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A full assignment of proton resonances for an alpha(1-3)-linked fucose residue in keratan sulphate from bovine articular cartilage.
Full proton NMR assignments have been achieved for the alpha(1-3)-linked fucose residues contained in alkaline borohydride reduced keratan sulphate chains derived from bovine articular cartilage. This involved 500 MHz spectroscopy at 60 degrees C and included COSY and RELAYED-COSY determinations.
['Animals', 'Carbohydrate Conformation', 'Carbohydrate Sequence', 'Cartilage, Articular', 'Cattle', 'Fucose', 'Keratan Sulfate', 'Magnetic Resonance Spectroscopy', 'Molecular Sequence Data', 'Protons']
1,668,530
[['B01.050'], ['G02.111.570.820.235'], ['G02.111.570.160', 'L01.453.245.667.160'], ['A02.165.407.150', 'A02.835.583.192'], ['B01.050.150.900.649.313.500.380.271'], ['D09.254.488'], ['D09.698.373.550'], ['E05.196.867.519'], ['L01.453.245.667'], ['D01.248.497.300.459.700', 'D01.268.406.750', 'D01.362.340.750', 'G01.249.6...
['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
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Endothelial nitric oxide synthase modulates gastric ulcer healing in rats.
Nitric oxide has been shown to be beneficial for gastric ulcer healing. We determined the relative effects of endothelial and inducible nitric oxide synthases on gastric ulcer healing in rats. Ulcers were induced by serosal application of acetic acid. Ulcer severity, angiogenesis, and nitric oxide synthase expression w...
['Animals', 'Endothelium, Vascular', 'Enzyme Inhibitors', 'Gene Expression Regulation, Enzymologic', 'Lysine', 'Male', 'NG-Nitroarginine Methyl Ester', 'Neovascularization, Physiologic', 'Nitric Oxide Synthase', 'Nitric Oxide Synthase Type II', 'Nitric Oxide Synthase Type III', 'RNA, Messenger', 'Rats', 'Rats, Wistar',...
10,915,643
[['B01.050'], ['A07.015.700.500', 'A10.272.491.355'], ['D27.505.519.389'], ['G05.308.320'], ['D12.125.068.555', 'D12.125.095.647', 'D12.125.142.497'], ['D12.125.068.050.525', 'D12.125.095.104.525'], ['G09.330.630'], ['D08.811.682.664.500.772'], ['D08.811.682.664.500.772.500', 'D12.776.157.687.575', 'D12.776.660.720.575...
['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]']
1
1
1
1
0
0
1
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0
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Volunteer kinematics and reaction in lateral emergency maneuver tests.
It is important to understand human kinematics and muscle activation patterns in emergency maneuvers for the design of safety systems and for the further development of human models. The objective of this study was to quantify kinematic behavior and muscle activation in simulated steering tests in several realistic con...
['Accidents, Traffic', 'Adult', 'Automobile Driving', 'Biomechanical Phenomena', 'Electromyography', 'Head', 'Humans', 'Male', 'Middle Aged', 'Muscle, Skeletal', 'Neck Muscles']
24,435,737
[['N06.850.135.392'], ['M01.060.116'], ['I03.125'], ['G01.154.090', 'G01.374.089'], ['E01.370.405.255', 'E01.370.530.255'], ['A01.456'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A02.633.567', 'A10.690.552.500'], ['A02.633.567.650']]
['Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]']
1
1
0
0
1
0
1
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1
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Effects of methyl methanesulfonate on mouse sperm chromatin structure and testicular cell kinetics.
Effects of methyl methanesulfonate (MMS) on mouse testicular cell kinetics and sperm chromatin structure were determined flow cytometrically. Mice were exposed to a single ip injection of saline containing 0 or 150 mg/kg MMS. Relative ratios of 1N, 2N and 4N testicular cells were not affected until 22 days postexposure...
['Alkylation', 'Animals', 'Chromatin', 'DNA', 'Flow Cytometry', 'Male', 'Methyl Methanesulfonate', 'Mice', 'Mice, Inbred C3H', 'Mice, Inbred C57BL', 'Pilot Projects', 'Ploidies', 'Random Allocation', 'Sperm Head', 'Spermatozoa', 'Testis']
8,444,143
[['G02.111.035', 'G02.607.094', 'G03.059'], ['B01.050'], ['A11.284.430.106.279.345.190.160.180', 'D12.776.664.224', 'G05.360.160.180'], ['D13.444.308'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350...
['Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
1
1
0
1
1
0
1
0
0
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1
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Embryo recovery from exercised mares.
The effect of exercise on mare reproductive efficiency was evaluated by comparing rates of embryo recovery from mares assigned to either an exercise regimen or a non-exercise (control) regimen. Exercised mares were worked daily for 30 min under average ambient conditions of >30 degrees C and >50% humidity. Mares were i...
['Animals', 'Body Temperature', 'Embryo Transfer', 'Female', 'Horses', 'Insemination, Artificial', 'Male', 'Ovulation Induction', 'Physical Conditioning, Animal', 'Pregnancy', 'Random Allocation']
18,295,989
[['B01.050'], ['E01.370.600.875.374', 'G07.110'], ['E02.875.800.500', 'E05.820.800.500'], ['B01.050.150.900.649.313.984.235.472'], ['E02.875.800.937', 'E05.820.800.937', 'G08.686.784.363.492'], ['E02.875.800.984', 'E05.820.800.984'], ['G11.427.410.698.277.280'], ['G08.686.784.769'], ['E05.318.370.700', 'E05.581.500.805...
['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]']
0
1
0
0
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Clinicopathological and biological assessment of lung cancers with pleural dissemination.
BACKGROUND: This study provides the surgical outcome of lung cancer patients with pleural dissemination, with the assessment of the clinicopathological and biological prognostic factors.METHODS: Forty-three patients who underwent operations were studied. Vascular endothelial growth factor (VEGF) and autocrine motility ...
['Adenocarcinoma', 'Adult', 'Aged', 'Carcinoma, Squamous Cell', 'Endothelial Growth Factors', 'Female', 'Glucose-6-Phosphate Isomerase', 'Humans', 'Immunohistochemistry', 'Lung Neoplasms', 'Lymphokines', 'Male', 'Middle Aged', 'Pleura', 'Prognosis', 'Vascular Endothelial Growth Factor A', 'Vascular Endothelial Growth F...
10,800,788
[['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['D12.644.276.390', 'D12.776.467.390', 'D23.529.390'], ['D08.811.399.475.200.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512...
['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]']
1
1
1
1
1
0
0
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Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority trial.
BACKGROUND: For children with sickle cell anaemia and high transcranial doppler (TCD) flow velocities, regular blood transfusions can effectively prevent primary stroke, but must be continued indefinitely. The efficacy of hydroxycarbamide (hydroxyurea) in this setting is unknown; we performed the TWiTCH trial to compar...
['Adolescent', 'Anemia, Sickle Cell', 'Antisickling Agents', 'Blood Flow Velocity', 'Blood Transfusion', 'Cerebrovascular Circulation', 'Child', 'Child, Preschool', 'Combined Modality Therapy', 'Drug Substitution', 'Female', 'Humans', 'Hydroxyurea', 'Male', 'Stroke', 'Treatment Outcome', 'Ultrasonography, Doppler, Tran...
26,670,617
[['M01.060.057'], ['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['D27.505.954.502.135'], ['E01.370.370.130', 'G09.330.380.630.080'], ['E02.095.135'], ['G09.330.100.159'], ['M01.060.406'], ['M01.060.406.448'], ['E02.186'], ['E02.319.307.312', 'N02.421.668.778.500.312'], ['B01.050....
['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]']
0
1
1
1
1
0
1
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0
0
0
1
1
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E3 ubiquitin ligase HOIP attenuates apoptotic cell death induced by cisplatin.
The genotoxin cisplatin is commonly used in chemotherapy to treat solid tumors, yet our understanding of the mechanism underlying the drug response is limited. In a focused siRNA screen, using an siRNA library targeting genes involved in ubiquitin and ubiquitin-like signaling, we identified the E3 ubiquitin ligase HOIP...
['Antineoplastic Agents', 'Apoptosis', 'Cell Cycle Checkpoints', 'Cell Death', 'Cisplatin', 'DNA Damage', 'Female', 'HCT116 Cells', 'HEK293 Cells', 'HeLa Cells', 'Humans', 'MAP Kinase Kinase 4', 'Ovarian Neoplasms', 'RNA, Small Interfering', 'Signal Transduction', 'Ubiquitin-Protein Ligases']
24,686,174
[['D27.505.954.248'], ['G04.146.954.035'], ['G04.144.109'], ['G04.146'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['G05.200'], ['A11.251.210.190.380', 'A11.251.860.180.380'], ['A11.251.210.172.750', 'A11.436.334'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.11...
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]']
1
1
1
1
0
0
1
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A phase II trial comparing five dose levels of BEC2 anti-idiotypic monoclonal antibody vaccine that mimics GD3 ganglioside.
In previous studies, we showed that immunization with 2.5 mg of BEC2, an anti-idiotypic MAb that mimics GD3 ganglioside, can induce antibodies against GD3 in approximately 25% of patients. In this trial, 50 melanoma patients at high risk for recurrence were randomly assigned to one of the five BEC2 dose levels (2.5 mic...
['Adjuvants, Immunologic', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Antibodies, Monoclonal', 'BCG Vaccine', 'Cancer Vaccines', 'Chemistry, Pharmaceutical', 'Child', 'Child, Preschool', 'Dose-Response Relationship, Immunologic', 'Ether-A-Go-Go Potassium Channels', 'Female', 'Gangliosides', 'Humans', 'Immuniz...
15,246,627
[['D27.505.696.477.067'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D20.215.894.135.825.100'], ['D20.215.894.200'], ['H01.158.703.007', 'H01.181.466'], ['M01.060.406'], ['M01.060.406.44...
['Chemicals and Drugs [D]', 'Named Groups [M]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]']
0
1
1
1
1
0
1
1
0
0
0
1
1
0
Epithelial-mesenchymal transition induced by GRO-á-CXCR2 promotes bladder cancer recurrence after intravesical chemotherapy.
Non-muscle invasive bladder cancers (NMIBC) are typically treated by transurethral resection with intravesical chemotherapy. However, the post-therapeutic incidence of tumor recurrence and progression to muscle invasive disease is high, and the underlying mechanism(s) remains unknown. In this study, we observed that re...
['Administration, Intravesical', 'Animals', 'Chemokine CXCL1', 'Epirubicin', 'Epithelial-Mesenchymal Transition', 'Female', 'HEK293 Cells', 'Humans', 'Mice', 'Mice, Inbred BALB C', 'Mice, Nude', 'Neoplasm Recurrence, Local', 'Random Allocation', 'Receptors, Interleukin-8B', 'Urinary Bladder Neoplasms', 'Xenograft Model...
28,423,359
[['E02.319.267.120.505'], ['B01.050'], ['D12.644.276.374.200.120.050', 'D12.776.467.374.200.120.050', 'D12.776.624.664.700.049', 'D23.125.300.120.050', 'D23.469.200.120.050', 'D23.529.374.200.120.050'], ['D02.455.426.559.847.562.050.200.175.200', 'D04.615.562.050.200.175.200', 'D09.408.051.059.200.175.200'], ['G04.356....
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]']
1
1
1
1
1
0
1
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0
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1
0
Magnetic source imaging versus intracranial electroencephalogram in epilepsy surgery: a prospective study.
OBJECTIVE: Noninvasive brain imaging tests can potentially supplement or even replace the use of intracranial electroencephalogram (ICEEG), an invasive, costly procedure used in presurgical epilepsy evaluation. This study prospectively examined the agreement between magnetic source imaging (MSI) and ICEEG localization ...
['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Electroencephalography', 'Epilepsy', 'Female', 'Humans', 'Infant', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Neurosurgical Procedures', 'Predictive Value of Tests', 'Prospective Studies', 'Surgery, Computer-Assisted']
16,634,031
[['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['E01.370.376.300', 'E01.370.405.245'], ['C10.228.140.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['E04.525'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.5...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]']
0
1
1
0
1
0
0
0
0
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0
1
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Oxygen uptake activity and aerobic metabolism of Streptococcus thermophilus STH450.
Streptococcus thermophilus STH450 had a very high oxygen uptake. This strain was then compared with aerobic metabolism to S. thermophilus ATCC 19258, a reference strain for aerobic metabolism. Molecular oxygen, which was absorbed by S. thermophilus STH450 during aerobic glycolytic metabolism, was involved in the oxidat...
['Animals', 'Cattle', 'In Vitro Techniques', 'Milk', 'Oxygen Consumption', 'Streptococcus']
3,584,599
[['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['E05.481'], ['A12.200.455', 'A12.790', 'G07.203.100.700', 'G07.203.300.350.525', 'J02.200.700', 'J02.500.350.525'], ['G03.680'], ['B03.353.750.737.872', 'B03.510.400.800.872', 'B03.510.550.737.872']]
['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]']
1
1
0
0
1
0
1
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0
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0
0
0
[Clinical experiences of breast reconstruction using deep inferior epigastric perforator flaps].
