake. | AB-type toxins, like other bacterial toxins, are notably opportunistic molecules. They rely on target cell receptors to reach the appropriate location within the target cell where translocation of their enzymatic subunits occurs. The anthrax toxin, however, times its own uptake, suggesting that toxin binding triggers s... | ['Animals', 'Antigens, Bacterial', 'Bacterial Toxins', 'Cell Line', 'Cricetinae', 'Endocytosis', 'Enzyme Activation', 'Humans', 'MAP Kinase Kinase 1', 'Mice', 'Phosphotyrosine', 'Protein Binding', 'Proto-Oncogene Proteins c-fyn', 'RNA, Small Interfering', 'Receptors, Peptide', 'Substrate Specificity', 'Ubiquitination',... | 20,080,640 | [['B01.050'], ['D23.050.161'], ['D23.946.123'], ['A11.251.210'], ['B01.050.150.900.649.313.992.635.075.250'], ['G04.417'], ['G02.111.263', 'G03.328'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.700.565.100', 'D08.811.913.696.620.682.725.200.100', 'D12.644.360.440.100', 'D12.776.476.440.1... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inhibition of phorbol ester-induced monocytic differentiation and c-fms gene expression by dexamethasone: potential involvement of arachidonic acid metabolites. | The treatment of human U-937 leukemia cells with 12-O-tetradecanoylphorbol-13-acetate (TPA) is associated with induction of monocytic differentiation. However, the signaling pathways responsible for induction of the differentiated monocytic phenotype remain unclear. The present studies demonstrate that dexamethasone bl... | ['Arachidonic Acids', 'Cell Transformation, Neoplastic', 'Dexamethasone', 'Gene Expression Regulation, Leukemic', 'Humans', 'Leukemia', 'Monocytes', 'Phenotype', 'Proto-Oncogene Proteins', 'Receptor, Macrophage Colony-Stimulating Factor', 'Tetradecanoylphorbol Acetate', 'Tumor Cells, Cultured'] | 2,144,778 | [['D10.251.355.255.100', 'D10.251.355.310.166'], ['C04.697.098.500', 'C23.550.727.098.500'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['G05.308.370.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.337'], ['A11.118.637.555.652', 'A11.148.580', 'A11.627.624', 'A11.733.547', 'A15.145.229.63... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
HgCl2-induced perturbation of the T cell network in experimental allergic encephalomyelitis. I. In vitro characterization of T cells involved. | Mercuric chloride (HgCl2) induces in Lewis (LEW) rats a non-antigen-specific immunosuppression and is able to down-modulate experimental allergic encephalomyelitis in about 70% of the rats. The aim of the present study was to determine the frequencies of lymph node cells involved in the proliferative response to myelin... | ['Animals', 'CD4-Positive T-Lymphocytes', 'Cell Separation', 'Encephalomyelitis, Autoimmune, Experimental', 'Lectins', 'Lymph Nodes', 'Lymphocyte Activation', 'Mercuric Chloride', 'Myelin Basic Protein', 'Plant Lectins', 'Rats', 'Rats, Inbred Lew', 'T-Lymphocyte Subsets', 'T-Lymphocytes', 'T-Lymphocytes, Helper-Inducer... | 1,716,519 | [['B01.050'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['C10.114.703.300', 'C10.228.140.695.562.250', 'C10.314.350.250', 'C20.111.258.625.300', 'E05.598.500.500.500'], ['D12.776.503'], ['A10.549.400', 'A... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[The value of the cytocins and the solubility of theirs receptors in the serum of the patients with the cervical cancer]. | The study encompassed 146 women with recognized invasive cervical cancer in 4 clinical stages. Patients underwent therapy in Oncologic Gynaecology Department of Wroc?aw Medical University in 2001 and 2002 years. The correlation between pretreatment serum level of proangiogenic and inflammation factors--VEGF, sTNF-R1, I... | ['Adult', 'Aged', 'Aged, 80 and over', 'Biomarkers, Tumor', 'Case-Control Studies', 'Disease Progression', 'Female', 'Humans', 'Interleukin-6', 'Kaplan-Meier Estimate', 'Middle Aged', 'Neoplasm Staging', 'Poland', 'Prognosis', 'Receptors, Tumor Necrosis Factor, Type I', 'Retrospective Studies', 'Treatment Outcome', 'Ut... | 18,159,822 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D23.101.140'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.291.656'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.224', 'D12.776.467.374.465.202', 'D23.529.374.465.224'], ['E05.318.7... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Chemiluminescence in hypoxic brain--the first report. Correlation between energy metabolism and free radical reaction. | The possibility that cerebral ischemia or cerebral hypoxia may initiate a series of free radical reactions in brain tissue lipid constituents was explored by measuring sequential changes in chemiluminescence values and energy metabolism during brain hypoxia in the rat. Brain hypoxia was induced by means of arterial hyp... | ['Adenosine Diphosphate', 'Animals', 'Brain', 'Energy Metabolism', 'Free Radicals', 'Glucose', 'Glycolysis', 'Hypoxia, Brain', 'Lactates', 'Luminescent Measurements', 'Male', 'Oxidative Phosphorylation', 'Pyruvates', 'Rats', 'Rats, Inbred Strains'] | 6,506,118 | [['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['B01.050'], ['A08.186.211'], ['G03.295'], ['D01.339', 'D02.389'], ['D09.947.875.359.448'], ['G02.111.158.750', 'G03.191.750', 'G03.295.436', 'G03.493.360'], ['C10.228.140.624', 'C23.888.852.079.797'], ['D02.241.511.459'], ['E05.196.712.516... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
null | AUTOIMMUNITY AND MANAGEMENT OF THE IMMUNE-RELATED ADVERSE EFFECTS OF THE IMMUNE CHECKPOINT INHIBITORS: The immune checkpoint molecules such as CTLA-4 and PD-1 are involved in the tolerance mechanisms preventing the immune system to react against the self-antigens. When these receptors expressed on the lymphocyte membra... | ['Antibodies, Monoclonal', 'Autoimmune Diseases', 'Autoimmunity', 'CD4-Positive T-Lymphocytes', 'CTLA-4 Antigen', 'Humans', 'Immune Tolerance', 'Immunotherapy', 'Lymphocyte Activation', 'Lymphocytes, Tumor-Infiltrating', 'Neoplasms', 'Programmed Cell Death 1 Receptor', 'Tumor Microenvironment'] | 28,057,182 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['C20.111'], ['G12.450.192'], ['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['D12.776.465.782', 'D12.776.543.750.705.222.750', 'D23.050.301.264.894.158', 'D23.101.100.894.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Free energy barrier estimation of unfolding the alpha-helical surfactant-associated polypeptide C. | Molecular dynamics simulations were conducted to estimate the free energy barrier of unfolding surfactant-associated polypeptide C (SP-C) from an alpha-helical conformation. Experimental studies indicate that while the helical fold of SP-C is thermodynamically stable in phospholipid micelles, it is metastable in a mixe... | ['Amino Acid Sequence', 'Animals', 'Computer Simulation', 'Humans', 'Models, Molecular', 'Peptides', 'Protein Folding', 'Protein Structure, Secondary', 'Proteolipids', 'Pulmonary Surfactants', 'Solvents', 'Thermodynamics'] | 11,340,656 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['L01.224.160'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595'], ['D12.644'], ['G01.154.651', 'G02.111.688'], ['G02.111.570.820.709.600'], ['D10.570.780', 'D12.776.816'], ['D27.505.954.796.600'], ['D27.720.844'], ['G01.906']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Seizures induced by theophylline and isoniazid in mice. | Isoniazid-induced seizures respond poorly to anticonvulsants but well to pyridoxine (Vitamin B6); theophylline produces difficult-to-treat seizures with substantial morbidity and mortality. Theophylline therapy depresses plasma pyridoxal-5'-phosphate (PLP), the active metabolite of pyridoxine, suggesting that theophyll... | ['Animals', 'Antitubercular Agents', 'Bronchodilator Agents', 'Dose-Response Relationship, Drug', 'Female', 'Isoniazid', 'Mice', 'Pyridoxal Phosphate', 'Pyridoxine', 'Seizures', 'Theophylline'] | 10,349,711 | [['B01.050'], ['D27.505.954.122.085.255'], ['D27.505.696.663.050.110', 'D27.505.954.796.050.100'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.442.436', 'D03.066.349.410', 'D03.383.725.394.582'], ['B01.050.150.900.649.313.992.635.505.500'], ['D03.383.725.676.925.500.500', 'D08.211.740'], ['D03.383.725.676.925.875'], ... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Space cannot be cut-why self-identity naturally includes neighbourhood. | Psychology is not alone in its struggle with conceptualizing the dynamic relationship between space and individual or collective identity. This general epistemological issue haunts biology where it has a specific focus in evolutionary arguments. It arises because of the incompatibility between definitive logical system... | ['Environment', 'Humans', 'Selection, Genetic', 'Self Concept', 'Social Behavior', 'Social Environment'] | 21,302,152 | [['G16.500.275', 'N06.230'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.783'], ['F01.752.747.792'], ['F01.145.813'], ['I01.880.853.500']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Short- and mid-term results for aortic valve replacement in octogenarians. | Population over 80 years who require surgery for degenerative aortic stenosis has largely increased in the past decades. We have compared short- and mid-term results for conventional aortic valve replacement (AVR) for calcific-degenerative aortic stenosis in older and younger than 80 years operated at our institution b... | ['Age Factors', 'Aged', 'Aged, 80 and over', 'Aortic Valve Stenosis', 'Cardiovascular Diseases', 'Cerebrovascular Disorders', 'Chi-Square Distribution', 'Female', 'Heart Valve Prosthesis Implantation', 'Hospital Mortality', 'Humans', 'Kaplan-Meier Estimate', 'Logistic Models', 'Male', 'Odds Ratio', 'Patient Selection',... | 20,100,705 | [['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C14.280.484.048.750', 'C14.280.955.249'], ['C14'], ['C10.228.140.300', 'C14.907.253'], ['E05.318.740.994.300', 'G17.820.300', 'N05.715.360.750.750.200', 'N06.850.520.830.994.300'], ['E04.100.376.485', 'E04.650.410', 'E04.928.220.41... | ['Health Care [N]', 'Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Exposure and preventive behaviours toward ticks and Lyme disease in Canada: Results from a first national survey. | Lyme disease (LD) risk is increasing in Canada. In 2014, the government of Canada launched a national communication campaign to raise awareness and promote the adoption of individual preventive behaviours toward ticks and LD. The objectives of this study were to evaluate and compare the adoption of LD preventive behavi... | ['Adolescent', 'Adult', 'Aged', 'Animals', 'Canada', 'Data Collection', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Lyme Disease', 'Male', 'Middle Aged', 'Socioeconomic Factors', 'Surveys and Questionnaires', 'Tick Bites', 'Tick Control', 'Ticks', 'Young Adult'] | 27,771,334 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050'], ['Z01.107.567.176'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.400.536', 'C01.150.252.400.794.352.250', 'C01.920.930.513... | ['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 |
Precise spatial and temporal control of oxygen within in vitro brain slices via microfluidic gas channels. | The acute brain slice preparation is an excellent model for studying the details of how neurons and neuronal tissue respond to a variety of different physiological conditions. But open slice chambers ideal for electrophysiological and imaging access have not allowed the precise spatiotemporal control of oxygen in a way... | ['Animals', 'Brain', 'Calcium', 'Diffusion', 'Electrophysiology', 'Hippocampus', 'In Vitro Techniques', 'Mice', 'Microfluidic Analytical Techniques', 'Microfluidics', 'Neurons', 'Oxygen', 'Perfusion', 'Stroke', 'Time Factors'] | 22,905,255 | [['B01.050'], ['A08.186.211'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G01.202', 'G02.196'], ['H01.158.344.528', 'H01.158.782.236'], ['A08.186.211.180.405', 'A08.186.211.200.885.287.500.345'], ['E05.481'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.588.465'], ['E05.830.666', 'H01.671.808.500', ... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Synthesis and anabolic/androgenic evaluation of novel 9alpha-fluorosteroids. | 3Beta,11beta-dihydroxy-9alpha-fluor-5alpha-androstane-17-one (2), 3beta-acetoxy-9alpha-fluor-11beta-hydroxy-5alpha-androstane-17-one (3), 3beta-acetoxy-9alpha-fluor-11beta,17beta-dihydroxy-5alpha-androstane (4), 3beta,17beta-diacetoxy-9alpha-fluor-11beta-hydroxy-5alpha-androstane (5), 3beta-acetoxy-9alpha-fluor-11beta-... | ['Anabolic Agents', 'Androgens', 'Androstanes', 'Animals', 'Fluorine', 'Male', 'Muscles', 'Organ Size', 'Prostate', 'Rats', 'Rats, Wistar', 'Seminal Vesicles'] | 19,615,789 | [['D27.505.696.399.472.080'], ['D27.505.696.399.472.161'], ['D04.210.500.054'], ['B01.050'], ['D01.268.380.300'], ['A02.633', 'A10.690'], ['E01.370.600.115.100.660', 'E05.041.124.715', 'G07.100.100.660', 'G07.345.249.690'], ['A05.360.444.575', 'A10.336.707'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.9... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effects of hand acupuncture therapy on sleep quality in sleep disrupted adults: verification by polysomnography and cerebral blood flow test]. | PURPOSE: The purpose of this study was to identify the effects of hand acupuncture therapy on sleep quality by means of a sleep questionnaire, polysomnography and a cerebral blood flow test in 30-59 year old adults.METHODS: The study was a sham controlled design. Twenty-two adults were assigned to the pellet stimulatin... | ['Acupuncture Therapy', 'Adult', 'Cerebrovascular Circulation', 'Demography', 'Female', 'Hand', 'Humans', 'Male', 'Middle Aged', 'Polysomnography', 'Research Design', 'Sleep Stages', 'Sleep Wake Disorders', 'Ultrasonography, Doppler, Transcranial'] | 18,182,872 | [['E02.190.044'], ['M01.060.116'], ['G09.330.100.159'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.520.625'], ['E05.581.500', 'H01.770.644.728'], ['F02.830.855.796', 'G11.561.803.754'], ['C10.886', 'C23.888.592.796', 'F... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Diseases [C]... | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Radiofrequency ablation of idiopathic left ventricular tachycardia at the site of earliest activation as determined by noncontact mapping. | INTRODUCTION: The most effective method for guiding radiofrequency (RF) ablation of idiopathic left ventricular tachycardia (ILVT) has yet to be determined. We investigated the use of noncontact mapping in five patients with this condition.METHODS AND RESULTS: The multielectrode array was positioned in the left ventric... | ['Adult', 'Body Surface Potential Mapping', 'Catheter Ablation', 'Diastole', 'Electrocardiography', 'Female', 'Humans', 'Male', 'Middle Aged', 'Tachycardia, Ventricular'] | 11,059,972 | [['M01.060.116'], ['E01.370.370.380.240.850.100', 'E01.370.405.240.850.100'], ['E02.808.750.500', 'E04.014.760.500'], ['G09.330.580.295', 'G11.427.494.554.250', 'G11.427.494.570.295'], ['E01.370.370.380.240', 'E01.370.405.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.067.845.940... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
An association between the MICA-A5.1 allele and an increased susceptibility to oral squamous cell carcinoma in Japanese patients. | BACKGROUND: Recently, a new polymorphic gene family called the major histocompatibility complex class I chain-related gene A (MICA) was discovered about 40 kb centromeric to HLA-B gene. The MICA protein, expressed on epithelial cells and many kinds of tumor cells, serves to regulate immune function. The MICA protein is... | ['Adult', 'Aged', 'Aged, 80 and over', 'Alleles', 'Asian Continental Ancestry Group', 'CD8-Positive T-Lymphocytes', 'Carcinoma, Squamous Cell', 'Epidemiologic Methods', 'Female', 'Genetic Predisposition to Disease', 'HLA-B Antigens', 'Histocompatibility Antigens Class I', 'Humans', 'Male', 'Middle Aged', 'Mouth Neoplas... | 17,559,497 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G05.360.340.024.340.030'], ['M01.686.508.200'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E05.318', 'N06.850.520'], ['C23.550.291.687.500', 'G05.38... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Inhibition by aspirin of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide initiation and sodium saccharin promotion of urinary bladder carcinogenesis in male F344 rats. | N-[4-(5-Nitro-2-furyl)-2-thiazolyl]formamide (FANFT) is metabolically activated by several enzyme systems, including prostaglandin H synthase. Aspirin is an inhibitor of prostaglandin H synthase and has been shown to inhibit FANFT-induced bladder carcinogenesis when coadministered in the diet. To further evaluate the e... | ['Animals', 'Aspirin', 'Body Weight', 'Cocarcinogenesis', 'FANFT', 'Hydrogen-Ion Concentration', 'Male', 'Rats', 'Rats, Inbred F344', 'Saccharin', 'Thiazoles', 'Urinary Bladder Neoplasms'] | 3,731,063 | [['B01.050'], ['D02.455.426.559.389.657.410.595.176'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['C04.697.098.875', 'C23.550.727.098.750'], ['D02.640.600.290', 'D02.886.675.250', 'D03.383.129.708.250', 'D03.383.312.649.290'], ['G02.300'], ['B01... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The value of cone beam CT in assessing and managing a dilated odontome of a maxillary canine. | A case of an unusual anomaly in a maxillary canine is described. A deep enamel invagination resulted in pulpal necrosis, longstanding infection and development of an associated radicular cyst. Diagnostic X-ray imaging was invaluable in demonstrating the complex root anatomy of the dilated odontome. In particular, a con... | ['Adolescent', 'Cone-Beam Computed Tomography', 'Cuspid', 'Dental Enamel', 'Dental Pulp Necrosis', 'Humans', 'Imaging, Three-Dimensional', 'Male', 'Maxillary Diseases', 'Patient Care Planning', 'Periapical Abscess', 'Radicular Cyst', 'Radiography, Bitewing', 'Tooth Root'] | 26,058,225 | [['M01.060.057'], ['E01.370.350.700.810.810.490', 'E01.370.350.825.810.810.399'], ['A14.549.167.860.200'], ['A14.549.167.900.255'], ['C07.793.237.315', 'C23.550.717.182'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.400', 'L01.224.308.410'], ['C05.500.693', 'C07.320.660'], ['N04.590.233.624'], ['C01.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Ultrastructural features of ichthyosis hystrix strongly resembling Lambert type. | Ichthyosis hystrix (IH) is characterized by spiny hyperkeratotic scale, and includes Brocq type, Lambert type, Curth-Macklin type, Rheydt type and B?fverstedt type. The first documented cases of familial IH were of Lambert type. However, the ultrastructural features of IH Lambert type have not been reported. Three pati... | ['Adolescent', 'China', 'Female', 'Humans', 'Ichthyosis', 'Male', 'Microscopy, Electron', 'Skin'] | 17,355,236 | [['M01.060.057'], ['Z01.252.474.164'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.131.831.512', 'C16.614.492', 'C17.800.428.333', 'C17.800.804.512'], ['E01.370.350.515.402', 'E05.595.402'], ['A17.815']] | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