OBJECTIVE: To summarize the experiences of the breast reconstruction using the deep inferior epigastric perforator (DIEP) flaps.METHODS: From March 2000 to March 2005, 18 cases of breast defects were treated. Defect was caused by mammary cancer in 17 cases and by Poland's syndrome in 1 case. Preoperative radiotherapy w...
['Adult', 'Breast Neoplasms', 'Epigastric Arteries', 'Female', 'Humans', 'Mammaplasty', 'Middle Aged', 'Skin Transplantation', 'Surgical Flaps']
16,752,842
[['M01.060.116'], ['C04.588.180', 'C17.800.090.500'], ['A07.015.114.330'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.218.565', 'E04.680.500'], ['M01.060.116.630'], ['E02.095.147.725.700', 'E04.680.275.850', 'E04.936.580.700'], ['A10.850.710', 'E07.862.710']]
['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
1
0
1
0
0
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Highly efficient Fenton and enzyme-mimetic activities of NH2
Here, we show that NH2-MIL-88B(Fe) can be used as a peroxidase-like catalyst for Fenton-like degradation of methylene blue (MB) in water. The iron-based NH2-MIL-88B(Fe) metal organic framework (MOF) was synthesized by a facile and rapid microwave heating method. It was characterized by scanning electron microscopy, Fou...
['Adsorption', 'Catalysis', 'Coloring Agents', 'Electron Spin Resonance Spectroscopy', 'Hydrogen Peroxide', 'Hydrogen-Ion Concentration', 'Hydroxyl Radical', 'Iron', 'Lysergic Acid Diethylamide', 'Metal-Organic Frameworks', 'Methylene Blue', 'Microscopy, Electron, Scanning', 'Oxidation-Reduction', 'Spectroscopy, Fourie...
29,581,533
[['G01.030', 'G02.020'], ['G02.130'], ['D27.720.233'], ['E05.196.867.519.274'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['G02.300'], ['D01.045.250.357', 'D01.248.497.158.459.300', 'D01.339.431.249'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['D...
['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
0
0
0
1
1
0
1
0
0
0
0
0
1
0
Giant adrenal myelolipoma associated with 21-hydroxylase deficiency: unusual association mimicking an androgen-secreting adrenocortical carcinoma.
The objective of this study was to describe a case of giant myelolipoma associated with undiagnosed congenital adrenal hyperplasia (CAH) due to 21-hydroxylase (21OH) deficiency. Five seven year-old male patient referred with abdominal ultrasound revealing a left adrenal mass. Biochemical investigation revealed hyperand...
['Adrenal Cortex Neoplasms', 'Adrenal Hyperplasia, Congenital', 'Adrenocortical Carcinoma', 'Diagnosis, Differential', 'Humans', 'Male', 'Middle Aged', 'Myelolipoma', 'Steroid 21-Hydroxylase']
20,625,655
[['C04.588.322.078.265', 'C19.053.098.265', 'C19.053.347.500', 'C19.344.078.265'], ['C12.706.316.090.500', 'C13.351.875.253.090.500', 'C16.131.939.316.129.500', 'C16.320.033', 'C16.320.565.925.249', 'C18.452.648.925.249', 'C19.053.440', 'C19.391.119.090.500'], ['C04.557.470.200.025.152', 'C04.588.322.078.265.750', 'C19...
['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]']
0
1
1
1
1
0
0
0
0
0
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1
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Nanocomposite edible films from mango puree reinforced with cellulose nanofibers.
Cellulose nanoreinforcements have been used to improve mechanical and barrier properties of biopolymers, whose performance is usually poor when compared to those of synthetic polymers. Nanocomposite edible films have been developed by adding cellulose nanofibers (CNF) in different concentrations (up to 36 g/100 g) as n...
['Calorimetry, Differential Scanning', 'Cellulose', 'Elastic Modulus', 'Food Packaging', 'Mangifera', 'Materials Testing', 'Mechanical Phenomena', 'Microscopy, Electron, Scanning', 'Microscopy, Electron, Transmission', 'Nanocomposites', 'Nanotechnology', 'Permeability', 'Surface Properties', 'Tensile Strength', 'Transi...
19,646,052
[['E05.196.131.310', 'E05.196.370.310'], ['D05.750.078.562.180', 'D09.698.365.180', 'D25.720.099.500', 'J01.637.051.720.099.500'], ['G01.374.590.605'], ['J01.576.423.200.375', 'J01.576.423.850.600', 'J01.576.761.400'], ['B01.650.940.800.575.912.250.044.416'], ['E05.570'], ['G01.374'], ['E01.370.350.515.402.541', 'E05.5...
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Disciplines and Occupations [H]']
0
1
0
1
1
0
1
1
0
1
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0
0
0
Gut Dysbiosis in Patients with Anorexia Nervosa.
Anorexia nervosa (AN) is a psychological illness with devastating physical consequences; however, its pathophysiological mechanism remains unclear. Because numerous reports have indicated the importance of gut microbiota in the regulation of weight gain, it is reasonable to speculate that AN patients might have a micro...
['Adult', 'Anorexia Nervosa', 'Case-Control Studies', 'Dysbiosis', 'Feces', 'Female', 'Gastrointestinal Microbiome', 'Humans', 'Young Adult']
26,682,545
[['M01.060.116'], ['F03.400.125'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['C23.550.308'], ['A12.459'], ['G06.591.375', 'G16.500.275.157.049.100.500.375', 'N06.230.124.049.100.500.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.815']]
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]']
1
1
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0
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Multiple conformations of 5-HT2A and 5-HT 2C receptors in rat brain: an autoradiographic study with [125I](±)DOI.
Earlier autoradiographic studies with the 5-HT2 receptor agonist [(125)I](±)DOI in human brain showed unexpected biphasic competition curves for various 5-HT2A antagonists. We have performed similar studies in rat brain regions with selective 5-HT2A (M100907) and 5-HT2C (SB242084) antagonists together with ketanserin a...
['Aminopyridines', 'Animals', 'Autoradiography', 'Brain', 'Ergolines', 'Indoles', 'Ketanserin', 'Male', 'Rats', 'Rats, Wistar', 'Receptor, Serotonin, 5-HT2A', 'Receptor, Serotonin, 5-HT2C', 'Serotonin']
23,864,045
[['D02.092.080', 'D03.383.725.050'], ['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['A08.186.211'], ['D03.132.327.287', 'D03.633.400.439'], ['D03.633.100.473'], ['D03.383.621.365', 'D03.633.100.786.830.333'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.70...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]']
1
1
0
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0
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0
0
The nursing workforce: a comparison of three national surveys.
The termination of the National Sample Survey of Registered Nurses (NSSRN) represents a loss of a key source of information on the nursing workforce that has been available for more than 30 years. At the same time, this loss presents new opportunities to address some of the biases associated with using licensing data t...
['Adult', 'Censuses', 'Female', 'Health Care Surveys', 'Humans', 'Licensure, Nursing', 'Male', 'Middle Aged', 'Nursing', 'Research Design', 'Selection Bias', 'United States', 'United States Health Resources and Services Administration', 'Workforce']
23,198,607
[['M01.060.116'], ['I01.240.205', 'N01.224.175', 'N06.850.505.400.225'], ['E05.318.308.980.344', 'N03.349.380.210', 'N05.425.210', 'N05.715.360.300.800.344', 'N06.850.520.308.980.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.706.110.510.490', 'N05.700.200.450.550'], ['M01.060.116.630'], ['H02.478', 'N04...
['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Geographicals [Z]']
0
1
0
0
1
0
0
1
1
0
0
1
1
1
Development and validation of a mathematical equation to estimate glomerular filtration rate in cirrhosis: The royal free hospital cirrhosis glomerular filtration rate.
Current expressions based on serum creatinine concentration overestimate kidney function in cirrhosis, leading to significant differences between "true" and calculated glomerular filtration rate (GFR). We compared the performance of the four-variable and six-variable Modification of Diet in Renal Disease and chronic ki...
['Adult', 'Aged', 'Cohort Studies', 'Creatinine', 'Female', 'Glomerular Filtration Rate', 'Greece', 'Humans', 'Liver Cirrhosis', 'Liver Transplantation', 'Male', 'Middle Aged', 'Models, Theoretical', 'Multivariate Analysis', 'Preoperative Care', 'Regression Analysis', 'Renal Insufficiency, Chronic', 'Retrospective Stud...
27,779,785
[['M01.060.116'], ['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['D03.383.129.308.207'], ['E01.370.390.400.300', 'G08.852.357'], ['Z01.542.383'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.552.630', 'C23.550.355.412'], ['E02.095.147.725.490', 'E04.210.65...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]']
0
1
1
1
1
0
1
0
0
0
0
1
1
1
Leptin concentrations in maternal serum and amniotic fluid during the second trimenon: differential relation to fetal gender and maternal morphometry.
Leptin, a hormone produced by adipocytes, provides information on the availability of fat stores to the hypothalamus and acts as an afferent satiety signal regulating appetite and energy expenditure in both rodents and humans [Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mou...
['Adult', 'Amniotic Fluid', 'Body Mass Index', 'Chorionic Gonadotropin', 'Estriol', 'Female', 'Fetus', 'Humans', 'Leptin', 'Male', 'Middle Aged', 'Pregnancy', 'Pregnancy Trimester, Second', 'Sex Factors', 'Skinfold Thickness', 'Time Factors', 'alpha-Fetoproteins']
10,509,783
[['M01.060.116'], ['A12.098', 'A16.378.149'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['D04.210.500.365.415.331', 'D06.472.334.851.437.750'], ['A16.378'], ['B01.050.150.900.649...
['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]']
1
1
0
1
1
0
1
0
0
0
0
1
1
0
[Clinicoimmunological values of measurement of IgG-Fc receptor positive T cells in the patients with malignant brain tumors].
It has recently been shown that human T-cell subpopulation can be identified functionally via surface receptors for Fc fragment of immunoglobulins. We detected peripheral blood T-cells bearing the Fc receptor for IgG molecules (T gamma cell) in patients with brain tumors who manifested a variety of immunological abnorm...
['Antibody-Dependent Cell Cytotoxicity', 'Brain Neoplasms', 'Glioma', 'Humans', 'Immunoglobulin Fc Fragments', 'Lymphocyte Activation', 'Receptors, IgG', 'Receptors, Immunologic', 'T-Lymphocytes']
2,934,080
[['G12.287.070'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.541.500.697', 'D12.776.124.486.485.538.500', 'D12.776.124.486.485.680.697', 'D12.776.124.790.651.538....
['Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]']
1
1
1
1
1
0
1
0
0
0
0
0
0
0
[Screening for undernutrition among older adults receiving home care: an estimation of the diagnostic accuracy of indicators available in the Resident Assessment Instrument - Home Care adapted for Switzerland.]
INTRODUCTION: in homecare practice, nurses are central actors for the screening of individuals at risks of undernutrition.CONTEXT: in Switzerland, homecare nurses estimate the nutritional status of care recipients by means of a standardized geriatric assessment done with the RAI-HC.AIMS: The aim of the study is to esti...
['Aged', 'Geriatric Assessment', 'Home Care Services', 'Humans', 'Malnutrition', 'Mass Screening', 'Nutrition Assessment', 'Reproducibility of Results', 'Switzerland']
29,771,099
[['M01.060.116.100'], ['E05.318.308.225', 'I01.240.425.350', 'N01.224.425.350', 'N05.715.360.300.360', 'N06.850.505.400.425.350', 'N06.850.520.308.225'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.654.521'], ['E01.370.500', 'E05.318.308.980.438.580', 'N02.421.726.233....
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]']
0
1
1
0
1
0
0
0
1
0
0
1
1
1
Effect of systemically administered nitric oxide donor, sodium nitroprusside on picrotoxin-induced convulsions in rats.
Nitric oxide (NO), the gaseous neurotransmitter has been reported to have an endogenous anticonvulsant property. This has prompted proposals to develop NO donors as anticonvulsant drugs. In the present study, the effect of NO donor, sodium nitroprusside (SNP) on picrotoxin (PCT)-induced convulsions was investigated. A ...
['Animals', 'Convulsants', 'Dose-Response Relationship, Drug', 'Male', 'Nitric Oxide', 'Nitric Oxide Donors', 'Nitroprusside', 'Picrotoxin', 'Rats', 'Rats, Wistar', 'Seizures', 'Vasodilator Agents']
11,211,577
[['B01.050'], ['D27.505.696.282.224', 'D27.505.954.427.220.224'], ['G07.690.773.875', 'G07.690.936.500'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['D27.505.519.656', 'D27.505.954.411.590'], ['D01.248.497.158.291.350.550', 'D01.490.100.300.550', 'D01.625.400.100.325.550'], ['D02.455...
['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]']
0
1
1
1
0
0
1
0
0
0
0
0
0
0
Oxidative Damage and Nrf2 Translocation Induced by Toxicities of Deoxynivalenol on the Placental and Embryo on Gestation Day 12.5 d and 18.5 d.