IL-6 and CD8+ T cell counts combined are an early predictor of in-hospital mortality of patients with COVID-19. | BACKGROUNDFatal cases of COVID-19 are increasing globally. We retrospectively investigated the potential of immunologic parameters as early predictors of COVID-19.METHODSA total of 1018 patients with confirmed COVID-19 were enrolled in our 2-center retrospective study. Clinical feature, laboratory test, immunological t... | ['Aged', 'Area Under Curve', 'Betacoronavirus', 'CD8-Positive T-Lymphocytes', 'COVID-19', 'Coronavirus Infections', 'Female', 'Hospital Mortality', 'Humans', 'Interleukin-10', 'Interleukin-6', 'Interleukin-8', 'Logistic Models', 'Lymphocyte Count', 'Lymphopenia', 'Male', 'Middle Aged', 'Multivariate Analysis', 'Pandemi... | 32,544,099 | [['M01.060.116.100'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['B04.820.578.500.540.150.113'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['C01.748.214', 'C01.748.610.763.500', 'C01.925.705.500', 'C01.925.782.600.550.200.163',... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Elderly wards and their legal guardians: analysis of county probate records in Ohio and Washington. | We examined the demographic profiles of older wards and their guardians in Ohio and Washington states. The adjudication process, as experienced by older persons placed in legal guardianship, was also explored. Findings suggest that current state statutes of guardianship as they pertain to elders may not be feasible or ... | ['Aged', 'Aged, 80 and over', 'Demography', 'Female', 'Humans', 'Jurisprudence', 'Legal Guardians', 'Male', 'Middle Aged', 'Ohio', 'Washington'] | 2,044,987 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.604.583', 'N03.706.535'], ['M01.380'], ['M01.060.116.630'], ['Z01.107.567.875.075.512', 'Z01.107.567.875.350.540', 'Z01.107.567.875.510.540'], ['Z01.107.567.875.560.900', ... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Evaluation of a diversity intervention funded by Title VII. | PURPOSE: The purpose of this study was to evaluate an intervention intended to make an impact in heightening the cultural training of health care-focused high school and physician assistant (PA) students, increasing the number of underrepresented minority faculty and preceptors, and increasing the number of minority/di... | ['Adolescent', 'Adult', 'Career Choice', 'Cultural Competency', 'Cultural Diversity', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Physician Assistants', 'Program Evaluation'] | 21,366,110 | [['M01.060.057'], ['M01.060.116'], ['F02.463.785.373.346.400'], ['I01.880.853.100.364'], ['I01.076.201.450.350', 'I01.880.853.100.450'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.526.485.067.740', 'N02.360.067.740'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Landscape history, fragmentation, and patch occupancy: models for a forest bird with limited dispersal. | We developed and tested patch occupancy models for an endemic understory bird with limited dispersal ability, the Chucao Tapaculo (Scelorchilus rubecula), in two South American temperate rain forest landscapes that differed in levels and duration of forest loss. We assessed cover changes since 1961 in each landscape an... | ['Animals', 'Chile', 'Conservation of Natural Resources', 'Ecosystem', 'Models, Biological', 'Passeriformes', 'Reproducibility of Results', 'Trees'] | 17,205,900 | [['B01.050'], ['Z01.107.757.235'], ['J01.256', 'N06.230.080'], ['G16.500.275.157', 'N06.230.124'], ['E05.599.395'], ['B01.050.150.900.248.620'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['B01.650.915']] | ['Organisms [B]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
Hyperlipidaemia during normal pregnancy, parturition and lactation. | Excessive accumulation of one or more of the major lipids in plasma can produce a marked increase in the risk of coronary heart diseases and other vascular complications. During and after pregnancy, changes in the levels of total cholesterol, triglyceride, low density lipoprotein-cholesterol, and high density lipoprote... | ['Adult', 'Age Factors', 'Breast Feeding', 'Cholesterol', 'Cholesterol, HDL', 'Cholesterol, LDL', 'Female', 'Fetus', 'Humans', 'Hyperlipidemias', 'Lactation', 'Lipoproteins', 'Parity', 'Postpartum Period', 'Pregnancy', 'Pregnancy Complications', 'Pregnancy Trimesters', 'Puerperal Disorders', 'Risk Factors', 'Sex Factor... | 10,497,670 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['D04.210.500.247.222.284', 'D04.210.500.247.808.197', 'D10.570.938.208'], ['D04.210.500.247.808.197.238', 'D10.532.432.400', 'D10.570.938.208.270', 'D12.776.521.479.470'],... | ['Named Groups [M]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Risk factors of lower limb cellulitis in a level-two healthcare facility in Cameroon: a case-control study. | BACKGROUND: Cellulitis is a common infection of the skin and subcutaneous tissues. It is associated with significant morbidity from necrosectomies and amputations especially in sub-Saharan Africa. We aimed at identifying the risk factors and burden of lower limb cellulitis to inform preventive strategies in Cameroon.ME... | ['Adult', 'Aged', 'Cameroon', 'Case-Control Studies', 'Cellulitis', 'Edema', 'Female', 'Fever', 'Humans', 'Length of Stay', 'Lower Extremity', 'Male', 'Middle Aged', 'Odds Ratio', 'Risk Factors', 'Streptococcal Infections', 'Streptococcus'] | 28,606,058 | [['M01.060.116'], ['M01.060.116.100'], ['Z01.058.290.100.110'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C01.800.130', 'C01.830.200', 'C17.300.185', 'C23.550.470.756.200'], ['C23.888.277'], ['C23.888.119.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.760.400.480', ... | ['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A profiling study of a newly developed HCVcc strain PR63cc's sensitivity to direct-acting antivirals. | The development of direct-acting antivirals (DAAs) has significantly improved hepatitis C virus (HCV) treatment. However, drug resistance remains a potential concern in the real-world DAA-based therapies. We previously developed a novel full-length genotype 2a HCVcc clone PR63cc directly from clinical isolates. Here in... | ['Adenosine', 'Antiviral Agents', 'Drug Discovery', 'Drug Resistance, Viral', 'Enzyme Inhibitors', 'Genotype', 'Hepacivirus', 'Hepatitis C, Chronic', 'Humans', 'Imidazoles', 'Isoquinolines', 'Mutation', 'Sofosbuvir', 'Sulfonamides'] | 28,025,084 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['D27.505.954.122.388'], ['E05.295', 'H01.158.703.007.675', 'H01.181.466.675'], ['G06.225.420', 'G06.920.225', 'G07.690.773.984.269.420'], ['D27.505.519.389'], ['G05.380'], ['B04.450.380', 'B04.820.578.344.475'], ['C01.221.250.750.120', 'C01.925.440.44... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of turbidity on the spontaneous and prey-searching activity of juvenile Atlantic cod (Gadus morhua). | Increasing turbidity in coastal waters in the North Atlantic and adjacent seas has raised concerns about impacts on Atlantic cod (Gadus morhua) using these areas as nurseries. A previous experiment (Meager et al. 2005 Can. J. Fish. Aquat. Sci. 62, 1978-1984) has shown that turbidity (up to 28 beam attenuation m-1) had ... | ['Animals', 'Gadus morhua', 'Motor Activity', 'Nephelometry and Turbidimetry', 'Predatory Behavior', 'Swimming', 'Time Factors', 'Video Recording'] | 17,472,920 | [['B01.050'], ['B01.050.150.900.493.467.400'], ['F01.145.632', 'G11.427.410.698'], ['E05.196.712.650'], ['F01.145.113.111.600', 'F01.145.113.252.520'], ['G11.427.410.568.800', 'G11.427.410.698.277.875', 'I03.350.875', 'I03.450.642.845.945.500'], ['G01.910.857'], ['L01.280.960']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