Deoxynivalenol (DON) is a kind of natural pollutant belonging to the trichothecenes family. The aim of this study is to use diverse assays to evaluate oxidative damage as well as translocation of nuclear factor erythroid 2-related factor 2 (Nrf2), and to investigate their mechanisms in DON-induced toxicities on a place...
['Animals', 'Embryo, Mammalian', 'Female', 'Glutathione', 'Heme Oxygenase-1', 'Male', 'Malondialdehyde', 'Membrane Proteins', 'Mice, Inbred C57BL', 'NF-E2-Related Factor 2', 'Oxidative Stress', 'Placenta', 'Pregnancy', 'Superoxide Dismutase', 'Trichothecenes']
30,216,983
[['B01.050'], ['A16.254'], ['D12.644.456.448'], ['D08.811.682.690.708.410.500'], ['D02.047.700'], ['D12.776.543'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['D12.776.260.108.737', 'D12.776.930.127.737'], ['G03.673', 'G07.775.750'], ['A16.710'], ['G08.686.784.769'], ['D08.811.6...
['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]']
1
1
0
1
0
0
1
0
0
0
0
0
0
0
Global-to-local policy transfer in the introduction of new molecular tuberculosis diagnostics in South Africa.
SETTING: Lack of innovation in diagnostics has contributed to tuberculosis (TB) remaining a global health challenge. It is critical to understand how new diagnostic technologies are translated into policies and how these are implemented.OBJECTIVE: To examine policy transfer for two rapid molecular diagnostic tests, Gen...
['Humans', 'Longitudinal Studies', 'Molecular Diagnostic Techniques', 'Policy Making', 'South Africa', 'Technology Transfer', 'Tuberculosis']
26,467,585
[['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750.500'], ['E01.370.225.880', 'E05.200.880', 'E05.393.520'], ['N03.706.742'], ['Z01.058.290.175.735'], ['J01.897.900', 'L01.143.320.800'], ['C01.150.252.410.040.552.846']]
['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Diseases [C]']
0
1
1
0
1
0
0
0
0
1
1
0
1
1
The glutathione-binding site in glutathione S-transferases. Investigation of the cysteinyl, glycyl and gamma-glutamyl domains.
The GSH-binding site of glutathione S-transferase (GST) isoenzymes was studied by investigating their substrate-specificity for three series of GSH analogues; further, a model of the interactions of GSH with the G-site is proposed. Twelve glycyl-modified GSH analogues, four ester derivatives of GSH and three cysteinyl-...
['Amino Acid Sequence', 'Animals', 'Binding Sites', 'Chemical Phenomena', 'Chemistry', 'Cysteine', 'Dinitrochlorobenzene', 'Glutamine', 'Glutathione', 'Glutathione Transferase', 'Glycine', 'Isoenzymes', 'Kinetics', 'Liver', 'Molecular Sequence Data', 'Rats', 'Structure-Activity Relationship', 'Substrate Specificity']
2,375,757
[['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.120'], ['G02'], ['H01.181'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['D02.455.426.559.389.261.250', 'D02.455.426.559.389.565.250', 'D02.455.526.439.202.200', 'D02.640.529.240.250', 'D23.050.550.480.350'], ['D1...
['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Anatomy [A]']
1
1
0
1
0
0
1
1
0
0
1
0
0
0
Reliance on God's help, depression and fatigue in female cancer patients.
OBJECTIVE: Because an increasing number of studies indicate that a religious attitude is associated with lower depression, we intended to investigate the interrelationship between intrinsic religiosity and depressive behavioral symptoms in cancer patients with long-term courses.METHOD: In 396 female cancer patients rec...
['Adaptation, Psychological', 'Adult', 'Age Factors', 'Aged', 'Depressive Disorder', 'Existentialism', 'Fatigue', 'Female', 'Germany, East', 'Health Status', 'Humans', 'Mental Fatigue', 'Middle Aged', 'Neoplasms', 'Personal Satisfaction', 'Prevalence', 'Psychiatric Status Rating Scales', 'Quality of Life', 'Religion an...
19,069,578
[['F01.058'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['F03.600.300'], ['F02.739.418', 'K01.752.304'], ['C23.888.369'], ['Z01.586.338'], ['I01.240.425', 'N01.224.425', 'N06.850.505.400.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.888.369.500', 'F01.145.126.937'], [...
['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Humanities [K]', 'Diseases [C]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
1
0
1
1
0
0
1
0
0
1
1
1
Impact of a multidisciplinary vulvodynia program on sexual functioning and dyspareunia.
INTRODUCTION: For many years, multidisciplinary approaches, which integrate psychological, physical, and medical treatments, have been shown to be effective for the treatment of chronic pain. To date, there has been anecdotal support, but little empirical data, to justify the application of this multidisciplinary appro...
['Adult', 'Cognitive Behavioral Therapy', 'Combined Modality Therapy', 'Dyspareunia', 'Emotions', 'Female', 'Follow-Up Studies', 'Humans', 'Libido', 'Pelvic Floor', 'Personal Satisfaction', 'Physical Therapy Modalities', 'Program Evaluation', 'Referral and Consultation', 'Sex Education', 'Sexual Partners', 'Surveys and...
25,354,520
[['M01.060.116'], ['F04.754.137.350'], ['E02.186'], ['C12.294.644.242', 'C13.351.500.665.313', 'F03.835.199'], ['F01.470'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.739.794.511'], ['A01.923.600.600', 'A02.633.567.05...
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]']
1
1
1
0
1
1
0
0
1
0
0
1
1
0
Romanian adolescents' knowledge and attitudes towards human papillomavirus infection and prophylactic vaccination.
OBJECTIVES: Since licensure of HPV vaccine in 2006, HPV vaccine coverage among Romanian adolescents remains worryingly low. The objectives of the study were to assess the knowledge and attitudes towards HPV infection and vaccination among Romanian adolescents and to explore the barriers to HPV vaccination with a view t...
['Adolescent', 'Early Detection of Cancer', 'Female', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Income', 'Logistic Models', 'Male', 'Multivariate Analysis', 'Odds Ratio', 'Papanicolaou Test', 'Papillomavirus Infections', 'Papillomavirus Vaccines', 'Romania', 'Sexual Behavior', 'Surveys and Questionnaires', 'U...
26,479,435
[['M01.060.057'], ['E01.390.500'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.824.417'], ['E05.318.740.500.525', 'E05.318.740.600.800.450', 'E05.318.740.750.450', 'E05.599.835.875', 'N05.715.360.750.530.480', 'N05.715.360.750.625.700.450', 'N05.715.360.750.695.470', '...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Geographicals [Z]']
0
1
1
1
1
1
1
0
0
0
0
1
1
1
Cerebral Lipiodol Embolism after Lymphatic Embolization for Plastic Bronchitis.
An adolescent with plastic bronchitis due to congenital heart disease had altered mental status after an interventional lymphatic procedure in which lipiodol contrast was used. Neuroimaging revealed cerebral lipiodol embolization due to direct shunting between lymphatic channels and pulmonary veins. Cerebral lipiodol e...
['Adolescent', 'Bronchitis', 'Contrast Media', 'Embolization, Therapeutic', 'Ethiodized Oil', 'Humans', 'Intracranial Embolism', 'Lymphatic Vessels', 'Male']
27,297,208
[['M01.060.057'], ['C01.748.099', 'C08.127.446', 'C08.381.495.146', 'C08.730.099'], ['D27.505.259.500', 'D27.720.259'], ['E02.520.360', 'E02.926.500'], ['D10.627.700.550.300', 'D20.215.784.750.550.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.300.525.400', 'C14.907.253.566.300', 'C14.907.355.590...
['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]']
1
1
1
1
1
0
0
0
0
0
0
1
0
0
Renal angiomyolipoma: selective arterial embolization--effectiveness and changes in angiomyogenic components in long-term follow-up.
PURPOSE: To evaluate the efficacy of selective arterial embolization in symptomatic renal angiomyolipoma (AML) and the change in angiomyogenic components during long-term follow-up after embolization.MATERIALS AND METHODS: Fourteen adult patients with symptomatic AMLs underwent 16 selective arterial embolizations. The ...
['Adult', 'Aged', 'Angiomyolipoma', 'Embolization, Therapeutic', 'Female', 'Follow-Up Studies', 'Gelatin Sponge, Absorbable', 'Hemostatics', 'Humans', 'Iodized Oil', 'Kidney Neoplasms', 'Male', 'Middle Aged', 'Polyvinyls', 'Tomography, X-Ray Computed', 'Treatment Outcome']
9,205,224
[['M01.060.116'], ['M01.060.116.100'], ['C04.557.450.550.125', 'C04.557.450.692.249'], ['E02.520.360', 'E02.926.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E07.858.740.300'], ['D27.505.954.502.270.463'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D10.627.7...
['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]']
0
1
1
1
1
0
0
0
0
1
0
1
1
0
Thioredoxin redox status assessment during embryonic development: the redox Western.
Oxidative stress can contribute significantly to the mechanisms that cause teratogenesis and embryotoxicity, but cellular antioxidant defense systems have evolved to counteract the detrimental consequences of oxidative insult. Numerous antioxidant systems exist in developing organisms but have been shown to be dynamica...
['Algorithms', 'Animals', 'Blotting, Western', 'Electrophoresis, Polyacrylamide Gel', 'Embryo, Mammalian', 'Embryonic Development', 'Female', 'Indicators and Reagents', 'Maleimides', 'Mice', 'Mitochondrial Proteins', 'Oxidation-Reduction', 'Oxidative Stress', 'Pregnancy', 'Staining and Labeling', 'Thioredoxins']
22,669,673
[['G17.035', 'L01.224.050'], ['B01.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.196.401.402', 'E05.301.300.319'], ['A16.254'], ['G07.345.500.325.180', 'G08.686.784.170.104'], ['D27.720.470.410'], ['D02.241.081.337.502.524', 'D02.478.440', 'D03.383.129...
['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]']
1
1
0
1
1
0
1
0
0
0
1
0
0
0
Economic impact of terminal illness and the willingness to change it.
OBJECTIVE: To gather pilot data on the economic impact of terminal illness on families and on the feasibility of training caregivers as a method of stemming illness-related poverty.DESIGN: Exploratory, descriptive study involving semistructured interviews with patient and caregiver dyads.SETTING: Pallium India Palliati...
['Absenteeism', 'Adult', 'Attitude to Health', 'Caregivers', 'Cost of Illness', 'Employment', 'Family', 'Family Characteristics', 'Feasibility Studies', 'Female', 'Humans', 'Income', 'India', 'Male', 'Medical Indigency', 'Middle Aged', 'Pilot Projects', 'Poverty', 'Surveys and Questionnaires', 'Terminal Care']
20,712,463
[['F02.784.692.107'], ['M01.060.116'], ['F01.100.150', 'N05.300.150'], ['M01.085', 'M01.526.485.200', 'N02.360.200'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['N01.824.245'], ['F01.829.263', 'I01.880.853.150'], ['F01.829.263.315', 'I01.240.361', 'I01.880.853.150.423', ...
['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]']
0
1
0
0
1
1
0
0
1
0
0
1
1
1
A transcription-dependent increase in miniature EPSC frequency accompanies late-phase plasticity in cultured hippocampal neurons.
BACKGROUND: The magnitude and longevity of synaptic activity-induced changes in synaptic efficacy is quantified by measuring evoked responses whose potentiation requires gene transcription to persist for more than 2-3 hours. While miniature EPSCs (mEPSCs) are also increased in amplitude and/or frequency during long-ter...
['Action Potentials', 'Animals', 'Animals, Newborn', 'Blotting, Western', 'Cells, Cultured', 'Excitatory Postsynaptic Potentials', 'Hippocampus', 'Miniature Postsynaptic Potentials', 'Nerve Net', 'Neuronal Plasticity', 'Neurons', 'Patch-Clamp Techniques', 'Proto-Oncogene Proteins c-fos', 'Rats', 'Rats, Sprague-Dawley',...
19,788,723
[['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['B01.050'], ['B01.050.050.282'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251'], ['G04.580.887.249', 'G07.265.675.887.249', 'G07.265.880.750.199', 'G11.561.570.918.249', 'G11.561.830.750.199'], ['A...
['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Chemicals and Drugs [D]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Asymmetrical cleft palate.
Ten cases of asymmetrical cleft palate are reported. The pathogenesis, classification and management are discussed.
['Adolescent', 'Adult', 'Child', 'Child, Preschool', 'Cleft Palate', 'Female', 'Humans', 'Male', 'Speech', 'Surgery, Oral', 'Treatment Outcome']
8,705,097
[['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['M01.060.406.448'], ['C05.500.460.185', 'C05.660.207.540.460.185', 'C07.320.440.185', 'C07.465.525.185', 'C07.650.500.460.185', 'C07.650.525.185', 'C16.131.621.207.540.460.185', 'C16.131.850.500.460.185', 'C16.131.850.525.185'], ['B01.050.150.900.649.313.988.400.112....
['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]']
0
1
1
0
1
1
1
1
0
0
1
1
1
0
[Education of the medical student in first aid, emergency and disaster medicine--the Graz model].