Reduced Thigh Pain with Short Femoral Stem Design Following Direct Anterior Primary Total Hip Arthroplasty. | BACKGROUND: Thigh pain is a variably reported symptom in the postoperative period following primary total hip arthroplasty (THA) with a well-fixed cementless femoral implant. While research has identified stem size, stem alignment, and differences in modulus of elasticity between implant and host bone as potential sour... | ['Arthroplasty, Replacement, Hip', 'Hip Joint', 'Hip Prosthesis', 'Humans', 'Pain, Postoperative', 'Prosthesis Design', 'Thigh', 'Treatment Outcome'] | 31,037,711 | [['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['A02.835.583.411'], ['E07.695.400.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.767.700', 'C23.888.592.612.832'], ['E05.320.550', 'E07.695.680'], ['A01.378.610.750'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Phylogenetic analysis of a novel H6N6 avian influenza virus isolated from a green peafowl in China and its pathogenic potential in mice. | To explore the ecology of the H6 subtype avian influenza viruses in Hebei Province, China, a long-term surveillance was conducted in 2012 among domestic poultry and birds in a wildlife park. In this study, we report the characterization of a novel H6N6 avian influenza virus isolated from a healthy green peafowl in Qing... | ['Animals', 'China', 'Female', 'Genetic Variation', 'Genome, Viral', 'Hemagglutinin Glycoproteins, Influenza Virus', 'Influenza A virus', 'Influenza in Birds', 'Mice', 'Neuraminidase', 'Orthomyxoviridae Infections', 'Phylogeny', 'Poultry', 'Sequence Analysis, DNA', 'Viral Proteins'] | 25,220,620 | [['B01.050'], ['Z01.252.474.164'], ['G05.365'], ['G05.360.340.358.840'], ['D12.776.964.970.880.345.500'], ['B04.820.480.968.405.400'], ['C01.925.782.620.300', 'C22.131.450'], ['B01.050.150.900.649.313.992.635.505.500'], ['D08.811.277.450.692'], ['C01.925.782.620'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['B01.050.0... | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 |
Toddlers' sleep and temperament: reporting bias or a valid link? A research note. | Objective sleep measures derived from a computerized movement detector attached to the child's leg, were obtained for a group of 31 toddlers (mean age: 18.5 months). The monitored sleep parameters were compared with maternal assessment of the child's sleep and her perception of his temperament. The validity of maternal... | ['Child, Preschool', 'Circadian Rhythm', 'Female', 'Humans', 'Infant', 'Male', 'Mothers', 'Personality Assessment', 'Sleep Stages', 'Temperament'] | 1,400,706 | [['M01.060.406.448'], ['G07.180.562.190'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F01.829.263.500.320.200', 'I01.880.853.150.500.340.270', 'M01.620.630'], ['F04.513'], ['F02.830.855.796', 'G11.561.803.754'], ['F01.752.898']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Voice quality after laser surgery or radiotherapy for T1a glottic carcinoma. | OBJECTIVE: To compare the effect on phonation of radiotherapy and endoscopic laser surgery for stage T1a glottic squamous cell carcinoma.STUDY DESIGN: Retrospective.METHODS: Patients treated for stage T1a glottic carcinoma from August 1994 to March 2000 and who had been followed for at least 1 year were candidates. Eig... | ['Aged', 'Aged, 80 and over', 'Carcinoma, Squamous Cell', 'Combined Modality Therapy', 'Humans', 'Laser Therapy', 'Male', 'Middle Aged', 'Neoplasm Staging', 'Phonetics', 'Severity of Illness Index', 'Tongue', 'Tongue Neoplasms', 'Voice Disorders', 'Voice Quality'] | 12,792,332 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.594', 'E04.014.520'], ['M01.060.116.630'], ['E01.789.625'], ['L01.559.598.518'], ['E05.318.308.980.438.475.456.500', 'N05.715.360.300.800.438.375.364.500', '... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Health Care [N]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Social and family dynamic with patients with definitive intestinal ostomy. | RATIONAL: The person who undergoes a definitive intestinal ostomy experience significant changes in social and family dynamics. Most of the time the patients are fragile by risk due to the new situation.AIM: To analyze the social dynamics of people with permanent intestinal stoma.METHOD: Qualitative research on the bas... | ['Aged', 'Aged, 80 and over', 'Enterostomy', 'Family Relations', 'Female', 'Humans', 'Interpersonal Relations', 'Male', 'Middle Aged'] | 24,190,372 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.210.338', 'E04.579.338'], ['F01.829.263.370', 'I01.880.853.150.439'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.401'], ['M01.060.116.630']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Restoration of impaired immune functions in aging animals. IV. Action of 2-mercaptoethanol in enhancing age-reduced immune responsiveness. | The enhancing effect of 2-mercaptoethanol (2-ME) on the immune responses of young and old unseparated spleen cells and purified populations of T-cells, B-cells and macrophages was studied. While 2-ME enhances both the normal responses of young cells and the age-reduced responses of old cells, the sulfhydryl compound ha... | ['Aging', 'Animals', 'Antibody Formation', 'B-Lymphocytes', 'Concanavalin A', 'Female', 'Lymphocyte Activation', 'Male', 'Mercaptoethanol', 'Mice', 'Phytohemagglutinins', 'Spleen', 'T-Lymphocytes'] | 6,969,335 | [['G07.345.124'], ['B01.050'], ['G12.450.050.370.250'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565']... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Healing the orphaned heart: heart failure in a patient with glucose-6-phosphate dehydrogenase deficiency. | Patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency are not represented in clinical trials for heart failure. Moreover, many of the recommended medications can cause haemolysis in this group of patients. We present the case of a 71-year-old woman with G6PD deficiency admitted for acute non-ischemic heart ... | ['Aged', 'Diuretics', 'Drug Therapy, Combination', 'Ethacrynic Acid', 'Female', 'Glucosephosphate Dehydrogenase Deficiency', 'Heart Failure', 'Humans', 'Losartan', 'Metoprolol', 'Spironolactone'] | 25,743,872 | [['M01.060.116.100'], ['D27.505.696.560.500'], ['E02.319.310'], ['D02.241.081.018.386.682.300', 'D02.241.511.316.682.200'], ['C15.378.071.141.150.480', 'C16.320.070.480', 'C16.320.565.202.402', 'C18.452.648.202.402'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.455.426.559.389.185.475', 'D03... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The distribution of secretory immunoglobulin A in the intrahepatic biliary epithelium of patients with hepatolithiasis. | In the treatment of hepatolithiasis, liver resection helps to prevent recurrence and may reduce the incidence of infection by removal of the atrophic tissue. This study was conducted to determine if the affected liver tissue in hepatolithiasis is inflamed or has lowered local immunity by examining the distribution of s... | ['Bile Ducts, Intrahepatic', 'Cholangitis', 'Cholelithiasis', 'Epithelium', 'Humans', 'Immunoglobulin A, Secretory', 'Proliferating Cell Nuclear Antigen'] | 7,865,966 | [['A03.159.183.158', 'A03.620.150'], ['C06.130.120.200'], ['C06.130.409'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.124.486.485.114.619.026.030', 'D12.776.124.790.651.114.619.026.030', 'D12.776.377.715.548.114.619.026.030'], ['D12.776.660.740', 'D23.050.290.750', 'D23.101.140.600']] | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Biopharmaceutical study of aminophenazone-containing suppositories. 2. Results of in vitro drug release and in vivo drug absorption]. | Ten kinds of surface active ingredients of Th. Goldschmidt AG. (Essen-FRG) in concentrations of 5% were mixed with Witepsol W 35 and Massa Estarinum 299 suppository masses of H?ls-Troisdorf AG. Werk (Witten-FRG) which are official in Hungary. According to the authors the above tensides, which have been used advantageou... | ['Aminopyrine', 'Animals', 'Diffusion', 'Intestinal Absorption', 'Suppositories'] | 2,239,342 | [['D03.383.129.539.850.077'], ['B01.050'], ['G01.202', 'G02.196'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500', 'G07.690.725.015.500.374.500', 'G10.261.353.500'], ['D26.255.785']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Disentangling criminal profiling: accuracy, homology, and the myth of trait-based profiling. | The scholarly literature over the past decade has chronicled a growing problem in the forensic technique colloquially called criminal profiling. The basis of this conundrum appears to originate from a concept referred to as "offender homology," which presumes an inherent uniformity among offenders that is believed to u... | ['Criminal Psychology', 'Humans', 'Personality'] | 24,335,847 | [['F02.784.240'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752']] | ['Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Molecular structure and vibrational analysis of 3-Ethylpyridine using ab initio HF and density functional theory (B3LYP) calculations. | The FT-Raman and FT-IR spectra for 3-Ethylpyridine (3-EP) have been recorded in the region 4000-100 cm(-1) and compared with the harmonic vibrational frequencies calculated using HF/DFT (B3LYP) method by employing 6-31G(d,p) and 6-311++G(d,p) basis set with appropriate scale factors. IR intensities and Raman activities... | ['Models, Chemical', 'Models, Molecular', 'Molecular Conformation', 'Pyridines', 'Quantum Theory', 'Spectroscopy, Fourier Transform Infrared', 'Spectrum Analysis, Raman', 'Vibration'] | 21,183,400 | [['E05.599.495'], ['E05.599.595'], ['G02.111.570.820'], ['D03.383.725'], ['H01.671.579.800'], ['E05.196.712.726.676.700', 'E05.196.867.826.676.700'], ['E05.196.822.860', 'E05.196.867.890'], ['G01.374.930']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of oxiracetam in plasma