In Austria emergency and disaster medicine is a young interdisciplinary subject. It is only a borderline discipline encompassing different medical subjects and was subdivided into emergency medicine for medical doctors only and first-aid for lay people and emergency technicians. In fact, since emergency medicine withou...
['Austria', 'Curriculum', 'Disasters', 'Education, Medical', 'Emergency Medicine', 'First Aid', 'Humans', 'Relief Work']
7,632,858
[['Z01.542.088'], ['I02.158'], ['N06.230.100'], ['I02.358.399'], ['H02.403.250'], ['E02.365.305'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.787.839', 'N06.230.100.300']]
['Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]']
0
1
0
0
1
0
0
1
1
0
0
0
1
1
Early implant placement following single-tooth extraction in the esthetic zone: biologic rationale and surgical procedures.
Early implant placement is one treatment option for implant therapy following single-tooth extraction in the anterior maxilla. The surgical technique presented here is characterized by tooth extraction without flap elevation, a 4- to 8-week soft tissue healing period, implant placement in a correct three-dimensional po...
['Absorbable Implants', 'Alveolar Ridge Augmentation', 'Bone Substitutes', 'Bone Transplantation', 'Collagen', 'Crowns', 'Dental Implantation, Endosseous', 'Dental Implants, Single-Tooth', 'Esthetics, Dental', 'Female', 'Follow-Up Studies', 'Guided Tissue Regeneration, Periodontal', 'Humans', 'Incisor', 'Maxilla', 'Mem...
18,990,995
[['E07.695.025'], ['E04.545.550.100', 'E06.645.550.100'], ['D25.130.325', 'J01.637.051.130.325'], ['E02.095.147.725.052', 'E04.555.130', 'E04.936.580.052'], ['D05.750.078.280', 'D12.776.860.300.250'], ['E06.780.346.250', 'E07.695.190.088'], ['E04.545.550.280.280', 'E04.650.230.500', 'E06.645.550.280.280', 'E06.780.314....
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Named Groups [M]']
1
1
0
1
1
0
1
0
0
1
0
1
1
0
Wild capuchin monkeys (Cebus libidinosus) use anvils and stone pounding tools.
We conducted an exploratory investigation in an area where nut-cracking by wild capuchin monkeys is common knowledge among local residents. In addition to observing male and female capuchin monkeys using stones to pound open nuts on stone "anvils," we surveyed the surrounding area and found physical evidence that monke...
['Animals', 'Behavior, Animal', 'Cebus', 'Cognition', 'Female', 'Food', 'Male', 'Motor Activity', 'Nuts']
15,580,579
[['B01.050'], ['F01.145.113'], ['B01.050.150.900.649.313.988.400.600.150.170.120'], ['F02.463.188'], ['G07.203.300', 'J02.500'], ['F01.145.632', 'G11.427.410.698'], ['A18.024.500.500', 'G07.203.300.700', 'J02.500.700']]
['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]']
1
1
0
0
0
1
1
0
0
1
0
0
0
0
Actions of quinine on the rat isolated rectum.
The actions of quinine on the rat isolated rectum was studied. Quinine (2.5 X 10(-5) - 2.5 X 10(-4) M) initiated rhythmic phasic contractions (RPC) which were prevented by verapamil, lanthanum, indomethacin or Ca2+-withdrawal, but were unaffected by tetrodotoxin, L-propranolol, phentolamine, or atropine. Higher quinine...
['Acetylcholine', 'Animals', 'Biological Transport', 'Calcium', 'Drug Interactions', 'Electric Stimulation', 'Female', 'In Vitro Techniques', 'Indomethacin', 'Male', 'Muscle, Smooth', 'Parasympathomimetics', 'Potassium Chloride', 'Quinine', 'Rats', 'Rats, Inbred Strains', 'Rectum', 'Sympathomimetics', 'Tetrodotoxin']
4,051,636
[['D02.092.211.111'], ['B01.050'], ['G03.143'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G07.690.773.968'], ['E05.723.402'], ['E05.481'], ['D03.633.100.473.420'], ['A02.633.570', 'A10.690.467'], ['D27.505.696.663.050.675'], ['D01.210.450.150.750', 'D01.745.625'], ['D03.132.206.719', 'D03.605.687.762', '...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
DUXAP8, a pseudogene derived lncRNA, promotes growth of pancreatic carcinoma cells by epigenetically silencing CDKN1A and KLF2.
BACKGROUND: Recent studies highlight pseudogene derived long non-coding RNAs (lncRNAs) as key regulators of cancer biology. However, few of them have been well characterized in pancreatic cancer. Here, we aimed to identify the association between pseudogene derived lncRNA DUXAP8 and growth of pancreatic cancer cells.ME...
['Aged', 'Animals', 'Cell Line, Tumor', 'Cell Proliferation', 'Cyclin-Dependent Kinase Inhibitor p21', 'Down-Regulation', 'Epigenesis, Genetic', 'Female', 'Heterografts', 'Humans', 'Kruppel-Like Transcription Factors', 'Male', 'Mice', 'Mice, Nude', 'Pseudogenes', 'RNA, Long Noncoding', 'Transfection']
30,367,681
[['M01.060.116.100'], ['B01.050'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.161.750', 'G07.345.249.410.750'], ['D12.644.360.225.500', 'D12.776.157.687.250', 'D12.776.167.187.500', 'D12.776.476.225.500', 'D12.776.624.776.355.500', 'D12.776.660.720.250'], ['G02.111.240', 'G05.308.200', 'G07.690.773.937'], ['G05.308....
['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
0
1
1
0
1
0
0
0
0
1
0
0
UHRF2 decreases H3K9ac expression by interacting with it through the PHD and SRA/YDG domain in HepG2 hepatocellular carcinoma cells.
Ubiquitin-like with PHD and ring finger domains 2 (UHRF2) is a multi-domain E3 ubiquitin ligase which is involved in epigenetic regulation and plays an essential role in tumorigenesis. However, the role of UHRF2 in histone H3 acetylation has not yet been fully elucidated and few studies have reported its role in hepato...
['Acetylation', 'Carcinoma, Hepatocellular', 'Hep G2 Cells', 'Histones', 'Humans', 'Liver Neoplasms', 'Lysine', 'Protein Binding', 'Protein Domains', 'Protein Transport', 'Sequence Deletion', 'Structure-Activity Relationship', 'Ubiquitin-Protein Ligases']
28,004,105
[['G02.111.012.052', 'G02.607.063.052', 'G03.040.052'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['A11.251.860.180.432', 'A11.436.348.500'], ['D12.776.157.687.485', 'D12.776.660.720.485', 'D12.776.664.469'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274....
['Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]']
1
1
1
1
0
0
1
0
0
0
0
0
0
0
Doctor! Will I be dry? Factors determining recurrence after vesicovaginal fistula repair.
OBJECTIVE: To evaluate various prognostic factors which determine outcome after surgical repair of vesicovaginal fistula.METHODS: The retrospective study was conducted at Koohi Goth Fistula Hospital, Karachi, and comprised data related to patients having undergone vesicovaginal fistula repair from January 2007 to June ...
['Adolescent', 'Adult', 'Aged', 'Female', 'Humans', 'Middle Aged', 'Pakistan', 'Prognosis', 'Recurrence', 'Retrospective Studies', 'Risk Factors', 'Treatment Outcome', 'Vesicovaginal Fistula']
26,338,740
[['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['Z01.252.245.723'], ['E01.789'], ['C23.550.291.937'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500.5...
['Named Groups [M]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]']
0
1
1
0
1
0
0
0
0
0
0
1
1
1
The harmonic scalpel versus electrocautery for parotidectomy: A meta - analysis.
OBJECTIVE: Parotidectomy is the most classic and unequivocal intervention for parotid neoplasm. The operative outcomes and postoperative complications of parotidectomy between harmonic scalpel and electrocautery gained more prominence in physician. In spite of much research work within the past years, there was an obvi...
['Blood Loss, Surgical', 'China', 'Electrocoagulation', 'Humans', 'Operative Time', 'Surgical Instruments']
30,954,384
[['C23.550.414.300', 'C23.550.505.300'], ['Z01.252.474.164'], ['E02.154.402', 'E04.014.170.402'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.614.374.500', 'N02.421.585.753.374.500'], ['E07.858.700']]
['Diseases [C]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]']
0
1
1
0
1
0
0
0
0
0
0
0
1
1
A case of medullomyoblastoma of cerebellopontine angle mimicking acoustic neuroma.
Medulloblastoma is a common malignant central nervous system neoplasm found mainly in children. One the contrary, medulloblastoma of the cerebellopontine angle, the location of the tumor is very unusual. This is the the first case of the medullomyoblastoma, a rare form of medulloblastoma, occurring in the cerebellopont...
['Adolescent', 'Cerebellar Neoplasms', 'Cerebellopontine Angle', 'Diagnosis, Differential', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Medulloblastoma', 'Neuroma, Acoustic']
15,344,215
[['M01.060.057'], ['C04.588.614.250.195.411.211', 'C10.228.140.211.500.200', 'C10.228.140.252.200', 'C10.551.240.250.400.300'], ['A08.186.211.132.810.428.200.462'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['C04.557.465.625.600.380.515', 'C04.557.465.625.600.590.500', 'C04....
['Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]']
1
1
1
0
1
0
0
0
0
0
0
1
0
0
Percutaneous ethanol injection for the treatment of hepatic tumors: indications, mechanism of action, technique, and efficacy.
Percutaneous injection of ethanol for treatment of hepatic tumors was first described by Sugiura et al. [1] in 1983. To date, reported experience with the procedure has focused mainly on therapy of hepatocellular carcinoma (HCC) [2-15], with little information available regarding its use in treating metastatic liver le...
['Carcinoma, Hepatocellular', 'Ethanol', 'Humans', 'Injections', 'Liver Neoplasms', 'Radiography, Interventional', 'Ultrasonography, Interventional']
7,998,542
[['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['D02.033.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['E01.370.350.700.725', 'E04.502.780'], ['E01.370.350.850.855', 'E04.502.890']]
['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
1
1
1
0
0
0
0
0
0
0
0
0
Preclinical evaluation of two real-time, reverse transcription-PCR assays for detection of the severe acute respiratory syndrome coronavirus.
We verified the analytical performance characteristics of a previously described real-time reverse transcription-PCR (RT-PCR) assay targeting the open reading frame (ORF) 1b region of the severe acute respiratory syndrome coronavirus (SARS-CoV) with RNA transcripts. We then compared it to a novel nucleocapsid gene real...
['Bronchoalveolar Lavage Fluid', 'Feces', 'Humans', 'Open Reading Frames', 'RNA, Viral', 'Regression Analysis', 'Reproducibility of Results', 'Reverse Transcriptase Polymerase Chain Reaction', 'SARS Virus', 'Severe Acute Respiratory Syndrome', 'Water Microbiology']
15,004,042
[['E05.927.100.500'], ['A12.459'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.335.760.640', 'G05.360.340.024.340.137.650'], ['D13.444.735.828'], ['E05.318.740.750', 'N05.715.360.750.695', 'N06.850.520.830.750'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['E05.393....
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Disciplines and Occupations [H]']
1
1
1
1
1
0
1
1
0
0
0
0
1
0
Capillary liquid chromatography/electrospray mass spectrometry for analysis of steroid sulfates in biological samples.
A new procedure for capillary liquid chromatography-electrospray (CLC-ES) mass spectrometry is described. Using this procedure, coupling of a CLC column to a low-flow-rate ES interface is made simple. A 5-cm precolumn and a 35-cm analytical column, both fused-silica capillaries with an i.d. of 100 microm and packed wit...
['Adult', 'Chromatography, High Pressure Liquid', 'Humans', 'Male', 'Microchemistry', 'Spectrometry, Mass, Electrospray Ionization', 'Steroids', 'Sulfates']
12,622,368
[['M01.060.116'], ['E05.196.181.400.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.196.620', 'H01.181.650'], ['E05.196.566.600'], ['D04.210.500'], ['D01.248.497.158.845', 'D01.875.800.800.850']]
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]']
0
1
0
1
1
0
0
1
0
0
0
1
0
0
Intraoral approach for nasal tip upturning.
BACKGROUND: The nose is an important landmark in facial beauty, and slight modifications lead to dramatic changes. The authors describe their surgical technique to upturn the tip of the nose with an intraoral approach sectioning the fibers of muscle depressor septi.METHODS: There were 14 patients (5 male and 9 female p...
['Adult', 'Facial Muscles', 'Female', 'Humans', 'Male', 'Mouth', 'Nerve Block', 'Photography', 'Rhinoplasty', 'Treatment Outcome']
22,777,460
[['M01.060.116'], ['A02.633.567.400', 'A14.363'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.456.505.631', 'A03.556.500', 'A14.549'], ['E03.155.086.711', 'E04.525.210.550'], ['E01.370.350.600', 'E05.712'], ['E02.218.755', 'E04.580.392.500', 'E04.680.650'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360...
['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
1
1
0
0
1
0
0
0
0
0
0
1
1
0
An audit of therapeutic drug monitoring procedures--use of theophylline assay services.