and urine by column-switching high-performance liquid chromatography. | A column-switching high-performance liquid chromatographic method was developed for the determination of oxiracetam in plasma and urine. A sample of plasma (250 microliters) or urine (10 microliters) is mixed with the internal standard solution, 4.2 ml of acetonitrile-water (1000:4, v/v) and 0.8 ml of dichloromethane, ... | ['Chemical Phenomena', 'Chemistry', 'Chromatography, High Pressure Liquid', 'Humans', 'Pyrrolidines', 'Spectrophotometry, Ultraviolet'] | 2,625,458 | [['G02'], ['H01.181'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.383.773'], ['E05.196.712.726.802', 'E05.196.867.826.802']] | ['Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Transgenic mice overexpressing glutathione peroxidase are resistant to myocardial ischemia reperfusion injury. | To test the authors' hypothesis that cellular antioxidant enzymes constitute a cellular defense against acute stress, myocardial ischemia reperfusion injury in transgenic mice overexpressing the cellular glutathione peroxidase (GSHPx-1) was studied. Transgenic mice were generated using the entire mouse GSHPx-1 gene inc... | ['Analysis of Variance', 'Animals', 'Brain', 'Creatine Kinase', 'Gene Expression Regulation, Enzymologic', 'Glutathione Peroxidase', 'Lung', 'Mice', 'Mice, Transgenic', 'Muscles', 'Myocardial Infarction', 'Myocardial Reperfusion Injury', 'Myocardium', 'Organ Specificity'] | 8,877,785 | [['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['B01.050'], ['A08.186.211'], ['D08.811.913.696.640.150'], ['G05.308.320'], ['D08.811.682.732.500'], ['A04.411'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.992.635.505.500.800'], ['A02.633', 'A10.690'... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of strain measurement from multimodality tissue tracking with strain-encoding MRI and harmonic phase MRI in pulmonary hypertension. | BACKGROUND: Pixel-based multimodality tissue tracking (MTT) is a new noninvasive method for the quantification of cardiac deformation from cine image of MRI. The aim of this study is to validate bi-ventricular strain measurement by MTT compared to strain-encoding (SENC) MRI and harmonic phase (HARP) MRI in pulmonary hy... | ['Female', 'Heart Ventricles', 'Humans', 'Hypertension, Pulmonary', 'Magnetic Resonance Imaging, Cine', 'Male', 'Middle Aged', 'Myocardial Contraction', 'Reproducibility of Results', 'Ventricular Function, Right'] | 25,590,963 | [['A07.541.560'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.423', 'C14.907.489.556'], ['E01.370.350.825.500.510'], ['M01.060.116.630'], ['G09.330.580', 'G11.427.494.570'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['G09.330.955.900']] | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
"Diminishing returns" in the scaling of functional leaf traits across and within species groups. | More than 5,000 measurements from 1,943 plant species were used to explore the scaling relationships among the foliar surface area and the dry, water, and nitrogen/phosphorus mass of mature individual leaves. Although they differed statistically, the exponents for the relationships among these variables were numericall... | ['Plant Leaves', 'Water'] | 17,502,616 | [['A18.024.812'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enzyme feeding strategies for better fed-batch enzymatic hydrolysis of empty fruit bunch. | Lignin inhibitory becomes a major obstacle for enzymatic hydrolysis of empty fruit bunch conducted in high solid loading. Since current technology required high enzyme loading, surfactant application could not effectively used since it is only efficient in low enzyme loading. In addition, it will increase final operati... | ['Arecaceae', 'Batch Cell Culture Techniques', 'Cellulase', 'Cellulose', 'Fruit', 'Hydrolysis', 'Lignin', 'Polysaccharides', 'Steam'] | 26,881,335 | [['B01.650.940.800.575.912.250.093'], ['E05.481.500.249.124'], ['D08.811.277.450.420.200.200'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['G02.380'], ['D05.750.078.562.180.515', 'D05.750.078.687', 'D20.538', 'D25.720.099... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Esthetic outcomes with porcelain-fused-to-ceramic and all-ceramic single-implant crowns: a randomized clinical trial. | OBJECTIVES: the aim of this randomized-controlled clinical trial was to compare the objective and subjective esthetic outcomes of two types of screwed-retained single-implant crowns.MATERIALS AND METHODS: participants were randomly assigned to the test (all-ceramic) and control [porcelain-fused-to-ceramic (PFM)] groups... | ['Crowns', 'Dental Implants, Single-Tooth', 'Dental Models', 'Dental Porcelain', 'Dental Prosthesis Design', 'Dental Prosthesis, Implant-Supported', 'Double-Blind Method', 'Esthetics, Dental', 'Humans', 'Incisor', 'Jaw, Edentulous', 'Maxilla', 'Metal Ceramic Alloys', 'Patient Satisfaction', 'Prospective Studies', 'ROC ... | 21,158,931 | [['E06.780.346.250', 'E07.695.190.088'], ['E06.780.346.593.185', 'E07.695.185.185'], ['E06.261', 'J01.897.280.500.545.129.200', 'L01.178.820.090.545.129.200'], ['D25.339.376', 'J01.637.051.339.376', 'J01.637.153.377'], ['E06.780.346.625', 'E06.912.145'], ['E06.780.346.706', 'E07.695.190.185'], ['E05.318.370.300', 'E05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
The identification and characterization of a STAT5 gene signature in hematologic malignancies. | BACKGROUND: The JAK-STAT pathway is an important signaling pathway downstream of multiple cytokine and growth factor receptors. Dysregulated JAK-STAT signaling has been implicated in the pathogenesis of multiple human malignancies.OBJECTIVE: Given this pivotal role of JAK-STAT dysregulation, it is important to identify... | ['Animals', 'Cell Line, Tumor', 'Female', 'Hematologic Neoplasms', 'Heterografts', 'Humans', 'Janus Kinases', 'Mice', 'Mice, Inbred NOD', 'Mice, SCID', 'Pyrazoles', 'STAT5 Transcription Factor', 'Signal Transduction'] | 25,524,945 | [['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['C04.588.448', 'C15.378.400'], ['A01.941.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.913.696.620.682.725.124', 'D12.776.476.393'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.565', 'B01.050.150.900.649.313.992.635.50... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Poly(D,L-Lactide-Co-Glycolide) Tubes With Multifilament Chitosan Yarn or Chitosan Sponge Core in Nerve Regeneration. | PURPOSE: The influence of different kinds of nerve guidance conduits on regeneration of totally transected rat sciatic nerves through a 7-mm gap was examined.MATERIALS AND METHODS: Five different types of conduits made of chitosan and poly(D,L-lactide-co-glycolide) (PLGA) were constructed and tested in vivo. We divided... | ['Animals', 'Chitosan', 'Guided Tissue Regeneration', 'Lactic Acid', 'Male', 'Nerve Regeneration', 'Outcome Assessment, Health Care', 'Peripheral Nerve Injuries', 'Polyglycolic Acid', 'Polylactic Acid-Polyglycolic Acid Copolymer', 'Rats', 'Rats, Wistar', 'Sciatic Nerve', 'Tissue Scaffolds'] | 27,542,542 | [['B01.050'], ['D05.750.078.139.500', 'D09.698.211.500'], ['E04.680.300'], ['D02.241.511.459.450'], ['G11.561.585', 'G16.762.611'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['C10.668.829.712', 'C10.900.575', 'C26.915.650'], ['D05.750.728.780', 'D25.720.728.780', 'J01.637.051.720.728.780'], ['D... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
Palmitoylethanolamide normalizes intestinal motility in a model of post-inflammatory accelerated transit: involvement of CB₁ receptors and TRPV1 channels. | BACKGROUND AND PURPOSE: Palmitoylethanolamide (PEA), a naturally occurring acylethanolamide chemically related to the endocannabinoid anandamide, interacts with targets that have been identified in peripheral nerves controlling gastrointestinal motility, such as cannabinoid CB1 and CB2 receptors, TRPV1 channels and PPA... | ['Amides', 'Animals', 'Colitis', 'Disease Models, Animal', 'Ethanolamines', 'Gastrointestinal Motility', 'Inflammation', 'Injections, Intraperitoneal', 'Irritable Bowel Syndrome', 'Male', 'Mice', 'Mice, Inbred ICR', 'Mustard Plant', 'Palmitic Acids', 'Piperidines', 'Plant Oils', 'Pyrazoles', 'RNA, Messenger', 'Receptor... | 24,818,658 | [['D02.065'], ['B01.050'], ['C06.405.205.265', 'C06.405.469.158.188'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['D02.033.100.291', 'D02.033.375.291', 'D02.092.063.291'], ['G10.261.360'], ['C23.550.470'], ['E02.319.267.530.490'], ['C06.405.469.158.272.608'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The reversible change in the redox state of type I Cu in Myrothecium verrucaria bilirubin oxidase depending on pH. | The redox state of type I Cu in Myrothecium verrucaria bilirubin oxidase (BO), a multicopper oxidase utilized in the clinical investigation of liver, is an equilibrium state of the oxidized and reduced forms, reflected in the reversible absorption and electron paramagnetic resonance (EPR) spectral changes depending on ... | ['Copper', 'Electron Spin Resonance Spectroscopy', 'Fungal Proteins', 'Hydrogen-Ion Concentration', 'Oxidation-Reduction', 'Oxidoreductases Acting on CH-CH Group Donors'] | 15,388,981 | [['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['E05.196.867.519.274'], ['D12.776.354'], ['G02.300'], ['G02.700', 'G03.295.531'], ['D08.811.682.660']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hemodialysis-associated pseudoporphyria resistant to N-acetylcysteine. | We report a 33-year-old female patient who had hemodialysis-associated pseudoporphyria which did not respond to treatment with oral N-acetylcysteine. She responded favorably to treatment with the anti-malarial drug, chloroquine. The case is being reported to highlight the difficulty in interpreting the urinary porphyri... | ['Acetylcysteine', 'Administration, Oral', 'Adult', 'Chloroquine', 'Drug Resistance', 'Female', 'Humans', 'Kidney Failure, Chronic', 'Porphyrias', 'Renal Dialysis', 'Skin', 'Treatment Failure'] | 21,422,632 | [['D02.886.030.230.259', 'D12.125.166.230.259'], ['E02.319.267.100'], ['M01.060.116'], ['D03.633.100.810.050.180'], ['G07.690.773.