Monitoring therapy involving drugs exhibiting high intersubject variation and/or narrow therapeutic index has become more generally accepted in hospitals. This paper describes an audit conducted jointly by clinical pharmacists and clinical biochemists into the use and therapeutic value of a drug monitoring service in a...
['Adult', 'Aging', 'Australia', 'Chemistry, Clinical', 'Drug Therapy, Combination', 'Drug Utilization', 'Hospital Departments', 'Hospitals, General', 'Humans', 'Infant, Newborn', 'Theophylline']
6,715,561
[['M01.060.116'], ['G07.345.124'], ['Z01.639.100', 'Z01.678.100.373'], ['H01.181.341'], ['E02.319.310'], ['N04.452.706.477'], ['N02.278.216.500.968', 'N04.452.442.452.422'], ['N02.278.421.389'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['D03.132.960.751', 'D03.633.100.759.758.824.751']]
['Named Groups [M]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]']
0
1
0
1
1
0
1
1
0
0
0
1
1
1
Phytosynthesis of nanoscale ZnAl2O4 by using Sesamum (Sesamum indicum L.) optical and catalytic properties.
There is a growing concern for the development of alternative environment friendly sustainable methods for the preparation of nanomaterials. Phytosynthesis of nano zinc aluminate by a microwave method using high purity metal nitrates and Sesamum (Sesamum indicum L.) extract is reported in this work. Sesamum (Sesamum in...
['Aluminum Oxide', 'Catalysis', 'Microscopy, Electron, Scanning', 'Nanostructures', 'Sesamum', 'Spectrum Analysis', 'X-Ray Diffraction', 'Zinc']
24,266,227
[['D01.056.050', 'D01.650.550.050'], ['G02.130'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['J01.637.512'], ['B01.650.940.800.575.912.250.583.690.750'], ['E05.196.867'], ['E05.196.309.742', 'E05.196.822.950', 'G01.867.950', 'G02.965'], ['D01.268.556.940', 'D01.268.956.906', 'D01.552.544.940']]
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]']
0
1
0
1
1
0
1
0
0
1
0
0
0
0
Transient lumbar pain after 5% hyperbaric lignocaine spinal anaesthesia in patients having minor vascular surgery.
Transient lumbar pain has been reported to occur frequently in patients having surgery using 5% hyperbaric lignocaine for spinal anaesthesia. The incidence of transient lumbar pain is highest with this agent in patients having surgery in the lithotomy position and in outpatients. The aim of this audit was to determine ...
['Aged', 'Anesthesia, Spinal', 'Anesthetics, Local', 'Female', 'Humans', 'Leg', 'Lidocaine', 'Low Back Pain', 'Male', 'Prospective Studies', 'Vascular Surgical Procedures']
12,500,518
[['M01.060.116.100'], ['E03.155.086.331'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['D02.065.199.092.500', 'D02.092.146.113.092.500'], ['C23.888.592.612.107.400'], ['E05.318.372.500.750.625', 'N05.715.36...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]']
1
1
1
1
1
0
0
0
0
0
0
1
1
0
["Public health goals"--concepts this side of utopia? Berlin Public Health Research Organization--divided project "Goals and goal indicators for East and West Berlin Public Health"].
Objectives or targets for health have been presented by the World Health Organisation as well as a number of national health administrations. Health objectives are intended as guidelines attracting the commitment of decision makers and health professionals. As a "normative health indicator" a health objective should qu...
['Adult', 'Berlin', 'Cause of Death', 'Female', 'Goals', 'Health Priorities', 'Humans', 'Male', 'Middle Aged', 'Mortality', 'Public Health', 'Risk Factors', 'Social Change', 'Utopias']
7,620,244
[['M01.060.116'], ['Z01.433.128', 'Z01.542.315.182'], ['E05.318.308.985.550.250', 'N01.224.935.698.100', 'N06.850.505.400.975.550.250', 'N06.850.520.308.985.550.250'], ['F01.658.500'], ['N03.349.330', 'N05.300.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.550', 'N01.224....
['Named Groups [M]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]']
0
1
0
0
1
1
0
1
1
0
0
1
1
1
Effect of ischemia on nucleosides and bases in rat liver and hepatoma 3924A.
A high-pressure liquid chromatographic method was developed which achieved a separation and quantitation of 20 biologically important nucleosides and bases. The concentrations of pyrimidine nucleosides and bases, namely deoxycytidine, cytosine, cytidine, uracil, and uridine (22.6, 10.1, 5.2, 2.9, and 2.4 nmol/ml, respe...
['Animals', 'Chromatography, High Pressure Liquid', 'Erythrocytes', 'Ischemia', 'Liver', 'Liver Neoplasms, Experimental', 'Nucleosides', 'Purines', 'Pyrimidines', 'Rats', 'Rats, Inbred Strains', 'Time Factors']
3,581,061
[['B01.050'], ['E05.196.181.400.300'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['C23.550.513'], ['A03.620'], ['C04.588.274.623.460', 'C04.619.540', 'C06.301.623.460', 'C06.552.697.580', 'E05.598.500.496.750'], ['D09.408.595', 'D13.570'], ['D03.633.100.759'], ['D03.383.742'], ['B01.050.150.900.649.313.992.635...
['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]']
1
1
1
1
1
0
1
0
0
0
0
0
0
0
Outcomes of rectal resection following neoadjuvant therapy in the elderly: Can rectal cancer patients be too old for a neoadjuvant approach?
BACKGROUND: Neoadjuvant therapy has improved outcomes of resection for rectal carcinoma, however, there is limited data regarding its impact on elderly patients.METHODS: A retrospective review of 109 patients, 74 patients <70 years (Group 1) vs 35 elderly patients ? 70 years (Group 2), who underwent neoadjuvant therapy...
['Adenocarcinoma', 'Adult', 'Age Factors', 'Aged', 'Aged, 80 and over', 'Chemoradiotherapy, Adjuvant', 'Clinical Decision-Making', 'Female', 'Follow-Up Studies', 'Humans', 'Kaplan-Meier Estimate', 'Male', 'Middle Aged', 'Neoadjuvant Therapy', 'Proctectomy', 'Rectal Neoplasms', 'Retrospective Studies', 'Treatment Outcom...
29,162,219
[['C04.557.470.200.025'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.186.079.500', 'E02.319.164.500', 'E02.815.160.500'], ['E01.055'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.98...
['Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]']
0
1
1
0
1
0
0
0
0
0
0
1
1
0
Interactive effects of age and cerebral disease on cognitive performances.
A battery of mental tests was given to groups of younger (16--44 years) and older (48--60 years) control and cerebral diseased patients. Each patient in the younger cerebral diseased group was matched individually with an older cerebral diseased patient for type and site of lesion. Each patient with cerebral disease wa...
['Adolescent', 'Adult', 'Aging', 'Brain Diseases', 'Cognition', 'Humans', 'Intelligence Tests', 'Middle Aged']
75,954
[['M01.060.057'], ['M01.060.116'], ['G07.345.124'], ['C10.228.140'], ['F02.463.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F04.711.141.493'], ['M01.060.116.630']]
['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]']
0
1
1
0
0
1
1
0
0
0
0
1
0
0
Long-term results of the surgical treatment of syringohydromyelia.
Long-term results of 26 patients suffering from syringohydromyelia are reported. The patients underwent laminectomy and myelotomy with marsupialisation of the intracord cavity. Two different long term objective examinations have been performed demonstrating favorable results in 65% of patients at the first examination ...
['Adult', 'Female', 'Follow-Up Studies', 'Humans', 'Laminectomy', 'Male', 'Middle Aged', 'Spinal Cord', 'Syringomyelia']
6,731,055
[['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.718.563', 'E04.188.400', 'E04.525.450', 'E04.555.350'], ['M01.060.116.630'], ['A08.186.854'], ['C10.228.854.833']]
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]']
1
1
1
0
1
0
0
0
0
0
0
1
1
0
Molecular epidemiologic study of mitochondrial DNA mutations in patients with mitochondrial diseases in Taiwan.
We report an 8-year molecular study of mitochondrial DNA (mtDNA) mutations in patients with mitochondrial diseases in Taiwan. One hundred and seventy-seven patients met the diagnostic criteria of mitochondrial disease and were recruited into the study. The results showed that 32 patients, including 25 with mitochondria...
['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'DNA, Mitochondrial', 'Deafness', 'Diabetes Mellitus', 'Female', 'Humans', 'Infant', 'Leigh Disease', 'Male', 'Middle Aged', 'Mitochondrial Encephalomyopathies', 'Mutation', 'Optic Atrophies, Hereditary', 'Phenotype', 'Taiwan']
10,420,700
[['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['D13.444.308.283.225'], ['C09.218.458.341.186', 'C10.597.751.418.341.186', 'C23.888.592.763.393.341.186'], ['C18.452.394.750', 'C19.246'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.70...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]']
0
1
1
1
0
0
1
0
0
0
0
1
0
1
Trichomonas vaginalis: a possible foe to prostate cancer.
Prostate cancer (PCA) is the most common malignancy in men in USA, and the role of Trichomonas vaginalis (T. vag) in the development of PCA is still controversial. Clonogenic assay, PCNA staining, TUNEL staining and caspase-3 activity assay were used to investigate the in vitro role of T. vag in human prostate cancer. ...
['Apoptosis', 'Cell Growth Processes', 'Cell Line, Tumor', 'Cyclin-Dependent Kinase Inhibitor p21', 'Humans', 'Male', 'Prostatic Neoplasms', 'Proto-Oncogene Proteins c-bcl-2', 'Trichomonas vaginalis']
27,613,161
[['G04.146.954.035'], ['G04.161', 'G07.345.249.410'], ['A11.251.210.190', 'A11.251.860.180'], ['D12.644.360.225.500', 'D12.776.157.687.250', 'D12.776.167.187.500', 'D12.776.476.225.500', 'D12.776.624.776.355.500', 'D12.776.660.720.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.945.440.770', 'C12.294....
['Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]']
1
1
1
1
0
0
1
0
0
0
0
0
0
0
Avoidance of harm and anxiety: a role for the nucleus accumbens.
Active and passive avoidance behaviors involve either emitting or omitting a response to avoid potential harm. Both are key components in the etiology and maintenance of anxiety disorders, yet the neural circuitry that mediates avoidance is underexplored. Using functional magnetic resonance imaging greater hemodynamic ...
['Adult', 'Anxiety', 'Avoidance Learning', 'Female', 'Harm Reduction', 'Humans', 'Male', 'Nerve Net', 'Nucleus Accumbens', 'Punishment']
22,569,544
[['M01.060.116'], ['F01.470.132'], ['F02.463.425.097', 'F02.463.785.373.173'], ['F01.145.477'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.511'], ['A08.186.211.200.885.287.249.487.775.500'], ['F02.463.425.770.571', 'I01.880.630.716']]
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]']
1
1
0
0
0
1
0
0
1
0
0
1
0
0
Design and in vitro testing of a voice-producing element for laryngectomized patients.
A voice-producing element has been developed to improve speech quality after laryngectomy. The design process started with the formulation of a list of requirements. The lip principle has the best potential for fulfilling the requirements. A numerical model was made to find the optimal geometry of an element based on t...
['Laryngectomy', 'Larynx, Artificial', 'Prosthesis Design']
10,941,640
[['E04.580.369'], ['E07.695.450', 'E07.858.082.595'], ['E05.320.550', 'E07.695.680']]
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
0
0
0
1
0
0
0
0
0
0
0
0
0
Structure of mutagen nucleic acid complexes in solution. Proton chemical shifts in 9-aminoacridine complexes with dG-dC, dC-dG, and dA-dT-dG-dC-dA-dT.
The influence of self-complementary oligodeoxynucleotides on the chemical shifts of protons of the mutagenic acridine dye 9-aminoacridine has been measured. Upfield shifts indicative of intercalative binding are found in the cases of dG-dC, dC-dG, and dA-dT-dG-dC-dA-dT but not in dA-dT. Geometries for the complexes tha...
['Acridines', 'Kinetics', 'Magnetic Resonance Spectroscopy', 'Mutagens', 'Nucleic Acid Conformation', 'Oligodeoxyribonucleotides', 'Oligonucleotides', 'Structure-Activity Relationship']
687,569
[['D03.633.300.046'], ['G01.374.661', 'G02.111.490'], ['E05.196.867.519'], ['D27.888.569.468'], ['G02.111.570.820.486', 'G05.360.580'], ['D13.695.578.424.450'], ['D13.695.578.424'], ['G02.111.830', 'G07.690.773.997']]
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
0
0
1
1
0
1
0
0
0
0
0
0
0
Reversible cerebral vasoconstriction syndrome is a rare cause of stroke after carotid endarterectomy.
Neurologic events after carotid endarterectomy (CEA) require prompt diagnosis and management to avoid potentially catastrophic sequelae. This report describes a 69-year-old gentleman who underwent a left CEA for a high-grade asymptomatic carotid stenosis with concomitant contralateral carotid occlusion. He had transien...