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['C18.452.811'], ['E02.870.300', 'E02.912.800'], ['A17.815'], ['E01.789.80... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Antifungal compounds from the rhizome and roots of Ferula hermonis. | The antifungal activity of hexane, dichloromethane, methanol and aqueous extracts from the rhizome and root of Ferula hermonis was assayed in vitro by the agar disk diffusion method against a panel of human opportunistic and pathogenic fungi. Among them, the hexane and dichloromethane extracts showed the highest activi... | ['Antifungal Agents', 'Arthrodermataceae', 'Benzoates', 'Bridged Bicyclo Compounds', 'Candida', 'Cycloheptanes', 'Ferula', 'Microbial Sensitivity Tests', 'Microsporum', 'Plant Extracts', 'Plant Oils', 'Plant Roots', 'Rhizome', 'Sesquiterpenes', 'Trichophyton'] | 22,927,102 | [['D27.505.954.122.136'], ['B01.300.107.650.080'], ['D02.241.223.100', 'D02.455.426.559.389.127'], ['D02.455.426.100.080', 'D04.075.080'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['D02.455.426.392.368.284'], ['B01.650.940.800.575.912.250.075.300'], ['E01.370.225.875.595', 'E05.200.875.595', 'E05.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spread of Alsidium corallinum C. Ag. in a Tyrrhenian eutrophic lagoon dominated by opportunistic macroalgae. | In 2007, the Rhodophyceae Alsidium corallinum C. Ag., a marine taxon, bloomed in the eutrophic lagoon of Orbetello (Tuscany, Italy) for the first time, becoming the dominant species in spring and summer. In November, its biomass collapsed. The hypothesis examined in this study is that the bloom expressed a relatively l... | ['Biomass', 'Ecosystem', 'Environmental Monitoring', 'Eutrophication', 'Italy', 'Nitrogen', 'Phosphorus', 'Rhodophyta', 'Seasons', 'Seaweed', 'Water Pollution, Chemical'] | 23,137,555 | [['G16.500.275.157.100', 'N06.230.124.100'], ['G16.500.275.157', 'N06.230.124'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G16.500.285'], ['Z01.542.489'], ['D01.268.604', 'D01.362.625'], ['D01.268.666'], ['B01.650.700'], ['G01.910.645.661', 'G16.500.275.071.590', 'N06.230.300.100.250.525'], ['B05.080.750'], ['N06.8... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
ECM remodelling components regulated during jaw periosteal cell osteogenesis. | Human JPCs (jaw periosteal cells) are a promising source for the engineering of cell-based osteoinductive grafts in oral surgery. For this purpose, cell characteristics of this stem cell source should be elucidated in detail. Analysis of gene expression profiles may help us to evaluate key factors and cellular targets ... | ['Bone Morphogenetic Protein 2', 'Calcium', 'Cells, Cultured', 'Collagen', 'Extracellular Matrix', 'GPI-Linked Proteins', 'Gene Expression Profiling', 'Humans', 'Oligonucleotide Array Sequence Analysis', 'Osteogenesis', 'Periosteum', 'Proteome', 'Tissue Inhibitor of Metalloproteinases', 'Up-Regulation'] | 21,524,278 | [['D12.644.276.954.200.200', 'D12.776.467.942.200.200', 'D23.529.942.200.200'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['A11.251'], ['D05.750.078.280', 'D12.776.860.300.250'], ['A11.284.295.310'], ['D12.776.395.550.448', 'D12.776.543.484.500', 'D12.776.543.550.418'], ['E05.393.332'], ['B01.050.150.900.6... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prenatal detection of aneuploidies using fluorescence in situ hybridization: a preliminary experience in an Indian set up. | Fluorescence in situ hybridization (FISH) is a powerful molecular cytogenetic technique which allows rapid detection of aneuploidies on interphase cells and metaphase spreads. The aim of the present study was to evaluate FISH as a tool in prenatal diagnosis of aneuploidies in high risk pregnancies in an Indian set up. ... | ['Adult', 'Amniotic Fluid', 'Aneuploidy', 'Chorionic Villi Sampling', 'Female', 'Humans', 'In Situ Hybridization, Fluorescence', 'India', 'Karyotyping', 'Male', 'Pregnancy', 'Prenatal Diagnosis'] | 11,937,686 | [['M01.060.116'], ['A12.098', 'A16.378.149'], ['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['E01.370.225.500.384.100.149', 'E01.370.225.998.054.149', 'E01.370.378.630.150', 'E01.370.388.100.150', 'E04.074.149', 'E05.200.500.384.100.149', 'E05.200.998.054.149', 'E05.242.384.100.149'], ['B01.050.150.900.649... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Improved functional recovery of the isolated rat heart after 24 hours of hypothermic arrest with a stable prostacyclin analogue (ZK 36 374). | Prostacyclin (PGI2) can protect the heart against ischemia, i.e. it can reduce myocardial damage [9, 10]. PGI2 protects the myocardium in vivo by preventing platelets from clumping and by dispersing preformed platelet aggregates [1,14]. However, also in the absence of platelets, PGI2 was shown to protect the myocardium... | ['Animals', 'Arrhythmias, Cardiac', 'Cardiovascular Agents', 'Coronary Circulation', 'Coronary Disease', 'Electrophysiology', 'Epoprostenol', 'Heart', 'Heart Arrest', 'Hypothermia, Induced', 'Iloprost', 'Male', 'Rats', 'Rats, Inbred Strains'] | 6,197,528 | [['B01.050'], ['C14.280.067', 'C23.550.073'], ['D27.505.954.411'], ['G09.330.100.324'], ['C14.280.647.250', 'C14.907.585.250'], ['H01.158.344.528', 'H01.158.782.236'], ['D10.251.355.255.550.550.500', 'D23.469.050.175.725.550.500'], ['A07.541'], ['C14.280.383'], ['E02.258.750'], ['D10.251.355.255.550.775.125', 'D23.469.... | ['Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Associations Between Systemic and Local Corticosteroid Use With Metabolic Syndrome and Body Mass Index. | Context: Use of systemic corticosteroids (CSs) may induce adverse cardiometabolic alterations, potentially leading to obesity and metabolic syndrome (MetS). Although evidence is accumulating that local CSs have considerable systemic effects, their effects on cardiometabolic factors in the general population remain uncl... | ['Adult', 'Body Mass Index', 'Cohort Studies', 'Cross-Sectional Studies', 'Drug Administration Routes', 'Female', 'Glucocorticoids', 'Humans', 'Male', 'Metabolic Syndrome', 'Middle Aged', 'Netherlands', 'Obesity', 'Risk Factors', 'Waist Circumference'] | 28,973,553 | [['M01.060.116'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E02.319.267'], ['D06.472.040.543', 'D27.505.696.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Carcinogenicity in mice of some fatty acid methyl esters. 2. Peroral and subcutaneous application. | Two fatty acid methyl esters, methyl oleate and methyl 12-oxo-trans-10-octadecenoate, have been tested for carcinogenicty by oral and subcutaneous administration in ST/a mice of both sexes. A positive effect of methyl oleate could not be assessed, while the results pointed to a promoter effect of methyl oxo-octadecenoa... | ['4-Nitroquinoline-1-oxide', '9,10-Dimethyl-1,2-benzanthracene', 'Administration, Oral', 'Animals', 'Carcinogens', 'Female', 'Injections, Subcutaneous', 'Male', 'Mice', 'Neoplasms, Experimental', 'Oleic Acids', 'Papilloma', 'Sarcoma, Experimental', 'Skin Neoplasms', 'Stearic Acids', 'Stomach Neoplasms', 'Time Factors'] | 809,992 | [['D02.640.820.600', 'D03.633.100.810.470.450', 'D03.661.243.500'], ['D02.455.426.559.847.149.301', 'D04.615.149.301'], ['E02.319.267.100'], ['B01.050'], ['D27.888.569.100'], ['E02.319.267.530.620'], ['B01.050.150.900.649.313.992.635.505.500'], ['C04.619', 'E05.598.500.496'], ['D10.251.355.325.600'], ['C04.557.470.700.... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Participant satisfaction with clinical trial experience and post-trial transitioning to HIV care in Kenya. | We conducted an exploratory analysis of former HIV Prevention Trials Network 052 (HPTN 052) clinical trial participants in 2016 to assess their (1) satisfaction with the HPTN 052 clinical trial care and treatment, and reasons for joining the trial; and (2) perspectives about the post-trial transition to public HIV care... | ['Adolescent', 'Adult', 'Anti-Retroviral Agents', 'Biomedical Research', 'Continuity of Patient Care', 'Female', 'Focus Groups', 'HIV Infections', 'Health Services Accessibility', 'Humans', 'Interviews as Topic', 'Male', 'Middle Aged', 'Personal Satisfaction', 'Program Evaluation', 'Qualitative Research', 'Young Adult'... | 30,157,702 | [['M01.060.057'], ['M01.060.116'], ['D27.505.954.122.388.077'], ['H01.770.644.145'], ['E02.760.169', 'N02.421.585.169', 'N04.590.233.727.210'], ['E05.318.308.112', 'N05.715.360.300.269', 'N06.850.520.308.112'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', '... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 |