['Aged', 'Carotid Stenosis', 'Cerebral Angiography', 'Cerebral Arteries', 'Computed Tomography Angiography', 'Endarterectomy, Carotid', 'Humans', 'Magnetic Resonance Angiography', 'Male', 'Stroke', 'Treatment Outcome', 'Vasoconstriction', 'Vasodilator Agents', 'Vasospasm, Intracranial']
26,924,717
[['M01.060.116.100'], ['C10.228.140.300.200.360', 'C14.907.137.230', 'C14.907.253.123.360'], ['E01.370.350.578.937.180', 'E01.370.350.700.060.180', 'E01.370.350.700.560.180', 'E01.370.370.050.180', 'E01.370.376.537.750.180', 'E05.629.937.180'], ['A07.015.114.228'], ['E01.370.350.350.810.335', 'E01.370.350.567.250', 'E0...
['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]']
1
1
1
1
1
0
1
0
0
0
0
1
1
0
The Well-of-the-Well system: an efficient approach to improve embryo development.
Transfer of human embryos at the blastocyst stage may offer considerable benefits including an increased implantation rate and a decreased risk of multiple pregnancies; however, blastocyst culture requires an efficient and reliable in-vitro embryo culture system. In this study, the effect of the Well-of-the-Well (WOW) ...
['Adult', 'Animals', 'Blastocyst', 'Case-Control Studies', 'Embryo Culture Techniques', 'Female', 'Fertilization in Vitro', 'Humans', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Mice, Inbred DBA', 'Oocytes', 'Pregnancy', 'Pregnancy Outcome', 'Pregnancy Rate', 'Sperm Injections, Intracytoplasmic', 'Swine']
18,616,894
[['M01.060.116'], ['B01.050'], ['A16.254.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.481.500.468'], ['E02.875.800.750', 'E05.820.800.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.0...
['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]']
1
1
0
0
1
0
1
0
0
0
0
1
1
0
Long-Term Outcomes of Upper Eyelid Loading with Platinum Segment Chains for Lagophthalmos: An Adjustable Approach.
PURPOSE: This article reports the outcomes of a 5-year series of individually sutured platinum segment chains for upper eyelid loading.DESIGN: Consecutive case series.METHODS: Platinum segments of 0.4 and 0.2 g were assembled to create the desired weight and were placed in a supratarsal location after levator aponeuros...
['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Biocompatible Materials', 'Blinking', 'Child', 'Child, Preschool', 'Eyelid Diseases', 'Eyelids', 'Female', 'Follow-Up Studies', 'Humans', 'Infant', 'Male', 'Middle Aged', 'Patient Satisfaction', 'Platinum', 'Prostheses and Implants', 'Prosthesis Implantation', 'Qual...
31,765,627
[['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['G11.561.731.127', 'G14.152'], ['M01.060.406'], ['M01.060.406.448'], ['C11.338'], ['A01.456.505.420.504', 'A09.371.337'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.8...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Anthropology, Education...
1
1
1
1
1
1
1
0
1
1
0
1
1
0
Total iron-overload measurement in the human liver region by the magnetic iron detector.
An accurate assessment of body iron accumulation is essential for the diagnosis and therapy of iron overload in diseases, such as hemochromatosis, thalassemia and other forms of severe anemias. The magnetic iron detector (MID) is a room-temperature susceptometer, which measures the total iron overload in the liver. Sin...
['Abdomen', 'Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Female', 'Humans', 'Iron', 'Iron Overload', 'Linear Models', 'Liver', 'Magnetics', 'Male', 'Middle Aged', 'Signal Processing, Computer-Assisted']
20,562,030
[['A01.923.047'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.268.556.412', 'D01.268.956.287', 'D01.552.544.412'], ['C18.452.565.500'], ['E05.318.740.500.500', 'E05.318.740.750.425', 'E05.599.835.750', 'N05.715.360.750.530.460', ...
['Anatomy [A]', 'Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]']
1
1
1
1
1
0
0
1
0
0
1
1
1
0
A telephone reminder intervention to improve breast screening information and access.
OBJECTIVES: In the UK, women aged 50-70 are offered breast cancer screening every three years. Screening participation rates in London have been particularly low. Low rates have been associated with low socio-economic status, and some ethnic groups have been observed to be underserved by cancer screening. This paper re...
['Aged', 'Breast Neoplasms', 'Cultural Diversity', 'Early Detection of Cancer', 'Ethnic Groups', 'Female', 'Health Promotion', 'Health Services Accessibility', 'Humans', 'Information Dissemination', 'London', 'Middle Aged', 'Program Evaluation', 'Reminder Systems', 'Socioeconomic Factors', 'State Medicine', 'Telephone'...
25,443,131
[['M01.060.116.100'], ['C04.588.180', 'C17.800.090.500'], ['I01.076.201.450.350', 'I01.880.853.100.450'], ['E01.390.500'], ['M01.686.754', 'N01.224.317'], ['I02.233.332.445', 'N02.421.726.407.579'], ['N04.590.374.350', 'N05.300.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.143.443'], ['Z01.433.553', 'Z0...
['Named Groups [M]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Geographicals [Z]']
0
1
1
0
1
0
0
0
1
0
1
1
1
1
Epstein-Barr virus-associated lymphoproliferative syndromes: studies in two European families.
The X-linked lymphoproliferative syndrome (XLP), also known as Duncan's disease, is an X-linked recessive disorder that is characterized by the inability of affected individuals to mount a sufficient immune response to Epstein-Barr virus (EBV). After EBV primary infection, male family members suffer from severe infecti...
['Agammaglobulinemia', 'Anemia, Aplastic', 'Child', 'Child, Preschool', 'Female', 'Genetic Linkage', 'Herpesvirus 4, Human', 'Humans', 'Infant', 'Infectious Mononucleosis', 'Lymphoproliferative Disorders', 'Male', 'Pedigree']
1,646,073
[['C15.378.147.142', 'C15.604.515.032', 'C20.673.088'], ['C15.378.071.085', 'C15.378.190.223.250'], ['M01.060.406'], ['M01.060.406.448'], ['G05.348'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C01.925.256.466.31...
['Diseases [C]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
0
1
1
0
1
0
1
0
0
0
0
1
0
0
Effects of cognitive-behavioural therapy on anxiety for children with high-functioning autistic spectrum disorders.
INTRODUCTION: Children with autistic spectrum disorders (ASD) often exhibit one or more comorbid disorders, including anxiety, disruptive behaviour, mental retardation, and depression. Various studies have documented the effectiveness of cognitive-behavioural therapy (CBT) in treating children with anxiety. Although st...
['Adolescent', 'Anxiety Disorders', 'Autistic Disorder', 'Child', 'Child Development Disorders, Pervasive', 'Cognitive Behavioral Therapy', 'Female', 'Humans', 'Male', 'Pilot Projects', 'Prevalence', 'Psychological Tests', 'Psychometrics', 'Risk Factors', 'Singapore', 'Treatment Outcome']
18,363,003
[['M01.060.057'], ['F03.080'], ['F03.625.164.113.500'], ['M01.060.406'], ['F03.625.164'], ['F04.754.137.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.750', 'E05.337.737', 'N05.715.360.330.720', 'N06.850.520.450.720'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.75...
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]']
0
1
0
0
1
1
0
0
0
0
0
1
1
1
Single nucleotide polymorphisms 5' upstream the coding region of the NEIL2 gene influence gene transcription levels and alter levels of genetic damage.
NEIL2 (EC 4.2.99.18), a mammalian DNA glycosylase and ortholog of the bacterial Fpg/Nei, excises oxidized DNA lesions from bubble or single-stranded structures, suggesting its involvement in transcription-coupled DNA repair. Because base excision repair (BER) proteins act collectively and in a progressive fashion, thei...
["5' Flanking Region", 'Adult', 'Aged', 'Base Sequence', 'DNA Damage', 'DNA Glycosylases', 'DNA-(Apurinic or Apyrimidinic Site) Lyase', 'Ethnic Groups', 'Female', 'Gene Dosage', 'Genetic Predisposition to Disease', 'Humans', 'Lymphocytes', 'Male', 'Middle Aged', 'Molecular Sequence Data', 'Mutation', 'Polymorphism, Sin...
18,651,651
[['G05.360.340.024.220.282', 'G05.360.340.024.340.137.295'], ['M01.060.116'], ['M01.060.116.100'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.200'], ['D08.811.074.249', 'D08.811.277.450.430.099'], ['D08.811.074.750', 'D08.811.520.241.225'], ['M01.686.754', 'N01.224.317'], ['G05.380.350'], ['C23.55...
['Phenomena and Processes [G]', 'Named Groups [M]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]']
1
1
1
1
0
0
1
0
0
0
1
1
1
0
Dietary flavonoid intakes and risk of type 2 diabetes in US men and women.
BACKGROUND: Data from mechanistic studies support a beneficial effect of specific flavonoids on insulin sensitivity. However, few studies have evaluated the relation between intakes of different flavonoid subclasses and type 2 diabetes.OBJECTIVE: The objective was to evaluate whether dietary intakes of major flavonoid ...
['Adult', 'Aged', 'Anthocyanins', 'Blueberry Plants', 'Cohort Studies', 'Diabetes Mellitus, Type 2', 'Diet', 'Female', 'Flavonoids', 'Follow-Up Studies', 'Fruit', 'Humans', 'Incidence', 'Male', 'Malus', 'Middle Aged', 'Prospective Studies', 'Pyrus', 'Risk', 'United States']
22,357,723
[['M01.060.116'], ['M01.060.116.100'], ['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['B01.650.940.800.575.912.250.341.937.774.249'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C18.452.394.750.149', 'C19.246.300'], ['G07.203.650.240']...
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]']
1
1
1
1
1
0
1
0
0
1
0
1
1
1
Human endothelial cell growth and coagulant function varies with respect to interfacial properties of polymeric substrates.
The in vitro coagulant function of human aortic endothelial cells (HAECs) was investigated when grown on a series of polymer surfaces that ranged from hydrophobic to hydrophilic. The polymer interface materials were prepared by radiofrequency plasma polymerization from hexamethyl-disilazane, gamma-butyrolactone, and N-...
['Aorta, Thoracic', 'Blood Coagulation', 'Cell Division', 'Cells, Cultured', 'Chemical Phenomena', 'Chemistry, Physical', 'Endothelium, Vascular', 'Epoprostenol', 'Fibronectins', 'Hemolysis', 'Humans', 'Polymers', 'Prostheses and Implants', 'Surface Tension', 'Tissue Plasminogen Activator', 'von Willebrand Factor']
9,019,486
[['A07.015.114.056.372'], ['G09.188.390.150'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251'], ['G02'], ['H01.181.529'], ['A07.015.700.500', 'A10.272.491.355'], ['D10.251.355.255.550.550.500', 'D23.469.050.175.725.550.500'], ['D12.776.377.715.390', 'D12.776.395.550.350', 'D12.776....
['Anatomy [A]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
1
1
1
0
1
1
0
1
0
0
0
0
Hyperbaric oxygenation combined with nifedipine treatment for recent-onset retinal artery occlusion.
We describe the results of early hyperbaric oxygenation combined with nifedipine treatment for central retinal artery occlusion, and explain the results pathophysiologically. We report four cases in which hyperbaric oxygenation therapy was applied in combination with nifedipine, eyeball massage, and glycerol for the tr...
['Adult', 'Aged', 'Combined Modality Therapy', 'Female', 'Follow-Up Studies', 'Glycerol', 'Humans', 'Hyperbaric Oxygenation', 'Male', 'Massage', 'Middle Aged', 'Nifedipine', 'Retinal Artery Occlusion', 'Time Factors', 'Visual Acuity', 'Visual Fields']
8,353,436
[['M01.060.116'], ['M01.060.116.100'], ['E02.186'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['D02.033.800.875.500', 'D09.853.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.880.690.490'], ['E02.190.599.750.750', 'E02.779.867.880.750', 'E02.831.535.867...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]']
0
1
1
1
1
1
1
0
0
0
0
1
1
0
Metabolism and disposition of the dipeptidyl peptidase IV inhibitor teneligliptin in humans.
1. The absorption, metabolism and excretion of teneligliptin were investigated in healthy male subjects after a single oral dose of 20 mg [(14)C]teneligliptin. 2. Total plasma radioactivity reached the peak concentration at 1.33 h after administration and thereafter disappeared in a biphasic manner. By 216 h after admi...
['Absorption', 'Adult', 'Area Under Curve', 'Carbon Radioisotopes', 'Chromatography, High Pressure Liquid', 'Cytochrome P-450 CYP3A', 'Dipeptidyl-Peptidase IV Inhibitors', 'Feces', 'Humans', 'Male', 'Mass Spectrometry', 'Middle Aged', 'Models, Biological', 'Molecular Structure', 'Oxygenases', 'Pyrazoles', 'Scintillatio...
23,855,261
[['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['M01.060.116'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['D01.268.150.075.328', 'D01.496.123.328', 'D01.496.749.154'], ['E05.196.181.400.300'], ['D08.244.453.860.500', 'D08.811.682.662.582.353', 'D08.811.682.690...
['Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]']
1
1
0
1
1
0
1
0
0
0
0
1
1
0
Developing a stable bilateral model of parkinsonism in rhesus monkeys.