A-type and T-type currents interact to produce a novel spike latency-voltage relationship in cerebellar stellate cells. | The modification of first-spike latencies by low-threshold and inactivating K+ currents (IA) have important implications in neuronal coding and synaptic integration. To date, cells in which first-spike latency characteristics have been analyzed have shown that increased hyperpolarization results in longer first-spike l... | ['Action Potentials', 'Animals', 'Calcium Channels', 'Cerebellum', 'Electric Conductivity', 'Kinetics', 'Models, Neurological', 'Neurons', 'Patch-Clamp Techniques', 'Potassium Channels', 'Rats', 'Rats, Sprague-Dawley', 'Reaction Time'] | 16,306,399 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['D12.776.157.530.400.150', 'D12.776.543.550.450.150', 'D12.776.543.585.400.150'], ['A08.186.211.132.810.428.200'], ['G01.358.500.249.277'], ['G01.374.661', 'G02.111.490'], ['E05.599.395.642'], ['A08.675', 'A11.671'], ['E05.200.500.905', 'E05.242.800'... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Correlation effects on the dynamics of bipolarons in nondegenerate conjugated polymers. | By employing an adaptive time-dependent density-matrix-renormalization-group method, we investigate the dynamics of a charged bipolaron in the presence of both electron-phonon and electron-electron interactions. We use a Su-Schrieffer-Heeger model modified to include electron-electron interactions via a Hubbard Hamilto... | ['Computer Simulation', 'Electrons', 'Models, Chemical', 'Polymers', 'Time Factors'] | 19,548,757 | [['L01.224.160'], ['G01.249.335', 'G01.358.500.750'], ['E05.599.495'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['G01.910.857']] | ['Information Science [L]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
[Experience gained by treating Alsation dogs]. | In the paper an attempt is made to describe important features in the anatomy and pathology of the Alsation's dentition and how if differs from the human, thus leading to other therapeutic measures. The experience of the author is based upon examination and treatment of 80 institutionalized Alsations bred at the school... | ['Animals', 'Dentition', 'Dog Diseases', 'Dogs', 'Humans', 'Mouth Diseases'] | 2,635,422 | [['B01.050'], ['A03.556.500.379', 'A14.549.167'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.465']] | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cell proliferation index determination by immunohistochemical detection of hCDC47 protein. | A member of the human minichromosome maintenance complex protein family, hCDC47 (alias MCM7) has been identified as a component of the regulatory mechanism in cell proliferation. The expression of this protein, as determined by immunohistochemistry, was investigated to determine its application as a proliferation marke... | ['Animals', 'Antibodies, Monoclonal', 'Biomarkers, Tumor', 'Carcinoma', 'Cell Cycle Proteins', 'Cell Line, Tumor', 'Cell Nucleus', 'Cell Proliferation', 'DNA-Binding Proteins', 'Feasibility Studies', 'Humans', 'Immunohistochemistry', 'Ki-67 Antigen', 'Mice', 'Mice, Nude', 'Minichromosome Maintenance Complex Component 7... | 20,048,674 | [['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.101.140'], ['C04.557.470.200'], ['D12.776.167'], ['A11.251.210.190', 'A11.251.860.180'], ['A11.284.430.106', 'A11.284.430.214.190.875.117'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.776.260'], ['E05.3... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Adolescent fertility and risky environments: a population-level perspective across the lifespan. | Timing of first reproduction is a key life-history variable with important implications for global economic development and health. Life-history theory predicts that human reproductive strategies are shaped by mortality regimes. This study provides the first test of the relationship between population-level adolescent ... | ['Adolescent', 'Age Factors', 'Environment', 'Female', 'Fertility', 'Humans', 'Male', 'Models, Statistical', 'Risk'] | 22,833,268 | [['M01.060.057'], ['N05.715.350.075', 'N06.850.490.250'], ['G16.500.275', 'N06.230'], ['G08.686.210'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['E05.318.740.600.800', 'G17.680.750', 'N05.715.360.750.625.700', 'N06.850.520.830.600... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparison of the effects of chlordiazepoxide and CL 218,872 on serum corticosterone concentrations in rats. | Fifteen minute exposure to a novel environment plus 120 dB sound stimulation produced a three-fold increase in serum corticosterone concentrations in rats. A low dose of intraperitoneally (IP) administered chlordiazepoxide (CDP) (5 mg/kg) attenuated this response, whereas a higher dose (20 mg/kg) elevated corticosteron... | ['Animals', 'Anti-Anxiety Agents', 'Chlordiazepoxide', 'Corticosterone', 'Injections, Intraventricular', 'Male', 'Pyridazines', 'Rats', 'Stress, Psychological'] | 2,884,689 | [['B01.050'], ['D27.505.696.277.950.015', 'D27.505.954.427.210.950.015', 'D27.505.954.427.700.872.015'], ['D03.633.100.079.080.150'], ['D04.210.500.745.745.654.237', 'D06.472.040.585.353.237'], ['E02.319.267.530.550'], ['D03.383.710'], ['B01.050.150.900.649.313.992.635.505.700'], ['F01.145.126.990', 'F02.830.900']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Base excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracil. | 5-Fluorouracil (5-FU), a chemotherapeutic drug commonly used in cancer treatment, imbalances nucleotide pools, thereby favoring misincorporation of uracil and 5-FU into genomic DNA. The processing of these bases by DNA repair activities was proposed to cause DNA-directed cytotoxicity, but the underlying mechanisms have... | ['Animals', 'Antimetabolites, Antineoplastic', 'Cell Cycle', 'Cell Death', 'Cell Line, Tumor', 'DNA Damage', 'DNA Glycosylases', 'DNA Repair', 'Fluorouracil', 'Mice', 'Neoplasms', 'Signal Transduction', 'Thymine DNA Glycosylase', 'Uracil-DNA Glycosidase'] | 19,402,749 | [['B01.050'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['G04.144'], ['G04.146'], ['A11.251.210.190', 'A11.251.860.180'], ['G05.200'], ['D08.811.074.249', 'D08.811.277.450.430.099'], ['G02.111.222', 'G05.219'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.992.635.505.500'], ['C04'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Ecotoxicity of sediments in rivers: Invertebrate community, toxicity bioassays and the toxic unit approach as complementary assessment tools. | The determination of the real toxicity of sediments in aquatic ecosystems is challenging and necessary for an appropriate risk assessment. Different approaches have been developed and applied over the last several decades. Currently, the joint implementation of chemical, ecological and toxicological tools is recommende... | ['Aliivibrio fischeri', 'Animals', 'Biological Assay', 'Chlorophyta', 'Ecosystem', 'Ecotoxicology', 'Environmental Monitoring', 'Geologic Sediments', 'Rivers', 'Water Pollutants, Chemical'] | 26,118,861 | [['B03.440.450.900.050.860', 'B03.660.250.830.050.860'], ['B01.050'], ['E05.091'], ['B01.650.940.150'], ['G16.500.275.157', 'N06.230.124'], ['H01.158.273.248.500', 'H01.158.891.211', 'H01.277.249.500', 'H02.884.211'], ['N06.850.460.350.080', 'N06.850.780.375'], ['G01.311.330', 'G16.500.320'], ['G01.311.750', 'G16.500.2... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Lipid core nanoparticles as a broad strategy to reverse fluconazole resistance in multiple Candida species. | Fungal resistance is the major problem related to fluconazole treatments. This study aims to develop innovative lipid core nanocapsules and nanostructured lipid carriers containing fluconazole, to study in vitro antifungal activity and to assess the possibility of resistance reversion in Candida albicans, C. glabrata, ... | ['ATP-Binding Cassette Transporters', 'Antifungal Agents', 'Candida', 'Candida albicans', 'Candida glabrata', 'Candida tropicalis', 'Caprylates', 'Delayed-Action Preparations', 'Drug Compounding', 'Drug Resistance, Fungal', 'Fluconazole', 'Fungal Proteins', 'Gene Expression', 'Genes, MDR', 'Hexoses', 'Hydrogen-Ion Conc... | 30,579,053 | [['D12.776.157.530.100', 'D12.776.395.550.020', 'D12.776.543.550.192', 'D12.776.543.585.100'], ['D27.505.954.122.136'], ['B01.300.107.795.095', 'B01.300.381.147', 'B01.300.930.176'], ['B01.300.107.795.095.326', 'B01.300.381.147.326', 'B01.300.930.176.326'], ['B01.300.107.795.095.400', 'B01.300.381.147.400', 'B01.300.93... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Onchocerciasis in travelers to the tropics]. | Two men, aged 54 and 31 years respectively, developed an itching skin rash 18 and 6 months respectively after returning from a trip to Africa, the former also recurrent conjunctivitis. Two years and 6 months, respectively, passed from the time of first symptoms until the diagnosis of onchocerciasis was made. Both patie... | ['Adult', 'Animals', 'Antibodies, Helminth', 'Eosinophilia', 'Humans', 'Ivermectin', 'Male', 'Microfilariae', 'Middle Aged', 'Onchocerca', 'Onchocerciasis', 'Onchocerciasis, Ocular', 'Skin', 'Time Factors', 'Travel', 'Tropical Climate'] | 2,401,191 | [['M01.060.116'], ['B01.050'], ['D12.776.124.486.485.114.185', 'D12.776.124.790.651.114.185', 'D12.776.377.715.548.114.185'], ['C15.378.553.231'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.540.576.500.997'], ['B01.050.500.500.294.400.937.463.470', 'B05.525'], ['M01.060.116.630'], ['B01.050.500.500.294.400.... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Mesenteric irritation as a means to prevent internal hernia formation after laparoscopic gastric bypass surgery. | INTRODUCTION: Internal hernias (IHs) occur more frequently in laparoscopic gastric bypass (LGB) surgery than in the classic open procedure. The incidence of small bowel obstruction after LGB ranges from 1.8% and 9.7%. Some have theorized that this occurs because of decreased adhesion formation.METHODS: The mesenteric i... | ['Female', 'Gastric Bypass', 'Hernia, Abdominal', 'Humans', 'Incidence', 'Laparoscopy', 'Male', 'Mesentery', 'Middle Aged', 'Postoperative Complications', 'Retrospective Studies', 'Treatment Outcome'] | 24,791,637 | [['E02.650.500.062.249', 'E04.035.398.385', 'E04.062.249', 'E04.210.457.430'], ['C23.300.707.374'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['E01.370.388.250.520', 'E04.502.250.520'], ['A01.923.047... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Kinetic analysis of 5 alpha-reductase isoenzymes in benign prostatic hyperplasia (BPH). | Kinetic parameters (KM and Vmax) of the 5 alpha-reductase activities in homogenates of stroma and epithelium, isolated from BPH tissue, were determined using both testosterone and progesterone as substrate. The mean KM values for stromal 5 alpha-reductase, at 67.9 nM and 27.7 nM for testosterone and progesterone respec... | ['3-Oxo-5-alpha-Steroid 4-Dehydrogenase', 'Aged', 'Epithelium', 'Humans', 'Isoenzymes', 'Kinetics', 'Male', 'Middle Aged', 'Oxidoreductases', 'Prostate', 'Prostatic Hyperplasia', 'Substrate Specificity'] | 6,193,340 | [['D08.811.682.660.465'], ['M01.060.116.100'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D08.811.348', 'D12.776.800.300'], ['G01.374.661', 'G02.111.490'], ['M01.060.116.630'], ['D08.811.682'], ['A05.360.444.575', 'A10.336.707'], ['C12.294.565.500'], ['G02.111.835']] | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Investigation and surgery in irritable bowel syndrome--a cautionary series. | Irritable bowel syndrome is a common problem, and, with a broad symptom complex, likely to present to a wide variety of clinicians. Lack of awareness of these manifestations may lead to inappropriate investigation, and surgery. Six patients with irritable bowel syndrome who had multiple investigations and operations ar... | ['Adolescent', 'Adult', 'Colonic Diseases, Functional', 'Diagnosis, Differential', 'Humans', 'Middle Aged', 'Prognosis', 'Reoperation', 'Treatment Failure'] | 8,720,770 | [['M01.060.057'], ['M01.060.116'], ['C06.405.469.158.272'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.789'], ['E04.690'], ['E01.789.800.760', 'N04.761.559.590.800.760', 'N05.715.360.575.575.800.760']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prevalence of metabolic syndrome and associated socioeconomic and demographic factors among Palestinian adults (20-65 years) at the Gaza Strip. | OBJECTIVES: Metabolic syndrome (MetS) is a multifaceted syndrome and has been described as a clustering of several risk factors for cardiovascular disease. This study was conducted to estimate the prevalence of MetS and its individual components among Palestinian adults, 20-65 years old in Gaza Strip. In addition to fi... | ['Adult', 'Aged', 'Arabs', 'Cross-Sectional Studies', 'Demography', 'Female', 'Humans', 'Male', 'Marital Status', 'Metabolic Syndrome', 'Middle Aged', 'Middle East', 'Prevalence', 'Socioeconomic Factors', 'Young Adult'] | 22,813,411 | [['M01.060.116'], ['M01.060.116.100'], ['M01.686.754.167'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.263.315.500', 'I01.240.361.500', 'I01.880.853.150.423.500', 'N01.224.361.500', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Influence of phasic muscle contraction upon the quadripulse stimulation (QPS) aftereffects. | OBJECTIVE: Contractions of the target muscle influence the aftereffects of repetitive transcranial magnetic stimulation (rTMS). The aim of this paper is to investigate whether or not voluntary hand movement influences the aftereffects of quadripulse stimulation (QPS) on the hand motor area.METHODS: Thirteen healthy vol... | ['Adult', 'Electromyography', 'Evoked Potentials, Motor', 'Female', 'Hand', 'Humans', 'Male', 'Middle Aged', 'Motor Cortex', 'Movement', 'Muscle Contraction', 'Muscle, Skeletal', 'Transcranial Magnetic Stimulation'] | 26,702,773 | [['M01.060.116'], ['E01.370.405.255', 'E01.370.530.255'], ['G07.265.216.500.385', 'G11.561.200.500.385'], ['A01.378.800.667'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A08.186.211.200.885.287.500.270.548', 'A08.186.211.200.885.287.500.814.624'], ['G07.568', 'G11.427.410'], ['G11.427.494']... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Amelioration of psoriasis by anti-TNF-alpha RNAi in the xenograft transplantation model. | Tumor necrosis factor-alpha (TNF-alpha) is upregulated in psoriatic skin and represents a prominent target in psoriasis treatment. The level of TNF-alpha-encoding mRNA, however, is not increased in psoriatic skin, and it remains unclear whether intervention strategies based on RNA interference (RNAi) are therapeuticall... | ['Animals', 'Cell Line', 'Disease Models, Animal', 'Genetic Vectors', 'Humans', 'Lentivirus', 'Mice', 'Mice, SCID', 'Polymerase Chain Reaction', 'Psoriasis', 'RNA Interference', 'Transplantation, Heterologous', 'Tumor Necrosis Factor-alpha'] | 19,568,223 | [['B01.050'], ['A11.251.210'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G05.360.337'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B04.820.650.589'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.150.900.649.313.992.635.505.500.550.780'], ['E05.393.620.500'], ['C17.800.859.675'], ['G05.308.203.3... | ['Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Monoclonal antibody K1 reacts with epithelial mesothelioma but not with lung adenocarcinoma. | Immunoperoxidase histochemical staining of cryostat sections from human tumor tissues revealed that a murine monoclonal antibody (MAb), K1, can distinguish epithelial mesotheliomas from lung adenocarcinomas. All of 15 epithelial-type mesotheliomas and all four mixed type mesothelioma samples, but none of 23 lung adenoc... | ['Adenocarcinoma', 'Animals', 'Antibodies, Monoclonal', 'Cell Line', 'Diagnosis, Differential', 'Female', 'Fluorescent Antibody Technique', 'Humans', 'Immunoenzyme Techniques', 'Immunologic Tests', 'Lung Neoplasms', 'Male', 'Mesothelioma', 'Mice', 'Pleural Neoplasms'] | 1,599,018 | [['C04.557.470.200.025'], ['B01.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['A11.251.210'], ['E01.171'], ['E01.370.225.500.607.512.240', 'E01.370.225.750.551.512.240', 'E05.200.500.607.512.240', 'E05.200.750.551.512.240', 'E05.478.583.375'], ['B01.050.150.900.6... | ['Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Efficient synthesis of dibenzo[a,c]cyclohepten-5-ones via a sequential Suzuki-Miyaura coupling and aldol condensation reaction. | A common strategy for the synthesis of a 7-membered-ring system with a Suzuki-Miyaura coupling followed by an acid/base-promoted intramolecular aldol condensation reaction has been developed. The reaction of 2'-bromoacetophenones with 2-formylphenylboronic acids in the presence of Pd(OAc)(2) and CataCXium PIntB L8 effi... | ['Aldehydes', 'Catalysis', 'Cycloheptanes', 'Ligands'] | 19,354,227 | [['D02.047'], ['G02.130'], ['D02.455.426.392.368.284'], ['D27.720.470.480']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Effect of amphipathic helix characteristics of FtsZ (236-245) domain on FtsZ assembly and its function in Escherichia coli strains]. | Objective: To study the effect of amphipathic helix characteristics of FtsZ (236-245) domain on FtsZ assembly and interaction of FtsZ with FtsA in Escherichia coli strains.Methods: We constructed FtsZ and its mutant's plasmids by molecular clone and site-directed mutagenesis, and purified targeted proteins using affini... | ['Amino Acid Motifs', 'Bacterial Proteins', 'Cytoskeletal Proteins', 'Escherichia coli', 'Escherichia coli Proteins', 'Mutagenesis, Site-Directed', 'Mutation', 'Protein Binding', 'Protein Domains'] | 29,756,735 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['D12.776.097'], ['D12.776.220'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.097.275'], ['E05.393.420.601.575'], ['G05.365.590'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709.275.750', 'G02.111.570.820.709.610.500']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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