The non-human primate models of Parkinson's disease which have been developed using the neurotoxin MPTP (1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine) have proven to be either unstable or variable, or to display only a limited subset of parkinsonian features. The present study examined a new two-stage lesion approach i...
['1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine', 'Animals', 'Carbidopa', 'Carotid Arteries', 'Disease Models, Animal', 'Dose-Response Relationship, Drug', 'Dyskinesia, Drug-Induced', 'Feeding Behavior', 'Female', 'Injections, Intra-Arterial', 'Levodopa', 'Macaca mulatta', 'Motor Activity', 'Parkinson Disease, Secondary...
8,433,810
[['D03.383.725.450'], ['B01.050'], ['D02.092.311.200.538.200', 'D02.442.200', 'D02.455.426.559.389.657.166.175.200.538.200'], ['A07.015.114.186'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['G07.690.773.875', 'G07.690.936.500'], ['C10.228.662.262.500', 'C10.597.350.275', 'C10.720.312', 'C23.888.592.350.275', 'C25....
['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]']
1
1
1
1
1
1
1
0
0
0
0
0
0
0
Improved production and purification of interferon-alpha-4a using a T7 RNA polymerase expression system.
An improved method for the synthesis and purification of human interferon-alpha-4a is presented. Interferon-alpha-4a was prepared using a T7 RNA polymerase expression system, where it was expressed from the vector pET-3a. Biologically active interferon-alpha-4a was isolated from the E. coli cells and purified using pro...
['Amino Acid Sequence', 'Antibodies, Monoclonal', 'Base Sequence', 'Blotting, Western', 'Chromatography, Affinity', 'Chromatography, Ion Exchange', 'DNA-Directed RNA Polymerases', 'Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Humans', 'Interferon Type I', 'Interferon-alpha', 'Molecular Sequence Data', 'Po...
1,456,949
[['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E05.196.181.400.17...
['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]']
0
1
0
1
1
0
1
0
0
0
1
0
0
0
Development of an algorithm to detect methotrexate wrong frequency error using computerized health care data.
PURPOSE: We validated an algorithm to detect frequency errors in computerized healthcare data and estimated the incidence of these errors in an integrated healthcare system.METHODS: We applied Sentinel System analytic tools on the electronic health records of Kaiser Permanente, Northern California, January 1, 2010, thr...
['Administration, Oral', 'Algorithms', 'Antidotes', 'Antirheumatic Agents', 'Arthritis, Rheumatoid', 'California', 'Clinical Coding', 'Delivery of Health Care, Integrated', 'Drug Administration Schedule', 'Drug Overdose', 'Electronic Health Records', 'Female', 'Humans', 'Incidence', 'International Classification of Dis...
31,410,932
[['E02.319.267.100'], ['G17.035', 'L01.224.050'], ['D27.505.696.706.037', 'D27.720.799.037'], ['D27.505.954.329'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['Z01.107.567.875.580.200', 'Z01.107.567.875.760.200'], ['N04.452.758.708.200.400.500', 'N04.452.859.564.274', 'N05.715.360.300.715.500...
['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]']
0
1
1
1
1
0
1
0
0
0
1
1
1
1
Topiramate for abnormal eating behaviour in frontotemporal dementia.
Topiramate is a sulfamate-substituted monosaccharide anticonvulsant that is associated with anorexia and weight loss and has been used to treat binge eating disorder and bulimia nervosa. This report describes a man with frontotemporal dementia, behavioural variant, associated with abnormal eating behaviour which appear...
['Adult', 'Anticonvulsants', 'Binge-Eating Disorder', 'Frontotemporal Dementia', 'Fructose', 'Humans', 'Male', 'Topiramate']
23,548,883
[['M01.060.116'], ['D27.505.954.427.080'], ['F03.400.188'], ['C10.228.140.380.266.299', 'C10.574.950.300.299', 'C18.452.845.800.300.299', 'F03.615.400.380.299'], ['D09.947.875.359.250', 'D09.947.875.465.354'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D09.947.875.359.250.500', 'D09.947.875.465.354.500']]
['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]']
0
1
1
1
0
1
0
0
0
0
0
1
0
0
[Partial and total joint replacement in femur head necrosis].
In literature, the results of hip arthroplasty in patients with avascular osteonecrosis of the femoral head vary. The main reason may be the nonhomogeneous patient groups concerning etiology of the femoral head necrosis (FHN). Analyzing the results of hip endoprosthesis in relation to the etiology of FHN leads to the a...
['Adult', 'Arthroplasty, Replacement, Hip', 'Female', 'Femur Head Necrosis', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Prosthesis Design', 'Prosthesis Failure', 'Radiography', 'Reoperation', 'Risk Factors']
10,875,139
[['M01.060.116'], ['E04.555.110.110.110', 'E04.650.110.110', 'E04.680.101.110.110'], ['C05.116.852.175', 'C23.550.717.732.368'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.767'], ['E05.320.550...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]']
0
1
1
0
1
0
0
0
0
0
0
1
1
0
Predicting quality of life after breast cancer surgery using ANN-based models: performance comparison with MR.
PURPOSE: The goal was to develop models for predicting long-term quality of life (QOL) after breast cancer surgery.METHODS: Data were obtained from 203 breast cancer patients who completed the SF-36 health survey before and 2 years after surgery. Two of the models used to predict QOL after surgery were artificial neura...
['Breast Neoplasms', 'Female', 'Follow-Up Studies', 'Humans', 'Models, Statistical', 'Neural Networks, Computer', 'Quality of Life', 'Regression Analysis', 'Time Factors']
23,203,653
[['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['G17.485', 'L01.224.050.375.605'], ['I01.800', 'K01.752.400....
['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]']
0
1
1
0
1
0
1
0
1
0
1
0
1
0
Degradation of oxytetracycline under autotrophic nitrifying conditions in a membrane aerated biofilm reactor and community fingerprinting.
Pharmaceuticals in waterbodies are a growing concern due to their extensive uses and adverse effects on aquatic life. Oxytetracycline (OTC) is one of tetracycline antibiotic group used for treatment of animals and humans. This study evaluates the simultaneous oxidation of OTC and ammonium under autotrophic nitrifying c...
['Ammonium Compounds', 'Anti-Bacterial Agents', 'Bacteria', 'Biofilms', 'Bioreactors', 'Membranes, Artificial', 'Nitrification', 'Oxidation-Reduction', 'Oxytetracycline', 'RNA, Ribosomal, 16S', 'Water Pollutants, Chemical']
29,803,031
[['D01.625.062'], ['D27.505.954.122.085'], ['B03'], ['A20.593', 'G06.120'], ['E07.115', 'J01.897.120.115'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['G02.111.587.500', 'G02.607.560.500', 'G16.500.768.500'], ['G02.700', 'G03.295.531'], ['D02.455.426.559.847.562.900.600', 'D04.615.562.900.600'], ['D13.444.735....
['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]']
1
1
0
1
1
0
1
0
0
1
0
0
0
0
Stochastic model for tumor control probability: effects of cell cycle and (a)symmetric proliferation.
BACKGROUND: Estimating the required dose in radiotherapy is of crucial importance since the administrated dose should be sufficient to eradicate the tumor and at the same time should inflict minimal damage on normal cells. The probability that a given dose and schedule of ionizing radiation eradicates all the tumor cel...
['Cell Cycle', 'Cell Proliferation', 'Humans', 'Neoplasms', 'Probability', 'Stochastic Processes']
25,416,304
[['G04.144'], ['G04.161.750', 'G07.345.249.410.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04'], ['E05.318.740.600', 'G17.680', 'N05.715.360.750.625', 'N06.850.520.830.600'], ['E05.318.740.996', 'G17.830', 'N05.715.360.750.770', 'N06.850.520.830.996']]
['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]']
0
1
1
0
1
0
1
0
0
0
0
0
1
0
Indicator-based systems of performance management in the National Health Service: a comparison of the perceptions of local- and national-level managers.
Historically, the UK Government has policed the use of National Health Service (NHS) resources through the centralization of control. With the majority of resource-draining decisions being taken by clinicians, however, professional financial accountability is becoming more important within the NHS management structure....
['Administrative Personnel', 'Conflict, Psychological', 'Efficiency, Organizational', 'Health Care Rationing', 'Health Services Research', 'Humans', 'Management Audit', 'Organizational Objectives', 'Perception', 'Quality Indicators, Health Care', 'Scotland', 'State Medicine']
11,184,003
[['M01.526.070'], ['F01.658.209'], ['N04.452.209.500'], ['I01.261.750.500', 'N03.349.270', 'N05.300.430.375'], ['H01.770.644.145.360', 'N03.349.380', 'N05.425'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.452.500'], ['N04.452.615'], ['F02.463.593'], ['N04.761.789', 'N05.715.760'], ['Z01.542.363.766'], ['N03...
['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]']
0
1
0
0
0
1
0
1
1
0
0
1
1
1
Sticky-trapping biting midges (Culicoides spp.) alighting on cattle and sheep: effects of trap colour and evidence for host preference.
Sticky traps were mounted on heifers and sheep to assess Culicoides spp. (Diptera: Ceratopogonidae) host preference. Initially, four coloured 200-cm(2) sticky traps (white, clear, yellow and blue) were attached to the backs of each of ten Friesian heifers that were released into open pasture for 24 h, repeated on six o...
['Animals', 'Cattle', 'Ceratopogonidae', 'Color', 'Entomology', 'Female', 'Host Specificity', 'Insect Vectors', 'Sheep', 'Sheep, Domestic']
24,913,430
[['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['B01.050.500.131.617.720.500.500.750.712.500.500'], ['G01.590.540.199'], ['H01.158.273.943.409'], ['G06.462.380', 'G16.527.200.380'], ['N06.850.335.188.100.500', 'N06.850.520.203.375.100.500'], ['B01.050.150.900.649.313.500.380.791'], ['B01.050.150.900.649.313.500...
['Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Health Care [N]']
0
1
0
0
0
0
1
1
0
0
0
0
1
0
Activated monocytes induce smooth muscle cell death: role of macrophage colony-stimulating factor and cell contact.
BACKGROUND: Plaque disruption is the inciting event for coronary thrombosis and acute coronary syndromes. Multiple factors influence plaque rupture, including the loss of vascular smooth muscle cells (VSMCs). We hypothesized that monocytes/macrophages (MMs) activated by macrophage colony-stimulating factor (M-CSF) are ...
['Abciximab', 'Antibodies, Monoclonal', 'Apoptosis', 'Cell Adhesion', 'Cells, Cultured', 'Coculture Techniques', 'Coronary Artery Disease', 'Coronary Thrombosis', 'Dose-Response Relationship, Drug', 'Humans', 'Immunoglobulin Fab Fragments', 'Interleukin-1', 'Macrophage Colony-Stimulating Factor', 'Macrophage-1 Antigen'...
11,790,697
[['D12.644.541.500.650.125', 'D12.776.124.486.485.114.224.060.125', 'D12.776.124.486.485.680.650.125', 'D12.776.124.790.651.114.224.060.125', 'D12.776.124.790.651.680.650.125', 'D12.776.377.715.548.114.224.200.125', 'D12.776.377.715.548.680.650.125'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12....
['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]']
1
1
1
1
1
0
1
0
0
0
0
0
0
0
[Association of health literacy with health management among diabetics].
OBJECTIVE: To understand status of health literacy among diabetics and their health management behaviors, and analyze the relationship of health literacy and health management.METHODS: A two-staged cluster randomized sampling method was used to investigate 1 130 diabetics in Beijing, Ningbo and Xiamen from October to N...
['Aged', 'Blood Glucose Self-Monitoring', 'Diabetes Mellitus', 'Female', 'Health Behavior', 'Health Literacy', 'Humans', 'Logistic Models', 'Male', 'Medication Adherence', 'Middle Aged', 'Surveys and Questionnaires']
25,388,469
[['M01.060.116.100'], ['E01.370.225.124.100.105', 'E01.370.374.100', 'E01.370.520.100', 'E02.900.950.500', 'E05.200.124.100.105'], ['C18.452.394.750', 'C19.246'], ['F01.145.488'], ['I02.233.332.186.500', 'L01.143.450.500', 'N02.421.726.407.229.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.52...
['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Information Science [L]', 'Health Care [N]', 'Organisms [B]']
0
1
1
0
1
1
0
0
1
0
1
1
1
0
Di-(2-ethylhexyl)adipate: absorption, autoradiographic distribution and elimination in mice and rats.
Whole-body autoradiography was used to study the tissue distribution of the plasticizer di-(2-ethylhexyl) adipate (DEHA), labelled in the acid [carbonyl-14C] or alcohol [2-ethylhexyl-1-14C]moiety, after iv or ig administration to male mice and rats and pregnant mice. With both DEHA preparations, during the first 24 hr ...
['Adipates', 'Animals', 'Autoradiography', 'Bile', 'Female', 'Intestinal Absorption', 'Male', 'Mice', 'Plasticizers', 'Pregnancy', 'Rats', 'Rats, Inbred Strains', 'Tissue Distribution']
3,583,157
[['D02.241.081.337.052'], ['B01.050'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['A12.200.087'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500', 'G07.690.725.015.500.374.500', 'G10.261.353.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['D27.720.760'], ['G08.686.784.769'...
['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]']
1
1
0
1
1
0
1
0
0
0
0
0
0
0
Chronic leg ulceration--the hidden epidemic.
Despite advances in our understanding of wound repair processes and improved pharmaceuticals, chronic leg ulceration continues to be a burden on the Australian health dollar. The simple management protocol presented here would considerably improve this unsatisfactory situation.
['Chronic Disease', 'Humans', 'Leg Ulcer']
7,968,734
[['C23.550.291.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C17.800.893.592']]
['Diseases [C]', 'Organisms [B]']
0
1
1
0
0
0
0
0
0
0
0
0
0
0
TCR gene rearrangements and expression of the pre-T cell receptor complex during human T-cell differentiation.
Recent studies have identified several populations of progenitor cells in the human thymus. The hematopoietic precursor activity of these populations has been determined. The most primitive human thymocytes express high levels of CD34 and lack CD1a. These cells acquire CD1a and differentiate into CD4(+)CD8(+) through C...
['CD4-Positive T-Lymphocytes', 'CD8-Positive T-Lymphocytes', 'Cell Differentiation', 'Child, Preschool', 'Gene Rearrangement, T-Lymphocyte', 'Gene Rearrangement, beta-Chain T-Cell Antigen Receptor', 'Gene Rearrangement, delta-Chain T-Cell Antigen Receptor', 'Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor', 'Hu...
10,216,100
[['A11.118.637.555.567.569.200', 'A15.145.229.637.555.567.569.200', 'A15.382.490.555.567.569.200'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['G04.152'], ['M01.060.406.448'], ['G05.344.801', 'G12.500.287'], ['G05.344.801.211', 'G12.500.287.211'], ['G05.344.801.2...
['Anatomy [A]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]']
1
1
0
1
1
0
1
0
0
0
0
1
0
0
[Determination of electrical parameters of the membrane of human amniotic epithelial cells in vitro].
Electrical parameters determination of epithelial amniotic cells membrane shows that the temperature increase alters membrane potential and input resistance, that the transcellular pathway of monovalent cations is less important than the paracellular pathway and that there is an intercellular electrical coupling.
['Amnion', 'Epithelium', 'Female', 'Humans', 'In Vitro Techniques', 'Membrane Potentials', 'Pregnancy', 'Temperature']
6,459,818
[['A10.615.284.277', 'A16.254.750.277'], ['A10.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.481'], ['G01.154.535', 'G04.580', 'G07.265.675', 'G11.561.570'], ['G08.686.784.769'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']]
['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]']
1
1
0
0
1
0
1
0
0
0
0
0
1
0
Neutrophil to lymphocyte count ratio as an early indicator of blood stream infection in the emergency department.
OBJECTIVES: Early identification of patients with blood stream infection (BSI), especially bacteraemia, is important as prompt treatment improves outcome. The initial stages of severe infection may be characterised by increased numbers of neutrophils in the peripheral blood and depression of the lymphocyte count (LC). ...
['Adult', 'Aged', 'Bacteremia', 'Biomarkers', 'C-Reactive Protein', 'Early Diagnosis', 'Emergency Service, Hospital', 'Female', 'Humans', 'Leukocyte Count', 'Lymphocyte Count', 'Male', 'Middle Aged', 'Neutrophils', 'Predictive Value of Tests', 'ROC Curve', 'Retrospective Studies', 'Sensitivity and Specificity']
25,183,249
[['M01.060.116'], ['M01.060.116.100'], ['C01.150.252.100', 'C01.757.100', 'C23.550.470.790.500.100'], ['D23.101'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['E01.390'], ['N02.278.216.500.968.336', 'N02.421.297.195', 'N04.452.442.452.422.336'], ['B01.050.150.900.649.313.988.400.112.400.400'], [...
['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]']
1
1
1
1
1
0
1
0
0
0
0
1
1
0
Algorithm for the treatment of external nasal valve insufficiency.
INTRODUCTION: Nasal obstruction is one of the most prevalent complaints in the population. The main causes of nasal obstruction are inflammatory, infectious or anatomical alterations. Anatomical alterations include nasal septum deviation, turbinate hypertrophy, and nasal valve insufficiency (external and/or internal). ...
['Algorithms', 'Humans', 'Nasal Obstruction', 'Nasal Septum', 'Nose Deformities, Acquired', 'Rhinoplasty']
31,126,741
[['G17.035', 'L01.224.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.460.525', 'C08.618.846.185.525', 'C09.603.525'], ['A04.531.591'], ['C08.460.619', 'C09.603.619'], ['E02.218.755', 'E04.580.392.500', 'E04.680.650']]
['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]']
1
1
1
0
1
0
1
0
0
0
1
0
0
0
Lactate dehydrogenase isoenzyme transitions during skeletal differentiation in the mouse embryo.
(1) In the mouse embryo there are changes in lactate dehydrogenase activity and isoenzyme pattern during the differentiation of cartilage and bone. (2) The specific activity of lactate dehydrogenase rises during chondrogenesis and falls during osteogenesis. (3) Identical isoenzyme transitions occur in parallel in both ...
['Aging', 'Animals', 'Animals, Newborn', 'Bone and Bones', 'Cartilage', 'Female', 'Isoenzymes', 'L-Lactate Dehydrogenase', 'Mice', 'Muscles', 'Pregnancy', 'Time Factors']
553,938
[]
[]
0
0
0
0
0
0
0
0
0
0
0
0
0
0
Effectiveness of Psychological Adaptation Model of Mental Health Nursing for nurse survivors experiencing post-earthquake disaster post-traumatic stress syndrome.
OBJECTIVE: The study to assess the effectiveness of psychological adaptation model of mental health nursing for nurse survivors experiencing post-earthquake post-traumatic stress syndrome (PTSS).METHOD: This study used a quasi-experimental pre- post-test without control group method. Respondents amounted to 42 people w...
['Adaptation, Psychological', 'Adult', 'Earthquakes', 'Female', 'Humans', 'Indonesia', 'Male', 'Middle Aged', 'Models, Psychological', 'Nurses', 'Psychiatric Nursing', 'Self Report', 'Stress Disorders, Post-Traumatic', 'Young Adult']
30,115,351
[['F01.058'], ['M01.060.116'], ['G01.311.250', 'N06.230.100.230.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.145.380', 'Z01.639.580'], ['M01.060.116.630'], ['E05.599.695'], ['M01.526.485.650', 'N02.360.650'], ['H02.478.676.710', 'N02.421.533.778'], ['E05.318.308.980.500', 'N05.715.360.300.800.500',...
['Psychiatry and Psychology [F]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]']
0
1
0
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Escherichia coli MutY protein has a guanine-DNA glycosylase that acts on 7,8-dihydro-8-oxoguanine:guanine mispair to prevent spontaneous G:C-->C:G transversions.
Low rates of spontaneous G:C-->C:G transversions would be achieved not only by the correction of base mismatches during DNA replication but also by the prevention and removal of oxidative base damage in DNA. Escherichia coli must have several pathways to repair such mismatches and DNA modifications. In this study, we a...
['Base Pair Mismatch', 'Base Sequence', 'Chromosome Mapping', 'Cloning, Molecular', 'DNA Glycosylases', 'DNA Mutational Analysis', 'DNA Repair', 'Escherichia coli', 'Genes, Reporter', 'Guanine', 'Mutagenesis, Insertional', 'N-Glycosyl Hydrolases', 'Oligonucleotides', 'Phenotype', 'Recombinant Fusion Proteins', 'Sequenc...
9,753,736
[['G05.365.590.060'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.393.183'], ['E05.393.220'], ['D08.811.074.249', 'D08.811.277.450.430.099'], ['E05.393.760.700.300'], ['G02.111.222', 'G05.219'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.435'], ['D03.633.100.759.7...
['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Organisms [B]']
0
1
0
1
1
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1
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1
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Determination of trace labile copper in environmental waters by magnetic nanoparticle solid phase extraction and high-performance chelation ion chromatography.
Cobalt magnetic nanoparticles surface functionalised with iminodiacetic acid were evaluated as a nano-particulate solid phase extraction absorbent for copper ions (Cu(2+)) from environmental water samples. Using an external magnetic field, the collector nanoparticles could be separated from the aqueous phase, and adsor...
['Adsorption', 'Chelating Agents', 'Chromatography', 'Cobalt', 'Copper', 'Imino Acids', 'Magnetic Phenomena', 'Metal Nanoparticles', 'Rain', 'Seawater', 'Solid Phase Extraction', 'Water Pollutants, Chemical']
25,640,140
[['G01.030', 'G02.020'], ['D27.505.519.914.500', 'D27.720.832.500'], ['E05.196.181'], ['D01.268.556.185', 'D01.268.956.155', 'D01.552.544.185'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D02.241.081.583', 'D02.491.485', 'D12.125.072.401'], ['G01.358'], ['J01.637.512.600.500'], ['G16.500.175.859', 'G1...
['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]']
0
0
0
1
1
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1
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1
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How to Distinguish Conformational Selection and Induced Fit Based on Chemical Relaxation Rates.
Protein binding often involves conformational changes. Important questions are whether a conformational change occurs prior to a binding event ('conformational selection') or after a binding event ('induced fit'), and how conformational transition rates can be obtained from experiments. In this article, we present gene...
['Computational Biology', 'Models, Molecular', 'Protein Binding', 'Protein Conformation', 'Proteins']
27,636,092
[['H01.158.273.180', 'L01.313.124'], ['E05.599.595'], ['G02.111.679', 'G03.808'], ['G02.111.570.820.709'], ['D12.776']]
['Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]']
0
0
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1
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Point mutations in Staphylococcus aureus PBP 2 gene affect penicillin-binding kinetics and are associated with resistance.
In Staphylococcus aureus, penicillin-binding protein 2 (PBP 2) has been implicated in non-PBP 2a-mediated methicillin resistance. The PBP 2 gene (pbpB) was cloned from an expression library of a methicillin-susceptible strain of S. aureus (209P), and its entire sequence was compared with that of the pbpB gene from stra...
['Amino Acid Sequence', 'Bacterial Proteins', 'Carrier Proteins', 'Gene Library', 'Hexosyltransferases', 'Kinetics', 'Methicillin Resistance', 'Molecular Sequence Data', 'Multienzyme Complexes', 'Muramoylpentapeptide Carboxypeptidase', 'Penicillin-Binding Proteins', 'Penicillins', 'Peptidyl Transferases', 'Point Mutati...
7,695,289
[['G02.111.570.060', 'L01.453.245.667.060'], ['D12.776.097'], ['D12.776.157'], ['G05.360.325'], ['D08.811.913.400.450'], ['G01.374.661', 'G02.111.490'], ['G06.099.225.500.600.525', 'G06.225.347.500.600.525', 'G07.690.773.984.269.347.500.600.525'], ['L01.453.245.667'], ['D05.500.562', 'D08.811.600'], ['D08.811.277.656.3...
['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]']
0
1
0
1
0
0
1
0
0
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1
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[Transposition of gracilis muscle for treatment of recurrent anal and rectovaginal fistula].
BACKGROUND: Rectovaginal fistula is defined as a result of an abnormal connection between the rectum and vagina. It is often a result of inflammatory bowel disease, iatrogenic illness, malignancy or trauma. Rectovaginal fistula treatment is dependent on the classification of the fistula (simple or complex). There are f...
['Adult', 'Female', 'Humans', 'Leg', 'Middle Aged', 'Muscle, Striated', 'Rectal Fistula', 'Rectovaginal Fistula', 'Recurrence']
19,919,795
[['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.500'], ['M01.060.116.630'], ['A10.690.552'], ['C06.267.550.600', 'C06.405.469.471.600', 'C06.405.469.860.752', 'C23.300.575.185.550.600'], ['C06.267.550.600.650', 'C06.405.469.471.600.650', 'C06.405.469.860.752.650', 'C13.351.500.894.767.2...
['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]']
1
1
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[The effect of an alpha-tocopherol analog, MDL 73404, on myocardial bioenergetics].
The authors investigated the effect of the synthetic analogue of MDL 73,404 alpha-tocopherol on bioenergetic processes of the cardiac muscle in a control group of rats. After a 10-day application of the presented preparation they analyzed the following parameters of energetic metabolism: ATP, ADP, AMP and inorganic pho...
['Adenine Nucleotides', 'Adult', 'Aged', 'Aged, 80 and over', 'Animals', 'Cardiovascular Agents', 'Energy Metabolism', 'Female', 'Free Radical Scavengers', 'Humans', 'Hypoxanthine', 'Hypoxanthines', 'Inosine', 'Male', 'Middle Aged', 'Myocardium', 'Phosphates', 'Rats', 'Rats, Wistar', 'Vitamin E', 'Xanthine', 'Xanthines...
8,769,068
[['D03.633.100.759.646.138', 'D13.695.667.138', 'D13.695.827.068'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050'], ['D27.505.954.411'], ['G03.295'], ['D27.505.519.217.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03.633.100.759.758.399.475'], ['D03.633.100.759.758.399'], ['D03....
['Chemicals and Drugs [D]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]']
1
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